        item: #1 of 68
          id: cord-010965-5jkau3jb
      author: Berg-Weger, M.
       title: Loneliness in Old Age: An Unaddressed Health Problem
        date: 2020-01-16
       words: 1663
      flesch: 36
     summary: Loneliness and social connections Interventions for alleviating loneliness among older persons: A critical review High prevalence and adverse health effects of loneliness in community-dwelling adults across the lifespan: Role of wisdom as a protective factor Social contacts and their relationship to loneliness among aged people-a population-based study Predictors and subjective causes of loneliness in an aged population Incontinence and loneliness among Chinese older adults with multimorbidity in primary care: A cross-sectional study The impact of sensory impairment on cognitive performance, quality of life, depression, and loneliness among older adults The effectiveness and harms of antidepressants Cognitive deficit reversal as shown by changes in the Veterans Affairs Saint Louis University Mental Status (SLUMS) examination scores 7.5 years later Cognitive stimulation therapy Editorial: Nonpharmacological treatment of cognitive impairment Social contacts and their relationship to loneliness among aged people -a population-based study A systematic review of interventions for loneliness among older adults living in long-term care facilities Geriatric rehabilitation nursing: Developing a model Circle of Friends. Loneliness and social isolation have been shown to significantly impact older adults, both physically and emotionally.
    keywords: adults; friends; health; loneliness; persons
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        item: #2 of 68
          id: cord-011062-ukz4hnmy
      author: None
       title: Poster
        date: 2020-03-11
       words: 88442
      flesch: 49
     summary: Greater grip strength was associated with lower % of body fat and higher % of muscle mass. Conclusion: Older adult patients hospitalized for hip fracture who had frailty, functional dependence, and social problems had significant adverse events at a general hospital in Lima, Peru.
    keywords: activities; activity; adults; age; aging; analysis; assessment; association; background; baseline; bmi; body; care; cognitive; cohort; community; conclusion; criteria; cross; daily; data; day; decline; differences; disability; disease; dwelling; effect; elderly; exercise; factors; falls; fat; follow; frailty; frailty index; frailty screening; frailty status; function; gait; geriatric; grip; grip strength; group; health; high; hospital; impairment; increase; individuals; intake; intervention; level; life; living; loss; low; mean; measures; methods; model; months; mortality; muscle; muscle function; muscle health; muscle mass; muscle strength; non; obesity; objectives; outcomes; p<0.001; participants; patients; people; performance; physical; population; prevalence; program; protein; quality; regression; results; risk; sample; sarcopenia; score; screening; sex; speed; sppb; studies; study; subjects; surgery; test; time; total; training; university; vs.; walking; weight; women; years
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        item: #3 of 68
          id: cord-011302-pfepyvaw
      author: Edlmann, Ellie
       title: The changing face of neurosurgery for the older person
        date: 2020-04-25
       words: 3897
      flesch: 37
     summary: The barrow ruptured aneurysm Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial National Institute for Health and Clinical Excellence (NICE) (2014) Head injury: assessment and early management clinical guidelines [CG176 Subarachnoid haemorrhage in patients %3e or = 75 years: clinical course, treatment and outcome The impact of pre-operative comprehensive geriatric assessment on postoperative outcomes in older patients undergoing scheduled surgery: a systematic review A global clinical measure of fitness and frailty in elderly people International subarachnoid aneurysm trial of neurosurgical clipping versus endovascular coiling Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial Minimally invasive surgery for intracerebral hemorrhage Aneurysmal subarachnoid hemorrhage in elderly patients: long-term outcome and prognostic factors in an interdisciplinary treatment approach Importance of frailty evaluation in the prediction of the prognosis of patients with chronic subdural hematoma Oertel Matthias F (2012) Intracerebral hemorrhage in the Very Old Endovascular treatment of intracranial aneurysms in elderly patients Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis The MRC CRASH trial collaborators (2020) However, poor outcomes still prevail in older patients with emergency presentations: Whitehouse reported 5-year mortality of around 55% in neurosurgical patients over 65 admitted as an emergency compared with less than 20% in elective patients [42] .
    keywords: age; frailty; outcome; patients; treatment; trial; years
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        item: #4 of 68
          id: cord-016301-vqmqnipq
      author: Winnick, Aaron M.
       title: Elderly Transplant Recipients
        date: 2011-01-25
       words: 11468
      flesch: 38
     summary: Age and immune response in organ transplantation Immunosuppression of the elderly kidney transplant recipient Rejection and recipient age Use of mycophenolate mofetil in immunosuppressive protocols in elderly renal transplant recipients Mycophenolate mofetil vs. azathioprine in a large population of elderly renal transplant patients Immunosuppression: evolution in practice and trends Risk factors for development of new-onset diabetes mellitus after kidney transplantation A calcineurin antagonist-free induction/maintenance strategy for immunosuppression in elderly recipients of renal allografts from elderly cadaver donors: long-term results from a prospective single centre trial Long-term results of calcineurin-free protocols with basiliximab induction in old-toold programs Preferential allocation of marginal kidney allografts to elderly recipients combined with modified immunosuppression gives good results Early mortality rates in older kidney recipients with comorbid risk factors Renal transplantation in the elderly: surgical complications and outcome with special emphasis on the Eurotransplant Senior Programme Liver transplantation trends for older recipients: regional and ethnic variations Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis Liver transplantation in patients over sixty years of age Orthotopic liver transplantation in patients 60 years of age and older Orthotopic liver transplantation in patients over 60 years old Liver transplantation in patients over 60 years of age Liver transplantation in patients over sixty years of age Liver transplantation in patients over 60 and 65 years: an evaluation of long-term outcomes and survival Liver transplant for the septuagenarians: importance of patient selection Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases MELD and PELD: application of survival models to liver allocation Predicting outcome after liver transplantation: utility of the model for endstage liver disease and a newly derived discrimination function Impact of age older than 60 years in living donor liver transplantation Older age and liver transplantation: a review The prevalence of coronary artery disease in liver transplant candidates over age 50 The elderly liver transplant recipient: a call for caution Liver transplant recipients older than 60 years have lower survival and higher incidence of malignancy Allograft survival following adult-to-adult living donor liver transplantation Outcomes of 385 adult-to-adult living donor liver transplant recipients: a report from the A2ALL Consortium Long-term results of liver transplantation in older patients 60 years of age and older Liver transplantation in patients beyond age 60 Liver transplantation in recipients over 60 Similar outcomes, morbidity, and mortality for orthotopic liver transplantation between the very elderly and the young Evolution of liver transplantation in Europe: report of the European Liver Transplant Registry Prognostic model for early acute rejection after liver transplantation Age and liver transplantation: a report of the Liver Transplantation Database Transplantation in the elderly patient The registry of the International Society for Heart and Lung Transplantation: twentieth official adult heart transplant report -2003 Heart transplantation in patients seventy years of age and older: a comparative analysis of outcome Long-term survival (>10 years) of patients >60, years with induction therapy after cardiac transplantation Long-term results of heart transplantation in patients older than 60 years Outcomes in patients older than 60 years of age undergoing orthotopic heart transplantation: an analysis of the UNOS database Listing criteria for heart transplantation: International Society for Heart and Lung Transplantation guidelines for the care of cardiac transplant candidates -2006 Selection and treatment of candidates for heart transplantation. Heart transplantation in older candidates A comparative analysis of outcome after heart transplantation in patients aged 60 years and older: the University of Alberta experience Long-term outcomes of heart transplantation in older recipients Poor prognosis of heart transplant patients with end-stage renal failure Incidence of malignancies in heart and/or lung transplant recipients: a single-institution experience Registry of the International Society for Heart and Lung Transplantation: twentyfifth official adult lung and heart/lung transplantation report -2008 Assessment of survival benefit after lung transplantation by patient diagnosis Listing for lung transplantation: life expectancy and transplant effect, stratified by type of end-stage lung disease, the Eurotransplant experience International guidelines for the selection of lung transplant candidates: 2006 update -a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation Induction immunosuppression for lung transplantation with OKT3 Induction therapy in lung transplantation: a prospective, controlled clinical trial comparing OKT3, anti-thymocyte globulin, and daclizumab Registry of the International Society for Heart and Lung Transplantation: twentyfourth official adult lung and heart-lung transplantation report -2007 Impact of advanced age in lung transplantation: an analysis of United Network for Organ Sharing data Primary graft dysfunction and other selected complications of lung transplantation: a single-center experience of 983 patients Post-transplant bronchiolitis obliterans Development of malignancy following lung transplantation
    keywords: age; disease; donor; failure; heart; kidney; liver; lung; patients; recipients; rejection; renal; risk; survival; therapy; transplantation; years
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        item: #5 of 68
          id: cord-016840-p3sq99yg
      author: Bales, Connie Watkins
       title: Minimizing the Impact of Complex Emergencies on Nutrition and Geriatric Health: Planning for Prevention is Key
        date: 2008-09-09
       words: 7279
      flesch: 43
     summary: In recognition of the severe strain that a major disease outbreak can place on health systems, the World Health Organization (WHO) advocates for an 'integrated global alert and response system for epidemics and other public health emergencies' that allows for 'a collective approach to the prevention, detection, and timely response' for these emergencies (http://www.who.int/csr/en/). While terms like 'disaster relief' and 'humanitarian crisis' may be Any of a number of crisis situations that greatly elevate the health risk of individuals in the affected area; examples are natural disasters like floods and earthquakes; urban health emergencies like fires, epidemics, and blackouts; and terrorist acts like massive bombings or poisonings of food or water supplies.
