# bib

id: cord-279863-5kxgu4t9
author: Oem, Jae-Ku
title: Phylogenetic analysis of bovine astrovirus in Korean cattle
date: 2013-11-23
extension: .txt
mime: text/plain
words: 1633
sentence: 94
flesch: 62
cache: cache/cord-279863-5kxgu4t9.txt
txt: txt/cord-279863-5kxgu4t9.txt
summary:
  Nine of 115 fecal samples from Korean cattle were positive for BAstV and all of the BAstVs were related to diarrhea. Nonambulatory cattle which are commonly referred to as ''downer'' cattle are unable to stand or walk.


id: cord-339178-d6f6a5ds
author: Pensaert, M. B.
title: A new coronavirus-like particle associated with diarrhea in swine
date: 1978
extension: .txt
mime: text/plain
words: 1750
sentence: 79
flesch: 52
cache: cache/cord-339178-d6f6a5ds.txt
txt: txt/cord-339178-d6f6a5ds.txt
summary:
  Diarrhea was reproduced in experimental pigs with one of the isolates, designated CV777, which was found to be distinct from the 2 known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus. Diarrhea was reproduced in experimental pigs with one of the isolates, designated CV777, which was found to be distinct from the 2 known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.


id: cord-339924-tsmnkuhw
author: Jung, Kwonil
title: Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs
date: 2014-04-17
extension: .txt
mime: text/plain
words: 1865
sentence: 65
flesch: 41
cache: cache/cord-339924-tsmnkuhw.txt
txt: txt/cord-339924-tsmnkuhw.txt
summary:
  Six 10-to 35-day-old pigs were randomly assigned to a PEDV-infected group (pigs 1-5) or a negative control group (pig 6). Pigs 1-3 and 5 were inoculated orally and/or intranasally with 6.3-9.0 log 10 genomic equivalents (GE) of PEDV strain PC21A; pig 4 was exposed to the virus by indirect contact with inoculated pig 3.


id: cord-285585-tigj7fhc
author: Cleveland, Christopher A.
title: Survey for selected pathogens in wild pigs (Sus scrofa) from Guam, Marianna Islands, USA
date: 2017-05-03
extension: .txt
mime: text/plain
words: 2945
sentence: 114
flesch: 44
cache: cache/cord-285585-tigj7fhc.txt
txt: txt/cord-285585-tigj7fhc.txt
summary:
  key: cord-285585-tigj7fhc authors: Cleveland, Christopher A.; DeNicola, Anthony; Dubey, J.P.; Hill, Dolores E.; Berghaus, Roy D.; Yabsley, Michael J. title: Survey for selected pathogens in wild pigs (Sus scrofa) from Guam, Marianna Islands, USA date: 2017-05-03 journal: Vet Microbiol DOI: 10.1016/j.vetmic.2017.05.001 sha: doc_id: 285585 cord_uid: tigj7fhc Pigs (Sus scrofa) were introduced to Guam in the 1600’s and are now present in high densities throughout the island. Wild pigs are reservoirs for pathogens of concern to domestic animals and humans.


id: cord-281679-xmbnpawj
author: Meekins, David A.
title: Susceptibility of swine cells and domestic pigs to SARS-CoV-2
date: 2020-08-16
extension: .txt
mime: text/plain
words: 3412
sentence: 142
flesch: 40
cache: cache/cord-281679-xmbnpawj.txt
txt: txt/cord-281679-xmbnpawj.txt
summary:
  In the current study, we determined the ability of SARS-CoV-2 to (i) replicate in porcine cell lines, (ii) establish infection in domestic pigs via experimental oral/intranasal/intratracheal inoculation, and (iii) transmit to co-housed naive sentinel pigs. SARS-CoV-2 is a member of the Betacoronavirus genus that includes the pathogenic human viruses SARS-CoV-1 and MERS-CoV


id: cord-009820-fi54s0x7
author: Andries, K.
date: 2010-05-13
extension: .txt
mime: text/plain
words: 3847
sentence: 188
flesch: 49
cache: cache/cord-009820-fi54s0x7.txt
txt: txt/cord-009820-fi54s0x7.txt
title:
  Pathogenicity of Hemagglutinating Encephalomyelitis (Vomiting and Wasting Disease) Virus of Pigs, using Different Routes of Inoculation

