item: #1 of 161 id: cord-000549-qwhaesfk author: Hurley, Walter L. title: Perspectives on Immunoglobulins in Colostrum and Milk date: 2011-04-14 words: 11813 flesch: 35 summary: Vaccine Analysis of bovine immunoglobulin G in milk, colostrum and dietary supplements: A review Immune components of bovine colostrum and milk The mucosal immune system and its integration with the mammary glands Immune milk-A historical survey A review of the literature on some aspects of immune milk Bovine milk antibodies for health Bovine colostrum as a biologic in clinical medicine; a review-Part I: Biotechnological standards, pharmacodynamic and pharmacokinetic characteristics and principles of treatment Bovine colostrum as a biologic in clinical medicine; a review-Part II: Clinical studies Bovine and human-derived passive immunization could help slow a future avian influenza pandemic Vaccines and milk immunoglobulin concentrates for prevention of infectious diarrhea Potential for immunological supplementation of foods Passive protection against diarrhea disease Passive and active protection against disorders of the gut Passive immunity against human pathogens using bovine antibodies Preventing infectious disease with passive immunization Maternal antibodies, childhood infections, and autoimmune diseases Regulation of immunoglobulin transfer into mammary secretions of ruminants Allergenicity of orally administered preparations in food-allergic children Effects of a milk-based bioactive micronutrient beverage on pain symptoms and activity of adults with osteoarthritis: A double-blind, placebo-controlled clinical evaluation Analytical approach to determination of safety of milk ingredients from hyperimmunized cows Protection against cholera in breast-fed children by antibodies in breast milk Protection of breast-fed infants against Campylobacter diarrhea by antibodies in human milk Vaccines for preventing enterotoxigenic Escherichia coli infections in farm animals Immunity to Escherichia coli in pigs: Antibody secretion by the mammary gland after intramammary or intramuscular vaccination with E. coli vaccine The effect of oral immunization on the population of lymphocytes migrating to the mammary gland of the sow Survey of immunoglobulin G content and antibody specificity in cow's milk from British Columbia Prevention of rotavirus infection by cow colostrum containing antibody against human rotavirus Prevention of rotavirus infection by oral administration of cow colostrum containing antihumanrotavirus antibody Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: A double-blind, controlled clinical trial Passive immunization of children with bovine colostrum containing antibodies to human rotavirus Treatment of infantile E. coli gastroenteritis with specific bovine anti-E. coli milk immunoglobulins Efficacy of bovine milk immunoglobulin concentrate in preventing illness after Shigella flexneri challenge Hyperimmune bovine colostrum in the treatment of shigellosis in children: A double-blind, randomized, controlled trial Protection by milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coli Milk immunoglobulin with specific activity against purified colonization factor antigens can protect against oral challenge with enterotoxigenic Escherichia coli Lack of prophylactic efficacy of an enteric-coated bovine hyperimmune milk product against enterotoxigenic Escherichia coli challenge administered during a standard meal Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, Shiga toxin-producing E. coli, and E. coli expressing intimin and hemolysin Antibodies from colostrum in oral immunotherapy Immunization against dental caries Effective immunity to dental caries: Passive transfer to rats of antibodies to Streptococcus mutans elicits protection Concentrated bovine colostral whey proteins from Streptococcus mutans/Strep. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. keywords: antigen; binding; bovine; bovine colostrum; coli; colostrum; cows; gland; heat; human; iga; igg; immunoglobulin; mammary; milk; protection; receptor; species; transport; treatment cache: cord-000549-qwhaesfk.txt plain text: cord-000549-qwhaesfk.txt item: #2 of 161 id: cord-002005-35c6mak0 author: Parker, Philip D. title: What Effect Did the Global Financial Crisis Have Upon Youth Wellbeing? Evidence From Four Australian Cohorts date: 2016-02-08 words: 7653 flesch: 48 summary: Age effects are concerned with how old an individual is, cohort effects are concerned with the shared experiences of those who grow up in a similar historical context, whereas period effects are concerned with the impact of particular events that occur at a given time in history (see Schoon, 2006; Yang, 2008) . As noted above, we thus make the assumption that cohort effects are negligible. keywords: age; cohort; domains; effects; gfc; impact; life; people; period; research; wellbeing cache: cord-002005-35c6mak0.txt plain text: cord-002005-35c6mak0.txt item: #3 of 161 id: cord-002643-y5et8pqg author: Dong, Xiaoxv title: Cassiae semen: A review of its phytochemistry and pharmacology date: 2017-06-29 words: 6205 flesch: 21 summary: In rats fed a high-cholesterol diet Effect of Semen Cassiae extracts on expression of lipogenesis genes in hyperlipidemia model mice Study on the chemical constitutions of reducing blood lipid in Cassiae Semen The active ingredients of reducing blood lipid in Semen Cassia Extraction and identification of an antioxidative component from Jue Ming Zi (Cassia tora L Effects of protein and anthraquinone glucosides from Cassia seed on serum lipid of hyperlipidemia rats Effects of anthraquinones from Cassia obtusifolia L. on cholesterol biosynthesis in cells Composition, characteristics, and in-vitro physiological effects of the water-soluble polysaccharides from Cassia seed Extract of Cassiae semen attenuates diabetic nephropathy via inhibition of advanced glycation end products accumulation in streptozotocin-induced diabetic rats Effects of CS, a BuOH-Soluble Fraction of Cassiae Semen Methanolic Extract, on COX-2 Expression in Renal Cortex of STZ-Induced Diabetic Rats and Cultured Glomerular Mesangial Cells Inhibitory Effects of Cassia Seed on the Renal Fibrosis in Diabetic Rats The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice The seed extract of Cassia obtusifolia offers neuroprotection to mouse hippocampal cultures Cassia obtusifolia seed ameliorates amyloid β-induced synaptic dysfunction through anti-inflammatory and Akt/GSK-3β pathways Cassiae semen, a seed of Cassia obtusifolia, has neuroprotective effects in Parkinson's disease models Effect of protein and anthraquinone glucosides from Semen Cassiae on learning and memory capacity and related substances of senile mice induced by D-galactone Jiangsu New Medical College: Encyclopedia of Chinese MateriaMedica, I. Shanghai Science and Technology Press Plants with liver protective activities (I) Liver-protective and bowel-lubricating and defecation-promoting effects of crude and processed Semen Cassiae Experimental Study on Protective Effect of Semen Cassiae Extract Against Acute Liver Injury Study on the protective effect of Cassiae Semen extract against alcohol-induced acute liver injury in mice Anthraquinones isolated from Cassia tora (Leguminosae) seed show an antifungal property against phytopathogenic fungi In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases Growth responses of Cassia obtusifolia toward human intestinal bacteria Primary study on inhabiting of the extracts from Cassia obtusifolia seeds against Fusarium oxysporum and Botrytis cinerea Antioxidant Effects of Extracts from Cassia tora L. Prepared under different degrees of roasting on the oxidative damage to biomolecules Antioxidant properties of water extracts from Cassia tora L. The structures of two new anthraquinone glycosides Two new glycosides from the seeds of Cassia obtusifolia Effect of polysaccharides of cassiae seeds on the intestinal microflora of piglets Experiment study of total anthraquinone in Cassiae Semen on lipid peroxidation and PPAR-gamma expression in liver tissues of rats with alcoholic fatty liver Simultaneous determination of 4 major components in Cassiae Semen obtusifoline by HPLC Chinese) Extraction and identification of an antioxidative component from Jue Ming Zi (Cassia tora L Hypolipidemic activity of seeds of Cassia tora Linn In vitro antimutagenic effects of anthraquinone aglycones and naphthopyrone glycosides from Cassia tora Naphthopyrone glucosides from the seeds of Cassia tora with inhibitory activity on advanced glycation end products (AGEs) formation Extract of Cassiae semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus Cassia tora: A phyto-pharmacological overview Antiallergic agent from natural sources. keywords: activity; addition; anthraquinones; cassiae; cassiae semen; compounds; constituents; effects; extract; obtusifolia; seeds; semen; studies; tora cache: cord-002643-y5et8pqg.txt plain text: cord-002643-y5et8pqg.txt item: #4 of 161 id: cord-004584-bcw90f5b author: None title: Abstracts: 8th EBSA European Biophysics Congress, August 23rd–27th 2011, Budapest, Hungary date: 2011-08-06 words: 106959 flesch: 38 summary: to that of cell proteins (amide II band at *1550 cm -1 ) Membrane proteins and peptides are acting in an environment rich in other proteins or peptides. keywords: acid; actin; activation; activity; affinity; aggregation; amino; amyloid; analysis; applications; approach; assembly; associated; atomic; bilayer; binding; biological; cancer; cell; cell membrane; cell surface; chain; changes; channel; charge; chemical; cholesterol; complex; complexes; composition; compounds; concentration; conditions; conformational; control; correlation; data; delivery; detection; development; diffusion; distribution; dna; domain; drug; dynamics; effect; electron; energy; environment; enzyme; experiments; expression; fast; field; fluorescence; force; formation; free; function; fusion; gene; group; human; hydrophobic; imaging; increase; influence; institute; interaction; key; kinetics; laser; level; ligand; light; lipid; lipid membranes; liposomes; living; magnetic; major; measurements; mechanism; membrane; membrane binding; membrane interaction; membrane protein; membrane structure; membrane surface; method; microscopy; model; model membrane; molecular; molecules; nanoparticles; native; network; new; nmr; non; novel; number; order; organization; parameters; peptide; phase; plasma membrane; potential; presence; processes; properties; protein; protein complex; protein dynamics; protein interactions; protein structure; proton; range; rate; ray; reaction; receptor; region; regulation; research; residues; resolution; response; results; role; scattering; self; signal; simulations; sites; size; species; specific; spectra; spectroscopy; stability; state; structure; studies; study; substrate; surface; system; techniques; temperature; terminal; time; transfer; transition; transport; type; understanding; university; use; vesicles; vitro; vivo; water; work cache: cord-004584-bcw90f5b.txt plain text: cord-004584-bcw90f5b.txt item: #5 of 161 id: cord-004948-ad3i9wgj author: None title: 7th International Congress on Amino Acids and Proteins : Vienna, Austria, August 6–10, 2001 date: 2001 words: 73789 flesch: 41 summary: After the performic acid oxidation and the 6 M HCl hydrolysis of the protein, OPA/TATG (o-phthaldialdehyde/tetra-O-acetyl-1-thio--D-glucopiranoside) precolumn derivatisation method was used, and the enantiomers of sulphur containing amino acids were separated by RP-HPLC (LiChrosphere 100 RP-18e, 125 ϫ 4 mm, 5 µm column, Merck-Hitachi LaChrom HPLC). The dominant ones are water, ethanol, glycerol, sugars, organic acids, and various ions, while amino acids are present at much lower concentration. keywords: acids; activation; activities; activity; addition; administration; amino acid; analysis; animals; antagonists; apoptosis; approach; arginine; binding; biological; blood; brain; cancer; cell; chain; changes; clinical; complex; compounds; concentration; conditions; content; control; cysteine; data; decrease; department; derivatives; development; disease; dna; dopa; effect; enzyme; ethanol; experiments; expression; following; formation; free; function; gaba; gel; gene; glucose; glutamate; glutamine; group; growth; human; identification; increase; inhibition; institute; leucine; levels; liver; lysine; mass; mechanism; membrane; metabolism; methionine; method; mice; model; molecular; mrna; new; nmda; non; number; patients; peptide; plasma; polyamines; present; production; properties; proteins; rats; reaction; receptor; reduced; release; research; response; results; role; samples; sequence; stress; structure; studies; study; substrate; synthesis; system; taurine; time; tissue; transport; treatment; tumor; type; university; uptake; vitamin; vitro; vivo cache: cord-004948-ad3i9wgj.txt plain text: cord-004948-ad3i9wgj.txt item: #6 of 161 id: cord-005080-r01ii1bu author: Butler, Colin D. title: Human Health, Well-Being, and Global Ecological Scenarios date: 2005-02-22 words: 5043 flesch: 39 summary: Both long-distance dust transport and more localized air pollution are also related to ecosystem service change and have been linked with a number of diseases, including asthma and atopy (Monteil 2002) . Inevitably, ecosystem service changes that contribute to modulated effects will be embedded in a mosaic of social, economic, and political cofactors. keywords: change; disease; ecosystem; effects; failure; health; human; income; populations; scenarios; services cache: cord-005080-r01ii1bu.txt plain text: cord-005080-r01ii1bu.txt item: #7 of 161 id: cord-005814-ak5pq312 author: None title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 words: 179325 flesch: 51 summary: Leukemia inhibitory factor (LIF), a growth factor recently recognised as a polyfunctional cytokine integrated in cytokine networks was measured in unconcentrated BALF of patients from different patient groups. It is difficult to generalize on intensive care units as different patient groups are in different ICUs aud there are great changes from one hospital to another and from one country to another. keywords: activity; acute; administration; admission; adult patients; age; aim; airway; analysis; apache; application; ards patients; arf; arterial; artery; assess; average; baseline; blood; blood flow; blood pressure; blood volume; breathing; cardiac; care patients; care unit; cases; catheter; cerebral; changes; chest; children; clinical; compliance; complications; concentration; conclusions; conditions; constant; control group; control patients; copd patients; correlation; course; cpb; criteria; critical; cvp; daily; damage; data; days; death; death patients; decrease; diagnosis; difference; disease; dose; drugs; duration; dysfunction; effect; emergency; end; evaluation; exchange; factors; failure; failure patients; findings; flow; fluid; following; frequency; function; gas; gastric; general; good; group; group b; group ii; group patients; h20; head; heart; hemodynamic; hepatic; hospital; hours; hypertension; icp; icu patients; iii; ill; illness; improvement; incidence; increase; index; infection; influence; infusion; injury; intensive; introduction; intubation; lactate; left; levels; life; liver; lung; male; management; map; mean; measurements; median; medical; methods; min; minutes; mmhg; model; monitoring; mortality; mortality rate; muscle; myocardial; need; negative; new; non; normal; number; objectives; onset; operation; order; organ; outcome; output; oxygen; oxygenation; p =; p<0.05; pao2; parameters; patients; patients methods; pattern; peep; perfusion; period; phase; phi; plasma; population; position; postoperative; presence; present; pressure; pressure support; procedure; protocol; pts; pulmonary; rain; range; rate; rats; reduction; renal; resistance; respiratory; response; results; right; risk; risk patients; samples; saps; score; sepsis; septic; serum; severe; severity; shock; shock patients; signs; specific; standard; status; stay; studies; study; study group; study period; subjects; support; surgery patients; surgical; survival; survivors; syndrome; system; systemic; technique; temperature; test; therapeutic; therapy; time; tissue; total; tracheal; transplantation; trauma patients; treatment; tube; type; unit; university; use; values; variables; vascular; vein; venous; ventilation; ventricular; volume; weaning; years cache: cord-005814-ak5pq312.txt plain text: cord-005814-ak5pq312.txt item: #8 of 161 id: cord-006082-x1kankxd author: Romero, Cesar A. title: Novel RAAS agonists and antagonists: clinical applications and controversies date: 2015-02-10 words: 8437 flesch: 35 summary: Abbreviations: AT1, type-1 angiotensin II receptor; AT2, type-2 angiotensin II receptor; IRAP, leucyl-cystinyl aminopeptidase (also known as insulin-regulated membrane aminopeptidase or insulin-responsive aminopeptidase); MAS1, proto-oncogene Mas; RAAS, renin-angiotensin-aldosterone system. Abbreviations: ACE, angiotensin-converting enzyme; ACE2, angiotensin-converting enzyme 2; Ang, angiotensin; ARB, angiotensin receptor blocker; ARN, angiotensin receptorneprilysin; AT1, type-1 angiotensin II receptor; AT2, type-2 angiotensin II receptor; IRAP, leucyl-cystinyl aminopeptidase (also known as insulin-regulated membrane aminopeptidase or insulin-responsive aminopeptidase); MAS1, proto-oncogene Mas; RAAS, renin-angiotensin-aldosterone system. keywords: ace; aldosterone; ang; angiotensin; blood; effects; failure; heart; hypertension; inhibitors; levels; patients; pressure; raas; receptor; renin cache: cord-006082-x1kankxd.txt plain text: cord-006082-x1kankxd.txt item: #9 of 161 id: cord-006192-bqwchhwk author: Persson, Carl G. A. title: Plasma exudation and asthma date: 1988 words: 7211 flesch: 31 summary: The microcirculation of the tracheal mucosa The role of some higher peptides in inflammation The inflammatory response A study of plasma proteins in the sol phase of sputum from patients with chronic bronchitis Bradykinin and prostaglandin Ex, E2 and F2-induced macromolecular leakage in the hamster cheek pouch The effects of intermittent and continuous stimulation of microvessels in the cheek pouch of hamsters with histamine and bradykinin on the development of venular leaky sites Mechanism of ionophore A23187 induction of plasma protein leakage and of its inhibition by indomethacin Chronic obstructive lung disease. However, the tracheobronchial venular endothelium, which regulates airway inflammatory plasma leakage, has not been considered an important effector cell of the lung. keywords: airway; asthma; asthmatic; bronchial; cells; edema; effects; endothelial; inflammatory; leakage; mediators; permeability; plasma; proteins; vascular cache: cord-006192-bqwchhwk.txt plain text: cord-006192-bqwchhwk.txt item: #10 of 161 id: cord-006226-fn7zlutj author: None title: Abstracts of the 4th annual meeting of the German Society of Clinical Pharmacology and Therapy: Hannover, 14–17 September 1994 date: 1994 words: 25130 flesch: 47 summary: The effects were correlated with the %-~l-adrenoceptor occupancies estimated using a standard Emax-model (sigmoidicity=l) from the concentrations of active substrate in plasma determined by I~l-adrenoceptor specific radioreceptor assay. With regard to group I) the highest expenditures nccured in hospitals A and B whereas drug costs in C -E were 1/3 less and came to only 20% in hospital F. keywords: acid; activity; aggregation; blood; cell; clinical; concentrations; cost; data; disease; dose; drug; effects; excretion; function; group; hours; human; inhibition; mean; metabolites; method; min; patients; placebo; plasma; platelet; products; protein; rate; release; results; samples; serum; studies; study; therapy; time; total; treatment; urinary; urine; use; vitro; volunteers cache: cord-006226-fn7zlutj.txt plain text: cord-006226-fn7zlutj.txt item: #11 of 161 id: cord-006229-7yoilsho author: None title: Abstracts of the 82(nd) Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 18(th) Annual Meeting of the Network Clinical Pharmacology Germany (VKliPha) in cooperation with the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e.V. (AGAH) date: 2016-02-06 words: 134020 flesch: 40 summary: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by a metabolic shift towards enhanced aerobic glycolysis and hence, increased lactate production. Further studies will be performed to clarify whether silver ions and/or silver nanoparticles could affect the specific N-acetylation of arylamines in human cells. keywords: acid; activation; activity; addition; agents; agonist; aim; analysis; animal; anti; approach; assay; assessment; background; barrier; binding; blood; body; brain; camp; cancer; cancer cells; cardiac; cell death; cell line; cells; cgmp; changes; channels; chemical; chronic; clinical; complex; compounds; concentrations; conclusion; conditions; contrast; control; culture; current; damage; data; days; death; development; differences; different; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; experiments; exposure; expression; factor; fibroblasts; findings; flow; fold; food; formation; fret; function; g protein; gene; germany; group; growth; health; heart; human; impact; increase; induction; inflammation; influence; inhibition; inhibitors; insulin; interaction; intracellular; kidney; levels; line; liver; loss; low; lung; mcpd; mechanisms; membrane; metabolism; metabolites; methods; mice; migration; model; mouse; mrna; nanoparticles; neurons; new; non; novel; number; oct1; order; p<0.05; parameters; pathways; patients; phosphorylation; plasma; platelet; potential; presence; present; primary; processes; products; proliferation; properties; protein; protein expression; rats; receptor; receptor activation; reduced; reduction; regulation; release; research; resistance; response; results; risk; role; samples; set; signaling; skin; small; specific; stimulation; stress; studies; study; substances; system; target; test; testing; therapy; time; tissue; total; toxicity; transcription; treatment; tumor; type; uptake; vitro; vivo; vs.; weight cache: cord-006229-7yoilsho.txt plain text: cord-006229-7yoilsho.txt item: #12 of 161 id: cord-006230-xta38e7j author: None title: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V. date: 2012-02-22 words: 136000 flesch: 40 summary: In in-vitro studies on rat and canine mast cells and human mast cell leukemia cells HMC1.2 BZ at micromolar concentrations inhibited mediator release which appeared to be related to an inhibition of the intracellular cAMP pathway. Previous work showed that mouse cells lacking the immediate-early gene c-fos are hypersensitive to ultraviolet (UVC) light. keywords: acid; activation; activity; acute; addition; adducts; agonist; aim; analysis; animals; anti; apoptosis; approach; assay; assessment; binding; blood; brain; calcium; camp; cancer; cancer cells; cardiac; cell line; cells; cellular; cgmp; changes; channels; chronic; clinical; complex; compounds; concentration; conclusion; conditions; contrast; control; current; damage; data; days; death; decrease; deficient; development; differences; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; evidence; experiments; exposure; expression; factor; failure; family; fibroblasts; findings; fold; food; formation; function; für; g protein; gene; gene expression; germany; glucose; growth; health; heart; human; hypertrophy; increase; induction; inflammation; inhibition; inhibitors; institut; insulin; interaction; intracellular; kidney; kinase; leads; levels; like; line; liver; loss; low; lung; macrophages; mechanisms; membrane; methods; mice; model; mouse; mrna; muscle cells; mutations; nanoparticles; ndpk; non; novel; number; pain; pathway; patients; pcr; pharmakologie; phosphorylation; plasma; potential; presence; present; pressure; primary; processes; production; products; proliferation; promoter; properties; protein; protein expression; pulmonary; rats; receptor; reduced; regulation; release; response; results; risk; rkip; role; ros; samples; selective; signaling; site; skin; smooth; specific; stimulation; stress; studies; study; substances; subunits; synthesis; system; t cells; target; test; tested; therapy; time; tissue; toxicity; toxikologie; toxin; transcription; transport; treatment; tumor; tumor cells; type; universität; uptake; values; vascular; vitro; vivo; water cache: cord-006230-xta38e7j.txt plain text: cord-006230-xta38e7j.txt item: #13 of 161 id: cord-006391-esnsa4u5 author: None title: Abstracts 5(th) Tripartite Meeting Salzburg/Austria, September 9–11,1982 date: 1982 words: 44873 flesch: 47 summary: Control patients (no ASA) were compared to those receiving 80 or 325 mg. After transplantation patients were followed for a minimum of 3 months and a maximum of 42 months. keywords: acid; activity; acute; animals; bile; blood; blood flow; body; bypass; cases; cells; changes; control; days; dogs; duct; effect; failure; flow; gastric; glucose; graft; group; heart; hepatic; increase; infusion; insulin; kidney; levels; liver; mean; method; min; months; non; normal; operation; patients; plasma; postoperative; present; pressure; rate; rats; rejection; response; results; serum; studies; study; surgery; survival; time; tissue; total; transplantation; treatment; tumor; values; vascular; weeks; weight cache: cord-006391-esnsa4u5.txt plain text: cord-006391-esnsa4u5.txt item: #14 of 161 id: cord-006518-al94gxjw author: Calder, Philip C. title: n−3 Fatty acids, inflammation, and immunity— Relevance to postsurgical and critically III patients date: 2004 words: 10067 flesch: 25 summary: Fish oil did not decrease bacterial translocation across the gut, and so the authors concluded that fish oil must have improved bacterial killing. Comparison Between Young and Older Women The Effect on Human Tumor Necrosis Factor a and Fatty Acids from Vegetable Oil or Fish Oil Prostaglandin E2 Production and T-Cell Function After Fish-Oil Supplementation: Response to Antioxidant Co-supplementation Effects of Dietary Enrichment with Eicosapentaenoic Acid and Docosahexaenoic Acid on In Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function Dietary ω-3 Polyunsaturated Fatty Acids Inhibit Phosphoinositide Formation and Chemotaxis in Neutrophils n-3 Fatty Acids and Cysteinyl-Leukotriene Formation in Humans in vitro, ex vivo and in vivo Manipulation of Platelet Aggregation by Prostaglandins and Their Fatty Acid Precursors: Pharmacological Basis for a Therapeutic Approach Interaction Between Peroxidase and Cyclooxygenase Activities in Prostaglandin-Endoperoxide Synthase Eicosapentaenoic Acid Inhibits Prostaglandin D2 Generation by Inhibiting Cyclo-oxygenase-2 in Cultured Human Mast Cells Effects of Exogenous Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids on the Generation of 5-Lipoxygenase Pathway Products by Ionophore-Activated Human Neutrophils Effect of Docosahexaenoic Acid (DHA) on Arachidonic Acid Metabolism and Platelet Function Docosahexaenoic Acid is a Strong Inhibitor of Prostaglandin but Not Leukotriene Biosynthesis N-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation Pathologic Indicators of Degradation and Inflammation in Human Osteoarthritic Cartilage are Abrogated by Exposure to N-3 Fatty Acids Fatty Acid Substrate Specificities of Human Prostaglandin-Endoperoxide H Synthase-1 and -2 Structure of Eicosapentaenoic and Linoleic Acids in the Cyclooxygenase Site of Prostaglandin Endoperoxidase H Synthase-1 Separation and Quantification of PGE3 Following Derivatization with Panacyl Bromide by High Pressure Liquid Chromatography with Fluorometric Detection Human Neutrophil Chemotactic and Degranulating Activities of Leukotriene B5 (LTB5) Derived from Eicosapentaenoic Acid Characterization and Biologic Properties of 5,12-Dihydroxy Derivatives of Eicosapentaenoic Acid, Including Leukotriene-B5 and the Double Lipoxygenase Product Synthesis of 4-Series and 5-Series Leukotrienes in the Lung Microvasculature Challenged with Escherichia coli Hemolysin: Critical Dependence on Exogenous Free Fatty Acid Supply Impact of Arachidonic Acid Versus Eicosapentaenoic Acid on Exotoxin-Induced Lung Vascular Leakage-Relation to 4-Series Versus 5-Series Leukotriene Generation Alteration of n-3 Fatty Acid Composition in Lung Tissue After Short-Term Infusion of Fish Oil Emulsion Attenuates Inflammatory Vascular Reaction Anti-Inflammatory Lipid Signals Generated From Dietary n-3 Fatty Acids via Cyclooxygenase-2 and Transcellular Processing: keywords: acid; cells; chain; effects; expression; fatty; fish; human; n-3; oil; patients; production; response; sepsis; studies; tnf cache: cord-006518-al94gxjw.txt plain text: cord-006518-al94gxjw.txt item: #15 of 161 id: cord-006636-xgikbdns author: Ühlein, E. title: Übersicht Über neue ernährungswissenschaftliche Publikationen date: 1964-02-01 words: 31083 flesch: 47 summary: im Liehte der mathematisehen Analyse der Bestimmungen der Fleischbcschau yon Schweinefleisch mSglieh? zur Bestimmung der Gesamtjodzahl yon keywords: 1963; absorption; abstr; acid; acid composition; acid metabolism; activity; amino; amino acid; analysis; arch; auf; beef; bei; bei der; bestimmung; blood; body; calcium; carbohydrate; changes; chemical; chick; children; cholesterol; comparison; composition; content; corn; cows; dairy; deficiency; den; der; des; determination; development; die; diet; digestibility; effect; egg; energy; ern; evaluation; excretion; factors; fat; fats; fatty; fed; feeding; feeds; fiber; fish; flour; food; fruit; glucose; growth; hrung; human; influence; intake; iron; lebensmittel; levels; lipids; liver; low; magnesium; malnutrition; meat; metabolism; method; milch; milk; nitrogen; nutrient; nutrition; nutritive; oil; performance; phosphorus; pigs; plant; plasma; potassium; poultry; production; products; protein; quality; r. s.; rats; relation; relationship; requirements; residues; response; s. s.; serum; sheep; sodium; storage; studies; study; temperature; tissue; und; untersuchungen; use; utilization; value; van; vitamin; water; wheat; wirkung; wiss; yon; zinc; zum; zur cache: cord-006636-xgikbdns.txt plain text: cord-006636-xgikbdns.txt item: #16 of 161 id: cord-006987-1hf8vyhz author: Abass, Ahmed O title: Propolis supplementation attenuates the negative effects of oxidative stress induced by paraquat injection on productive performance and immune function in turkey poults date: 2017-10-05 words: 6789 flesch: 36 summary: PR with a daily subcutaneous PQ injection for 7 days (PR+PQ group), or received the experimental PR diet with a daily subcutaneous injection of 0.5 mL sterile saline for 7 days (PR group); while the control poults received a basal diet with a daily subcutaneous saline injection for 7 consecutive days (C group). Native male turkey poults (n = 120, 49-d-old) were randomly assigned into 4 groups: poults received a basal diet with a daily subcutaneous PQ injection of 5 mg/kg BW for 7 consecutive days (PQ group), an experimental diet containing 1 g/kg keywords: c group; diet; effects; et al; group; injection; oxidative; paraquat; performance; poults; pq group; pr+pq; propolis; stress; turkey cache: cord-006987-1hf8vyhz.txt plain text: cord-006987-1hf8vyhz.txt item: #17 of 161 id: cord-007695-a578obgg author: Canning, B.J. title: Sensory Nerves and Airway Irritability date: 2009-05-11 words: 15443 flesch: 25 summary: Matsumoto et al. , 1999 Matsumoto et al. , 2000 Matsumoto et al. , 2005 Matsumoto et al. , 2006 Sudo et al. 2000; Guardiola et al. 2007 ). More recently, Undem (Kollarik et al. 2003; Undem et al. 2004 ) described bronchopul-monary C-fiber subtypes in both guinea pigs and mice. keywords: activation; airway; asthma; bhr; canning; capsaicin; cough; effects; et al; fibers; guinea; lung; muscle; nerves; pig; pigs; pulmonary; rars; receptor; reflex; role; sensory; smooth; stimuli; subtypes; trpv1; vagal cache: cord-007695-a578obgg.txt plain text: cord-007695-a578obgg.txt item: #18 of 161 id: cord-007798-9ht7cqhu author: Smith, Silas W. title: Drugs and pharmaceuticals: management of intoxication and antidotes date: 2010-02-25 words: 22607 flesch: 29 summary: Similarly, restricting activated charcoal (AC) administration to patients presenting to health care within the first hour post ingestion would exclude up to 90% of poisoned patients from the potential benefits of AC when administered beyond an hour [24, 33] . A small retrospective chart review found no adverse effects or allergic reactions in VPA overdose patients administered carnitine keywords: acetaminophen; acid; acute; administration; benefit; bicarbonate; calcium; cardiac; carnitine; case; channel; charcoal; concentrations; digoxin; doses; drug; effects; glucose; hours; hypoglycemia; i.v; infusion; ingestion; insulin; intoxication; leucovorin; management; methotrexate; mtx; naloxone; octreotide; oral; overdose; patients; poisoning; serum; sodium; studies; study; therapy; toxicity; treatment; use cache: cord-007798-9ht7cqhu.txt plain text: cord-007798-9ht7cqhu.txt item: #19 of 161 id: cord-008777-i2reanan author: None title: ECB12: 12th European Congess on Biotechnology date: 2005-07-19 words: 151661 flesch: 40 summary: During the process development for protein production, short time to market and the demand for cheap processes dominate today's process development. Interdependence of the impact of methanol and oxygen supply on protein production with recombinant Pichia pastoris N.K. Khatri, F. Hoffmann Martin-Luther-University Halle-Wittenberg, Institute for Biotechnology, Halle D-06120, Germany. keywords: acid; acid production; activities; activity; addition; adsorption; affinity; aim; alternative; amino; analysis; animal; ankara; antibody; application; applied; approach; assay; bacillus; bacteria; batch; bed; binding; biology; biomass; bioreactor; biosynthesis; biotechnology; capacity; carbon; case; cell; cell growth; cerevisiae; changes; chemical; chitosan; chromatography; coli; column; complex; composition; compounds; concentration; conditions; control; conversion; cost; cultivation; culture; data; days; degradation; denmark; department; design; development; differences; different; disease; dna; e.g.; effect; efficiency; energy; engineering; environmental; enzymatic; enzyme; enzyme activity; enzyme production; ethanol; ethanol production; experiments; expression; extract; factors; fed; fermentation; fermentation process; flow; flux; food; formation; function; gel; gene; gene expression; genome; glucose; group; growth; health; high; host; human; hydrolysis; identification; increase; induction; industrial; industry; influence; institute; interest; intracellular; knowledge; laboratory; level; limited; line; lipase; liquid; mail; mass; maximum; media; medium; metabolic; metabolites; method; microbial; microorganisms; milk; model; molecular; molecules; natural; network; new; niger; nitrogen; non; novel; number; oil; operation; optimization; order; oxygen; parameters; pathway; pcr; peptide; performance; phase; phosphate; plant; plasmid; potential; presence; present; procedure; process; processes; produce; production; production process; productivity; products; project; properties; protein; protein