    keywords: access; adults; care; emergencies; emergency; food; health; kits; medical; nutrition; people; persons; power; risk; water
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        item: #6 of 68
          id: cord-017461-xw02c7u5
      author: Kauffman, Carol A.
       title: Fungal Infections
        date: 2009-02-02
       words: 5448
      flesch: 35
     summary: Factors that predispose older patients to the development of oropharyngeal candidiasis include xerostomia, broad-spectrum antibiotics, inhaled corticosteroids, and dentures (1) . In older patients who have cryptococcal meningitis, mortality appears to be increased (7) .
    keywords: adults; aspergillosis; candida; coccidioidomycosis; histoplasmosis; infection; patients; pulmonary; risk; species; therapy
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        item: #7 of 68
          id: cord-018363-qr1pk78u
      author: Casey, Ashley
       title: Consultative and Comanagement
        date: 2015-10-10
       words: 19245
      flesch: 58
     summary: Answer: C Patients who have undergone signifi cant bowel resection should receive acid suppression in the postoperative period with a proton pump inhibitor. Answer: D Patients with -RA presenting for TKR represent those patients who have failed medical management and are a high-risk group for cervical spine involvement.
    keywords: answer; benefi; blood; bowel; cancer; daily; days; disease; dose; examination; following; heart; history; hospital; mortality; oral; pain; patient; rate; risk; surgery; syndrome; therapy; treatment; tube; warfarin; year
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        item: #8 of 68
          id: cord-025246-zah72cd6
      author: Lai, Daniel W. L.
       title: Revisiting Social Work with Older People in Chinese Contexts from a Community Development Lens: When East Meets West
        date: 2020-03-13
       words: 6499
      flesch: 35
     summary: At the individual level, older people, including Chinese older people, face physical, social, and psychological challenges associated with increased age. At the societal level, challenges facing older people, including Chinese older people, may be associated with environment, infrastructure, and wider social network dynamics.
    keywords: china; chinese; community; community development; development; empowerment; people; practice; workers
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        item: #9 of 68
          id: cord-033736-bsmqqi6j
      author: Bajraktari, Saranda
       title: Health-promoting and preventive interventions for community-dwelling older people published from inception to 2019: a scoping review to guide decision making in a Swedish municipality context
        date: 2020-10-14
       words: 10551
      flesch: 37
     summary: To summarise intervention effects, we classified health outcomes in broader categories (Table 3) . However, these findings on long-term effects are in contrast to a previous PHV trial that indicated that intervention effects remained only for as long as the home visits were ongoing [111] , and thus, highlights the importance of long term follow-ups over.
    keywords: community; cost; dwelling; effects; exercise; group; health; home; interventions; people; prevention; review; studies; study; trial
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        item: #10 of 68
          id: cord-034435-yp0gfl47
      author: Medetalibeyoglu, A.
       title: Older Adults Hospitalized with Covid-19: Clinical Characteristics and Early Outcomes from a Single Center in Istanbul, Turkey
        date: 2020-10-08
       words: 4768
      flesch: 43
     summary: In conclusion, this study shows that older Covid-19 patients that were hospitalized presented with more prevalent chronic comorbidities, less prevalent symptomatology (i.e., cough and fever) but more severe respiratory signs and laboratory abnormalities than the younger patients. In the radiological evaluation, more than half of the patients (54.6%) had moderate-severe pneumonia, which was more prevalent in older patients (66% vs. 50%) (p=0.006).
    keywords: adults; covid-19; disease; laboratory; mortality; patients; pneumonia; study
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        item: #11 of 68
          id: cord-034438-9kdmljoq
      author: Sepúlveda-Loyola, W.
       title: Impact of Social Isolation Due to COVID-19 on Health in Older People: Mental and Physical Effects and Recommendations
        date: 2020-09-25
       words: 4723
      flesch: 32
     summary: The social distancing has reduced the levels of physical activity, which could have a negative impact on physical health (43, 44) . A 10-year follow-up of the Aichi Gerontological Evaluation Study Associations between social isolation, loneliness, and objective physical activity in older men and women Social isolation, C-reactive protein, and coronary heart disease mortality among community-dwelling adults Loneliness and risk of mortality: a longitudinal investigation in Alameda County Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies Social isolation and physical inactivity in older US adults: Results from the Third National Health and Nutrition Examination Survey Sedentary Behavior Research Network (SBRN) -Terminology Consensus Project process and outcome Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research Sedentary behavior and health outcomes among older adults: a systematic review Physical activity in non-frail and frail older adults Replacing sedentary time with physical activity: a 15-year follow-up of mortality in a national cohort Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate-to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study The Feasibility and Longitudinal Effects of a Home-Based Sedentary Behavior Change Intervention After Stroke COVID-19, Mental Health and Aging: A Need for New Knowledge to Bridge Science and Service Declaration of Conflict of Interest: None.Declaration of Sources of Funding: co-financed by the European Regional Development Funds (RD120001/0043) and the Centro de Investigación Biomédica en Red en Fragilidad y Envejecimiento Saludable-CIBERFES (CB16/10/00464).Author's contribution: Study concept and design: all authors.
    keywords: activity; adults; covid-19; health; isolation; pandemic; participation; people; physical; review
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        item: #12 of 68
          id: cord-034443-rptylxmw
      author: Morley, John E.
       title: COVID-19 — The Long Road to Recovery
        date: 2020-10-05
       words: 1796
      flesch: 28
     summary: All persons with COVID-19 should have bioavailable 25(OH) vitamin D measured (15) as during lockdown lack of sunlight can markedly reduce vitamin D in COVID-19 patients (16) . Nature (News feature) Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery Back to basics: Giant challenges to addressing Isaac's Geriatric Giants post COVID-19 crisis COVID-19 and associations with frailty and multimorbidity: A prospective analysis of UK Biobank participants The association between frailty and severe disease among COVID-19 patients aged over 60 years in China: A prospective cohort study COVID-19: A major cause of cachexia and sarcopenia?
    keywords: care; covid-19; delirium; patients; persons; study
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        item: #13 of 68
          id: cord-252854-gl094y6c
      author: Cesari, Matteo
       title: COVID-19 and Older Adults. Lessons Learned from the Italian Epicenter
        date: 2020-03-01
       words: 2329
      flesch: 54
     summary: Do older patients with severe COVID-19 illness present with severe dyspnea and hypoxemia, as do the younger adults? Or do older patients present with geriatric syndromes, such as delirium?
    keywords: adults; care; cases; italy; patients
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        item: #14 of 68
          id: cord-253182-s60vzf3q
      author: Fang, Evandro F.
       title: A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
        date: 2020-09-21
       words: 23336
      flesch: 37
     summary: Rapid ageing and an alarming increase in non-communicable diseases (NCDs) have arisen as major health concerns in China Marten et al., 2014) . Fourthly, a reform of the payment model used in elderly care services should be carried out, focusing on value rather than volume of care for populations at risk of care dependency.
    keywords: adults; ageing; care; china; chinese; clinical; community; data; dementia; development; diseases; et al; factors; family; fig; frailty; government; health; healthcare; hiv; insurance; level; life; mortality; national; patients; people; population; prevalence; research; risk; sarcopenia; services; society; studies; study; system; treatment; use; years
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        item: #15 of 68
          id: cord-253735-0wi67tuw
      author: Niu, Shengmei
       title: Clinical characteristics of older patients infected with COVID-19: A descriptive study
        date: 2020-04-10
       words: 2929
      flesch: 46
     summary: key: cord-253735-0wi67tuw authors: Niu, Shengmei; Tian, Sijia; Lou, Jing; Kang, Xuqin; Zhang, Luxi; Lian, Huixin; Zhang, Jinjun title: Clinical characteristics of older patients infected with COVID-19: This study focused on older patients with COVID-19 infection and analyzed the epidemiological and clinical characteristics of them.
