# bib

id: cord-331045-i33nr27j
author: Addie, Diane D.
title: Feline coronavirus – that enigmatic little critter
date: 2003-11-13
extension: .txt
mime: text/plain
words: 1250
sentence: 40
flesch: 46
cache: cache/cord-331045-i33nr27j.txt
txt: txt/cord-331045-i33nr27j.txt
summary:
  Nevertheless, her results must be confirmed on larger numbers of cats, SAA levels should be studied in the many differential diagnoses of FIP and, of course, we need to understand whether and how acute phase proteins enable FCoV exposed cats to recover from the infection in order to ascertain if therein lies a potential for FIP treatment -and control of that critter. This is a question which constantly arises in real life, and Dr. Giordano is the first to present an answer: she found that there was a massive increase in serum amyloid A (SAA) compared with FCoV exposed cats.


id: cord-323932-l14sjufm
author: Ishida, T
date: 2004-02-25
extension: .txt
mime: text/plain
words: 1682
sentence: 64
flesch: 42
cache: cache/cord-323932-l14sjufm.txt
txt: txt/cord-323932-l14sjufm.txt
title:
  Use of recombinant feline interferon and glucocorticoid in the treatment of feline infectious peritonitis

summary:
  key: cord-323932-l14sjufm authors: Ishida, T; Shibanai, A; Tanaka, S; Uchida, K; Mochizuki, M title: Use of recombinant feline interferon and glucocorticoid in the treatment of feline infectious peritonitis date: 2004-02-25 journal: J Feline Med Surg DOI: 10.1016/j.jfms.2003.08.011 sha: doc_id: 323932 cord_uid: l14sjufm A total of 12 clinically ill cats previously diagnosed as feline infectious peritonitis (FIP) were treated with a combination of recombinant feline interferon and glucocorticoid. Summary A total of 12 clinically ill cats previously diagnosed as feline infectious peritonitis (FIP) were treated with a combination of recombinant feline interferon and glucocorticoid.


id: cord-335434-lgvoethn
author: Cannon, Martha .J.
date: 2005-02-12
extension: .txt
mime: text/plain
words: 1930
sentence: 70
flesch: 30
cache: cache/cord-335434-lgvoethn.txt
txt: txt/cord-335434-lgvoethn.txt
title:
  Cutaneous lesions associated with coronavirus-induced vasculitis in a cat with feline infectious peritonitis and concurrent feline immunodeficiency virus infection

summary:
  Value of a1-acid glycoprotein in the diagnosis of feline infectious peritonitis FIP-related disease An uncommon intestinal manifestation of feline infectious peritonitis: 26 cases (1986e1993) Systemic vascular lesions in feline infectious peritonitis Update on feline coronavirus disease Update on the pathobiology of vasculitis Cellular composition, coronavirus antigen expression and production of specific antibodies in lesions of feline infectious peritonitis Morphological features and development of granulomatous vasculitis in feline infectious peritonitis Polysystemic viral diseases: feline coronavirus Some aspects of humoral and cellular immunity in naturally occurring feline infectious peritonitis Immunologic phenomena in the effusive form of feline infectious peritonitis Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus Feline infectious peritonitis: a review of clinicopathological changes in 65 cases, and a critical assessment of their diagnostic value An appraisal of the value of laboratory tests in the diagnosis of feline infectious peritonitis Disseminated intravascular coagulation in experimentally induced feline infectious peritonitis. key: cord-335434-lgvoethn authors: Cannon, Martha .J.; Silkstone, Malcolm A.; Kipar, Anja M. title: Cutaneous lesions associated with coronavirus-induced vasculitis in a cat with feline infectious peritonitis and concurrent feline immunodeficiency virus infection date: 2005-02-12 journal: J Feline Med Surg DOI: 10.1016/j.jfms.2004.12.001 sha: doc_id: 335434 cord_uid: lgvoethn This report describes a clinical case of feline infectious peritonitis (FIP) with multisystemic involvement, including multiple nodular cutaneous lesions, in a cat that was co-infected with feline coronavirus and feline immunodeficiency virus.


id: cord-308557-mvu97jsu
author: Pesteanu-Somogyi, Loretta D.
title: Prevalence of feline infectious peritonitis in specific cat breeds()
date: 2005-07-01
extension: .txt
mime: text/plain
words: 2240
sentence: 81
flesch: 45
cache: cache/cord-308557-mvu97jsu.txt
txt: txt/cord-308557-mvu97jsu.txt
summary:
  Breed, sex and reproductive status of affected cats were compared to the general cat population and to mixed breed cats evaluated during the same period. Mixed breed cats of all hair lengths (domestic shorthair, mediumhair and longhair) were considered a single breed (termed 'mixed breed') for data analysis purposes.


id: cord-023034-j8zwcfys
author: Osterhaus, Albert D. M. E.
title: Feline Infectious Peritonitis Virus: II. Propagation in Suckling Mouse Brain
date: 2010-05-13
extension: .txt
mime: text/plain
words: 2275
sentence: 92
flesch: 35
cache: cache/cord-023034-j8zwcfys.txt
txt: txt/cord-023034-j8zwcfys.txt
summary:
  Table 1 Passage history of FIP virus (strain Dahlberg) in suckling mouse brain Support for this tentative classification has been obtained recently from neutralization and immunofluorescence studies showing an antigenic relationship between FIP virus and the coronavirus causing transmissible gastroenteritis (TGE) of swine (6, 8, 13) .


id: cord-329866-io9fvy58
author: Lorusso, Eleonora
date: 2019-08-31
extension: .txt
mime: text/plain
words: 2812
sentence: 83
flesch: 36
cache: cache/cord-329866-io9fvy58.txt
txt: txt/cord-329866-io9fvy58.txt
title:
  Discrepancies between feline coronavirus antibody and nucleic acid detection in effusions of cats with suspected feline infectious peritonitis

summary:
  Additional 13 samples presented FCoV antibody titres between 1:200 and 1:800, which are quite high for an enteric infection but cannot be considered enough high for a systemic infection. 1:1600 as cut-off (Fig. 1B) , 6 samples tested negative by both assays (no viral RNA and no FCoV antibodies), possibly accounting for diseases other than FIP, and 3 samples tested negative only by qRT-PCR, although they contained FCoV antibody titres between 1:3200 and 1:12,800, which were highly suggestive of FIP.