expression; protein production; purification; quality; range; rate; reaction; recombinant; regulation; removal; research; response; resulting; results; role; samples; scale; science; screening; separation; sequence; signal; source; species; specific; stability; state; step; strains; stress; structure; studies; study; substrate; sucrose; sugar; surface; synthesis; system; target; technical; technique; temperature; therapy; time; total; transfer; treatment; turkey; type; university; use; value; vitro; water; weight; work; yeast; yield cache: cord-008777-i2reanan.txt plain text: cord-008777-i2reanan.txt item: #20 of 161 id: cord-009371-ub4p4ngr author: Mollenhauer, Hilton H. title: Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity date: 1990-05-07 words: 12405 flesch: 45 summary: [46] reported a shift to higher density of Golgi apparatus membranes from monensin-treated barley cells, a response no obvious from work with mammalian cells. These data imply that the monensin-induced swelling of Golgi apparatus cisternae involves a proton gradmnt at or near the mature poles of the Golgi apparatus Because monensin induces a 1 1 Na+/H + exchange, and since the Van't Hoft factors for H + and Na + are practically the same [159] , the osmolanty of the cell content should not increase to cause swelhng without a net proton influx One explanation would be that the pH of Golgi apparatus vesicles is highly regulated Proton translocatlng ATP hydrolyzing enzymes (H +-ATPases) are associated with several components of cells that develop acidic intermrs such as endosomes, coated vesicles, lysosomes, and trans Golgl apparatus Clsternae keywords: animal; apparatus; cells; clsternae; compartments; concentrations; effects; golgi; golgi apparatus; inhibition; membrane; monensin; monensm; muscle; processing; protein; response; secretory; surface; swelling; swollen; trans; transport; vesicles; virus cache: cord-009371-ub4p4ngr.txt plain text: cord-009371-ub4p4ngr.txt item: #21 of 161 id: cord-009385-mcfnhscj author: BLECHA, FRANK title: Rationale for Using Immunopotentiators in Domestic Food Animals date: 2012-11-05 words: 3487 flesch: 24 summary: Indeed, some researchers have suggested that changes in immune function may be a useful indicator of stress in domestic food animals (Kelley, 1985; Siegel, 1985) . The examples described above illustrate the existence of several different immune defects (see Table I ) in neonatal domestic food animals. keywords: animals; bovine; cells; disease; food; macrophages; piglets; pigs; stress; virus cache: cord-009385-mcfnhscj.txt plain text: cord-009385-mcfnhscj.txt item: #22 of 161 id: cord-009694-e59kuwf1 author: None title: Opinion of the Scientific Panel on Animal Health and Welfare (AHAW) on a request from the Commission related with the risks of poor welfare in intensive calf farming systems date: 2006-06-06 words: 40667 flesch: 47 summary: Stabulati In Gabbia Individuale The Provision Of Solid Feeds To Veal Calves: I. Growth Performance, Forestomach Development, And Carcass And Meat Quality Experimental infection of calves and adult cattle with Escherichia coli O157:H7 Effects of handling aids on calf behavior Iron deficiency and the immune response The pituitary-adrenal response to stress in the iron-deficient rat Indicators relevant to animal welfare: a seminar in the C.E.C. programme of coordination of research on animal welfare The behaviour of calves under four levels of lighting The effect of different housing conditions on behavioural and adrenocortical reactions in veal calves From an animal's point of view: motivation, fitness, and animal welfare Phylogenetic characterization of 'Candidatus Helicobacter bovis', a new gastric helicobacter in cattle Rotavirus infections in calves in dairy herds Sucking motivation and related problems in calves Dairy calves discrimination of people based on previous handling Iron supplementation improves iron status and reduces morbidity in children with or without upper respiratory tract infections: a randomized controlled study in Colombo, Sri Lanka Enhancement of clinical signs in experimentally rotavirus infected calves by combined viral infections Group A rotavirus as a cause of neonatal calf enteritis in Sweden Incidence of diarrhea among calves after strict closure and eradication of bovine viral diarrhea virus infection in a dairy herd Enteric infections in veal calves: a longitudinal study on four veal calf units Behaviour and Welfare of Veal Calves in Relation to Husbandry Systems Comparison of four methods of calf confinement. In New Trends in Veal Calf Production The importance of straw for pig and cattle welfare: a review Behavioural and physiological studies on rearing and veal calves Molecular epidemiology of Cryptosporidium parvum and Giardia duodenalis to study the potential for zoonotic transmission Dynamics of bovine respiratory syncytical virus: a longitudinal epidemiological study in dairy herds The prevalence of verotoxins, Escherichia coli O157:H7 and Salmonella in the feces and rumen of cattle at processing Haemoglobin And Haematocrit Levels In Veal Calves Is Anaemia of Veal Calves Normochromic or Hypochromic A comparison of different enrichment media for the isolation of Salmonella dublin from livers, kidneys and muscles of Salmonella-positive veal calves Zusatzfuttering von Stroh an mastkälber The effect of housing system and dietary iron supply on stress physiological measures and resistance against an experimental infection with bovine herpesvirus 1 (BHV1) in veal calves Enkele epidemiologische aspecten van salmonellose bij mestkalveren in Nederland Calves' responses to repeated social regrouping and relocation Does nutritive and non-nutritive sucking reduce other oral behaviors and stimulate rest in calves Nonnutritive oral activities and stress responses of veal calves in relation to feeding and housing conditions Providing social contacts and objects for nibbling moderates reactivity and oral behavior in veal calves The effects of rearing in individual crates on subsequent social behaviour of veal calves Somministrazione Di Un Mangime Solido A Vitelli A Carne Bianca keywords: age; animal; animal welfare; assessment; behaviour; blood; calf; calf welfare; calves; cattle; coli; conditions; dairy calves; development; diarrhoea; diet; disease; e.g.; effect; et al; exposure; factors; farming; fed; feeding; food; group; growth; haemoglobin; health; housing; individual; infection; iron; levels; management; milk; months; pens; production; rearing; replacer; report; risk; rumen; space; studies; sucking; systems; use; veal calves; weaning; weeks; welfare cache: cord-009694-e59kuwf1.txt plain text: cord-009694-e59kuwf1.txt item: #23 of 161 id: cord-009703-ampqjbqw author: Chacón‐Labella, Julia title: Plant domestication disrupts biodiversity effects across major crop types date: 2019-07-03 words: 6482 flesch: 37 summary: (2014) suggest that crop plants might be less suited to over-yielding in mixtures, and might benefit less from biodiversity effects than their wild progenitors. These differences between crop plants and wild progenitors might arise either from directional selection in crops, or from reduced plasticity after domestication in certain traits , which remains to be investigated. keywords: biodiversity; crops; domestication; effects; et al; leaf; mixtures; plant; progenitors; selection; species; wild cache: cord-009703-ampqjbqw.txt plain text: cord-009703-ampqjbqw.txt item: #24 of 161 id: cord-009907-4jfr98wl author: Nelson, Randy J. title: Minireview The influence of season, photoperiod, and pineal melatonin on immune function date: 2007-01-30 words: 9976 flesch: 38 summary: Prolactin elevates the respi- Many interactions between glucocorticoids and immune cell function have been reported in relation to environmental stress [reviewed in Nakono et al., 19871 . Coping with these challenges can also indirectly increase morbidity and mortality by increasing glucocorticoid secretion, which can compromise immune function. keywords: animals; blood; cells; changes; day; disease; effects; et al; function; human; levels; lymphocytes; melatonin; mice; photoperiod; pineal; prolactin; rats; response; studies; summer; system; thymus; winter cache: cord-009907-4jfr98wl.txt plain text: cord-009907-4jfr98wl.txt item: #25 of 161 id: cord-009987-biop7gyd author: Ali, Muhammad title: Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions date: 2017-10-19 words: 7381 flesch: 26 summary: Hepatitis C virus genotypes and hepatitis G virus in hemodialysis patients from Syria: Identification of two novel hepatitis C virus subtypes Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family A review of hepatoprotective plants used in Saudi traditional medicine. Extensive literature survey of hepatoprotective plants clearly indicates that herbal drugs have an enormous potential for the treatment of liver diseases. keywords: activity; ccl; compounds; effects; et al; extract; glutathione; hepatitis; injury; levels; liver; medicine; mice; plants; rats; silymarin; treatment cache: cord-009987-biop7gyd.txt plain text: cord-009987-biop7gyd.txt item: #26 of 161 id: cord-010921-yzv43e8l author: Kaye, Alan David title: Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain date: 2020-04-02 words: 7269 flesch: 40 summary: Thus, use of alpha-2 agonists decreases the sympathetic outflow and counteracts the physiological effects, but the clear mechanism of dexmedetomidine effects is still unclear. In 2008, the FDA approved dexmedetomidine use for procedural sedation and for sedation in non-intubated patients. keywords: analgesia; analysis; anesthesia; dexmedetomidine; dose; effects; mcg; opioid; pain; patients; surgery; use cache: cord-010921-yzv43e8l.txt plain text: cord-010921-yzv43e8l.txt item: #27 of 161 id: cord-013138-4e9vo0xr author: Lang-Illievich, Kordula title: The Effect of Low-Level Light Therapy on Capsaicin-Induced Peripheral and Central Sensitization in Healthy Volunteers: A Double-Blinded, Randomized, Sham-Controlled Trial date: 2020-10-10 words: 3990 flesch: 42 summary: To provide an answer to these questions, we use a human pain model developed to mimic different aspects of clinical pain and to study pain mechanisms in order to examine whether peripheral or central mechanisms contribute to the analgetic effect of LLLT. Indications for LLLT are the improvement of wound healing and tissue regeneration, scarring, and perfusion, as well as pain therapy. keywords: capsaicin; data; effect; level; light; lllt; pain; sensitization; study; therapy cache: cord-013138-4e9vo0xr.txt plain text: cord-013138-4e9vo0xr.txt item: #28 of 161 id: cord-013176-6ckuya1w author: Ninfali, Paolino title: Antiviral Properties of Flavonoids and Delivery Strategies date: 2020-08-21 words: 8135 flesch: 29 summary: Front Antiviral Phytochemicals: An Overview Flavonoids: Promising natural compounds against viral infections Antiviral effects of phytochemicals from medicinal plants: Applications and drug delivery strategies Antiviral activity of Disticella elongata (Vahl) Urb. Concerning the combination of flavonoids in an antiviral cocktail, each phytochemical may be used initially at a concentration of about 0.5 g/day with the aim of reaching an intake of 3 g/day of antiviral flavonoids. keywords: activity; anti; bioavailability; cells; delivery; drugs; effects; flavonoids; hcv; influenza; inhibition; phytochemicals; protein; quercetin; replication; rna; virus cache: cord-013176-6ckuya1w.txt plain text: cord-013176-6ckuya1w.txt item: #29 of 161 id: cord-013333-7jx4t0ol author: Palloni, Alberto title: Impacts of the 1918 flu on survivors' nutritional status: A double quasi-natural experiment date: 2020-10-20 words: 10570 flesch: 48 summary: The parameter θ k measures the difference of effects of flu exposure between those born in high and low severity municipios whereas the difference of effects of exposure between those born in municipios affected by the earthquake and those born in the remaining municipios is, δ The F-test indicates that the total effect of flu exposure is statistically significant (prF o >F � = 79.13 is .0002). keywords: areas; conditions; earthquake; effects; exposure; females; flu; flu severity; growth; height; knee height; municipios; pandemic; severity cache: cord-013333-7jx4t0ol.txt plain text: cord-013333-7jx4t0ol.txt item: #30 of 161 id: cord-013477-dzm4xi21 author: Filardi, Tiziana title: Curcumin: Could This Compound Be Useful in Pregnancy and Pregnancy-Related Complications? date: 2020-10-17 words: 7278 flesch: 30 summary: Systems biology and the recently developed network pharmacology represent new strategies to better comprehend the mechanisms underlying curcumin activities in the human body. The pleiotropic and multi-targeting actions of curcumin have made it very attractive as a health-promoting compound. keywords: antioxidant; curcumin; day; development; effects; exposure; expression; growth; human; levels; pregnancy; reduced; review; treatment; weight cache: cord-013477-dzm4xi21.txt plain text: cord-013477-dzm4xi21.txt item: #31 of 161 id: cord-015021-pol2qm74 author: None title: Third International Congress on the Immune Consequences of Trauma, Shock and Sepsis —Mechanisms and Therapeutic Approaches date: 1994 words: 162543 flesch: 45 summary: Ever since we know the role of endotoxins in the pathophysiology of sepsis, antibodies against the S-and R-LPS have also been detected in sepsis patients. In sepsis patients, the CD]4+/CD16+ cells can become a major population with more than 50% of all monocytes in 3 of 18 patients and with more than 500 cells/mm 3 in 4 of 18 cases. keywords: acid; activation; activity; acute; addition; adhesion; administration; aim; analysis; animals; anti; antibodies; antibody; ards; arterial; bacteria; binding; blood; blood cells; blood levels; blood samples; body; burn; capacity; cardiac; cause; cd14; cells; cellular; challenge; changes; circulating; clinical; clp; complement; complications; concentrations; conclusion; conditions; contrast; control; control group; control patients; correlation; course; csf; cultured; cytokine levels; cytokine production; cytokines; damage; data; days; death; decrease; development; differences; disease; dose; dysfunction; effect; elevated; elisa; endothelial; endotoxin; endotoxin levels; evidence; experimental; expression; factor; failure; flow; following; formation; function; gene; gram; group; growth; gut; hepatic; high; host; hours; hrs; human; il-1; il-6; il-6 levels; il-8; ill; immune; increased; induction; infection; inflammation; inflammatory; infusion; inhibitor; injury; ischemia; leukocytes; levels; lipid; liver; lps; lung; lymphocytes; macrophages; mean; mechanisms; mediators; membrane; methods; mice; model; mof; molecules; monoclonal; monocytes; mortality; multiple; necrosis; negative; neutrophils; new; non; normal; number; operation; organ; organ failure; organ injury; outcome; oxygen; p<0.05; parameters; patients; period; peritoneal; phase; placebo; plasma; plasma levels; plasma tnf; play; pmn; positive; post; postoperative; potential; presence; present; pressure; process; production; protein; pulmonary; rate; rats; receptor; reduced; related; release; reperfusion; response; results; risk; role; saline; samples; score; sepsis; sepsis patients; septic; serum; serum levels; severity; sham; shock; sirs; soluble; specific; state; stimulation; studies; study; surface; surgery; survival; syndrome; synthesis; system; systemic; t cells; test; therapeutic; therapy; time; tissue; tnf; tnf levels; tnf production; tnf release; total; trauma patients; treated; treatment; tumor; type; use; values; vascular; vitro; vivo; wound cache: cord-015021-pol2qm74.txt plain text: cord-015021-pol2qm74.txt item: #32 of 161 id: cord-015147-h0o0yqv8 author: None title: Oral Communications and Posters date: 2014-09-12 words: 73903 flesch: 39 summary: After 3 months of exposures, inflammatory cells in bronchoalveolar lavage fluid were increased in both the HCR-and LCR-smokeexposed(SE) animals compared to air-exposed controls (p<0.001); however there was a 2-3-fold increase in the number of neutrophils and lymphocytes in the LCR-over the HCR-SE group (p<0.001).Histopathology revealed there was greater inflammation and lung damage present in the LCR-versus HCR-SE group (p<0.05). This causes the symptoms of the early phase of AI and the onset of the late phase characterized by the penetration in the inflamed tissue of inflammatory cells, notably the eosinophils. keywords: activation; activity; acute; addition; adhesion; administration; aim; alpha; analysis; animals; anti; antibodies; antibody; arthritis; associated; beta; binding; blood; bone; cancer; cartilage; cells; chronic; complex; conditions; control; cox-2; cytokines; data; day; days; development; disease; dose; effect; expression; factor; function; gene; group; hours; human; il-1b; il-6; immune; increase; induction; inflammation; inflammatory; inhibited; inhibition; inhibitors; injection; injury; joint; kinase; leukocyte; levels; lps; lung; macrophages; mechanisms; mediators; methods; mice; mif; model; molecular; molecules; monocytes; mouse; mrna; neutrophils; new; novel; number; p38; pathways; patients; pcr; plasma; potential; presence; present; production; protein; rats; receptor; reduced; regulation; release; research; response; results; rheumatoid; role; selective; serum; signaling; skin; specific; stimulation; studies; study; synthesis; system; t cells; therapeutic; time; tissue; tnf; tnfa; treatment; tumor; type; university; vitro; vivo cache: cord-015147-h0o0yqv8.txt plain text: cord-015147-h0o0yqv8.txt item: #33 of 161 id: cord-015910-d9gxew91 author: Grimble, Robert F. title: The Interaction Between Nutrition and Inflammatory Stress Throughout the Life Cycle date: 2005 words: 15218 flesch: 33 summary: The effect of aging on glucocorticoid sensitivity of pro-inflammatory cytokine production was examined in elderly men, testosterone-treated elderly men, and young controls. There is now a large body of evidence suggesting that the decline in ovarian function with menopause is associated with spontaneous increases in pro-inflammatory cytokine production. keywords: body; cell; concentrations; cytokine; diabetes; disease; effect; et al; factor; gene; gsh; human; il-6; inflammation; influence; insulin; men; necrosis; patients; plasma; production; protein; response; stress; studies; study; subjects; tnf cache: cord-015910-d9gxew91.txt plain text: cord-015910-d9gxew91.txt item: #34 of 161 id: cord-016372-opojt70e author: DiMarco, Ross F. title: Postoperative Care of the Cardiac Surgical Patient date: 2010 words: 26969 flesch: 39 summary: Mechanisms, predictive factors, and prognostic significance Cardiac surgery Hemodynamic advantage to left atrial epinephrine administration in open heart surgery Lack of renoprotective effects of dopamine and furosemide during cardiac surgery Dopamine therapy for patients at risk of renal dysfunction following cardiac surgery: fact or fiction? Dobutamine and dopamine after cardiac surgery: greater augmentation of myocardial blood flow with dobutamine Effects of dobutamine on hemodynamic and left ventricular performance after cardiopulmonary bypass in cardiac surgical patients The comparative effects of dopamine and dobutamine on ventricular mechanics after coronary artery grafting: a pressure-dimension analysis Hemodynamic comparison of dopamine and dobutamine in the postoperative volume-loaded, pressure-loaded, and normal ventricle Use of amrinone in cardiac surgery patients The effects of amrinone versus dobutamine on myocardial mechanics after hypothermic global ischemia A randomized, blinded trial of amrinone, epinephrine, and amrinone/epinephrine after cardiopulmonary bypass (CPB) Combination high dose amrinone and dopamine in the management of moribund cardiogenic shock after open heart surgery Combined inotropic effects of amrinone and epinephrine after cardiopulmonary bypass in humans Pharmacology of bipyridines: amrinone and milrinone The effect of milrinone on hemodynamics and left ventricular function after emergence from cardiopulmonary bypass A single dose of milrinone facilitates separation from cardiopulmonary bypass in patients with pre-existing left ventricular dysfunction Direct vasodilator effect of milrinone, an inotropic drug, on arterial coronary bypass grafts Vasorelaxant effect of the phosphodiesteraseinhibitor milrinone in the human radial artery used as coronary bypass graft Vasopressin as an alternative to norepinephrine in the treatment of milrinone-induced hypotension Right ventricular dysfunction in low output syndrome after cardiac operations: assessment by transesophageal echocardiography Postoperative Care of the Cardiac Surgical Patient Perioperative use of nesiritide in adult cardiac surgery Nesiritide (BNP) in the management of postoperative cardiac patients Inhaled nitric oxide. keywords: artery; bleeding; blood; bypass; cardiac; cardiopulmonary; cpb; dose; dysfunction; effect; failure; fibrillation; function; heart; heparin; left; mcg; min; output; oxygen; patients; platelet; postoperative; pressure; rate; result; support; surgery; therapy; treatment; ventricular cache: cord-016372-opojt70e.txt plain text: cord-016372-opojt70e.txt item: #35 of 161 id: cord-016444-x2qozizw author: Kato, Masamichi title: Radiofrequency Biology: In vivo date: 2006 words: 24911 flesch: 48 summary: They then studied the effects of microwave exposure on the density of Purkinje cells in the cerebellar uvula. An increase in serum albumin extravasation after microwave exposure was observed only in the group exposed to the highest SAR of 7.5 W/kg and the extravasation was present only immediately after exposure. keywords: blood; body; brain; changes; control; eeg; effects; electromagnetic; et al; exposure; field; field exposure; frequency; ghz; group; heat; human; mhz; microwave exposure; microwaves; min; phone; power; pulsed; rate; rats; results; sar; sham; study; subjects; temperature cache: cord-016444-x2qozizw.txt plain text: cord-016444-x2qozizw.txt item: #36 of 161 id: cord-016460-39yniw0t author: Ben-Chetrit, Eldad title: Colchicine date: 2018-07-31 words: 9583 flesch: 39 summary: The pharmacologic basis of treatment with colchicine in children with familial Mediterranean fever Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis Gout-associated uric acid crystals activate the NALP3 inflammasome Colchicine suppresses neutrophil superoxide production in a murine model of gouty arthritis: a rationale for use of low-dose colchicine Innate immune sensing of bacterial modifications of Rho GTPases by the pyrin inflammasome Interaction of pyrin with 14.3.3 in an isoform-specific and phosphorylation-dependent manner regulates its translocation to the nucleus Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS Technical advance: inhibition of neutrophil chemotaxis by colchicine is modulated through viscoelastic properties of subcellular compartments Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells The effects of colchicine on the progression and regression of encapsulating peritoneal sclerosis Colchicine use in children and adolescents with familial Mediterranean fever: literature review and consensus statement Colchicine is a safe drug in children with familial Mediterranean fever Current trends in colchicine treatment in familial Mediterranean fever Colchicine intoxication clinical pharmacology, risk factors, features and management Colchicine: old and new Estimation of colchicine in a poisoned patient by using high performance liquid chromatography Treatment of severe colchicine overdose with colchicine specific fab fragments Vos FR high flux dialysis membranes improve lipid profile in chronic hemodialysis patients Colchicine clearance by high-flux polysulfone dialyzers ABC drug transporters as molecular targets for the prevention of multidrug resistance and drug-drug interactions Colchicine myotoxicity: case reports and literature review Colchicine use in cyclosporine treated transplant recipients: how little is too much? MDR-and CYP3A4-mediated drug-drug interactions Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects Multiple sequential steps involved in the binding of inhibitors to cytochrome P450 3A4 Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions Acute myopathy in a patient with concomitant use of pravastatin and colchicine Fatal interaction between clarithromycin and colchicine in patients with renal insufficiency: a retrospective study Cytoskeletal myotoxicity from simvastatin and colchicine Rhabdomyolysis in a patient treated with colchicine and atorvastin Possible colchicine rhabdomyolysis in a fluvastatin-treated patient Novel evidence-based colchicine dosereduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 Effect of colchicine on guinea pig intrinsic factor-vitamin B12 receptor Colchicineinduced lactose malabsorption in patients with familial Mediterranean fever Azoospermia caused by colchicine-a case report The effect of colchicine on the spermatogenesis of rabbits A cytogenetic evaluation of long term colchicines therapy in the treatment of familial Mediterranean fever (FMF) Testicular function in patients with familial Mediterranean fever, long-term colchicine treatment Fertility and obstetric history in patients with familial Mediterranean fever on long term colchicine therapy The effect of colchicine on human spermatozoal motility in vitro Colchicine and testicular function in man Urological evaluation of Behçet patients and the effect of colchicine on fertility Azoospermia in FMF patients-the role of colchicine and amyloidosis Daily prophylactic colchicines in familial Mediterranean fever The effect of FMF and colchicine on pregnancies outcome of wives of patients with FMF Familial Mediterranean fever and menstruation Effects of hormone therapy on inflammatory cell adhesion molecules in postmenopausal healthy women Qualitative study of the interaction mechanism of estrogenic drugs with tubulin Safety of colchicine therapy during pregnancy Familial Mediterranean fever and its implications for fertility and pregnancy Colchicine treatment in conception and pregnancy: two hundred and thirty one pregnancies in patients with familial Mediterranean fever Pregnancy outcome after in utero exposure to colchicine Outcome of pregnancies in FMF women with colchicine Breast feeding during colchicine therapy for familial Mediterranean fever Colchicine in breast-milk of patients with FMF Colchicine treatment in familial Mediterranean fever (FMF)-reappraisal after 15 years Colchicine therapy of children with FMF (abstract) Growth and IGF-1 levels of children with familial Mediterranean fever on colchicine treatment EULAR recommendations for the management of familial Mediterranean fever Familial Mediterranean fever is no longer a rare disease in Japan Evidencebased recommendations for the practical management of familial Mediterranean fever Comparison of the efficacy of once-and twice-daily colchicine dosage in pediatric patients with familial Mediterranean fever-a randomized controlled non-inferiority trial High versus low dosing of oral colchicine for early acute gout flare: twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study American College of Rheumatology guidelines for management of gout. When abdominal cramps persist, lowering colchicine dose may be effective. keywords: acute; cells; colchicine; disease; dose; drug; effect; fever; fmf; gout; liver; mediterranean; microtubules; patients; pyrin; study; therapy; treatment; tubulin cache: cord-016460-39yniw0t.txt plain text: cord-016460-39yniw0t.txt item: #37 of 161 id: cord-016742-y7jgjera author: Bauer, Maria title: Cardiovascular Anatomy and Pharmacology date: 2017-07-03 words: 23166 flesch: 38 summary: In low to moderate dose ranges its β 1 -adrenergic effects are predominant, resulting in increased heart rate, increased contractility, and increased cardiac output. Signs of toxicity include extracardiac (primarily central nervous system and gastrointestinal) and cardiac effects. keywords: ace; action; artery; beta; blockers; blood; calcium; cardiac; dose; effects; failure; heart; hypertension; inhibitors; left; myocardial; patients; phase; pressure; pulmonary; rate; receptors; right; septum; treatment; use; valve; vascular; ventricle; ventricular; wall cache: cord-016742-y7jgjera.txt plain text: cord-016742-y7jgjera.txt item: #38 of 161 id: cord-017041-0zxoq68m author: Volochnyuk, Dmitriy M. title: Fluorine-Containing Diazines in Medicinal Chemistry and Agrochemistry date: 2014-06-13 words: 16532 flesch: 40 summary: Several syntheses of Doxifl uridine relied on glycosylation of Fluorouracil derivative 55 . In particular, reaction of pyrimidine derivatives 68 with P 2 S 5 followed by treatment with Raney nickel and gave alkoxy derivative 69 , which was transformed to 38 upon acidic hydrolysis (Scheme 18 ) keywords: acid; activity; agents; cancer; chemistry; chloride; compounds; containing; derivatives; diazines; drug; effect; fluorouracil; hydrolysis; inhibitor; kinase; medicinal; method; phase; preparation; process; pyrimidine; reaction; receptor; rst; scheme; studies; synthesis; treatment; trials; trifl; uorinated; use cache: cord-017041-0zxoq68m.txt plain text: cord-017041-0zxoq68m.txt item: #39 of 161 id: cord-017148-o9qg2qta author: Mocchegiani, Eugenio title: Role of Zinc and Selenium in Oxidative Stress and Immunosenescence: Implications for Healthy Aging and Longevity date: 2019-04-11 words: 14906 flesch: 25 summary: redox independent functions Metallothionein expression in animals: a physiological perspective on function The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA Is vitamin supplementation appropriate in the healthy old? Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes RNA virus quasispecies: significance for viral disease and epidemiology Beneficial effects of oral zinc supplementation on the immune response of old people The role of metallothioneins in carcinogenesis Metallothioneins and cancer Zinc transporters and the cellular trafficking of zinc Influenza-and respiratory syncytial virus-associated morbidity and mortality in the nursing home population Thymic hormone deficiency in normal ageing and Down's syndrome: is there a primary failure of the thymus? Selenium supplementation affects insulin resistance and serum hs-CRP in patients with type 2 diabetes and coronary heart disease Effect of zinc supplementation on in vitro copper-induced oxidation of low-density lipoproteins in healthy French subjects aged 55-70 years: the Zenith Study Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients Zinc supplementation and plasma lipid peroxides in an elderly population The effect of zinc and vitamin A supplementation on immune response in an older population Roles for cell death in zinc deficiency However, increased longevity after zinc supplementation was also reported in the short lived thymectomized and nude mice, which display a negative crude balance of zinc (Mocchegiani et al. 2007 ). keywords: age; aging; antioxidant; cancer; cells; cellular; deficiency; diseases; effects; et al; expression; function; human; levels; mice; proteins; response; role; selenium; status; stress; studies; study; subjects; supplementation; zinc; zinc supplementation cache: cord-017148-o9qg2qta.txt plain text: cord-017148-o9qg2qta.txt item: #40 of 161 id: cord-017499-51yy7y9n author: Freye, Enno title: Mechanism of Action of Opioids and Clinical Effects date: 2008 words: 24978 flesch: 42 summary: It is assumed that opioid receptors mediate Opioid receptors are found in several areas of the brain, particularly in the periaqueductal grey matter, and throughout the spinal cord ( Figure II-9 ). There, opioids act as agonists at highly definite receptor sites, and there is general agreement on the existence of at least three types of opioid receptor sites (Table II-1). keywords: action; activity; addition; affinity; agonist; analgesic; anesthesia; antagonist; binding; brain; cough; depression; dose; drug; effect; fentanyl; figure; following; heroin; increase; morphine; naloxone; nerve; nucleus; opioid; opioid receptor; opium; pain; patients; potency; potent; receptor; response; results; sites; solution; sufentanil; system; use cache: cord-017499-51yy7y9n.txt plain text: cord-017499-51yy7y9n.txt item: #41 of 161 id: cord-017504-rtg7fs82 author: Lim, T. K. title: Punica granatum date: 2012-11-03 words: 31407 flesch: 35 summary: Oral administration of pomegranate juice extract (100 and 300 mg/kg) to angiotensin-II treated rats for 4 weeks signi fi cantly reduced the mean arterial blood pressure and vascular reactivity changes to various catecholamines (Waghulde et al. 2010 ) . The results suggested that pomegranate juice extract could prevent the development of high blood pressure induced by angiotensin-II probably by combating the oxidative stress and antagonizing the physiological actions of angiotensin-II. keywords: acid; activity; administration; antioxidant; cancer; cells; compounds; consumption; content; effect; ellagic; ellagic acid; et al; expression; extract; fruit; fruit extract; glucose; glutathione; granatum; growth; human; inhibition; juice; levels; lipid; mice; oil; oral; patients; peel; peel extract; polyphenols; pomegranate; pomegranate extract; pomegranate fl; pomegranate juice; prostate; protein; punica; punica granatum; punicalagin; rats; results; rind; seed; serum; signi; signi fi; skin; stress; studies; study; total; treatment cache: cord-017504-rtg7fs82.txt plain text: cord-017504-rtg7fs82.txt item: #42 of 161 id: cord-017907-997yo3ni author: Gralinski, Michael title: Methods to Induce Cardiac Hypertrophy and Insufficiency date: 2015-07-28 words: 16692 flesch: 40 summary: The effect of myocardial adaptation to volume overload in the rat A model of chronic heart failure in spontaneous hypertensive rats (SHR) NHE-1 inhibition improves impaired mitochondrial permeability transition and respiratory function during postinfarction remodelling in the rat Angiotensin II receptor blockade attenuates the deleterious effects of exercise training on post-MI ventricular remodelling in rats Proteomic analysis of left ventricular diastolic dysfunction hearts in renovascular hypertensive rats Myocyte cellular hyperplasia and myocytes cellular hypertrophy contribute to chronic ventricular remodelling in coronary artery narrowing-induced cardiomyopathy in rats Selective sensory denervation by capsaicin aggravates adriamycin-induced cardiomyopathy in rats Development of heart failure in chronic hypertensive Dahl rats: focus on heart failure with preserved ejection fraction Regional changes in hemodynamics and cardiomyocyte size in rats with aortacaval fistulas Developing and established hypertrophy Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure Chronic heart failure induced by coronary artery ligation in Lewis inbred rats A simple method for collagen and total protein determination in formalinfixed paraffin-embedded sections Systemic and regional hemodynamic effects of perindopril in experimental