        item: #1 of 50
          id: cord-005842-mm3ab7cr
      author: Sado, Toshiyuki
       title: Inflammatory pattern recognition receptors and their ligands: factors contributing to the pathogenesis of preeclampsia
        date: 2011-03-06
       words: 6579
      flesch: 31
     summary: Hypertension Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice Tolllike receptor signaling and pre-eclampsia Endogenous damage-associated molecular pattern molecules at the crossroads of inflammation and cancer Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia Microarray analysis of differentially expressed fetal genes in placental tissue derived from early and late onset severe pre-eclampsia Effect of hypoxia and exogenous IL-10 on the pro-inflammatory cytokine TNF-alpha and the anti-angiogenic molecule soluble Flt-1 in placental villous explants Managing patients with metastatic colorectal cancer on bevacizumab Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women Decreased proportion of peripheral blood vascular endothelial growth factor-expressing T and natural killer cells in preeclampsia Dysregulation of anti-angiogenic agents (sFlt-1, PLGF, and sEndoglin) in preeclampsia-a step forward but not the definitive answer Regulation of soluble vascular endothelial growth factor receptor (sFlt-1/sVEGFR-1) expression and release in endothelial cells by human follicular fluid and granulosa cells The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD TGF beta signalling and its role in tumour pathogenesis Can the biology of VEGF and haem oxygenases help solve pre-eclampsia? Systemic and uteroplacental reninangiotensin system in normal and pre-eclamptic pregnancies Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling The functional role of the renin-angiotensin system in pregnancy and preeclampsia Clinical implications for vascular endothelial growth factor in the lung: friend or foe? Adhesion system VEGF is a potent angiogenic and pro-inflammatory cytokine that increases vascular permeability, angiogenesis, vasculogenesis, endothelial cell growth, migration, adhesion, and anti-apoptosis, partly via upregulation of endothelial cell and leukocyte adhesion molecule expression
    keywords: cells; endothelial; expression; factor; gene; growth; inflammation; ligands; oxidative; preeclampsia; protein; rage; receptor; stress; vascular; vegf
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        item: #2 of 50
          id: cord-009966-6kcgc5fx
      author: Warren, Kimberly R.
       title: Role of chronic stress and depression in periodontal diseases
        date: 2013-12-09
       words: 6823
      flesch: 21
     summary: Psychological stress refers to the emotional and physiological reactions experienced when a person confronts a life event, such as marital conflict, financial debt or death of a loved one, that exceeds his or her ability to cope effectively with the situation. The search terms psychiatry, psychological stress, depression, dental, periodontal disease, periodontitis, teeth, oral health, and immune function were used in the searches.
    keywords: chronic; depression; disease; immune; inflammation; levels; patients; periodontitis; psychological; risk; stress; studies; system
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        item: #3 of 50
          id: cord-011261-h1fzti0i
      author: Manning-Geist, Beryl
       title: Pre-clinical Stress Management Workshops Increase Medical Students’ Knowledge and Self-awareness of Coping with Stress
        date: 2019-12-09
       words: 3423
      flesch: 40
     summary: N Medical student stress and burnout Using a single item to measure burnout in primary care staff: a psychometric evaluation Burnout in medical students: a systematic review The learning environment and medical student burnout: a multicentre study A longitudinal study of students' depression at one medical school Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students Medical student depression, anxiety and distress outside North America: a systematic review Distress among matriculating medical students relative to the general population Burnout among U.S. medical students, residents, and early career physicians relative to the general U.S. population Prevalence of depression, depressive symptoms, and suicidal ideation among medical students: a systematic review and meta-analysis Medical student stress: an elective course as a possibility of help The effect of mind body medicine course on medical student empathy: a pilot study Effects of mindfulness-based stress reduction on medical and premedical students Cultivating personcentered medicine in future physicians Mindfulness-based stress reduction lowers psychological distress in medical students Effects of mindfulness-based stress reduction on the mental health of clinical clerkship students: a cluster-randomized controlled trial Abridged mindfulness intervention to support wellness in first-year medical students A randomised controlled trial of the effects of mindfulness practice on medical student stress levels Medical students' differential use of coping strategies as a function of stressor type, year of training, and gender Towards and understanding of resilience and its relevance to medical training Toward creating physician healers: fostering medical students self-awarenss, personal growth, and well being Use manual for the coping strategies inventory Maslach burnout inventory manual Validity of the Maslach burnout inventory for family practice physicians Burnout and empathy in primary care: three hypotheses Learning in a high-stress clinical environment: stressors associated with medical students' clerkship training on labor and delivery Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Dyrbye and colleagues revealed that the learning environment was significantly associated with medical student burnout; specifically, students rotating on hospital wards and those required to stay for overnight call were more likely to experience burnout
    keywords: burnout; knowledge; post; strategies; stress; students; workshop
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        item: #4 of 50
          id: cord-017817-ztp7w9yh
      author: Land, Walter Gottlieb
       title: Cell-Autonomous (Cell-Intrinsic) Stress Responses
        date: 2018-03-28
       words: 17769
      flesch: 34
     summary: A typical example is represented by oxidative stress and ER stress responses, which appear to act mutually in any form of cellular damage. ATF activating transcription factor, CHOP cytidine-cytidine-adenosine-adenosine thymidine-enhancer-binding homologous protein, eIF2α eukaryotic translational initiation factor 2α, ER endoplasmic reticulum, IRE1α inositol-requiring transmembrane kinase/endoribonuclease 1α, PERK protein kinase-like eukaryotic initiation factor 2α kinase, UPR unfolded protein response, XBP1 X-box binding protein 1. XBP1s, X-box binding protein 1 whereby the s stands for the spliced form of XBP1.
