id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-000252-iejfgkst	Chen, YanYi	Calciomics: prediction and analysis of EF-hand calcium binding proteins by protein engineering	2010-02-07		.txt	text/plain	4230	153	40	First, what are the site-specific calcium binding affinities of calcium binding proteins, particularly those that utilize multiple coupled calcium binding sites to respond to sharp changes in cellular calcium concentration? Further, since most calcium binding proteins contain multiple calcium binding sites that cooperatively bind calcium resulting in induced conformational change (e.g., CaM) ( Figure 2 ), obtaining site-specific calcium binding affinity is limited by complication from contributions from cooperativity and conformational entropy [23] .	cache/cord-000252-iejfgkst.txt	txt/cord-000252-iejfgkst.txt
