# bib

id: cord-304718-w469n0o8
author: Wang, Yan
title: Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection
date: 2009-05-01
extension: .txt
mime: text/plain
words: 2600
sentence: 123
flesch: 46
cache: cache/cord-304718-w469n0o8.txt
txt: txt/cord-304718-w469n0o8.txt
summary:
  To examine the hypothesis that polymorphisms of the MASP2 gene in SARS patients are genetic factors that influence infection susceptibility, we studied MASP2 gene polymorphisms in DNA from two groups of Chinese SARS patients, and compared these with normal blood donors from the same region. Our data do not suggest a role for MASP2 polymorphisms in SARS susceptibility in northern and southern China.


id: cord-007375-hqmyund4
author: Tang, Yi-Wei
title: Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine
date: 2007-10-01
extension: .txt
mime: text/plain
words: 2620
sentence: 93
flesch: 36
cache: cache/cord-007375-hqmyund4.txt
txt: txt/cord-007375-hqmyund4.txt
summary:
  When poor and normal responses were combined, the -1082 A allele in the IL-10 promoter conferred a significantly decreased risk of the development of adverse responses (P = .041). In comparison to the poor/normal response group, the GrA polymorphism in the IL-10 promoter Ϫ1082 allele indicated a significantly decreased risk for the development of adverse responses (OR, 0.558


id: cord-292581-6ipzvryb
author: Alagarasu, Kalichamy
title: Elevated levels of vitamin D and deficiency of mannose binding lectin in dengue hemorrhagic fever
date: 2012-05-04
extension: .txt
mime: text/plain
words: 3747
sentence: 172
flesch: 47
cache: cache/cord-292581-6ipzvryb.txt
txt: txt/cord-292581-6ipzvryb.txt
summary:
  Although MBL levels were not different DF and DHF cases based on immune status, the percentage of primary DHF cases (50%) having MBL levels lower than 500 ng/ml were less compared to primary DF cases (P = 0.038). Vitamin D concentrations were not significantly different between primary DF and primary DHF cases (P > 0.050).


id: cord-000524-5y9kfyk9
author: Ling, Man To
date: 2011-11-11
extension: .txt
mime: text/plain
words: 4395
sentence: 174
flesch: 42
cache: cache/cord-000524-5y9kfyk9.txt
txt: txt/cord-000524-5y9kfyk9.txt
title:
  Mannose-Binding Lectin Contributes to Deleterious Inflammatory Response in Pandemic H1N1 and Avian H9N2 Infection

summary:
  Pandemic (H1N1) 2009dbriefing note 23 Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003 Human infection with influenza H9N2 H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China Phylogenetic perspectives in innate immunity The mannosebinding lectin: a prototypic pattern recognition molecule A second serine protease associated with mannan-binding lectin that activates complement The human mannose-binding protein functions as an opsonin Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series Human mannose-binding protein functions as an opsonin for influenza A viruses Complementdependent neutralization of influenza virus by a serum mannosebinding lectin Human mannan-binding lectin inhibits the infection of influenza A virus without complement Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies Defense against influenza A virus infection: essential role of the chemokine system Julkunen I. TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitidis serogroup B Mannose-binding lectin recognizes peptidoglycan via the N-acetyl glucosamine moiety, and inhibits ligand-induced proinflammatory effect and promotes chemokine production by macrophages Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection Influenza virus directly infects human natural killer cells and induces cell apoptosis Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian influenza viruses Inhibition of human natural killer cell activity by influenza virions and hemagglutinin Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus P58(IPK): a novel ''CIHD'' member of the host innate defense response against pathogenic virus infection The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a {gamma}{delta} T cell population in humanized mice Mannose-binding proteins in human serum: identification of mannose-specific immunoglobulins and a calcium-dependent lectin, of broader carbohydrate specificity, secreted by hepatocytes Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice Role of interleukin-1 in infectious diseases Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection Inflammasomes as mediators of immunity against influenza virus Biologic basis for interleukin-1 in disease Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice Inflammatory responses in influenza A virus infection Shock and tissue injury induced by recombinant human cachectin Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia Clinical aspects and cytokine response in severe H1N1 influenza A virus infection Molecular pathogenesis of influenza A virus infection and virusinduced regulation of cytokine gene expression Local and systemic cytokine responses during experimental human influenza A virus infection. Both strains of influenza virus could successfully infect MBL WT and MBL KO mice as evidenced by the significant weight loss in these mice after virus infection.