    keywords: autophagy; cell; complex; damage; damps; degradation; dna; example; heat; immune; innate; keap1; mechanisms; membrane; nrf2; oxidative; pathway; process; protein; regulation; response; role; ros; signalling; stress; stress response; transcription; upr
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        item: #5 of 50
          id: cord-022506-fkddo12n
      author: Griffin, Brenda
       title: Population Wellness: Keeping Cats Physically and Behaviorally Healthy
        date: 2011-12-05
       words: 23812
      flesch: 46
     summary: Indeed, veterinarians may be tasked with developing health care programs for cat populations in a wide spectrum of settings-from facilities housing laboratory animals, to animal shelters, home-based rescue and foster providers, care-for-life cat sanctuaries, breeding catteries, or large multicat households. In particular, upper respiratory disease is the most common endemic disease in cat populations and is impossible to completely prevent in an open population.
    keywords: addition; animal; areas; behavioral; care; cats; control; disease; environment; feline; figure; group; health; housing; individual; infection; kittens; physical; population; setting; shelter; stress; time; use; vaccination; wellness
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        item: #6 of 50
          id: cord-028176-wsveq2hk
      author: Alcibiade, Alessandro
       title: Reliability in Extreme Isolation: A Natural Language Processing Tool for Stress Self-assessment
        date: 2020-05-29
       words: 2804
      flesch: 38
     summary: From isolation of people in case of an epidemic (Ebola, Coronavirus, ..) to mineworkers or scientist in the Antarctic environment, it is currently well established that extreme isolation is a stressor element which negatively affects human creating stress and social conflict. From isolation of people in case of an epidemic (Ebola, Coronavirus, ..) to mineworkers or scientist in the Antarctic environment, it is currently well established that extreme isolation is a stressor element which negatively affects human creating stress and social conflict.
    keywords: analysis; human; isolation; language; nlp; space; stress
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        item: #7 of 50
          id: cord-030805-3imi63xz
      author: Lodha, Surabhi
       title: Book Review: Stress Less, Accomplish More: Meditation for Extraordinary Performance
        date: 2020-08-07
       words: 1205
      flesch: 47
     summary: They came across the videos of Emily Fletcher teaching Ziva meditation online. It is an amalgamation of ancient meditation practices, modern neuroscience, and pop psychology sans metaphysics or spirituality.
    keywords: meditation; practice; stress; technique
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        item: #8 of 50
          id: cord-256132-ufs9kw3o
      author: AlAteeq, Deemah A.
       title: Perceived stress among students in virtual classrooms during the COVID-19 outbreak in KSA
        date: 2020-08-01
       words: 3033
      flesch: 51
     summary: Females had a significantly higher mean score of perceived stress level compared to males (22.75 versus 20.27; p Q27 -value ¼ 0.003). Females and university students showed a significant association with stress level (p-value = 0.003 and 0.049, respectively).
    keywords: covid-19; ksa; level; outbreak; stress; students; university
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        item: #9 of 50
          id: cord-256504-odbaubqm
      author: Kuo, Fang‐Li
       title: Survey on perceived work stress and its influencing factors among hospital staff during the COVID‐19 pandemic in Taiwan
        date: 2020-08-19
       words: 3210
      flesch: 46
     summary: This could be attributed to physical discomfort caused by protective equipment, also, nurses often Previous studies have shown that work stress is related to one's demographic characteristics, 13, 17 and that child care at home is a common problem for hospital staff, 28, 29 which is an important factor leading to work-family conflicts. Among participants who experienced severe stress (n = 129), work stress was higher among those with rather than without minor children.
    keywords: hospital; nurses; pandemic; staff; stress; study; taiwan; work
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        item: #10 of 50
          id: cord-262551-hxhlhb5m
      author: van der Gronde, Toon
       title: Toward a New Model of Understanding, Preventing, and Treating Adolescent Depression Focusing on Exhaustion and Stress
        date: 2020-05-06
       words: 5761
      flesch: 34
     summary: Psychedelic drugs in the treatment of anxiety, depression and addiction Serotonergic hallucinogens in the treatment of anxiety and depression in patients suffering from a life-threatening disease: A systematic review Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Psilocybin for treatment-resistant depression: fMRImeasured brain mechanisms Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depression Antidepressant actions of ketamine: from molecular mechanisms to clinical practice Ketamine and nitrous oxide: The evolution of NMDA receptor antagonists as antidepressant agents Esketamine for treatment resistant depression: a trick of smoke and mirrors? Understanding, Preventing, and Treating Adolescent Depression Frontiers in Psychiatry | www Therapeutic effect of increased openness: Investigating mechanism of action in MDMA-assisted psychotherapy IL-6 and depression: A systematic review and meta-analysis of longitudinal studies Inflammatory biomarkers and depression Toward a revised evolutionary adaptationist analysis of depression: the social navigation hypothesis Cognitive bias modification for anxiety: current evidence and future directions From Hans Selye's discovery of biological stress to the identification of corticotropin-releasing factor signaling pathways: implication in stress-related functional bowel diseases What does the legacy of Hans Selye and Franz Alexander mean today? In later years, reduced adult neurogenesis and changes in structural and functional neuronal plasticity have been linked to the onset and treatment opportunities of major depression (10, 11) .
    keywords: adolescents; behavior; coping; depression; disorder; exhaustion; mood; patients; review; stress; symptoms; treatment
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        item: #11 of 50
          id: cord-263518-6puccigu
      author: Maarefvand, Masoomeh
       title: Coronavirus Outbreak and Stress in Iranians
        date: 2020-06-20
       words: 4927
      flesch: 44
     summary: Second, this study measured the prevalence of variables rather than incident cases, and we were unable to assess the levels of variables before COVID-19 outbreak in Iran as a control. Coronavirus Map: Tracking the Global Outbreak Estimation of coronavirus disease 2019 (COVID-19) Burden and potential for international dissemination of infection from Iran Public education and electronic awareness of the new Coronavirus (COVID-19): Experiences from Iran Update: Public Health Response to the Coronavirus Disease 2019 outbreak-United States Clinical features of patients infected with 2019 novel coronavirus in Wuhan Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: A model of West China Hospital.
