item: #1 of 59
          id: cord-000083-3p81yr4n
      author: None
       title: Poster Exhibition
        date: 2009-01-31
       words: 113010
      flesch: 51
     summary: From this group of HBV patients 35 (98%) have had elevated urinal Dol excreation (45,8±5,2 g/ml vs . 3% and 47.4 respectively in HCC patients, 60.3% and 39.7 in LC patients, 55% and 40 in CHB patients, 55% and 40 in ACLF patients.
    keywords: activity; acute; adefovir; adv; afp; age; aim; aims; alt; alt levels; analysis; anti; assay; associated; b virus; background; baseline; blood; cancer; carcinoma; cases; cells; chb patients; china; chronic hcv; chronic hepatitis; clinical; combination; conclusion; control; control group; copies; correlation; data; days; development; diagnosis; difference; dna levels; dose; drug; effect; efficacy; end; etv; expression; factors; fibrosis; follow; gene; genotype; group; group b; hbeag; hbv dna; hbv genotype; hbv infection; hcc cell; hcc patients; hcv; hepatic; hepatitis b; hepatitis patients; hepatocellular; hospital; ifn; increase; infected; lamivudine; levels; liver; liver biopsy; liver cirrhosis; liver disease; load; low; male; markers; mean; median; medical; methods; model; months; mrna; mutation; nafld; negative; non; p<0.05; patients; patients chronic; pcr; positive; prevalence; protein; rate; ratio; rats; recurrence; related; resistance; respectively; response; results; rfa; risk; rna; role; samples; score; seroconversion; serum alt; serum hbv; significant; specific; study; study group; subjects; survival; svr; therapy; time; total; treatment; treatment group; tumor; university; virus; weeks; years
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        item: #2 of 59
          id: cord-003520-f3jz59pt
      author: Arabi, Yaseen M.
       title: Free Fatty Acids’ Level and Nutrition in Critically Ill Patients and Association with Outcomes: A Prospective Sub-Study of PermiT Trial
        date: 2019-02-13
       words: 4292
      flesch: 46
     summary: The aims of this study were (1) to evaluate the clinical and nutritional correlates of high FFAs level in critically ill patients and the association with outcomes, and (2) study the effect of short-term caloric restriction (permissive underfeeding) on FFAs level during critical illness. Of 70 enrolled patients, 23 (32.8%) patients had high FFAs level (baseline FFAs level >0.45 mmol/L in females and >0.6 mmol/L in males).
    keywords: baseline; cholesterol; fatty; ffas; free; insulin; level; patients; study
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        item: #3 of 59
          id: cord-003532-lcgeingz
      author: None
       title: 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019
        date: 2019-03-19
       words: 80115
      flesch: 48
     summary: Blood cultures were sent as per clinical & laboratory diagnosis of sepsis in ICU patients. Conclusions: HR, lactate levels and age before AVP initiation can predict the response to AVP in ICU patients with NE-resistant hypotension.
    keywords: acute; admission; age; aim; aki; analysis; arrest; arterial; assessment; baseline; blood; cardiac; care; care unit; cases; clinical; complications; conclusions; correlation; critical; data; days; diagnosis; difference; discharge; ecmo; effect; emergency; factors; failure; fig; figure; fluid; group; high; hospital; hospital mortality; hours; icu; icu admission; icu patients; ill; incidence; increase; injury; intensive; intervention; introduction; lactate; length; levels; low; lung; management; map; mean; median; medical; methods; months; mortality; non; organ; outcome; patients; patients introduction; period; post; pressure; rate; ratio; response; results; resuscitation; risk; score; sepsis; sepsis patients; septic; serum; severity; shock patients; sofa; stay; studies; study; surgery; survival; system; table; test; therapy; time; total; trauma; treatment; ultrasound; unit; use; ventilation; years
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        item: #4 of 59
          id: cord-004879-pgyzluwp
      author: None
       title: Programmed cell death
        date: 1994
       words: 81833
      flesch: 47
     summary: 8cl-2(z is a mitochondrial or perinuclear-associated oncoprotein that prolongs the life span of a variety of cell types by interfering with programmed cell death. Single and repetitive uptake and release of CPZ were measured in each cell type after individual exposure or exposure in any combination of cell types: In 2 hour competitive uptake studies fibreblasts reached 1.7 and 2.6 times the concentrations of C6-and ROC-cells, :respectively.
    keywords: acid; activation; activity; addition; adult; amino; analysis; animals; antibodies; binding; brain; calcium; cdna; cell lines; cells; changes; cloned; complex; concentrations; conditions; contrast; control; cultures; current; data; days; decrease; development; different; differentiation; dna; domain; early; effects; end; enzyme; epithelial; experiments; expression; extracts; factor; family; fold; form; formation; function; fusion; gene; gene expression; growth; homology; hormone; human; increase; induction; infected; inhibition; institut; interaction; intracellular; kda; kinase; levels; major; mammalian; mechanisms; medium; membrane; mice; molecular; mouse; mrna; muscle; mutant; nerve; neuronal; neurons; new; non; nuclear; nucleus; number; order; pathway; phosphorylation; play; positive; potential; presence; present; process; production; promoter; properties; protein; protein expression; rat; rate; rats; reaction; receptor; recombinant; recombination; region; regulation; release; replication; response; results; rna; role; sequence; signal; sites; species; specific; stage; stimulation; structure; studies; study; subunit; surface; synthesis; system; t cells; target; terminal; time; tissue; tnf; transcription; treatment; tumor; type; university; virus; vitro; vivo; yeast
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        item: #5 of 59
          id: cord-004948-ad3i9wgj
      author: None
       title: 7th International Congress on Amino Acids and Proteins : Vienna, Austria, August 6–10, 2001
        date: 2001
       words: 73789
      flesch: 41
     summary: After the performic acid oxidation and the 6 M HCl hydrolysis of the protein, OPA/TATG (o-phthaldialdehyde/tetra-O-acetyl-1-thio--D-glucopiranoside) precolumn derivatisation method was used, and the enantiomers of sulphur containing amino acids were separated by RP-HPLC (LiChrosphere 100 RP-18e, 125 ϫ 4 mm, 5 µm column, Merck-Hitachi LaChrom HPLC). The dominant ones are water, ethanol, glycerol, sugars, organic acids, and various ions, while amino acids are present at much lower concentration.
    keywords: acids; activation; activities; activity; addition; administration; amino acid; analysis; animals; antagonists; apoptosis; approach; arginine; binding; biological; blood; brain; cancer; cell; chain; changes; clinical; complex; compounds; concentration; conditions; content; control; cysteine; data; decrease; department; derivatives; development; disease; dna; dopa; effect; enzyme; ethanol; experiments; expression; following; formation; free; function; gaba; gel; gene; glucose; glutamate; glutamine; group; growth; human; identification; increase; inhibition; institute; leucine; levels; liver; lysine; mass; mechanism; membrane; metabolism; methionine; method; mice; model; molecular; mrna; new; nmda; non; number; patients; peptide; plasma; polyamines; present; production; properties; proteins; rats; reaction; receptor; reduced; release; research; response; results; role; samples; sequence; stress; structure; studies; study; substrate; synthesis; system; taurine; time; tissue; transport; treatment; tumor; type; university; uptake; vitamin; vitro; vivo
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        item: #6 of 59
          id: cord-005633-oyhpwut7
      author: Oppert, Michael
       title: Plasma cortisol levels before and during "low-dose" hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock
        date: 2000-11-18
       words: 3946
      flesch: 45
     summary: However, during hydrocortisone therapy cortisol levels did not differ between patients receiving and those not receiving hemodialysis or hemofiltration, with the exception of day 2, when free cortisol was even higher in patients on renal replacement therapy [1057 (802±1481) vs. 430 (290±924) nmol/l; p < 0.01]. key: cord-005633-oyhpwut7 authors: Oppert, Michael; Reinicke, Albrecht; Gräf, Klaus-Jürgen; Barckow, Detlef; Frei, Ulrich; Eckardt, Kai-Uwe title: Plasma cortisol levels before and during low-dose hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock date: 2000-11-18 journal: Intensive Care Med DOI: 10.1007/s001340000685 sha: doc_id: 5633 cord_uid: oyhpwut7 Objectives: To compare cortisol levels during low-dose hydrocortisone therapy to basal and ACTH-stimulated endogenous levels and to assess whether clinical course and the need for catecholamines depend on cortisol levels and/or pretreatment adrenocortical responsiveness.
    keywords: cortisol; hydrocortisone; levels; nmol; patients; production; therapy
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        item: #7 of 59
          id: cord-005646-xhx9pzhj
      author: None
       title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme
        date: 1996
       words: 72090
      flesch: 51
     summary: Objective: To assess the normal ,gastric intramucosal pH ~Hi) by tonometry in healthy children Patients and methods: Twelve healthy children (6 males and 6 females) with age rmaged from 6 months to 12 years scheduled for minor plastic or urologic surgery. Pain relief was good (VRS less 2) in 53 children -94.6 % of study patients.
    keywords: acute; administration; admission; age; airway; analysis; ards; arterial; average; babies; blood; brain; cardiac; care; cases; changes; chest; children; complications; conclusion; cpb; criteria; data; days; death; diagnosis; difference; disease; dose; drug; duration; ecmo; effects; failure; flow; gas; group; heart; high; hospital; hours; hypertension; icu; ill; incidence; increase; infants; infusion; initial; injury; intensive; levels; life; lung; management; mean; measurements; mechanical; median; medical; methods; minutes; months; mortality; neonatal; neonates; newborns; nitric; non; nurses; outcome; oxide; oxygenation; parameters; patients; peak; pediatric; period; phi; picu; plasma; post; present; pressure; prism; pulmonary; range; rate; response; results; risk; score; sepsis; severe; severity; study; support; surgery; survivors; syndrome; system; test; therapy; time; total; treatment; unit; use; values; ventilation; volume; weeks; weight; years
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        item: #8 of 59
          id: cord-005814-ak5pq312
      author: None
       title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts
        date: 1995
       words: 179325
      flesch: 51
     summary: Leukemia inhibitory factor (LIF), a growth factor recently recognised as a polyfunctional cytokine integrated in cytokine networks was measured in unconcentrated BALF of patients from different patient groups. It is difficult to generalize on intensive care units as different patient groups are in different ICUs aud there are great changes from one hospital to another and from one country to another.