id: cord-324530-tac1unnp
author: André, Nicole M
date: 2019-06-26
extension: .txt
mime: text/plain
words: 2928
sentence: 135
flesch: 43
cache: cache/cord-324530-tac1unnp.txt
txt: txt/cord-324530-tac1unnp.txt
title:
  Distinct mutation in the feline coronavirus spike protein cleavage activation site in a cat with feline infectious peritonitis-associated meningoencephalomyelitis

summary:
  An update on feline infectious peritonitis: diagnostics and therapeutics An update on feline infectious peritonitis: virology and immunopathogenesis CNS disease in the cat: current knowledge of infectious causes Prevalence of diseases of the spinal cord of cats Fenner's veterinary virology Improving virus taxonomy by recontextualizing sequence-based classification with biologically relevant data: the case of the Alphacoronavirus 1 species Infectious diseases of the dog and cat A review of coronavirus infection in the central nervous system of cats and mice Immunocytochemical demonstration of feline infectious peritonitis virus within cerebrospinal fluid macrophages Practical overview of common infectious disease agents Hagan and Brunner's microbiology and infectious diseases of domestic animals Diagnosis and clinical signs of feline infectious peritonitis in the central nervous system A retrospective study of the neuropathology and diagnosis of naturally occurring feline infectious peritonitis Feline infectious peritonitis with neurologic involvement: clinical and pathological findings in 24 cats Feline infectious peritonitis with spinal cord involvement in two cats Clinicopathologic features and magnetic resonance imaging findings in 24 cats with histopathologically confirmed neurologic feline infectious peritonitis Mutation in spike protein cleavage site and pathogenesis of feline coronavirus Immunohistochemical studies on meningoencephalitis in feline infectious peritonitis (FIP) Spike protein fusion peptide and feline coronavirus virulence Significance of coronavirus mutants in feces and diseased tissues of cats suffering from feline infectious peritonitis Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis Acknowledgements We thank Wendy Wingate for help with sample collection, all members of the Whittaker lab for helpful comments and support, and Dr John Loftus for clinical consultation and critical reading of the manuscript. [1] [2] [3] It is the most common infectious disease of the central nervous system (CNS) of cats.


id: cord-287157-6rwevq39
author: Kiss, I.
date: 2004-02-25
extension: .txt
mime: text/plain
words: 3036
sentence: 118
flesch: 41
cache: cache/cord-287157-6rwevq39.txt
txt: txt/cord-287157-6rwevq39.txt
title:
  Disease outcome and cytokine responses in cats immunized with an avirulent feline infectious peritonitis virus (FIPV)-UCD1 and challenge-exposed with virulent FIPV-UCD8

summary:
  Cats that developed FIP had negligible or below normal IFNresponses, save cat 527 that showed slightly elevated levels of this cytokine on the day of challenge-exposure. In contrast, immune cats failed to upregulate TNF-mRNA and one manifested strong IFN-mRNA responses.


id: cord-336639-jaue41mv
author: Simons, Fermin A.
title: A mRNA PCR for the diagnosis of feline infectious peritonitis
date: 2004-12-21
extension: .txt
mime: text/plain
words: 3046
sentence: 114
flesch: 48
cache: cache/cord-336639-jaue41mv.txt
txt: txt/cord-336639-jaue41mv.txt
summary:
  Proteins of plasma and ascitic fluid Detection of feline coronaviruses by culture and reverse transcriptase-polymerase chain reaction of blood samples from healthy cats and cats with clinical feline infectious peritonitis Detection of feline coronavirus RNA in feces, tissues, and body fluids of naturally infected cats by reverse transcriptase PCR Elimination of feline coronavirus infection from a large experimental specific pathogen-free catbreeding colony by serologic testing and isolation The prevalence of type I and II feline coronavirus infections in cats Some important disorders of cats The virology and pathogenesis of felineinfectious peritonitis Sequence analysis of the porcine transmissible gastroenteritis coronavirus nucleocapsid protein gene Histopathological alterations of lymphatic tissues in cats without feline infectious peritonitis after long-term exposure to FIP virus The molecular biology of coronaviruses Isolation of Feline Coronaviruses from two cats with divers disease manifestations High viral loads despite absence of clinical and pathological findings in cats experimentally infected with feline coronavirus (FCoV) type I and in naturally FCoV-infected cats Feline infectious peritonitis: Isolation of a coronavirus Feline Infectious Peritonitis (FIP) virus; propagation in suckling rat and hamster brain Virologic and immunologic aspects of feline infectious peritonitis virus infection Infection studies in kittens, using feline infectious peritonitis virus propagated in cell culture An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis Experimental studies with three new strains of feline infectious peritonitis virus: FIPV-UCD2, FIPV-UCD3, and FIPV-UCD4. Although the percentage of PCR-positive healthy animals is much lower when compared to FIP cats, a positive PCR result alone does not allow a definite diagnosis Gunn-Moore et al., 1998 ).


id: cord-281179-k7630is6
author: Brown, Meredith A.
title: Genetic determinants of pathogenesis by feline infectious peritonitis virus
date: 2011-10-15
extension: .txt
mime: text/plain
words: 3214
sentence: 96
flesch: 31
cache: cache/cord-281179-k7630is6.txt
txt: txt/cord-281179-k7630is6.txt
summary:
  Viral gene signatures in the spike Rottier et al., 2005) , NSP 3c (Chang et al., 2010; Pedersen, 2009a) , and membrane (Brown et al., 2009 ) of the coronavirus genome have been shown to often correlate with disease manifestation. Coronaviruses may encode different numbers of NSPs, and the predicted sequences of these proteins do not share high level of homology (Rottier et al., 2005) .


id: cord-336332-9d1h68mi
author: Paltrinieri, Saverio
date: 2003
extension: .txt
mime: text/plain
words: 3699
sentence: 138
flesch: 42
cache: cache/cord-336332-9d1h68mi.txt
txt: txt/cord-336332-9d1h68mi.txt
title:
  Expression patterns in feline blood and tissues of α(1)-acid glycoprotein (AGP) and of an AGP-related protein (AGPrP)

summary:
  During the fAGP purification a second, different protein was identified. Protein concentration was quantified using the BioRadTM Protein Assay (Bio-Rad, Hercules, CA, USA).


id: cord-258374-qht98q0l
author: Takano, Tomomi
date: 2009-04-03
extension: .txt
mime: text/plain
words: 3701
sentence: 148
flesch: 39
cache: cache/cord-258374-qht98q0l.txt
txt: txt/cord-258374-qht98q0l.txt
title:
  Neutrophil survival factors (TNF-alpha, GM-CSF, and G-CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions

summary:
  Risk of feline infectious peritonitis in cats naturally infected with feline coronavirus Gamma interferon/interleukin 10 balance in tissue lymphocytes correlates with down modulation of mucosal feline immunodeficiency virus infection Immune and idiopathic neutropenia Replication of feline coronaviruses in peripheral blood monocytes Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation Polymorphonuclear leukocytemediated cell and tissue injury: oxygen metabolites and their relations to human disease Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes A study on the mechanism of antibody-dependent enhancement of feline infectious peritonitis virus infection in feline macrophages by monoclonal antibodies Enhancement and neutralization of feline infectious peritonitis virus infection in feline macrophages by neutralizing monoclonal antibodies recognizing different epitopes The role of IgG subclass of mouse monoclonal antibodies in antibody-dependent enhancement of feline infectious peritonitis virus infection of feline macrophages Morphologic features and development of granulomatous vasculitis in feline infectious peritonitis Spontaneous neutrophil apoptosis and regulation of cell survival by granulocyte macrophage-colony stimulating factor Asymptomatic bacteriuria in puppies with canine parvovirus infection: a cohort study Neutropenia, neutrophil dysfunction, and bacterial infection in patients with human immunodeficiency virus disease: the role of granulocyte colony-stimulating factor Epstein-Barr virus infects and induces apoptosis in human neutrophils Marrow accessory cell infection and alterations in hematopoiesis accompany severe neutropenia during experimental acute infection with feline immunodeficiency virus Virus infection of endothelial cells increases granulocyte adherence Molecular cloning and sequence determination of the peplomer protein gene of feline infectious peritonitis virus type I Comparison of the amino acid sequence and phylogenetic analysis of the peplomer, integral membrane and nucleocapsid proteins of feline, canine and porcine coronaviruses In vitro effect of recombinant human granulocyte colonystimulating factor on canine neutrophil apoptosis In vitro effect of recombinant human tumor necrosis factor-alpha on canine neutrophil apoptosis A review of feline infectious peritonitis virus: molecular biology, immunopathogenesis, clinical aspects, and vaccination The acute phase reaction Some aspects of humoral and cellular immunity in naturally occurring feline infectious peritonitis Pathogenesis of feline panleukopenia virus and canine parvovirus Programmed cell death of the normal human neutrophil: an in vitro model of senescence Feline infectious peritonitis and feline enteric coronavirus infections. In addition, the presence or absence of neutrophil survival factors was investigated in specimens collected from cats with FIP.


id: cord-295491-zlah6u5s
author: Günther, Sonja
date: 2018-03-11
extension: .txt
mime: text/plain
words: 3796
sentence: 137
flesch: 45
cache: cache/cord-295491-zlah6u5s.txt
txt: txt/cord-295491-zlah6u5s.txt
title:
  Detection of feline Coronavirus in effusions of cats with and without feline infectious peritonitis using loop-mediated isothermal amplification

summary:
  RNA was extracted from body cavity effusion samples of 71 cats, including 34 samples from cats with a definitive diagnosis of FIP, and 37 samples of control cats with similar clinical signs but other confirmed diseases. Body cavity effusion samples of all cats were obtained ante mortem with ultrasound guidance for diagnostic purposes.


id: cord-306829-88nihy7q
author: Sharif, Saeed
title: Diagnostic Methods for Feline Coronavirus: A Review
date: 2010-07-28
extension: .txt
mime: text/plain
words: 3832
sentence: 170
flesch: 44
cache: cache/cord-306829-88nihy7q.txt
txt: txt/cord-306829-88nihy7q.txt
summary:
  Evolutionary insights into the ecology of coronaviruses Coronaviridae An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis Two related strains of feline infectious peritonitis virus coronavirus Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes A review of feline infectious peritonitis virus infection Genetics and pathogenesis of feline infectious peritonitis virus Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis Detection of feline coronavirus RNA in feces, tissues, and body fluids of naturally infected cats by reverse transcriptase PCR Detection of feline coronavirus using RT-PCR: basis for the study of the pathogenesis of feline infectious peritonitis (FIP) Detection of feline coronaviruses by culture and reverse transcriptase-polymerase chain reaction of blood samples from healthy cats and cats with clinical feline infectious peritonitis Intrinsic resistance of feline peritoneal macrophages to coronavirus infection correlates with in vivo virulence An overview of feline enteric coronavirus and infectious peritonitis virus infections Feline infectious peritonitis A comparison of the genomes of FECVs and FIPVs and what they tell us about the relationships between feline coronaviruses and their evolution Molecular cloning and sequence determination of the peplomer protein gene of feline infectious peritonitis virus type I Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis A study of naturally occurring feline coronavirus infections in kittens Persistence and evolution of feline coronavirus in a closed cat-breeding colony Clustering of feline coronaviruses in multicat households Common virus infections in cats, before and after being placed in shelters, with emphasis on feline enteric coronavirus Serological survey of catteries for cats infected with feline coronavirus Prevalence of antibodies against feline coronavirus and Chlamydophila felis in Swedish cats Prevalence of feline coronavirus in two cat populations in Malaysia Pathogenesis of feline enteric coronavirus infection Feline coronavirus infection Review of companion animal viral diseases and immunoprophylaxis Feline infectious peritonitis Incetious diseases Small Animal Radiology and Ultrasonography; A Diagnostic Atlas and Text Laboratory changes consistent with feline infectious peritonitis in cats from multicat environments Infectious Diseases of the Dog and Cat Protein electrophoresis on effusions from cats as a diagnostic test for feline infectious peritonitis Feline infectious peritonitis: a review of clinicopathological changes in 65 cases, and a critical assessment of their diagnostic value An appraisal of the value of laboratory tests in the diagnosis of feline infectious peritonitis Comparison of different tests to diagnose feline infectious peritonitis Feline coronavirus infections, in Infectious Diseases of the Dog and Cat Value of α1-acid glycoprotein in the diagnosis of feline infectious peritonitis Critical assessment of the diagnostic value of feline alpha1-acid glycoprotein for feline infectious peritonitis using the likelihood ratios approach Association between faecal shedding of feline coronavirus and serum α1-acid glycoprotein sialylation Evaluation of an in-practice test for feline coronavirus antibodies Evaluation of antibodies against feline coronavirus 7b protein for diagnosis of feline infectious peritonitis in cats Virion polypeptide specificity of immune complexes and antibodies in cats inoculated with feline infectious peritonitis virus Feline coronavirus type II trains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus SYBR Green real-time reverse transcription-polymerase chain reaction assay for the generic detection of coronaviruses Evaluation of real-time RT-PCR for the quantification of FCoV shedding in the faeces of domestic cats One-tube fluorogenic reverse transcription-polymerase chain reaction for the quantitation of feline coronaviruses Preliminary studies on feline coronavirus distribution in naturally and experimentally infected cats Detection of feline coronavirus RNA in feces, tissues, and body fluids of naturally infected cats by reverse transcriptase PCR Detection of feline coronavirus (FCoV) using reverse transcriptase polymerase chain reaction (RT-PCR) Genetic diversity and phylogenetic analysis of Feline Coronavirus sequences from Portugal One-step SYBR green-based real-time reverse transcriptase polymerase chain reaction assay for detection of feline coronavirus Persistence and transmission of natural type I feline coronavirus infection Phylogenetic analysis of feline coronavirus isolates from healthy cats in Malaysia Descriptive distribution and phylogenetic analysis of feline infectious peritonitis virus isolates of Malaysia A mRNA PCR for the diagnosis of feline infectious peritonitis Feline infectious peritonitis: typical findings and a new PCR test The detection of feline coronaviruses in blood samples from cats by mRNA RT-PCR Development of a nested PCR assay for detection of feline infectious peritonitis virus in clinical specimens Detection of feline coronaviruses in cell cultures and in fresh and fixed feline tissues using polymerase chain reaction Feline infectious peritonitis The authors wish to thank Dr. Diane Addie (www.catvirus.com) for providing the photograph and proofreading the paper. Two biological types of FCoVs are known: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV).