heart failure Animal models of chronic heart failure Ventricular enlargement and reduced survival after myocardial infarction Myocardial infarct size and ventricular function in rats Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril Matrix metalloproteinase inhibition improves cardiac dysfunction and remodeling in 2-kidney, 1-clip hypertension Determination of rat heart morphology and function in vivo in two models of cardiac hypertrophy by means of magnetic resonance imaging A canine model of chronic heart failure produced by multiple sequential coronary microembolizations Simple techniques for the surgical occlusion of coronary vessels in the rat Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis Neurohumoral and hemodynamic effects of ibopamine in a rat model of chronic myocardial infarction and heart failure Relation between myocardial β-adrenoceptor density and hemodynamic and neurohumoral changes in a rat model of chronic myocardial infarction: effects of ibopamine and captopril Myosin heavy chain regulation and myocytes contractile depression after LV hypertrophy in aortic-banded mice Prolonged endoplasmatic reticulum stress in hypertrophic and failing heart after aortic constriction. key: cord-017907-997yo3ni authors: Gralinski, Michael; Neves, Liomar A. A.; Tiniakova, Olga title: Methods to Induce Cardiac Hypertrophy and Insufficiency date: 2015-07-28 journal: Drug Discovery and Evaluation: Pharmacological Assays DOI: 10.1007/978-3-319-05392-9_8 sha: doc_id: 17907 cord_uid: 997yo3ni Animal models of cardiac hypertrophy and insufficiency have been reviewed by Hasenfuss (1988), Muders and Elsner (2000), Vanoli et al. (2004), Patten and Hall-Porter (2009), Dubi and Arbel (2010), Gomes et al. (2013), and Szymanski et al. (2012). keywords: angiotensin; animals; aorta; aortic; artery; blood; calcium; cardiac; cardiomyopathy; chronic; dogs; dysfunction; effects; end; et al; expression; failure; heart; heart failure; hypertrophy; inhibition; left; mice; min; model; myocardial; overload; pacing; pressure; rats; study; ventricular; volume; wall cache: cord-017907-997yo3ni.txt plain text: cord-017907-997yo3ni.txt item: #43 of 161 id: cord-017916-wh708hes author: Mocchegiani, Eugenio title: Role of Zinc and Selenium in Oxidative Stress and Immunosenescence: Implications for Healthy Ageing and Longevity date: 2008-08-04 words: 12649 flesch: 27 summary: redox independent functions Responses to mild cold stress are predicted by different individual characteristics in young and older subjects The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes RNA virus quasispecies: significance for viral disease and epidemiology Immunosenescence and the lung Beneficial effects of oral zinc supplementation on the immune response of old people The status of zinc, copper, and metallothionein in cancer patients Zinc transporters and the cellular trafficking of zinc Influenza-and respiratory syncytial virus-associated morbidity and mortality in the nursing home population Nutrition: impact on oral and systemic health Zinc, human diseases and aging Thymic hormone deficiency in normal ageing and Down's syndrome: is there a primary failure of the thymus? Effect of zinc supplementation on in vitro copper-induced oxidation of low-density lipoproteins in healthy French subjects aged 55-70 years: the Zenith Study Metallothionein disulfides are present in metallothioneinoverexpressing transgenic mouse heart and increase under conditions of oxidative stress Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients Zinc supplementation and plasma lipid peroxides in an elderly population The effect of zinc and vitamin A supplementation on immune response in an older population Zinc toxicity Roles for cell death in zinc deficiency Effect of zinc supply Zinc and immunoresistance to infection in aging: new biological tools Zinc, metallothioneins, immune responses, survival and ageing Reversibility of the thymic involution and of age-related peripheral immune dysfunctions by zinc supplementation in old mice Interrelationship among neutrophil efficiency, inflammation, antioxidant activity and zinc pool in very old age Regulation of matrix biology by matrix metalloproteinases Matrix metalloproteinases Postnatal regulation of ZnT-1 expression in the mouse brain Reactive oxygen species, antioxidants, and the mammalian thioredoxin system Selenium, zinc, and thyroid hormones in healthy subjects: low T3/T4 ratio in the elderly is related to impaired selenium status Effect of zinc ions on apoptosis in PBMCs from healthy aged subjects Rapid oxidation of DL-selenomethionine by peroxynitrite Metabolic age modelling: the lesson from centenarians Flow cytometric evaluation of the DNA profile and cell cycle of zinc supplemented human Chang liver cells Human immunosenescence: is it infectious? Effect of dietary selenium deficiency on incidence and size of 1,2-dimethylhydrazine-induced colon tumours in rats Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast Hypopituitary dwarf and athymic nude mice and the study of the relationships among thymus, hormones, and aging Effects of zinc deficiency on Th1 and Th2 cytokine shifts Zinc deficiency in elderly patients Flow cytometric analysis of CD3/TCR complex, zinc, and glucocorticoid-mediated regulation of apoptosis and cell cycle distribution in thymocytes from old mice The importance of selenium to human health keywords: ageing; cancer; cells; deficiency; diseases; effect; et al; expression; high; human; intracellular; low; mice; mocchegiani; mocchegiani et; release; response; role; selenium; status; stress; subjects; supplementation; zinc cache: cord-017916-wh708hes.txt plain text: cord-017916-wh708hes.txt item: #44 of 161 id: cord-018009-8j40876m author: Campbell, Duncan J. John title: ACE Inhibition in Heart Failure and Ischaemic Heart Disease date: 2007 words: 11621 flesch: 30 summary: Campbell et al 1999; Zeitz et al 2003) . Danser et al 1994) . keywords: ace; ace inhibition; angiotensin; bradykinin; cardiac; converting; effects; enzyme; et al; failure; heart; heart failure; infarction; inhibition; inhibitors; levels; patients; plasma; receptor; reduction; role; therapy cache: cord-018009-8j40876m.txt plain text: cord-018009-8j40876m.txt item: #45 of 161 id: cord-018095-for6qa1s author: Chandrappa, Ramesha title: Major Issues of Air Pollution date: 2015-08-22 words: 12589 flesch: 49 summary: World Health Organisation An assessment of global and regional emissions of trace metals to the atmosphere from anthropogenic sources worldwide Air pollution and forest health: Toward new monitoring concepts Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease Global and regional climate changes due to black carbon Air pollution, greenhouse gases and climate change: Global and regional perspectives Coping with climate change: Principles and Asian context Nitrous oxide (N2O): The dominant ozone-depleting substance emitted in the 21st century Critical review on natural global and regional emissions of six trace metals to the atmosphere. This chapter elaborates major issues due to air pollution. keywords: acid; air; air pollution; atmosphere; cause; change; countries; deposition; dust; earth; effect; et al; exposure; health; increase; layer; lead; mercury; ozone; pollutants; pollution; precipitation; rain; region; soil; surface; temperature; water cache: cord-018095-for6qa1s.txt plain text: cord-018095-for6qa1s.txt item: #46 of 161 id: cord-019001-ralxw4ad author: Oishi, Peter title: Diseases of the Pulmonary Vascular System date: 2008-11-15 words: 12802 flesch: 23 summary: Other, less common causes of pediatric pulmonary vascular disease include primary (idiopathic) pulmonary hypertension, hypoxiainduced pulmonary vascular disease, rheumatologic disorders, sickle cell disease, portal hypertension, chronic thromboembolic disease, human immunodefi ciency virus disease, and drug-toxin induced disease. Finally, a genetic disposition appears to be important in some subtypes of pulmonary vascular disease and remains an area of active research. keywords: acute; arterial; blood; disease; effects; endothelial; heart; hypertension; lung; nitric; oxide; patients; pressure; prostacyclin; pulmonary; resistance; therapy; vascular cache: cord-019001-ralxw4ad.txt plain text: cord-019001-ralxw4ad.txt item: #47 of 161 id: cord-022526-j9kg00qf author: Jones, Samuel L. title: Disorders of the Gastrointestinal System date: 2009-05-18 words: 108877 flesch: 36 summary: Abdominal radiographs are reserved for smaller horses and ponies. In addition, one may detect mineral opacity within the colon on abdominal radiographs, particularly in foals, ponies, and small horses. keywords: absorption; acid; activity; acute; addition; administration; adult horses; bacteria; blood; body; bowel; cases; cause; cells; chronic; colic; colitis; colon; colonic; concentration; damage; diagnosis; diarrhea; disease; distention; effects; endothelial; endotoxemia; endotoxin; epithelium; equine; esophageal; esophagus; examination; factors; flow; fluid; foals; gastric; gastrointestinal; horses; hours; human; ileus; impaction; increase; infection; inflammation; inflammatory; injury; intestine; ischemia; lesions; lipopolysaccharide; loss; mediators; motility; mucosal; neutrophils; normal; obstruction; pain; patients; peritoneal; peritonitis; plasma; production; products; protein; proximal; rectal; release; response; result; role; salmonella; secretion; serum; signs; specific; squamous; study; surgery; therapy; tissue; tract; treatment; ulceration; vascular; wall cache: cord-022526-j9kg00qf.txt plain text: cord-022526-j9kg00qf.txt item: #48 of 161 id: cord-022658-mq91h15t author: None title: Executive summary date: 2008-12-30 words: 12010 flesch: 33 summary: Evidence of minimal, persistent inflammation in asymptomatic allergic patients suggests that by inducing ICAM-1, subclinical allergen exposure may incregse the susceptibility of allergic patients to rhinovirus infection, and thereby explain the greater frequency of colds in asthmatic children (30) . Although the use of antihistamines in asthma is still controversial, the new nonsedating agents seem to offer some benefit for allergic patients with concomitant asthma. keywords: agents; airway; allergy; antihistamines; asthma; children; chronic; control; effects; intranasal; loratadine; medications; nasal; patients; performance; rhinitis; symptoms; therapy; topical; treatment; use cache: cord-022658-mq91h15t.txt plain text: cord-022658-mq91h15t.txt item: #49 of 161 id: cord-022889-lv6fy6e6 author: Dávalos, Alberto title: Literature review of baseline information on non‐coding RNA (ncRNA) to support the risk assessment of ncRNA‐based genetically modified plants for food and feed date: 2019-08-07 words: 96106 flesch: 44 summary: In a later observational study, Lukasik et al. evaluated plant miRNAs miR-166a, miR-156a, miR-157a, miR-172a and miR-168a and reported the presence of plant miRNAs in human (n=6) breast milk, both in whole milk and exosomes . This HEN1-dependent 2'-Omethylation on the 3' terminal ribose is a Mg2+ dependent methylation mechanism that will ultimately stabilize miRNAs (Abe et al., 2010; Molnar et al., 2007; Yu et al., 2005; Yang et al., 2006) .The keywords: activity; administration; animals; authors; barriers; biological; blood; bodies; breast; cells; cellular; conclusions; conditions; context; contract; degradation; delivery; dietary; document; dsrna; effects; efsa; et al; european food; exogenous; exosomes; expression; food safety; function; gene; human; immune; information; issues; juliano et; key; levels; literature; mammalian; mice; milk; molecules; mouse; mrna; naked; ncrnas; non; oligonucleotides; oral; output; pathway; plant mirnas; plant ncrna; plant rna; plants; plasma; position; prejudice; presence; present; principle; procedure; proteins; publication; review; rice; rights; rnai; role; safety authority; samples; search; section; serum; silencing; sirna; small; specific; srnas; stability; studies; study; subject; synthetic; system; target; task; tender; tender procedure; tissue; total; transparency; transparency principle; uptake; view; vivo; words; zhang et cache: cord-022889-lv6fy6e6.txt plain text: cord-022889-lv6fy6e6.txt item: #50 of 161 id: cord-022903-08ugoxns author: Jensen, Bent Borg title: Extensive Literature Search on the ‘Effects of Copper intake levels in the gut microbiota profile of target animals, in particular piglets’ date: 2016-05-02 words: 21242 flesch: 46 summary: Feeding high copper diets to germ free pigs has been investigated in one study with growing pigs (P149, Shurson et al., 1990) . High copper diets seem to reduce intestinal cell turnover in germ free pigs while it tended to accelerate intestinal turnover in conventionally reared pigs, perhaps via an interaction with the gut microbiota. keywords: bacteria; content; copper; cuso; diets; document; effect; european food; food safety; kg copper; kg cu; kg cuso; kg feed; pigs; population; rights; safety authority; studies; study cache: cord-022903-08ugoxns.txt plain text: cord-022903-08ugoxns.txt item: #51 of 161 id: cord-022940-atbjwpo5 author: None title: Poster Sessions date: 2016-09-07 words: 241687 flesch: 44 summary: Among used cancer cell lines, ERICD was highly expressed and ARID3A had lower expression in U-2OS (osteosarcoma), A-172 (glioblastoma) and A549 (lung cancer). Clear cell renal cell cancer (ccRCC) with metastases has pour prognosis: 5-year survival is about 9%. keywords: a549 cells; acid; activation; activities; activity; activity levels; acute; addition; administration; affinity; agents; aim; albumin; allele; alterations; alternative; amino; analysis; analysis results; animals; ankara; anti; antibodies; antibody; anticancer; antioxidant; apoptosis; applications; approach; assay; association; bacteria; beta; binding; biology; blood; body; bone; brain; breast cancer; cancer cells; cancer group; cancer patients; cancer stem; cancer treatment; cancers; cause; cell cycle; cell death; cell growth; cell lines; cell proliferation; cell survival; cell viability; changes; characterization; chemical; cholesterol; chronic; clinical; coli; colorectal; combination; comparison; complex; complexes; compounds; concentrations; conclusion; conditions; content; control cells; control group; control study; controls; correlation; culture; curcumin; current; cytotoxic; damage; data; day; days; decrease; department; detection; determination; development; diabetes; differences; differentiation; discussion; disease; dna; domain; dose; drug; effects; elevated; elisa; energy; enzyme; enzyme activity; ethanol; experimental; expression analysis; expression levels; expressions; extract; factor; faculty; family; fat; findings; flow; fluorescence; fold; food; formation; free; function; gene expression; genes; genetic; genome; genotype; glucose; glutathione; group; growth; gsh; health; hours; human; immune; increase; inflammation; inflammatory; inhibition; inhibitors; injury; institute; insulin; interaction; intracellular; introduction; invasion; investigation; ischemia; kinase; laboratory; lead; levels; light; like; lipid; liver; low; lung; male; manner; markers; mass; materials; matrix; mcf-7; mda; mda levels; mean; mechanisms; medical; medicine; medium; membrane; metabolism; methods; methylation; mice; microscopy; migration; mirnas; mitochondrial; model; modified; molecular; molecules; mrna; muscle; mutant; mutations; n =; nanoparticles; negative; non; normal; novel; number; obese; obesity; oil; order; oxidative; oxygen; p =; p-02.08.5; parameters; pathway; patients; pcr; peptide; phase; plant; plasma; play; point; polymorphisms; population; potential; presence; present; process; processes; production; products; profile; progression; promoter; properties; prostate; prostate cancer; protective; protein; protein expression; protein levels; purpose; radical; range; rate; rats; reaction; receptor; recombinant; region; regulation; related; relationship; research; resistance; response; results; risk; role; samples; science; scientific; screening; sequence; serum; serum levels; signaling; site; size; sod; species; specific; stability; stage; status; stem cells; strain; stress; structure; studies; study; study group; subjects; surface; survival; synthesis; system; target; technique; temperature; test; tested; therapeutic; therapy; time; tissue; tnf; total; transcription; treatment; treatment group; tumor; tumor cells; turkey; type; university; use; values; vitamin; vitro; water; weight; western; wild; women; work; years cache: cord-022940-atbjwpo5.txt plain text: cord-022940-atbjwpo5.txt item: #52 of 161 id: cord-023509-tvqpv6fp author: Corrin, Bryan title: Occupational, environmental and iatrogenic lung disease date: 2011-03-02 words: 42595 flesch: 39 summary: Aluminium powder holds a paradoxical position in regard to lung disease. 366 More directly, welders may be exposed to asbestos insulation that they themselves use, while welders of special steel alloys run the risk of metal-induced asthma, metal fume fever, polymer fume fever and the consequences of toxic metal fume inhalation, 367 all of which are described separately in this chapter, as is lung disease in aluminium welders. keywords: acute; air; aluminium; alveolar; analysis; asbestos; asbestos exposure; asbestos fibres; asthma; beryllium; blood; bodies; bronchiolitis; cases; cause; cells; changes; chronic; coal; damage; diffuse; drug; dust; dust exposure; dust pneumoconiosis; effects; electron; emphysema; evidence; exposure; factor; fibres; fibrosis; fig; gas; interstitial; lesions; lung; lung cancer; lung disease; lung injury; lung tissue; macrophages; mineral; non; occupational; oedema; oxygen; particles; patients; pneumoconiosis; pneumonia; pulmonary; risk; silica; silicosis; smoking; study; syndrome; tissue; toxicity; type; water; workers cache: cord-023509-tvqpv6fp.txt plain text: cord-023509-tvqpv6fp.txt item: #53 of 161 id: cord-023528-z9rc0ubj author: Wilkins, Pamela A. title: Disorders of Foals date: 2009-05-18 words: 42606 flesch: 40 summary: A syndrome of bronchointerstitial pneumonia and acute respiratory distress has been described in older foals and appears to be a distinct entity from acute respiratory distress syndrome in neonatal foals in association with sepsis. One can use these measurements and the ultrasonographic appearance of the internal umbilical structures from clinically normal foals as references to diagnose abnormalities of the umbilical structures in neonatal foals. keywords: abnormalities; acute; administration; age; author; birth; blood; care; cases; cell; concentration; days; deformities; diagnosis; diarrhea; disease; effects; equine; failure; fetal; fetus; fluid; foals; function; gastric; horses; hours; human; hypoxia; infants; infection; injury; intravenous; joint; limb; mares; neonatal; neonate; newborn; oxygen; patients; pneumonia; rate; renal; result; risk; sepsis; signs; specific; therapy; treatment; use; ventilation cache: cord-023528-z9rc0ubj.txt plain text: cord-023528-z9rc0ubj.txt item: #54 of 161 id: cord-024111-7yrftdp4 author: Zhang, Runzhi title: Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare date: 2020-04-22 words: 8559 flesch: 23 summary: Ginsenoside compounds K (CK) is one of the metabolites of ginsengoside, which exerts various pharmacological effects, including antiallergic (Shin and Kim, 2005) , antidiabetic (Kim et al., 2014) , anticarcinogenic (Zhou et al., 2010; Zhang et al., 2013) , anti-inflammatory (Joh et al., 2011; Chen et al., 2014) , and antiaging effects (Kim et al., 2004) . Such bacterial conversion and potential health consequences for the human host (Chiou et al., 2014) are hardly unique: Baicalin, puerarin, and daidzin, which are widely found in TCM prescriptions, can also be metabolized by gut microbiome (Kim et al., 1998) . keywords: bacteria; cancer; chinese; crc; disease; drug; effects; et al; flora; gut; gut microbiome; health; host; human; intestinal; medicine; metabolism; mice; microbial; microbiome; research; studies; tcm; treatment cache: cord-024111-7yrftdp4.txt plain text: cord-024111-7yrftdp4.txt item: #55 of 161 id: cord-024629-5q7abusm author: Luna, Beatriz title: Considerations when Characterizing Adolescent Neurocognitive Development date: 2020-05-11 words: 1273 flesch: 10 summary: When the aim is to model subject-specific developmental trajectories, as in the neurodevelopment of individual differences, a single cohort design is optimal, but with consideration to confounding non-developmental visit effects. Alternatively, group-level normative developmental changes and their physiological underpinnings may be better suited by an accelerated longitudinal design that can control for non-developmental visit effects. keywords: adolescence; age; data; development; effects cache: cord-024629-5q7abusm.txt plain text: cord-024629-5q7abusm.txt item: #56 of 161 id: cord-025170-dtbm4ue1 author: Malbrain, Manu L. N. G. title: Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA) date: 2020-05-24 words: 9185 flesch: 34 summary: Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis Intravenous balanced solutions: from physiology to clinical evidence It is time to consider the four D's of fluid management Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults Resuscitation fluids National Institute for H, Care Excellence Guideline Development G. Intravenous fluid therapy for adults in hospital: summary of NICE guidance Intravenous fluid therapy for hospitalized and critically ill children: rationale, available drugs and possible side effects Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting adult volunteers Maintenance intravenous fluids in acutely ill patients Maintenance fluid therapy and fluid creep impose more significant fluid, sodium, and chloride burdens than resuscitation fluids in critically ill patients: a retrospective study in a tertiary mixed ICU population Normal saline to dilute parenteral drugs and to keep catheters open is a major and preventable source of hypernatremia acquired in the intensive care unit Mortality after fluid bolus in African children with severe infection Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice Independent and dependent variables of acid-base control Stewartìs textbook of acid-base Lulucom Electrolyte shifts across the artificial lung in patients on extracorporeal membrane oxygenation: interdependence between partial pressure of carbon dioxide and strong ion difference Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilution Effects of intravenous solutions on acid-base equilibrium: from crystalloids to colloids and blood components In vivo conditioning of acid-base equilibrium by crystalloid solutions: an experimental study on pigs Resuscitation fluids are used to correct an intravascular volume deficit or acute hypovolemia; replacement solutions are prescribed to correct existing or developing deficits that cannot be compensated by oral intake alone keywords: administration; albumin; balance; care; crystalloids; fluid; intravenous; patients; pressure; renal; resuscitation; shock; solutions; surgery; therapy; trial; volume cache: cord-025170-dtbm4ue1.txt plain text: cord-025170-dtbm4ue1.txt item: #57 of 161 id: cord-026028-qj290zu6 author: None title: Spezielle Arzneimitteltherapie in der Schwangerschaft date: 2008-12-10 words: 80043 flesch: 38 summary: Eine spätere prospektive Untersuchung derselben Autorengruppe findet auch bei jenen Kindern, deren Mütter während der gesamten Schwangerschaft Trizyklika (46 Mutter-Kind-Paare; davon 36 bereits in der Studie von 1997 erfasst) genommen hatten, keine arzneispezifischen Auffälligkeiten in der Entwicklung der Kinder Unterschiede in der Entwicklung der Kinder bis zum 1. keywords: 100; 2000; 2003; 2005; aber; abschnitt; acid; acute; allerdings; als; als bei; alter; analysis; anderen; anomalies; anwendung; anwendung von; applikation; auch; auch als; auch bei; auch die; auch eine; auch für; auf; auf das; auf den; auf die; auf eine; auf teratogene; auffälligkeiten; aufgrund; aus; aus der; auswirkungen; auswirkungen auf; autoren; außerdem; b. bei; behandelt; behandelt werden; behandlung; behandlung mit; behandlung von; bei anderen; bei denen; bei der; bei einer; bei frauen; bei kindern; bei neugeborenen; bei nicht; bei schwangeren; bei über; beiden; beim; bekannt; beobachtet; berichtet; beschreibt; beschrieben; besonders; bestätigt; birth; bis; bis zu; bisher; bisher keine; bisher nicht; blut; bzw; cancer; case; chemotherapy; children; control; dabei; daher; das; das mit; das risiko; dass; dass die; dass eine; daten; davon; defects; dem; den fetus; denen; der; der behandlung; der fetalen; der geburt; der mutter; der mütterlichen; der schwangerschaft; der therapie; der wahl; des; development; diabetes; diagnostik; die; die als; die anwendung; die konzentration; die mit; die nicht; die von; die zur; diese; disease; diskutiert; dosen; dosis; drugs; durch; durch die; ebenfalls; effects; effekte; eigenschaften; ein kind; eine; eine andere; eine differenzierte; eine erhöhte; einer der; einer studie; einer therapie; eingenommen; eingesetzt; eingesetzt werden; einige; einnahme; empfehlung für; entwicklung; entwicklung der; erfahrungen; erfahrungen mit; erhöhtes; ersten; es bisher; es ist; es keine; es nach; es nicht; es sich; es wird; es wurde; es zu; etwa; exponierten; exposition; exposition mit; exposure; fall; fallberichte; fanden; fanden sich; fehlbildungen; fehlbildungen auf; fehlbildungsrisiko; fetal; fetalen; feten; fetus; frauen; frauen mit; fällen; führen; führt; für; für das; für den; für die; für eine; gabe; gabe von; gegenüber; gehören; gibt; gibt es; gilt; gruppe; gut; haben; hat; hat sich; hatte; heute; hinweise auf; human; häufiger; indikation; infant; insbesondere; insgesamt; insulin; intrauterine; invasive; ist; ist als; ist auch; ist bei; ist das; ist der; ist die; ist ein; ist für; ist mit; ist nicht; jahren; jedoch; jedoch nicht; kann; kann bei; kann die; kapitel; keine erfahrungen; keine fehlbildungen; keine für; keine hinweise; keinen; kind mit; kinder; kindern mit; kindern von; kombination mit; konnte; kontrollgruppe; konzentration; källén; können; liegen; liegen keine; malformations; man; maternal; mehr; menschen; mit; mit anderen; mit der; mit einer; mit g; mit oder; mittel; muss; muss eine; muss mit; mutter mit; mutter und; möglich; mütter; mütterlichen; nach; nach behandlung; nach der; nach einer; nebenwirkungen; neonatal; neugeborenen; nicht; nicht als; nicht auf; nicht beobachtet; nicht für; nicht mit; nicht nur; nicht vor; nicht zu; noch; noch bei; noch nicht; nur; nur bei; oder; oder zur; ohne; oral; pharmakologie und; plazenta; population; potenzial; praxis; pregnancy; pregnancy outcome; pregnancy pregnancy; prenatal; prospektiv; rate; rechtfertigt; report; retrospektiven; review; risiko; risiko für; risiko von; risikobegründeten; risikobewertung; risk; safety; schwangeren; schwangerschaft nicht; schwangerschaft wird; schwangerschaften; schwangerschaftsabbruch; schwangerschaftswoche; sehr; sein; seit; sich; sich bei; sich ein; sich mit; siehe; siehe auch; signifikant; sind; sind bei; sind keine; sind nicht; smoking; sollte; sollte die; sowie; sowie bei; sowohl; spontanabort; studie; studie mit; study; stunden; störungen; substanzen; symptome; syndrome; tag; tage; teratogene; teratogenität; therapie; therapie mit; therapie von; treatment; trimenon; trimenon keine; trimenon mit; trimester; täglich; und; und andere; und auf; und bei; und das; und der; und eine; und ist; und kann; und mit; und mitarbeiter; und nach; und toxikologie; und wird; und zu; unter; unter den; untersucht; untersuchungen; use; utero; vergleich; vitamin; vom; von; von anderen; von der; von einer; von g; vor; waren; weder; wegen; wegen der; weitere; wenn; wenn die; werden; werden die; werden kann; werden nach; werden und; wie; wie bei; wie eine; wie z.; wiesen; wird; wird auch; wird bei; wird der; wird ein; wird mit; wird von; wirkt; wirkung; woche; women; wurde; wurde eine; wurde mit; wurde nicht; wurde von; wurden bei; während; während der; z. b.; zeigten; zu den; zu einer; zum; zur; zur anwendung; zur therapie; zusammenhang mit; zwar; zwei; zwischen; über; über den; über die; über eine; übersicht; übersicht bei cache: cord-026028-qj290zu6.txt plain text: cord-026028-qj290zu6.txt item: #58 of 161 id: cord-026490-9xg8v6h5 author: Beikzadeh, Samira title: The Effects of Novel Thermal and Nonthermal Technologies on the Properties of Edible Food Packaging date: 2020-06-09 words: 7923 flesch: 41 summary: Ultrasound treatment improved film properties with the increase in sonicated duration time, and decreased WVP and film moisture absorption in sample via 60-min sonication. Apple peel-based edible film development using a high-pressure homogenization High pressure homogenization of mechanically deboned chicken meat protein suspensions to improve mechanical and barrier properties of edible films Nonthermal plasma-a tool for decontamination and disinfection Physical modification of starch by high-pressure homogenization for improving functional properties of κ-carrageenan/starch blend film Functional, thermal, and antimicrobial properties of soluble soybean polysaccharide biocomposites reinforced by nano TiO2 Advanced synthesis of materials for intermediate-temperature solid oxide fuel cells Physicochemical characterization of argon plasma-treated starch film Hexamethyldisiloxane cold plasma treatment and amylose content determine the structural, barrier and mechanical properties of starch-based films Effect of highpressure homogenization on particle size and film properties of soy protein isolate Effect of high pressure on the physical properties of barley starch Effect of ultrasound treatment on properties of soy proteins film Sodium chloride levels in comminuted chicken muscle in relation to processing characteristics and Fresnel reflectance detected with a polarimetric probe Effects of combined treatments of irradiation and antimicrobial coatings on reduction of food pathogens in broccoli florets Microwave heating in food processing Cold plasma treatment for fresh-cut melon stabilization Biopolymer interactions affect the functional properties of edible films based on agar, cassava starch and arabinoxylan blends Understanding high pressureinduced changes in wheat flour-water suspensions using starchgluten mixtures as model systems Natural-based plasticizers and biopolymer films: A review High pressure-induced tapioca starch gels: physico-chemical characterization and stability Development of bioactive coatings based on γ-irradiated proteins to preserve strawberries Effect of high-pressure homogenization on the structure and thermal properties of maize starch Effect of highpressure homogenization on microstructure and rheological properties of alkali-treated high-amylose maize starch The effects of ultrasonic/microwave assisted treatment on the properties of soy protein isolate/microcrystalline wheat-bran cellulose film The effects of ultrasonic/microwave assisted treatment on the properties of soy protein isolate/titanium dioxide films The effects of ultrasonic/microwave assisted treatment on the water vapor barrier properties of soybean protein isolate-based oleic acid/stearic acid blend edible films Report of a Joint FAO/IAEA/WHO Expert Committee Effect of ultraviolet irradiation combined with chitosan coating on preservation of jujube under ambient temperature Effects of ultrasound treatment on lipid self-association and properties of methylcellulose/stearic acid blending films Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations keywords: acid; coating; effect; films; food; irradiation; microwave; min; packaging; plasma; pressure; properties; protein; starch; treatment; ultrasound cache: cord-026490-9xg8v6h5.txt plain text: cord-026490-9xg8v6h5.txt item: #59 of 161 id: cord-030027-273pjajl author: Moriconi, Eleonora title: Neuroendocrine and Metabolic Effects of Low-Calorie and Non-Calorie Sweeteners date: 2020-07-16 words: 11349 flesch: 31 summary: These results suggested that non-calorie sweeteners consumption during pregnancy could impact on offspring adipose tissue differentiation, promoting childhood obesity (217) . Low calorie and non-calorie sweeteners provide no or few calories and are characterized by a high sweetness taste. keywords: calorie; consumption; diabetes; effects; energy; food; glucose; gut; health; human; intake; metabolic; microbiota; non; obesity; saccharin; studies; sucralose; sugar; sweeteners; taste; use; weight cache: cord-030027-273pjajl.txt plain text: cord-030027-273pjajl.txt item: #60 of 161 id: cord-030909-6if3qquj author: None title: Perspectives on the Economics of the Environment in the Shadow of Coronavirus date: 2020-08-27 words: 28261 flesch: 43 summary: The economic crisis can end up having long-run negative consequences for the environment if, as a result, regulations and environmental policies are relaxed or if institutions are weakened. Acceptability of environmental policies by companies is a necessary condition for their implementation. keywords: air; carbon; case; change; climate; climate change; companies; conditions; consumption; countries; covid-19; covid-19 pandemic; crisis; data; demand; economy; effects; emissions; energy; environmental; et al; european; example; food; global; green; health; impact; increase; measures; need; new; pandemic; period; policies; policy; public; recovery; research; resource; supply; term; time; use; world cache: cord-030909-6if3qquj.txt plain text: cord-030909-6if3qquj.txt item: #61 of 161 id: cord-032546-7786vr0y author: Guo, Siyu title: Comparative Efficacy of Danshen Class Injections for Treating Acute Coronary Syndrome: A Multidimensional Bayesian Network Meta-Analysis of Randomized Controlled Trials date: 2020-08-26 words: 6420 flesch: 38 summary: Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables 2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines A clustering technique for summarizing multivariate data Fibrinogen in relation to degree and composition of coronary plaque on intravascular ultrasound in patients undergoing coronary angiography Effect of Danhong injection on plasma endothelin and C-reactive protein in patients with acute coronary syndrome The effect of Danhong injection in hemorheology in old patients with acute coronary syndrome Serum biomarkers and source of inflammation in acute coronary syndromes and percutaneous coronary interventions Graphical tools for network meta-analysis in STATA Clinical research on treating acute coronary syndrome by Danhong injection Clinical observation of Danhong injection in the treatment of senile acute coronary syndrome. China Health Ind Clinical observation of Danhong injection in the treatment of acute coronary syndrome The role of inflammation in acute coronary syndromes: review of the literature Restenosis: delineating the numerous causes of drug-eluting stent restenosis Effect of Danhong injection and atorvastatin on the levels of circulating IL -6, sCD40L and APN in acute coronary syndrome Neuroprotective Effect of Danhong Injection on Cerebral Ischemia-Reperfusion Injury in