    keywords: covid-19; infection; patients; study; years
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        item: #16 of 68
          id: cord-253900-ftwuybud
      author: Mulas, Ilaria
       title: Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors
        date: 2020-09-25
       words: 6646
      flesch: 34
     summary: Normative spatiotemporal gait parameters in older adults Gait and cognition: a complementary approach to understanding brain function and the risk of falling Cognitive contributions to gait and falls: evidence and implications: cognitive contributions to gait and falls Motoric cognitive risk syndrome and the risk of dementia Properties of the 'timed up and go' test: more than meets the eye A systematic review of thirty-one assessment tests to evaluate mobility in older adults Up & Go: a test of basic functional mobility for frail elderly persons Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go test The reliability and validity of the timed Up and Go as a clinical tool in individuals with and without disabilities across a lifespan: a systematic review: psychometric properties of the Timed Up and Go Stages of mild cognitive impairment and Alzheimer's disease can be differentiated by declines in Timed Up and Go test: a systematic review and meta-analysis Timed Up and Go' test: age, gender and cognitive impairment stratified normative values of older adults Global cognitive functioning and physical mobility in older adults with and without mild cognitive impairment: evidence and implications Cognitive correlates of timed up and go subtasks in older people with preserved cognition mild cognitive impairment, and Alzheimer's disease Performance of an adapted version of the Timed Up-and-Go test in people with cognitive impairments The utility of the Timed Up-and-Go test in predicting cognitive performance: a cross-sectional study of independent living adults in a retirement community Neurological gait disorders in elderly people: clinical approach and classification Laboratory review: the role of gait analysis in seniors' mobility and fall prevention Efficacy of clinical gait analysis: a systematic review Are cost-effective technologies feasible to measure gait in older adults? The CI-YO group was characterized by reduced gait speed and stride length with respect to HC-YO (p < 0.001) and healthy individuals of different age ranges differed only as regards gait speed (p < 0.001).
    keywords: ace; adults; analysis; gait; impairment; individuals; mobility; parameters; speed; study; test; tug
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        item: #17 of 68
          id: cord-258093-6fn8ei9f
      author: Hanania, Nicola A.
       title: Asthma in the elderly: Current understanding and future research needs—a report of a National Institute on Aging (NIA) workshop
        date: 2011-08-25
       words: 17068
      flesch: 41
     summary: The aging lung Large, longitudinal, and more complete studies to determine the effects of aging on the function of the respiratory system Improved knowledge about lung structure-function relationships in older age using techniques of imaging and measures of lung function not requiring effort (eg, high-resolution computed tomographic scanning and forced oscillation) Improved assessment of lung processes underlying airflow limitation attributable to aging versus COPD or asthma, especially in asthmatic patients who smoke Studies to examine the effects of aging in ethnic groups and the role of gender Epidemiology, effect, diagnosis, and management Determine the true prevalence and cost of asthma in the older population Develop a uniform definition of asthma to be applied to health care records that will distinguish asthma from COPD and mixed asthma/COPD Evaluate evidence-based treatment algorithms for older asthmatic patients, such as those developed by the National Heart, Lung, and Blood Institute and Global Initiative For Asthma guidelines 7 Assess the effect of asthma treatment, including direct medical costs of care, indirect costs of care, and value of treatment in improving quality of life 8, 9 Assess the effect of comorbid conditions, especially COPD and congestive heart failure, on asthma 9 Characterize phenotypes of elderly asthma with regard to responses to therapy and long-term outcomes based on age of onset, duration of disease, and environmental triggers Develop algorithms for electronic medical record systems that are asthma-specific Evaluate effects of current asthma medications in older patients compared with younger patients Identify pharmacogenetic determinants of response to asthma medications in older adults Identify simpler and safer drug delivery systems and schedules for older adults Develop simple methods to differentiate COPD from asthma exacerbations in older adults Understand how environmental or aging-related factors affect epigenetic changes in asthma in older adults Identify differences between older and younger asthmatic patients or between LSA and LOA with regard to inflammation, remodeling, intracellular mechanisms, responses to environmental pollutants, and allergy sensitization and their effects on the metabolism and action of asthma drugs Identify naturally occurring age-related changes in airway cellular patterns Develop animal models of age-related airway inflammation Understand the significance of allergy sensitization associated with asthma in older adults (eg, through larger prospective studies) 97, 124, 128 Patients with LOA start having asthma symptoms for the first time when they are 65 years of age or older (some studies have suggested middle age or older).
    keywords: adults; age; aging; airway; asthma; care; changes; control; copd; diagnosis; disease; effects; elderly; function; group; health; inflammation; life; lung; patients; population; response; studies; study; subjects; symptoms; treatment; years
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        item: #18 of 68
          id: cord-258915-lgee3ers
      author: Liddle, Jennifer
       title: Connecting at Local Level: Exploring Opportunities for Future Design of Technology to Support Social Connections in Age-friendly Communities
        date: 2020-07-31
       words: 12518
      flesch: 41
     summary: Based on the in-depth understanding about participants' use and perceptions of technology that we gained from the interviews, we designed 'playful' workshop activities that deliberately did not ask participants explicitly to consider how technology could address issues in local social connections. The workshop was structured around four opportunities to improve local social connections that we identified as themes through our interview analysis.
    keywords: activities; age; area; community; connections; design; face; ideas; participants; people; relationships; technology; themes; use; workshop
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        item: #19 of 68
          id: cord-259560-mmz5vn0q
      author: Price, Sarah
       title: Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006–17
        date: 2020-09-09
       words: 3841
      flesch: 46
     summary: Achieving World-Class Cancer Outcomes: Taking the Strategy Forward Suspected Cancer: Recognition and Referral Cancer patient pathways in Denmark as a joint effort between bureaucrats, health professionals and politicians-a national Danish project The 2015 National Cancer Program in Sweden: Introducing standardized care pathways in a decentralized system Routes to Diagnosis The expanding role of primary care in cancer control National Institute for Health and Clinical Excellence, Referral Guidelines for Suspected Cancer Ovarian Cancer: Initial Recognition and Management Symptom signatures and diagnostic timeliness in cancer patients: a review of current evidence Department of Health, Northern Ireland Referral Guidance for Suspected Cancer, Department of Health Cancer suspicion in general practice, urgent referral and time to diagnosis: a population-based GP survey and registry study Age and gender variations in cancer diagnostic intervals in 15 cancers: analysis of data from the UK clinical practice research datalink Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database Cancer suspicion in general practice, urgent referral and time to diagnosis: a population-based GP survey and registry study Diffusion of innovations in service organizations: systematic review and recommendations The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients Scottish Referral Guidelines for Suspected Cancer Identifying clinical features in primary care electronic health record studies: methods for codelist development The Aarhus statement: improving design and reporting of studies on early cancer diagnosis Measuring the impact of national guidelines: what methods can be used to uncover time-varying effects for healthcare evaluations? Policymakers are urged to enhance cancer diagnostic services so that they do not pose a rate-limiting step in the diagnostic pathway, and to protect them from the pressures of Covid-19.
    keywords: cancer; days; diagnosis; features; guidance; intervals; participants
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        item: #20 of 68
          id: cord-259618-kl0aq0ut
      author: De Leo, Diego
       title: The fight against COVID-19: a report from the Italian trenches
        date: 2020-04-20
       words: 2509
      flesch: 48
     summary: A discrepancy between the gift of a long life and public acceptance of older adults is increasingly noticeable and clearly expressed by the deprecated document on damages caused by longevity, which Christine Lagarde (now the president of the European Central Bank) spoke about a few years ago (2012): Old people live too long and this is a risk for the global economy. Those Tickets in Front of the House Telecommunication and suicide prevention: hopes and challenges for the new century Presentation of the Global Financial Stability Report The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients The value of maintaining social connections for mental health in older people
    keywords: care; covid-19; health; italy; patients; people
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        item: #21 of 68
          id: cord-260046-lli6mt29
      author: Garnier‐Crussard, Antoine
       title: Novel Coronavirus (COVID‐19) Epidemic: What Are the Risks for Older Patients?
        date: 2020-03-12
       words: 783
      flesch: 44
     summary: key: cord-260046-lli6mt29 authors: Garnier‐Crussard, Antoine; Forestier, Emmanuel; Gilbert, Thomas; Krolak‐Salmon, Pierre title: Novel Coronavirus (COVID‐19) Epidemic: What Are the Risks for Older Patients? date: 2020-03-12 journal: J Am Geriatr Soc DOI: 10.1111/jgs.16407 sha: doc_id: 260046 cord_uid: lli6mt29 nan The World Health Organization confirmed 93,090 cases of novel coronavirus SARS-CoV-2 infections (COVID-19) worldwide on March 04, 2020. Therefore, it seems essential to limit the risk of spreading the virus in facilities caring for older patients at all costs.