    keywords: activity; acute; administration; admission; adult patients; age; aim; airway; analysis; apache; application; ards patients; arf; arterial; artery; assess; average; baseline; blood; blood flow; blood pressure; blood volume; breathing; cardiac; care patients; care unit; cases; catheter; cerebral; changes; chest; children; clinical; compliance; complications; concentration; conclusions; conditions; constant; control group; control patients; copd patients; correlation; course; cpb; criteria; critical; cvp; daily; damage; data; days; death; death patients; decrease; diagnosis; difference; disease; dose; drugs; duration; dysfunction; effect; emergency; end; evaluation; exchange; factors; failure; failure patients; findings; flow; fluid; following; frequency; function; gas; gastric; general; good; group; group b; group ii; group patients; h20; head; heart; hemodynamic; hepatic; hospital; hours; hypertension; icp; icu patients; iii; ill; illness; improvement; incidence; increase; index; infection; influence; infusion; injury; intensive; introduction; intubation; lactate; left; levels; life; liver; lung; male; management; map; mean; measurements; median; medical; methods; min; minutes; mmhg; model; monitoring; mortality; mortality rate; muscle; myocardial; need; negative; new; non; normal; number; objectives; onset; operation; order; organ; outcome; output; oxygen; oxygenation; p =; p<0.05; pao2; parameters; patients; patients methods; pattern; peep; perfusion; period; phase; phi; plasma; population; position; postoperative; presence; present; pressure; pressure support; procedure; protocol; pts; pulmonary; rain; range; rate; rats; reduction; renal; resistance; respiratory; response; results; right; risk; risk patients; samples; saps; score; sepsis; septic; serum; severe; severity; shock; shock patients; signs; specific; standard; status; stay; studies; study; study group; study period; subjects; support; surgery patients; surgical; survival; survivors; syndrome; system; systemic; technique; temperature; test; therapeutic; therapy; time; tissue; total; tracheal; transplantation; trauma patients; treatment; tube; type; unit; university; use; values; variables; vascular; vein; venous; ventilation; ventricular; volume; weaning; years
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        item: #9 of 59
          id: cord-006229-7yoilsho
      author: None
       title: Abstracts of the 82(nd) Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 18(th) Annual Meeting of the Network Clinical Pharmacology Germany (VKliPha) in cooperation with the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e.V. (AGAH)
        date: 2016-02-06
       words: 134020
      flesch: 40
     summary: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by a metabolic shift towards enhanced aerobic glycolysis and hence, increased lactate production. Further studies will be performed to clarify whether silver ions and/or silver nanoparticles could affect the specific N-acetylation of arylamines in human cells.
    keywords: acid; activation; activity; addition; agents; agonist; aim; analysis; animal; anti; approach; assay; assessment; background; barrier; binding; blood; body; brain; camp; cancer; cancer cells; cardiac; cell death; cell line; cells; cgmp; changes; channels; chemical; chronic; clinical; complex; compounds; concentrations; conclusion; conditions; contrast; control; culture; current; damage; data; days; death; development; differences; different; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; experiments; exposure; expression; factor; fibroblasts; findings; flow; fold; food; formation; fret; function; g protein; gene; germany; group; growth; health; heart; human; impact; increase; induction; inflammation; influence; inhibition; inhibitors; insulin; interaction; intracellular; kidney; levels; line; liver; loss; low; lung; mcpd; mechanisms; membrane; metabolism; metabolites; methods; mice; migration; model; mouse; mrna; nanoparticles; neurons; new; non; novel; number; oct1; order; p<0.05; parameters; pathways; patients; phosphorylation; plasma; platelet; potential; presence; present; primary; processes; products; proliferation; properties; protein; protein expression; rats; receptor; receptor activation; reduced; reduction; regulation; release; research; resistance; response; results; risk; role; samples; set; signaling; skin; small; specific; stimulation; stress; studies; study; substances; system; target; test; testing; therapy; time; tissue; total; toxicity; transcription; treatment; tumor; type; uptake; vitro; vivo; vs.; weight
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        item: #10 of 59
          id: cord-006230-xta38e7j
      author: None
       title: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V.
        date: 2012-02-22
       words: 136000
      flesch: 40
     summary: In in-vitro studies on rat and canine mast cells and human mast cell leukemia cells HMC1.2 BZ at micromolar concentrations inhibited mediator release which appeared to be related to an inhibition of the intracellular cAMP pathway. Previous work showed that mouse cells lacking the immediate-early gene c-fos are hypersensitive to ultraviolet (UVC) light.
    keywords: acid; activation; activity; acute; addition; adducts; agonist; aim; analysis; animals; anti; apoptosis; approach; assay; assessment; binding; blood; brain; calcium; camp; cancer; cancer cells; cardiac; cell line; cells; cellular; cgmp; changes; channels; chronic; clinical; complex; compounds; concentration; conclusion; conditions; contrast; control; current; damage; data; days; death; decrease; deficient; development; differences; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; evidence; experiments; exposure; expression; factor; failure; family; fibroblasts; findings; fold; food; formation; function; für; g protein; gene; gene expression; germany; glucose; growth; health; heart; human; hypertrophy; increase; induction; inflammation; inhibition; inhibitors; institut; insulin; interaction; intracellular; kidney; kinase; leads; levels; like; line; liver; loss; low; lung; macrophages; mechanisms; membrane; methods; mice; model; mouse; mrna; muscle cells; mutations; nanoparticles; ndpk; non; novel; number; pain; pathway; patients; pcr; pharmakologie; phosphorylation; plasma; potential; presence; present; pressure; primary; processes; production; products; proliferation; promoter; properties; protein; protein expression; pulmonary; rats; receptor; reduced; regulation; release; response; results; risk; rkip; role; ros; samples; selective; signaling; site; skin; smooth; specific; stimulation; stress; studies; study; substances; subunits; synthesis; system; t cells; target; test; tested; therapy; time; tissue; toxicity; toxikologie; toxin; transcription; transport; treatment; tumor; tumor cells; type; universität; uptake; values; vascular; vitro; vivo; water
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        item: #11 of 59
          id: cord-006391-esnsa4u5
      author: None
       title: Abstracts 5(th) Tripartite Meeting Salzburg/Austria, September 9–11,1982
        date: 1982
       words: 44873
      flesch: 47
     summary: Control patients (no ASA) were compared to those receiving 80 or 325 mg. After transplantation patients were followed for a minimum of 3 months and a maximum of 42 months.
    keywords: acid; activity; acute; animals; bile; blood; blood flow; body; bypass; cases; cells; changes; control; days; dogs; duct; effect; failure; flow; gastric; glucose; graft; group; heart; hepatic; increase; infusion; insulin; kidney; levels; liver; mean; method; min; months; non; normal; operation; patients; plasma; postoperative; present; pressure; rate; rats; rejection; response; results; serum; studies; study; surgery; survival; time; tissue; total; transplantation; treatment; tumor; values; vascular; weeks; weight
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        item: #12 of 59
          id: cord-006435-4o8uu6d5
      author: Kivity, Shaye
       title: Evidence for the Use of Intravenous Immunoglobulins—A Review of the Literature
        date: 2009-07-10
       words: 14153
      flesch: 21
     summary: Intravenous immunoglobulin treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis: a prospective noncomparative study showing no benefit on mortality or progression Treatment of toxic epidermal necrolysis. An update Sarova-Pinhas I (1998) Intravenous immunoglobulin treatment in multiple sclerosis.
    keywords: case; disease; dose; evidence; high; immune; immunoglobulin; immunoglobulin therapy; immunoglobulin treatment; intravenous; intravenous immunoglobulin; ivig; ivig treatment; level; patients; recommendation; recommendation iia; severe; strength; syndrome; therapy; treatment; use
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        item: #13 of 59
          id: cord-006860-a3b8hyyr
      author: None
       title: 40th Annual Meeting of the GTH (Gesellschaft für Thrombose- und Hämostaseforschung)
        date: 1996
       words: 90772
      flesch: 46
     summary: The data show that children with low risk did in part receive higher doses of heparin and/or AT III concentrate than did high risk patients, whereas plasma therapy was adjusted to severity of eoagnlopathy. Inhibitor testing was done on patients plasma samples using the Bethesda method.
    keywords: activation; activity; acute; addition; age; agents; aggregation; analysis; antibodies; anticoagulant; anticoagulation; antigen; antithrombin; apc; aptt; assay; binding; bleeding; blood; blood coagulation; blood samples; cases; cells; children; clinical; clotting; coagulation; coagulation factor; complex; complications; concentrations; conclusion; contrast; control; coronary; correlation; count; data; day; days; deficiency; diagnosis; disease; dose; effect; elevated; endothelial; events; expression; factor; factor v; factor viii; family; fibrin; fibrinogen; formation; group; heparin; hirudin; hours; human; incidence; increase; influence; infusion; inhibitor; inr; laboratory; levels; low; mean; median; method; months; mutation; normal; order; parameters; patients; period; phase; plasma; plasma samples; plasminogen; platelet; platelet activation; platelet factor; present; products; protein; protein c; prothrombin; pts; range; reagent; receptor; reduced; release; resistance; response; results; risk; risk factor; role; samples; specific; studies; study; surface; surgery; system; test; therapy; thrombin; thrombosis; time; tissue; total; treatment; type; use; values; vascular; vein; venous; viii; vwf; weight; years
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        item: #14 of 59
          id: cord-011360-1n998win
      author: Zloto, Keren
       title: Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery
        date: 2019-11-15
       words: 3411
      flesch: 37
     summary: Patients with higher postoperative lactate values had lower preoperative miRNA-208a levels. We tested whether preoperative levels of miRNAs-208a can serve as such a biomarker.