Rats by Activation of the PI3K-Akt Pathway keywords: acute; analysis; chis; clinical; danhong; danshen; effect; injection; patients; syndrome; treatment cache: cord-032546-7786vr0y.txt plain text: cord-032546-7786vr0y.txt item: #62 of 161 id: cord-033334-p7szd86k author: Mann, Jaclyn Kelly title: The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19 date: 2020-10-08 words: 7291 flesch: 23 summary: Peptides in ovotransferrin that have high sequence homology with these bovine lactoferrin and human lactoferrin peptides acting against herpes simplex virus, human cytomegalovirus and adenovirus, were shown to have double the antiviral activity compared with the bovine lactoferrin peptides [72] . Damage of the outer membrane of enteric gram negative bacteria by lactoferrin and transferrin The antifungal activity of lactoferrin and its derived peptides: mechanisms of action and synergy with drugs against fungal pathogens Lactoferrin as a natural immune modulator Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males Lactoferrin accelerates reconstitution of the humoral and cellular immune response during chemotherapy-induced immunosuppression and bone marrow transplant in mice Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages Lactoferrin in a context of inflammation-induced pathology Lactoferrin suppresses neutrophil extracellular traps release in inflammation Antihypertensive effects of lactoferrin hydrolyzates: inhibition of angiotensin-and endothelin-converting enzymes Lactoferrin, ovotransferrin & lysozyme in COVID-19 Review Aerosolized bovine lactoferrin counteracts infection, inflammation and iron dysbalance in a cystic fibrosis mouse model of Pseudomonas aeruginosa chronic lung infection Peptides affecting coagulation Antiviral activity of ovotransferrin derived peptides Ovotransferrin peptides that are conserved with peptides from bovine lactoferrin (which are also active against herpes simplex virus) were shown to be more potent than bovine lactoferrin peptides in their effect against Marek's disease virus Antiviral effect of ovotransferrin in mouse peritoneal macrophages by up-regulating type keywords: activity; bovine; covid-19; disease; effect; egg; human; immune; inflammation; iron; lactoferrin; lysozyme; ovotransferrin; peptides; sars; white cache: cord-033334-p7szd86k.txt plain text: cord-033334-p7szd86k.txt item: #63 of 161 id: cord-033736-bsmqqi6j author: Bajraktari, Saranda title: Health-promoting and preventive interventions for community-dwelling older people published from inception to 2019: a scoping review to guide decision making in a Swedish municipality context date: 2020-10-14 words: 10551 flesch: 37 summary: To summarise intervention effects, we classified health outcomes in broader categories (Table 3) . However, these findings on long-term effects are in contrast to a previous PHV trial that indicated that intervention effects remained only for as long as the home visits were ongoing [111] , and thus, highlights the importance of long term follow-ups over. keywords: community; cost; dwelling; effects; exercise; group; health; home; interventions; people; prevention; review; studies; study; trial cache: cord-033736-bsmqqi6j.txt plain text: cord-033736-bsmqqi6j.txt item: #64 of 161 id: cord-102595-3lbrfsrh author: Adam, Kirsten C.S. title: Steady-state visually evoked potentials and feature-based attention: Pre-registered null results and a focused review of methodological considerations date: 2020-10-13 words: 9079 flesch: 42 summary: To further understand the lack of SSVEP attention effect, we performed additional non-pre-430 registered control analyses. We likewise found null attention effects when 573 analyzing only accurate trials ( Figure S11) . keywords: attend; attention; color; cue; effect; feature; frequency; participants; ssvep; target; task; trial cache: cord-102595-3lbrfsrh.txt plain text: cord-102595-3lbrfsrh.txt item: #65 of 161 id: cord-143246-f97v2cih author: Paul, Aneesh Mathews title: Multifaceted COVID-19 Outbreak date: 2020-08-26 words: 6065 flesch: 58 summary: Contesting Religion in Secularized Western European Countries India: Infections, Islamophobia, and Intensifying Societal Polarization New Center for Public Integrity/Ipsos Poll finds most Americans say the Coronavirus Pandemic is a Natural Disaster StatCa of Increase in Anti-Asian Sentiment, Attacks COVID-19 and Religious Congregations: Implications for Spread of Novel Pathogens Religion and the COVID-19 Pandemic God and COVID-19 Public Health Response to the Initiation and Spread of Pandemic COVID-19 in the United States High COVID-19 Attack Rate Among Attendees at Events at a Church-Arkansas Have Prayers Changed in Lockdown? A lot of literature exists in COVID-19, but most of them talk about the social and psychological side of the COVID problems. keywords: countries; covid-19; education; effects; home; india; learning; life; lockdown; pandemic; people; students; system; world cache: cord-143246-f97v2cih.txt plain text: cord-143246-f97v2cih.txt item: #66 of 161 id: cord-193947-vcm3v0ix author: Pollmann, Michael title: Causal Inference for Spatial Treatments date: 2020-10-31 words: 27980 flesch: 42 summary: They have an attractive quasi-experimental interpretation and are valid by design if the choice of treatment location is as good as random within a set of plausible candidate locations. Instead, I recommend estimators that are formally valid under the quasi-experimental variation in treatment location sometimes used to informally justify the assumptions of the difference-in-differences approach. keywords: assumption; average; candidate locations; candidate treatment; control; data; distance; grocery; individuals; number; outcomes; paper; region; ring; store; treatment assignment; treatment effects; treatment locations; treatments; variance; â � cache: cord-193947-vcm3v0ix.txt plain text: cord-193947-vcm3v0ix.txt item: #67 of 161 id: cord-252855-xtsnlu1f author: Drago-Serrano, Maria Elisa title: Lactoferrin: Balancing Ups and Downs of Inflammation Due to Microbial Infections date: 2017-03-01 words: 12051 flesch: 25 summary: Therefore, all findings on Lf activities suggest that Lf and Lfcins can be of potential use as antimicrobial and anti-inflammatory compounds, either alone or as adjuncts to conventional antibiotics and drugs. The reason for the lack of bLf protecting effect in these viral infection mice models is unknown, but possible explanations could be related to timing, dosing, and route of bLf administration. keywords: action; activity; blf; bovine; cells; coli; cytokines; effects; hlf; human; infection; inflammation; iron; lactoferrin; levels; lps; mice; milk; model; response; role; tnfα cache: cord-252855-xtsnlu1f.txt plain text: cord-252855-xtsnlu1f.txt item: #68 of 161 id: cord-253000-nwbmxepi author: Margină, Denisa title: Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors date: 2020-06-10 words: 8289 flesch: 25 summary: Studies on animal models show an improvement in neurodegenerative diseases after fasting, while other studies prove that intermittent fasting diets boost the levels of antioxidant defense, neurotrophic factors (BDNFS, H-70 and FGF2), proteins involved in adaptive response (HSP-70 and GRP-78), and reduce pro-inflammatory cytokines levels (TNFa, IL-1β, and IL-6) SCFAs have anti-inflammatory effects that bind to the nuclear transcription factor PPARγ (peroxisome proliferator-activated receptor γ) and, consequently, inhibit the NF-kB pathway keywords: body; cells; changes; day; diet; diseases; effects; fasting; gut; health; inflammation; insulin; intermittent; metabolic; obese; risk; studies; study; weight cache: cord-253000-nwbmxepi.txt plain text: cord-253000-nwbmxepi.txt item: #69 of 161 id: cord-253251-i79h14f7 author: Kandala, Ngianga-Bakwin title: An investigation of district spatial variations of childhood diarrhoea and fever morbidity in Malawi date: 2005-09-01 words: 6527 flesch: 45 summary: The influence of mother's age on child diarrhoea and fever show a general tendency for child morbidity to decline with increasing maternal age. Demographic and health surveys, comparative studies no Maternal education and child survival: A comparative study of survey data from 17 countries Diarrhoeal diseases and child morbidity and mortality Infant and child mortality: Development, environment, and custom Investigating child mortality in Malawi using family and community random effects: A Bayesian analysis BayesX-software for Bayesian inference based on Markov chain Monte Carlo simulation techniques Child survival in big cities: Are the poor disadvantaged? keywords: age; child; diarrhoea; district; effects; fever; health; malawi; morbidity; mortality; prevalence; risk cache: cord-253251-i79h14f7.txt plain text: cord-253251-i79h14f7.txt item: #70 of 161 id: cord-256838-8rzibpbl author: Eng, Yi Shin title: Unraveling the Molecular Mechanism of Traditional Chinese Medicine: Formulas Against Acute Airway Viral Infections as Examples date: 2019-09-27 words: 9254 flesch: 34 summary: From the viewpoint of pathophysiology, TCM formulas used to manage airway viral infections need to have antiviral activity against such viruses listed above, and/or to induce antiviral cytokines, and/or anti-inflammatory effect, and/or to relieve symptoms commonly presented in airway infections ( Figure 1 ). The ABC Clinical Guide to Herbs Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey Trends in the use of complementary health approaches among adults: United States Complementary and alternative medicine use among adults and children: United States Current state of phytotherapy in Germany Glycyrrhizic acid inhibits virus growth and inactivates virus particles Antiviral effect of cimicifugin from Cimicifuga foetida against human respiratory syncytial virus Pterodontic Acid Isolated from Laggera pterodonta Inhibits Viral Replication and Inflammation Induced by Influenza A Virus A possible mechanism of interstitial pneumonia during interferon therapy with sho-saiko-to A case of acute eosinophilic pneumonia due to Sho-saiko-to Autoimmune hepatitis with drug-induced pneumonia due to Sho-saiko-to Two cases of pneumonia caused by Sho-saiko-to Acute lymphoblastic leukemia complicated by type C hepatitis during treatment and further by acute interstitial pneumonia due to sho-saiko-to in 7-year-old An autopsy case of interstitial pneumonia probably induced by Sho-saiko-to A case of interstitial pneumonia with chronic hepatitis C following interferon-alfa and sho-saiko-to therapy A comparative study on anticoagulant activities of three Chinese herbal medicines from the genus Panax and anticoagulant activities of ginsenosides Rg1 and Rg2 Brief communication: American ginseng reduces warfarin's effect in healthy patients: A randomized Thrombosis of a prosthetic aortic valve disclosing a hazardous interaction between warfarin and a commercial ginseng product Ginseng and vaginal bleeding Ginseng face cream and unexplained vaginal bleeding Interaction between warfarin and Panax ginseng in ischemic stroke patients Systems biology: Metabonomics Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: As pillars of the bridge between Chinese and Western medicine Application of metabolomics on diagnosis and treatment of patients with psoriasis in traditional Chinese medicine Biomarkers of primary dysmenorrhea and herbal formula intervention: An exploratory metabonomics study of blood plasma and urine Plasma metabolic profiling of normal and dysmenorrhea syndrome rats and the effects of Xiang-Fu-Si-Wu Decoction intervention Adulterants in Asian patent medicines Heavy metal content of ayurvedic herbal medicine products Arsenic and mercury intoxication due to Indian ethnic remedies Lead, mercury, and arsenic in US-and Indian-manufactured Ayurvedic medicines sold via the Internet Risk factors for adverse drug events among nursing home residents Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats Herb-drug interactions between Scutellariae Radix and mefenamic acid: Simultaneous investigation of pharmacokinetics, anti-inflammatory effect and gastric damage in rats The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1 Baicalin in radical scavenging and its synergistic effect with beta-carotene in antilipoxidation Studies on the competitive binding of cleviprex and flavonoids to plasma protein by multi-spectroscopic methods: A prediction of food-drug interaction Spectroscopic investigation on the food components-drug interaction: The influence of flavonoids on the affinity of nifedipine to human serum albumin The increased binding affinity of curcumin with human serum albumin in the presence of rutin and baicalin: A potential for drug delivery system Interaction of baicalin with berberine for glucose uptake in 3T3-L1 adipocytes and HepG2 hepatocytes Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs? keywords: activities; activity; anti; drug; effects; formulas; herbal; herbs; influenza; interactions; mechanisms; medicine; molecules; patients; tang; tcm; use; virus cache: cord-256838-8rzibpbl.txt plain text: cord-256838-8rzibpbl.txt item: #71 of 161 id: cord-256881-7sejcqda author: Heindel, Jerrold J. title: Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies date: 2020-07-16 words: 24801 flesch: 42 summary: To address this critical gap, the present report represents a synthesis and integration of the results of 8 of the 14 independent studies by principal investigators willing to participate in an effort to coalesce the findings and assess patterns of BPA exposures across the various end organs examined in the same animal cohorts and, frequently, in the same animals. Collectively, the results provide unbiased evidence that BPA exposures at human-relevant doses result in adverse effects on the rat prostate gland. keywords: animals; bisphenol; bpa; bpa exposure; bpa studies; bpa study; clarity; data; day bpa; dose; dose bpa; effects; exposure; expression; female; gland; heart; hormone; low; males; mammary; mice; pnd; prostate; rats; results; studies; study; μg bpa cache: cord-256881-7sejcqda.txt plain text: cord-256881-7sejcqda.txt item: #72 of 161 id: cord-256992-rwy0n01l author: Taheri, Yasaman title: Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications date: 2020-08-01 words: 7288 flesch: 31 summary: Myricetin antidiabetic activity has been reported by several authors in the last few years and limited reports are also available on its anti-obesity activity but in this review, we focused on only its antidiabetic potential. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials. keywords: activities; activity; antioxidant; cancer; cells; compound; effects; flavonoids; glucose; human; inhibition; model; myricetin; potential; rats; studies; study; vitro; vivo cache: cord-256992-rwy0n01l.txt plain text: cord-256992-rwy0n01l.txt item: #73 of 161 id: cord-257167-rz4r5sj7 author: None title: Abstracts for the 29th Annual Meeting of the Japan Neuroscience Society (Neuroscience2006) date: 2006-12-31 words: 241480 flesch: 43 summary: Inst., Kyoto Univ., Inuyama, Japan GABAergic cells in the cerebral cortex are divided into subgroups: parvalbumin (PV)-, somatostatin (SOM)-, calretinin (CR)-, and calbindin-containing types. In the present study, we therefore investigated the synthesis of sex steroids and corticosteroids in the hippocampus of adult male rats, by monitoring the metabolism of tritiated steroids with HPLC system. PS2A-G125 GABA depolarizes GnRH neurons isolated from adult GnRH-EGFP transgenic rats Chengzhu Yin, Nobuyuki Tanaka, Masakatsu Kato, Yasuo Sakuma Nippon Medical School, Department of physiology, Tokyo, Japan GnRH neurons are essential in the reproductive neuroendocrine system. keywords: 1,2; 100; acid; action; activation; activities; activity; addition; administration; adult; age; amplitude; amygdala; analysis; animals; antagonist; application; area; astrocytes; auditory; axons; bdnf; behavioral; binding; biology; body; brain; brain activity; brain development; brain function; brain research; brain science; bsi; ca1; calcium; camkii; cells; cellular; center; central; cerebellar; cerebral; changes; channel; chiba; cns; cognitive; complex; condition; contrast; control; correlation; cortex; cortex neurons; cortical; crest; cultured; current; data; days; death; decrease; dendrites; dendritic; department; dept; development; difference; differentiation; direction; disease; disorders; distribution; div; division; domain; dopamine; dopaminergic; dorsal; dynamics; effect; estrogen; evoked; excitatory; experiments; exposure; expression; eye; factors; family; fibers; field; findings; firing; fmri; following; formation; fos; frequency; function; funds; gaba; gabaergic; gene; gene expression; gfp; glutamate; gnrh neurons; graduate; granule; group; growth; gyrus; hand; health; high; hippocampal neurons; hippocampus; hiroshi; human; imaging; increase; individual; induced; induction; inhibition; inhibitory; injection; injury; inputs; institute; interaction; interneurons; intracellular; involvement; japan; japan brain; japan neural; japan neurons; japan science; jst; kakenhi; kinase; kyoto; kyoto university; lab; laboratory; layer; learning; left; level; life; like; localization; loss; ltd; ltp; male; manner; mechanisms; med; medical; medicine; membrane; memory; method; mice; microglia; migration; model; molecular; molecules; monkeys; motion; motor; motor neurons; mouse; mouse brain; movement; mrna; multiple; muscle; mutant; nagoya; national; nerve; nervous; network; neural; neurite; neuronal; neurons; neuroscience; new; nmda; non; novel; nuclei; nucleus; number; olfactory; onset; order; osaka; osaka university; pain; pathway; patients; pattern; period; phase; phosphorylation; physiology; plasticity; play; postnatal; postsynaptic; potential; prefrontal; presence; present; presynaptic; primary; process; processes; processing; progenitor cells; projection neurons; proliferation; properties; protein; ps2p; ps3a; ps3p; purkinje cells; pyramidal; rat brain; rate; rats; receptor; recorded; recording; reduced; region; regulation; relationship; release; report; required; research; research funds; research institute; response; results; reward; right; riken; role; saitama; school; sciences; second; selective; sensory; signaling; signals; site; size; slices; social; specific; spike; spinal; spines; state; stem cells; stimulation; stimuli; stimulus; stress; structure; studies; study; subjects; surface; synapses; synaptic; system; target; task; technology; temporal; term; terminals; test; time; tohoku; tokyo; tokyo university; transcription; transgenic; transmission; treatment; tsukuba; type; university; university graduate; university school; usa; visual; vitro; vivo; voltage; weeks; wild; zone cache: cord-257167-rz4r5sj7.txt plain text: cord-257167-rz4r5sj7.txt item: #74 of 161 id: cord-257197-i9bucuma author: Natarajan, Pavithra title: Understanding the influence of experimental factors on bio-interactions of nanoparticles: Towards improving correlation between in vitro and in vivo studies date: 2020-09-21 words: 6580 flesch: 30 summary: Frontiers in Chemistry Poly(ethylene glycol)-lipid conjugates regulate the calciuminduced fusion of liposomes composed of phosphatidylethanolamine and phosphatidylserine Silicon Quantum Dots Metal-Enhanced Photoluminescence by Gold Nanoparticles in Colloidal Ensembles: Effect of Surface Coating Cell-Penetrating Peptide-Modified Gold Nanoparticles for the Delivery of Doxorubicin to Brain Metastatic Breast Cancer Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis Penetratin Peptide-Functionalized Gold Nanostars: Enhanced BBB Permeability and NIR Photothermal Treatment of Alzheimer's Disease Using Ultralow Irradiance Biocompatible Peptide-Coated Ultrasmall Superparamagnetic Iron Oxide Nanoparticles for In Vivo Contrast-Enhanced Magnetic Resonance Imaging A Study of the Cellular Uptake of Magnetic Branched Amphiphilic Peptide Capsules Protein coated gold nanoparticles as template for the directed synthesis of highly fluorescent gold nanoclusters Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine Multiresponsive albumin-lonidamine conjugated hybridized gold nanoparticle as a combined photothermal-chemotherapy for synergistic tumor ablation Acquired Resistance to Antibody-Drug Conjugates Anti-HER2 antibody and ScFvEGFR-conjugated antifouling magnetic iron oxide nanoparticles for targeting and magnetic resonance imaging of breast cancer Impact of conjugation strategies for targeting of antibodies in gold nanoparticles for ultrasensitive detection of 17 beta-estradiol Click Chemistry Immobilization of Antibodies on Polymer Coated Gold Nanoparticles A novel immuno-gold labeling protocol for nanobody-based detection of HER2 in breast cancer cells using immuno-electron microscopy Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: Applications in oral cancer DNA-Grafted Poly(acrylic acid) for One-Step DNA Functionalization of Iron Oxide Nanoparticles Binding of single stranded nucleic acids to cationic ligand functionalized gold nanoparticles Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells Superparamagnetic iron oxide nanoparticles functionalized by peptide nucleic acids Nucleic acid and nucleotide-mediated synthesis of inorganic nanoparticles Gold Nanoparticle-Aptamer-Based LSPR Sensing of Ochratoxin A at a Widened Detection Range by Double Calibration Curve Method Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors Disposable aptamer-sensor aided by magnetic nanoparticle enrichment for detection of salivary cortisol variations in obstructive sleep apnea patients Dose-, treatment-and time-dependent toxicity of superparamagnetic iron oxide nanoparticles on primary rat hepatocytes Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies Gold nanoparticles: Distribution, bioaccumulation and toxicity. An Evaluation of their Relaxometric and Magnetic Hyperthermia Properties Have Nanoscience and Nanotechnology Delivered? Progress towards standardized and validated characterizations for measuring physicochemical properties of manufactured nanomaterials relevant to nano health and safety risks Synthesis, characterization, applications, and challenges of iron oxide nanoparticles Size-Controlled Synthesis of Sub-10-nanometer Citrate-Stabilized Gold Nanoparticles and Related Optical Properties Digestive ripening, nanophase segregation and superlattice formation in gold nanocrystal colloids Optimal Design and Characterization of Superparamagnetic Iron Oxide Nanoparticles Coated with Polyvinyl Alcohol for Targeted Delivery and Imaging Synthesis and characterization of nanometer-size Fe3O4 and gamma-Fe2O3 particles Quantitative Measurement of Ligand Exchange with Small-Molecule Ligands on Iron Oxide Nanoparticles via Radioanalytical Techniques Current trends in using polymer coated gold nanoparticles for cancer therapy Facile and General Method for Synthesis of Sugar Coated Gold Nanoparticles Hydroxide assisted synthesis of monodisperse and biocompatible gold nanoparticles with dextran A simple and efficient method for polymer coating of iron oxide nanoparticles Colloidal Stability of Gold Nanoparticles Modified with Thiol Compounds: Bioconjugation and Application in Cancer Cell Imaging Synthesis and characterization of superparamagnetic iron oxide nanoparticles as calcium-responsive MRI contrast agents Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine Approved Drug Products with Therapeutic Equivalence Evaluations Understanding the Nano-bio Interfaces: Lipid-Coatings for Inorganic Nanoparticles as Promising Strategy for Biomedical Applications. keywords: cell; coated; delivery; gold; iron; nanoparticles; nps; oxide; r n; studies; surface; toxicity; u r; uptake; vivo cache: cord-257197-i9bucuma.txt plain text: cord-257197-i9bucuma.txt item: #75 of 161 id: cord-257514-gw9xnb4x author: Yang, Mengling title: Hydrogen: A Novel Option in Human Disease Treatment date: 2020-09-05 words: 10464 flesch: 28 summary: DSM 2243 T Therapeutic roles of carbon monoxide in intestinal ischemia-reperfusion injury MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline The effects of hydrogenrich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats The effects of hydrogen-rich saline solution on intestinal anastomosis performed after intestinal ischemia reperfusion injury Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice Hydrogen-rich saline regulates intestinal barrier dysfunction, dysbiosis, and bacterial translocation in a murine model of sepsis Hydrogen gas protects against intestinal injury in wild type but not NRF2 knockout mice 15 Oxidative Medicine and Cellular Longevity with severe sepsis by regulating HO-1 and HMGB1 release Hydrogen gas restores exhausted CD8 + T cells in patients with advanced colorectal cancer to improve prognosis Hydrogen metabolism inHelicobacter pyloriPlays a role in gastric carcinogenesis through facilitating CagA translocation The protective of hydrogen on stress-induced gastric ulceration Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: a new biological vision Hydrogen-rich saline attenuates acute hepatic injury in acute necrotizing pancreatitis by inhibiting inflammation and apoptosis, involving JNK and p38 mitogen-activated protein kinase-dependent reactive oxygen species Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway Effects of hydrogen gas inhalation on endometriosis in rats Protective effect of hydrogen rich saline solution on experimental ovarian ischemia reperfusion model in rats Hydrogenrich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress Hydrogen-rich water exerting a protective effect on ovarian reserve function in a mouse model of immune premature ovarian failure induced by zona pellucida 3 Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats Protection by hydrogen against gamma ray-induced testicular damage in rats Combination of Korean red ginseng extract and hydrogenrich water improves spermatogenesis and sperm motility in male mice Molecular hydrogen may enhance the production of testosterone hormone in male infertility through hormone signal modulation and redox balance Protective effects of hydrogen against low-dose long-term radiation-induced damage to the behavioral performances, hematopoietic system, genital system, and splenic lymphocytes in mice Saturated hydrogen alleviates CCl4-induced acute kidney injury via JAK2/STAT3/p65 signaling Aerosol inhalation of a hydrogen-rich solution restored septic renal function Hydrogen-rich saline alleviates kidney fibrosis following AKI and retains klotho expression Hydrogen-rich saline attenuates acute kidney injury after liver transplantation via activating p53-mediated autophagy Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway Hydrogen rich water attenuates renal injury and fibrosis by regulation transforming growth factor-β induced Sirt1 Hydrogen-rich saline promotes the recovery of renal function after ischemia/reperfusion injury in rats via anti-apoptosis and anti-inflammation Preventive effect of hydrogen water on the development of detrusor overactivity in a rat model of bladder outlet obstruction Saturated hydrogen improves lipid metabolism disorders and dysbacteriosis induced by a high-fat diet Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes L-Arabinose elicits gut-derived hydrogen production and 16 Oxidative Medicine and Cellular Longevity ameliorates metabolic syndrome in C57BL/6J mice on highfat-diet Hydrogen gas production is associated with reduced interleukin-1β mRNA in peripheral blood after a single dose of acarbose in Japanese type 2 diabetic patients Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice Hydrogen attenuates allergic inflammation by reversing energy metabolic pathway switch Pilot study: effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in thoroughbred horses after racing exercise Involvement of neutrophil dynamics and function in exercise-induced muscle damage and delayed-onset muscle soreness: effect of hydrogen bath Protective effect of hydrogen gas inhalation on muscular damage using a mouse hindlimb ischemia-reperfusion injury model Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: a report of three cases Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species Molecular hydrogen effectively heals alkali-injured cornea via suppression of oxidative stress High throughput siRNA screening for chloropicrin and hydrogen fluoride-induced cornea epithelial cell injury Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stemlike cell differentiation Therapeutic efficacy of hydrogen-rich saline alone and in combination with PI3K inhibitor in non-small cell lung cancer A gallbladder carcinoma patient with pseudo-progressive remission after hydrogen inhalation Brain metastases completely disappear in non-small cell lung cancer using hydrogen gas inhalation: a case report Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice Hydrogen protects rats from dermatitis caused by local radiation Pathological findings of COVID-19 associated with acute respiratory distress syndrome Strategies for the prevention and management of coronavirus disease 2019 Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses Effect of shikonin on spinal cord injury in rats via regulation of HMGB1/TLR4/NF-kB signaling pathway Hydrogen-rich saline attenuates cardiac and hepatic injury in doxorubicin rat model by inhibiting inflammation and apoptosis Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement Hydrogen inhalation ameliorates ventilator-induced lung injury Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice Allergic airway inflammation induces migration of mast cell populations into the mouse airway Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice Hydrogen treatment protects mice against chronic pancreatitis by restoring regulatory T cells loss Inhalation of hydrogen gas elevates urinary 8-hydroxy-2′-deoxyguanine in Parkinson's disease Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats Hydrogen and oxygen mixture to improve cardiac dysfunction and myocardial pathological changes induced by intermittent hypoxia in rats Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases Beneficial biological effects and the underlying mechanisms of molecular hydrogen -comprehensive review of 321 original articles Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation Hydrogen gas inhalation attenuates seawater instillation-induced acute lung injury via the Nrf2 pathway in rabbits Therapeutic efficacy of molecular hydrogen: a new mechanistic insight Hydrogen gas attenuates myocardial ischemia reperfusion injury independent of postconditioning in rats by attenuating endoplasmic reticulum stress-induced autophagy Propofol inhibits parthanatos via ROS-ER-calcium-mitochondria signal pathway in vivo and vitro Inhalation of hydrogen of different concentrations ameliorates spinal cord injury in mice by protecting spinal cord neurons from apoptosis, oxidative injury and mitochondrial structure damages Neuroprotective effect of hydrogen-rich saline in global cerebral ischemia/reperfusion rats: up-regulated Tregs and down-regulated miR-21, miR-210 and NF-κB expression Loading MiR-210 in endothelial progenitor cells derived exosomes boosts their beneficial effects on hypoxia/reoxygeneation-injured human endothelial cells via protecting mitochondrial function MicroRNA-210 is upregulated in hypoxic cardiomyocytes through Akt-and p53-dependent pathways and exerts cytoprotective effects Pilot study of H 2 therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress Molecular hydrogen: new antioxidant and antiinflammatory therapy for rheumatoid arthritis and related diseases Open-label trial and randomized, double-blind, placebocontrolled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques Hydrogen-rich saline ameliorates allergic rhinitis by reversing the imbalance of Th1/Th2 and up-regulation of CD4+CD25+Foxp3+regulatory T cells, interleukin-10, and membrane-bound transforming growth factor-β in guinea pigs Immunological effect of hydrogen gas-hydrogen gas improves clinical outcomes of cancer patients Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress Effects of hydrogen-rich water on the PI3K/AKT signaling pathway in rats with myocardial 12 Oxidative Medicine and Cellular Longevity ischemia-reperfusion injury Attenuation of cardiac ischaemiareperfusion injury by treatment with hydrogen-rich water Saturated hydrogen saline attenuates endotoxin-induced lung dysfunction Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen-activated protein kinase-caspase-3 signaling pathway following cerebral ischemia-reperfusion injury Hydrogen gas inhibits lung cancer progression through targeting SMC3 Influence of hydrogenoccluding-silica on migration and apoptosis in human esophageal cells in vitro Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagydependent pathway Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner H 2 protects against lipopolysaccharide-induced cardiac dysfunction via blocking TLR4-mediated cytokines expression Atg7 deficiency intensifies inflammasome activation and pyroptosis in Pseudomonas Sepsis The endotoxin delivery protein HMGB1 mediates caspase-11-dependent lethality in sepsis Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels Pyroptosis and apoptosis pathways engage in bidirectional crosstalk in monocytes and macrophages Ferroptosis: an iron-dependent form of nonapoptotic cell death Disulfiram/copper induces antitumor activity against both nasopharyngeal cancer cells and cancer-associated fibroblasts through ROS/MAPK and ferroptosis pathways HMGB1 regulates erastininduced ferroptosis via RAS-JNK/p38 signaling in HL-60/NRAS Q61L cells Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells Activation of glutathione peroxidase 4 as a novel anti-inflammatory strategy Genomics of circadian rhythms in health and disease Microbiota diurnal rhythmicity programs host transcriptome oscillations keywords: autophagy; cancer; cells; damage; effects; expression; gas; hydrogen; inhalation; injury; ischemia; liver; lung; model; molecular; oxidative; rats; reperfusion; saline; stress; treatment; water cache: cord-257514-gw9xnb4x.txt plain text: cord-257514-gw9xnb4x.txt item: #76 of 161 id: cord-259744-r9j5yzfc author: McDonagh, Phillip title: Identification and characterisation of small molecule inhibitors of feline coronavirus replication date: 2014-12-05 words: 5644 flesch: 34 summary: Data analysis were conducted in GraphPad Prism, with the 50% inhibitory concentration (IC50) and 50% cytotoxic concentration (CC50) values calculated using the inbuilt non-linear curve fitting functions following log 10 transformation of compound concentrations. For all tested compounds CPE inhibition remained greater than 50% when compounds were added at the latest tested time point of 6 h postinfection. keywords: assays; cells; chloroquine; compounds; cpe; fcov; inhibition; mefloquine; reduction; virus cache: cord-259744-r9j5yzfc.txt plain text: cord-259744-r9j5yzfc.txt item: #77 of 161 id: cord-260092-pmufsvg9 author: Nieuwland, Mante S. title: Anticipating words during spoken discourse comprehension: A large-scale, pre-registered replication study using brain potentials() date: 2020-09-30 words: 14922 flesch: 42 summary: Aside from this issue of 'cue reliability', gender-mismatching inflections might be relatively hard to detect compared to prediction-mismatching gender-marked articles ('el/la' in Spanish, 'de/het' in Dutch), and therefore be less likely to yield prediction effects. How robust are prediction effects in language comprehension? keywords: adjective; analysis; comprehension; effect; gender; inflection; mismatch; noun; onset; ot07; participants; prediction; results; study; time; vb05 cache: cord-260092-pmufsvg9.txt plain text: cord-260092-pmufsvg9.txt item: #78 of 161 id: cord-260413-elyn2fdh author: Żółkiewicz, Jakub title: Postbiotics—A Step Beyond Pre- and Probiotics date: 2020-07-23 words: 8247 flesch: 26 summary: key: cord-260413-elyn2fdh authors: Żółkiewicz, Jakub; Marzec, Aleksandra; Ruszczyński, Marek; Feleszko, Wojciech title: Postbiotics—A Step Beyond Pre- and Probiotics date: 2020-07-23 journal: Nutrients DOI: 10.3390/nu12082189 sha: doc_id: 260413 cord_uid: elyn2fdh As an imbalance in the intestinal microbiota can lead to the development of several diseases (e.g., type 1 diabetes, cancer, among others), the use of prebiotics, probiotics, and postbiotics to alter the gut microbiome has attracted recent interest. Postbiotics include any substance released by or produced through the metabolic activity of the microorganism, which exerts a beneficial effect on the host, directly or indirectly. keywords: activity; antioxidant; bacteria; butyrate; cancer; cell; children; diseases; effects; gut; lactobacillus; microbiota; postbiotics; probiotics; properties; supernatants; use cache: cord-260413-elyn2fdh.txt plain text: cord-260413-elyn2fdh.txt item: #79 of 161 id: cord-261150-cdo7y3ob author: Fthenakis, G. C. title: Interactions between parasitic infections and reproductive efficiency in sheep date: 2015-02-28 words: 8113 flesch: 28 summary: In a field study, trematode infections (F. hepatica and D. dendriticum) in lactating multiparous ewes have led to increased incidence of clinical or subclinical mastitis during the first two weeks post-partum (Mavrogianni et al., 2014) . It is interesting to note that in one of these studies (Mavrogianni et al., 2014) , the association between trematode infection and mastitis was shown in the immediately post-partum period, when relaxation of immunity (Sections 6.2 and 8.1) would be present. keywords: administration; animals; anthelmintic; effects; energy; et al; ewes; infections; lambs; mating; milk; parasitism; period; pregnancy; production; rams; reproductive; sheep cache: cord-261150-cdo7y3ob.txt plain text: cord-261150-cdo7y3ob.txt item: #80 of 161 id: cord-267284-3uz0v29k author: Schneiderová, Kristýna title: Phytochemical profile of Paulownia tomentosa (Thunb). Steud. date: 2014-08-29 words: 8607 flesch: 27 summary: In some cases, no specific biological activity has been observed (Kim et al. 2010a (Kim et al. , 2010b Tang et al. 1994) . It has neuroprotective effects against glutamate-induced neurotoxicity (Kim et al. 2010a (Kim et al. , 2010b and cytotoxic activity against several cancer cell lines: A549 lung carcinoma; SK-OV-3 adenocarcinoma; SK-Mel-2 malignant melanoma; XF498 central nervous system tumors; HCT15 colon adenocarcinoma, against which its effect is comparable to that of reference substance adriamycin (Moon and Zee 2001) ; human breast cancers MDA-MB-231, MCF7, HS578T, and T47D; and the HeLa, SiHa and C33A cervical cancer cell lines (Jung et al. 2012) . keywords: acid; activities; activity; anti; antioxidant; cancer; cells; compounds; cytotoxic; effects; et al; flavonoids; flowers; glycosides; human; inhibition; inhibitory; leaves; paulownia; plant; rats; structure; tomentosa cache: cord-267284-3uz0v29k.txt plain text: cord-267284-3uz0v29k.txt item: #81 of 161 id: cord-267345-pmtecdko author: Hao, Da Cheng title: Phytochemical and biological research of Polygoneae medicinal resources date: 2015-07-03 words: 7017 flesch: 30 summary: Multiple instances of allopolyploid speciation were also shown in Persicaria using a low-copy nuclear gene region (LEAFY second intron) (Kim et al., 2008b) , which belong to Polygonum in Flora of China. 