id: cord-282433-p6jl9gxf
author: Tu, Xinyi
date: 2015-03-27
extension: .txt
mime: text/plain
words: 4620
sentence: 144
flesch: 35
cache: cache/cord-282433-p6jl9gxf.txt
txt: txt/cord-282433-p6jl9gxf.txt
title:
  Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection

summary:
  9 SARS-associated coronavirus Pathogenesis of severe acute respiratory syndrome Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection The association of RANTES polymorphism with severe acute respiratory syndrome in Hong Kong and Beijing Chinese Association between mannose-binding lectin gene polymorphisms and susceptibility to severe acute respiratory syndrome coronavirus infection Genetic variation of the human alpha-2-Heremans-Schmid glycoprotein (AHSG) gene associated with the risk of SARS-CoV infection Genetic susceptibility to infectious disease: Therefore, although the highly significant associations between CCL2 G-2518A and susceptibility to SARS-CoV infection were biologically plausible, and strengthened by our 4 independent caseecontrol studies, it remains interesting to investigate that whether there exist population-specific differences for this polymorphism to SARS susceptibility between Chinese and Europeans.


id: cord-256769-flfycl7i
author: Stoermer, Kristina A.
title: Complement and Viral Pathogenesis
date: 2011-03-01
extension: .txt
mime: text/plain
words: 10374
sentence: 321
flesch: 28
cache: cache/cord-256769-flfycl7i.txt
txt: txt/cord-256769-flfycl7i.txt
summary:
  The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization Autophagy induction by the pathogen receptor CD46 Decreased function of peripheral blood dendritic cells in patients with hepatocellular carcinoma with hepatitis B and C virus infection A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection Murine gammaherpesvirus 68 encodes a functional regulator of complement activation Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection T-cell regulation: with complements from innate immunity Activation of human CD4 + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype Properdin: emerging roles of a patternrecognition molecule Complement C5a receptor is essential for the optimal generation of antiviral CD8 + T cell responses Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection Mechanism of complement inactivation by glycoprotein C of herpes simplex virus Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1 Global spread and persistence of dengue Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma Suppression of host immune response by the core protein of hepatitis C virus: possible implications for hepatitis C virus persistence Angiotensinconverting enzyme 2 is a functional receptor for the SARS coronavirus Seizures following picornavirus infection Role for complement in the development of seizures following acute viral infection High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever Structure and regulatory profile of the monkeypox inhibitor of complement: comparison to homologs in vaccinia and variola and evidence for dimer formation Cutting edge: murine CD59a modulates antiviral CD4 + T cell activity in a complementindependent manner Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo In vivo role of complement-interacting domains of herpes simplex virus type 1 glycoprotein gC Herpes simplex virus type 1 evades the effects of antibody and complement in vivo Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein Nonenveloped nucleocapsids of hepatitis C virus in the serum of infected patients Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation Complement and coagulation: strangers or partners in crime? Modulation of the antitumor immune response by complement Abrogation of the alternative complement pathway by targeted deletion of murine factor B Protective immune responses against West Nile virus are primed by distinct complement activation pathways Complement activation is required for induction of a protective antibody response against West Nile virus infection Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus Hepatitis C virus and the lung: implications for therapy Induction of p38-and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced disease Complement receptor 3 promotes severe ross river virus-induced disease Surviving mousepox infection requires the complement system Ectromelia virus inhibitor of complement enzymes protects intracellular mature virus and infected cells from mouse complement Enhancement of neutralizing activity of influenza virus-specific antibodies by serum components Kaposi's sarcomaassociated herpesvirus (human herpesvirus 8) open reading frame 4 protein (kaposica) is a functional homolog of complement control proteins Herpes and pox viral complement control proteins: 'the mask of self Alternative complement pathway deregulation is correlated with dengue severity Natural antibodies and complement link innate and acquired immunity Control of early viral and bacterial distribution and disease by natural antibodies Protective T cell-independent antiviral antibody responses are dependent on complement Complement: a key system for immune surveillance and homeostasis Variola virus immune evasion design: expression of a highly efficient inhibitor of human complement Interaction of vaccinia virus complement control protein with human complement proteins: factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1 Interaction of mannose-binding lectin with primary isolates of human immunodeficiency virus type 1 Non-enveloped HCV core protein as constitutive antigen of cold-precipitable immune complexes in type II mixed cryoglobulinaemia Role of the receptor for the globular domain of C1q protein in the pathogenesis of hepatitis C virus-related cryoglobulin vascular damage Host cell-derived complement control proteins CD55 and CD59 are incorporated into the virions of two unrelated enveloped viruses. Gammaherpesviruses, including Kaposi's sarcoma-associated herpesvirus, herpesvirus saimiri, and murine γ-herpesvirus 68 (γHV68) encode homologs of complement regulatory proteins (Albrecht and Fleckenstein, 1992; Mullick et al., 2003a; Spiller et al., 2003; Virgin et al., 1997) .