id: cord-336730-hqgwj8vs
author: Fehr, Daniela
date: 1997-07-31
extension: .txt
mime: text/plain
words: 4309
sentence: 173
flesch: 52
cache: cache/cord-336730-hqgwj8vs.txt
txt: txt/cord-336730-hqgwj8vs.txt
title:
  Placebo-controlled evaluation of a modified life virus vaccine against feline infectious peritonitis: safety and efficacy under field conditions

summary:
  However, if the incidence of FIP cases during the first 150 days after vaccination were compared in vaccinated vs placebo cats, there is absolutely no difference in that 12 cats in the vaccine group and 11 cats in the placebo group died during this time. Under experimental conditions, vaccination of FCoV naive cats was also found to reduce the incidence and the severity of infections with the low virulent viruses called FECV38.


id: cord-304616-k92fa15l
author: Izes, Aaron M.
date: 2020-08-05
extension: .txt
mime: text/plain
words: 4213
sentence: 171
flesch: 44
cache: cache/cord-304616-k92fa15l.txt
txt: txt/cord-304616-k92fa15l.txt
title:
  Assay validation and determination of in vitro binding of mefloquine to plasma proteins from clinically normal and FIP-affected cats

summary:
  A simple, high pressure liquid chromatography assay was developed to detect mefloquine plasma concentrations in feline plasma. In vitro hepatic metabolism of mefloquine using microsomes from cats, dogs and the common brush-tailed possum (Trichosurus vulpecula) Predicting plasma protein binding of drugs: a new approach Drug-protein binding: a critical review of analytical tools Clinical pharmacokinetics of mefloquine Positive predictive value of albumin: globulin ratio for feline infectious peritonitis in a mid-western referral hospital population A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans Defining limit of detection and limit of quantitation as applied to drug of abuse testing: striving for a consensus International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Prevalence of feline immunodeficiency virus infection in domesticated and feral cats in eastern Australia Risk factors for feline infectious peritonitis in Australian cats pH adjustment of human blood plasma prior to bioanalytical sample preparation Chemistry (cobas) reference intervals In vitro hepatic metabolism of mefloquine using microsomes from cats, dogs and the common brush-tailed possum Clinical application of mefloquine pharmacokinetics in the treatment of P. falciparum malaria In vitro binding of cefovecin to plasma proteins in Australian marsupials and plasma concentrations of cefovecin following single subcutaneous administration to koalas (Phascolarctos cinereus) Species differences in drug plasma protein binding Selective plasma protein binding of antimalarial drugs to α1-acid glycoprotein Plasma protein binding and blood-free concentrations: which studies are needed to develop a drug? Serum protein concentrations in Plasmodium falciparum malaria Critical assessment of the diagnostic value of feline α1-acid glycoprotein for feline infectious peritonitis using the likelihood ratios approach Protein binding of antimicrobials: methods for quantification and for investigation of its impact on bacterial killing Errors in estimating the unbound fraction of drugs due to the volume shift in equilibrium dialysis Clinical pharmacology: plasma protein binding of drugs What is the true clinical significance of plasma protein binding displacement interactions?


id: cord-253498-w6qfzpi4
author: Paltrinieri, Saverio
date: 2010-08-02
extension: .txt
mime: text/plain
words: 4301
sentence: 165
flesch: 41
cache: cache/cord-253498-w6qfzpi4.txt
txt: txt/cord-253498-w6qfzpi4.txt
title:
  Electrophoretic fractionation of creatine kinase isoenzymes and macroenzymes in clinically healthy dogs and cats and preliminary evaluation in central neurologic disease

summary:
  1 CK is primarily cytoplasmic and leakage from injured or inflamed tissues leads to increased CK activity in blood, permitting assay of plasma or serum CK activity as a biomarker of tissue damage. Total CK activity was greater in cats with FIP than in healthy cats, but this finding has poor diagnostic specificity as increased CK activity occurs in several pathophysiologic conditions, including anorexia, 17 myopathy, 18 metabolic syndromes, 25 and CNS disorders.


id: cord-270414-gh9agf4x
author: Fischer, Y.
date: 2011-10-12
extension: .txt
mime: text/plain
words: 4583
sentence: 222
flesch: 50
cache: cache/cord-270414-gh9agf4x.txt
txt: txt/cord-270414-gh9agf4x.txt
title:
  Randomized, Placebo Controlled Study of the Effect of Propentofylline on Survival Time and Quality of Life of Cats with Feline Infectious Peritonitis

summary:
  Cats also received low molecular weight heparin (dalteparid sodium) to minimize the risk of a disseminated intravascular coagulation (DIC), which is often observed in cats with FIP. key: cord-270414-gh9agf4x authors: Fischer, Y.; Ritz, S.; Weber, K.; Sauter‐Louis, C.; Hartmann, K. title: Randomized, Placebo Controlled Study of the Effect of Propentofylline on Survival Time and Quality of Life of Cats with Feline Infectious Peritonitis date: 2011-10-12 journal: J Vet Intern Med DOI: 10.1111/j.1939-1676.2011.00806.x sha: doc_id:


id: cord-327352-cbnjsrmt
author: Kipar, A
date: 1998-10-23
extension: .txt
mime: text/plain
words: 4926
sentence: 204
flesch: 32
cache: cache/cord-327352-cbnjsrmt.txt
txt: txt/cord-327352-cbnjsrmt.txt
title:
  Cellular composition, coronavirus antigen expression and production of specific antibodies in lesions in feline infectious peritonitis

summary:
  A variably large area of central necrosis was surrounded by inflammatory cells which were almost completely identified as macrophages (Figs. 1(b) and 4(b) ). Based on immunohistological and histochemical characterization of inflammatory cells as well as the presence of coronavirus antigen and plasma-cells producing coronavirus-specific antibodies in the lesions of 23 cats with spontaneous FIP, this study describes the composition of alterations observed in FIP after natural infection.


id: cord-308537-i6um5iu2
author: Hoskins, Johnny D.
title: Coronavirus Infection in Cats
date: 1993-01-31
extension: .txt
mime: text/plain
words: 5270
sentence: 241
flesch: 35
cache: cache/cord-308537-i6um5iu2.txt
txt: txt/cord-308537-i6um5iu2.txt
summary:
  28 Most cats subsequently do not show clinical evidence of FIP coronavirus infection. Removal of healthy coronavirus antibodypositive cats from catteries or multicat household is justified only if strong evidence that the cat is a source of FIP coronavirus infection for other cats exists.


id: cord-315094-pzixgqcy
author: Benetka, Viviane
date: 2004-03-26
extension: .txt
mime: text/plain
words: 5539
sentence: 176
flesch: 48
cache: cache/cord-315094-pzixgqcy.txt
txt: txt/cord-315094-pzixgqcy.txt
title:
  Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis

summary:
  CCV exhibits an identity to FCoV-1 KU-2 of 72%; its much closer relationship to FCoV type II than to FCoV type I can nicely be observed by the similarity of several nucleotide changes of FCoV type II and CCV. These findings demonstrate that in FIP cases FCoV type I predominates, too, nonetheless, in 14% of the cases FCoV type II was detected, suggesting its causative involvement in cases of FIP.