summary:
  The inability to find the virus in the cerebral cortex of ON inoculated pigs may indicate that the present isolate has little or no affinity for this part of the central nervous system. du dCpCrissement des porcelets (coronalike virus) Lesions induced by hemagglutinating enccphalomyelitis virus strain 67 N in pigs Vomiting and wasting disease in piglets A hemagglutinating virus producing encephalomyelitis in baby pigs Characteristics of a coronavirus (strain 67 N) of pigs Experimentally induced infection of newborn pigs with hemagglutinating encephalomyelitis virus strain 67 N Pathogenicity of field isolants of hemagglutinating encephalomyelitis virus from neonatal pigs Characteristics of a coronavirus causing vomition and wasting in pigs The size and morphology of TGE and vomiting and wasting disease viruses of pifs A viral encepha omyelitis of pigs.


id: cord-348522-r7ev9br6
author: Englund, Stina
title: The occurrence of Chlamydia spp. in pigs with and without clinical disease
date: 2012-01-26
extension: .txt
mime: text/plain
words: 3893
sentence: 184
flesch: 50
cache: cache/cord-348522-r7ev9br6.txt
txt: txt/cord-348522-r7ev9br6.txt
summary:
  Ferkel-Darm Intestinal lesions caused by two swine chlamydial isolates in gnotobiotic pigs Experimental enteric infection of gnotobiotic piglets with Chlamydia suis strain S45 Intestinal lesions caused by a strain of Chlamydia suis in weanling pigs infected at 21 days of age Small intestinal Chlamydia infection in piglets Intensively kept pigs pre-disposed to chlamydial associated conjunctivitis Conjunctivitis caused by a swine Chlamydia trachomatis-like organism in gnotobiotic pigs Chlamydial zoonoses. in pig herds.


id: cord-302155-hksmt48i
author: McLean, Rebecca K.
title: Vaccine Development for Nipah Virus Infection in Pigs
date: 2019-02-04
extension: .txt
mime: text/plain
words: 4169
sentence: 145
flesch: 36
cache: cache/cord-302155-hksmt48i.txt
txt: txt/cord-302155-hksmt48i.txt
summary:
  Final rule Can Ebola virus vaccines have universal immune correlates of protection? The sporadic nature of NiV outbreaks means that the commercial development of NiV vaccines for use in pigs (other livestock or humans) is limited and animal health companies are of the opinion that NiV vaccines will have limited marketability.


id: cord-257922-tbkitz7m
author: Sookhoo, Jamie R. V.
date: 2017-05-18
extension: .txt
mime: text/plain
words: 4445
sentence: 168
flesch: 51
cache: cache/cord-257922-tbkitz7m.txt
txt: txt/cord-257922-tbkitz7m.txt
title:
  Seroprevalence of economically important viral pathogens in swine populations of Trinidad and Tobago, West Indies

summary:
  Sampling was conducted on pig farms throughout T&T. Training of workers on pig farms to recognize influenza-like symptoms in humans and pigs should also be carried out (Adeola et al. 2015) .


id: cord-261925-nsq837z1
author: Denner, Joachim
title: Preventing transfer of infectious agents
date: 2015-08-24
extension: .txt
mime: text/plain
words: 4311
sentence: 186
flesch: 34
cache: cache/cord-261925-nsq837z1.txt
txt: txt/cord-261925-nsq837z1.txt
summary:
  key: cord-261925-nsq837z1 authors: Denner, Joachim; Mueller, Nicolas J. title: Preventing transfer of infectious agents date: 2015-08-24 journal: Int J Surg DOI: 10.1016/j.ijsu.2015.08.032 sha: doc_id: 261925 cord_uid: nsq837z1 Xenotransplantation using pig cells, tissues and organs may be associated with the transfer of porcine infectious agents, which may infect the human recipient and in the worst case induce a disease (zoonosis). Xenotransplantation using pig cells, tissues and organs has to overcome three hurdles before being applied in the clinic for the treatment of organ failure: immunological rejection, physiological incompatibility and transfer of infectious agents.