    keywords: covid-19; groups; health; information; outbreak; people; risk; social; stress; study
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        item: #12 of 50
          id: cord-267907-zbsbqj9o
      author: Brown, Samantha M.
       title: Stress and Parenting during the Global COVID-19 Pandemic
        date: 2020-08-20
       words: 7982
      flesch: 38
     summary: Manual The effects of economic hardship on family relationships among African American, Latino, and Euro-American families Ethnic differences in family stress processes among African-Americans and Black Carribeans The dark side of inclusion: Undesired acceptance increases aggression Stress exposure and depression in disadvantaged women: The protective effects of optimism and perceived control ADHD and parental psychological distress: Role of demographics, child behavioral characteristics, and parental cognitions Loneliness matters: A theoretical and empirical review of consequences and mechanisms head: STRESS, PARENTING, AND COVID-19 Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Relations between parenting stress, parenting style, and child executive functioning for children with ADHD or autism Racial and ethnic residential segregation and household structure: A research note Examining dynamic links between perceived control and health: Longitudinal evidence for differential effects in midlife and old age The SARS (Severe Acute Respiratory Syndrome) pandemic in Hong Kong: Effects on the subjective wellbeing of elderly and younger people Cognitive and coping processes in emotion A cumulative risk model of child physical maltreatment head: STRESS, PARENTING, AND COVID-19 33 potential: Findings from a community-based study The association between perceived provider discrimination, health care utilization, and health status in racial and ethnic minorities Protective factors among families with children at risk of maltreatment: Follow up to early school years A test of missing completely at random for multivariate data with missing values Familial financial stress and child internalizing behaviors: The roles of caregivers' maltreating behaviors and social services Socioeconomic inequalities in depression: A meta-analysis The psychological impact of COVID-19 pandemic in Italy: A lesson for mental health prevention in the first severely hit European city Maternal variations in stress reactivity: Implications for harsh parenting practices with very young children Predictors of parenting stress for abusive and nonabusive mothers The Child Abuse Potential Inventory: Manual Prediction and explanation of child abuse The correlation between stress and economic crisis: A systematic review The brief Child Abuse Potential Inventory: Development and validation Qualitative methods in social work research Perceived control and mindfulness: Implications for clinical practice Child maltreatment as a function of cumulative family risk: Findings from the intensive family preservation program Barriers to care among racial/ethnic groups under managed care Mental health before and during the COVID-19 pandemic: A longitudinal probability sample survey of the UK population The Lancet Psychiatry. Because emerging research has shown that families of diverse racial and ethnic identities may be disproportionately impacted by the COVID-19 pandemic, chi-square and one-way ANOVA analyses were conducted to examine whether there were racial and ethnic differences in COVID-19 risk factors, mental health risk factors, and protective factors.
    keywords: abuse; child; covid-19; factors; families; health; parenting; potential; risk; stress
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        item: #13 of 50
          id: cord-270469-lle32mha
      author: Martinon, Fabio
       title: The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses
        date: 2012-07-15
       words: 5867
      flesch: 35
     summary: Similarly injection into mice of media supernatant harvested from ERstressed cells elicit the upregulation of genes typically associated with ER stress responses in the liver Conditions of ER stress occur when the amount of proteins entering the ER exceeds its folding capacity.
    keywords: activation; cells; factor; ire1; pathways; protein; response; reticulum; signaling; stress; xbp1
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        item: #14 of 50
          id: cord-272268-8vrcwwll
      author: Kedersha, Nancy
       title: Chapter 4 Regulation of Translation by Stress Granules and Processing Bodies
        date: 2009-10-27
       words: 8608
      flesch: 34
     summary: The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response Disruption of microtubules inhibits cytoplasmic ribonucleoprotein stress granule formation Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules hnRNP A1 relocalization to the stress granules reflects a role in the stress response Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response Microtubuledependent association of AKAP350A and CCAR1 with RNA stress granules Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP TDRD3, a novel tudor domain-containing protein, localizes to cytoplasmic stress granules Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit Recycling of eukaryotic posttermination ribosomal complexes Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase How viruses avoid stress Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation Reovirus induces and benefits from an integrated cellular stress response Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies Interactions between brome mosaic virus RNAs and cytoplasmic processing bodies Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules A micrococcal nuclease homologue in RNAi effector complexes Inosine-containing dsRNA binds a stress-granule-like complex and downregulates gene expression in trans LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNAi RISC Retrotransposons revisited: the restraint and rehabilitation of parasites Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly Activation of the integrated stress response during T helper cell differentiation A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay Prolonged translation arrest in reperfused hippocampal cornu Ammonis 1 is mediated by stress granules Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules Post-translational arginylation of calreticulin: a new isospecies of calreticulin component of stress granules Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs Identification of FUSE-binding proteins as interacting partners of TIA proteins The cold-inducible RNAbinding protein migrates from the nucleus to cytoplasmic stress granules by a methylationdependent mechanism and acts as a translational repressor The eIF4G-homolog p97 can activate translation independent of caspase cleavage MBNL1 associates with YB-1 in cytoplasmic stress granules The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3 The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay Regulation of stress granule dynamics by Grb7 and FAK signalling pathway Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response Functional dissection of the human TNRC6 (GW182-related) family of proteins Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments Stress granule assembly is mediated by prion-like aggregation of TIA-1 HuR binding to cytoplasmic mRNA is perturbed by heat shock Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs Intracellular localization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci Identification of novel argonaute-associated proteins Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP Inhibition of G(1) to S phase progression by a novel zinc finger protein P58(TFL) at P-bodies Identification of PatL1, a human homolog to yeast P body component Pat1 Selective localization of PCBP2 to cytoplasmic processing bodies Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1 Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules Rpp 20 interacts with SMN and is re-distributed into SMN granules in response to stress