    keywords: complications; heart; levels; mirna-208a; patients; preoperative; surgery
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        item: #15 of 59
          id: cord-015021-pol2qm74
      author: None
       title: Third International Congress on the Immune Consequences of Trauma, Shock and Sepsis —Mechanisms and Therapeutic Approaches
        date: 1994
       words: 162543
      flesch: 45
     summary: Ever since we know the role of endotoxins in the pathophysiology of sepsis, antibodies against the S-and R-LPS have also been detected in sepsis patients. In sepsis patients, the CD]4+/CD16+ cells can become a major population with more than 50% of all monocytes in 3 of 18 patients and with more than 500 cells/mm 3 in 4 of 18 cases.
    keywords: acid; activation; activity; acute; addition; adhesion; administration; aim; analysis; animals; anti; antibodies; antibody; ards; arterial; bacteria; binding; blood; blood cells; blood levels; blood samples; body; burn; capacity; cardiac; cause; cd14; cells; cellular; challenge; changes; circulating; clinical; clp; complement; complications; concentrations; conclusion; conditions; contrast; control; control group; control patients; correlation; course; csf; cultured; cytokine levels; cytokine production; cytokines; damage; data; days; death; decrease; development; differences; disease; dose; dysfunction; effect; elevated; elisa; endothelial; endotoxin; endotoxin levels; evidence; experimental; expression; factor; failure; flow; following; formation; function; gene; gram; group; growth; gut; hepatic; high; host; hours; hrs; human; il-1; il-6; il-6 levels; il-8; ill; immune; increased; induction; infection; inflammation; inflammatory; infusion; inhibitor; injury; ischemia; leukocytes; levels; lipid; liver; lps; lung; lymphocytes; macrophages; mean; mechanisms; mediators; membrane; methods; mice; model; mof; molecules; monoclonal; monocytes; mortality; multiple; necrosis; negative; neutrophils; new; non; normal; number; operation; organ; organ failure; organ injury; outcome; oxygen; p<0.05; parameters; patients; period; peritoneal; phase; placebo; plasma; plasma levels; plasma tnf; play; pmn; positive; post; postoperative; potential; presence; present; pressure; process; production; protein; pulmonary; rate; rats; receptor; reduced; related; release; reperfusion; response; results; risk; role; saline; samples; score; sepsis; sepsis patients; septic; serum; serum levels; severity; sham; shock; sirs; soluble; specific; state; stimulation; studies; study; surface; surgery; survival; syndrome; synthesis; system; systemic; t cells; test; therapeutic; therapy; time; tissue; tnf; tnf levels; tnf production; tnf release; total; trauma patients; treated; treatment; tumor; type; use; values; vascular; vitro; vivo; wound
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        item: #16 of 59
          id: cord-015024-2xzc0uc5
      author: None
       title: ESICM 2010 WEDNESDAY SESSIONS 13 October 2010
        date: 2010-08-31
       words: 84465
      flesch: 50
     summary: The primary end point of this study was to evaluate the RVD of the IVC in ICU patients with spontaneous breathing. ICU patient with spontaneous breathing and signs of hypoperfusion (oliguria, mottles, serum lactate level [2 mmol/l) were eligible after the approval of the local Ethics Committee.
    keywords: acute; administration; admission; age; aim; analysis; apache; baseline; blood; cardiac; care; care patients; care unit; changes; clinical; conclusions; control; critical; data; day; days; death; difference; discharge; dose; effect; factors; failure; fluid; following; function; group; hemodynamic; high; hospital; icu admission; icu patients; incidence; increase; infusion; injury; intensive; introduction; levels; low; lung; management; mean; median; medical; methods; min; months; mortality; n =; non; number; nurses; objectives; outcome; p =; parameters; patients; period; plasma; post; pressure; pulmonary; rate; response; results; resuscitation; risk; score; sepsis; septic; serum; shock; shock patients; stay; study; support; surgery; test; therapy; time; total; treatment; unit; use; values; ventilation; volume; years
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        item: #17 of 59
          id: cord-015082-l629n8is
      author: None
       title: Poster Sessions 323-461
        date: 2002-08-29
       words: 26609
      flesch: 50
     summary: Isoflurane sedation of ICU patients has previously been shown to be useful but has not come into wide clinical use for a number of reasons. Isoflurane administered via the ACD for sedation of ICU patients is environmentally safe, requires small volumes of isoflurane and may provide better quality of sedation than midazolam.
    keywords: acute; admission; age; analysis; blood; cardiac; care; complications; control; data; days; effect; group; hospital; hours; icu; increase; injury; levels; mean; methods; min; mortality; outcome; patients; postoperative; pressure; protein; rate; rats; response; results; score; sepsis; septic; shock; stay; study; surgery; test; time; trauma; treatment; years
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        item: #18 of 59
          id: cord-015090-n6f4xupw
      author: None
       title: PS 339-563
        date: 2005-09-10
       words: 26303
      flesch: 51
     summary: Propofol is often used as a sedative in ICU patients. The aim of this study was to suggest how the computation of ÄSID should be sophisticated in order to obtain a good correspondence with BE in ICU patients.
    keywords: admission; age; aim; analysis; blood; brain; cardiac; care; cases; changes; conclusion; costs; data; days; group; hospital; hours; icu; intensive; levels; mean; medical; methods; mortality; non; organ; outcome; patients; period; pressure; rate; risk; score; sepsis; shock; stay; study; surgery; test; time; trauma; tube; unit; university; use; ventilation
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        item: #19 of 59
          id: cord-015147-h0o0yqv8
      author: None
       title: Oral Communications and Posters
        date: 2014-09-12
       words: 73903
      flesch: 39
     summary: After 3 months of exposures, inflammatory cells in bronchoalveolar lavage fluid were increased in both the HCR-and LCR-smokeexposed(SE) animals compared to air-exposed controls (p<0.001); however there was a 2-3-fold increase in the number of neutrophils and lymphocytes in the LCR-over the HCR-SE group (p<0.001).Histopathology revealed there was greater inflammation and lung damage present in the LCR-versus HCR-SE group (p<0.05). This causes the symptoms of the early phase of AI and the onset of the late phase characterized by the penetration in the inflamed tissue of inflammatory cells, notably the eosinophils.
    keywords: activation; activity; acute; addition; adhesion; administration; aim; alpha; analysis; animals; anti; antibodies; antibody; arthritis; associated; beta; binding; blood; bone; cancer; cartilage; cells; chronic; complex; conditions; control; cox-2; cytokines; data; day; days; development; disease; dose; effect; expression; factor; function; gene; group; hours; human; il-1b; il-6; immune; increase; induction; inflammation; inflammatory; inhibited; inhibition; inhibitors; injection; injury; joint; kinase; leukocyte; levels; lps; lung; macrophages; mechanisms; mediators; methods; mice; mif; model; molecular; molecules; monocytes; mouse; mrna; neutrophils; new; novel; number; p38; pathways; patients; pcr; plasma; potential; presence; present; production; protein; rats; receptor; reduced; regulation; release; research; response; results; rheumatoid; role; selective; serum; signaling; skin; specific; stimulation; studies; study; synthesis; system; t cells; therapeutic; time; tissue; tnf; tnfa; treatment; tumor; type; university; vitro; vivo
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        item: #20 of 59
          id: cord-015306-us58wwmp
      author: None
       title: Abstracts for the IPNA Congress, 30 August - 3 September 2013, Shanghai, China
        date: 2013-06-21
       words: 71292
      flesch: 48
     summary: The purpose of this study was to determine the diagnostic performance of the application of questionnaires to detect ADHD and other psychiatric disorders in children with functional voiding disorders in general pediatrics consultations Methods: The study was conducted on 32 children between 6 and 13 years of age (20 males) diagnosed with FVD (patient group) and 32 children of the same age (21 males) who had no urinary symptoms (control group). Conclusion: Converting from a CNI based immunosuppressant protocol for Paediatric renal transplantation patients to a Sirolimus based one was effective and the benefit was shown up to 54 months post-transplantation One patient received a desensitisation regime with Rituximab and plasmaexhange pre-transplant and IV immunoglobulin post-operatively.
    keywords: abstract; acute; age; aki; analysis; biopsy; bladder; blood; cases; cells; children; chronic; ckd; conclusion; control group; correlation; creatinine; data; days; dialysis; difference; disease; dose; ebv; effect; enuresis; expression; factors; failure; findings; follow; function; gene; glomerular; grade; graft; group; group b; growth; hospital; hsp; igan; infection; injury; kidney; kidney disease; kidney injury; levels; mean; median; medical; methods; model; months; mutations; nephrology; nephropathy; nocturnal; non; objective; patients; pediatric; period; post; primary; proteinuria; range; rate; rats; recipients; renal; results; risk; role; serum; stage; study; study group; survival; syndrome; term; therapy; time; total; transplantation; treatment; treatment group; tubular; university; urinary; urine; vur; weeks; weight; years
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        item: #21 of 59
          id: cord-015372-76xvzvdg
      author: None
       title: National scientific medical meeting 1996 abstracts
        date: 1996
       words: 36628
      flesch: 50
     summary: Control patients were enrolled who had no clinical evidence of rheumatological disease, A salivary sample was collected and examined by light microscopy. Drug induced photosensitivity may look identical clinically, have a similar history and patients with CAD may be treated with potentially photosensitising drugs.