25,600,002 short reads (2.3 Gb) of P. cuspidatum root transcriptome were obtained via Illumina HiSeq 2000 sequencing (Hao et al., 2012) . keywords: activity; cells; cuspidatum; effects; emodin; et al; expression; glucoside; human; inhibits; medicinal; minus; multiflorum; pathway; polygonaceae; polygonum; resveratrol; root; species cache: cord-267345-pmtecdko.txt plain text: cord-267345-pmtecdko.txt item: #82 of 161 id: cord-268088-y4vg7frb author: Montané, Xavier title: Current Perspectives of the Applications of Polyphenols and Flavonoids in Cancer Therapy date: 2020-07-23 words: 11135 flesch: 39 summary: Several research groups have proved the cytotoxicity of kaempferol against breast cancer cells both in vitro and in vivo: -By inhibiting the growth of cancer cells, Flavonols are a class of flavonoids based on the backbone 3-hydroxyflavone. Several research groups have proved the cytotoxicity of kaempferol against breast cancer cells both in vitro and in vivo: -By inhibiting the growth of cancer cells, -By stopping the progression and proliferation of cancer cells, and -By inducing cancer cells apoptosis. keywords: acid; activity; anticancer; apigenin; apoptosis; breast; breast cancer; cancer; cancer cells; compounds; drug; effects; flavonoids; honokiol; plants; polyphenols; properties; resveratrol; therapy cache: cord-268088-y4vg7frb.txt plain text: cord-268088-y4vg7frb.txt item: #83 of 161 id: cord-269206-160ddfsc author: Ceylan, Rahmiye Figen title: Historical evidence for economic effects of COVID-19 date: 2020-06-04 words: 4555 flesch: 49 summary: key: cord-269206-160ddfsc authors: Ceylan, Rahmiye Figen; Ozkan, Burhan; Mulazimogullari, Esra title: Historical evidence for economic effects of COVID-19 date: 2020-06-04 journal: Thus, discussing economic effects of previous global and regional epidemics is considered beneficial. keywords: consumption; covid-19; demand; effects; flu; impact; income; labour; loss; services cache: cord-269206-160ddfsc.txt plain text: cord-269206-160ddfsc.txt item: #84 of 161 id: cord-269943-g77qe5ml author: Di Sotto, Antonella title: Plant-Derived Nutraceuticals and Immune System Modulation: An Evidence-Based Overview date: 2020-08-22 words: 13975 flesch: 28 summary: Accordingly, oleic acid is classified as a ω-9 (or n-9) fatty acid, while linoleic acid and α-linolenic acid are ω-6 (or n-6) and ω-3 (or n-3) fatty acids, as they contain the double bond nine, six and three carbons from the methyl end The role of fatty acid structure, metabolism, and possible second messenger systems Minerval induces apoptosis in Jurkat and other cancer cells Comparative toxicity of oleic acid and linoleic acid on Jurkat cells Comparative toxicity of oleic acid and linoleic acid on Raji cells Oleate protects macrophages from palmitate-induced apoptosis through the downregulation of CD36 expression Oleate but not stearate induces the regulatory phenotype of myeloid suppressor cells Skin-Specific Unsaturated Fatty Acids Boost the Staphylococcus aureus Innate Immune Response Preventive and prophylactic mechanisms of action of pomegranate bioactive constituents Modulation of peroxisome proliferator-activated receptor gamma(PPAR γ) by conjugated fatty acid in obesity and inflammatory bowel disease Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: A review of the evidence Polyunsaturated fatty acids and inflammation Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging Dietary Bioactive Fatty Acids as Modulators of Immune Function: Implications on Human Health Impact of Omega-3 Fatty Acids on the Gut Microbiota Linseed Essential Oil-Source of Lipids as Active Ingredients for Pharmaceuticals and Nutraceuticals The chemical composition, botanical characteristic and biological activities of Borago officinalis: A review. keywords: acid; activation; activity; anti; astragalus; cancer; cells; chain; effects; fatty; function; glucan; immune; immunity; immunomodulatory; inflammation; labdane; levels; macrophages; oil; plant; polysaccharides; production; properties; pufa; response; studies; system; ω-3 cache: cord-269943-g77qe5ml.txt plain text: cord-269943-g77qe5ml.txt item: #85 of 161 id: cord-270337-92a5uwjf author: Hughes, Dyfrig A. title: Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam date: 2020-06-18 words: 6514 flesch: 41 summary: The observation in 1976 of a patient who took 5 g of chloroquine together with 500 mg of diazepam and survived without symptoms of chloroquine toxicity (Djelardje, 1976) , drew attention to the possible role of diazepam in chloroquine poisoning. For example, the PR interval increased from 52 ± 3 to 68 ± 4 ms during the first 12 min in ventilated rats receiving 1 mgÁkg −1 Ámin −1 chloroquine, and from 50 ± 2 to 68 ± 4 ms during the first 6 min at twice the infusion rate, with both groups receiving a total of 12 mgÁkg −1 of chloroquine over these periods. keywords: administration; atria; cardiac; chloroquine; diazepam; effects; mgákg; min; rats; toxicity; ventricular cache: cord-270337-92a5uwjf.txt plain text: cord-270337-92a5uwjf.txt item: #86 of 161 id: cord-270673-apr9oyqa author: Rosselló, Jaume title: The effects of natural disasters on international tourism: A global analysis date: 2020-02-01 words: 8580 flesch: 41 summary: Time to &loop the loop Tourism disaster planning and management: From response and recovery to reduction and readiness Understanding the effects of a tourism crisis: The impact of the BP oil spill on regional lodging demand Infectious disease risk and international tourism demand Measuring tourism risk impacts on destination image Natural disaster tourism as type of dark tourism Natural hazard and disaster tourism The effect of safety and security issues on international Tourism Modelling tourism flows through gravity models: A quantile regression approach Social amplification and attenuation of climate change risk in a vulnerable tourism destination Investigating the role of prior knowledge in tourist decision making: A structural equation model of risk perceptions and information search Identifying risks facing the South African tourism industry Disaster tourism and disaster landscape attractions after Hurricane Katrina Tourism in crisis: Managing the effects of terrorism A cognitive-affective scale for hurricane risk perception The risk perception paradox-implications for governance and communication of natural hazards Cape town's water crisis hitting tourism: Officials Tourism risk and uncertainty: Theoretical reflections Caribbean resilience and recovery: Minimising the impact of the 2017 hurricane season on the caribbean's tourism sector Do political instability, terrorism and corruption have deterring effects on tourism development even in the presence of UNESCO heritage? Through this strategy, it is possible to explore in detail if effects arise that counteract the initially expected negative relationship between disaster impacts and tourism flows. keywords: arrivals; country; damage; deaths; destination; disaster; effects; events; impact; number; people; relationship; research; risk; tourism; types cache: cord-270673-apr9oyqa.txt plain text: cord-270673-apr9oyqa.txt item: #87 of 161 id: cord-271122-3fsl5589 author: Wathes, D. Claire title: Importance of Viral Disease in Dairy Cow Fertility date: 2019-07-24 words: 7116 flesch: 39 summary: optimizing performance of the Offspring: nourishing and managing the dam and postnatal calf for optimal lactation, reproduction, and immunity Control of bovine viral diarrhea virus in ruminants Herd-level prevalence of selected endemic infectious diseases of dairy cows in Great Britain BVDV genotypes and biotypes: practical implications for diagnosis and control Pestiviruses: how to outmaneuver your hosts Viral quasispecies Establishment of persistent infection with non-cytopathic bovine viral diarrhoea virus in cattle is associated with a failure to induce type I interferon Differential activation of interferon regulatory factors-3 and -7 by non-cytopathogenic and cytopathogenic bovine viral diarrhoea virus Association of bovine embryos produced by in vitro fertilization with a noncytopathic strain of bovine viral diarrhea virus type II Epidemiology of prolonged testicular infections with bovine viral diarrhea virus Infectivity of pestivirus following persistence of acute infection Bovine viral diarrhoea: pathogenesis and diagnosis Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus TRIM56 is a virus-and interferoninducible E3 ubiquitin ligase that restricts pestivirus infection Pestiviral E rns blocks TLR-3-dependent IFN synthesis by LL37 complexed RNA A field investigation of the effects of bovine viral diarrhea virus infection around the time of insemination on the reproductive performance of cattle The effects of bovine viral diarrhoea virus on cattle reproduction in relation to disease control The effect of infection with bovine viral diarrhea virus on the fertility of Swiss dairy cattle Reproductive and economic impact following controlled introduction of cattle persistently infected with bovine viral diarrhea virus into a naive group of heifers Efficacy of bovine viral diarrhea virus vaccination to prevent reproductive disease: a meta-analysis Changes in ovarian follicles following acute infection with bovine viral diarrhea virus Bovine viral diarrhoea virus: its effects on ovarian function in the cow The effect of bovine pestivirus infection on the superovulatory response of Friesian heifers Reproductive consequences of infection with bovine viral diarrhea virus Detection of bovine viral diarrhea virus in the ovaries of cattle acutely infected with bovine viral diarrhea virus Modulation of sex hormone secretion in cows by acute infection with bovine viral diarrhoea virus What is stress, and how does it affect reproduction? Effect of bovine viral diarrhea virus on the endometrial response to lipopolysaccharide Acute bovine viral diarrhea virus infection inhibits expression of interferon s-stimulated genes in bovine endometrium BVDV alters uterine prostaglandin production during pregnancy recognition in cows Steroidal regulation of uterine resistance to bacterial infection in livestock Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F 2 a to prostaglandin E 2 in bovine endometrium Effect of interferon-s on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of prostaglandin E 2 Risk factors for post partum ovarian dysfunction in high producing dairy cows in Belgium: a field study Sexual dimorphism in interferon-tau production by in vivo-derived bovine embryos Interferon-s, a type 1 interferon involved in maternal recognition of pregnancy The oxytocin receptor, luteolysis and the maintenance of pregnancy Maternal-embryo interaction leading up to the initiation of implantation of pregnancy in cattle Trophoblast interferons Pregnancy recognition signaling mechanisms in ruminants and pigs Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant? keywords: bovine; bvdv; calving; cattle; cows; dairy; diarrhea; disease; effects; embryos; evidence; fertility; infection; rates; virus cache: cord-271122-3fsl5589.txt plain text: cord-271122-3fsl5589.txt item: #88 of 161 id: cord-271785-vmnc8yg6 author: Minetti, Giampaolo title: Mevalonate pathway, selenoproteins, redox balance, immune system, Covid-19: Reasoning about connections date: 2020-07-21 words: 2555 flesch: 30 summary: 8, 9 Prolonged infection with hepatitis B virus has been show to correlate with low blood cholesterol levels and cancer, 10 and hypocholesterolemic men have significantly fewer circulating lymphocytes, total T cells and CD8 + cells compared with hypercholesterolemic subjects. A couple of studies have indeed been published that exclude a statistically significant correlation between Covid-19 outcome and statin routine treatment of patients, but no data on compliance, or cholesterol levels were provided. keywords: cholesterol; effects; infection; levels; pathway; statins; subjects cache: cord-271785-vmnc8yg6.txt plain text: cord-271785-vmnc8yg6.txt item: #89 of 161 id: cord-272309-v72796pu author: Tootee, Ali title: Ramadan fasting during Covid-19 pandemic date: 2020-04-30 words: 2077 flesch: 26 summary: Payesh (Health Monitor) Islamic principles and decision making in bioethics Caloric intake and aging Fasting: molecular mechanisms and clinical applications Effects of intermittent fasting on health, aging, and disease Intermittent metabolic switching, neuroplasticity and brain health Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia Shortterm caloric restriction exerts neuroprotective effects following mild traumatic brain injury by promoting autophagy and inhibiting astrocyte activation Ramadan fasting, mental health and sleep-wake pattern Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women Caloric restriction improves health and survival of rhesus monkeys Caloric restriction and cancer: molecular mechanisms and clinical implications Fasting and cancer: molecular mechanisms and clinical application Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities Fasting followed by vegetarian diet in patients with rheumatoid arthritis: a systematic review Diet-induced weight loss in obese children with asthma: a randomized controlled trial A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms COVID-19-looking beyond tomorrow for health care and society Ramadan during COVID-19: What clerics and health experts say, in Gulf News Effects of Ramadan fasting on serum immunoglobulin G and M, and salivary immunoglobulin a concentrations The effect of fasting on the immune system of athletes during holly Ramadan The effect of Ramadan fasting on blood biochemical factors related to immune system in summer Effect of Ramadan fasting on the ability of serum, PBMC and macrophages from healthy subjects to kill M. tuberculosis Ramadan fasting and infectious diseases: a systematic review Ayatollah Sistani's Fatwa on Fasting during Ramadan in the Shadow of Coronavirus Ramadan Fasting amid Corona Virus Pandemic in Academy of Medical Sciences Islamic fasting and health Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations [15] These evidence and similar findings indicate that the effects of Ramadan Fasting are not merely confined those related to refraining from eating and drinking, and they include a diverse range of physical, psychological, and spiritual health. keywords: effects; evidence; fasting; health; ramadan; risk cache: cord-272309-v72796pu.txt plain text: cord-272309-v72796pu.txt item: #90 of 161 id: cord-272465-i2l4cq8h author: Law, Betty Yuen Kwan title: New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy date: 2016-03-17 words: 16375 flesch: 24 summary: Therefore, cancer intervention with the use of autophagy inducers can trigger both autophagic cell death and physiological changes, such as cell cycle arrest, on cancer cells. For example, cepharanthine abolished the drug resistance property of cancer cells by modulating the activities of multidrug resistance factor ABCC10 (MRP7) and ATPase keywords: activation; activity; akt; ampk; anti; apoptosis; autophagy; blood; cancer; cancer cells; carcinoma; cell death; cells; chinese; clinical; death; disease; effects; herb; human; induction; inhibition; kinase; mtor; novel; pathway; potential; protein; radix; regulation; rhizoma; role; signaling; stress; therapeutic; treatment; tumor cache: cord-272465-i2l4cq8h.txt plain text: cord-272465-i2l4cq8h.txt item: #91 of 161 id: cord-276006-mjjnkqv6 author: Jarach, Natanel title: Polymers in the Medical Antiviral Front-Line date: 2020-07-31 words: 12601 flesch: 37 summary: Some other molecules with antiviral effects are 5-(N-ethyl-N-isopropyl)amiloride (EIPA), verapamil, and diltiazem. Silver (Ag) particles have an antiviral effect even in their metal form; Yamamoto et al. showed that the addition of Ag particles to a cotton textile granted it antiviral effect against Influenza A and Feline Calicivirus [76] . keywords: acid; activity; addition; ammonium; drugs; effect; et al; figure; influenza; ions; metal; nanoparticles; particles; polymers; properties; rna; sulphate; temperature; virus; viruses cache: cord-276006-mjjnkqv6.txt plain text: cord-276006-mjjnkqv6.txt item: #92 of 161 id: cord-279166-kt35mg7o author: Howell, Amy B. title: The Pomegranate: Effects on Bacteria and Viruses That Influence Human Health date: 2013-05-20 words: 6634 flesch: 40 summary: Pomegranate extract was evaluated in several studies for the ability to decontaminate meat surfaces and maintain food quality. Pomegranate extract had a beneficial effect on rumen bacterial populations in lactating cows keywords: activity; antibacterial; effects; extract; granatum; human; juice; peel; polyphenols; pomegranate; punica; study; virus; viruses cache: cord-279166-kt35mg7o.txt plain text: cord-279166-kt35mg7o.txt item: #93 of 161 id: cord-279586-likfvwwj author: Jin, Jian title: Effects of Sonication on the In vitro Digestibility and Structural Properties of Buckwheat Protein Isolates date: 2020-09-17 words: 4837 flesch: 40 summary: Sonication mostly decreased the PDI, suggesting that the dispersion of proteins occurred in a narrower molecular weight distribution, possibly ascribed to the formation of aggregates or to swelling of protein particles. Taken together, sonication has proven to be a promising approach for improving the digestibility of buckwheat proteins, which can be explored as a source of plant-based alternative protein for food applications. keywords: amplitude; bpis; buckwheat; content; digestibility; min; protein; sonication; structure; surface; ultrasound cache: cord-279586-likfvwwj.txt plain text: cord-279586-likfvwwj.txt item: #94 of 161 id: cord-280605-2i4gk7et author: Bachmann, María Consuelo title: The Challenge by Multiple Environmental and Biological Factors Induce Inflammation in Aging: Their Role in the Promotion of Chronic Disease date: 2020-10-14 words: 11154 flesch: 18 summary: The impact on Tregulatory cell related immune responses in rural women exposed to polycyclic aromatic hydrocarbons (PAHs) in household air pollution in Gansu, China: A pilot investigation PM 2.5 induced pulmonary fibrosis in vivo and in vitro Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF-b1-Dependent and -Independent Mechanisms Effects of sub-chronic exposure to atmospheric PM2.5 on fibrosis, inflammation, endoplasmic reticulum stress and apoptosis in the livers of rats Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived Effects of airborne pollutants on mitochondrial DNA Methylation Prenatal particulate air pollution and DNA methylation in newborns: An epigenomewide meta-analysis Dose-and time-effect responses of DNA methylation and histone H3K9 acetylation changes induced by traffic-related air pollution Air pollution and DNA methylation: Effects of exposure in humans Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review Air pollution, particulate matter composition and methylation-based biologic age Air Pollution Stress and the Aging Phenotype: The Telomere Connection The effect of exposure time and concentration of airborne PM2.5 on lung injury in mice: A transcriptome analysis Facing up to the global challenges of ageing Coming of age: molecular drivers of aging and therapeutic opportunities Find the latest version: Review series introduction Coming of age: molecular drivers of aging and therapeutic opportunities Disability incidence and functional decline among older adults with major chronic diseases Quality of life assessment instruments for adults: a systematic review of population-based studies Comparative financing analysis and political economy of noncommunicable diseases The integration of inflammaging in age-related diseases Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimer's disease pathophysiology Source of Chronic Inflammation in Aging Microglial cell dysregulation in brain aging and neurodegeneration Aging and the immune system: An overview Cellular senescence and Alzheimer disease: the egg and the chicken scenario The epigenetics of inflammaging: The contribution of age-related heterochromatin loss and locus-specific remodelling and the modulation by environmental stimuli These sex-related differences can determine the ability of immune cells to generate an effective inflammatory response, which translates into epidemiological differences on the prevalence of various pathologies, including allergies (22), asthma (23, 24), autoimmune diseases (25), anaphylaxis (26), neonatal sepsis (27), and cancer (28), among several pathologies. keywords: activation; age; aging; cells; changes; cytokines; damage; diet; diseases; effects; exercise; exposure; expression; factors; immune; inflammation; levels; mechanisms; methylation; oxidative; production; response; sex; stress; system cache: cord-280605-2i4gk7et.txt plain text: cord-280605-2i4gk7et.txt item: #95 of 161 id: cord-282101-2usqpy2j author: Hassan, Atef A. title: Nanomaterials and nanocomposite applications in veterinary medicine date: 2020-05-01 words: 17183 flesch: 17 summary: Therefore, the measurement of effective nontoxic doses of metal nanoparticles in laboratory animal models must be undertaken to study the suitability of their field application (Abd El-Fatah et al., 2017; Asharani et al., 2008; Hassan et al., 2017; Shaw et al., 2008) . The antifungal potential of chitosan and CS NPs against Fusarium graminearum colonies was evaluated, may be used as a novel nano-biopesticides (Kheiri et al., 2016) and a growth inhibitor for Rhizopus sp. keywords: ability; activity; addition; agents; animal; antibacterial; applications; cancer; carbon; cells; chitosan; delivery; detection; diagnosis; disease; drug; effects; et al; fluorescent; food; growth; hassan et; health; human; imaging; metal; mice; nanomaterials; nanoparticles; nanotechnology; nps; oxide; potential; production; silica; silver; studies; synthesis; therapy; toxicity; treatment; zinc cache: cord-282101-2usqpy2j.txt plain text: cord-282101-2usqpy2j.txt item: #96 of 161 id: cord-286610-woqb1t06 author: Choukér, Alexander title: COVID-19—The largest isolation study in history: the value of shared learnings from spaceflight analogs date: 2020-10-22 words: 5598 flesch: 21 summary: The prevalence of social isolation and loneliness in response to the COVID-19 pandemic is currently unclear, with estimates varying between 16 and 25% 3 . Here, we summarize the opportunities of spaceflight analogs to accelerate (1) the understanding of the neurobehavioral and immunological consequences of social isolation during the COVID-19 pandemic, and (2) the development of innovative and efficient treatment strategies to mitigate adverse behavioral conditions. keywords: brain; confinement; covid-19; data; effects; health; isolation; life; pandemic; research; space; spaceflight; stress; system cache: cord-286610-woqb1t06.txt plain text: cord-286610-woqb1t06.txt item: #97 of 161 id: cord-287243-fm3587ww author: Scanes, Colin G. title: Reproductive management of poultry date: 2020-01-24 words: 6830 flesch: 43 summary: Increased egg production by active immunization against vasoactive intestinal peptide in the turkey (Meleagris gallopavo) In the USA, there were 114 million broiler breeder pullets placed for broiler egg production (and hence broiler chick) in 2017. keywords: broiler; chicken; concentrations; egg; expression; feed; hens; hormone; light; molting; plasma; poultry; production; white; yolk cache: cord-287243-fm3587ww.txt plain text: cord-287243-fm3587ww.txt item: #98 of 161 id: cord-289599-7vsynfgn author: Kostoff, Ronald N. title: COVID-19 vaccine safety date: 2020-09-18 words: 2715 flesch: 35 summary: Questions have been raised as to whether an accelerated vaccine development can be accomplished safely, preventing potential adverse vaccine effects not only in the short-term, but also in the mid-and long-term (https://smartech.gatech.edu/handle/1853/63710). Regulatory Affairs Professionals Society Towards effective cOVId-19 vaccines: Updates, perspectives and challenges (Review) keywords: covid-19; effects; mid; population; potential; term; vaccine cache: cord-289599-7vsynfgn.txt plain text: cord-289599-7vsynfgn.txt item: #99 of 161 id: cord-291559-h6czy5bh author: Koirala, Prashamsa title: Recent advances in pharmacological research on Ecklonia species: a review date: 2017-08-24 words: 12291 flesch: 22 summary: Dieckol and PFF-A obtained from boiling water-and organic solvent extracts of EC and ES showed almost 9-and 7-fold stronger antioxidant activity than the standard butylhydroxytoluene, and 6-and 4-fold greater activity than l-ascorbic acid in molar concentration, Anti-inflammatory activity Ecklonia cava Dieckol Decreased blood glucose level Kang et al. Undaria pinnatifida and Ecklonia stolonifera Antibacterial activities of marine epibiotic bacteria isolated from brown algae of Japan Antioxidant and anti-inflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture A new phlorotannin from the brown alga Ecklonia stolonifera Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo Dieckol isolated from brown seaweed Ecklonia cava attenuates type II diabetes in db/db mouse model Protective effect of dieckol isolated from Ecklonia cava against ethanol caused damage in vitro and in zebrafish model Phlorotannin-rich Ecklonia cava reduces the production of betaamyloid by modulating alpha-and gamma-secretase expression and activity Dieckol, a component of Ecklonia cava, suppresses the production of MDC/CCL22 via down-regulating STAT1 pathway in interferon-c stimulated HaCaT human keratinocytes Acetylcholinesterase inhibitory activity of phlorotannins isolated from the brown alga, Ecklonia maxima (Osbeck) Papenfuss Anti-HIV-1 activity of phlorotannin derivative 8,4 000 -dieckol from Korean brown alga Ecklonia cava Phlorotannins suppress adipogenesis in pre-adipocytes while enhancing osteoblastogenesis in pre-osteoblasts Role of ERK/MAPK signaling pathway in antiinflammatory effects of Ecklonia cava in activated human mast cell line-1 cells Enzyme-treated Ecklonia cava extract inhibits adipogenesis through the downregulation of C/EBPa in 3T3-L1 adipocytes Hepatoprotective constituents of the edible brown alga Ecklonia stolonifera on tacrine-induced cytotoxicity in HepG2 cells Isolation and identification of phlorotannins from Ecklonia stolonifera with antioxidant and anti-inflammatory properties keywords: activity; algae; anti; brown; cancer; cava; cells; dieckol; ecklonia; ecklonia cava; effects; et al; expression; extract; glucose; human; inhibited; inhibitory; marine; mice; oxidative; pff; phlorotannins; potential; production; protein; ros cache: cord-291559-h6czy5bh.txt plain text: cord-291559-h6czy5bh.txt item: #100 of 161 id: cord-293139-uj1m3t79 author: Hua, Jinxi title: Competing PM2.5 and NO2 holiday effects in the Beijing area vary locally due to differences in residential coal burning and traffic patterns date: 2020-08-11 words: 4912 flesch: 44 summary: The relatively high uncertainty of holiday effects is due to the fact that there are fewer data points for the holiday periods than for the non-holidays. key: cord-293139-uj1m3t79 authors: Hua, Jinxi; Zhang, Yuanxun; de Foy, Benjamin; Mei, Xiaodong; Shang, Jing; Feng, Chuan title: Competing PM2.5 and NO2 holiday effects in the Beijing area vary locally due to differences in residential coal burning and traffic patterns date: 2020-08-11 journal: Sci Total Environ DOI: 10.1016/j.scitotenv.2020.141575 sha: doc_id: 293139 cord_uid: uj1m3t79 Abstract The holiday effect is a useful tool to estimate the impact on air pollution due to changes in human activities. keywords: air; beijing; concentrations; effect; et al; holiday; pollution; sites cache: cord-293139-uj1m3t79.txt plain text: cord-293139-uj1m3t79.txt item: #101 of 161 id: cord-295335-oa4twg2z author: Pastorino, Giulia title: Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review date: 2018-08-17 words: 8276 flesch: 26 summary: Antidepressive activity G. glabra aqueous extract 75-300 mg/kg The use of G. glabra extract as antiulcerative is widely known. keywords: 18β; acid; activity; antioxidant; apoptosis; cells; compounds; effects; et al; extract; g. glabra; glabra; glabridin; glycyrrhetinic; glycyrrhiza glabra; glycyrrhizin; inhibition; licochalcone; licorice; liquorice; mice; root; treatment cache: cord-295335-oa4twg2z.txt plain text: cord-295335-oa4twg2z.txt item: #102 of 161 id: cord-295807-68sukdb1 author: Quade, Bianca N. title: The therapeutic importance of acid-base balance date: 2020-10-09 words: 20817 flesch: 36 summary: The direct secretion of these drugs into the nephron lumen is necessary because many such drugs are substantially bound to albumin in circulation and are not effectively filtered into the nephron lumen at the glomerulus. Numerous acid-base handling proteins are upregulated in rapidly proliferating tumor calls to help them dispose of metabolic acids and create an acidic microenvironment that disadvantages non-tumor cells in their vicinity. keywords: abts; acid; acidosis; action; balance; base; bicarbonate; blood; cancer; cells; cftr; chronic; co2; disease; drug; effect; example; fluid; hco3; influence; kidney; load; mac; metabolic; mice; nahco3; patients; potential; renal; response; role; salivary; secretion; section; sodium; study; system; therapy; treatment; tumor cache: cord-295807-68sukdb1.txt plain text: cord-295807-68sukdb1.txt item: #103 of 161 id: cord-297597-tqc1usry author: Godden, Sandra title: Colostrum Management for Dairy Calves date: 2008-02-23 words: 7700 flesch: 44 summary: A guide to colostrum and colostrum management for dairy calves Evaluation of the hydrometer for testing immunoglobulin G 1 concentrations in Holstein colostrum Evaluation of a cow-side immunoassay kit for assessing IgG concentration in colostrum Comparison of three methods of feeding colostrum to dairy calves Effects of quality, quantity, and timing of colostrum feeding and addition of a dried colostrum supplement on immunoglobulin G1 absorption in Holstein bull calves Electron microsopic studies of the jejunal epithelium from neonatal pigs fed different diets The ultrastructure of neonatal calf intestine and absorption of heterologous proteins Effect of colostral immunoglobulin G1 and immunoglobulin M concentrations on immunoglobulin absorption in calves Intestinal transmission of macromolecules in newborn dairy calves of different ages at first feeding Colostral immunoglobulin transfer in calves I. Period of absorption Effect of suckling followed by bottle feeding colostrum on immunoglobulin absorption and calf survival The period between birth and first suckling in dairy calves The failure of the oesophageal groove reflex, when fluids are given with an oesophageal feeder to newborn and young calves Two methods for administering colostrum to newborn calves Colostrum management in calves: effects of