    keywords: adults; care; patients
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        item: #22 of 68
          id: cord-261733-kc0d5pe8
      author: Galili, Uri
       title: Why Do We Produce Anti-Gal: Evolutionary Appearance of Anti-Gal in Old World Primates
        date: 2017-09-15
       words: 9420
      flesch: 31
     summary: Increased immunogenicity of human immunodeficiency virus gp120 engineered to express Galα1-3Galβ1-4GlcNAc-R epitopes Increased immunogenicity of influenza virus vaccine by anti-Gal mediated targeting to antigen presenting cells Increased immunogenicity of HIV-1 p24 and gp120 following immunization with gp120/p24 fusion protein vaccine expressing α-gal epitopes Explaining the end of the hominoid experiment in Europe Fossil apes from the Vallès-Penedès basin Complement-mediated lysis of Trypanosoma cruzi trypomastigotes by human anti-α-galactosyl antibodies Lytic anti-α-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi Hominoid dietary evolution Evolution and environment in the Hominoidea Distribution and biochronology of European and southwest Asian Miocene catarrhines Immunogenic Galα1-3Gal carbohydrate epitopes are present on pathogenic American Trypanosoma and Leishmania Bombay (Oh) phenotype among the Kutia Kondh primitive tribe of Orissa Bombay (Oh) phenotype, in Bhuyan tribe of Northwestern Orissa Enzymatic synthesis of blood group related pentaglycosyl ceramide by an α-galactosyltransferase The influence of natural antibody specificity on antigen immunogenicity Ig knock-in mice producing anticarbohydrate antibodies: breakthrough of B cells producing low affinity anti-self antibodies Two α-3-D galactosyltransferases in rabbit stomach mucosa with different acceptor substrate specificities A new blood group character related to the ABO system An α-D-galactosyltransferase in Ehrlich ascites tumor cells: Biosynthesis and characterization of a trisaccharide (α-D-galacto(1-3)-N-acetyllactosamine) Biosynthesis of terminal Galα1-3Galß1-4GlcNAc-R oligosaccharide sequence on glycoconjugates: purification and acceptor specificity of a UDP-Gal: N-acetyllactosamine α1,3galactosyltransferase Printed covalent glycan array for ligand profiling of diverse glycan binding proteins Natural antibodies to glycans Repertoire of human natural anti-glycan immunoglobulins. It is suggested that prior to such epidemics, few ancestral Old World primates acquired deletion point mutations that inactivated the α1,3GT gene and eliminated α-gal epitopes.
    keywords: anti; antibodies; antibody; blood; carbohydrate; epitopes; et al; gal; gene; group; primates; virus; world; α1,3gt
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        item: #23 of 68
          id: cord-265655-s5c7r6ix
      author: Krendl, Anne C
       title: The Impact of Sheltering in Place During the COVID-19 Pandemic on Older Adults’ Social and Mental Well-Being
        date: 2020-08-11
       words: 3427
      flesch: 45
     summary: The relation between social network site usage and loneliness and mental health in community-dwelling older adults COVID-19 worries and behavior changes in older and younger men and women Examining social media use among older adults Social contagion and innovation: Cohesion versus structural equivalence Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations Study COVID-19 in racial and ethnic minority groups PHQ-8 days: A measurement option for DSM-5 Major Depressive Disorder (MDD) severity Selective narrowing of social networks across adulthood is associated with improved emotional experience in daily life G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences Minimental state. We examined whether social isolation due to the COVID-19 shelter-in-place orders was associated with greater loneliness and depression for older adults, and, if so, whether declines in social engagement or relationship strength moderated that relationship.
    keywords: adults; depression; loneliness; social; time
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        item: #24 of 68
          id: cord-265830-6shiocwr
      author: Frost, Rachael
       title: Using remote interventions in promoting the health of frail older persons following the COVID-19 lockdown: challenges and solutions
        date: 2020-05-25
       words: 978
      flesch: 39
     summary: 9 Evidence of effectiveness for remote interventions for frail older people is promising, but very 10 limited at present. 4 Similarly, for 14 malnourished older people, phone-based nutrition interventions with dieticians improved protein 15 intake and quality of life but not other outcomes in one systematic review of nine studies.
    keywords: face; interventions; people
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        item: #25 of 68
          id: cord-266239-l0ulr2ep
      author: Freeman, Shannon
       title: Intergenerational Effects on the Impacts of Technology Use in Later Life: Insights from an International, Multi-Site Study
        date: 2020-08-07
       words: 6852
      flesch: 46
     summary: The findings contribute to the growing literature in the fields of gerontology and gerontechnology on intergenerational influences and the impacts of technology use in later life and suggest the flexibility and willingness of older persons to adopt to new technologies as well as the value of intergenerational relationships for overcoming barriers to technology adoption. Technology use among older adults is growing [3] .
    keywords: adults; age; family; life; members; participants; relationships; social; study; technologies; technology; use
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        item: #26 of 68
          id: cord-269716-x3b0qphd
      author: Hopper, Lydia M.
       title: Problem solving flexibility across early development
        date: 2020-08-26
       words: 10333
      flesch: 51
     summary: Although 2-year-olds struggle with more cognitively demanding physical adaptation of these looking-time studies, by 3 years of age children are able to track a falling object behind an occluder, correctly select a door to open, and reach for the fallen object (Berthier, DeBlois, Poirier, Novak, & Clifton, 2000) . To determine the diversity of action sequences children used, we calculated the diversity index of their responses (Shannon & Weaver, 1949) .
    keywords: action; ball; children; flexibility; olds; phase; straws; task; trial; year
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        item: #27 of 68
          id: cord-273612-o746vjrn
      author: Isaacson, Michal
       title: Mobility scooters in urban environments: A research agenda
        date: 2020-09-30
       words: 3292
      flesch: 46
     summary: key: cord-273612-o746vjrn authors: Isaacson, Michal; Barkay, Dov title: Mobility scooters in urban environments: A research agenda date: 2020-09-30 journal: Journal of Transport & Health DOI: 10.1016/j.jth.2020.100917 sha: doc_id: 273612 cord_uid: o746vjrn Abstract Introduction As our society ages, mobility scooters are a fast-growing mode of transportation. Mobility scooters require appropriate parking facilities: Once reaching a destination, mobility scooters need dedicated space in which to be parked safely.
    keywords: mobility; people; scooters; use; users
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        item: #28 of 68
          id: cord-274858-rx7dlpid
      author: Payne, Brian K.
       title: Criminals Work from Home during Pandemics Too: a Public Health Approach to Respond to Fraud and Crimes against those 50 and above
        date: 2020-06-06
       words: 5647
      flesch: 57
     summary: A wide variety of prevention and intervention strategies have been used to reduce the risk of victimization for older abuse. Specifically, 18% of coronavirus fraud victims were in their sixties, though they make up just 11.5% of the population.
    keywords: abuse; age; coronavirus; elder; fraud; ftc; health; nursing; pandemic; persons; risk
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        item: #29 of 68
          id: cord-278423-tluo3ztc
      author: Strozza, Cosmo
       title: Health profiles and socioeconomic characteristics of nonagenarians residing in Mugello, a rural area in Tuscany (Italy)
        date: 2020-08-15
       words: 5755
      flesch: 47
     summary: The use of LCA in population health studies is extensive, with applications that vary from younger To capture the heterogeneity of health status and evaluate the social disparities among individuals, researchers suggest the use of latent class analysis (LCA) as a person-centered approach [11]
    keywords: analysis; class; group; health; individuals; nonagenarians; status; study
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        item: #30 of 68
          id: cord-279631-1hlrx7o4
      author: Huang, Yan‐Mei
       title: CHINA'S OLDEST CORONAVIRUS SURVIVORS
        date: 2020-04-08
       words: 1548
      flesch: 50
     summary: The isolation of nursing home patients has led to some negative consequences. Nursing home patients in particular have higher rates of dementia, delirium, and behavioral issues 8 that require greater nursing care, which is challenging in isolation facilities, especially in the context of a global pandemic.
    keywords: coronavirus; covid-19; nursing; patients; year
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        item: #31 of 68
          id: cord-281344-iswbgqqe
      author: Jonker, Leonie T.
       title: Perioperative telemonitoring of older adults with cancer: Can we connect them all?
        date: 2020-09-04
       words: 3936
      flesch: 33
     summary: Although the increasing cancer incidence in older patients is widely recognised, older patients remain underrepresented in clinical cancer trials and eHealth studies. This is a retrospective analysis of a prospective cohort study with older patients (≥ 65 years) undergoing cancer-related surgery, who were identified for a perioperative telemonitoring study.
    keywords: cancer; data; hospital; non; participants; patients; study
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        item: #32 of 68
          id: cord-281877-r1y1hz4q
      author: Lavretsky, Helen
       title: Scientific Autobiography of a Spiritual Seeker in the Year of Hindsight's 20/20.: “Was I deceived, or did a sable cloud Turn forth her silver lining on the night?” John Milton “Comus” (1634)
        date: 2020-08-11
       words: 2688
      flesch: 42
     summary: A greater truth about that nature of late life mood and cognitive disorders will emerge from this collaboration and will be the source for new research ideas for years to come. In the later years, new research questions originated from my clinical experience.
    keywords: depression; health; mind; new; research; study; yoga
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        item: #33 of 68
          id: cord-283779-mudwcypl
      author: Lauretani, Fulvio
       title: Assessment and treatment of older individuals with COVID-19 multi-system disease: clinical and ethical implications
        date: 2020-05-11
       words: 9739
      flesch: 35
     summary: As a consequence of multimorbidity, polypharmacy defined as the number of drugs reported at hospital admission and the potential drug-drug interactions require a careful evaluation in older COVID-19 patients. These principles have been often ignored, especially in older COVID-19 patients.