    keywords: acid; activity; age; aim; analysis; antibodies; blood; bone; care; cases; cells; children; controls; data; day; difference; disease; drug; expression; females; findings; following; group; hiv; hospital; incidence; increase; infection; irish; levels; males; mean; months; negative; number; pain; patients; pcr; period; population; positive; present; range; rate; response; results; risk; samples; serum; skin; studies; study; subjects; test; therapy; time; total; treatment; type; use; virus; years
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        item: #22 of 59
          id: cord-015394-uj7fe5y6
      author: None
       title: Scientific Abstracts
        date: 2008-12-23
       words: 242809
      flesch: 48
     summary: The highest level of -tubulin acetylation (2.5-fold) was observed with Vinblastine at 10-fold IC 50 after 48 h. Exposure to Microtubule interacting agents and TSA resulted in increased cell surface expression of Ep-CAM in a time and dose dependent manner. Finally, we elucidated a link between the RA and TGF-pathways by assessing the impact of RA treatment of TGF-3 expression, demonstrating that TGF-3 template decreased to levels comparable to myometrial cell expression (0.84±0.12 fold).
    keywords: acid; activation; activity; addition; administration; adult; aea; age; aim; analysis; animals; anova; anti; antibodies; antibody; apoptosis; arteries; artery; assay; associated; association; background; baseline; binding; birth; blood; blood cells; blot; bmi; body; brain; cancer; cancer cells; cases; cells; center; cervix; cesarean; changes; clinical; collagen; concentrations; conclusions; conditions; contractions; contrast; contribute; control; control cells; control group; correlation; cortisol; crf; culture; cycle; cytokines; data; day; days; decidua; decrease; delivery; design; development; differences; differentiation; disease; dna; dose; effect; elisa; endometriosis; endometrium; endothelial; eoc cells; epithelial; estradiol; estrogen; evidence; explants; exposure; expression; expression levels; factor; fat; female; fetal; fetuses; findings; flow; fluid; fold; following; free; function; gene; gestation; glucose; gnrh; group; growth; gynecology; hcg; high; hormone; hospital; hours; human; hypertension; hypothesis; hypoxia; il-6; il-8; immune; immunohistochemistry; implantation; increase; induction; infection; inflammation; inhibitor; insulin; introduction; invasion; iugr; ivf; kinase; labor; leptin; levels; lps; male; maternal; mean; mechanisms; media; medical; medicine; medium; membranes; menstrual; methods; mice; min; model; mouse; mrna expression; mrna levels; muscle cells; myometrial; n=6; neonatal; new; non; normal; novel; nuclear; number; obesity; objective; obstetrics; offspring; onset; oocytes; outcome; ovarian; oxygen; p<0.001; p<0.05; pathway; patients; pattern; pcos; pcr; period; phase; phosphorylation; placental; placental cells; plasma; play; population; positive; post; potential; preeclampsia; pregnancies; pregnancy; pregnant; presence; present; pressure; preterm; primary; production; progesterone; proliferation; protein expression; protein levels; proteins; range; rate; rats; receptor; receptor expression; reduced; regulation; relative; release; reproductive; response; restriction; results; risk; role; samples; secretion; sections; serum; sheep; signaling; smooth; specific; staining; stress; studies; study; study group; subjects; syndrome; system; t cells; term; test; time; tissue; tnf; total; treatment; trimester; trophoblast cells; tumor; type; university; usa; uterine; uterus; vascular; vegf; vehicle; vitro; vivo; weeks; weight; western; women; years
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        item: #23 of 59
          id: cord-016300-vw11c2wt
      author: Jain, Kewal K.
       title: Biomarkers of Pulmonary Diseases
        date: 2017-09-18
       words: 5584
      flesch: 38
     summary: Lung ECM remodeling in healthy controls and COPD patients was investigated in the COPDGene study. One study was done to quantify bronchial lavage (BAL) fluid and serum levels of IL-8, secretory leukocyte protease inhibitor (SLPI), soluble intracellular adhesion molecules-1 (sICAM-1) and sCD14, as surrogate markers of inflammatory and immune response in asthma and COPD patients with similar disease duration time (Hollander et al. 2007 ).
    keywords: airway; asthma; biomarkers; copd; disease; function; inflammation; levels; lung; patients; serum
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        item: #24 of 59
          id: cord-017309-pt27efu1
      author: Gupta, G. S.
       title: Selectins and Associated Adhesion Proteins in Inflammatory disorders
        date: 2012-03-20
       words: 25465
      flesch: 31
     summary: Effect of extracellular pH Genomic rearrangements on VCAM1, SELE, APEG1and AIF1 loci in atherosclerosis Lp95, a novel leptospiral protein that binds extracellular matrix components and activates E-selectin on endothelial cells Genetic polymorphisms in cytokine and adhesion molecule genes in coronary artery disease E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release Regulation of gene expression by a-tocopherol E-selectin, and P-selectin expressions in papillary thyroid carcinomas and their correlation with prognostic parameters A novel antiinflammatory role for andrographolide in asthma via inhibition of the nuclear factor-kB pathway Platelet P-selectin and GPIIb/IIIa expression after liver transplantation and resection Selectin inhibitors: a patent review The involvement of the sLe-a selectin ligand in the extravasation of human colorectal carcinoma cells Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury Plasma indices of endothelial and platelet activation in Rheumatoid Disease: relationship to cardiovascular co-morbidity Soluble intercellular adhesion molecule-1 and E-selectin in patients with asthma exacerbation Selectins and monocyte chemotactic peptide as the markers of atherosclerosis activity Soluble adhesion molecules in pediatric rheumatic diseases Impact of prolonged cyclooxygenase-2 inhibition on inflammatory markers and endothelial function in patients with ischemic heart disease and raised Creactive protein: a randomized placebo-controlled study Antimetastatic activities of modified heparins: selectin inhibition by heparin attenuates metastasis Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanase TNF-a blockade induces a reversible but transient effect on endothelial dysfunction in patients with long-standing severe rheumatoid arthritis Transcriptional arrest of the human E-selectin gene Expression of E-selectin and its transcripts during intestinal ischemia-reperfusion injury in pigs The antitumor activity of an anti-CD54 antibody in SCID mice xenografted with human breast, prostate, non-small cell lung, and pancreatic tumor cell lines Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress Invasive amebiasis: A microcirculatory disorder? P-selectin knockout mice have improved outcomes with both warm ischemia and small bowel transplantation Soluble E-selectin in children and adolescents with type 1 diabetes Blocking E-selectin inhibits ischaemiareperfusion-induced neutrophil recruitment to the murine testis Increased platelet CD63 and Pselectin expression persist in atherosclerotic ischemic stroke Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro Increased plasma levels of soluble P-selectin in rheumatic mitral stenosis The common variants of E-selectin gene in Graves' disease Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease Pathogenic aspects of pulmonary complications in acute pancreatitis patients Effect of rosiglitazone treatment on circulating vascular and inflammatory markers in insulin-resistant subjects Changes in Pselectin expression on cardiac microvessels in blood-perfused rat hearts subjected to ischemia-reperfusion Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells Successful treatment of rheumatoid arthritis is associated with a reduction in serum sEselectin and thrombomodulin level Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice Circulating E-selectin and tumor necrosis factor-alpha in extraarticular involvement and joint disease activity in rheumatoid arthritis Protein biochip array of adhesion molecule expression in peripheral blood of patients with nasal polyposis Serum P-selectin, soluble vascular cell adhesion molecule-I (s-VCAM-I) and soluble intercellular adhesion molecule-I (s-ICAM-I) levels in bladder carcinoma patients with different stages Autoantibodies and other serological markers in rheumatoid arthritis: predictors of disease activity? Phenyl methimazole inhibits TNF-a-induced VCAM-1 expression in an IFN regulatory factor-1-dependent manner and reduces monocytic cell adhesion to endothelial cells Changes in endogenous cytokines, adhesion molecules and platelets during cytokine-induced tumor necrosis Evaluation of sE-Selectin and sICAM-1 as parameters for renal function ICAM1 R241 is not associated with celiac disease in the Spanish population Comparative study of adhesion molecule expression in nodular lesions of Behçet syndrome and other forms of panniculitis Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications Circulating levels of soluble adhesion molecules in patients with ANCA-associated vasculitis Plasma cytokine and P-selectin levels in advanced malignancy: prognostic value and impact of low-molecular weight heparin administration Circulating adhesion molecules and purine nucleotides during kidney allograft reperfusion P-selectin-targeting of the fibrin selective thrombolytic Desmodus rotundus salivary plasminogen activator alpha1 E-and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice Cell adhesion molecules, vascular endothelial growth factor, and basic fibroblast growth factor in patients with non-small cell lung cancer treated with chemotherapy with or without bevacizumab-an Eastern Cooperative Oncology Group Study Does colorectal cancer clinical advancement affect adhesion molecules (sP-selectin, sE-selectin and ICAM-1) concentration? Soluble P-selectin concentration in patients with colorectal cancer Serum levels of soluble E-selectin are associated with the clinical course of metastatic disease in patients with liver metastases from breast cancer Markers for endothelial activation during open heart surgery Cell adhesion molecules-update Expression of selected adhesion molecules in dermatitis herpetiformis and bullous pemphigoid Differential induction of mRNA for ICAM-1 and selectins in hepatocytes, Kupffer cells and endothelial cells during endotoxemia Serum concentrations of sICAM-1, sE-, sP-and sL-selectins in patients with Schistosoma mansoni infection and association with disease severity Biochemical markers of endothelial activation in primary hyperparathyroidism Markers of low-grade inflammation and soluble cell adhesion molecules in Chinese patients with coronary artery disease Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians Selectins in the HIT syndrome: pathophysiologic role and therapeutic modulation Disruption of Pselectin signaling modulates cell trafficking and results in improved outcomes after mouse warm intestinal ischemia and reperfusion injury CD62 blockade with P-Selectin glycoprotein ligand-immunoglobulin fusion protein reduces ischemia-reperfusion injury after rat intestinal transplantation Independent pathways of P-selectin and complement-mediated renal ischemia/reperfusion injury IFN-g inhibits double-stranded RNAinduced E-selectin expression in human endothelial