The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs Sam68 functions in nuclear export and translation of HIV-1 RNA SGNP: an essential Stress Granule/Nucleolar Protein potentially involved in 5.8s rRNA processing/transport Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes Mammalian Staufen 1 is recruited to stress granules and impairs their assembly Survival motor neuron protein facilitates assembly of stress granules Probing the mRNA processing body using protein macroarrays and autoantigenomics ZBP1 regulates mRNA stability during cellular stress A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2a to the assembly of mammalian stress granules Cytoplasmic heat shock granules are formed from precursor particles and are associated with a specific set of mRNAs Plant stress granules and mRNA processing bodies are distinct from heat stress granules Mammalian stress granules: highly dynamic sites of mRNA triage during stress induced translational arrest TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation Stressful initiations Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes The RasGAPassociated endoribonuclease G3BP assembles stress granules Rasputin, more promiscuous than ever: a review of G3BP MK2-induced tristetraprolin: 14-3-3 complexes prevent stress granule association and ARE-mRNA decay Inhibition of eukaryotic translation initiation by the marine natural product pateamine A RNAmediated sequestration of the RNA helicase eIF4A by pateamine A inhibits translation initiation Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation An antiviral response directed by PKR phosphorylation of the RNA helicase A Decapping and decay of messenger RNA occur in cytoplasmic processing bodies Cytoplasmic foci are sites of mRNA decay in human cells P bodies: at the crossroads of post-transcriptional pathways P bodies and the control of mRNA translation and degradation The highways and byways of mRNA decay The control of mRNA decapping and P-body formation Perk is essential for translational regulation and cell survival during the unfolded protein response Signal integration via PKR The exonjunction-complex-component metastatic lymph node 51 functions in stress-granule assembly Distinctive properties of the 5'-untranslated region of human hsp70 mRNA Mammalian stress granules and processing bodies Translational control is required for the unfolded protein response and in vivo glucose homeostasis Metazoan stress granule assembly is mediated by P-eIF2 {alpha}-dependent and -independent mechanisms Heme-regulated inhibitor (HRI) kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF2) inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae P bodies promote stress granule assembly in Saccharomyces cerevisiae Robust heat shock induces eIF2{alpha}-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae Stress granules and processing bodies are dynamically linked sites of mRNP remodeling Subnuclear organelles: new insights into form and function The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly Dynein motor contributes to stress granule dynamics in primary neurons
    keywords: assembly; binding; bodies; cells; eif2a; formation; granules; initiation; mrna; pbs; proteins; response; sgs; stress; tia-1; translation; virus
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        item: #15 of 50
          id: cord-272406-h22atwd4
      author: Diotaiuti, Pierluigi
       title: The Principal at Risk: Stress and Organizing Mindfulness in the School Context
        date: 2020-08-31
       words: 6297
      flesch: 38
     summary: (1) Monitor the stress levels of a large sample of principals belonging to different levels of Italian schools; (2) verify the incidence of specific pathologies associated with high levels of school stress; (3) evaluate the relationships between the perceived stress, work discomfort and dimensions of organizational mindfulness; (4) test the fit of a general path model illustrating the influence of the predictors on principals' work discomfort; and (5) identify the role of organizing mindfulness on principal's perceived work discomfort. Principal stress has even been associated with severe problems such as ischemia and heart problems [48] .
    keywords: anxiety; awareness; discomfort; mindfulness; principals; problems; scale; school; stress; study; value; work; work discomfort
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        item: #16 of 50
          id: cord-279214-7vna4uyo
      author: Goldfarb, Elizabeth V.
       title: Participant stress in the COVID-19 era and beyond
        date: 2020-09-25
       words: 1578
      flesch: 41
     summary: There are various techniques for inducing stress responses in the labora tory, including physical, psychological and cogni tive chal lenges 5 . When designing studies to examine stress effects, a 'control group' is typically included to match a 'stress group' in as many ways as possible, short of the stress exposure.
    keywords: human; pandemic; participants; responses; stress
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        item: #17 of 50
          id: cord-280605-2i4gk7et
      author: Bachmann, María Consuelo
       title: The Challenge by Multiple Environmental and Biological Factors Induce Inflammation in Aging: Their Role in the Promotion of Chronic Disease
        date: 2020-10-14
       words: 11154
      flesch: 18
     summary: The impact on Tregulatory cell related immune responses in rural women exposed to polycyclic aromatic hydrocarbons (PAHs) in household air pollution in Gansu, China: A pilot investigation PM 2.5 induced pulmonary fibrosis in vivo and in vitro Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF-b1-Dependent and -Independent Mechanisms Effects of sub-chronic exposure to atmospheric PM2.5 on fibrosis, inflammation, endoplasmic reticulum stress and apoptosis in the livers of rats Genetic and epigenetic alterations in normal and sensitive COPD-diseased human bronchial epithelial cells repeatedly exposed to air pollution-derived Effects of airborne pollutants on mitochondrial DNA Methylation Prenatal particulate air pollution and DNA methylation in newborns: An epigenomewide meta-analysis Dose-and time-effect responses of DNA methylation and histone H3K9 acetylation changes induced by traffic-related air pollution Air pollution and DNA methylation: Effects of exposure in humans Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review Air pollution, particulate matter composition and methylation-based biologic age Air Pollution Stress and the Aging Phenotype: The Telomere Connection The effect of exposure time and concentration of airborne PM2.5 on lung injury in mice: A transcriptome analysis Facing up to the global challenges of ageing Coming of age: molecular drivers of aging and therapeutic opportunities Find the latest version: Review series introduction Coming of age: molecular drivers of aging and therapeutic opportunities Disability incidence and functional decline among older adults with major chronic diseases Quality of life assessment instruments for adults: a systematic review of population-based studies Comparative financing analysis and political economy of noncommunicable diseases The integration of inflammaging in age-related diseases Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimer's disease pathophysiology Source of Chronic Inflammation in Aging Microglial cell dysregulation in brain aging and neurodegeneration Aging and the immune system: An overview Cellular senescence and Alzheimer disease: the egg and the chicken scenario The epigenetics of inflammaging: The contribution of age-related heterochromatin loss and locus-specific remodelling and the modulation by environmental stimuli These sex-related differences can determine the ability of immune cells to generate an effective inflammatory response, which translates into epidemiological differences on the prevalence of various pathologies, including allergies (22), asthma (23, 24), autoimmune diseases (25), anaphylaxis (26), neonatal sepsis (27), and cancer (28), among several pathologies.