    keywords: acute; care; coronavirus; covid-19; day; days; disease; infection; mortality; nutritional; patients; phase; pulmonary; risk; sars; symptoms; syndrome; treatment; use; virus
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        item: #34 of 68
          id: cord-284595-0mlwp05f
      author: Kirkpatrick, James N.
       title: Primary Prevention Statins in Older Patients: The Good News or the Bad News First?
        date: 2020-07-07
       words: 124
      flesch: 43
     summary: Association of statin use with disability-free survival and cardiovascular disease among healthy older adults Effect of aspirin on disability-free survival in the healthy elderly Effect of aspirin on cardiovascular events and bleeding in the healthy elderly Deprescribing in older adults with cardiovascular disease It is also relatively old news that statins reduce adverse cardiovascular outcomes, but it remains unclear whether this reduction applies to older adults.
    keywords: news
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        item: #35 of 68
          id: cord-285521-lvzdmtun
      author: Olagundoye, Olawunmi
       title: Recommendations for a national Coronavirus disease 2019 response guideline for the care of older persons in Nigeria during and post-pandemic: A family physician’s perspective
        date: 2020-08-11
       words: 1652
      flesch: 44
     summary: key: cord-285521-lvzdmtun authors: Olagundoye, Olawunmi; Enema, Oluwayemisi; Adebowale, Adunola title: Recommendations for a national Coronavirus disease 2019 response guideline for the care of older persons in Nigeria during and post-pandemic: A family physician’s perspective date: 2020-08-11 journal: Based on currently available information, older persons and people of any age who have serious underlying medical conditions may be at higher risk of severe illness from COVID-19.
    keywords: care; covid-19; health; persons
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        item: #36 of 68
          id: cord-288392-khjo6j8u
      author: Davern, Melanie
       title: How Can the Lived Environment Support Healthy Ageing? A Spatial Indicators Framework for the Assessment of Age-Friendly Communities
        date: 2020-10-21
       words: 8982
      flesch: 31
     summary: These include consultation and engagement with local older people themselves to expand understanding, prioritise actions, and support the greatest social and economic benefits and returns on investments that support improved health and quality of life for older people. The WHO Age-Friendly Cities Framework Best practice principles for community indicator systems and a case study analysis: How community indicators Victoria is creating impact and bridging policy, practice and research Age-friendly cities and communities: Access to services for older people Developing a research and practice tool to measure walkability: A demonstration project Transport Walkability Index: Melbourne.
    keywords: access; afc; age; ageing; communities; community; health; housing; indicators; people; planning; public; services; support; transport
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        item: #37 of 68
          id: cord-288479-ti9x8p6m
      author: Cobo, Antonio
       title: Automatic and Real-Time Computation of the 30-Seconds Chair-Stand Test without Professional Supervision for Community-Dwelling Older Adults
        date: 2020-10-14
       words: 11895
      flesch: 57
     summary: A 30-s Chair-Stand Test as a Measure of Lower Body Strength in Community-Residing Older Adults Frailty in Older Adults: Evidence for a Phenotype Unstable disability and the fluctuations of frailty Conceptualisation and Measurement of Frailty in Elderly People Frailty in elderly people Frailty as a predictor of disabilities among community-dwelling older people: A systematic review and meta-analysis Are We Living Longer and Healthier? A Physical Activity Intervention to Treat the Frailty Syndrome in Older Persons-Results From the LIFE-P Study Frailty in the clinical scenario Treating frailty-a practical guide Accumulation of Deficits as a Proxy Measure of Frailty in Relation to the Accumulation of Deficits Frailty Defined by Deficit Accumulation and Geriatric Medicine Defined by Frailty The Clinical Care of Frail, Older Adults Relationship between lower-limb muscle strength and frailty among elderly people A Short Physical Performance Battery Assessing Lower Extremity Function: Association with Self-Reported Disability and Prediction of Mortality and Nursing Home Admission Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study Sedentary Behavior as a Risk Factor for Physical Frailty Independent of Moderate Activity: Results from the Osteoarthritis Initiative A tale of two pandemics: How will COVID-19 and global trends in physical inactivity and sedentary behavior affect one another? Kinematic Parameters to Evaluate Functional Performance of Sit-to-Stand and Stand-to-Sit Transitions Using Motion Sensor Devices: A Systematic Review Standardization and definitions of the sit-stand-sit movement cycle Automated approach for quantifying the repeated sit-to-stand using one body fixed sensor in young and older adults Automatic Evaluation of the 30-s Chair Stand Test Using Inertial/Magnetic-Based Technology in an Older Prefrail Population An evaluation of the 30-s chair stand test in older adults: Frailty detection based on kinematic parameters from a single inertial unit Validation of seat-off and seat-on in repeated sit-to-stand movements using a single-body-fixed sensor Older Adults with Weaker Muscle Strength Stand up from a Sitting Position with More Dynamic Trunk Use A body-fixed-sensor-based analysis of stair ascent and sit-to-stand to detect age-related differences in leg-extensor power The Instrumented Sit-to-Stand Test (iSTS) Has Greater Clinical Relevance than the Manually Recorded Sit-to-Stand Test in Older Adults Gait Velocity and Chair Sit-Stand-Sit Performance Improves Current Frailty-Status Identification Sensor-based monitoring of sit-to-stand performance is indicative of objective and self-reported aspects of functional status in older adults Development of an Automated 30 Second Chair Stand Test Using Smartwatch Application Portable Ultrasound-Based Device for Detecting Older Adults' Sit-to-Stand Transitions in Unsupervised 30-Second Chair-Stand Tests Human activity recognition using thigh angle derived from single thigh mounted IMU data Ability of Thigh-Worn ActiGraph and activPAL Monitors to Classify Posture and Motion Probabilistic identification of sit-to-stand and stand-to-sit with a wearable sensor Quantifying sit-to-stand and stand-to-sit transitions in free-living environments using the activPAL thigh-worn activity monitor MEMS based IMU for tilting measurement: Comparison of complementary and kalman filter based data fusion Validation of Thigh Angle Estimation Using Inertial Measurement Unit Data against Optical Motion Capture Systems Wearable Goniometer and Accelerometer Sensory Fusion for Knee Joint Angle Measurement in Daily Life Functional Fitness Normative Scores for Community-Residing Older Adults, Ages 60-94 Development and Validation of Criterion-Referenced Clinically Relevant Fitness Standards for Maintaining Physical Independence in Later Years We would like to thank FEDER funds for co-financing our home institutions. In such a scenario (i.e., fewer visits to the doctor and increased risk of frailty due to sedentary behavior) older adults would benefit from having automatic sensors to conduct functional assessment exams at home, on their own or helped by their care givers.
    keywords: angle; cst; device; frailty; noise; sensor; sist; sitting; stand; study; subject; test; thigh; transitions
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        item: #38 of 68
          id: cord-292878-wbfi0v2x
      author: Merchant, Reshma A.
       title: The Role of a Geriatrician has Become Even More Important in an Academic Institution during COVID-19
        date: 2020-05-13
       words: 1158
      flesch: 42
     summary: Singapore is filled with high-rise housing with void decks on the ground floor built by the Housing Development Board (HDB), which used to be a meeting place for many older adults before the circuit breaker. While a lot of the resources are being channelled to manage the increasing numbers of COVID-19 patients, frail older adults with multimorbidity continue to be admitted with very complex needs.
    keywords: adults; covid-19; geriatricians; patients
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        item: #39 of 68
          id: cord-294115-7t7kubf6
      author: Miralles, Oriol
       title: Unmet needs, health policies, and actions during the COVID-19 pandemic: a report from six European countries
        date: 2020-10-15
       words: 7261
      flesch: 45
     summary: Address the disparities in pay and job security between health care and social care workers. As a result, at the beginning, 19 single-purpose infectious disease hospitals were established across the country for COVID-19 patients, supplemented by 70 infectious disease wards.
    keywords: age; care; cases; countries; cov-2; covid-19; health; homes; impact; march; nursing; pandemic; patients; people; sars; support
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        item: #40 of 68
          id: cord-303131-hnfu49x7
      author: Shaygan, Maryam
       title: Considerations for Mitigation of the Psychological Impacts of COVID-19 in Older Adults
        date: 2020-07-17
       words: 987
      flesch: 50
     summary: Here are some suggestions to help mitigate the consequences of quarantine among Shaygan M, Bahadori F ijcbnm.sums.ac.ir older adults: -Give older adults as much information as possible Older adults often have catastrophic appraisals of any physical symptoms they experience, which may further increase feelings of fear and anxiety. Mental health services for older adults in China during the COVID-19 outbreak Mental health status of people isolated due to Middle East Respiratory Syndrome The psychological impact of quarantine and how to reduce it: rapid review of the evidence
    keywords: adults; health; services
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        item: #41 of 68
          id: cord-305743-rnfn6opa
      author: Anton, Stephen D.