id: cord-319685-dw0qsl4s
author: Porter, Emily
date: 2014-04-25
extension: .txt
mime: text/plain
words: 5692
sentence: 208
flesch: 52
cache: cache/cord-319685-dw0qsl4s.txt
txt: txt/cord-319685-dw0qsl4s.txt
title:
  Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis

summary:
  Overall, a leucine codon was found in the majority (39/43; 91%) of FIP tissue samples, but a significant number had a methionine codon (4/43; 9%). Second, a significant number (9%) of FIP tissue samples had a methionine codon at this position.


id: cord-348746-yaf61cmx
author: Foley, Janet E.
title: A Review of Coronavirus Infection in the Central Nervous System of Cats and Mice
date: 2008-06-28
extension: .txt
mime: text/plain
words: 5481
sentence: 227
flesch: 30
cache: cache/cord-348746-yaf61cmx.txt
txt: txt/cord-348746-yaf61cmx.txt
summary:
  Isolation and characterization of feline C3 and evidence for the immune complex pathogenesis of feline infectious peritonitis Pathogenesis of feline infectious peritonitis: Nature and development of viremia Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization A study on the mechanism of antibody-dependent enhancement of feline infectious peritonitis virus infection in feline macrophages by monoclonal antibodies Monoclonal antibodies to the spike protein of feline infectious peritonitis virus mediate antibody-dependent enhancement of infection of feline macrophages Monoclonal antibody analysis of neutralization and antibody-dependent enhancement of feline infectious peritonitis virus Cytokine expression in feline lymphoid tissue in health and disease Antibody and cytokine responses in kittens during the development of feline infectious peritonitis (FIP) Interleukin 1 alpha mRNA-expressing cells on the local inflammatory response in feline infectious peritonitis Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells In vivo effects of coronavirus-specific T cell clones: DTH inducer cells prevent a lethal infection but do not inhibit virus replication Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis Demyelination induced by murine hepatitis virus JHM strain (MHV-4) is immunologically mediated Population dynamics of lymphocyte subsets in the central nervous system of rats with different susceptibility to coronavirus-induced demyelinating encephalitis Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells Infection with cytotoxic T-lymphocyte escape mutants results in increased mortality and growth retardation in mice infected with a neurotropic coronavirus Apoptosis induced in mouse hepatitis virus-infected cells by a virus-specific CD8ϩ cytotoxic Tlymphocyte clone Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. The causative agent, FIP virus (FIPV), is a macrophage-tropic mutant of the ubiquitous feline enteric coronavirus (FECV).


id: cord-323805-9n63ms3c
author: Pedersen, Niels C.
date: 2014-11-15
extension: .txt
mime: text/plain
words: 5751
sentence: 213
flesch: 43
cache: cache/cord-323805-9n63ms3c.txt
txt: txt/cord-323805-9n63ms3c.txt
title:
  The influence of age and genetics on natural resistance to experimentally induced feline infectious peritonitis

summary:
  Cats from family A were sired by multiple related cats while cats in families B and C were each descended from a single sire. Foley et al. (1997) studied a number of environmental risk factors for FIP in seven catteries and found that cat numbers (density) and husbandry procedures had no influence on FIP incidence while age, high coronavirus antibody titers, and the proportion of cats shedding coronavirus were significantly associated with FIP risk.


id: cord-268492-0rbmqarx
author: Alberer, Martin
date: 2020-09-02
extension: .txt
mime: text/plain
words: 1534
sentence: 56
flesch: 36
cache: cache/cord-268492-0rbmqarx.txt
txt: txt/cord-268492-0rbmqarx.txt
title:
  Cats and kids: how a feline disease may help us unravel COVID-19 associated paediatric hyperinflammatory syndrome

summary:
  Similarities to children presenting with Kawasaki disease (KD) have been reported in some of these critically ill children while some of them predominantly display features of toxic shock, such as seen in severe staphylococcal or streptococcal infection. In human COVID-19, these cytokines have been associated with a severe course of disease and deemed to be the hallmark cytokines of the cytokine storm.


id: cord-271078-zyy8gx25
author: Sharif, Saeed
date: 2010-01-06
extension: .txt
mime: text/plain
words: 2121
sentence: 100
flesch: 48
cache: cache/cord-271078-zyy8gx25.txt
txt: txt/cord-271078-zyy8gx25.txt
title:
  Descriptive distribution and phylogenetic analysis of feline infectious peritonitis virus isolates of Malaysia

summary:
  Kajian Vet Malaysia Retrospective examination of feline infectious peritonitis cases presented to University Veterinary Hospital, Universiti Putra Malaysia (UVH-UPM) between Serological survey of catteries for cats infected with feline coronavirus Prevalence of feline coronavirus in two cat populations in Malaysia Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis Genetic diversity and phylogenetic analysis of feline coronavirus sequences from Portugal Feline infectious peritonitis in a closed breeding colony Prevalence of feline infectious peritonitis in specific cat breeds Phylogenetic analysis of feline coronavirus isolates from healthy cats in Malaysia Quasispecies composition and phylogenetic analysis of feline coronaviruses (FCoVs) in naturally infected cats Genomic RNA sequence of feline coronavirus strain FIPV WSU-79/1146 The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes Genomic organization and expression of the 3' end of the canine and feline enteric coronaviruses Descriptive distribution and phylogenetic analysis of feline infectious peritonitis virus isolates of Malaysia However, the result is consistent with other studies demonstrating higher incidence of FIP in cats below 2 years of age [5, 11, 14] and agree with the fact that FIP is a disease of young cats.


id: cord-351955-9l4786lb
author: Pedersen, Niels C.
date: 2009-08-26
extension: .txt
mime: text/plain
words: 6791
sentence: 277
flesch: 54
cache: cache/cord-351955-9l4786lb.txt
txt: txt/cord-351955-9l4786lb.txt
title:
  Significance of Coronavirus Mutants in Feces and Diseased Tissues of Cats Suffering from Feline Infectious Peritonitis

summary:
  There is also evidence that FIPV may have been shed in urine of FIPV infected cats [35] , and that coronavirus may be present in the blood, especially among younger cats [36] . As with the earlier study [17] , all or almost all of the fecal isolates from diseased cats and a healthy contact control animal had intact 3c genes.


id: cord-322317-wsagoy52
author: Stranieri, Angelica
date: 2020-10-18
extension: .txt
mime: text/plain
words: 7553
sentence: 267
flesch: 42
cache: cache/cord-322317-wsagoy52.txt
txt: txt/cord-322317-wsagoy52.txt
title:
  Concordance between Histology, Immunohistochemistry, and RT-PCR in the Diagnosis of Feline Infectious Peritonitis

summary:
  Histological examination was performed on 93 tissue samples obtained from FIP cats and 83 obtained from non FIP cats. On the other hand, non FIP cats are less likely to shed the virus in the feces compared with FIP cats [17] .


