id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-352465-n746e8qt	Wang, Fei	Targeting stress granules: A novel therapeutic strategy for human diseases	2020-08-16		.txt	text/plain	9163	409	35	TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis Stress granules and cell signaling: more than just a passing phase? Cap-dependent, scanning-free translation initiation mechanisms Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase Stress granules: the Tao of RNA triage Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response Stressful initiations Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation Hippuristanol-A potent steroid inhibitor of eukaryotic initiation factor 4A Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation Eukaryotic Initiation Factor 2α-independent Pathway of Stress Granule Induction by the Natural Product Pateamine A Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1 The RasGAPassociated endoribonuclease G3BP assembles stress granules Unravelling the ultrastructure of stress granules and associated P-bodies in human cells Principles and Properties of Stress Granules Liquid phase condensation in cell physiology and disease Distinct stages in stress granule assembly and disassembly P bodies promote stress granule assembly in Saccharomyces cerevisiae Possible Roles in the Control of Translation and mRNA Degradation Eukaryotic stress granules are cleared by granulophagy and Cdc48/VCP function A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism Stress granules: sites of mRNA triage that regulate mRNA stability and translatability Dynein and kinesin regulate stressgranule and P-body dynamics Translation inhibition and stress granules in the antiviral immune response Stress granules and neurodegeneration The involvement of stress granules in aging and aging-associated diseases Stress granule: A promising target for cancer treatment Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease Differences between acute and chronic stress granules, and how these differences may impact function in human disease Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules The chemotherapeutic agent bortezomib induces the formation of Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways RhoA/ROCK1 signaling regulates stress granule formation and apoptosis Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation Regulation of stress granules in virus systems Mammalian Orthoreovirus Particles Induce and Are Recruited into Stress Granules at Early Times Postinfection Influenza A virus inhibits cytoplasmic stress granule formation Respiratory Syncytial Virus Induces Host RNA Stress Granules To Facilitate Viral Replication Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies Picornavirus 2A protease regulates stress granule formation to facilitate viral translation Stress granules (SG) and processing bodies (PB) in viral infections SARS-CoV-2 Nucleocapsid Protein Impairs SG Assembly by Partitioning into G3BP Condensate Nucleocapsid protein of SARS-CoV-2 phase separates into RNArich polymerase-containing condensates A SARS-CoV-2 protein interaction map reveals targets for drug repurposing The Global Phosphorylation Landscape of SARS-CoV-2 Infection Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases Emerging small-molecule therapeutic approaches for amyotrophic lateral sclerosis and frontotemporal dementia Converging Mechanisms in ALS and FTD: Check your RNA granule aggregation A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins A new subtype of frontotemporal lobar degeneration with FUS pathology TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA Dissecting the molecular mechanisms that impair stress granule formation in aging cells Stress granules counteract senescence by sequestration of PAI-1 DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome Activation of the integrated stress response during T helper cell differentiation Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions Presence and function of stress granules in atrial fibrillation The Kinase Inhibitor Sorafenib Induces Cell Death through a Process Involving Induction of Endoplasmic Reticulum Stress Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells Clinical Pharmacology of 5-Fluorouracil 5-Fluorouracil affects assembly of stress granules based on RNA incorporation Proteasome inhibitors in cancer therapy Psammaplysin F increases the efficacy of bortezomib and sorafenib through regulation of stress granule formation Psammaplysin F, a New Bromotyrosine Derivative from a Sponge, Aplysinella sp Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response Protein synthesis in eukaryotes: the growing biological relevance of cap-independent translation initiation The Unfolded Protein Response Triggers Selective mRNA Release from the Endoplasmic Reticulum The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly Nitric oxide triggers the assembly of type II stress granules linked to decreased cell viability Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism Malonate induces the assembly of cytoplasmic stress granules Molecular Pathways: The eIF4F Translation Initiation Complex-New Opportunities for Cancer Treatment 15-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism Translational Dysregulation by Pateamine A A comparative study of small molecules targeting eIF4A Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography One-thousand-and-one substrates of protein kinase CK2?	cache/cord-352465-n746e8qt.txt	txt/cord-352465-n746e8qt.txt