    keywords: activation; age; aging; cells; changes; cytokines; damage; diet; diseases; effects; exercise; exposure; expression; factors; immune; inflammation; levels; mechanisms; methylation; oxidative; production; response; sex; stress; system
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        item: #18 of 50
          id: cord-286416-8eu6wp9b
      author: Valiente-Echeverría, Fernando
       title: Viral modulation of stress granules
        date: 2012-06-14
       words: 5583
      flesch: 34
     summary: While the details on the mechanisms by which viruses elicit favorable environments in which to replicate will require further work, the sequestration of critical factors for the induction of SGs by viral proteins appears to be an increasingly studied area of research and should yield important new information on how viruses gain control over host cell biology. This observation likely indicates that viral proteins or viral RNA could locally disassemble SG to favor viral translation and this was shown to correlate with increased vRNA levels (McInerney et al., 2005) .
    keywords: assembly; cells; eif2; et al; granules; infection; protein; rna; sgs; stress; virus
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        item: #19 of 50
          id: cord-288101-pij16jaa
      author: Li, Jun-Yu
       title: Proteomic analysis of the response of porcine adrenal gland to heat stress
        date: 2019-02-28
       words: 5160
      flesch: 36
     summary: This conclusion follows directly from data suggesting that heat stress reduces the expression of heat shock proteins, handicapping their ability to induce a protective immune response when immunocytes are confronted with foreign entities. Among these 226 DEPs, tubulin and heat shock protein (HSP) such as HSP70, HSP60, HSP27, and Histone H2A might be involved in the regulation of heat stress.
    keywords: adrenal; analysis; cell; deps; fig; function; gland; heat; heat stress; pigs; proteins; response; stress
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        item: #20 of 50
          id: cord-292853-xihpfidg
      author: Ford, Julian D.
       title: Social, cultural, and other diversity issues in the traumatic stress field
        date: 2015-08-07
       words: 18827
      flesch: 28
     summary: Such an approach is consistent with new theoretical views of refugee traumatic stress, which include the concepts of cultural bereavement, cultural trauma, family consequences of refugee trauma, community trauma, and social suffering (Weine, 2008) . Because not all psychologists have expertise in assessing traumatic stress risk and/or social psychological (Continued ) factors, the assessment should be conducted by psychologists who have this specific expertise.
    keywords: abuse; american; children; community; cross; disaster; disorder; exposure; family; girls; groups; health; people; persons; psychological; psychologists; ptsd; refugees; risk; services; stress; stressors; study; symptoms; torture; trauma; treatment; united; violence; women
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        item: #21 of 50
          id: cord-294422-hsqphc3t
      author: Sandesh, Ram
       title: Impact of COVID-19 on the Mental Health of Healthcare Professionals in Pakistan
        date: 2020-07-02
       words: 1854
      flesch: 50
     summary: Novel coronavirus (2019-nCoV) situation reports Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations Mental health survey of 230 medical staff in a tertiary infectious disease hospital for COVID-19 The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients Vicarious traumatisation in the general public, members, and non-members of medical teams aiding in COVID-19 control Pandemic fear and COVID-19: mental health burden and strategies Safarizadeh MM: Stress, anxiety and depression among medical university students and its relationship with their level of happiness The psychological impact of severe acute respiratory syndrome outbreak on healthcare workers in emergency departments and how they cope Severe acute respiratory syndrome (SARS) and healthcare workers Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 The general public undertakes such safety measures, but health care professionals (HCPs) are unfortunately left exposed to deal with the many issues that arise due to this situation.
    keywords: anxiety; depression; health; stress
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        item: #22 of 50
          id: cord-294945-hcf7gsv8
      author: Lin, K.H.
       title: Comparative proteomic analysis of cauliflower under high temperature and flooding stresses
        date: 2015-02-12
       words: 8231
      flesch: 40
     summary: upon heat stress Drought-inhibition of photosynthesis in C3 plants: stomatal and non-stomatal limitations revisited Proteome analysis of wheat leaf under salt stress by two-dimensional difference gel electrophoresis (2D-DIGE) Comparative proteomic analysis of grain development in two spring wheat varieties under drought stress Physiology and proteome responses of two contrasting rice mutants and their wild type parent under salt stress conditions at the vegetative stage Comparative proteomic analysis of salt response proteins in seedling roots of two wheat varieties Proteome analysis of sugar beet leaves under drought stress Research on plant abiotic stress responses in the post-genome era: past, present and future Responses of antioxidative system to chilling stress in two rice cultivars differing in sensitivity Structural-functional state of thylakoid membranes of wheat genotypes under water stress Proteomic analysis of wheat embryos with 2-DE and liquid-phase chromatography (ProteomeLab PF-2D) -a For instance, proteomics approaches for the comparative analysis of protein abundance between untreated and stress-treated or tolerant and intolerant rice plants have greatly facilitated the study of plant cellular stress responses (Komatsu et al., 2003) .
    keywords: analysis; cauliflower; et al; flooding; h41; h69; h71; heat; peaks; plants; proteins; response; stress; stresses; table; temperature; treatments; water
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        item: #23 of 50
          id: cord-295767-92oxdmxq
      author: Aga, Syed Sameer
       title: Évaluation de la santé mentale et des diverses stratégies d'adaptation dans la population générale vivant sous l'emprise de la COVID à travers le monde : Une étude transversal
        date: 2020-07-28
       words: 3804
      flesch: 46
     summary: Our study aimed to investigate the immediate impact of the COVID-19 pandemic enforced lockdown on mental health and quality of life among general population aged 18 years and to identify various coping strategies used under lockdown. o To identify various coping strategies used under lockdown.