id: cord-273705-0oyzg5tq
author: Duffy, Mark A
date: 2018-08-29
extension: .txt
mime: text/plain
words: 4636
sentence: 164
flesch: 51
cache: cache/cord-273705-0oyzg5tq.txt
txt: txt/cord-273705-0oyzg5tq.txt
title:
  Impact of dietary spray-dried bovine plasma addition on pigs infected with porcine epidemic diarrhea virus

summary:
  The average fecal PEDV RNA shedding time was 7.2 ± 1.0 d for the PEDV–BovSDP group and 9.3 ± 1.1 d for the PEDV group with an overall time to clearance of PEDV shedding of 11 d for PEDV–BovSDP pigs and at least 14 d for PEDV pigs, which was not different (P = 0.215). Overall, there were numerical differences among groups for the ADG: NEG pigs had the highest ADG, and PEDV pigs had the lowest ADG; however, the differences were not significant.


id: cord-297669-22fctxk4
author: Proudfoot, Chris
title: Genome editing for disease resistance in pigs and chickens
date: 2019-06-25
extension: .txt
mime: text/plain
words: 4555
sentence: 185
flesch: 38
cache: cache/cord-297669-22fctxk4.txt
txt: txt/cord-297669-22fctxk4.txt
summary:
  CD163 consists of nine globular domains, organized like beads on a string, with domain 5 determined to mediate the key-lock interaction allowing viral entry into pig cells (Van Gorp et al., 2010) . Technical improvements in the generation of genome editing animals will undoubtedly reduce the cost implications of this technology.


id: cord-277487-jgbjxgh1
author: Graham, Simon P.
date: 2020-06-20
extension: .txt
mime: text/plain
words: 5084
sentence: 168
flesch: 44
cache: cache/cord-277487-jgbjxgh1.txt
txt: txt/cord-277487-jgbjxgh1.txt
title:
  Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

summary:
  For analysis of T cell responses in pigs, overlapping 16mer peptides offset by 4 residues based on the predicted amino acid sequence of the entire S protein from SARS-CoV-2 Wuhan-Hu-1 isolate (NCBI Reference Sequence: NC_045512.2) were designed and synthesised (Mimotopes, Melbourne, Australia) and reconstituted in sterile 40% acetonitrile (Sigma-Aldrich) at a concentration of 3 mg/mL. Three pools of synthetic peptides representing residues 1-331 (Pool 1), 332-748 (Pool 2) and 749-1273 (Pool 3) were prepared for use to stimulate T cells in IFN-γ ELISpot and intracellular cytokine staining (ICS) assays. We show here that T cell responses are higher in pigs that received a prime-boost vaccination when compared to prime only at day 42, whilst comparing responses 14 days after last immunisation demonstrates the prime-boost regimen trended toward a higher response.


id: cord-288101-pij16jaa
author: Li, Jun-Yu
title: Proteomic analysis of the response of porcine adrenal gland to heat stress
date: 2019-02-28
extension: .txt
mime: text/plain
words: 5160
sentence: 182
flesch: 36
cache: cache/cord-288101-pij16jaa.txt
txt: txt/cord-288101-pij16jaa.txt
summary:
  This conclusion follows directly from data suggesting that heat stress reduces the expression of heat shock proteins, handicapping their ability to induce a protective immune response when immunocytes are confronted with foreign entities. Among these 226 DEPs, tubulin and heat shock protein (HSP) such as HSP70, HSP60, HSP27, and Histone H2A might be involved in the regulation of heat stress.


id: cord-003447-kbpvt5on
author: Atherstone, C.
title: Analysis of pig trading networks and practices in Uganda
date: 2018-08-02
extension: .txt
mime: text/plain
words: 5672
sentence: 219
flesch: 51
cache: cache/cord-003447-kbpvt5on.txt
txt: txt/cord-003447-kbpvt5on.txt
summary:
  We purposely interviewed pig traders during periods when demand for pork was historically high and theorized that this would mean that more pig traders would be bringing pigs in for processing. This study interviewed pig traders operating at Uganda’s only registered pork abattoir to describe their characteristics, business practices, biosecurity practices, and pig health management and reporting practices.