       title: Innovations in Geroscience to enhance mobility in older adults
        date: 2020-10-22
       words: 15996
      flesch: 32
     summary: The American journal of medicine The association between objectively measured sitting and standing with body composition: a pilot study using MRI Associations of physical activity and sedentary behavior with regional fat deposition Reduced physical activity increases intermuscular adipose tissue in healthy young adults Sedentary behavior, physical activity, and the metabolic syndrome among U.S. adults Low muscle mass in older men: the role of lifestyle, diet and cardiovascular risk factors Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study Obesity and mobility disability in the older adult Decreased functional capacity and muscle strength in elderly women with metabolic syndrome Prevalence of Metabolic Syndrome and Its Association with Physical Capacity, Disability, and Self-Rated Health Among Lifestyle Interventions for Elders (LIFE) Study Participants Sedentary and physically active behavior patterns among low-income African-American and white adults living in the southeastern United States The independent and combined associations of physical activity and sedentary behavior with obesity in adults: NHANES 2003-06 Sedentary time is associated with the metabolic syndrome in older adults with mobility limitations--The LIFE Study Why sleep is important for health: a psychoneuroimmunology perspective Prevalence of Healthy Sleep Duration among Adults--United States Sleep and Human Aging Frequent napping is associated with excessive daytime sleepiness, depression, pain, and nocturia in older adults: findings from the National Sleep Foundation '2003 Sleep in America' Poll Longitudinal relationship between sleep deficiency and pain symptoms among community-dwelling older adults in Japan and Singapore Cortical thickness mediates the association between self-reported pain and sleep quality in community-dwelling older adults Chronic Musculoskeletal Pain Moderates the Association between Sleep Quality and Dorsostriatal-Sensorimotor Resting State Functional Connectivity in Community-Dwelling Older Adults The National Institute on Aging Health Disparities Research Framework Effects of stress throughout the lifespan on the brain, behaviour and cognition Social Isolation and Loneliness in Older Adults: Opportunities for the Health Care System Associations between social isolation, loneliness, and objective physical activity in older men and women Social isolation, loneliness, and all-cause mortality in older men and women Social isolation, loneliness and health in old age: a scoping review Where we live: health care in rural vs urban America Differential access to care: The role of age, insurance, and income on race/ethnicity-related disparities in adult perforated appendix admission rates National dissemination of multiple evidence-based disease prevention programs: reach to vulnerable older adults Ethnicity-and socio-economic status-related stresses in context: an integrative review and conceptual model Determinants of Adherence in Time-Restricted Feeding in Older Adults: Lessons from a Pilot Study Older Adults' Perceptions of Mobility: A Metasynthesis of Qualitative Studies Frailty Phenotype: Evidence of Both Physical and Mental Health Components in Community-Dwelling Early-Old Adults Balance Confidence and Fear of Falling Avoidance Behavior Are Most Predictive of Falling in Older Adults: Prospective Analysis Self-efficacy, pain, and quadriceps capacity at baseline predict changes in mobility performance over 2 years in women with knee osteoarthritis Falls efficacy as a measure of fear of falling Dizziness and its association with walking speed and falls efficacy among older men and women in an urban population Falls and fear of falling: which comes first? A longitudinal prediction model suggests strategies for primary and secondary prevention Mobility device use in older adults and incidence of falls and worry about falling: findings from the 2011-2012 national health and aging trends study Effects of supervised slackline training on postural instability, freezing of gait, and falls efficacy in people with Parkinson's disease A Backward Walking Training Program to Improve Balance and Mobility in Acute Stroke: A Pilot Randomized Controlled Trial Integrated primary and geriatric care for frail older adults in the community: Implementation of a complex intervention into real life Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss One-Year Adherence to the Otago Exercise Program With or Without Motivational Interviewing in Community-Dwelling Older Adults Walking can be more effective than balance training in fall prevention among community-dwelling older adults The Effect of Yoga on Balance and Fear of Falling in Older Adults Motivating Older Adults with Cancer to Keep Moving: the Implications of Lifestyle Interventions on Physical Activity Attitudes and needs of residents in long-term care facilities regarding physical activity-A systematic review and synthesis of qualitative studies Enablers and barriers to older people's participation in strength and balance activities: A review of reviews Integrated care for geriatric frailty and sarcopenia: a randomized control trial The retardation of aging by caloric restriction: studies in rodents and primates Dietary restriction and lifespan: Lessons from invertebrate models Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans Calorie restriction or exercise: effects on coronary heart disease risk factors.
    keywords: activity; adults; age; aging; brain; changes; chronic; community; decline; disability; disease; effects; factors; function; health; interventions; life; loss; mobility; muscle; oxytocin; pain; r n; research; risk; sleep; study
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        item: #42 of 68
          id: cord-306210-ny3vvu9h
      author: Clarfield, A. Mark
       title: Age, ageing, ageism and “age-itation” in the Age of COVID-19: rights and obligations relating to older persons in Israel as observed through the lens of medical ethics
        date: 2020-11-12
       words: 9583
      flesch: 52
     summary: Without this aid it is difficult for such older persons to cope with social isolation and resulting loneliness. key: cord-306210-ny3vvu9h authors: Clarfield, A. Mark; Jotkowitz, Alan title: Age, ageing, ageism and “age-itation” in the Age of COVID-19: rights and obligations relating to older persons in Israel as observed through the lens of medical ethics date: 2020-11-12 journal:
    keywords: age; ageism; covid-19; disease; example; health; icu; israel; medical; pandemic; people; persons; ref; risk; society
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        item: #43 of 68
          id: cord-306504-0wq7rc6s
      author: Barakovic Husic, Jasmina
       title: Aging at Work: A Review of Recent Trends and Future Directions
        date: 2020-10-20
       words: 6414
      flesch: 48
     summary: active aging at work, older adults at work, successful aging at work, healthy aging at work, productive aging at work Motivations deficit, discrimination, growth Solutions EU policy, assistance schemes, eligibility criteria, legislation, national policy active aging at work healthy aging at work older adults at work productive aging at work successful aging at work . [25] to review the literature on aging at work policies.
    keywords: age; aging; analysis; articles; discrimination; health; pension; policies; review; study; work; workers; workforce
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        item: #44 of 68
          id: cord-307915-mmw5s981
      author: Hudson, Janella
       title: Robotic Pet Use Among Community-Dwelling Older Adults
        date: 2020-08-13
       words: 7515
      flesch: 39
     summary: The primary purpose of this study was to explore the efficacy of robotic pets in alleviating loneliness for older adults. Robotic pets may be an effective solution for alleviating loneliness in older adults, especially among those who live alone, have fewer social connections, and live less active lifestyles.
    keywords: adults; benefit; companion; features; loneliness; participants; pet; pets; robots; study; use
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        item: #45 of 68
          id: cord-308271-zzepl3on
      author: Calderón-Larrañaga, Amaia
       title: COVID-19: risk accumulation among biologically and socially vulnerable older populations
        date: 2020-08-17
       words: 2537
      flesch: 39
     summary: Based on preliminary data from Sweden and other reports, in this paper we propose a conceptual framework whereby different factors related to biological and social vulnerability may explain the specific COVID-19 burden among older people. Up to one quarter of the deaths due COVID-19 have been in older people aged 70-79 years and up to two thirds in those over 80 years, regardless of the incidence of the disease or the completeness in the ascertainment of deaths across countries ( Table 1) .
    keywords: adults; care; covid-19; data; health; income; people
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        item: #46 of 68
          id: cord-308677-dr9a3ug0
      author: Hall, William J.
       title: Benefits of Intensive Care Unit Hospitalization for Patients Older than 90 Years
        date: 2020-06-27
       words: 1398
      flesch: 53
     summary: But the reality is, fundamental data on what benefit ICU care might have for older adults were not a paramount decision tool. There have been previous studies with perhaps lower statistical power that have documented mortality rates among older adults hospitalized in ICUs similar to those reported here, but Hass and colleagues 2 have added a decade of hospital experience for the entire country.
    keywords: icu; mortality; patients; years
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        item: #47 of 68
          id: cord-309267-ihc7h8ik
      author: Vervaecke, Deanna
       title: Caremongering and Assumptions of Need: The Spread of Compassionate Ageism During COVID-19
        date: 2020-09-12
       words: 4206
      flesch: 41
     summary: Paternalistic age stereotypes and assumptions of older adults competence that frame older people as dependent have homogenized older adults, cultivated the conditions of high risk A c c We begin by describing stereotype content theory and compassionate ageism and then explore how the oversimplification of COVID-19 risks for older adults has contributed to expressions of compassionate ageism.
    keywords: adults; ageism; caremongering; covid-19; pandemic
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        item: #48 of 68
          id: cord-310556-ebh59adi
      author: Flett, Gordon L.