drenching vs. bottle feeding Studies on dairy calves allowed to suckle their dams at fixed times postpartum Decreased colostral immunoglobulin absorption in calves with postnatal respiratory acidosis Hypoxia in neonatal calves: Effect on intestinal transport of immunoglobulins Effect of high arterial carbon dioxide tension on efficiency of immunoglobulin G absorption in calves Effects of maternal nutritional restriction and cold stress on young calves: absorption of colostral immunoglobulins Effect of orally administered duodenal fluid on serum proteins in neonatal calves Influence of administered indigenous microorganisms on uptake of [iodine-125] gamma-globulin in vivo by intestinal segments of neonatal calves Bacteria in colostrum: impact on calf health Most, but not all, studies report a tendency for older cows to produce higher quality colostrum, presumably because of older animals have had a greater period of exposure to farm-specific pathogens keywords: absorption; calf; calves; colostral; colostrum; cows; dairy; fed; feeding; hours; igg; management; quality; serum cache: cord-297597-tqc1usry.txt plain text: cord-297597-tqc1usry.txt item: #104 of 161 id: cord-298265-elbnzgx6 author: Mutua, Victoria title: A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics date: 2020-08-01 words: 10425 flesch: 29 summary: formation Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens How neutrophils kill microbes Neutrophil extracellular traps (NET) induced by different stimuli: a comparative proteomic analysis Neutrophil extracellular traps profiles in patients with incident systemic lupus erythematosus and lupus nephritis Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps NLRP3 activation induced by neutrophil extracellular traps sustains inflammatory response in the diabetic wound The influence of hyperglycemia on neutrophil extracellular trap formation and endothelial Pathogenesis and therapy of psoriasis Neutrophil extracellular traps and their role in the development of chronic inflammation and autoimmunity Regulating neutrophil apoptosis: new players enter the game Mechanisms of B cell autoimmunity in SLE Systemic lupus erythematosus Immunological pathogenesis and treatment of systemic lupus erythematosus Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus Review article neutrophil function in an inflammatory milieu of rheumatoid arthritis Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis Proinflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis Rev Médica del Diabetes primes neutrophils to undergo NETosis, which impairs wound healing The adipose tissue as a source of vasoactive factors Adipocytes properties and crosstalk with immune system in obesity-related inflammation Neutrophil extracellular traps and cardiovascular diseases: an update Increased plasmatic NETs by-products in patients in severe obesity In vivo and in vitro studies on the roles of neutrophil extracellular traps during secondary pneumococcal pneumonia after primary pulmonary influenza infection Effect of high-fat diet on the formation of pulmonary neutrophil extracellular traps during influenza pneumonia in BALB/c mice Role of thromboxane-dependent platelet activation in venous thrombosis: aspirin effects in mouse model Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury Aspirin-triggered 15-epi-lipoxin a4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice Activation of platelet function through G protein-coupled receptors Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury Aspirin, but NotTirofiban displays protective effects in endotoxin induced lung injury Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation Regulation of neutrophil extracellular trap formation by anti-inflammatory drugs Mechanisms of action of cyclosporine Cyclosporine: a review Cyclosporine in veterinary dermatology Molecular mechanisms of action of some immunosuppressive drugs Efficient neutrophil extracellular trap induction requires mobilization of both intracellular and extracellular calcium pools and is modulated by cyclosporine A. PLoS One:9 Posttransplant infections in the tropical countries Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer AA et alPeptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice NETosis delays diabetic wound healing in mice and humans keywords: activation; cells; conditions; damage; disease; effects; extracellular; formation; histones; human; inflammation; inhibition; injury; mice; netosis; nets; neutrophil; patients; production; protein; studies; traps; treatment cache: cord-298265-elbnzgx6.txt plain text: cord-298265-elbnzgx6.txt item: #105 of 161 id: cord-299007-5m6lk409 author: Paterson, R. Russell M. title: Cordyceps – A traditional Chinese medicine and another fungal therapeutic biofactory? date: 2008-05-31 words: 19555 flesch: 36 summary: The effects of aqueous extracts of some crude drugs in shortterm screening test Militarinone A, a neurotrophic pyridone alkaloid from Paecilomyces militaris (+)-N-Deoxymilitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus Down-regulation of apoptotic and inflammatory genes by Cordyceps sinensis extract in rat kidney following ischemia/reperfusion Treatment of hyperlipidemia with cultivated Cordyceps -a double-blind, randomized placebo control trial Trade of Cordyceps sinensis from high altitudes of the Indian Himalaya: conservation and biotechnological priorities Effect of Cordyceps militaris on the damage of rats induced by n-hexane Profiles of nucleosides and nitrogen bases in Chinese medicinal fungus Cordyceps sinensis and related species Pharmacological activities of Paecilomyces japonica, a new type Cordyceps sp Anti-tumour and immuno-stimulating activities of the fruiting bodies of Paecilomyces japonica, a new type of Cordyceps spp Antioxidant and immunostimulating activities of the fruiting bodies of Paecilomyces japonica, a new type of Cordyceps sp Pharmacological basis of 'Yin-nourishing' and 'Yang-invigorating' actions of Cordyceps, a Chinese tonifying herb Chemotaxonomy of Pochonia and other conidial fungi with Verticillium like anamorphs Clinical study on application of bailing capsule after renal transplantation Cordyceps sinensis and cultured mycelia Phylogenetic classification of Cordyceps and the clavicipitaceous fungi Effects of Cordyceps sinensis, rhubarb and serum renotropin on tubular epithelial cell growth DMSO modifies structural and functional properties of RPMI-8402 cells by promoting programmed cell death Rapid and specific detection of hydroxyl radical using an ultraweak chemiluminescence analyzer and a low-level chemiluminescence emitter: application to hydroxyl radicalscavenging ability of aqueous extracts of food constituents Free radical scavenging and apoptotic effects of Cordyceps sinensis fractionated by supercritical carbon dioxide Effects of a watersoluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells Pharmacological functions of Chinese medicinal fungus Cordyceps sinensis and related species An experimental study on anti-aging action of Cordyceps extract Entomogenous fungi that produce 2,6-pyridine dicarboxylic acid (dipicolinic acid) Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae Anti-inflammatory and related pharmacological activities of cultured mycelia and fruiting bodies of Cordyceps militaris Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports Structural analysis of a neutral (1 ? 3),(1 ? Carbohydr Macrophage biospecific extraction and high performance liquid chromatography for hypothesis of immunological active components in Cordyceps sinensis Simultaneous determination of free ergosterol and ergosteryl esters in Cordyceps sinensis by HPLC Anti-diabetic effects of CCCA, CMESS, and Cordycepin from Cordyceps militaris and the immune responses in streptozotocin-induced diabetic mice Prosecutable function of Cordyceps sinensis extracts for hepatic mitochondrial oxidative injuries in diabetic mice Induction of HL-60 apoptosis by ethyl acetate extract of Cordyceps sinensis fungal mycelium Activation of murine peritoneal macrophages by natural Cordyceps sinensis and its cultured mycelia Lewis lung cancer of mice treated with Cordyceps sinensis and its artificial cultured mycelia Effects of the exopolysaccharide fraction (EPSF) from a cultivated Cordyceps sinensis on immunocytes of H22 tumor bearing mice Immunomodulatory and antitumour effects of an exopolysaccharide fraction from cultivated Cordyceps sinensis (Chinese caterpillar fungus) on tumourbearing mice Dynamical influence of Cordyceps sinensis on the activity of hepatic insulinase of experimental liver cirrhosis Influence of Cordyceps sinensis on pancreatic islet beta cells in rats with experimental liver fibrogenesis Epicoccins A-D, pipolythiodioxopiperazines from a Cordyceps-colonizing isolate of Epicoccum nigrum Clinical and experimental studies on elimination of oxygen free radical of jinshuibao capsule in treating senile deficiency syndrome and its deoxyribonucleic acid damage repairing effects Cordyceps sinensis -I as an immunosuppressant in heterotopic heart allograft model in rats CordyMax Cs-4 improves glucose metabolism and increases insulin sensitivity in normal rats Inhibitory effect of Cordyceps sinensis and Cordyceps militaris on human glomerular mesangial cell proliferation induced by native LDL Investigation on distribution and habitat of Blaps rynchopetera fairmaire (Coleoptera: Tenebrionidae) in Yunnan Cordyceps sinensis in protection of the kidney from cyclosporine keywords: activities; activity; anti; apoptosis; authors; bodies; body; cells; compounds; cordyceps; cordyceps sinensis; cultured; effects; et al; extracts; fungal; fungi; fungus; growth; human; insect; medicine; mice; militaris; mycelia; polysaccharide; production; proliferation; rats; sinensis; species; treatment; tumour cache: cord-299007-5m6lk409.txt plain text: cord-299007-5m6lk409.txt item: #106 of 161 id: cord-299363-y7o8ovf9 author: Guliyev, Hasraddin title: Determining the spatial effects of COVID-19 using the spatial panel data model date: 2020-04-07 words: 3128 flesch: 53 summary: Using spatial panel models, we analyse the relationship between confirmed cases of COVID-19, deaths thereof, and recovered cases due to treatment. Using spatial panel models, we analyse the relationship between the rate of confirmed cases (R c ) of COVID-19, the rate of deaths (R d ), the rate of recovered cases (R r ) due to treatment, with spatial and temporal effects. keywords: cases; effects; model; rate; spatial cache: cord-299363-y7o8ovf9.txt plain text: cord-299363-y7o8ovf9.txt item: #107 of 161 id: cord-299424-qy3lccjq author: MUBAGWA, Kanigula title: Chloroquine cardiac effects and toxicity.A short update. date: 2020-06-19 words: 8958 flesch: 37 summary: In addition, at high chloroquine concentrations loss of excitability and suppressed conduction (due to chloroquine effects on the upstroke of the action potential) might account for an apparent loss of contraction. The mechanisms underlying chloroquine effects include direct actions on ion channels and receptors, while others (especially a cardiomyopathy developing following long-term treatment) involve the inhibition of autophagy. keywords: action; autophagy; cardiac; channels; chloroquine; drugs; effects; heart; hydroxychloroquine; inhibition; potential; remodeling cache: cord-299424-qy3lccjq.txt plain text: cord-299424-qy3lccjq.txt item: #108 of 161 id: cord-299547-9i8kv8p8 author: Aucejo, Esteban M. title: The Impact of COVID-19 on Student Experiences and Expectations: Evidence from a Survey date: 2020-08-27 words: 5276 flesch: 47 summary: We are interested in the causal impact of COVID-19 on student outcomes: where the first term on the right-hand side is student i 's outcome in the state of the world with COVID-19, and the second term being student 6 The better performance on admission tests could be explained by the high proportion of Honors students in our sample (22% compared to 18% in the ASU population). keywords: covid-19; effects; graduation; health; income; outcomes; students cache: cord-299547-9i8kv8p8.txt plain text: cord-299547-9i8kv8p8.txt item: #109 of 161 id: cord-299613-5ju5fcf4 author: Arthi, Vellore title: Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19 date: 2020-11-03 words: 17514 flesch: 39 summary: Although urban centers were associated with higher pandemic mortality, the opposite population gradient prevailed when comparing among cities, or among rural areas: in both cases, smaller, less dense localities fared worse (Acuna-Soto et al., 2011; Chowell et al., 2008) , suggestive perhaps of capacity constraints in the healthcare workforce and medical infrastructure. Likewise, foreign-born status not only predicted higher pandemic mortality in Hartford, Connecticut, but the relationship between nativity and mortality persisted even after controlling for socioeconomic status, population density, and neighborhood ethnic composition, indicating perhaps a role for social factors, or language or cultural barriers to the adoption of relevant public health measures (Tuckel et al., 2006) . keywords: 1918; covid-19; crisis; data; disease; effects; et al; evidence; exposure; health; history; human; income; individuals; influenza; influenza pandemic; instance; labor; market; mortality; pandemic; past; population; rates; run; u.s cache: cord-299613-5ju5fcf4.txt plain text: cord-299613-5ju5fcf4.txt item: #110 of 161 id: cord-301539-9acp0m33 author: Lin, Chih-Yin title: Potential Role of Nrf2 Activators with Dual Antiviral and Anti-Inflammatory Properties in the Management of Viral Pneumonia date: 2020-06-11 words: 2418 flesch: 25 summary: 2 Interestingly, curcumin and some triterpenoids were proven to be nuclear factor erythroid 2-related factor 2 (Nrf2) activators, and the potential role of Nrf2 activators in the management of respiratory viral infection has drawn some scientists' attention. The efficacy of macrolides in respiratory viral infections and inflammatory diseases has been extensively researched, 35, 36 and their anti-inflammatory profiles are similar to the aforementioned Nrf2 activators. keywords: activators; curcumin; effects; influenza; nrf2; pneumonia; virus cache: cord-301539-9acp0m33.txt plain text: cord-301539-9acp0m33.txt item: #111 of 161 id: cord-302398-gsg6akaz author: Wu, Mengjie title: Microplastics in waters and soils: Occurrence, analytical methods and ecotoxicological effects date: 2020-10-01 words: 10327 flesch: 34 summary: Widely-recognized problems facing organisms are entanglement, suffocation and ingestion that are caused by MPs (Lo and Chan, 2018; Wu et al., 2018; Yang et al., 2015 Yang et al., , 2018 , and many studies have shown that MPs might pose threat to marine zooplanktons, fish, mussels and algae (Besseling et al., 2015; Desforges et al., 2015; Galloway et al., 2017; Lusher et al., 2015; Qin, 2012) . Yang et al., 2005; Zhou et al., 2018) . keywords: characterization; density; digestion; distribution; effects; environment; et al; freshwater; human; identification; marine; methods; microplastics; mps; organisms; samples; sampling; sediments; separation; soil; studies; surface; water cache: cord-302398-gsg6akaz.txt plain text: cord-302398-gsg6akaz.txt item: #112 of 161 id: cord-305240-r6i7d06v author: Dimitrova-Shumkovska, Jasmina title: Potential Beneficial Actions of Fucoidan in Brain and Liver Injury, Disease, and Intoxication—Potential Implication of Sirtuins date: 2020-05-05 words: 13430 flesch: 26 summary: Thus, it would be worthwhile to go the road of optimizing fucoidan effects by enhancing the efficaciousness of its derivatives. An interesting consideration is that it is possible to modify fucoidan derivatives to modulate fucoidan effects. keywords: activity; antioxidant; brain; cells; damage; disease; effects; expression; figure; fucoidan; function; injury; levels; liver; mice; mitochondrial; molecular; neurons; protein; sirt3; stress; stroke; study; treatment cache: cord-305240-r6i7d06v.txt plain text: cord-305240-r6i7d06v.txt item: #113 of 161 id: cord-308946-5flw7xk4 author: Kreiner, Jenny title: Saposhnikoviae divaricata: a phytochemical, pharmacological, and pharmacokinetic review date: 2017-04-30 words: 5001 flesch: 35 summary: Anti-inflammatory effects of SD chromones were revealed in arthritic rats, including significant decline in the arthritis score for pain and swelling, with a reduction of the inflammatory cytokines levels, although suppression of the tumor necrosis factor (TNF) α and IL-1β was only observed in rats treated with higher dose of SD [21] . SD chromones and anomalin are highly effective against acute and chronic inflammation. keywords: anomalin; cells; chromones; compounds; coumarins; divaricata; effects; mg·kg; pain; studies cache: cord-308946-5flw7xk4.txt plain text: cord-308946-5flw7xk4.txt item: #114 of 161 id: cord-310663-504p29hv author: Gambardella, Jessica title: Arginine and Endothelial Function date: 2020-08-06 words: 7203 flesch: 14 summary: Both clinical and preclinical studies are examined, analyzing the effects of arginine supplementation in hypertension, ischemic heart disease, aging, peripheral artery disease, and diabetes mellitus. L-arginine, hereinafter referred to as arginine, is a semi-essential or conditionally essential amino acid, since it can be synthetized by healthy individuals but not by preterm infants On these grounds, based on the positive effects of arginine on endothelial function, we can also speculate that arginine supplementation could be helpful, while not being harmful, for contrasting endothelial dysfunction in COVID-19 patients. keywords: administration; arginase; arginine; cardiovascular; diabetes; disease; dysfunction; effects; endothelial; heart; hypertension; insulin; nitric; oxide; patients; study; supplementation cache: cord-310663-504p29hv.txt plain text: cord-310663-504p29hv.txt item: #115 of 161 id: cord-310883-t5r4xqj3 author: Grundler, Franziska title: Interplay between oxidative damage, the redox status, and metabolic biomarkers during long-term fasting date: 2020-08-25 words: 4007 flesch: 35 summary: Proceedings of the 30 national academy of sciences Obesity and impaired metabolic health in 32 patients with COVID-19 Alternate day fasting improves physiological and molecular markers of aging in 36 healthy, non-obese humans Determining how best to support overweight adults to adhere to lifestyle change: protocol 39 for the SWIFT study The predictive power of the 41 microbiome exceeds that of genome-wide association studies in the discrimination of 42 complex human disease Spectrophotometric assays for 44 measuring redox biomarkers in blood Fasting therapy-an expert panel update of the 2002 48 consensus guidelines Safety, health 51 improvement and well-being during a 4 to 21-day fasting period in an observational study 52 including 1422 subjects 1 (2020a) Influence of Long-Term Fasting on Unravelling the health effects of 4 fasting: a long road from obesity treatment to healthy life span increase and improved 5 cognition Intermittent fasting with or without 7 exercise prevents weight gain and improves lipids in diet-induced obese mice Exercise Elicit Sexual-Dimorphic and Tissue-Specific Adaptations in Diet-Induced Obese Mice Increasing oxidative stress with progressive 13 hyperlipidemia in human: relation between malondialdehyde and atherogenic index Scavenging effect of methanolic extracts of peanut hulls on free-radical and 16 active-oxygen species Personalized nutrition by prediction of glycemic responses Metabolomics analysis 21 reveals the association between lipid abnormalities and oxidative stress, inflammation, 22 fibrosis and Nrf2 dysfunction in aristolochic acid-induced nephropathy • Long-term fasting increases the antioxidant capacity and decreases oxidative damage • It improves the metabolic health status • High TBARS levels at baseline limit the LDL reduction during long-term fasting • The antioxidant status is related with the lipid lowering effect of long-term fasting ☐ Subjects were excluded when they had a predefined 19 contraindication to fasting as described in the guidelines of fasting therapy (Wilhelmi de 20 Toledo et al., 2013) like cachexia, anorexia nervosa, advanced kidney, liver or 21 cerebrovascular insufficiency, dementia or other chronic psychiatric diseases, as well as 22 pregnant or lactating women. keywords: antioxidant; fasting; levels; lipid; metabolic; redox; scavenging; status; study; term cache: cord-310883-t5r4xqj3.txt plain text: cord-310883-t5r4xqj3.txt item: #116 of 161 id: cord-313971-czcs1y9w author: Zhao, Yang title: Airborne Microorganisms From Livestock Production Systems and Their Relation to Dust date: 2014-04-16 words: 15185 flesch: 34 summary: Concentrations of airborne microorganisms and dust in livestock production systems have been investigated in previous studies (Kim et al., 2008; Radon et al., 2002; Zhao et al., 2011a) . The effect of feeding management on airborne microorganism concentration has not been extensively studied. keywords: airborne; animal; bacteria; biological; concentrations; decay; deposition; dust; effect; efficiency; et al; factors; houses; humidity; infection; livestock; microbial; microorganisms; particles; pig; production; samplers; sampling; size; studies; survival; systems; temperature; transmission; virus cache: cord-313971-czcs1y9w.txt plain text: cord-313971-czcs1y9w.txt item: #117 of 161 id: cord-316181-ccauw70y author: Yang, Fude title: Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology date: 2017-05-16 words: 5736 flesch: 29 summary: Autophagy: process and function Autophagy modulation as a potential therapeutic target for diverse diseases The role of autophagy in cancer: therapeutic implications The dual role of autophagy in cancer Role of autophagy in aging Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD) Assessment of the effects of Radix Bupleuri and vinegarbaked Radix Bupleuri on cytochrome 450 activity by a six-drug cocktail approach Effect of saikosaponins and extracts of vinegar-baked Bupleuri Radix on the activity of -glucuronidase Saikosaponin a functions as anti-epileptic effect in pentylenetetrazol induced rats through inhibiting mTOR signaling pathway Saikosaponin-a Attenuates Oxidized LDL Uptake and Prompts Cholesterol Efflux in THP-1 Cells Saikosaponin C induces endothelial cells growth, migration and capillary tube formation A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent Anthelmintic activity of saikosaponins a and d from radix bupleuri against Dactylogyrus spp. The results showed that both raw and processed Radix Bupleuri showed liver protective effects against CCl 4 induced liver injury, and the vinegar-baked Radix Bupleuri exerted better effects than that of raw Radix Bupleuri keywords: activity; bupleuri; bupleurum; cancer; cells; chinese; effects; liver; radix; radix bupleuri; rats; saikosaponins; ssd cache: cord-316181-ccauw70y.txt plain text: cord-316181-ccauw70y.txt item: #118 of 161 id: cord-316992-fe5u2oi0 author: Nirk, Eliise Laura title: Hydroxychloroquine in rheumatic autoimmune disorders and beyond date: 2020-07-26 words: 10130 flesch: 27 summary: They showed that CQ could inhibit endosomal TLR signalling after stimulation with nucleic acids at concentration too low to influence the endosomal pH. Under those conditions, CQ blocks endosomal TLR activation by directly interacting with TLR ligands, such as nucleic acids, which changes the nucleic acid secondary structure and prevents their binding to endosomal TLRs (Macfarlane & Manzel, 1998; Ku znik et al, 2011) . In this context, CQ and HCQ decrease replication of viruses such as dengue virus (DENV2), chikungunya virus, hepatitis A and C virus, influenza A virus, Zika virus, severe acute respiratory syndrome coronavirus (SARS-CoV) and Borna disease virus in cellular models (Bishop, 1998; Gonzalez-Dunia et al, 1998; Keyaerts et al, 2004; Vincent et al, 2005; Blanchard et al, 2006; De Clercq, 2006; Eng et al, 2006; Di Trani et al, 2007; Sourisseau et al, 2007; Khan et al, 2010; Ashfaq et al, 2011; Boonyasuppayakorn et al, 2014; Farias et al, 2015; Delvecchio et al, 2016; Shiryaev et al, 2017) . keywords: activation; autophagy; cancer; cells; chloroquine; cytokines; diseases; drugs; effects; endosomal; et al; hcq; hydroxychloroquine; inhibition; levels; lupus; patients; production; response; signalling; syndrome; treatment; tumour cache: cord-316992-fe5u2oi0.txt plain text: cord-316992-fe5u2oi0.txt item: #119 of 161 id: cord-317250-a5ni1s9e author: Jackson, Ronald S. title: Wine, food, and health date: 2020-04-10 words: 19845 flesch: 40 summary: Even dietary flavonoid supplements (one of the benefits of wine consumption) can be detrimental, if taken in excess (Skibola and Smith, 2003) . As the sections below demonstrate, moderate, daily, wine consumption can have health benefits for the majority of people. keywords: acetaldehyde; acid; action; activity; addition; alcohol; alcohol consumption; antioxidant; benefits; beverages; blood; brain; cancer; cells; consumption; content; disease; effects; et al; ethanol; food; gastric; headache; health; histamine; human; intake; levels; liver; metabolism; oxidation; phenolics; plasma; potential; presence; production; release; resveratrol; risk; studies; study; tract; uptake; wine; wine consumption; wine phenolics cache: cord-317250-a5ni1s9e.txt plain text: cord-317250-a5ni1s9e.txt item: #120 of 161 id: cord-319646-6cex9gid author: Wu, Guoyao title: Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health date: 2020-02-18 words: 21604 flesch: 29 summary: The content of crude protein, amino acids, creatine, carnosine, anserine, and 4-hydroxyproline in beef and plant-source foods Adapted from Wu et al. (2016) , Wu et al. (2020) , and Hou et al. (2019) CP crude protein (6.25 × N%), OH-Pro 4-hydroxyproline are active in physical exercise (Rogerson 2017 ). For example, we found the half-lives of free 4-hydroxyproline in the blood of 8-and 160-day-old pigs are 46.2 ± 2.8 and 60.5 ± 3.3 min (mean ± SEM, n = 6), respectively, as determined by intravenous administration of 4-hydroxyproline (50 mg/kg BW) and the single exponential model of its pharmacokinetics (Wu et al. 2007 ). keywords: acids; administration; adult; alanine; amino; anserine; beef; bile; brain; carnosine; cells; collagen; concentrations; creatine; day; dietary; effects; et al; glycine; health; histidine; humans; hydroxyproline; hyp; liver; muscle; oral; plasma; protein; rats; supplementation; synthesis; taurine; tissues; wu et cache: cord-319646-6cex9gid.txt plain text: cord-319646-6cex9gid.txt item: #121 of 161 id: cord-320053-uceukiie author: Jones, Arwel Wyn title: Chapter 15 Exercise, Immunity, and Illness date: 2019-12-31 words: 19366 flesch: 19 summary: Despite the interest of the dentistry field in the role of AMPs in oral health and infection, (Putsep et al., 2002; Tanida et al., 2003; Tao et al., 2005; Dale et al., 2006) , the relationship of AMPs with exercise-induced immune dysfunction is yet to be explored conclusively (Davison et al., 2009) . However, it is reasonable to suggest that an airway inflammatory response partly accounts for the increases in AMPs identified immediately following prolonged exercise (Davison et al., 2009) . keywords: activity; amps; athletes; blood; cells; changes; effects; et al; exercise; function; gleeson; human; immunity; infection; lymphocytes; mucosal; neutrophil; nieman et; pathogens; prolonged; response; risk; salivary; siga; stress; studies; symptoms; system; tract; training; type; uri; urti; vivo; walsh et cache: cord-320053-uceukiie.txt plain text: cord-320053-uceukiie.txt item: #122 of 161 id: cord-320172-qw47pf9r author: Greaves, Peter title: VII Digestive System 1 date: 2000-12-31 words: 47447 flesch: 33 summary: It has been suggested from studies of the effects of anticancer compounds on neoplastic colonic cells that intestinal cells may possess inherent protective properties in the form of an accelerated efflux pump which can serve to protect them from potentially damaging agents (Klohs and Steinkampf, 1986) . A histochemical study Role of intestinal metaplasia in the histogenesis of gastric carcinoma Colorectal mucin histochemistry in health and disease: A critical review Uptake of particulate and soluble antigens in the small intestines of the rat Chemical colitis due to endoscopic cleaning solutions: A mimic of pseudomembranous colitis Pathology of Domestic Animals Intestinal accumulation of urea in germ-free animals: A factor in caecal enlargement Digestive enzymes in the parotid and submandibular glands of mammals Morphologishe Veränderungen der Magenmukosa von Ratten nach chronischer Antazidagabe Enteric viruses of non human primates Increased accumulation of sulfated glycoaminoglycans in cultures of human fibroblasts from phenytoin-induced gingival overgrowth New insights into the stem cells and the precursors of gastric epithelium Colonic lymphoid-glandular complex (microbursa): Nature and morphology Lymphoid tissue and lymphoid-glandular complexes of the colon: Relation to diverticulosis Histology of salivary gland infarction in the dog Adrenergic factors involved in the control of crypt cell proliferation in jejunum and descending colon of mouse Pill esophagitis Immunogold localization of ingested kidney bean (Phaseolus vugaris) lectins in epithelial cells of the rat small intestine Epithelial dysplasia of the rabbit colon induced by degraded carrageenan Hyperkeratinization and hyperplasia of the forestomach epithelium in vitamin A deficient rats Intrinsic resistance of colon tumors to anthrapyrazoles and antracyclines may be linked with a detoxification mechanism of intestinal cells (Abstract No. 1040) keywords: acid; activity; administration; agents; animals; cells; changes; chronic; colon; colonic; crypt; damage; differences; disease; dogs; drugs; effects; epithelium; et al; factor; features; forestomach; form; gastric; gastric mucosa; gastrointestinal; glands; glandular; goblet cells; growth; high; human; hyperplasia; increase; inflammation; inflammatory; intestine; laboratory; lesions; lymphocytes; lymphoid; man; metaplasia; mice; mouse; mucins; mucosa; non; number; oral; presence; rats; result; rodents; salivary; secretion; species; stomach; studies; study; surface; tissue; tract; treatment; ulceration; ulcers cache: cord-320172-qw47pf9r.txt plain text: cord-320172-qw47pf9r.txt item: #123 of 161 id: cord-320591-re99v1qt author: Le, Thanh Ninh title: Bioactive Compounds and Bioactivities of Brassica oleracea L. var. Italica Sprouts and Microgreens: An Updated Overview from a Nutraceutical Perspective date: 2020-07-27 words: 8198 flesch: 30 summary: Agriculture (Polnohospodárstvo) Response surface optimization and identification of isothiocyanates produced from broccoli sprouts Free radical scavenging, antiproliferative activities and profiling of variations in the level of phytochemicals in different parts of broccoli (Brassica oleracea italica) Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract Optimisation of enzymatic production of sulforaphane in broccoli sprouts and their total antioxidant activity at different growth and storage days Comparative Study of Predominant Phytochemical Compounds and Proapoptotic Potential of Broccoli Sprouts and Florets Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells Effect of broccoli sprouts on thyroid function, haematological, biochemical, and immunological parameters in rats with thyroid imbalance Antiproliferative Effect of Bioaccessible Fractions of Four Brassicaceae Microgreens on Human Colon Cancer Cells Linked to Their Phytochemical Composition Sorting out the value of cruciferous sprouts as sources of bioactive compounds for nutrition and health Phenolic acids: Natural versatile molecules with promising therapeutic applications Effect of bioaccessibility of phenolic compounds on in vitro anticancer activity of broccoli sprouts Influence of Sodium and Maturity Stage on the Antioxidant Properties of Cauliflower and Broccoli Sprouts Phenolic profile and antioxidant activity in selected seeds and sprouts Energy Regulated Nutritive and Antioxidant Properties during the Germination and Sprouting of Broccoli Sprouts (Brassica oleracea var. It could be summarized that glucosinolates and related compounds are the major group of phytochemicals investigated in broccoli sprouts and microgreens, although phenolic compounds have also been analyzed in many studies ( Figure 2 ). keywords: activity; antioxidant; broccoli; broccoli sprouts; cancer; cells; compounds; effects; food; glss; glucosinolates; health; microgreens; seedlings; sprouts; studies; sulforaphane; vivo cache: cord-320591-re99v1qt.txt plain text: cord-320591-re99v1qt.txt item: #124 of 161 id: cord-321590-8y1jy01c author: Hetland, Geir title: Can medicinal mushrooms have prophylactic or therapeutic effect against COVID‐19 and its pneumonic superinfection and complicating inflammation? date: 2020-07-29 words: 5620 flesch: 32 summary: Synergistic Effect of Combination With Interferon-Alpha in HepG2 2.2.15 Isolation, identification and function of a novel anti-HSV-1 protein from Grifola frondosa Antiviral properties of polysaccharides from Agaricus brasiliensis in the replication of bovine herpesvirus 1 Antiherpetic activity of an Agaricus brasiliensis polysaccharide, its sulfated derivative and fractions In vivo anti-herpes simplex activity of a sulfated derivative of Agaricus brasiliensis mycelial polysaccharide Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71 Antiviral properties of basidiomycetes metabolites In vitro anti-influenza virus activity of Agaricus brasiliensis KA21 Hericium erinaceus polysaccharide facilitates restoration of injured intestinal mucosal immunity in Muscovy duck reovirus-infected Muscovy ducklings Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro study An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice An extract of the mushroom Agaricus blazei Murill protects against lethal septicemia in a mouse model of fecal peritonitis Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up The role of gut microbiota in sepsis Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains Agaricus blazei hot water extract shows anti quorum sensing activity in the nosocomial human pathogen Pseudomonas aeruginosa Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis Evaluation of adjuvant activity of fractions derived from Agaricus blazei, when in association with the recombinant LiHyp1 protein, to protect against visceral leishmaniasis Effect of mushroom Agaricus blazei on immune response and development of experimental cerebral malaria Extraction, identification and antimicrobial activity of a new furanone, grifolaone A, from Grifola frondosa Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus Vitro and in vivo inhibition of Helicobacter pylori by ethanolic extracts of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes) Isolation, purification and physicochemical properties of polysaccharide from fruiting body of Hericium erinaceus and its effect on colonic health of mice Royal Sun Medicinal Mushroom Agaricus Brasiliensis (Higher Basidiomycetes) and the Attenuation of Pulmonary Inflammation Induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota Agaricus brasiliensis KA21 may prevent diet-induced nash through its antioxidant, anti-inflammatory, and anti-fibrotic activities in the liver Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats Erinacine A-enriched Hericium erinaceus mycelia promotes longevity in Drosophila melanogaster and aged mice Antitumor beta glucan from the cultured fruit body of Agaricus blazei Host-mediated antitumor effect of grifolan NMF-5N, a polysaccharide obtained from Grifola frondosa Glucan-induced enhancement of host resistance to selected infectious diseases Protective effect of betaglucan against systemic streptococcus pneumoniae infection in mice Coimmunization of Agaricus blazei Murill extract with hepatitis B virus core protein through DNA vaccine enhances cellular and humoral immune responses Extract from Agaricus blazei Murill can enhance immune responses elicited by DNA vaccine against foot-andmouth disease Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts Interactions of Toll-like receptors with fungi Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells Pattern recognition receptors and inflammation The crosstalk between TLR2 and NOD2 in Aspergillus fumigatus keratitis Syk-dependent glycolytic reprogramming in dendritic cells regulates IL-1β production to β-glucan ligands in a TLR-independent manner hBD-1: a novel beta-defensin from human plasma Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells Defensins: Transcriptional regulation and function beyond antimicrobial activity The polar high molecular weight fraction of the Agaricus blazei Murill extract, AndoSan™, reduces the activity of the tumor-associated protease, legumain, in RAW 264.7 cells The medicinal and antitumor mushroom Agaricus blazeii Murill activates NF-kappaB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity Polysaccharide Agaricus blazei Murill stimulates myeloid derived suppressor cell differentiation from M2 to M1 type, which mediates inhibition of tumour immune-evasion via the Toll-like receptor 2 pathway Enteroviruses: A gut-wrenching game of entry, detection, and evasion Cytokine immunopathogenesis of enterovirus 71 brain stem encephalitis Herpes simplex virus evasion of early host antiviral responses Muscovy duck reovirus infection disrupts the composition of intestinal microbiota in muscovy ducklings Viral exploitation and subversion of the immune system through chemokine mimicry A review of human diseases caused or exacerbated by aberrant complement activation Complement in the pathogenesis of Alzheimer's disease In a randomized clinical study (RCT), multiple myeloma patients undergoing high-dose chemotherapy and given add-on placebo-controlled treatment with the AbMbased Andosan™ for 2 months, were found to have the following immunomodulatory effects 12 : Reduced IL-1ra levels in plasma and increased T regulatory cells indicating anti-inflammatory effect, and increased plasmacytoid DC in blood and increased expression of genes in bone marrow aspirate at end of study vs before for KIRs and MHC antigens, the latter being important for antigen presentation. keywords: abm; agaricus; andosan; blazei; cells; disease; effect; extract; immune; infection; mushroom; patients; virus cache: cord-321590-8y1jy01c.txt plain text: cord-321590-8y1jy01c.txt item: #125 of 161 id: cord-322279-6ffnejwj author: Kwon, Seungwon title: Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: A Narrative Review date: 2020-07-17 words: 4612 flesch: 41 summary: Based on this guideline, herbal medicine treatment has been used in more than 50% of confirmed patients with COVID-19 in J o u r n a l P r e -p r o o The search keywords included SSHT, constituents of SSHT, and antiviral effect. keywords: covid-19; disease; effect; hepatitis; liver; medicine; patients; ssht; symptoms; treatment; virus cache: cord-322279-6ffnejwj.txt plain text: cord-322279-6ffnejwj.txt item: #126 of 161 id: cord-323467-ifwjvvjj author: Beaver, Annabelle title: Invited review: A systematic review of the effects of early separation on dairy cow and calf health date: 2019-07-31 words: 10076 flesch: 42 summary: Of the 70 included articles, 7 (3 single-herd and 4 multi-herd studies) addressed respiratory health in dairy calves. It is important to recognize that a large proportion of dairy calves left with the dam fail to nurse within 6 h after parturition (46% of calves born to dams of second or higher parity; Edwards and Broom, 1979) . keywords: articles; calf; calves; colostrum; contact; cow; dairy; dam; disease; effect; et al; health; herd; management; risk; studies; suckling cache: cord-323467-ifwjvvjj.txt plain text: cord-323467-ifwjvvjj.txt item: #127 of 161 id: cord-323647-q67fa0m3 author: Misra, Durga Prasanna title: Benefits and adverse effects of hydroxychloroquine, methotrexate and colchicine: searching for repurposable drug candidates date: 2020-09-02 words: 6153 flesch: 32 summary: In this French RCT (the BBQ trial), patients with recurrent pregnancy loss shall be treated with HCQ 400 mg daily or placebo starting pre-conception until the 10 th week of pregnancy, with the objective of assessing whether treatment improves pregnancy outcomes in such patients [18] . THerapy in ST-Segment Elevation MYocardial InfarctionS: a randomized double-blind, placebocontrolled trial (TETHYS Trial) Low-dose methotrexate for the prevention of atherosclerotic events Colchicine as an anti-inflammatory and cardioprotective agent Colchicine revisited The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation Colchicine improves survival, left ventricular remodeling, and chronic cardiac function after acute myocardial infarction Effects of colchicine on atherosclerotic plaque stabilization: a multimodality imaging study in an animal model Colchicine reduces platelet aggregation by modulating cytoskeleton rearrangement via inhibition of cofilin and LIM domain kinase 1 Can the thiol/disulfide imbalance be a predictor of colchicine resistance in familial mediterranean fever? Colchicine therapy and plaque stabilization in patients with acute coronary syndrome: a CT coronary angiography study Effect of shortterm colchicine treatment on endothelial function in patients with coronary artery disease Colchicine as a novel therapy for suppressing chemokine production in patients with an acute coronary syndrome: a pilot study The Low Dose Colchicine after Myocardial Infarction (LoDoCo-MI) study: a pilot randomized placebo controlled trial of colchicine following acute myocardial infarction The effect of low-dose colchicine in patients with stable coronary artery disease: the LoDoCo2 trial rationale, design, and baseline characteristics COLIN trial: value of colchicine in the treatment of patients with acute myocardial infarction and inflammatory response Efficacy and safety of low-dose colchicine after myocardial infarction Role of colchicine in stroke prevention: an updated meta-analysis The role of colchicine in treating postoperative and post-catheter ablation atrial fibrillation Comparative transcriptome analysis to elucidate the therapeutic mechanism of colchicine against atrial fibrillation The effect of colchicine on the echocardiographic constrictive physiology after coronary artery bypass graft surgery Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease Effects of colchicine on renal fibrosis and apoptosis in obstructed kidneys Effectiveness of colchicine therapy in 4 cases of retroperitoneal fibrosis associated with autoinflammatory diseases Use of colchicine to prevent recurrence of ear keloids. keywords: colchicine; covid-19; disease; drugs; effects; hcq; hydroxychloroquine; methotrexate; patients; placebo; risk; treatment; trial cache: cord-323647-q67fa0m3.txt plain text: cord-323647-q67fa0m3.txt item: #128 of 161 id: cord-325779-pxnl4wgc author: Liang, Yu-lei title: Thoughts on the effects of moxa smoke in the epidemic prevention: 关于艾烟防疫作用的思考 date: 2020-07-17 words: 2559 flesch: 42 summary: Et Vant Effects of folium artemisiae argyi burning products on monoamine neurotransmitters contents in brain of senescence-accelerated mouse P8 Effect of moxa products after burning on SOD， MDA and GSH-Px in the brain of senescence accelerated mice Effect of long-term intervention of moxa smoke with different concentrations on vWF, ox-LDL in rats blood serum Effects of moxa smoke extract on neuronal apoptosis and its mechanism Clinical trial proves that moxa smoke fumigation achieves the same or even better effect as compared with the room air disinfection and ultraviolet disinfection and this method is not influenced by temperature and humidity keywords: disinfection; effect; fumigation; moxa; moxibustion; smoke cache: cord-325779-pxnl4wgc.txt plain text: cord-325779-pxnl4wgc.txt item: #129 of 161 id: cord-327045-hn8pmcto author: Li, Yao title: Quercetin, Inflammation and Immunity date: 2016-03-15 words: 5377 flesch: 35 summary: In the Suihua area of northern China, quercetin intake was reported to be 4.37 mg/day, where the main food sources of flavonol was apples (7.4%), Quercetin (C15H10O7) is an aglycone, lacking an attached sugar. In the Suihua area of northern China, quercetin intake was reported to be 4.37 mg/day, where the main food sources of flavonol was apples (7.4%), followed by potatoes (3.9%), lettuce (3.8%) and oranges (3.8%) keywords: anti; cells; day; dietary; effect; function; human; immune; inflammation; intake; quercetin; sources cache: cord-327045-hn8pmcto.txt plain text: cord-327045-hn8pmcto.txt item: #130 of 161 id: cord-327521-g5vefajw author: Spisni, Enzo title: Antioxidant, Anti-Inflammatory, and Microbial-Modulating Activities of Essential Oils: Implications in Colonic Pathophysiology date: 2020-06-10 words: 9207 flesch: 30 summary: Anti-Cancer Drugs Geraniol and geranyl acetate induce potent anticancer effects in colon cancer Colo-205 cells by inducing apoptosis, DNA damage and cell cycle arrest Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells Polyamine metabolism and gene methylation in conjunction with one-carbon metabolism Thymol elicits HCT-116 colorectal carcinoma cell death through induction of oxidative stress Cinnamaldehyde affects the biological behaviour of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signalling pathway Novel cinnamaldehyde-based aspirin derivatives for the treatment of colorectal cancer Dual acid-responsive micelle-forming anticancer polymers as new anticancer therapeutics Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells Geraniol, a component of plant essential oils, sensitizes human colonic cancer cells to 5-fluorouracil treatment Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts Identification of genetic susceptibility loci for colorectal tumors in a genome-wide meta-analysis Red meat and colon cancer: A review of mechanistic evidence for heme in the context of risk assessment methodology Alcohol, smoking and the risk of premalignant and malignant colorectal neoplasms The gut microbiota, bacterial metabolites and colorectal cancer Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis Molecular genetics of colorectal cancer Clinical management of hereditary colorectal cancer syndromes Balancing the efficacy and toxicity of chemotherapy in colorectal cancer Pharmacologic resistance in colorectal cancer: A review Carvacrol inhibits proliferation and induces apoptosis in human colon cancer cells. keywords: activities; activity; antioxidant; bacteria; cancer; carvacrol; cell; cinnamaldehyde; colitis; colon; effects; eos; geraniol; human; microbiota; molecules; oils; studies; thymol; vitro cache: cord-327521-g5vefajw.txt plain text: cord-327521-g5vefajw.txt item: #131 of 161 id: cord-328814-s3963anw author: XU, Jing title: Exploration on the feasibility of moxibustion in prevention and treatment of COVID-19 from the perspective of modern medical mechanism date: 2020-06-11 words: 3457 flesch: 40 summary: Feasibility of yiqi xuanbi decoction in treating pulmonary fibrosis after new crown pneumonia Effects of Moxibustion of Feishu (BL13) and Gaohuangshu (BL43) on expression of E-cad Gene in lung epithelial cells in BLMA5-induced pulmonary fibrosis rats Regulation of E-cad, α-SMA and vimentin through moxibustion at Feishu and Gaohuangshu of pulmonary fibrosis rats Combined with Qiangli Zhike Capsule (强力止咳宁胶囊) on Chronic Bronchitis Clinical observation of yang-supplementing fire moxibustion for chronic obstructive pulmonary disease in stable stage Contribution of physicians in the south of the Five Ridges in acupuncture and moxibustion treatment of plague and cholera Clinical observation of moxibustion in the treatment of 79 cases of epidemic hemorrhagic fever Observation on the effect of moxibustion on renal function of epidemic hemorrhagic fever 20 cases of condyloma acuminatum treated with moxibustion Retrospective analysis of Mr. Xie Xiliang's medical records accumulated in 30 years on direct moxibustion for treating hepatitis B Clinical observation of treating refractory pulmonary tuberculosis with garlic moxibustion A pneumonia outbreak associated with a new coronavirus of probable bat origin Nine cases of the chronic stage of SARS treated by moxibustion Clinical observation of heat-sensitive moxibustion treatment for coronavirus disease Discussion on the effect pathways of preventing and treating coronavirus disease 2019 by acupuncture and moxibustion from the regulation of immune inflammatory response On TCM diagnosis and treatment program of Coronavirus Disease 2019 in Hunan province by national TCM Master XIONG Jibo Discussion on traditional Chinese medicine prevention and treatment strategies of Coronavirus Disease 2019 (COVID-19) from the perspective of cold-dampness pestilence The role of immunological testing and intervention in reproductive medicine: A fertile collaboration? Analysis of novel coronavirus pneumonia related blood test indexes in 80 cases Clinical characteristics and laboratory results of 3 886 patients with fever and cough Therapeutic effect of ginger warming and moxibustion on children's cough variant asthma and its influence to on immune function Regulation effect of moxibustion with small moxa-cone about the size of a wheat grain at zusanli point on cellular immune function in elderly bedridden patients Clinical study on the effect of Du-moxibustion therapy on the symptom and levels of serum supplement C3 and C4 in yang-deficiency subjects The effect of moxibustion shenque point on immune function of digestive tract cancer patients undergoing chemotherapy Effect of moxibustion on survival status and nutritional metabolic factor in tumor-bearing rats with gastric cancer Effect of solar-term moxibustion on hemorheology and immune function in patients with subhealth status of yang deficiency Molecular pathways in virus-induced cytokine production Therapeutic strategies for COVID-19 based on its pathophysiological mechanisms Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Effect of electroacupuncture stimulation of Feishu (BL 13) on lung index, serum and lung IL-10 and and TNF-α levels in mice with viral pneumonia Effect of mild moxibustion on bacterial infection and inflammation in mice and related autophagy mechanism Effect of moxibustion on body weight and peripheral and cerebral cortical IL-6 and IL-10 levels in fatigue rats Mechanism study on NIK/NF-κB/VEGF pathway, anti-inflammation and analgesia in RA treated with moxibustion Effect of moxibustion on TGF-β1, HIF-1α and VEGF levels in patients with rheumatoid arthritis (RA) Effects of moxa-moxibustion plus infrared illumination on community acquired pneumonia and immune function Thinking of the effect of integrated Chinese and western medicine on COVID-19 Dynamic changes of serum SARS-coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge keywords: body; covid-19; disease; effect; function; moxibustion; patients; treatment; yang cache: cord-328814-s3963anw.txt plain text: cord-328814-s3963anw.txt item: #132 of 161 id: cord-331270-12zx0o2p author: Rico, Timóteo Matthies title: Use of Text Messaging (SMS) for the Management of Side Effects in Cancer Patients Undergoing Chemotherapy Treatment: a Randomized Controlled Trial date: 2020-09-30 words: 5889 flesch: 46 summary: Results showed intervention group patients experienced fewer side effects compared to the control group in cycle 1 (p < 0.05), in general. The degree of satisfaction that cancer patients express about the information they receive has been associated with positive health outcomes, specifically regarding quality of life, performance status, side effects, and psychological well-being [18] . keywords: cancer; chemotherapy; cycle; effects; group; intervention; messages; patients; text; treatment cache: cord-331270-12zx0o2p.txt plain text: cord-331270-12zx0o2p.txt item: #133 of 161 id: cord-331633-ix5un6c9 author: Teixeira, Maria C. title: Nanomedicines for the Delivery of Antimicrobial Peptides (AMPs) date: 2020-03-20 words: 9145 flesch: 27 summary: Furthermore, nanomaterials can be used for antimicrobial drug delivery, and the incorporation of antimicrobial nanomaterials in medical devices and implants can prevent microbial adhesion and infection Antimicrobial drug delivery using polymeric NPs offers several advantages: (i) structural stability in biological fluids and under harsh and various conditions for preparation; (ii) precisely tuneable properties, such as size, zeta-potentials, and drug release profiles, by manipulating polymer lengths, surfactants, and organic solvents used for NP preparation [67] , and (iii) facile and versatile surface functionalization for conjugating drugs and targeting ligands [68] . keywords: activity; amps; antibiotics; bacteria; delivery; development; drug; effects; lipid; nanomaterials; nanoparticles; nps; peptide; properties; resistance; systems; use cache: cord-331633-ix5un6c9.txt plain text: cord-331633-ix5un6c9.txt item: #134 of 161 id: cord-333119-vu4qbcy1 author: Zhang, Xiao-rui title: The Important Role of Volatile Components From a Traditional Chinese Medicine Dayuan-Yin Against the COVID-19 Pandemic date: 2020-09-25 words: 5875 flesch: 27 summary: It has various pharmacological potential such as antibacterial, antiviral, and immune-enhancing properties which can be exploited in the treatment of acute upper respiratory tract infection (Zhang et al., 2013) . Furthermore, lopinavir and many interferons, especially interferon beta, have moderate effects against SARS-COV in vitro and can be used in combination with ribavirin (Chen et al., 2004; Chan et al., 2013) . keywords: acute; antibacterial; components; covid-19; dayuan; disease; effects; et al; injury; lung; medicine; oil; patients; prevention; treatment; yin cache: cord-333119-vu4qbcy1.txt plain text: cord-333119-vu4qbcy1.txt item: #135 of 161 id: cord-333672-ef53l283 author: Potter, Gregory D. M. title: The Future of Shift Work: Circadian Biology Meets Personalised Medicine and Behavioural Science date: 2020-08-07 words: 10157 flesch: 33 summary: Front Nutr DOI: 10.3389/fnut.2020.00116 sha: doc_id: 333672 cord_uid: ef53l283 Shift work is commonplace in modern societies, and shift workers are predisposed to the development of numerous chronic diseases. Disruptions to the circadian systems of shift workers are considered important contributors to the biological dysfunction these people frequently experience. keywords: breakfast; effects; energy; health; light; melatonin; period; phase; schedules; shift; shift workers; sleep; studies; time; timing; tre; workers cache: cord-333672-ef53l283.txt plain text: cord-333672-ef53l283.txt item: #136 of 161 id: cord-335024-0klf75qr author: Saponaro, Federica title: An Update on Vitamin D Metabolism date: 2020-09-08 words: 9512 flesch: 37 summary: Novel ligands and structural insights Epigenome-wide effects of Vitamin D and their impact on the transcriptome of human monocytes involve CTCF Structural aspects of Vitamin D endocrinology Regulation of the vitamin D receptor gene by environment, genetics and epigenetics Epigenetics, cellular memory and gene regulation Nutrigenomics of vitamin D KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells Molecular endocrinology of vitamin D on the epigenome level Structural considerations of vitamin D signaling Minireview: Vitamin D receptor: New assignments for an already busy receptor Extraskeletal actions of vitamin D Key Vitamin D Target Genes with Functions in the Immune System Vitamin D's Effect on Immune Function Modulation of inflammatory and immune responses by vitamin D Vitamin D action: Lessons from VDR and Cyp27b1 null mice Vitamin D Supplementation for the Prevention of Acute Respiratory Tract Infection: A Randomized, Double-Blinded Trial among Young Finnish Men Vitamin D status has a linear association with seasonal infections and lung function in British adults Serum 25-hydroxyvitamin D and the incidence of acute viral respiratory tract infections in healthy adults Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis The association between vitamin D deficiency and community-acquired pneumonia Vitamin D supplementation to prevent acute respiratory tract infections: Systematic review and meta-analysis of individual participant data A pneumonia outbreak associated with a new coronavirus of probable bat origin Letter: Covid-19, and vitamin D COVID-19 and vitamin D-Is there a link and an opportunity for intervention? Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths Letter: Evidence for Extrarenal Generation of 1,25-Dihydroxyvitamin D Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review Regulation of Renal and Extrarenal 1α-Hydroxylase Vitamin D Metabolism Revised: Fall of Dogmas The measurement of vitamin D metabolites: Part I-Metabolism of vitamin D and the measurement of 25-hydroxyvitamin D. Hormones Hereditary hypercalcemia caused by a homozygous pathogenic variant in the cyp24a1 gene: A case report and review of the literature Epimers of vitamin d: A review Progress of liquid chromatography-mass spectrometry in measurement of vitamin D metabolites and analogues Measuring 25-hydroxyvitamin D in a clinical environment: Challenges and needs 25-Hydroxyvitamin D assays: The quest for accuracy Analysis of vitamin D metabolic markers by mass spectrometry: Current techniques, limitations of the gold standard method, and anticipated future directions Mass spectrometric profiling of Vitamin D metabolites beyond 25-hydroxyVitamin D Candidate reference measurement procedures for serum 25-hydroxyvitamin D3and 25-hydroxyvitamin D2by using isotope-dilution liquid chromatography-tandem mass spectrometry Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 using isotope-dilution liquid chromatography-tandem mass spectrometry Standardizing vitamin D assays: The way forward NHANES monitoring of serum 25-hydroxyvitamin D: A roundtable summary UK Food Standards Agency Workshop Consensus Report: The choice of method for measuring 25-hydroxyvitamin D to estimate vitamin D status for the UK National Diet and Nutrition Survey Vitamin D metabolite profiling using liquid chromatography-tandem mass spectrometry (LC-MS/MS) Simultaneous profiling of vitamin D metabolites in serum by supercritical fluid chromatography-tandem mass spectrometry Vitamin D Binding Protein: A Historic Overview The multifunctional properties and characteristics of vitamin D-binding protein Vitamin D2 is much less effective than vitamin D3 in humans The free hormone hypothesis: A physiologically based mathematical model Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells Vitamin D and DBP: keywords: activity; calcium; cells; cyp27b1; cyp2r1; effects; hydroxylase; hydroxyvitamin; levels; metabolism; receptor; regulation; risk; role; system; vdr; vitamin; vitamin d cache: cord-335024-0klf75qr.txt plain text: cord-335024-0klf75qr.txt item: #137 of 161 id: cord-337856-xaxxewb6 author: Trump, Cary E. title: Behavior Momentum Theory and Humans: A Review of the Literature date: 2020-09-30 words: 6210 flesch: 20 summary: In their study, all three participants demonstrated greater response persistence in the context associated richer reinforcement schedule when reinforcement was disrupted. Overall, the review discovered 73% of the included experiments indicated problem behavior responses persisted greater in rich compared to lean schedules. keywords: behavior; effect; experiments; extinction; persistence; reinforcement; response; review cache: cord-337856-xaxxewb6.txt plain text: cord-337856-xaxxewb6.txt item: #138 of 161 id: cord-338778-l53i77rn author: Kim, Hong-bumm title: Do expectations of future wealth increase outbound tourism? Evidence from Korea date: 2012-01-04 words: 5923 flesch: 39 summary: Wealth effects may appear insignificant and vary depending on the characteristics of the demand, product, and asset, and caution should be employed when drawing on the effect of unrealized wealth. Although the current study utilized Korean data to overcome the limitations originating from the 'aggregation economy,' the theory of wealth effect on consumption has been supported and empirically validated to a significant extent, especially by studies using micro data (Poterba, 1988) . keywords: assets; consumption; demand; effect; housing; income; market; outbound; stock; tourism; travel; wealth cache: cord-338778-l53i77rn.txt plain text: cord-338778-l53i77rn.txt item: #139 of 161 id: cord-339082-8gogju5n author: Swire-Thompson, Briony title: Searching for the Backfire Effect: Measurement and Design Considerations date: 2020-09-02 words: 7179 flesch: 34 summary: There is currently a debate in the literature as to whether backfire effects exist at all, as recent studies have failed to find the phenomenon, even under theoretically favorable conditions. We suggest that backfire effects are not a robust empirical phenomenon, and more reliable measures, powerful designs, and stronger links between experimental design and theory could greatly help move the field ahead. keywords: backfire; belief; correction; effect; familiarity; item; misinformation; participants; post; pre; studies; truth; worldview cache: cord-339082-8gogju5n.txt plain text: cord-339082-8gogju5n.txt item: #140 of 161 id: cord-339293-7ks3bopm author: Nejatifard, Marzieh title: Probable Positive Effects of the Photobiomodulation as an Adjunctive Treatment in COVID-19: A Systematic Review date: 2020-10-12 words: 4588 flesch: 47 summary: Previous studies have shown the advantages of the PBM including anti-inflammatory effects and acceleration of the wound healing (10) . Keywords included the PBM and related terms, lung inflammation, and COVID-19 -related signs. keywords: ards; covid-19; disease; effects; inflammation; laser; lung; papers; patients; pbm cache: cord-339293-7ks3bopm.txt plain text: cord-339293-7ks3bopm.txt item: #141 of 161 id: cord-339475-okw6la2b author: None title: Chapter 11 Health effects date: 2005-12-31 words: 3091 flesch: 44 summary: However, none of the harmful components mentioned above exists in ambient particles at sufficiently high concentration levels to cause a specific disease. Ambient particles are harmful when their concentration exceeds a certain limit; epidemiological studies have indicated a strong association of increases in human morbidity and mortality rates with increased concentrations of ambient particles in a certain size fraction (Wilson and Spengler, 1996; Vedal, 1997) . keywords: agents; air; cause; disease; effects; exposure; particles; region cache: cord-339475-okw6la2b.txt plain text: cord-339475-okw6la2b.txt item: #142 of 161 id: cord-340101-n9zqc1gm author: Bzdok, Danilo title: The Neurobiology of Social Distance date: 2020-06-03 words: 9249 flesch: 38 summary: Analyses of information flow in social networks suggest that sources outside the 50 closest friendships offer few benefits [72] . Regular interaction with different people at the periphery of social networks can give rise to heightened perceived social and emotional fulfillment in ways that act as psychological buffers [24] , although this might depend on personality or social style [74] . keywords: brain; cortex; effects; friends; health; humans; individuals; isolation; life; loneliness; monkeys; network; people; prefrontal; relationships; size; social; stress; study cache: cord-340101-n9zqc1gm.txt plain text: cord-340101-n9zqc1gm.txt item: #143 of 161 id: cord-340882-why0t9ld author: Carneiro, Lara title: The Effects of Exclusively Resistance Training-Based Supervised Programs in People with Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials date: 2020-09-15 words: 8051 flesch: 43 summary: To achieve optimal outcomes and decrease dropouts, the evidence also indicates that physiotherapists and qualified exercise professionals should lead and supervise physical exercise programs Additionally, incorporating a motivational component into exercise interventions for depression may be needed to decrease dropouts. keywords: analysis; depression; effects; exercise; group; meta; people; physical; resistance; studies; symptoms; training cache: cord-340882-why0t9ld.txt plain text: cord-340882-why0t9ld.txt item: #144 of 161 id: cord-341720-qwdjb7vk author: Jukic, Igor title: Strategies and Solutions for Team Sports Athletes in Isolation due to COVID-19 date: 2020-04-24 words: 4267 flesch: 35 summary: A major consideration when training athletes in home isolation is compliance, especially regarding the intensity and volume of exercise. A major consideration when training athletes in home isolation is compliance, especially regarding the intensity and volume of exercise. keywords: athletes; body; effects; exercise; isolation; muscle; performance; protein; sports; strength; training cache: cord-341720-qwdjb7vk.txt plain text: cord-341720-qwdjb7vk.txt item: #145 of 161 id: cord-343303-by0b3gy0 author: Nishinari, Katsuyoshi title: Molar mass effect in food and health date: 2020-09-03 words: 21135 flesch: 45 summary: In amylose gelation, the plateau value increased with increasing molar mass as shown in 35 Fig.10A , while in β-glucan gelation, the plateau value seemed to decrease with increasing molar 36 mass as shown in Fig.10B , though for slow gelling samples with higher molar mass did not reach 37 the plateau within 100 h. The apparent inconsistency between Fig.11A and Fig.11B , that the 38 apparent plateau modulus increases with increasing MW in the former (amylose) while it is 39 smaller for higher MW in the latter (β-glucan), originates from the non-equilibrium nature of these 40 apparent plateau moduli. For 20 a higher starch concentration (15% maize starch), the rate constant k of retrogradation kinetic 21 the rate constant) was found to decrease with increasing molar mass of the added guar gum (0.5%) 23 for higher molar mass than 10.1 ×10 5 (G6), however, the lower molar mass guar gum, G7 and 24 G8 were found to promote the retrogradation ( Fig 23A) . keywords: addition; amylose; carrageenan; concentration; content; decrease; effect; food; gelation; gels; guar; gum; increase; kda; modulus; molar mass; polysaccharides; proteins; rate; shear; solution; starch; temperature; transition; viscosity; water; weight cache: cord-343303-by0b3gy0.txt plain text: cord-343303-by0b3gy0.txt item: #146 of 161 id: cord-344498-mwgccbfo author: Casado-Aranda, Luis-Alberto title: Analysis of the Scientific Production of the Effect of COVID-19 on the Environment: A Bibliometric Study date: 2020-11-03 words: 5784 flesch: 34 summary: This study is not only a first in the evolution of COVID-19 research from the specific perspective of environmental studies, but will be of extreme utility for information professionals to disseminate objective and quality coverage on the effects of the virus on the environment. Thus the co-word analysis applied text-mining techniques to the titles, abstracts, and keywords leading to the design, based on fundamental bibliometric indicators such as the number of publications, of a strategic diagram illustrating the main themes of interest related to the issue of environment in COVID-19 research. keywords: air; analysis; covid-19; effects; environmental; et al; information; pandemic; quality; research; science; smart; studies; study cache: cord-344498-mwgccbfo.txt plain text: cord-344498-mwgccbfo.txt item: #147 of 161 id: cord-344988-09vpehvf author: Overbeck, Silke title: Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases date: 2008-02-05 words: 7948 flesch: 36 summary: Free Radic Zinc supplementation reconstitutes the production of interferon-α by leukocytes from elderly persons Dysregulation between TH1 and TH2 T cell subpopulations in the elderly Zinc, insulin and diabetes Changes in serum selenium, copper, zinc levels and Cu/Zn ratio in patients with pulmonary tuberculosis during therapy Zinc deficiency and supplementation in HIV/AIDS Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T--lymphocyte proliferation and nuclear protein kinase C Hyperzincuria in individuals with insulin-dependent diabetes mellitus: concurrent zinc status and the effect of high-dose zinc supplementation A zinc dependent epitope of the molecule of thymulin, a thymic hormone Effect of zinc and vitamin A supplementation on antibody responses to a pneumococcal conjugate vaccine in HIV-positive injection drug users: a randomized trial Interference in the development of a secondary immune response in mice by zinc deprivation: persistence of effects Effects of zinc supplementation in patients with type 1 diabetes The role of assembly in insulin's biosynthesis Zinc and the gene Beneficial effects of oral zinc supplementation on the immune response of old people Plasma zinc concentrations are depressed during the acute phase response in children with falciparum malaria Transcriptional regulation of the mouse metallothionein-I gene by heavy metals Bioavailability of zinc in several sources of zinc oxide, zinc sulfate, and zinc metal Effect of oral zinc supplementation on the cell mediated immunity in lepromatous leprosy Role of zinc in insulin biosynthesis: some possible zinc-insulin interactions in the pancreatic B-cell Zinc in developmental biology: the role of metal dependent transcription regulation Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania Zinc and the risk for infectious disease An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection Regeneration of T-cell helper function in zinc-deficient adult mice Interrelationships between zinc and immune function Zinc deficiency and the immune function Reprogramming of the immune system during zinc deficiency Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of Bcl-2/Bax ratio Treatment of acrodermatitis enteropathica with zinc sulphate Effect of severe zinc deficiency on activity of intestinal disaccharidases and 3-hydroxy-3-methy-glutaryl coenzyme A reductase in the rat In vitro activity of zinc salts against human rhinoviruses Serum zinc/copper ratio in subtypes of leprosy and effect of oral zinc therapy on reactional states Transport of electrolytes, water, and glucose in zinc deficiency Kinetic aspects of compartmental