    keywords: anxiety; covid-19; depression; les; lockdown; participants; stress
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        item: #24 of 50
          id: cord-297673-rh8o4eu9
      author: Vahedian-Azimi, Amir
       title: Comparison of the severity of psychological distress among four groups of an Iranian population regarding COVID-19 pandemic
        date: 2020-08-08
       words: 4144
      flesch: 43
     summary: We hope our study findings will provide data support for the target intervention on psychological health in Iran and different parts of the world during the pandemic. Mental health and psychosocial considerations during the COVID-19 outbreak Factors associated with the psychological impact of severe acute respiratory syndrome on nurses and other hospital workers in Toronto Impact on health care workers employed in high-risk areas during the Toronto SARS outbreak Survey of stress reactions among health care workers involved with the SARS outbreak Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers The psychological impact of severe acute respiratory syndrome outbreak on healthcare workers in emergency departments and how they cope Concerns and preparedness for an avian influenza pandemic: a comparison between community hospital and tertiary hospital healthcare workers Oneyear outcomes and health care utilization in survivors of severe acute respiratory syndrome Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a casecontrolled study Stress and psychological distress among SARS survivors 1 year after the outbreak Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance Long-term stability of depression, anxiety, and stress syndromes Depression anxiety and stress scales (DASS-21): psychometric analysis across four racial groups The depression, anxiety and stress scale (DASS-21) as a screener for depression in substance use disorder inpatients: a pilot study Validation of the depression anxiety stress scales (DASS) 21 as a screening instrument for depression and anxiety in a rural community-based cohort of northern Vietnamese women Validation of depression anxiety and stress scale (DASS-21) for an Iranian population Effect of music on anxiety, stress, and depression levels in patients undergoing coronary angiography Immediate and sustained psychological impact of an emerging infectious disease outbreak on health care workers The forgotten plague: psychiatric manifestations of Ebola, Zika, and emerging infectious diseases Psychobehavioural responses to the 2014 Middle East respiratory syndrome-novel corona virus (MERS CoV) among adults in two shopping malls in Jeddah, western Saudi Arabia Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients Management of corona virus disease-19 (COVID-19): the Zhejiang experience.
    keywords: anxiety; covid-19; depression; health; medical; patients; population; stress; study
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        item: #25 of 50
          id: cord-302185-pnw3xiun
      author: Bodecka, Marta
       title: Gender as a moderator between Present-Hedonistic time perspective and depressive symptoms or stress during COVID-19 lock-down
        date: 2021-01-01
       words: 4544
      flesch: 44
     summary: However, compared to other time perspectives, PH time perspective was the most robust predictor of current emotional states (Stolarski, Matthews, Postek, Zimbardo, & Bitner, 2014) . The results of moderation analysis allowed for full acceptance of the hypothesis for depression as a factor, but for stress the hypothesis was only partially confirmed, since the relationship between PH time perspective and stress was not significant for men (although it was positive, as expected).
    keywords: depression; gender; lock; men; perspective; stress; symptoms; time; women
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        item: #26 of 50
          id: cord-302254-egt9qdib
      author: Amaral-Prado, Heloísa Monteiro
       title: The impact of confinement in the psychosocial behaviour due COVID-19 among members of a Brazilian university
        date: 2020-11-08
       words: 3753
      flesch: 41
     summary: For both periods analyzed, lower resilience scores lead to higher perceived stress and more accentuated depressive signs, as well as the greater resilience leads to an attenuation of the depressive signs, regardless of sex, university situation and period analyzed (Table 3) . High perceived stress can be associated with physical and psychological health problems, as well as with emotional intelligence and coping strategies employed (Enns et al., 2018) .
    keywords: covid-19; resilience; scores; signs; stress; university
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        item: #27 of 50
          id: cord-302616-1uwrcvjx
      author: Steenblock, Charlotte
       title: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis
        date: 2020-05-07
       words: 3877
      flesch: 33
     summary: On the use of corticosteroids for 2019-nCoV pneumonia Renin-angiotensin-aldosterone system inhibitors in patients with Covid-19 Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation The adrenal gland in stress -adaptation on a cellular level Hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes: sex differences in regulation of stress responsivity Sex differences and stress across the lifespan SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Origin and evolution of the 2019 novel coronavirus The renin-angiotensin-aldosterone system and its suppression Novel therapeutic approaches targeting the Renin-Angiotensin System and associated peptides in hypertension and heart failure The vasoprotective axes of the reninangiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases The ACE2/Angiotensin-(1-7)/MAS axis of the Renin-Angiotensin System: focus on angiotensin Classical Renin-Angiotensin system in kidney physiology Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig Increasing brain angiotensin converting enzyme 2 activity Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis decreases anxiety-like behavior in male mice by activating central Mas receptors Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Effects of Taurine on ACE, ACE2 and HSP70 expression of hypothalamicpituitary-adrenal axis in stress-induced hypertensive rats Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -an update on the status Multiple organ infection and the pathogenesis of SARS The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients COVID-19: the gendered impacts of the outbreak COVID-19 and Italy: what next? An appropriate response during acute stress is imperative for survival, but frequent or prolonged activation can change the functional tone of stress systems with ensuing deleterious effects.
    keywords: ace2; angiotensin; axis; cells; coronavirus; infection; patients; sars; stress; system
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        item: #28 of 50
          id: cord-304208-jwlc8fxj
      author: Vagni, Monia
       title: Coping With COVID-19: Emergency Stress, Secondary Trauma and Self-Efficacy in Healthcare and Emergency Workers in Italy
        date: 2020-09-03
       words: 8636
      flesch: 39
     summary: We study differences between healthcare (n = 121) and emergency workers (n = 89) in terms of their coping strategies, emergency stress, and secondary trauma, as well as the relationships of these differences to demographic variables and other stress factors (Instructions and Equipment). The analyses reveal that compared with the emergency worker group, the health worker group has greater levels of emergency stress and arousal and is more willing to use problem-focused coping.