id: cord-282849-ve8krq78
author: Stebler, Rosa
date: 2019-09-20
extension: .txt
mime: text/plain
words: 5938
sentence: 246
flesch: 43
cache: cache/cord-282849-ve8krq78.txt
txt: txt/cord-282849-ve8krq78.txt
title:
  Extrapolating Antibiotic Sales to Number of Treated Animals: Treatments in Pigs and Calves in Switzerland, 2011–2015

summary:
  Sales of veterinary antimicrobial agents in 30 European Joint FAO/OIE/WHO Expert Workshop on Non-Human Antimicrobial Usage and Antimicrobial Resistance: Scientific assessment The antimicrobial resistome in relation to antimicrobial use and biosecurity in pig farming, a metagenome-wide association study in nine European countries Association between antimicrobial usage, biosecurity measures as well as farm performance in German farrow-to-finish farms Factors associated with high antimicrobial use in young calves on Dutch dairy farms: a casecontrol study Antimicrobial resistance: monitoring the quantities of antimicrobials used in animal husbandry Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands in 2017 Trends in the Sales of Veterinary Antimicrobial Agents in Nine European Countries Annual report on antimicrobial agents intended for use in animals Canadian Antimicrobial Resistance Surveillance System Comparison of the sales of veterinary antibacterial agents between 10 European countries ANSES. Antimicrobial sales data are defined as the minimal standard for monitoring programs by the World Organization for Animal Health [Office International des Epizooties, OIE; (10) ].


id: cord-308767-trwa5grl
author: Costa Vallés, Cristina
title: Transgenic Organs and Xenotransplants
date: 2012-03-20
extension: .txt
mime: text/plain
words: 6398
sentence: 239
flesch: 39
cache: cache/cord-308767-trwa5grl.txt
txt: txt/cord-308767-trwa5grl.txt
summary:
  This led research to focus on WKH SURGXFWLRQ RI SLJV ZLWK JHQHWLF PRGL¿FDWLRQV WKDW ZRXOG UHGXFH WKH UHDFWLYLW\ RI WKH organs to xenoantibodies present in human serum. Xenotransplantation, which is the transplant of cells, tissues or organs from other species, became the focus of attention in the nineteen-nineties as a solution to the lack of RUJDQV DQG WLVVXHV IRU WUDQVSODQWDWLRQ $W WKDW SRLQW DIWHU WKH SURGXFWLRQ RI WKH ¿UVW WUDQVJHQLF pigs, this species was selected as the best source of organs and xenogeneic tissues.


id: cord-296441-682uop9z
author: Montoya, María
title: Expression Dynamics of Innate Immunity in Influenza Virus-Infected Swine
date: 2017-04-21
extension: .txt
mime: text/plain
words: 6333
sentence: 266
flesch: 48
cache: cache/cord-296441-682uop9z.txt
txt: txt/cord-296441-682uop9z.txt
summary:
  Swine IV infection induced interferon (IFN)-alpha and interleukin-6 responses in bronchoalveolar fluids (BALF) at day 3 post infection, as opposed to the other non-swine-adapted virus strains. Swine IV infection induced interferon (IFN)-alpha and interleukin-6 responses in bronchoalveolar fluids (BALF) at day 3 post infection, as opposed to the other nonswine-adapted virus strains.


id: cord-332049-geh9aaf5
author: Wagner, Judith
date: 2010-01-20
extension: .txt
mime: text/plain
words: 6437
sentence: 276
flesch: 45
cache: cache/cord-332049-geh9aaf5.txt
txt: txt/cord-332049-geh9aaf5.txt
title:
  Respiratory function and pulmonary lesions in pigs infected with porcine reproductive and respiratory syndrome virus

summary:
  # Indicates significant differences between PRRSV challenged pigs and controls (W-test, P 6 0.05). # Indicates significant differences between PRRSV challenged pigs and controls (Wtest, P 6 0.05).


id: cord-002272-c7f1l13s
author: Sauter, Kristin A.
date: 2016-07-21
extension: .txt
mime: text/plain
words: 6673
sentence: 276
flesch: 46
cache: cache/cord-002272-c7f1l13s.txt
txt: txt/cord-002272-c7f1l13s.txt
title:
  Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs

summary:
  To explore the role of CSF1 in steady-state control of monocyte production and differentiation and tissue repair, we previously developed a bioactive protein with a longer half-life in circulation by fusing pig CSF1 with the Fc region of pig IgG1a. We fused pig CSF1, which is equally active in all mammalian species tested (20) , with the Fc region of pig IgG1a (CSF1-Fc) (21) .