cells Candidate gene analysis of selectin cluster in patients with multiple sclerosis Enhanced expression of E-selectin on the vascular endothelium of peripheral nerve in critically ill patients with neuromuscular disorders A high frequency African coding polymorphism in the N-terminal domain of ICAM-1 predisposing to cerebral malaria in Kenya ICAM-1-dependent pathways regulate colonic eosinophilic inflammation Role of inflammation in diabetic nephropathy Circulating endothelial cells and rheumatoid arthritis: relationship with plasma markers of endothelial damage/dysfunction Variation in the ICAM1 gene is not associated with severe malaria phenotypes Interactions of the gastrotropic bacterium Helicobacter pylori with the leukocyteendothelium adhesion molecules, the selectins-A preliminary report Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells P-Selectin-mediated acute inflammation can be blocked by chemically modified heparin, RO-heparin Selectin blockade plus therapy with low-dose sirolimus and cyclosporin A prevent brain death-induced renal allograft dysfunction Microvascular endothelial cells from E-selectin-deficient mice form tubes in vitro Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease Retinoic acid inhibits the regulated expression of vascular cell adhesion molecule-1 by cultured dermal microvascular endothelial cells Leukocyte and endothelial cell adhesion molecules in inflammation focusing on inflammatory heart disease Putative outer membrane proteins of Leptospira interrogans stimulate human umbilical vein endothelial cells (HUVECS) and express during infection Expression of adhesion molecules in lungs of mice infected with Paracoccidioides brasiliensis conidia Circulating P-,L-and E-selectins in pseudoxanthoma elasticum patients Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis Angiotensin receptor blockade decreases markers of vascular inflammation Implication of adhesion molecules in inflammation of the common bile duct in patients with secondary cholangitis due to biliary obstruction Serum levels of intercellular adhesion molecule ICAM-1 and E-selectin in advanced stage non-small cell lung cancer E-selectin genetic variation as a susceptibility factor for ischemic stroke E-selectin gene induction by ionizing radiation is independent of cytokine induction Nuclear factor kappaB dominant negative genetic constructs inhibit X-ray induction of cell adhesion molecules in the vascular endothelium Strategies to reduce oxidative stress in cardiovascular disease Variant isoforms of CD44 are P-and L-selectin ligands on colon carcinoma cells Soluble cell adhesion molecules in gingival crevicular fluid in periodontal health and disease E-selectin gene S128R polymorphism is associated with poor prognosis in patients with stage II or III colorectal cancer Role of adhesion molecules in the induction of restenosis after angioplasty in the lower limb The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction Tumor necrosis factor-alpha upregulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways In vivo imaging of cutaneous T-cell lymphoma migration to the skin Injury of the blood brain barrier and up-regulation of ICAM-1 in polymicrobial sepsis Expression of chemokines and adhesion molecules in human coronary artery endothelial cells infected with Chlamydia (Chlamydophila) pneumoniae Pravastatin limits radiation-induced vascular dysfunction in the skin Thrombosis and atherosclerosis Endothelial microparticles as markers of endothelial dysfunction E-selectin and Lselectin polymorphisms in patients with periodontitis Endothelial activation and systemic inflammation in obese asthmatic children Bosentan regulates the expression of adhesion molecules on circulating T cells and serum soluble adhesion molecules in systemic sclerosisassociated pulmonary arterial hypertension Significance of endothelial molecular markers in the evaluation of the severity of acute pancreatitis Serum levels of P-selectin in men with high-functioning autism The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis Immunohistochemistry, glycosylation and immunosuppression of glycodelin in human ovarian cancer The role of the platelet in the pathogenesis of atherothrombosis Differential metastasis inhibition by clinically relevant levels of heparins-correlation with selectin inhibition, not antithrombotic activity Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells.
    keywords: acid; activation; activity; adhesion; adhesion molecules; atherosclerosis; blood; cancer; cell adhesion; cells; chronic; disease; effect; endothelial; et al; expression; factor; gene; heparin; icam-1; increase; inflammation; inhibition; injury; interactions; leukocyte; levels; ligand; liver; markers; metastasis; mice; molecules; patients; plasma; platelet; polymorphism; protein; risk; role; selectin; serum; sle; surface; tnf; tumor; type; vascular
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        item: #25 of 59
          id: cord-018414-6ffhm895
      author: Kang, Yoogoo
       title: Anesthesia Management of Liver Transplantation
        date: 2016-07-22
       words: 21167
      flesch: 28
     summary: Liver transplantation requires a true multidisciplinary approach, and anesthesiologists and intensivists have played a major role in the successful outcome of liver transplantation. Right ventricular function during orthotopic liver transplantation Adult respiratory distress syndrome secondary to endstage liver disease-successful outcome following liver transplantation Use of intraoperative blood salvage during orthotopic liver transplantation Compression of the brachial plexus injury during right lobe liver donation as a cause of brachial plexus injury: a case report Rapid infusion devices for hemorrhagic cardiothoracic trauma Liver transplantation: effect of washing bank blood on intraoperative control of hyperkalemia Right heart dysfunction, pulmonary embolism, and paradoxical embolization during liver transplantation.
    keywords: administration; anesthesia; arterial; artery; blood; bypass; cardiac; coagulation; disease; dysfunction; et al; factors; failure; flow; function; hepatic; hypertension; ivc; level; liver; liver disease; liver transplantation; loss; output; patients; portal; pressure; reperfusion; right; serum; stage; syndrome; transplantation; vascular; vein; venous
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        item: #26 of 59
          id: cord-018623-of9vx7og
      author: Saghazadeh, Amene
       title: The Physical Burden of Immunoperception
        date: 2019-04-27
       words: 5764
      flesch: 31
     summary: For example, emotional stress is ranked as the second most common neuropsychological cause of acute myocardial infarction (AMI) owing to its record in approximately 40-50% of these patients [30, 31] . A possible pathogenic pathway for metabolic syndrome is initiated by emotional stress and ensuing enhancement in the levels of proinflammatory cytokines, e.g., IL-1, IL-6, and TNF-α.
    keywords: activity; anxiety; behaviors; cytokines; disease; expression; il-6; levels; mice; model; patients; personality; stress; type
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        item: #27 of 59
          id: cord-022070-soqeje4z
      author: Parry, Christopher M.
       title: Microbiology
        date: 2019-05-28
       words: 3698
      flesch: 34
     summary: International organizations are actively working with local and national providers to improve laboratory services. The development of laboratory services will contribute to improved health for the local population, protection against emerging pathogens, and ensure better use of scarce health care resources.
    keywords: care; health; infections; laboratories; laboratory; level; quality; tests; tuberculosis
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        item: #28 of 59
          id: cord-022353-q2k2krnm
      author: W. Quimby, Fred
       title: Clinical Chemistry of the Laboratory Mouse
        date: 2007-09-02
       words: 30268
      flesch: 42
     summary: Although we hope all readers of this chapter will benefit from this section on assays and instruments, the primary purpose of this chapter is to briefly introduce the reader to areas where methods in clinical chemistry are changing and provide sources of information for services, reagents (including test kits), and instrumentation, specifically for testing biomarkers (including traditional analytes) in mouse serum, plasma, or urine. Growth in the number of reagents capable of quantitating analytes in mouse serum is illustrated in Table 6 -2.
    keywords: acid; activity; addition; age; analytes; assays; atherosclerosis; binding; biomarkers; blood; cells; chemistry; chemokines; cholesterol; complement; corticosterone; development; disease; effects; elisa; enzyme; et al; expression; factor; function; gene; glucose; growth; hdl; hepatic; hormone; human; insulin; kits; ldl; levels; liver; metabolism; mice; mouse; murine; muscle; new; plasma; production; protein; quimby; receptor; response; role; secretion; serum; strains; surface; tissue; total; transgenic; type
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        item: #29 of 59
          id: cord-022633-fr55uod6
      author: None
       title: SAEM Abstracts, Plenary Session
        date: 2012-04-26
       words: 147610
      flesch: 49
     summary: Objectives: To identify the prevalence of NCS and other EEG abnormalities in ED patients with AMS. Objectives: Test the hypothesis that prior to antibiotic administration, circulating LPS can be detected in the plasma of fewer than 10% of ED patients with severe sepsis.
    keywords: academic; acute; admission; adult ed; adult patients; age; analysis; arrest; arrest patients; assessment; association; average; background; blood; cardiac; care; cases; center; change; characteristics; chest; children; clinical; cohort; conclusion; confidence; control; cpr; criteria; data; days; department; diagnosis; difference; discharge; disease; ed care; ed patients; ed physicians; ed visits; eds; effect; emergency; emergency department; ems; evaluation; factors; following; group; health; high; hospital; hospital ed; hours; implementation; increase; information; initial; injury; inpatient; intervention; intubation; length; level; los; low; management; mean; median; medical; medicine; methods; minutes; model; months; mortality; n =; non; number; objectives; outcomes; overall; p =; pain; pain patients; participants; pediatric; performance; period; population; post; pre; prehospital; primary; prior; program; protocol; providers; quality; range; rate; regression; research; residency; residents; respectively; results; retrospective; review; risk; sample; score; screening; self; sepsis; setting; shock; standard; students; studies; study; study ed; subjects; survey; survival; system; table; test; testing; time; total; training; trauma patients; treatment; triage; urban; use; years
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        item: #30 of 59
          id: cord-022650-phsr10jp
      author: None
       title: Abstracts TPS
        date: 2018-08-14
       words: 119916
      flesch: 51
     summary: Method: Postal questionnaires were distributed to an unselected group of asthma patients (n = 190). NHR was reported in 71% of asthma patients and 22% in non-asthmatic controls (P < 0.0001), with changes in temperature being the most important inducer of nasal symptoms (74% of asthmatics), followed by strong odours (62%) and cigarette smoke (61%).