id: cord-283202-5fq1wxz8
author: Kent, Marc
title: The cat with neurological manifestations of systemic disease. Key conditions impacting on the CNS
date: 2009-05-31
extension: .txt
mime: text/plain
words: 7334
sentence: 385
flesch: 36
cache: cache/cord-283202-5fq1wxz8.txt
txt: txt/cord-283202-5fq1wxz8.txt
summary:
  Unfortunately, very few references provide detailed descriptions of large cohorts of affected cats. 18 Hematology in affected cats usually reveals a normocytic, normochromic, nonregenerative anemia, leukocytosis consisting of a neutrophilia, and lymphopenia.


id: cord-264315-3hum7rqm
author: Paltrinieri, S
date: 2001-09-30
extension: .txt
mime: text/plain
words: 3786
sentence: 123
flesch: 31
cache: cache/cord-264315-3hum7rqm.txt
txt: txt/cord-264315-3hum7rqm.txt
title:
  Laboratory profiles in cats with different pathological and immunohistochemical findings due to feline infectious peritonitis (FIP)

summary:
  Feline infectious peritonitis: a review of clinicopathological changes in 65 cases, and a critical assessment of their diagnostic value The dendritic cell system and its role in immunogenicity Cats inoculated with feline infectious peritonitis virus exhibit a biphasic acute phase plasma protein response Immunological demonstration of feline infectious peritonitis virus antigen in paraffin-embedded tissues using feline ascites or murine monoclonal antibodies A comparison of the genomes of FECVs and FIPVs: what they tell us about relationship between feline coronaviruses and their evolution Eine modification der ABC-methode (avidin-biotin-peroxidase-complex) fü r den nachweis von viralen antigenen bei der infektion der katze durch ein coronavirus (FIP) und der infektion des hundes durch das parvovirus-typ 2 Feline infectious peritonitis: experimental evidence for its multiphasic nature Pathogenesis of feline infectious peritonitis: pathologic changes and immunofluorescence The risk of feline infectious peritonitis in cats naturally infected with feline coronavirus Feline Infectious Peritonitis Using direct immunofluorescence to detect coronaviruses in peritoneal and pleural effusion Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections The inheritance of susceptibility to feline infectious peritonitis in purebreed cats Antibody and cytokine responses in kittens during the development of feline infectious peritonitis (FIP) Apoptosis and T-cell depletion during feline infectious peritonitis Systemic vascular lesions in feline infectious peritonitis Detection of feline coronavirus RNA in feces, tissue and body fluids of naturally infected cats by reverse transcriptase PCR Persistence and evolution of feline coronavirus in a closed cat-breeding colony Enhancement and neutralization of feline inectious peritonitis infection in feline macrophages by neutralizing monoclonal antibodies recognizing different epitopes The role of IgG subclass of mouse monoclonal antibodies in antibodydependent enhancement of feline infectious peritonitis virus infection of feline macrophages Use of avidin-biotinperoxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures Antibody, immune complexes, and complement activity fluctuations in kittens with experimentally induced feline infectious peritonitis Essential of veterinary hematology Blood analyte reference values in small and some laboratory animals Antibody production in situ in cats with feline infectious peritonitis Cellular composition, coronavirus antigen expression and production of specific antibodies in lesions in feline infectious peritonitis Histopathological alterations of lymphatic tissues in cats without feline infectious peritonitis after long term exposure to FIP virus Analysis of serum proteins in clinically normal pet and colony cats, using agarose electrophoresis Type IV hypersensitivity in the pathogenesis of FIPV induced lesions Some aspects of humoral and cellular immunity in spontaneously occuring feline infectious peritonitis Tecniche ematologiche Serologic studies of naturally occurring feline infectious peritonitis Virologic and immunologic aspects of feline infectious peritonitis virus infection An overview of feline enteric coronavirus and infectious peritonitis virus infections The history and interpretation of feline coronavirus serology Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus Problems in the interpretation of feline coronavirus serology (specificity vs. sensitivity of test procedures)


id: cord-023121-hewbl5yu
author: Parodi, M. Cammarata
date: 2008-04-10
extension: .txt
mime: text/plain
words: 2390
sentence: 87
flesch: 36
cache: cache/cord-023121-hewbl5yu.txt
txt: txt/cord-023121-hewbl5yu.txt
title:
  Using direct immunofluorescence to detect coronaviruses in peritoneal in peritoneal and pleural effusions

summary:
  Cats, coronaviruses and coronavirus antibody tests Feline infectious peritonitis Encephalitis due to feline infectious peritonitis virus in a twelve-week-old kitten Viral diseases: feline infectious peritonitis Ocular manifestation of feline infectious peritonitis Ricerca degli anticorpi anti-FIPV in gatti sani e malati mediante tecnica immuno-enzimatica competitiva (C-ELISA) Coronaviridae. key: cord-023121-hewbl5yu authors: Parodi, M. Cammarata; Cammarata, G.; Paltrinieri, S.; Lavazza, A.; Ape, F. title: Using direct immunofluorescence to detect coronaviruses in peritoneal in peritoneal and pleural effusions date: 2008-04-10 journal: J Small Anim Pract DOI: 10.1111/j.1748-5827.1993.tb02591.x sha: doc_id: 23121 cord_uid: hewbl5yu Twenty‐one cases of feline infectious peritonitis (FIP) were diagnosed using a direct immunofluorescence test on cytocentrifuged pleural and peritoneal effusions from cats sampled in vivo (11 cases) and at necropsy (10 cases).


id: cord-285335-agm4zbcx
author: Kennedy, Melissa
date: 2001-08-08
extension: .txt
mime: text/plain
words: 2294
sentence: 103
flesch: 52
cache: cache/cord-285335-agm4zbcx.txt
txt: txt/cord-285335-agm4zbcx.txt
title:
  Deletions in the 7a ORF of feline coronavirus associated with an epidemic of feline infectious peritonitis

summary:
  The inheritance of susceptibility to feline infectious peritonitis in purebred catteries The molecular genetics of feline coronavirus: comparative sequence analysis of the ORF 7a/7b transcription unit of different biotypes Perspectives on feline coronavirus evolution Veterinary Clinics of North America: Small Animal Practice Correlation of genomic detection of feline coronavirus with various diagnostic assays for feline infectious peritonitis Genetic basis for species vulnerability in the cheetah Virologic and immunologic aspects of feline infectious peritonitis virus infection An overview of feline enteric coronavirus and infectious peritonitis virus infections Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus Evaluation of the safety and efficacy of Primucell-FIP vaccine Genomic organization and expression of the 3 0 -end of the canine and feline enteric coronaviruses Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses (1998) that FIP viruses contained tyrosine and lysine at these positions whereas putative avirulent FCoV contained histidine and arginine.