id: cord-351834-9pclxek0
author: Cohen, Liza Miriam
title: A descriptive study of acute outbreaks of respiratory disease in Norwegian fattening pig herds
date: 2020-06-24
extension: .txt
mime: text/plain
words: 6847
sentence: 334
flesch: 45
cache: cache/cord-351834-9pclxek0.txt
txt: txt/cord-351834-9pclxek0.txt
summary:
  Regulation on swine and poultry production Annual statistical report The successful eradication of Mycoplasma hyopneumoniae from Norwegian pig herds -10 years later. The main objective of this study was to investigate clinical outbreaks of acute respiratory disease in Norwegian fattening pig herds, using a group of non-outbreak herds to compare diagnostic procedures.


id: cord-281309-c9y7m5do
author: Guo, Baoqing
date: 2013-01-20
extension: .txt
mime: text/plain
words: 7974
sentence: 233
flesch: 37
cache: cache/cord-281309-c9y7m5do.txt
txt: txt/cord-281309-c9y7m5do.txt
title:
  Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virus

summary:
  Mean interstitial pneumonia lesions were 3.33, 3.75, and 2.00 for Chinese PRRSV challenge group (Group 2), contact Chinese PRRSV pigs (Group 3) and VR-2332 challenge (Group 4), respectively (Fig. 3B ). Lesions were significantly (P¼0.0002) more severe in the Chinese PRRSV challenge group (Group 2) and contact Chinese PRRSV pigs (Group 3) as compared to the VR-2332 challenge (Group 4).


id: cord-013174-whg64w0w
author: Bhatta, Tarka Raj
date: 2020-09-10
extension: .txt
mime: text/plain
words: 8222
sentence: 318
flesch: 53
cache: cache/cord-013174-whg64w0w.txt
txt: txt/cord-013174-whg64w0w.txt
title:
  Infection Dynamics of Swine Influenza Virus in a Danish Pig Herd Reveals Recurrent Infections with Different Variants of the H1N2 Swine Influenza A Virus Subtype

summary:
  A virus discovered from pigs in Germany Molecular epidemiology and evolution of influenza viruses circulating within European swine between Reassortant pandemic (H1N1) 2009 virus in pigs Triple-reassortant influenza A virus with H3 of human seasonal origin, NA of swine origin, and internal A (H1N1) pandemic 2009 genes is established in Danish pigs Genetic and biological characterisation of an avian-like H1N2 swine influenza virus generated by reassortment of circulating avian-like H1N1 and H3N2 subtypes in Denmark Why are RNA virus mutation rates so damn high? Evasion of influenza A viruses from innate and adaptive immune responses Substantial Antigenic Drift in the Hemagglutinin Protein of Swine Influenza A Viruses Molecular basis of the structure and function of H1 hemagglutinin of influenza virus Structural basis of influenza virus neutralization Vaccination potential of B and T epitope-enriched NP and M2 against influenza A viruses from different clades and hosts Cross-reactive human B cell and T cell epitopes between influenza A and B viruses Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population Glycosylation of hemagglutinin and neuraminidase of influenza a virus as signature for ecological spillover and adaptation among influenza reservoirs Structural Development in Danish Pig Production StatPearls Dual infections of feeder pigs with porcine reproductive and respiratory syndrome virus followed by porcine respiratory coronavirus or swine influenza virus: A clinical and virological study Interaction between Mycoplasma hyopneumoniae and swine influenza virus Swine influenza viruses: A North American perspective Development of a high-throughput real-time PCR system for detection of enzootic pathogens in pigs Raised without antibiotics Monitoring of Influenza A Virus in Pig Final Development and evaluation of a one-step real-time RT-PCR assay for universal detection of influenza A viruses from avian and mammal species Limited impact of influenza A virus vaccination of piglets in an enzootic infected sow herd Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses MUSCLE: A viruses The biology of influenza viruses