    keywords: adults; age; aim; allergen; allergies; allergy; analysis; anaphylaxis; angioedema; anti; ara; asthma; asthma control; asthma patients; asthma symptoms; asthmatic; atopic; background; blood; case; cells; challenge; children; chronic; clinic; concentration; conclusion; control; control group; correlation; cross; data; days; dermatitis; diagnosis; differences; disease; dose; drug; dust; effect; efficacy; egg; episodes; exposure; extracts; factors; food; food allergy; grass; group; hae; high; history; hospital; hours; house; ige; ige levels; igg; immunotherapy; improvement; increase; levels; life; low; male; mean; median; medical; medication; method; milk; minutes; mite; months; nasal; non; number; p 1; p =; patients; peanut; period; pollen; pollen allergy; population; positive; present; prevalence; prick; protein; questionnaire; rate; reaction; reactivity; reduction; report; respiratory; response; results; rhinitis; rhinitis patients; risk; scit; score; sensitization; serum; severity; sige; skin; skin prick; slit; specific; spt; studies; study; subjects; symptoms; syndrome; test; testing; time; total; treatment; type; urticaria; use; weeks; years
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        item: #31 of 59
          id: cord-022653-qa1uph35
      author: None
       title: Poster Discussion Session PDS
        date: 2017-08-30
       words: 58403
      flesch: 49
     summary: Out of all maxillary sinuses (n=72) from study patients, 62 (86.11%) were opacified, and only these sinuses were included in further analyses. We studied three groups of subjects: peach allergic patients who received Prup3-enriched-SLIT for 1 year, peach allergic patients non treated, and healthy controls who tolerated peach.
    keywords: age; aim; allergen; allergic; allergy; analysis; anaphylaxis; anti; associated; asthma; asthma patients; atopic; blood; cases; cells; changes; children; conclusions; control; correlation; data; diagnosis; differences; disease; dose; drug; effect; exposure; expression; food; food allergy; group; hdm; healthy; history; ige; ige levels; immune; immunotherapy; increase; inflammation; introduction; levels; low; mean; methods; mice; milk; months; nasal; non; number; objectives; patients; period; pollen; production; protein; reactions; reactivity; response; results; rhinitis; risk; samples; score; sensitization; serum; skin; slit; specific; studies; study; subjects; symptoms; test; therapy; time; total; treatment; use; years
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        item: #32 of 59
          id: cord-022940-atbjwpo5
      author: None
       title: Poster Sessions
        date: 2016-09-07
       words: 241687
      flesch: 44
     summary: Among used cancer cell lines, ERICD was highly expressed and ARID3A had lower expression in U-2OS (osteosarcoma), A-172 (glioblastoma) and A549 (lung cancer). Clear cell renal cell cancer (ccRCC) with metastases has pour prognosis: 5-year survival is about 9%.
    keywords: a549 cells; acid; activation; activities; activity; activity levels; acute; addition; administration; affinity; agents; aim; albumin; allele; alterations; alternative; amino; analysis; analysis results; animals; ankara; anti; antibodies; antibody; anticancer; antioxidant; apoptosis; applications; approach; assay; association; bacteria; beta; binding; biology; blood; body; bone; brain; breast cancer; cancer cells; cancer group; cancer patients; cancer stem; cancer treatment; cancers; cause; cell cycle; cell death; cell growth; cell lines; cell proliferation; cell survival; cell viability; changes; characterization; chemical; cholesterol; chronic; clinical; coli; colorectal; combination; comparison; complex; complexes; compounds; concentrations; conclusion; conditions; content; control cells; control group; control study; controls; correlation; culture; curcumin; current; cytotoxic; damage; data; day; days; decrease; department; detection; determination; development; diabetes; differences; differentiation; discussion; disease; dna; domain; dose; drug; effects; elevated; elisa; energy; enzyme; enzyme activity; ethanol; experimental; expression analysis; expression levels; expressions; extract; factor; faculty; family; fat; findings; flow; fluorescence; fold; food; formation; free; function; gene expression; genes; genetic; genome; genotype; glucose; glutathione; group; growth; gsh; health; hours; human; immune; increase; inflammation; inflammatory; inhibition; inhibitors; injury; institute; insulin; interaction; intracellular; introduction; invasion; investigation; ischemia; kinase; laboratory; lead; levels; light; like; lipid; liver; low; lung; male; manner; markers; mass; materials; matrix; mcf-7; mda; mda levels; mean; mechanisms; medical; medicine; medium; membrane; metabolism; methods; methylation; mice; microscopy; migration; mirnas; mitochondrial; model; modified; molecular; molecules; mrna; muscle; mutant; mutations; n =; nanoparticles; negative; non; normal; novel; number; obese; obesity; oil; order; oxidative; oxygen; p =; p-02.08.5; parameters; pathway; patients; pcr; peptide; phase; plant; plasma; play; point; polymorphisms; population; potential; presence; present; process; processes; production; products; profile; progression; promoter; properties; prostate; prostate cancer; protective; protein; protein expression; protein levels; purpose; radical; range; rate; rats; reaction; receptor; recombinant; region; regulation; related; relationship; research; resistance; response; results; risk; role; samples; science; scientific; screening; sequence; serum; serum levels; signaling; site; size; sod; species; specific; stability; stage; status; stem cells; strain; stress; structure; studies; study; study group; subjects; surface; survival; synthesis; system; target; technique; temperature; test; tested; therapeutic; therapy; time; tissue; tnf; total; transcription; treatment; treatment group; tumor; tumor cells; turkey; type; university; use; values; vitamin; vitro; water; weight; western; wild; women; work; years
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        item: #33 of 59
          id: cord-023157-0lqlx2rv
      author: None
       title: Poster Sessions
        date: 2013-04-18
       words: 128609
      flesch: 50
     summary: Results: Mean values of WC, blood pressure (BP), fasting plasma glucose (FPG), triglycerides (TG), HDL-Cholesterol and BMI were significantly higher in men than in women who had higher %BF (28% vs. 21%). Results: During IvGTT GBP-pigs displayed lower glucose and higher insulin levels compared to controls.
    keywords: 0.001; acid; activity; adiponectin; adipose; age; aim; analysis; association; background; baseline; blood; blood glucose; blood pressure; bmi; body; body weight; cardiovascular; changes; children; cholesterol; circumference; clinical; conclusion; control; control group; correlation; criteria; crp; data; day; decrease; development; diabetes; diabetes mellitus; diet; disease; dm patients; effect; expression; factors; fasting; fat; females; gene; glucose; glucose levels; glucose tolerance; group; hba1c; hdl; health; homa; hypertension; increase; index; individuals; insulin; insulin levels; insulin resistance; insulin sensitivity; intake; leptin; levels; lipid; liver; low; markers; mass; mean; metabolic; methods; mets; mice; mmol; model; months; n =; non; normal; obese; obesity; objective; overweight; oxidative; p =; parameters; participants; patients; plasma; plasma glucose; population; pressure; prevalence; profile; protein; r =; rate; ratio; rats; reduction; results; risk; risk factors; role; sensitivity; serum; stress; study; study group; subjects; syndrome; test; time; tissue; total; treatment; triglycerides; type; university; values; vs.; waist; weeks; weight; women; years
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        item: #34 of 59
          id: cord-034746-uxhpufnv
      author: Nusshag, Christian
       title: Glomerular filtration barrier dysfunction in a self-limiting, RNA virus-induced glomerulopathy resembles findings in idiopathic nephrotic syndromes
        date: 2020-11-05
       words: 3655
      flesch: 29
     summary: Interestingly, the start of normalization of urinary nephrin and PCR levels preceded the first decline of SCr by 48-72 h. Furthermore, in patients with an available urine sample at the time of PCR normalization, the normalization of urinary nephrin levels tended to precede the normalization of PCR levels. In contrast to INS, proteinuria recovered autonomously in hantavirus patients.
    keywords: hantavirus; igg; infection; levels; nephrin; patients; pcr; proteinuria; urinary
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        item: #35 of 59
          id: cord-035308-996ysogr
      author: Twining, Peter
       title: Developing a quality curriculum in a technological era
        date: 2020-11-11
       words: 9388
      flesch: 41
     summary: The consequence of misalignment between curriculum purposes and curriculum practices can be seen in Donaldson's (2015) report on the National Curriculum in Wales. This contrasts with traditional school curricula which tend to compartmentalise 'content' into discrete subjects that are often taught in isolation.
    keywords: assessment; curriculum; development; digital; e.g.; education; knowledge; learning; level; national; new; practice; professional; school; schooling; teachers
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        item: #36 of 59
          id: cord-102738-e5zojanb
      author: Lieberoth, Andreas
       title: Getting Humans to do Quantum Optimization - User Acquisition, Engagement and Early Results from the Citizen Cyberscience Game Quantum Moves
        date: 2015-06-26
       words: 11192
      flesch: 48
     summary: This is the premise of human-computer hybrid optimization: Helping AIs learn through real people's blooming buzzing mess of solutions, when problems can be represented as engaging game levels. In the end, we accept that the high level of cognitive complexity in Quantum Moves compared to citizen science games that rely on players as simple pattern-hunters or mules carrying data gathering devices into the real world , means that we will lose players at a higher rate due to the difficulty, but we believe that it is a viable strategy to work towards a game that is fun and learnable for everyone: On one hand to capitalize on each player's lifetime network value, and on the other in the hope of helping players hone the three skills central to succeed at the scientific levels, moving them beyond the user contribution threshold.
    keywords: atom; citizen; computer; data; design; game; gameplay; human; levels; motivation; moves; physics; players; quantum; quantum moves; science; score; time; tutorial; user
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        item: #37 of 59
          id: cord-104157-rivaoo73
      author: Noreika, Valdas
       title: Alertness fluctuations during task performance modulate cortical evoked responses to transcranial magnetic stimulation
        date: 2019-06-28
       words: 10471
      flesch: 43
     summary: ERP dynamics were additionally studied using data-driven spatiotemporal clustering analyses similar to what we have described previously (Chennu et al., 2013) . In these cases, EEG alpha effects are typically evident only within a relatively short pre-stimulus time period of a few hundred milliseconds (Romei et al., 2008) , and are restricted to sensory or fronto-parietal regions (Capotosto et al., 2009; van Dijk et al., 2008) .