id: cord-017438-x12d2ewc
author: Gupta, Anita
title: MBL Deficiency as Risk of Infection and Autoimmunity
date: 2012-03-20
extension: .txt
mime: text/plain
words: 15416
sentence: 577
flesch: 37
cache: cache/cord-017438-x12d2ewc.txt
txt: txt/cord-017438-x12d2ewc.txt
summary:
  On the other hand, MBL levels were low (0.30 ng/mL) in women with recurrent vulvovaginal candidiasis and were associated with a high gene mutation frequency compared to controls (1.28 ng/mL) While addressing possible correlation between MBL levels and clinical conditions an issue is how to define MBL deficiency.


id: cord-278644-u4swxsjj
author: Degn, Søren E.
title: MAp19, the alternative splice product of the MASP2 gene
date: 2011-10-28
extension: .txt
mime: text/plain
words: 8683
sentence: 336
flesch: 53
cache: cache/cord-278644-u4swxsjj.txt
txt: txt/cord-278644-u4swxsjj.txt
summary:
  MAp19 is relatively well conserved, the amino acid sequence for human MAp19 being 80% and 77% identical with mouse and rat MAp19, respectively, and the unique 4 C-terminal amino acids are conserved between these species (Fig. 1A) . Two monoclonal rat antibodies, 6G12 (isotype IgG1), reacting with the common part of human MAp19 and MASP-2 (Fig. 1D) , and 8B5 (IgG1), specific for MASP-2, were previously generated (Møller-Kristensen et al., 2003) .


id: cord-023443-pvz7dll9
title: Abstracts for the Scandinavian Society for Immunology 35th Annual Meeting and 20th Summer School
date: 2004-06-02
extension: .txt
mime: text/plain
words: 16664
sentence: 757
flesch: 44
cache: cache/cord-023443-pvz7dll9.txt
txt: txt/cord-023443-pvz7dll9.txt
summary:
  Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment. During contact sensitivity reaction, immune cells proliferate.


id: cord-023372-ft8cp9op
author: Rahman, Q. K.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16884
sentence: 767
flesch: 44
cache: cache/cord-023372-ft8cp9op.txt
txt: txt/cord-023372-ft8cp9op.txt
title:
  The Immunomodulatory Effect of Heat Shock Protein 70: Immunization with a DNA Construct Based on the Malarial Antigen Fused with a Fragment of HSP 70 Primes for a Th‐1 Type of Response

summary:
  Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment. During contact sensitivity reaction, immune cells proliferate.


id: cord-023389-ilrp8vb7
author: Wefer, J.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16866
sentence: 766
flesch: 43
cache: cache/cord-023389-ilrp8vb7.txt
txt: txt/cord-023389-ilrp8vb7.txt
title:
  Protective DNA Vaccination Against MOG(91‐108)‐Induced Experimental Autoimmune Encephalomyelitis Involves Induction of IFNβ

summary:
  Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment. During contact sensitivity reaction, immune cells proliferate.


id: cord-023403-jzdrvfvr
author: Ahlfors, E.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16946
sentence: 773
flesch: 44
cache: cache/cord-023403-jzdrvfvr.txt
txt: txt/cord-023403-jzdrvfvr.txt
title:
  Proliferation of Cells in the Oral Mucosa, the Ear Skin and the Regional Lymph Nodes in Mice Sensitized and Elicited with a Hapten

summary:
  Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment. Scand J Immunol DOI: 10.1111/j.0300-9475.2004.01423ac.x sha: doc_id: 23403 cord_uid: jzdrvfvr During contact sensitivity reaction, immune cells proliferate.