       title: Aging and Feeling Valued Versus Expendable During the COVID-19 Pandemic and Beyond: a Review and Commentary of Why Mattering Is Fundamental to the Health and Well-Being of Older Adults
        date: 2020-06-15
       words: 14784
      flesch: 46
     summary: Suicide and Life-Threatening Behavior A phenomenological study of meaning in life in suicidal older adults Aging well in an upscale retirement community: the relationships among perceived stress, mattering, and wellness Manual for the Five Factor Wellness Inventory Interventions to address social connectedness and loneliness for older adults: a scoping review Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Outcomes of occupational self-efficacy in older workers The structure of personality capabilities Functional flexibility: a new conception of interpersonal flexibility Extending self-esteem theory and research: sociological and psychological currents Health benefits of volunteering in the Wisconsin Longitudinal Study The perception of depression in long-term care residents: a qualitative study using resident journals Mattering at the intersection of psychology, philosophy, and politics A geroscience perspective on COVID-19 mortality Family connectedness moderates the association between living along and suicide ideation in a clinical sample of adults 50 years and older The CES-D Scale: a self-report depression scale for research in the general population The link between functional limitations and depressive symptoms: the explanatory role of self-conceptions Understanding physical educators' perceptions of mattering: validating of the Perceived Mattering Questionnaire-Physical Education The role of context and the interpersonal experience of loneliness among older adult people in a residential care facility Self-concept and psychological well-being in adolescence Mattering: inferred significance and mental health among adolescents Happiness is everything, or is it? This article is about the need to matter among older people.
    keywords: adults; care; depression; et al; feeling; health; life; loneliness; mattering; need; pandemic; people; research; self; sense; social; study; suicide
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        item: #49 of 68
          id: cord-311757-qbk4aapf
      author: Dawes, Piers
       title: Challenges of the COVID‐19 pandemic for social gerontology in Australia
        date: 2020-09-23
       words: 1746
      flesch: 41
     summary: In the longer term, issues of mental health for older people, prevention, and | 3 resilience of health care and social support for older adults will grow in importance. Health services have changed practice to support older people with tele-services, though the effectiveness and uptake of these modes of delivery are not known at the population level.
    keywords: care; health; pandemic; people; research; term
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        item: #50 of 68
          id: cord-313218-4rbxdimf
      author: Narushima, Miya
       title: “Fiercely independent”: Experiences of aging in the right place of older women living alone with physical limitations
        date: 2020-09-09
       words: 7199
      flesch: 55
     summary: According to the 2015/2016 Canadian Community Health Survey, over one-third (35.4%) of people with home care needs did not have their needs met, especially among those with home support services for maintenance of daily living (Gilmour, 2018) . While aging in place has been a policy priority in rapidly greying Canada, a lack of complementary public supports poses challenges for many older adults and their family members.
    keywords: adults; aging; canada; care; health; home; housing; life; living; participants; place; support; women
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        item: #51 of 68
          id: cord-313413-qx6fo1x2
      author: Cipriano, Catia
       title: Metallothionein (I+II) confers, via c-myc, immune plasticity in oldest mice: model of partial hepatectomy/liver regeneration
        date: 2003-06-19
       words: 5749
      flesch: 49
     summary: Since MT also affects c-myc, the gene expression of c-myc declines from 48 h to days 7 and 15 after pHx in young and very old mice, but remains constantly high in old pHx mice for the same days. This circumstance leads to the appearance of tumours in the long run in old pHx mice and survival times that are shorter than old sham controls.
    keywords: immune; liver; mice; phx; regeneration; sham; young; zinc
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        item: #52 of 68
          id: cord-317519-yhzv2yjs
      author: Barzilai, Nir
       title: Geroscience in the Age of COVID-19
        date: 2020-07-23
       words: 2595
      flesch: 31
     summary: Healthy aging: the ultimate preventative medicine Immunosenescence: emerging challenges for an ageing population Benefits of metformin in attenuating the hallmarks of aging Metformin as a tool to target aging Metformin: historical overview Metformin improves in vivo and in vitro B cell function in individuals with obesity and Type-2 Diabetes Metformin treatment was associated with decreased mortality in COVID-19 patients with diabetes in a retrospective analysis Observational study of metformin and risk of mortality in patients hospitalized with Covid-19 mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells mTOR inhibition improves immune function in the elderly TORC1 inhibition enhances immune function and reduces infections in the elderly A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: immunological, physical performance, and cognitive effects Rapamycin for longevity: opinion article Innate and adaptive immunity in aging and longevity: the foundation of resilience Quantification of biological aging in young adults Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Renin-Angiotensin-Aldosterone system inhibitors in patients with Covid-19 Strategies and challenges in clinical trials targeting human aging Recognizing degenerative aging as a treatable medical condition: methodology and policy Measuring biological aging in humans: a quest The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population Aging health and R&D for healthy longevity must be included into the WHO Work Program Strategies must be developed for periodic frailty assessment with continuous longitudinal follow-up of older persons which may reveal not only global determinants that are conserved, but also local singularities involved in differential aging health around the world.
    keywords: age; aging; covid-19; geroscience; health; metformin
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        item: #53 of 68
          id: cord-318977-4ng6gxpv
      author: Zittoun, Tania
       title: The relevance of a sociocultural perspective for understanding learning and development in older age
        date: 2020-09-26
       words: 5658
      flesch: 32
     summary: First, having lived longer lives, older people are more likely to have lived through more spheres of experiences, and more reconfiguration of spheres of experiences than younger people: many family or friend-related experiences, numerous professional situations, situations related to social life, events related to leisure activities, diverse cultural events. At another extreme, older people may have developed negative representations of institutions and the social world, which, they feel, have closed down their opportunities to participate; excluded from social life, with spheres of experience that may be less satisfying, the may have very little occasions to produce meaningful activities and therefore to develop imaginations of their future.
    keywords: ageing; conditions; development; experience; future; life; lives; people; psychology; zittoun
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        item: #54 of 68
          id: cord-324635-27q3nxte
      author: Bouza, Emilio
       title: The situation of infection in the elderly in Spain: a multidisciplinary opinion document
        date: 2020-09-08
       words: 15951
      flesch: 42
     summary: In a study conducted in China, in 6 sentinel hospitals, it was observed that 31.64% of elderly patients with respiratory infection had a viral aetiology (41.8% among extra-hospital infections and 25.7% among fecting the elderly vary depending on the clinical environment (home, nursing home, hospital) and the functional status of the patient. It is interesting to note the safety of using the same therapeutic options in elderly patients, including faecal microbiota transplantation [29, 30] .
    keywords: age; care; cases; community; control; data; diseases; emergency; health; healthcare; homes; hospital; infections; information; life; nursing; patients; people; pneumonia; population; prevalence; prevention; problems; spain; spanish; study; term; tract; treatment; use; years
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        item: #55 of 68
          id: cord-325026-k514rh8g
      author: Parlapani, Eleni
       title: Intolerance of Uncertainty and Loneliness in Older Adults During the COVID-19 Pandemic
        date: 2020-08-19
       words: 7952
      flesch: 42
     summary: Achieving certainty about the structure of intolerance of uncertainty in a treatment-seeking sample with anxiety and depression Fearing the unknown: A short version of the Intolerance of Uncertainty Scale Into the unknown: A review and synthesis of contemporary models involving uncertainty Experimental manipulation of intolerance of uncertainty: A study of a theoretical model of worry The fear of COVID-19 scale: Development and initial validation Fear of the coronavirus (COVID-19): Predictors in an online study conducted in Considerations relating to social distancing measures in response to COVID-19 -second update Epidemics, quarantine and mental health The emotional path to action: Empathy promotes physical distancing during the COVID-19 pandemic COVID-19 and the consequences of isolating the elderly Loneliness and health in older adults: a mini-review and synthesis Loneliness: The Experience of Emotional and Social Isolation A 6-item scale for overall, emotional, and social loneliness: Confirmatory tests on survey data Older adult loneliness: Myths and realities Anxiety, Depression, Loneliness and Social Network in the Elderly: Longitudinal Associations from The Irish Longitudinal Study on Ageing (TILDA) Similarly, the COVID-19 pandemic affected older people in many different aspects.
    keywords: adults; age; anxiety; care; covid-19; health; item; loneliness; pandemic; people; scale; study; symptoms; uncertainty
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        item: #56 of 68
          id: cord-329344-06uk5sjp
      author: Neumann-Podczaska, Agnieszka
       title: COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review
        date: 2020-07-23
       words: 5928
      flesch: 40
     summary: Description: Ground Glass Opacities (GGO) was the most commonly reported observation in radiological imaging of older COVID-19 patients. 10-18, 24-26, 28 Besides a risk for secondary infection or ARDS, older COVID-19 patients are prone to renal injury over the course of the disease.
    keywords: clinical; covid-19; data; disease; findings; patients; population; review; studies; study
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        item: #57 of 68
          id: cord-331378-3nqn48z7
      author: Wand, Anne Pamela Frances
       title: COVID-19: the implications for suicide in older adults
        date: 2020-04-30
       words: 3949
      flesch: 39
     summary: Perspectives from SARS to Ebola The psychological impact of quarantine and how to reduce it: rapid review of the evidence Exploring the use of telephone helpline pertaining to older adult suicide prevention: Older people have been specifically advised to stay home given their vulnerability to COVID-19 and to reduce the burden on health services by limiting the spread of the illness.