    keywords: alertness; amplitude; data; drowsy; eeg; et al; hori; level; mep; motor; participants; peak; pulse; sleep; stimulation; tep; time; tms; trials
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        item: #38 of 59
          id: cord-121777-3zrnz9nc
      author: Qian, Xuelin
       title: M3Lung-Sys: A Deep Learning System for Multi-Class Lung Pneumonia Screening from CT Imaging
        date: 2020-10-07
       words: 7585
      flesch: 44
     summary: Besides, patient-level classification network only has four layers, and takes a volume of CT slice features, instead of images as input, which are extracted by the former network, to output the patient-level labels (in Section III-C). Then, to recover the temporal information in CT sequence slices and enable CT volumes screening, we propose a patientlevel classification network, taking as input a volume of CT slice features extracted from the slice-level classification network.
    keywords: classification; covid-19; diagnosis; feature; learning; level; lung; multi; network; patient; pneumonia; slice; system
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        item: #39 of 59
          id: cord-149748-ucsxbzen
      author: Borowski, Elisa
       title: Disparities in ridesourcing demand for mobility resilience: A multilevel analysis of neighborhood effects in Chicago, Illinois
        date: 2020-10-29
       words: 8853
      flesch: 39
     summary: Specifically, our results show larger increases in transit disruption responsive ridesourcing during weekdays, nonholidays, and more severe disruptions, as well as in community areas that have higher percentages of White residents and transit commuters, and on the more affluent northside of the city. Our awareness of existing disparities in mobility begs a fundamental question when analyzing the substitution of ridesourcing services during transit disruptions: Is this disruption recovery equitable; that is, are under-resourced transit riders benefitting from ridesourcing-based mobility resilience on par with other travelers?
    keywords: area; chicago; community; demand; disruptions; effects; level; mobility; model; riders; ridesourcing; station; transit; transportation
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        item: #40 of 59
          id: cord-252343-a85wz2hs
      author: Skoda, Eva-Maria
       title: Psychological burden of healthcare professionals in Germany during the acute phase of the COVID-19 pandemic: differences and similarities in the international context
        date: 2020-08-07
       words: 2923
      flesch: 47
     summary: High psychological burden of front-line workers could be found in China 4-6,26 and other countries (e.g. Tan et al . 3 ). Subjective levels of information regarding COVID-19 correlated negatively with generalized anxiety levels across all groups.
    keywords: anxiety; burden; covid-19; hps; information; levels
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        item: #41 of 59
          id: cord-254646-psolkrom
      author: Matsui, Mary S.
       title: Vitamin D Update
        date: 2020-10-14
       words: 5121
      flesch: 38
     summary: The Role of Vitamin D as a Possible Modulator of Susceptibility, Morbidity, and Mortality in SARS-CoV-2 (COVID- 19) That vitamin D should play a role in COVID-19 is not unexpected, since there has been believed to be a link between vitamin D deficiency and respiratory disease for over 100 years. World Health Organization Sunlight and dietary contributions to the seasonal vitamin D status of cohorts of healthy postmenopausal women living at northerly latitudes: a major cause for concern? Vitamin D microencapsulation and fortification: trends and technologies How to get vitamin D from sunlight Sunscreen photoprotection and vitamin D status An important discussion of study protocol variables and their influence on policy Sub-optimal application of a high SPF sunscreen prevents epidermal DNA damage in vivo Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn Kinetics of UV light-induced cyclobutane pyrimidine dimers in human skin in vivo: an immunohistochemical analysis of both epidermis and dermis Children sustain high levels of skin DNA photodamage, with a modest increase of serum 25-hydroxyvitamin D3, after a summer holiday in Northern Europe Global consensus recommendations on prevention and management of nutritional rickets Vitamin D and death by sunshine Protective effects of 1,25 dihydroxyvitamin D3 and its analogs on ultraviolet radiation-induced oxidative stress: a review Photoprotective properties of vitamin D and lumisterol hydroxyderivatives A systematic review of the influence of skin pigmentation on changes in the concentrations of vitamin D and 25-hydroxyvitamin D in plasma/serum following experimental UV irradiation Impact of solar ultraviolet B radiation (290-320 nm) on vitamin D synthesis in children with type IV and V skin Association of serum 25-hydroxyvitamin D with race/ethnicity and constitutive skin color in urban schoolchildren Melanin has a small inhibitory effect on cutaneous vitamin D synthesis: a comparison of extreme phenotypes Vitamin D(3) Supplementation reduces the symptoms of upper respiratory tract infection during winter training in vitamin D-insufficient taekwondo athletes: a randomized controlled trial Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths COVID-19 and vitamin D-is there a link and an opportunity for intervention? Letter: Covid-19, and vitamin D Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: 25(oh)d; deficiency; exposure; health; levels; serum; skin; status; study; sun; vitamin
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        item: #42 of 59
          id: cord-255575-640v00jg
      author: Binny, R. N.
       title: Early intervention is the key to success in COVID-19 control
        date: 2020-10-23
       words: 7351
      flesch: 46
     summary: We then allowed for new international cases arriving over these 5 days (e.g. additional non-residents that may have chosen to travel had the border remained open for longer) by seeding an additional Poisson-distributed random number of international cases from 20 March to 24 March, with an average daily number of seeded cases equal to the actual average daily number of international cases arriving during the week prior to 19 March (33 international cases per day). For scenarios 0, 1, 2, 3 and 6, the model was seeded with the same number of international cases as were actually reported.
    keywords: al4; alert; border; cases; covid-19; level; new; restrictions; scenario
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        item: #43 of 59
          id: cord-264427-frrq4h39
      author: Huang, Ling
       title: The silver lining of COVID‐19: estimation of short‐term health impacts due to lockdown in the Yangtze River Delta region, China
        date: 2020-07-07
       words: 3651
      flesch: 41
     summary: On the other hand, high premature mortality for cities like Bozhou and Suqian in Anhui province (for example, each is ranked 3 rd and 7 th during Level Ⅱ period in 2020 in terms of premature mortality) is more associated with the high PM2.5 concentrations, which is ranked 3 rd and 7 th in terms of average PM2.5 concentration and only 13 rd and 19 th in terms of population. It is well known that poor air quality, with PM2.5 (particulate matters with aerodynamic diameters less than 2.5 μm) being a key criteria pollutant, could have adverse health impacts (Boldo et al., 2011; Cao et al., 2012; Song et al., 2017) and lead to premature mortality (Fang et al., 2016; Liu et al., 2016; Lu et al., 2015b ).
    keywords: health; level; lockdown; mortality; pm2.5; region; yrd
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        item: #44 of 59
          id: cord-264749-m1awr1rm
      author: Saad, Julian M.
       title: A philosophy of health: life as reality, health as a universal value
        date: 2020-03-18
       words: 9762
      flesch: 35
     summary: This shift in values prioritized new variations in population health behavior by: (1) requiring a health warning on cigarette packages; (2) banning cigarette advertising in the broadcasting media; and (3) calling for an annual report on the health consequences of smoking (CDC, 2018) . However, with chronic diseases being responsible for the majority of all cause deaths and being strongly linked to health behavior and lifestyle; predominantly biological views are becoming increasingly insufficient when discussing this health crisis.
    keywords: behavior; cells; e.g.; ease; functioning; functions; health; level; philosophy; population; precision; self; society; system; variation
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        item: #45 of 59
          id: cord-266034-811lov8f
      author: Benameur, Karima
       title: Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020
        date: 2020-09-17
       words: 2456
      flesch: 35
     summary: When we compared historical and present control subjects who had normal cognition (no viral illness) (13), we found that patients with COVID-19 and neurologic symptoms had increased CSF levels of IL-6, IL-8, IL-10, IP-10, and TNF-α ( Figure 2 , panel C). We analyzed CSF inflammatory proteins (Milli-poreSigma, https://www.emdmillipore.com) by using a Luminex-200 platform and a modified manufacturer's protocol as described (9) .
    keywords: coronavirus; cov-2; csf; disease; igm; levels; patients; sars
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        item: #46 of 59
          id: cord-267237-wbwlfx7q
      author: Gómez-Rial, Jose
       title: Increased Serum Levels of sCD14 and sCD163 Indicate a Preponderant Role for Monocytes in COVID-19 Immunopathology
        date: 2020-09-23
       words: 2592
      flesch: 33
     summary: Pearson's correlation coefficients were used to quantify the association between sCD14 and sCD163 concentration and other lab parameters in non-ICU patients. ng/ml in non-ICU patients.
    keywords: covid-19; icu; levels; monocyte; patients; scd14; scd163
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        item: #47 of 59
          id: cord-270184-bq5p2gs6
      author: Alrubaiee, Gamil Ghaleb
       title: Knowledge, attitudes, anxiety, and preventive behaviours towards COVID-19 among health care providers in Yemen: an online cross-sectional survey
        date: 2020-10-13
       words: 5572
      flesch: 46
     summary: Part (1) the socio-demographic characteristics such as age, sex, occupation, education level, years of working experience, and sources of COVID-19 related knowledge. Interesting, the current study indicated lower anxiety level results compared to other studies that were carried out during the outbreak as reported by Huang and Zhao
    keywords: anxiety; attitude; behaviours; covid-19; hcps; knowledge; level; respondents; study
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        item: #48 of 59
          id: cord-280040-xphxlaat
      author: Rutala, William A.