    keywords: coping; covid-19; emergency; emergency workers; et al; factors; group; healthcare; levels; strategies; stress; study; trauma; workers
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        item: #29 of 50
          id: cord-309161-ceahghs1
      author: Epel, Elissa S.
       title: The geroscience agenda: What does stress have to do with it?
        date: 2020-09-28
       words: 7756
      flesch: 30
     summary: It is not just stress responses to major events that matter. Cannon's stress studies led to the popular concept of homeostasis (Cannon, 1932) but a simple linear model of homeostasis does not explain the range of human stress responses, and there have been many elaborations of this concept.
    keywords: acute; aging; capacity; et al; geroscience; health; hormesis; interventions; life; recovery; resilience; response; stress; stressors
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        item: #30 of 50
          id: cord-309273-gtvi37gh
      author: Flesia, Luca
       title: Predicting Perceived Stress Related to the Covid-19 Outbreak through Stable Psychological Traits and Machine Learning Models
        date: 2020-10-19
       words: 7913
      flesch: 40
     summary: A more complete descriptive analysis of each variable, including the composition of high perceived stress versus low perceived stress samples, is reported in the Supplementary Materials. The effects of psychological stress on depression Chronic stress, hair cortisol and depression: A prospective and longitudinal study of medical internship Heightened biological stress response during exposure to a trauma film predicts an increase in intrusive memories A direct test of the diathesis-stress model for depression Psychological stress and coping in adaptation and illness Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: A model of West China Hospital.
    keywords: control; covid-19; data; health; levels; model; participants; people; score; self; stress; study; traits
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        item: #31 of 50
          id: cord-309892-z7rb7adi
      author: TRAYLOR, Claire S.
       title: Effects of psychological stress on adverse pregnancy outcomes and non-pharmacologic approaches for reduction: an expert review
        date: 2020-09-24
       words: 5804
      flesch: 34
     summary: key: cord-309892-z7rb7adi authors: TRAYLOR, Claire S.; JOHNSON, Jasmine; Kimmel, Mary C.; MANUCK, Tracy A. title: Effects of psychological stress on adverse pregnancy outcomes and non-pharmacologic approaches for reduction: an expert review date: 2020-09-24 journal: Am J Obstet Gynecol MFM DOI: 10.1016/j.ajogmf.2020.100229 sha: doc_id: 309892 cord_uid: z7rb7adi Both acute and chronic stress can cause allostatic overload, or long-term imbalance in mediators of homeostasis, that results in disruptions in the maternal-placental-fetal endocrine and immune system responses. 13 81 Chronic stress may be associated with adverse pregnancy outcomes via a positive feedback 83 loop.
    keywords: anxiety; chronic; depression; exercise; health; outcomes; pharmacologic; pregnancy; stress; women; yoga
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        item: #32 of 50
          id: cord-312362-i18rlo2r
      author: Yan, Linlin
       title: The relationship between perceived stress and emotional distress during the COVID-19 outbreak: Effects of boredom proneness and coping style
        date: 2020-10-29
       words: 3821
      flesch: 34
     summary: The results showed that higher perceived stress was associated with more emotional distress including depression, fear, compulsion-anxiety, neurasthenia, and hypochondria. key: cord-312362-i18rlo2r authors: Yan, Linlin; Gan, Yiqun; Ding, Xu; Wu, Jianhui; Duan, Hongxia title: The relationship between perceived stress and emotional distress during the COVID-19 outbreak: Effects of boredom proneness and coping style date: 2020-10-29 journal: J Anxiety Disord DOI: 10.1016/j.janxdis.2020.102328 sha: doc_id: 312362 cord_uid: i18rlo2r
    keywords: anxiety; boredom; coping; covid-19; depression; distress; pandemic; proneness; stress
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        item: #33 of 50
          id: cord-314014-d9jwy5b6
      author: Duan, Hongxia
       title: Impact of the COVID-19 pandemic on mental health in the general Chinese population: Changes, predictors and psychosocial correlates
        date: 2020-08-18
       words: 4181
      flesch: 38
     summary: A systematic review, meta-analysis, and methodologic considerations for advancing the field The behavioral immune system: Implications for social cognition, social interaction, and social influence Age differences in brain activity during emotion processing: Reflections of age-related decline or increased emotion regulation Infectious disease prevalence, not race exposure, predicts both implicit and explicit racial prejudice across the United States Perceived discrimination and health: a meta-analytic review Social support and coping strategies as mediators of adult adjustment following childhood maltreatment Stress and the social brain: behavioural effects and neurobiological mechanisms The association between social relationships and depression: a systematic review Child abuse and neglect, social support, and psychopathology in adulthood: A prospective investigation Moderators and mediators of the stress-aggression relationship: Executive function and state anger Aggression, social stress, and the immune system in humans and animal models Psychological symptoms of ordinary Chinese citizens based on SCL-90 during the level I emergency response to COVID-19 Coping strategies and social support as mediators of consequences in child sexual abuse victims Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China A longitudinal study on the mental health of general population during the COVID-19 epidemic in China The second aim was to examine whether perceived stress level to the COVID-19 pandemic would predict an increase in hostility and whether coping strategies would play a potential intermediating role in the relationship between stress and hostility.