id: cord-022203-t2f0vr1w
author: Dowers, Kristy L
title: The pyrexic cat
date: 2009-05-15
extension: .txt
mime: text/plain
words: 8911
sentence: 674
flesch: 50
cache: cache/cord-022203-t2f0vr1w.txt
txt: txt/cord-022203-t2f0vr1w.txt
summary:
  However, some cats do not develop detectable IgM titers, and in other cats, positive IgM titers can persist for months to years after infection. The condition, however, does not appear to be contagious to other cats.


id: cord-302161-ytr7ds8i
author: Lutz, Mirjam
date: 2020-07-24
extension: .txt
mime: text/plain
words: 9917
sentence: 365
flesch: 50
cache: cache/cord-302161-ytr7ds8i.txt
txt: txt/cord-302161-ytr7ds8i.txt
title:
  FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP

summary:
  To track viral sequence mutations in organs of healthy FCoV carrier cats, we investigated FCoV sequences detected in the colon, liver, and thymus, as well as feces of seven experimentally FCoV infected cats. The overall comparison of FCoV gene sequences from the different cats euthanized at different time points after infection did not reveal any significant differences (Table 3) .


id: cord-273424-iz1vat9p
author: Ceciliani, Fabrizio
date: 2004-04-12
extension: .txt
mime: text/plain
words: 3736
sentence: 159
flesch: 46
cache: cache/cord-273424-iz1vat9p.txt
txt: txt/cord-273424-iz1vat9p.txt
title:
  Decreased sialylation of the acute phase protein α1-acid glycoprotein in feline infectious peritonitis (FIP)

summary:
  Using the lectin MAA, the sialic acid a(2-3)-linked content of pathological fAGP decreases to an average value of 44% when compared to non-pathological fAGP. Fig. 3 reports the glycosylation patterns of fAGP purified from FIP affected cats: lane np represents pooled non-patological fAGP, while pathological fAGP from the 24 FIP affected cats were loaded onto lanes 1-24.


id: cord-317411-6lc0wpoo
author: Giori, L.
date: 2011-02-21
extension: .txt
mime: text/plain
words: 3541
sentence: 105
flesch: 30
cache: cache/cord-317411-6lc0wpoo.txt
txt: txt/cord-317411-6lc0wpoo.txt
title:
  Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases

summary:
  Five cats with FIP had in vivo tests partially consistent with FIP, including the presence of effusions, but postmortem examination findings were atypical due to the presence of the following: mesenteric fibrotising lymphadenopathy without additional lesions (cats 5 and 12), intestinal pyogranulomatous lesions containing Ziehl-Neelsen positive rods and Periodic acid-schiff (PAS)-positive fungal hyphae (cat 8), segmental thickening of the intestinal wall histologically characterised by severe fibrosis (cat 10, Fig 2) Intralesional FCoVs were detected by IHC in all the eight cats belonging to this group (Fig 4) . Final diagnosis in the four cats without FIP These four cats had symptoms consistent with FIP such as uveitis (cat 1) or effusions (cats 2, 3 and 4), but FIP was excluded for the summarise, in cats without FIP, the clinical features and intracavitary effusions, when present, were always consistent with FIP.


id: cord-276617-chgjpg0v
author: Takano, Tomomi
date: 2008-11-30
extension: .txt
mime: text/plain
words: 3982
sentence: 163
flesch: 44
cache: cache/cord-276617-chgjpg0v.txt
txt: txt/cord-276617-chgjpg0v.txt
title:
  B-cell activation in cats with feline infectious peritonitis (FIP) by FIP-virus-induced B-cell differentiation/survival factors

summary:
  Moreover, increased levels of interleukin (IL)-6, a cytokine involved in the survival of B-cells and their differentiation into plasma cells, in ascites T. Takano Á N. Azuma Á Y. Hashida Á R. Satoh Á T. Hohdatsu (&) Laboratory of Veterinary Infectious Disease, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan e-mail: hohdatsu@vmas.kitasato-u.ac.jp and culture supernatant of peritoneal exudative cells (PEC) from FIP cats have been reported [8] . Thus, the number of plasma cells may increase in the peripheral blood of FIP cats.


id: cord-254375-otj044by
author: Paltrinieri, S
title: Some aspects of humoral and cellular immunity in naturally occuring feline infectious peritonitis
date: 1998-10-23
extension: .txt
mime: text/plain
words: 5154
sentence: 184
flesch: 36
cache: cache/cord-254375-otj044by.txt
txt: txt/cord-254375-otj044by.txt
summary:
  All globulin fractions increased in FIP cats, but the increase was lower in -(P<0.05) than in -(P<0.01) and in g-(P>0.001) globulins; the increase of -globulins was due mainly to an increase in the 2 fraction (P<0.05). The electrophoretic pattern of FIP cats was consistent with those reported in literature (Sparkes et al., 1991 (Sparkes et al., , 1994 Pedersen, 1995a) .


id: cord-266155-hf3retap
author: Addie, Diane D.
title: Oral Mutian®X stopped faecal feline coronavirus shedding by naturally infected cats
date: 2020-06-30
extension: .txt
mime: text/plain
words: 6020
sentence: 198
flesch: 52
cache: cache/cord-266155-hf3retap.txt
txt: txt/cord-266155-hf3retap.txt
summary:
  Little is known about FCoV-II shedding, in one experimental infection of laboratory cats virus was shed for up to 15 days (Stoddart et al., 1988) ; and no persistently FCoV-II infected cat has been reported (Addie and Jarrett, 2001; Addie et al., 2003) . Also, if the serum anti-FCoV titres of treated cats decline over the coming year, it will indicate that the virus has been cleared systemically, as well as from the gastrointestinal tract.


id: cord-313439-cadyykks
author: Felten, Sandra
title: Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature
date: 2019-11-15
extension: .txt
mime: text/plain
words: 12473
sentence: 455
flesch: 40
cache: cache/cord-313439-cadyykks.txt
txt: txt/cord-313439-cadyykks.txt
summary:
  Pathogenesis of feline enteric coronavirus infection Common virus infections in cats, before and after being placed in shelters, with emphasis on feline enteric coronavirus Pathogenic characteristics of persistent feline enteric coronavirus infection in cats Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses Infection studies in kittens, using feline infectious peritonitis virus propagated in cell culture An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis Clinical and laboratory features of cats with feline infectious peritonitis-a retrospective study of 231 confirmed cases (2000-2010) Prevalence of feline infectious peritonitis in specific cat breeds Epidemiology of feline infectious peritonitis among cats examined at veterinary medical teaching hospitals The inheritance of susceptibility to feline infectious peritonitis in purebred catteries Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases A review of feline infectious peritonitis virus infection: 1963-2008 Feline infectious peritonitis: Still an enigma? Immunologic phenomena in the effusive form of feline infectious peritonitis Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures Cats inoculated with feline infectious peritonitis virus exhibit a biphasic acute phase plasma protein response Serologic studies of naturally occurring feline infectious peritonitis Feline coronavirus antibodies in cats Utility of feline coronavirus antibody tests Seroepidemiology of feline infectious peritonitis virus infections using transmissible gastroenteritis virus as antigen Feline infectious peritonitis: A worldwide serosurvey Feline coronavirus serotypes 1 and 2: Seroprevalence and association with disease in switzerland Evaluation of an in-practice test for feline coronavirus antibodies Comparison of serologic techniques for the detection of antibodies against feline coronaviruses The history and interpretation of feline coronavirus serology A. Cats and coronaviruses Long-term impact on a closed household of pet cats of natural infection with feline coronavirus, feline leukaemia virus and feline immunodeficiency virus A study of naturally occurring feline coronavirus infections in kittens Risk of feline infectious peritonitis in cats naturally infected with feline coronavirus Coronavirus serology in healthy pedigree cats