    keywords: covid-19; et al; health; pandemic; people; services; suicide
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        item: #58 of 68
          id: cord-332579-7950xjmv
      author: Aravena, J. M.
       title: 'Drawing on Wisdom to Cope with Adversity:' A Systematic Review Protocol of Older Adults' Mental and Psychosocial Health During Acute Respiratory Disease Propagated-Type Epidemics and Pandemics (COVID-19, SARS-CoV, MERS, and Influenza).
        date: 2020-06-07
       words: 5013
      flesch: 37
     summary: In this context, and considering the increasing number of COVID-19 related articles, a systematic review targeted to older people mental health considering a full-range of neuropsychiatric, psychiatric, psychosocial, and wellbeing parameters associated with the infection or the contextual impacts related to acute respiratory disease propagated-type epidemics and pandemics, contrasting the results among groups seems pertinent and necessary to fully understand the response and experiences of older adults and other age groups in the context of pandemics. . 34, 35 Studies will be divided into two main categories for its analysis: 1) studies describing the direct effect of virus infection on mental health outcomes, and 2) studies illustrating mental health impact associated with the contextual situation of the epidemic or pandemic (e.g. quarantines, social distancing, isolation).
    keywords: adults; covid-19; data; groups; health; pandemics; psychosocial; studies; study; type
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        item: #59 of 68
          id: cord-332652-wm9krxve
      author: Koslik, Hayley J.
       title: Prevalence and correlates of obstructive lung disease among people who inject drugs, San Diego, California
        date: 2020-07-02
       words: 4523
      flesch: 46
     summary: Black race (AOR = 2.66, 95%CI: 1.37, 5.17), pack-years smoked (AOR = 1.06/5 years, 95%CI: 1.01, 1.12), and duration of injection drug use (AOR = 1.13, 95%CI: 1.01, 1.27) were independently associated with OLD after controlling for age. In addition, OLD prevalence increased with greater duration of injection drug use, suggesting a link between cumulative exposure to injected insoluble particles and OLD.
    keywords: disease; drug; prevalence; pwid; study; use
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        item: #60 of 68
          id: cord-332918-6kmbaswt
      author: Dwolatzky, Tzvi
       title: If Not Now, When? the Role of Geriatric Leadership as Covid-19 Brings the World to Its Knees
        date: 2020-05-15
       words: 2331
      flesch: 53
     summary: She recognized that older people had different needs, and emphasized a multidisciplinary comprehensive rehabilitative approach that forms the basis of the profession today (4). And now, with a viral pandemic sweeping across the globe, geriatricians are actively involved in the clinical care of vast numbers of older people in the community and in hospital settings.
    keywords: age; care; covid-19; geriatricians; health; people
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        item: #61 of 68
          id: cord-333959-8ermzrmr
      author: Gao, Zan
       title: Virtual Reality Exercise as a Coping Strategy for Health and Wellness Promotion in Older Adults during the COVID-19 Pandemic
        date: 2020-06-25
       words: 5573
      flesch: 39
     summary: In addition, there is a need for more research investigating the effectiveness of VR exercise programs on older adults' weight loss, as VR exercise has only recently been applied as a means for weight control. These findings support the effectiveness of VR exercise interventions in reducing fall rates and improving balance in older adults.
    keywords: adults; balance; exercise; health; intervention; motor; outcomes; reality; study
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        item: #62 of 68
          id: cord-338049-en9ktl4s
      author: Naarding, P.
       title: COVID-19: clinical challenges in Dutch Geriatric Psychiatry
        date: 2020-05-27
       words: 1492
      flesch: 51
     summary: Many aspects of mental health care facilities make older patients with psychiatric disorders susceptible to the rapid spread of COVID-19 Case B -In the long-stay ward for older patients, Mrs. B, an 83-year old woman, was admitted 7 months ago after the death of her husband.
    keywords: care; case; covid-19; health
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        item: #63 of 68
          id: cord-338332-msjtncek
      author: Sharifian, Neika
       title: Social Relationships and Adaptation in Later Life
        date: 2020-09-18
       words: 17299
      flesch: 31
     summary: Individuals engage in social relationships across the life course and it is important to note that age-related changes in the structure, function and quality of social relations occur in later life. Not the quantity but the quality of social interactions is protective up to 15 years later Social relations: an examination of social networks, social support, and sense of control Social networks in adult life and a preliminary examination of the convoy model The convoy model: explaining social relations from a multidisciplinary perspective The effect of social relations with children on the education-health link in men and women aged 40 and over Social relations and technology: continuity, context, and change Convoys of social relations: cohort similarities and differences over 25 years Social relations and mortality: a more nuanced approach Parental child-rearing strategies influence self-regulation, socio-emotional adjustment, and psychopathology in early adulthood: evidence from a retrospective cohort study On the incomplete architecture of human ontogeny: selection, optimization, and compensation as foundation of developmental theory Handbook of Child Psychology:
    keywords: adults; age; et al; family; friends; health; life; loneliness; network; outcomes; quality; relations; relationships; research; social; study; support; use
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        item: #64 of 68
          id: cord-339292-mhbwjwrg
      author: Aubertin-Leheudre, M.
       title: THE IMPORTANCE OF PHYSICAL ACTIVITY TO CARE FOR FRAIL OLDER ADULTS DURING THE COVID-19 PANDEMIC
        date: 2020-04-30
       words: 961
      flesch: 40
     summary: The death rate is estimated at 5%, with older adults making up 38 the vast majority of cases (>80%). Thus, although COVID-19 restrictions aim to protect older adults, such social and 58 physical distancing is also likely to negatively impact the physical and mental health of older 59 Furthermore, long-term care residents are characterized by high prevalence of multimorbidity, 61 prescription drug use and dependency in activities of daily living.
    keywords: activity; adults; covid-19
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        item: #65 of 68
          id: cord-340117-14bmab0n
      author: Navarrete‐Reyes, Ana Patricia
       title: Staying in a Burning House: Perks and Perils of a Hotline in the Times of COVID‐19
        date: 2020-05-05
       words: 1022
      flesch: 51
     summary: In 10 days, I have received 64 calls and text messages about and from older adults. A second group is composed of older adults and their loving family/friends/neighbors wondering what they can do to reduce their risk of infection.
    keywords: covid-19; group; hotline; mexico
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        item: #66 of 68
          id: cord-344818-ms2edk3w
      author: Chu, Charlene H.
       title: Competing Crises: COVID‐19 Countermeasures and Social Isolation among Older Adults in Long Term Care
        date: 2020-07-09
       words: 2022
      flesch: 44
     summary: key: cord-344818-ms2edk3w authors: Chu, Charlene H.; Donato‐Woodger, Simon; Dainton, Christopher J. title: Competing Crises: COVID‐19 Countermeasures and Social Isolation among Older Adults in Long Term Care date: 2020-07-09 journal: J Adv Nurs DOI: 10.1111/jan.14467 sha: doc_id: 344818 cord_uid: ms2edk3w While debate over the appropriate scope and goals of COVID‐19 lockdowns has raged, all public health agencies have been clear on one matter: older adults have the highest rates of mortality (Comas‐Herrera et al., 2020) and should be isolated (Public Health Agency of Canada, 2020).
    keywords: adults; care; covid-19; isolation; ltc; residents
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        item: #67 of 68
          id: cord-350907-lazslqn0
      author: Isik, Ahmet Turan
       title: Covid-19 Infection in Older Adults: A Geriatrician’s Perspective
        date: 2020-07-06
       words: 1534
      flesch: 41
     summary: 1, 2 Regarding the severe course of the disease in the elderly, I would like to draw attention to some issues related to the diagnosis of Covid-19 infections in older patients. 14 Considering that this period is 2.5 days in Covid-19 patients who do not need intensive care and are younger, the fact that dyspnea occurs approximately 6.5 days after the first symptom 14 is also striking in terms of the importance of atypical presentations.
    keywords: covid-19; disease; fever; patients
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        item: #68 of 68
          id: cord-354105-lgkfnmcm
      author: Office, Emma E.
       title: Reducing Social Isolation of Seniors during COVID-19 through Medical Student Telephone Contact
        date: 2020-06-05
       words: 1660
      flesch: 45
     summary: key: cord-354105-lgkfnmcm authors: Office, Emma E.; Rodenstein, Marissa S.; Merchant, Tazim S.; Pendergrast, Tricia Rae; Lindquist, Lee A. title: Reducing Social Isolation of Seniors during COVID-19 through Medical Student Telephone Contact date: 2020-06-05 journal: J Am Med Dir Assoc DOI: 10.1016/j.jamda.2020.06.003 sha: doc_id: 354105 cord_uid: lgkfnmcm Abstract Social isolation has been associated with many adverse health outcomes in older adults. We describe a phone call outreach program in which health care professional student volunteers phoned older adults, living in long-term care facilities and the community, at risk of social isolation during the COVID-19 pandemic.
    keywords: adults; health; isolation; social
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