storage and secretion of insulin and zinc A randomised controlled trial of oral zinc on the immune response to tuberculosis in HIV-infected patients Zinc as a second messenger of mitogenic induction. Effects on diadenosine tetraphosphate (Ap4A) and DNA synthesis Flow cytometric measurement of labile zinc in peripheral blood mononuclear cells Correlation between zinc status and immune function in the elderly Signal transduction in monocytes: the role of zinc ions Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease Inhibition of HIV-1 infection by zinc group metal compounds Effect of intragastric pH on the absorption of oral zinc acetate and zinc oxide in young healthy volunteers Zinc aspartate in vivo and in vitro modulation of reactive oxygen species production by human neutrophils and monocytes Zinc in the treatment of acute diarrhea: current status and assessment Efficacy of zinc against common cold viruses: an overview Zinc-altered immune function Zinc and the common cold: a meta-analysis revisited A meta--analysis of zinc salts lozenges and the common cold Intestinal and systemic immune responses to an oral cholera toxoid B subunit whole-cell vaccine administered during zinc supplementation A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxycillin and clarithromycin increases the cure rate of Helicobacter pylori infection Copper and zinc inhibit the metabolism of prostaglandin by the human uterus The effect of zinc supplementation on the treatment of chronic hepatitis C patients with interferon and ribavirin Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides Zinc ions inhibit replication of rhinoviruses The impaired immune response to diphtheria vaccination in elderly chronic hemodialysis patients is related to zinc deficiency Transgenic copper/zinc superoxide dismutase modulates susceptibility to type 1 diabetes The mechanism of the antiherpetic activity of zinc sulphate The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children Identification of SLC39A4, a gene involved in acrodermatitis enteropathica Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute--phase response Absorption of zinc in acrodermatifis enteropathica Dietary factors influencing zinc absorption keywords: cells; deficiency; effect; function; immune; infection; oral; patients; production; response; studies; study; supplementation; therapy; treatment; zinc; zinc supplementation cache: cord-344988-09vpehvf.txt plain text: cord-344988-09vpehvf.txt item: #148 of 161 id: cord-345696-gwbi6nlt author: Álvarez-Castro, José M. title: Gene–Environment Interaction in the Era of Precision Medicine – Filling the Potholes Rather Than Starting to Build a New Road date: 2020-10-06 words: 6218 flesch: 26 summary: To this regard, it has become particularly opportune that an elusive implementation of models of genetic interactions, even claimed to be beyond reach, has recently been attained, enabling genetic interaction (epistasis) and genotype frequencies correlation (linkage disequilibrium) to be disentangled (Alvarez-Castro and Crujeiras, 2019). The present paper meets those demands by providing mathematical developments that implement classical models of genetic effects and bring them up to date with the prospects current available data bestow. keywords: effects; environment; gene; interaction; models; risk cache: cord-345696-gwbi6nlt.txt plain text: cord-345696-gwbi6nlt.txt item: #149 of 161 id: cord-347644-4qenzjiu author: Shorter, John R. title: A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size date: 2019-03-15 words: 6977 flesch: 38 summary: Litter size is moderately heritable, and maternal effects account for the majority of explained variation To estimate founder strain effects on litter size, we used a Bayesian regression model that decomposes the phenotypic variation in the diallel into genetic and parent-of-origin contributions (Lenarcic et al. 2012 ). Under the general effects, we see significant positive additive effects on average litter size from B6, NOD, and NZO and significant negative additive effects on litter size from CAST, PWK, and WSB strain dosages. keywords: average; collaborative; cross; diallel; effects; et al; litter; litter size; model; pups; sex; size; strain cache: cord-347644-4qenzjiu.txt plain text: cord-347644-4qenzjiu.txt item: #150 of 161 id: cord-348106-agwdmtug author: Shankar, Venkatesh title: Omnichannel Marketing: Are Cross-Channel Effects Symmetric? date: 2020-09-07 words: 10139 flesch: 45 summary: In such a theory, channel efforts make significant Our research also offers scope for the development of a theory about the relative magnitudes of channel effects on shopping outcomes. Because channel effects occur in the presence of advertising, we need to control advertising effects. keywords: advertising; agents; center; channel; cross; data; effects; efforts; influence; marketing; model; outcomes; shopping; web cache: cord-348106-agwdmtug.txt plain text: cord-348106-agwdmtug.txt item: #151 of 161 id: cord-348994-ly2fop7d author: Faustini, Annunziata title: Attributable Risk to Assess the Health Impact of Air Pollution: Advances, Controversies, State of the Art and Future Needs date: 2020-06-23 words: 8164 flesch: 31 summary: 2. They can observe the same relationship under different circumstances, such as seasons, and in different populations thus making causality a more plausible interpretation of any possible association, providing that heterogeneity has been controlled for or assessed; 3. Even a weak effect of air pollution on health will constitute an important public health problem, since a unique characteristic of air pollution exposure is its ubiquity for large populations. The discussion began with Kunzli's observations [45] about the double action of air pollution on both the long-term underlying diseases and the short term risk of death: the author identified four different combinations: (a) air pollution increases the risks of both underlying diseases, leading to frailty, and of short-term mortality among the frail; (b) air pollution increases the risk of chronic diseases but is unrelated to the timing of death; (c) air pollution is unrelated to chronic diseases but short term exposure increases mortality among the frail; (d) neither underlying chronic disease nor death is related to air pollution exposure. keywords: air pollution; assessment; effects; exposure; health; health effects; impact; mortality; particulate; population; risk; studies; study; term; term exposure cache: cord-348994-ly2fop7d.txt plain text: cord-348994-ly2fop7d.txt item: #152 of 161 id: cord-349807-ar77cnsa author: Rouadi, Philip W. title: Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD) date: 2020-10-05 words: 8643 flesch: 23 summary: Taken together, controlled airway exposure studies to ambient pollutants in healthy individuals show small but significant negative health effects whereas exposure studies in allergic patients support the role of pollutants in increasing atopic airway hypersensitivity. The role of the reactive oxygen species and oxidative stress in the pathomechanism of the agerelated ocular diseases and other pathologies of the anterior and posterior eye segments in adults House dust mite -induced asthma causes oxidative damage and DNA double-strand breaks in the lungs International expert consensus on the management of allergic rhinitis (AR) aggravated by air pollutants Impact of air pollution on patients with AR: current knowledge and future strategies Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern Immunomodulation and T Helper TH1/TH2 response polarization by CeO2 and TiO2 nanoparticles Association of indoor dampness and molds with rhinitis risk: a systematic review and meta-analysis Rhinitis symptoms and asthma among parents of preschool children in relation to the home environment in chongqing , China Long-term exposure to close-proximity air pollution and asthma and allergies in urban children PM 10, and children's respiratory symptoms and lung function in the PATY study Association between environmental factors and hospital visits among allergic patients: a retrospective study Science of the Total Environment Time-series studies on air pollution and daily outpatient visits for allergic rhinitis in Traffic-related air pollution and the development of asthma and allergies during the first 8 Years of life Air quality influences the prevalence of hay fever and sinusitis Traffic-related air pollution in relation to respiratory symptoms , allergic sensitisation and lung function in schoolchildren Upper airway inflammation and respiratory symptoms in domestic waste collectors An association between fine particles and asthma emergency department visits for children in Seattle Asthma and air pollutants: a time series study Environmental and occupational allergies Residential proximity to major roadways is associated with increased prevalence of allergic respiratory symptoms in children Meta-analysis of air pollution exposure association with allergic sensitization in European birth cohorts The effects of air pollution on the development of atopic disease Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis Expression of heme oxygenase-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps: modulation by cytokines Airborne fine particulate matter induces oxidative stress and inflammation in human nasal epithelial cells Diesel exhaust as a model xenobiotic in allergic inflammation Phase 3, single-center, sequential and parallel group, double-blind, randomized study evaluating the efficacy and safety of Fexofenadine Hydrochloride 180 mg (Allegra/Telfast) versus placebo in subjects suffering from Allergic Rhinitis with symptoms aggravated in presence of pollutants: analysis of individual symptom scores Low-level ozone has both respiratory & systemic effects in African-American adolescents with asthma despite asthma controller therapy Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone Ozone-induced inflammation is attenuated with multiday exposure Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies Airway cells from atopic asthmatics exposed to ozone display an enhanced innate immune gene profile Breath markers of oxidative stress and airway inflammation in seasonal allergic rhinitis Oxidative stress status and plasma trace elements in patients with asthma or allergic rhinitis Total antioxidant status and oxidative stress and their relationship to total IgE levels and eosinophil counts in children with allergic rhinitis Plasma paraoxonase activity and oxidative stress and their relationship to disease severity in children with allergic rhinitis A new oxidative stress marker for thiol-disulphide homeostasis in seasonal allergic rhinitis Oxidative stress in the airways of children with asthma and allergic rhinitis Heme oxygenase (HO)-1 is upregulated in the nasal mucosa with allergic rhinitis Overexpression of the superoxide anion and NADPH oxidase isoforms 1 and 4 (NOX1 and NOX4) in allergic nasal mucosa Influence of desloratadine on selected oxidative stress markers in patients between 3 and 10 years of age with allergic perennial rhinitis Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae Genetic susceptibility to the respiratory effects of air pollution Effects of glutathione Stransferase gene polymorphisms and antioxidant capacity per unit albumin on the pathogenesis of chronic obstructive pulmonary disease Novel antioxidant approaches to the treatment of upper airway inflammation Effects of Nacetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial Antioxidant intake and allergic disease in children Effect of silymarin in the treatment of allergic rhinitis N-Acetylcysteine combined with home based physical activity: effect on health related quality of life in stable COPD patients-a randomised controlled trial Air pollutant-mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway Potential role of antioxidant food supplements, preservatives and colorants in the pathogenesis of allergy and asthma Effects of antioxidant supplements and nutrients on patients with asthma and allergies N-acetylcysteine exerts therapeutic action in a rat model of allergic rhinitis Short-term effects of low-level air pollution on respiratory health of adults suffering from moderate to severe asthma Air pollution and asthma control in the epidemiological study on the genetics and environment of asthma Associations of PM10 and airborne iron with respiratory health of adults living near a steel factory Increased asthma medication use in association with ambient fine and ultrafine particles Increased levels of exhaled carbon monoxide in bronchiectasis: a new marker of oxidative stress Realistic indoor nanoaerosols for a human exposure facility Effects on heart rate variability by artificially generated indoor nano-sized particles in a chamber study Health effects of a mixture of indoor air volatile organics , their ozone oxidation products , and stress Sensory and cognitive effects of acute exposure to hydrogen sulfide 1998 equivalence of sensory responses to single and mixed volatile organic compounds at equimolar concentrations Exposure of humans to a volatile organic mixture . keywords: air; airway; antioxidant; asthma; cells; disease; effects; exposure; health; human; indoor; infection; model; ozone; particles; patients; pollutants; pollution; response; stress; studies cache: cord-349807-ar77cnsa.txt plain text: cord-349807-ar77cnsa.txt item: #153 of 161 id: cord-350973-rprrkr37 author: Ahmad, Md Faruque title: An updated knowledge of Black seed (Nigella sativa Linn): Review of phytochemical constituents and pharmacological properties date: 2020-09-19 words: 6616 flesch: 37 summary: It has been reported in a randomised controlled trial J o u r n a l P r e -p r o o f of 108 patients that the consumption of N. sativa seed for 2 months can lower the BP in the mildly hypertensive patients (Dehkordi and Kamkhah, 2008; Fallah Huseini et al., 2013) . In a comparative study between N. sativa seeds and a triple therapy using clarithromycin, amoxicillin, and omeprazole, it was reported N. sativa was clinically significant against Helicobacter pylori (H. pylori). keywords: activity; antioxidant; cells; effects; et al; extract; n. sativa; nigella; nigella sativa; oil; properties; sativa; seed; thymoquinone cache: cord-350973-rprrkr37.txt plain text: cord-350973-rprrkr37.txt item: #154 of 161 id: cord-351932-dn60t7qa author: Salehi, Bahare title: Dioscorea Plants: A Genus Rich in Vital Nutra-pharmaceuticals-A Review date: 2019 words: 9790 flesch: 29 summary: Dioscorea alata L. Dioscorea alata L. is one of the most popular varieties of yams. The study revealed that the anti-MI mechanism of Dioscorea saponins is related not only to the enzymatic antioxidant, such as GPx and CAT but also to nonenzymatic antioxidants and its effect on myocardial histology (87) . keywords: activities; activity; antioxidant; cells; compounds; dioscorea; effect; extract; food; inflammatory; mice; nipponica; potential; rhizomes; saponins; species; steroidal; study; treatment; tubers; yam cache: cord-351932-dn60t7qa.txt plain text: cord-351932-dn60t7qa.txt item: #155 of 161 id: cord-353815-w35spqqt author: Huan, Yuchen title: Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields date: 2020-10-16 words: 12289 flesch: 27 summary: Archiv Activity and characterization of a pH-sensitive antimicrobial peptide Influence of pH on the activity of thrombin-derived antimicrobial peptides Effects of antimicrobial peptides on growth performance and small intestinal function in broilers under chronic heat stress Grouper (Epinephelus coioides) antimicrobial peptide epinecidin-1 exhibits antiviral activity against foot-andmouth disease virus in vitro A cancer vaccine based on the marine antimicrobial peptide pardaxin (GE33) for control of bladder-associated tumors Acquired resistance to the rice blast in transgenic rice accumulating the antimicrobial peptide thanatin Characterization and antimicrobial evaluation of SpPR-AMP1, a proline-rich antimicrobial peptide from the mud crab The vast structural diversity of antimicrobial peptides Predicting the minimal inhibitory concentration for antimicrobial peptides with rana-box domain The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding Conformational fine-tuning of pore-forming peptide potency and selectivity Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening Comparative analysis of two attacin genes from Hyphantria cunea The human anionic antimicrobial peptide dermcidin induces proteolytic defence mechanisms in Staphylococci Antimicrobial peptides: possible anti-infective agents Dalbavancin and telavancin in the treatment of infective endocarditis: a literature review Antimicrobial peptides: application informed by evolution Transcriptome analysis of Streptococcus pneumoniae treated with the designed antimicrobial peptides Intracellular targeting mechanisms by antimicrobial peptides Diptericinlike protein: an immune response gene regulated by the anti-bacterial gene induction pathway in drosophila De novo generation of short antimicrobial peptides with simple amino acid composition The antimicrobial peptides and their potential clinical applications Exploring small cationic peptides of different origin as potential antimicrobial agents in aquaculture Interactions of the antimicrobial peptide nisin Z with conventional antibiotics and the use of nanostructured lipid carriers to enhance antimicrobial activity Two optimized antimicrobial peptides with therapeutic potential for clinical antibiotic-resistant Staphylococcus aureus Membrane active antimicrobial peptides: translating mechanistic insights to design Mechanism of antifungal activity of antimicrobial peptide APP, a cell-penetrating peptide derivative, against Candida albicans: intracellular DNA binding and cell cycle arrest Membrane interactions of proline-rich antimicrobial peptide, Chex1-Arg20, multimers Effects of the peptide H-OOWW-NH2 and its derived lipopeptide C12-OOWW-NH2 on controlling of citrus postharvest green mold Implicit membrane investigation of the stability of antimicrobial peptide β-barrels and arcs Control of sour rot in citrus fruit by three insect antimicrobial peptides Effects of rabbit sacculus rotundus antimicrobial peptides on the intestinal mucosal immunity in chickens Effect of an antifungal peptide from oyster enzymatic hydrolysates for control of gray mold (Botrytis cinerea) on harvested strawberries Biological activity and structural aspects of PGLa interaction with membrane mimetic systems Membrane pore-formation correlates with the hydrophilic angle of histidine-rich amphipathic peptides with multiple biological activities The first antimicrobial peptide from sea amphibian Regulation of cell division in E. coli Antimicrobial packaging based on ε-polylysine bioactive film for the control of mycotoxigenic fungi in vitro and in bread Nucleation and growth of pores in 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) / cholesterol bilayer by antimicrobial peptides melittin, its mutants and cecropin P1 In vitro and MD simulation study to explore physicochemical parameters for antibacterial peptide to become potent anticancer peptide Antimicrobial peptides of the vaginal innate immunity and their role in the fight against sexually transmitted diseases The value of antimicrobial peptides in the age of resistance Influence of self-assembly on the performance of antimicrobial peptides Kappacin, a novel antibacterial peptide from bovine milk Temporins, small antimicrobial peptides with leishmanicidal activity The host antimicrobial peptide Bac71-35 binds to bacterial ribosomal proteins and inhibits protein synthesis keywords: acid; activity; amino; amps; antibacterial; application; binding; cationic; cell; design; effect; et al; example; food; gram; human; inhibit; mechanism; membrane; motif; peptides; potential; properties; protein; research; residues; resistance; structure; virus cache: cord-353815-w35spqqt.txt plain text: cord-353815-w35spqqt.txt item: #156 of 161 id: cord-354044-3ugc7odq author: Salazar-Gómez, Anuar title: The potential role of sesquiterpene lactones isolated from medicinal plants in the treatment of the metabolic syndrome – A review date: 2020-09-16 words: 9409 flesch: 29 summary: Normalization of blood pressure Hong et al., 1999 Hong et al., , 2005 Reduction (#); increment (); thiobarbituric acid reactive substances (TBARS); reduced glutathione (GSH); superoxide dismutase (SOD); catalase (CAT); glutathione peroxidase (GPx); insulin resistance (IR); Toll-like receptor 4 (TLR4); c-Jun N-terminal kinases (JNK); interleukin 6 (IL-6); monocyte chemoattractant protein 1 (MCP-1); Apolipoprotein C3 (APOC3); AMP-activated protein kinase (AMPK); peroxisome proliferator-activated receptors a and g (PPARa/g); nuclear factor kappa B (NF-kB); transforming growth factor beta (TGF-b1); fibronectin (FN); glucose-6-phosphatase (G6Pase); glucokinase (GK); cyclooxygenase 2 (COX-2); interferon-gamma (IFN-g); tumor necrosis factor a (TNF-a); angiotensin I-converting enzyme (ACE). The guaianolide cumambrin A (21) (Fig. 2) , isolated from Chrysanthemum boreale (Makino) Makino, has shown a pharmacological effect on the normalization of blood pressure in spontaneously hypertensive rats (Hong et al., 1999) . keywords: activity; anti; blood; cells; compounds; diabetes; effects; et al; glucose; inhibition; insulin; lactone; levels; mets; rats; sesquiterpene; slns; studies; syndrome; toxicity; treatment cache: cord-354044-3ugc7odq.txt plain text: cord-354044-3ugc7odq.txt item: #157 of 161 id: cord-354459-90bvoy08 author: Zhang, Fan title: Research on the Applications of Calcium Propionate in Dairy Cows: A Review date: 2020-08-03 words: 7287 flesch: 34 summary: The role of TCA cycle anaplerosis in ketosis and fatty liver in periparturient dairy cows Addition of calcium propionate to finishing lamb diets Effect of calcium propionate and sorghum level on lamb performance The effect of calcium propionate supplementation on performance, meat quality, and mRNA expression of finishing steers fed a high-concentrate diet Silage review: Foodborne pathogens in silage and their mitigation by silage additives Patulin-producing molds in corn silage and high moisture corn and effects of patulin on fermentation by ruminal microbes in continuous culture Airborne molds and mycotoxins associated with handling of corn silage and oilseed cakes in agricultural environment The effects of buffered propionic acid-based additives alone or combined with microbial inoculation on the fermentation of high moisture corn and whole-crop barley Effects of calcium propionate on the fermentation quality and aerobic stability of alfalfa silage Effect of calcium propionate and water activity on growth and aflatoxins production by Aspergillus flavus Effects of four short-chain fatty acids or salts on the dynamics of nitrogen transformations and intrinsic protease activity of alfalfa silage Proteomics and metabolomics characterizing the pathophysiology of adaptive reactions to the metabolic challenges during the transition from late pregnancy to early lactation in dairy cows Integration of metabolism and intake regulation: A review focusing on periparturient animals Prevalence of excessive negative energy balance in commercial United Kingdom dairy herds Impact of supplementing propylene glycol and calcium propionate to primiparous buffalo cows during the late gestation and early lactation period on reproductive performance and metabolic parameters Adipose tissue metabolism and production responses to calcium propionate and chromium propionate Nutrition, immune function and health of dairy cattle Effects of supplemental dietary energy source on feed intake, lactation performance, and serum indices of early-lactating Holstein cows in a positive energy balance Effects of dietary calcium propionate on growth performance and carcass characteristics of finishing lambs Propionate induces mRNA expression of gluconeogenic genes in bovine calf hepatocytes Biology of dairy cows during the transition period: The final frontier? Effects of calcium propionate supplementation on lactation performance, energy balance and blood metabolites in early lactation dairy cows Effects of dietary glucogenic precursors and fat on feed intake and carbohydrate status of transition dairy cows Blood parameters of lactating cows fed calcium salts as energetic source Calcium propionate increased milk parameters in Holstein cows Influence of calcium propionate on in vitro fermentation of sorghum-based diets Additive genetic and heterosis effects for milk fever in a population of Jersey, Holstein Ã� Jersey, and Holstein cattle under grazing conditions Epidemiology of subclinical hypocalcemia in early-lactation Holstein dairy cows: Effect of diet-induced negative energy balance on the feeding behavior of dairy cows Effect of subclinical and clinical hypocalcemia and dietary cation-anion difference on rumination activity in periparturient dairy cows Mycotoxins occurrence and fungal populations in different types of silages for dairy cows in Spain Elevating serotonin pre-partum alters the Holstein dairy cow hepatic adaptation to lactation Antifungal treatment of paper with calcium propionate and parabens: Short-term and long-term effects Conditioned place avoidance using encapsulated calcium propionate as an appetite suppressant for broiler breeders Calcium propionate supplementation improves development of rumen epithelium in calves via stimulating G protein-coupled receptors Effects of 3300 del A-1061 Ter BRCA1 frameshift mutation and calcium propionate on oxidative stress and breast carcinogenesis Influence of calcium propionate, water activity and storage time on mold incidence and aflatoxins production in broiler starter feed Sanitary dips with calcium propionate, calcium chloride, or a calcium amino acid chelate maintain quality and shelf stability of fresh-cut honeydew chunks A study of the decomposition of calcium propionate, using simultaneous TG-DTA Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance Effect of weak acid preservatives on growth of bakery product spoilage fungi at different water activities and pH values Effect of dietary calcium propionate on performance, hepatic enzyme activities and aflatoxin residues in broilers fed a diet containing low levels of aflatoxin B1 Response surface methodology-based optimization of decontamination conditions for Escherichia coli O157:H7 and Salmonella Typhimurium on fresh-cut celery using thermoultrasound and calcium propionate Effects of four short-chain fatty acids or salts on dynamics of fermentation and microbial characteristics of alfalfa silage Incorporation of Lactobacillus plantarum and zeolites in poultry feed can reduce aflatoxin B1 levels Effect of calcium propionate on the microstructure and pectin methy-lesterase activity in the parenchyma of fresh-cut Fuji apples The use of sourdough fermented by antifungal LAB to reduce the amount of calcium propionate in bread Symposium review: Transition cow calcium homeostasis-Health effects of hypocalcemia and strategies for prevention Effects of glucose, propionic acid, and nonessential amino acids on glucose metabolism and milk yield in Holstein dairy cows Whole-body glucose metabolism and mammary energetic nutrient metabolism in lactating dairy cows receiving digestive infusions of casein and propionic acid Whole-body propionate and glucose metabolism of multiparous dairy cows receiving folic acid and vitamin B12 supplements Temporal effects of ruminal infusion of propionic acid on hepatic metabolism in cows in the postpartum period keywords: acid; calcium; calcium propionate; cows; dairy; dairy cows; effects; feed; glucose; milk; production; propionate; propionic; rumen; silage cache: cord-354459-90bvoy08.txt plain text: cord-354459-90bvoy08.txt item: #158 of 161 id: cord-354651-bxm9yxjm author: Zeng, Yawen title: Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases date: 2020-03-30 words: 16017 flesch: 36 summary: Interestingly, the types of prevention and treatment of human chronic diseases by key functional components in barley grain were in order: β-glucans (16)>polyphenols (13)>arabinoxylan (7) = tocols (7)>phytosterols (5)>resistant starch (4), but GABA (13)>flavonoids (11)>SOD (8)>K-Ca (7) = vitamins (7)>tryptophan (3) in barley grains. More than 30 functional ingredients in barley grass can combat over 20 chronic diseases, and 15 functional ingredients in barley grains may prevent 11 chronic diseases [9] . keywords: acid; activity; antioxidant; arabinoxylan; barley; barley grains; barley β; cells; cholesterol; content; diet; diseases; effects; extract; food; gaba; glucan; glucose; grains; grass; health; homo; hulless; hulless barley; human; ingredients; mg/100; phytosterols; polyphenols; role; sapiens; starch; total cache: cord-354651-bxm9yxjm.txt plain text: cord-354651-bxm9yxjm.txt item: #159 of 161 id: cord-355873-e5cd4o0q author: Shah, Bakht Ramin title: Effects of prebiotic dietary fibers and probiotics on human health: With special focus on recent advancement in their encapsulated formulations date: 2020-06-23 words: 2835 flesch: -25 summary: Human vaccines & 848 immunotherapeutics Probiotics and prebiotics: present status and future perspectives on 850 metabolic disorders Akkermansia muciniphila is a promising probiotic Effect of probiotic supplementation on cognitive function and metabolic status in Alzheimer's disease: a randomized, double-blind and controlled trial Glucose-and lipid-related biomarkers are affected in healthy obese or hyperglycemic adults consuming a whole-grain pasta enriched in prebiotics and probiotics: a 12-week randomized controlled trial Probiotics and prebiotic fiber for constipation associated with Parkinson disease: an RCT Probiotication of cooked sausages employing agroindustrial coproducts as prebiotic co-encapsulant in ionotropic alginate-pectin gels Potential application of monoglyceride structured emulsions as delivery systems of probiotic bacteria in reduced saturated fat ice cream Prebiotic carbohydrates: effect on reconstitution, storage, release, and antioxidant properties of lime essential oil microparticles Improving quality parameters of functional strawberry juices: Optimization of prebiotic fiber enrichment and geraniol treatment Probiotics for infantile colic: a randomized, double-blind, placebo-controlled trial investigating Lactobacillus reuteri DSM 17938 Microencapsulation of a probiotic and prebiotic in alginate-chitosan capsules improves survival in simulated gastro-intestinal conditions The propre-save study: effects of probiotics and prebiotics alone or combined on necrotizing enterocolitis in very low birth weight infants Effects of probiotics on nonalcoholic fatty liver disease in obese children and adolescents Effect of prebiotic ingredients on the rheological properties and microstructure of reduced-sodium and low-fat meat emulsions Inulin-based emulsion-filled gel as a fat replacer in prebiotic-and PUFA-enriched dry fermented sausages The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: a double-blind, randomized trial Physicochemical changes and microbial inactivation after high-intensity ultrasound processing of prebiotic whey beverage applying different ultrasonic power levels Physicochemical characterization and potential prebiotic effect of whey protein isolate/inulin nano complex A double-blind, placebo-controlled study to assess the effect of a probiotic mixture on symptoms and inflammatory markers in women with diarrhea-predominant IBS key: cord-355873-e5cd4o0q authors: Shah, Bakht Ramin; Li, Bin; Al Sabbah, Haleama; Xu, Wei; Mraz, Jan title: Effects of prebiotic dietary fibers and probiotics on human health: With special focus on recent advancement in their encapsulated formulations date: 2020-06-23 journal: keywords: dietary; disease; effect; fiber; gut; health; inulin; microbiota; probiotic; trial cache: cord-355873-e5cd4o0q.txt plain text: cord-355873-e5cd4o0q.txt item: #160 of 161 id: cord-355935-psnqrdo2 author: Paez, Antonio title: A Spatio‐Temporal Analysis of the Environmental Correlates of COVID‐19 Incidence in Spain date: 2020-06-08 words: 8999 flesch: 47 summary: The classical SUR model without spatial effects (from here, SUR-SIM) is a stack of equations as follows: where y t = (y 1t , … , y Nt ) is a N × 1 vector, and in our case y st is the incidence ratio in the province s (s = 1, …, N) the day t (t = 1, …, T); X t is a N × When the null hypothesis is rejected, several alternative specifications have been proposed to include spatial effects (Anselin 1988) . keywords: analysis; covid-19; days; disease; effect; humidity; incidence; model; period; population; provinces; temperature; time; variables cache: cord-355935-psnqrdo2.txt plain text: cord-355935-psnqrdo2.txt item: #161 of 161 id: cord-356062-7q5n4t97 author: None title: Cumulative pharmacological activity index volumes 1-30 date: 2005-12-31 words: 6484 flesch: -24 summary: 29:99 activity in EBV assay system 29:99 11, 15, activity in EBV assay system 29:99 Abieta-8,11,13-triene-7o~,l Human melanoma 23:255 Human mesangial cell proliferation 30:308 in vitro Human monoblastic leukemia cells 30:498 effect of hydroxyurea (HU) 30:498 growth inhibition of 30:498 Human monoblastic leukemia U937 cells 30:498 growth inhibition of Human neuroblastoma nbla-N-5 cells tamoxifen activity against 12:390 Human neuroblastoma SH-SY-5Y cells 12:390 Human neutrophils 12:390 Human neutropil protein kinase C 12:389 Human onchocerciasis 12:9 ivermectin for Human papilloma virus 30:394 pathogenesis of 30:394 cause of hepatocellular carcinoma Human Papilloma virus (HPV) 23:97 Human papilloma virus type 11 30:406 microbicidal compound against Human papilloma virus type 40 30:406 microbicidal compound against 30:406 Human platelets 12:390 study of protein kinase C in 12:390 by staurosporine 12:390 Human rotavirus (HRV) 30:406,412 cause of dehydrating gastroenteritis 30:406 member of 30:406 reoviridae type of Human serotonin transporter gene (SLC6A4) 30:376 regulation of neuronal activity Human spermatozoa motility 21:675 Human synovial PLA2 25:697 inhibitor anti-glycemic effects 24:902-904 anti-hyperglycemic effects of -O-methyl-20-hydroxyecdysone activity in 29:28 pinnatasterone activity in 29:28 polypodine B 2-O-cinnamate activity in Muscarinic AchR antagonists 21:56 Muscarinic antagonist 22:19 Muscarinic receptor 21:95 Muscarinic receptor antagonists 22:734 Muscarinic-l,2-receptor 21:95 Muscle pain 24:898 aconitine for relieving activation effects of 24:906 medicinal uses of 24:906 protein kinase C activation effects 24:906 Muscular P-388 (murine lymphocytic leukemia) 30:588 activity of (-)-deoxypodophyllotoxin against 30:588 activity of (-)-yatein against P-388 lymphocytic leukemia cell 25:764 keywords: 29:720; 30:589; 30:815; acid; activity; agent; antitumor; assay system; bioassay; cell; ebv; effects; human; inhibitor; kinase; nh2; properties; protease; protein; receptor; role; type; tyr; use; virus cache: cord-356062-7q5n4t97.txt plain text: cord-356062-7q5n4t97.txt