id: cord-266199-smlq11y9
author: Dhakal, Santosh
title: Nanoparticle-based vaccine development and evaluation against viral infections in pigs
date: 2019-11-06
extension: .txt
mime: text/plain
words: 7654
sentence: 319
flesch: 32
cache: cache/cord-266199-smlq11y9.txt
txt: txt/cord-266199-smlq11y9.txt
summary:
  potential and limitations Respiratory nanoparticle-based vaccines and challenges associated with animal models and translation Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice Poly(anhydride) nanoparticles act as active Th1 adjuvants through Toll-like receptor exploitation Liposome-based adjuvants for subunit vaccines: formulation strategies for subunit antigens and immunostimulators Vaccine delivery using nanoparticles Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles Enhancement of immune responses by co-delivery of a CpG oligodeoxynucleotide and tetanus toxoid in biodegradable nanospheres Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity M-cell targeted biodegradable PLGA nanoparticles for oral immunization against hepatitis B Dendritic cell targeted chitosan nanoparticles for nasal DNA immunization against SARS CoV nucleocapsid protein Rapid endo-lysosomal escape of poly(dl-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery Enhanced and prolonged crosspresentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles Cytotoxic T cell vaccination with PLGA microspheres interferes with influenza A virus replication in the lung and suppresses the infectious disease Entrapment of H1N1 influenza virus derived conserved peptides in PLGA nanoparticles enhances T cell response and vaccine efficacy in pigs Biodegradable nanoparticle delivery of inactivated swine influenza virus vaccine provides heterologous cell-mediated immune response in pigs Induction of potent antigen-specific cytotoxic T cell response by PLGA-nanoparticles containing antigen and TLR agonist Polyanhydride nanovaccine against swine influenza virus in pigs Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development Virus-like particle engineering: from rational design to versatile applications Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages Major findings and recent advances in virus-like particle (VLP)-based vaccines Development of a porcine reproductive and respiratory Research efforts are ongoing to develop porcine viral vaccines using NPs-based technologies.


id: cord-325433-a2fynm75
author: Riggs, Shannon M.
title: CHAPTER 17 GUINEA PIGS
date: 2009-12-31
extension: .txt
mime: text/plain
words: 8877
sentence: 479
flesch: 49
cache: cache/cord-325433-a2fynm75.txt
txt: txt/cord-325433-a2fynm75.txt
summary:
  In the wild, guinea pigs live in small groups and, therefore, are often more comfortable in the presence of other guinea pigs when maintained as companion animals. This chapter deals with the health and medical care issues of guinea pigs.


id: cord-302306-fudeixy2
author: Xu, Kui
date: 2020-09-02
extension: .txt
mime: text/plain
words: 9099
sentence: 327
flesch: 48
cache: cache/cord-302306-fudeixy2.txt
txt: txt/cord-302306-fudeixy2.txt
title:
  CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance

summary:
  In addition, with the exception of meat color score and iron content, no differences in the production performance, reproductive performance, or pork nutrient content were observed between DKO pigs and WT pigs. We used flow cytometry and western blotting for CD163, immunohistochemistry (IHC) and western blotting for pAPN, and confirmed that expression of both proteins was undetectable in DKO pigs but detectable in WT pigs of the same age and breed ( Figure 1E -G).


id: cord-260840-tudl9k1g
author: Opriessnig, Tanja
date: 2012-07-06
extension: .txt
mime: text/plain
words: 9521
sentence: 318
flesch: 46
cache: cache/cord-260840-tudl9k1g.txt
txt: txt/cord-260840-tudl9k1g.txt
title:
  Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model

summary:
  The prevalence of PRRSV RNA positive pigs and group mean genomic copy numbers/ml are summarized in Table 6 . Grey shaded areas indicate the presence of PCV2 seropositive pigs (S/P ratio > 0.2) within a treatment group.


id: cord-310844-7i92mk4x
author: Hryhorowicz, Magdalena
title: Application of Genetically Engineered Pigs in Biomedical Research
date: 2020-06-19
extension: .txt
mime: text/plain
words: 9041
sentence: 365
flesch: 32
cache: cache/cord-310844-7i92mk4x.txt
txt: txt/cord-310844-7i92mk4x.txt
summary:
  Moreover, other carbohydrate xenoantigens present on pig cells but absent in humans have been identified and include Neu5Gc antigen (N-glycolylneuraminic acid) catalyzed by cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMAH) and the SDa antigen produced by beta-1,4-N-acetyl-galactosaminyltransferase 2 (β4GALNT2). In addition, it was demonstrated that the introduction of the HLA-E gene into the porcine genome may also protect pig cells from macrophage-mediated cytotoxicity [85] .