id: cord-023414-xxw5kptr
author: Chistensen, H. R.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16935
sentence: 771
flesch: 44
cache: cache/cord-023414-xxw5kptr.txt
txt: txt/cord-023414-xxw5kptr.txt
title:
  Characterization of a Large Panel of Lactic Acid Bacteria Derived from the Human Gut for their Capacity to Polarize Dendritic Cell

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023374-87ob1exq
author: Sukhija, S.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16911
sentence: 767
flesch: 44
cache: cache/cord-023374-87ob1exq.txt
txt: txt/cord-023374-87ob1exq.txt
title:
  Levels, Complement Activity and Polymorphisms of Mannan‐Binding Lectin in Patients of Bronchial Asthma with Allergic Rhinitis

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023391-bq5w3jk9
author: Utermöhlen, O.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16877
sentence: 765
flesch: 44
cache: cache/cord-023391-bq5w3jk9.txt
txt: txt/cord-023391-bq5w3jk9.txt
title:
  Delayed Elimination of the LCM Virus from Acid Sphingomyelinase‐Deficient Mice due to Reduced Expansion of Virus‐Specific CD8(+) T Lymphocytes

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023445-c4tqioz1
author: Lauridsen, C.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16968
sentence: 771
flesch: 44
cache: cache/cord-023445-c4tqioz1.txt
txt: txt/cord-023445-c4tqioz1.txt
title:
  Supplementation of Vitamin C to Weaner Diets Increases IgM Concentration and Improves the Biological Activity of Vitamin E in Alveolar Macrophages

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023415-hhvmsn5b
author: Karlsson, H.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16930
sentence: 768
flesch: 43
cache: cache/cord-023415-hhvmsn5b.txt
txt: txt/cord-023415-hhvmsn5b.txt
title:
  Pattern of Cytokine Responses to Gram‐Positive and Gram‐Negative Commensal Bacteria is Profoundly Changed when Monocytes Differentiate into Dendritic Cells

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023375-x4p187u7
author: Alitalo, A.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 17080
sentence: 770
flesch: 44
cache: cache/cord-023375-x4p187u7.txt
txt: txt/cord-023375-x4p187u7.txt
title:
  Lysine‐Dependent Binding of OspE to the C‐terminus of Factor H Mediates Complement Resistance in Borrelia burgdorferi

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023417-by18aczt
author: Vilhelmsson, M.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16952
sentence: 769
flesch: 44
cache: cache/cord-023417-by18aczt.txt
txt: txt/cord-023417-by18aczt.txt
title:
  The Malassezia sympodialis Allergen Mala s 11 with Sequence Similarity to Manganese Superoxide Dismutase Induces Maturation and Production of Inflammatory Cytokines in Human Dendritic Cells

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023438-g0k0vvdc
author: Krog, J.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16901
sentence: 768
flesch: 44
cache: cache/cord-023438-g0k0vvdc.txt
txt: txt/cord-023438-g0k0vvdc.txt
title:
  The Effects of Hyperbaric Exposure on Human Peripheral Blood Mononuclear Cells, with Special Emphasis on Natural Killer Cell Cytotoxicity and Subsets

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023394-ptfjxpo6
author: Isa, A.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16925
sentence: 768
flesch: 44
cache: cache/cord-023394-ptfjxpo6.txt
txt: txt/cord-023394-ptfjxpo6.txt
title:
  Mapping of the Ex Vivo Cellular Immune Response Against the Complete Human Parvovirus B19 Genome During Acute Infection

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023439-r04y1j22
author: Hedegaard, C. J.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16953
sentence: 767
flesch: 44
cache: cache/cord-023439-r04y1j22.txt
txt: txt/cord-023439-r04y1j22.txt
title:
  The Role of Immune Complexes Consisting of Myelin Basic Protein (MBP), Anti‐MBP Antibodies and Complement in Promoting CD4(+) T‐cell Responses to MBP in Health and Multiple Sclerosis

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023402-8qfmo6rq
author: Reinholdt, J.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 17031
sentence: 776
flesch: 43
cache: cache/cord-023402-8qfmo6rq.txt
txt: txt/cord-023402-8qfmo6rq.txt
title:
  Pneumococcal IgA1 Protease Activity Interferes with Opsonophagocytosis of Streptococcus Pneumoniae Mediated by Serotype‐Specific Human Monoclonal IgA1 Antibodies

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023373-6wh1kb3p
author: Melchjorsen, J.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16861
sentence: 766
flesch: 44
cache: cache/cord-023373-6wh1kb3p.txt
txt: txt/cord-023373-6wh1kb3p.txt
title:
  Differential Requirements for Toll‐Like Receptor Signalling for Induction of Chemokine Expression by Herpes Simplex Virus and Sendai Virus