id: cord-284963-p0y5rrpb
author: Kipar, Anja
date: 2006-08-15
extension: .txt
mime: text/plain
words: 6443
sentence: 210
flesch: 38
cache: cache/cord-284963-p0y5rrpb.txt
txt: txt/cord-284963-p0y5rrpb.txt
title:
  Natural feline coronavirus infection: Differences in cytokine patterns in association with the outcome of infection

summary:
  Primer (f, r) and probe (p) sequences were as previously published for the following systems: IL-1b (76 bp PCR product; Kipar et al., 2001b) , IL-6 (110 bp PCR product; Kipar et al., 2001a,b) , IL-10 (76 bp PCR product; Leutenegger et al., 1999) , IL-12 p40 (81 bp PCR product; Leutenegger et al., 1999) , TNF (74 bp PCR product; Kipar et al., 2001b) and GAPDH (82 bp PCR product; Leutenegger et al., 1999) . Previous studies revealed major differences in the composition and functional state of lymphatic tissues of FCoV-infected cats with and without FIP (Kipar et al., 1999 (Kipar et al., , 2001a .


id: cord-021452-9rukc80y
author: Bergman, Robert L.
title: Miscellaneous Spinal Cord Diseases
date: 2009-05-15
extension: .txt
mime: text/plain
words: 8317
sentence: 519
flesch: 46
cache: cache/cord-021452-9rukc80y.txt
txt: txt/cord-021452-9rukc80y.txt
summary:
  Dose-response and time-action analysis The neuroprotective pharmacology of methylprednisolone Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na + K + )-ATPase, lipid peroxidation, and alpha motor neuron function Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intravenous dose of methylprednisolone Effects of multi-dose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism Evaluation of an intensive methylprednisolone sodium succinate dosing regimen in experimental spinal cord injury Pretreatment with alpha tocopherol enhances neurologic recovery after experimental spinal cord compression injury Management of spinal trauma in 69 cats Survival rates and outcomes in cats with thoracic and lumbar spinal cord injuries due to external trauma High-rise syndrome in cats: 207 cases Tension band stabilization of fractures and luxations of the thoracolumbar vertebrae in dogs and cats: 38 cases Combined medical and surgical treatment after acute spinal cord injury: results of a prospective pilot study to assess the merits of aggressive medical resuscitation and blood pressure management Methylprednisolone for acute spinal cord injury: an inappropriate standard of care Is the role of steroids in acute spinal cord injury now resolved? High dose methylprednisolone in the management of acute spinal cord injury -a systematic review from a clinical perspective Gastric hemorrhage in dogs given high doses of methylprednisolone sodium succinate Complications of methylprednisolone sodium succinate therapy in dachshunds with surgically treated intervertebral disc disease Evaluation of time-dependent spread of tissue damage in experimental spinal cord injury by killedend evoked potential: effect of high-dose methylprednisolone Nonsurgical management of thoracic and lumbar spinal fractures and fractures/luxations in the dog and cat: a review of 17 cases Management of vertebral column fractures in dogs and cats: 211 cases (1977-1985) Spinal fracture or luxation Reversible spinal cord trauma in cats. Additive effects of direct pressure and ischemia An evidence-based review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies Current use and timing of spinal surgery for management of acute spinal cord injury in North America: results of a retrospective multicenter study Principles of vertebral fracture management Use of pins and methylmethacrylate in stabilization of spinal fractures and luxations The rotational stabilizing effect of spinal fixation techniques in an unstable vertebral model Recovery of locomotion in the cat following spinal cord lesions Determinants of locomotor recovery after spinal injury in the cat Locomotor capacity attributable to step training versus spontaneous recovery after spinalization in adult cats Effects of training on the recovery of full weight bearing stepping in the adult spinal cat Return of weight supported locomotion in adult spinal cats Chronic spinal cord-injured cats: surgical procedures and management Retention of hindlimb stepping ability in adult spinal cats after the cessation of step training Feline intervertebral disc disease: a review of the literature Intervertebral disc extrusion in six cats Intervertebral disk disease in 10 cats Spontaneous lumbar intervertebral disc protrusion in cats: literature review and case presentations Disc protrusions in the cat: distribution of dorsal protrusions along the vertebral column Disc protrusions in the cat: age incidence of dorsal protrusions Disc protrusions in the cat: ventral protrusions and radial splits Degeneration of the intervertebral disc in the cat Protrusion of the intervertebral disc in the cat Intervertebral disc syndrome in the cat Intervertebral disc protrusion in a cat Acute intervertebral disc extrusion in a cat: clinical and MRI findings Lumbosacral disc disease in a cat Radiographic diagnosis: intervertebral disc extrusion in a cat Fibrocartilaginous embolic myelopathy in a cat Tetraparesis in a cat with fibrocartilaginous emboli Fibro-cartilaginous embolism in a cat Syringomyelia and hydromyelia in dogs and cats Subarachnoid cyst in a cat Correlative imaging findings in seven dogs and one cat with spinal arachnoid cysts Spinal subarachnoid cyst in a cat Intradural epithelial cyst in a cat


id: cord-022555-a7ie82fs
title: Digestive System, Liver, and Abdominal Cavity
date: 2011-12-05
extension: .txt
mime: text/plain
words: 66503
sentence: 3320
flesch: 46
cache: cache/cord-022555-a7ie82fs.txt
txt: txt/cord-022555-a7ie82fs.txt
summary:
  The worm is transmitted to other cats that ingest the vomitus of an infected cat. Other cats should not be allowed to ingest infected vomit.


id: cord-014527-nvzfpntu
title: Research Communications of the 25th ECVIM‐CA Congress
date: 2015-11-09
extension: .txt
mime: text/plain
words: 89290
sentence: 4308
flesch: 49
cache: cache/cord-014527-nvzfpntu.txt
txt: txt/cord-014527-nvzfpntu.txt
summary:
  Dogs in the prolonged OS group were more likely to be anaemic on presentation (PCV<37%, P = 0.041), experienced a greater FRD (P = 0.012) and were more likely to be treated with a rescue protocol (P = 0.036) than other dogs. Dogs that did not respond to treatment had significantly higher S100A12 levels than dogs with partial (P = 0.005) or complete (P = 0.003) remission, but response to treatment was associated with disease classification (P = 0.020).