       title: Disinfection and Sterilization in Health Care Facilities An Overview and Current Issues
        date: 2016-09-30
       words: 8374
      flesch: 29
     summary: Guidelines for environmental infection control in health-care facilities Disinfection and sterilization of prion-contaminated medical instruments, reply to Belay Efficacy of a washer-disinfector in eliminating healthcare-associated pathogens from surgical instruments FDA-cleared sterilants and high level disinfectants with general claims for processing reusable medical and dental devices Disinfection and sterilization in healthcare facilities Guidelines for infection control in dental health-care settings-2003 Disinfection: is it time to reconsider Spaulding? Brief summary of the gastroenterology and urology devices panel meeting Gastrointestinal endoscopes: a need to shift from disinfection to sterilization? ERCP scopes: what can we do to prevent infections? For this reason, several manufacturers have developed room disinfection units that can decontaminate environmental surfaces and objects.
    keywords: care; cleaning; contact; disinfection; health; hld; items; level; pathogens; patient; reprocessing; room; sterilization; surfaces; use
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        item: #49 of 59
          id: cord-284694-bk6bnox0
      author: Wang, Changsong
       title: Cytokine Levels in the Body Fluids of a Patient With COVID-19 and Acute Respiratory Distress Syndrome: A Case Report
        date: 2020-05-12
       words: 560
      flesch: 35
     summary: Interleukin-6 blockers have been used to treat cytokine storm in patients with other causes of cytokine storm (3), and tocilizumab has been suggested for immunotherapy for severe patients with extensive lung lesions and elevated IL-6 levels (3). As a result, we wonder whether tocilizumab would have affected the IL-6 levels we observed and whether it might have improved this patient's disease course, especially because others have reported that as COVID-19 progresses to its middle and late stages, the expression of inflammatory cytokines is related to the severity of the disease (4).
    keywords: covid-19; levels
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        item: #50 of 59
          id: cord-285151-zynor0b2
      author: Eisenhut, Michael
       title: Neopterin in Diagnosis and Monitoring of Infectious Diseases
        date: 2013-12-08
       words: 6009
      flesch: 28
     summary: Successful highly active antiretroviral therapy is associated with a decrease in neopterin levels. Testing of 328 samples of 29 HIV infected individuals found that 44/68 (64.7%) of samples, which were HIV-1 RNA and p24 antigen positive had elevated neopterin levels (>10 nmol/L).
    keywords: csf; hepatitis; hiv; infection; levels; marker; neopterin; patients; serum; treatment; tuberculosis; urinary; virus
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        item: #51 of 59
          id: cord-296717-ay4wcmk3
      author: Long, Wen
       title: Can the Chinese volatility index reflect investor sentiment?
        date: 2020-10-20
       words: 7171
      flesch: 48
     summary: In order to measure the expectation of investor, scholars put forward the concept of investor sentiment index. We use several technologies including data cleaning, text representation, feature extraction and classification, to compute investor sentiment index with individual sentiments, which will be applied into following study.
    keywords: data; factor; index; investor; investor sentiment; ivx; level; market; sentiment; sentiment index; stock; term; volatility
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        item: #52 of 59
          id: cord-312418-e4g5u1nz
      author: Melillo, Alessandro
       title: Rabbit Clinical Pathology
        date: 2007-09-18
       words: 6444
      flesch: 45
     summary: Test dipsticks work well to evaluate blood, glucose, ketone, and pH levels in rabbit urine but are not accurate for other parameters. The pH of rabbit urine tends to be high (7.5 to 9) in rabbits fed a correct diet.
    keywords: blood; calcium; cause; chronic; disease; levels; liver; protein; rabbits; reference; serum; species; stress; urine
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        item: #53 of 59
          id: cord-312580-r57rkrya
      author: Harcourt-Brown, Frances
       title: Chapter 6 Clinical pathology
        date: 2002-12-31
       words: 12630
      flesch: 47
     summary: Automated differential white cells counts cannot be relied upon for rabbit blood and accurate results can only be obtained using manual counting methods (Kabata et al., 1991) . Although basophils are rare in blood films from species such as the dog, they may be seen commonly in rabbit blood (Kerr, 1989) .
    keywords: blood; calcium; cause; cell; concentrations; disease; laboratory; levels; liver; parameters; plasma; potassium; rabbits; range; reference; results; serum; species; total; urine; values; white
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        item: #54 of 59
          id: cord-332432-q7u943k6
      author: Hofkirchner, Wolfgang
       title: A paradigm shift for the Great Bifurcation
        date: 2020-06-30
       words: 7662
      flesch: 40
     summary: It is the world occurrence of the enclosure of commons that is detrimental to sharing the systemic synergy effects and thus to the cohesion of social systems. Philosophy that was deprived of fruitful relations to the disciplines of science in what had become normal science turns into systems philosophy now; formal sciences turn into formal as well as non-formal systems methodology; realworld sciences turn into sciences of real-world systems, that is, material, living or social systems; and, finally, applied sciences turn into a science that makes artefacts by designing systems and, in doing so, integrates them with social systems.
    keywords: actors; evolution; hofkirchner; human; information; level; relations; sciences; social; society; systems; world
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        item: #55 of 59
          id: cord-336201-fl606l3b
      author: Daryabor, Gholamreza
       title: The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System
        date: 2020-07-22
       words: 13880
      flesch: 25
     summary: The endocrine part is made of different cell types, including α, β, δ, and ε cells that secrete glucagon, insulin, somatostatin, and ghrelin hormones, respectively. A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2 Novel clearance mechanisms of platelets Flow cytometric analysis of platelets type 2 diabetes mellitus reveals 'angry' platelets Platelet activity and hypercoagulation in type 2 diabetes Increased circulating resistin is associated with insulin resistance, oxidative stress and platelet activation in type 2 diabetes mellitus Increased levels of soluble adhesion molecules in type 2 (non-insulin dependent) diabetes mellitus are independent of glycaemic control Molecular mechanisms underpinning microparticle-mediated cellular injury in cardiovascular complications associated with diabetes Association between mean platelet volume in the pathogenesis of type 2 diabetes mellitus and diabetic macrovascular complications in Japanese patients Increased erythrocyte-and platelet-derived microvesicles in newly diagnosed type 2 diabetes mellitus Type 2 diabetes and cardiovascular disease: have all risk factors the same strength? Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36 Central role of the P2Y12 receptor in platelet activation Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model Introduction to the human gut microbiota Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection Faecalibacterium prausnitzii-derived microbial anti-inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression Considering gut microbiota in treatment of type 2 diabetes mellitus Metformin effect on gut microbiota: insights for HIV-related inflammation The bacterium Akkermansia muciniphila: a sentinel for gut permeability and its relevance to HIV-related inflammation High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells The role of iron in diabetes and its complications Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCalpha-dependent manner Betacell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Fatty acid-induced lipotoxicity in pancreatic beta-cells during development of type 2 diabetes Mesenchymal stem cell therapy in type 2 diabetes mellitus Establishment of insulin-producing cells from human embryonic stem cells underhypoxic condition for cell based therapy Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction A simple method for the generation of insulin producing cells from bone marrow mesenchymal stem cells Secretagogin affects insulin secretion in pancreatic beta-cells by regulating actin dynamics and focal adhesion Secretagogin regulates insulin signaling by direct insulin binding.
    keywords: cells; diabetes; diabetes mellitus; disease; dm patients; dysfunction; endothelial; et al; expression; glucose; human; immune; individuals; infections; inflammation; insulin; levels; macrophages; mellitus; mice; patients; resistance; risk; role; t2 dm; type
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        item: #56 of 59
          id: cord-344656-xx76w7c0
      author: Sarder, MD
       title: Logistics customer services
        date: 2020-10-16
       words: 6684
      flesch: 46
     summary: key: cord-344656-xx76w7c0 authors: Sarder, MD title: Logistics customer services date: 2020-10-16 journal: Logistics Transportation Systems DOI: 10.1016/b978-0-12-815974-3.00008-3 sha: doc_id: 344656 cord_uid: xx76w7c0 This chapter discusses customer service in logistics in terms of different elements, the relative importance of those elements, and how these elements impact the effectiveness of logistics operations. The process includes the receipt of the order, managing the payment, picking and packing the goods, shipping the package, delivering the package, providing customer service for the end-user, and handling the possible return of the goods.
    keywords: business; customer; customer service; delivery; level; logistics; order; product; quality; sales; service; time
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        item: #57 of 59
          id: cord-349581-o320ogmg
      author: Robertson, Lindsay J.
       title: The technological 'exposure' of populations; characterisation and future reduction
        date: 2020-05-25
       words: 9157
      flesch: 31
     summary: Nevertheless, hazards that affect various populations certainly exist, and a short list will serve to illustrate the significance of evaluating population exposure levels. In many cases the centralisation that causes high exposure levels for the production of complex substances, has resulted primarily from available economies of scale, and only secondarily from the substances' complexity.
    keywords: data; exposure; goods; individual; information; j o; level; metric; population; population exposure; r n; services; storage; system; u r; vulnerability
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        item: #58 of 59
          id: cord-349831-0u9y35qo
      author: Ellis, George F. R.
       title: The Causal Closure of Physics in Real World Contexts
        date: 2020-08-18
       words: 15767
      flesch: 57
     summary: The associated set of biological levels, taking the underlying physics for granted, is the set of levels L4-L5. The associated set of biological levels, taking the underlying physics for granted, is the set of levels L4-L7.
    keywords: biology; case; causal; causation; closure; emergence; engineering; example; level; life; networks; physics; properties; sect; set; system; theory; time; way
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        item: #59 of 59
          id: cord-352687-gncmygda
      author: Science, Michelle
       title: Low Serum 25-Hydroxyvitamin D Level and Risk of Upper Respiratory Tract Infection in Children and Adolescents
        date: 2013-05-15
       words: 3022
      flesch: 42
     summary: Vitamin D levels were analyzed as both a continuous variable (log-transformed to correct positive skew) and dichotomized based on both the American Academy of Pediatrics (AAP [≥50 nmol/L]) Although differences in vitamin D levels were not found in these studies, a higher proportion of participants with acute lower respiratory infection were found to have vitamin D receptor polymorphisms associated with reduced receptor expression in one study [34] .
    keywords: 25(oh)d; children; infection; levels; serum; vitamin
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