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023407-s85g7g0x
author: Huang, Y.‐M.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 17096
sentence: 774
flesch: 44
cache: cache/cord-023407-s85g7g0x.txt
txt: txt/cord-023407-s85g7g0x.txt
title:
  Anti‐Inflammatory Liver X Receptors and Related Molecules in Multiple Sclerosis Patients from Sardinia and Sweden

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-304626-ffao7vka
author: Mellors, Jack
title: Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
date: 2020-07-09
extension: .txt
mime: text/plain
words: 11774
sentence: 333
flesch: 21
cache: cache/cord-304626-ffao7vka.txt
txt: txt/cord-304626-ffao7vka.txt
summary:
  Activated C1s cleaves complement proteins C4 and C2 into active fragments C4b and C2a, along with an inactive fragment (C2b), and a proteaseactivated receptor (PAR)1/PAR4 ligand (C4a) which increases endothelial cell permeability (26). Dyn Immune Activ Viral Dis Mechanism for complement-mediated, antibody-dependent enhancement of human immunodeficiency virus type 1 infection in MT2 cells is enhanced entry through CD4, CD21, and CXCR4 chemokine receptors Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody Antibody-dependent enhancement of Ebola virus infection Complement C3 plays a key role in inducing humoral and cellular immune responses to influenza virus strain-specific hemagglutinin-based or crossprotective M2 extracellular domain-based vaccination Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination GP38-targeting monoclonal antibodies protect adult mice against lethal Crimean-Congo hemorrhagic fever virus infection Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development Complement activation is required for induction of a protective antibody response against West Nile virus infection C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile Virus C1q inhibits antibody-dependent enhancement of flavivirus infection in vitro and in vivo in an IgG subclass specific manner Complement-mediated virus infectivity neutralisation by HLA antibodies is associated with sterilising immunity to SIV challenge in the Macaque Model for HIV/AIDS C3d of complement as a molecular adjuvant: bridging innate and acquired immunity Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant Novel function of complement C3d as an autologous helper T-cell target C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells Construction and immunogenicity of DNA vaccines encoding fusion protein of murine complement C3d-p28 and GP5 gene of porcine reproductive and respiratory syndrome virus Fusion of C3d molecule with neutralization epitope(s) of hepatitis E virus enhances antibody avidity maturation and neutralizing activity following DNA immunization Enhancement of antibodies to the human immunodeficiency virus type 1 envelope by using the molecular adjuvant C3d Immune effect of Newcastle Disease Virus DNA vaccine with C3d as a molecular adjuvant Protection against influenza virus infection by intranasal administration of C3d-fused hemagglutinin Complement, interferon and lupus Complement component 3 regulates IFN-α production by plasmacytoid dendritic cells following TLR7 activation by a plant Virus-like nanoparticle Complement-mediated regulation of metabolism and basic cellular processes Complement in the brain Interaction between the coagulation and complement system Evolution of the complement system: from defense of the single cell to guardian of the intravascular space Sea urchin coelomocytes specifically express a homologue of the complement component C3 The role of complement in Cnidarian-Dinoflagellate symbiosis and immune challenge in the sea Anemone Aiptasia pallida Specific alterations in complement protein activity of little brown myotis (Myotis lucifugus) hibernating in white-nose syndrome affected sites The complement in milk and defense of the bovine mammary gland against infections Complement-mediated killing of Borrelia garinii-bactericidal activity of wild deer serum Genetic association of the Porcine C9 complement component with hemolytic complement activity Inhibition of the alternative pathway of nonhuman infant complement by Porin B2 contributes to virulence of Neisseria meningitidis in the Infant Rat Model


id: cord-266739-oay8gbit
author: Eisen, Damon P.
date: 2011-11-30
extension: .txt
mime: text/plain
words: 2848
sentence: 104
flesch: 39
cache: cache/cord-266739-oay8gbit.txt
txt: txt/cord-266739-oay8gbit.txt
title:
  No association between mannose-binding lectin deficiency and H1N1 2009 infection observed during the first season of this novel pandemic influenza virus

summary:
  MBL2 genotype was not determined in this study because we have previously demonstrated that MBL level is a more sensitive and specific marker of MBL deficiency because a considerable number of individuals bear wild-type MBL2 with unmeasureable MBL Comparison of the nonnormally distributed results for MBL level and function was performed using Mann-Whitney tests and frequency of MBL deficiency was compared using 2 tests.