id: cord-350626-ov9fy10b
author: Nazki, Salik
date: 2020-05-13
extension: .txt
mime: text/plain
words: 9925
sentence: 325
flesch: 41
cache: cache/cord-350626-ov9fy10b.txt
txt: txt/cord-350626-ov9fy10b.txt
title:
  Evaluation of local and systemic immune responses in pigs experimentally challenged with porcine reproductive and respiratory syndrome virus

summary:
  T cells, in turn, play a critical role in the development of anti-PRRSV immunity due to their cytotoxic effector functions in clearing infected cells from the body and developing and regulating antigen-specific immune responses [12] . Delayed induction of Th1, Th17 and CTL responses was observed in the PBMC of the infected pigs after 21 dpc, when most of the virus had been cleared from the blood, whereas in BLN, the virus persists for a longer period, which leads to early and sustained (> 35 dpc) induction of T cell responses.


id: cord-003640-psnec2qp
author: Mbareche, Hamza
title: Bioaerosols Play a Major Role in the Nasopharyngeal Microbiota Content in Agricultural Environment
date: 2019-04-16
extension: .txt
mime: text/plain
words: 10138
sentence: 429
flesch: 42
cache: cache/cord-003640-psnec2qp.txt
txt: txt/cord-003640-psnec2qp.txt
summary:
  Other important examples related to human health include, the greater differential abundance of Haemophilus influenzae in non-exposed controls (950 sequences in non-exposed control samples vs. 5 in samples from pig farmers), and the differential abundance of Klebsiella in samples from pig farmers (400 sequences in pig farmer samples vs. 3 in non-exposed controls). Other important examples related to human health include, the greater differential abundance of Haemophilus influenzae in non-exposed controls (950 sequences in non-exposed control samples vs. 5 in samples from pig farmers), and the differential abundance of Klebsiella in samples from pig farmers (400 sequences in pig farmer samples vs. 3 in non-exposed controls).


id: cord-283545-vu8lt3w6
author: Brabb, Thea
title: Infectious Diseases
date: 2011-12-16
extension: .txt
mime: text/plain
words: 28881
sentence: 1302
flesch: 42
cache: cache/cord-283545-vu8lt3w6.txt
txt: txt/cord-283545-vu8lt3w6.txt
summary:
  Otitis media, conjunctivitis, and an inflamed prostate gland are signs that have been associated with Pseudomonas in other reports of guinea pig infection (Fox, 2002) . key: cord-283545-vu8lt3w6 authors: Brabb, Thea; Newsome, Denise; Burich, Andrew; Hanes, Martha title: Infectious Diseases date: 2011-12-16 journal: The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents DOI: 10.1016/b978-0-12-380920-9.00023-7 sha: doc_id: 283545 cord_uid: vu8lt3w6 Although guinea pigs are sensitive and susceptible to the development of lesions from a wide range of viruses, bacteria, protozoa, and parasites, only a small number of organisms cause natural infection and only a portion of that group cause clinical disease.


id: cord-304720-0lgup7yj
author: Robbins, R.C.
title: Swine Diseases and Disorders
date: 2014-08-21
extension: .txt
mime: text/plain
words: 12875
sentence: 715
flesch: 41
cache: cache/cord-304720-0lgup7yj.txt
txt: txt/cord-304720-0lgup7yj.txt
summary:
  A postmortem examination, or necropsy, of affected pigs should occur last. Bacteriologic isolation of a β-hemolytic strain of E. coli from affected pigs with meningoencephalitis is not sufficient for a diagnosis.


# ent

id: cord-009820-fi54s0x7
sid: 17
eid: 5
type: PERSON
entity:
  regelmäßig von den tonsillen und dem respirationstrakt und gelegentlich vom gewebe des pons‐medulla‐bereiches sowie aus der magenwand reisoliert werden.