id: cord-311913-cplhq4k9
author: SATO, Satoshi
title: Association of mannose‐binding lectin gene polymorphisms with Kawasaki disease in the Japanese
date: 2009-11-23
extension: .txt
mime: text/plain
words: 2311
sentence: 105
flesch: 48
cache: cache/cord-311913-cplhq4k9.txt
txt: txt/cord-311913-cplhq4k9.txt
summary:
  Differences in MBL genotype frequencies among KD patients and healthy controls were determined using Fisher's exact test. The MBL genotype distributions between KD patients and controls indicated high frequencies of XA/O and XA/XA types (P = 0.028, OR 2.743, 95% CI 1.069-7.035).


id: cord-310110-haukpwtf
author: Guo, Jinlei
date: 2015-02-27
extension: .txt
mime: text/plain
words: 3454
sentence: 118
flesch: 42
cache: cache/cord-310110-haukpwtf.txt
txt: txt/cord-310110-haukpwtf.txt
title:
  Limited effect of recombinant human mannose-binding lectin on the infection of novel influenza A (H7N9) virus in vitro

summary:
  Previous studies showed that MBL can bind to a range of clinically relevant microorganisms such as Staphylococcus aureus, Candida Albicans [2] , HIV, SARS-CoV, Ebola virus, HSV, influenza virus For HI reverse assay: rhMBL was diluted in HBSS containing 10 mM EDTA or 10 mg/mL mannan, then incubated with 4 HAU of influenza virus.


id: cord-324840-ug5a9wx6
author: De Pascale, Gennaro
title: The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock
date: 2013-10-02
extension: .txt
mime: text/plain
words: 5197
sentence: 188
flesch: 30
cache: cache/cord-324840-ug5a9wx6.txt
txt: txt/cord-324840-ug5a9wx6.txt
summary:
  The results indicated that lower MBL levels during fetal inflammatory response syndrome (FIRS) were associated with higher risk of sepsis development independently from gestational age and birth weight Compared with healthy subjects, MBL deficient patients were at increased risk of sepsis, with a significant higher mortality rate in presence of levels below 1000 ng/mL (47.2% versus 22.2%, = 0.05).


id: cord-268902-npug5c8p
author: Liu, Yang
title: The Roles of Direct Recognition by Animal Lectins in Antiviral Immunity and Viral Pathogenesis
date: 2015-01-29
extension: .txt
mime: text/plain
words: 6966
sentence: 264
flesch: 32
cache: cache/cord-268902-npug5c8p.txt
txt: txt/cord-268902-npug5c8p.txt
summary:
  Such lectin-based antiviral strategies are divided into two parts: (1) lectin-based immune activation and (2) blockade of lectin receptors against viral entry [129] . Differential glycosylation patterns of viral surface proteins strongly influence the efficiency of viral recognition by DC-SIGN/L-SIGN [59, 60] .


id: cord-342176-tewfm8it
author: Kjærup, Rikke M.
date: 2013-11-08
extension: .txt
mime: text/plain
words: 8402
sentence: 322
flesch: 53
cache: cache/cord-342176-tewfm8it.txt
txt: txt/cord-342176-tewfm8it.txt
title:
  Adjuvant effects of mannose-binding lectin ligands on the immune response to infectious bronchitis vaccine in chickens with high or low serum mannose-binding lectin concentrations

summary:
  Purified chicken MBL was bought from the Department of Cancer and Inflammation Research, University of Southern Denmark. The addition of MBL ligands to the IBV vaccine, especially FOS, enhanced the production of IBV-specific IgG antibody production in L10H chickens, but not L10L chickens after the second vaccination.


id: cord-306111-wn1gxhk9
author: Dommett, R. M.
title: Mannose‐binding lectin in innate immunity: past, present and future
date: 2006-09-01
extension: .txt
mime: text/plain
words: 9072
sentence: 296
flesch: 33
cache: cache/cord-306111-wn1gxhk9.txt
txt: txt/cord-306111-wn1gxhk9.txt
summary:
  Therapeutic potential of MBL MBL replacement was first attempted (without any knowledge of the deficiency) when fresh frozen plasma was given to patients and found to correct the opsonic defect (28, 29) . The mannose-binding protein A but not C is an acute phase reactant Structure of a C-type mannose-binding protein complexed with an oligosaccharide Human mannose-binding protein is identical to a component of Ra-reactive factor Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series Cutting edge: complementactivating complex of ficolin and mannose-binding lectin-associated serine protease Mannose-binding lectin accelerates complement activation and increases serum killing of Neisseria meningitidis serogroup C Activation of the lectin complement pathway by H-ficolin (Hakata antigen) Differential recognition of obligate anaerobic bacteria by human mannose-binding lectin Differential binding of mannose-binding lectin to respiratory pathogens in cystic fibrosis Human mannose-binding protein inhibits infection of HeLa cells by Chlamydia trachomatis Binding of mannan-binding protein to various bacterial pathogens of meningitis Interaction of human mannose-binding protein with Mycobacterium avium Interaction of mannose-binding lectin with primary isolates of human immunodeficiency virus type 1 High mannose glycans and sialic acid on gp120 regulate binding of mannose-binding lectin (MBL) to HIV type 1 Mannose binding lectin (MBL) and HIV Mannan-binding protein and bovine conglutinin mediate enhancement of herpes simplex virus type 2 infection in mice Mannan-binding lectin modulates the response to HSV-2 infection Mannose binding protein is involved in first-line host defence: evidence from transgenic mice Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an agglutinin for acapsular yeast cells Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS Recognition of plasmodium falciparum proteins by mannan-binding lectin, a component of the human innate immune system The major surface glycoprotein of Trypanosoma cruzi amastigotes are ligands of the human serum mannose-binding protein Novel MASP2 variants detected among North African and Sub-Saharan individuals Analysis of mannose-binding lectin 2 (MBL2) genotype and the serum protein levels in the Korean population Association of mannose-binding lectin gene haplotype LXPA and LYPB with interferon-resistant hepatitis C virus infection in Japanese patients


id: cord-023419-lnmc6vv5
author: Steinhauer, C.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16905
sentence: 768
flesch: 43
cache: cache/cord-023419-lnmc6vv5.txt
txt: txt/cord-023419-lnmc6vv5.txt
title:
  High‐Throughput Proteomics on Antibody‐based Microarrays: the Importance of Probe and Surface Design

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023431-zjyrhlxn
author: Sigmundsdóttir, H.
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16888
sentence: 766
flesch: 43
cache: cache/cord-023431-zjyrhlxn.txt
txt: txt/cord-023431-zjyrhlxn.txt
title:
  Differential Effects of Interleukin‐12 and Interleukin‐10 on Superantigen‐Induced Expression of Cutaneous Lymphocyte‐Associated Antigen and αEβ7 Integrin (CD103) by CD8(+) T cells

summary:
[cell repeats an earlier one in this file: 251 characters]


id: cord-023390-5hcgdlmt
author: Bhuvanath, S.
title: Inflammatory Cytokine Modulation of Cancer Cell Proliferation
date: 2008-06-28
extension: .txt
mime: text/plain
words: 16839
sentence: 766
flesch: 44
cache: cache/cord-023390-5hcgdlmt.txt
txt: txt/cord-023390-5hcgdlmt.txt
summary:
  Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment. Findings in this project could provide an insight of cancer cell response to these cytokines and this could lead to a consideration on using cytokine as immunotherapy for cancer treatment.


id: cord-322933-5xnxjqm5
author: Murugaiah, Valarmathy
title: Collectins: Innate Immune Pattern Recognition Molecules
date: 2020-03-10
extension: .txt
mime: text/plain
words: 19410
sentence: 587
flesch: 32
cache: cache/cord-322933-5xnxjqm5.txt
txt: txt/cord-322933-5xnxjqm5.txt
summary:
  A study by Madan et al. has focused on the susceptibility of SP-A −/− and SP-D −/− mice to challenge with A. fumigatus allergen compared to wild-type mice (Madan et al. 2005a, b) . The helix interacts with a neighbouring carbohydrate recognition domains (Kishore et al. 2006; Skjoedt et al 2012)


# ent

id: cord-023394-ptfjxpo6
sid: 109
eid: 2
type: PRODUCT
entity:
  .................................................................................................................................................................................................


# pos

id: cord-023443-pvz7dll9
sid: 393
tid: 23
pos: PUNCT
token:
  ..................................................................................................................................................................................................

lemma:
  ..................................................................................................................................................................................................