    keywords: coping; hostility; level; pandemic; stress; support
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        item: #34 of 50
          id: cord-316222-cm4k04wv
      author: Cozzolino, Mauro
       title: The Evaluation of a Mind-Body Intervention (MBT-T) for Stress Reduction in Academic Settings: A Pilot Study
        date: 2020-07-30
       words: 5609
      flesch: 50
     summary: The results of the paired-samples t-test conducted in undergraduate students showed that the level of post-treatment stress was statistically significantly different and lower than the level of pre-treatment stress (t (53) = 4.56, p < 0.001), as displayed in Figure 1 . Furthermore, the results of the paired-samples t-test conducted in graduate students showed that the level of post-treatment stress was statistically significantly different and lower than the level of pre-treatment stress (t (88) = 5.39, p < 0.001), as is also displayed in Figure 1 .
    keywords: graduate; hand; level; mbt; mind; post; stress; students; study; therapist
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        item: #35 of 50
          id: cord-316944-xt09q1z5
      author: Preis, Heidi
       title: Vulnerability and Resilience to Pandemic-Related Stress Among U.S. Women Pregnant at the Start of the COVID-19 Pandemic
        date: 2020-09-06
       words: 2071
      flesch: 27
     summary: Binary logistic regression was used to calculate odds ratios for high stress. Neither gestational age, fertility treatment (endorsed by 10.6% of the sample), psychiatric medication use (endorsed by 12.1% of the sample), nor diagnosis of COVID-19 during pregnancy were significant predictors of high stress in the unadjusted or adjusted models, indicating that high stress was equally common for women irrespective of these characteristics.
    keywords: pandemic; pregnancy; stress; women
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        item: #36 of 50
          id: cord-318363-1mv5j4w2
      author: Zvolensky, Michael J.
       title: Psychological, addictive, and health behavior implications of the COVID-19 pandemic
        date: 2020-08-27
       words: 15844
      flesch: 26
     summary: Although many of these relations would be expected, theoretically, to be negative, select subgroups will certainly adaptively respond to COVID-19 related stress (e.g., improve their physical fitness, improve self-care routines, quit/reduce maladaptive behaviors that place them at risk). Although this illustrative example represents only one of many possible transdiagnostic amplifying factors, it draws attention to the fact that individual differences in psychological processes are apt to play a central role in the relation between COVID-19 related stress and mental health, addictive behavior, health behavior, and chronic illness.
    keywords: alcohol; anxiety; behavior; cannabis; children; chronic; covid-19; covid-19 pandemic; disease; et al; factors; health; health behavior; hiv; illness; individuals; j o; pandemic; psychological; r n; risk; sleep; smoking; stress; symptoms; treatment; u r; use
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        item: #37 of 50
          id: cord-320208-uih4jf8w
      author: Li, Diya
       title: Modeling Spatiotemporal Pattern of Depressive Symptoms Caused by COVID-19 Using Social Media Data Mining
        date: 2020-07-10
       words: 8953
      flesch: 53
     summary: We assessed the level of stress expressed in COVID-19 related tweets by integrating a lexicon-based method derived from established clinical assessment questionnaire PHQ-9 Even though our datasets were preprocessed and selected with entities on COVID-19 related topic, some of the tweets might be outside of the topic or are influenced by other objective factors.
    keywords: accuracy; algorithm; analysis; assessment; covid-19; data; number; phq; results; stress; symptoms; topic; tweets; twitter; words
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        item: #38 of 50
          id: cord-324788-echu0zmf
      author: Aich, Palok
       title: Modern approaches to understanding stress and disease susceptibility: A review with special emphasis on respiratory disease
        date: 2009-07-30
       words: 7673
      flesch: 30
     summary: The current review focuses on (a) the effects of psychological stressors in humans and animals, (b) various methodologies employed to understand stress responses and their outcomes, and (c) the current status of the attempts to correlate stress and disease with respiratory disease as model system. Stress responses usually include physical perturbations that can encompass either the entire body or specifi c cellular compartments.
    keywords: ammatory; analysis; approaches; bovine; calves; disease; effects; expression; infection; infl; response; stress; stressors; studies; susceptibility; system; viral
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        item: #39 of 50
          id: cord-326788-qzm3b3xy
      author: Liew, Jean W.
       title: Patient‐reported Disease Activity in an Axial Spondyloarthritis Cohort during the COVID‐19 Pandemic
        date: 2020-09-06
       words: 3854
      flesch: 46
     summary: In this study, higher levels of perceived stress and anxiety, but not depression, were significantly associated with higher disease activity levels among individuals with axSpA. The impact of such stressors on disease activity in individuals with axial spondyloarthritis (axSpA) is unclear.
    keywords: activity; anxiety; basdai; disease; levels; patients; stress; study
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        item: #40 of 50
          id: cord-329206-xsxkn5my
      author: Vojtkovská, Veronika
       title: Methods of Assessment of the Welfare of Shelter Cats: A Review
        date: 2020-08-28
       words: 18228
      flesch: 43
     summary: Number of Cats in the United States from Feral cats: Their role in the population dynamics of Felis catus A review of the housing requirements of domestic cats (Felis silvestris catus) kept in the home Associations among weight loss, stress, and upper respiratory tract infection in shelter cats They'd Never Do It to You: A Study by Fundación Affinity Into the Abandonment and Adoption of Pets in Spain in 2018: Interpretation of Results A survey of cat shelters in Sweden Shelters reflect but cannot solve underlying problems with relinquished and stray animals-a retrospective study of dogs and cats entering and leaving shelters in Denmark from Is there a relationship between attitudes of shelter staff to cats and the cats' approach behaviour? In these countries, shelter cats can only be euthanised for medical reasons.
    keywords: animal; animal welfare; assessment; behaviour; body; cats; condition; cortisol; evaluation; feline; health; housing; indicators; life; quality; scale; score; shelter; shelter cats; stress; study; time; tool; use; welfare
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        item: #41 of 50
          id: cord-332085-s58sd8e4
      author: Wissmath, B.
       title: Understanding the psychological impact of the COVID-19 pandemic and containment measures: an empirical model of stress.
        date: 2020-05-16
       words: 2060
      flesch: 50
     summary: Individual, economic, and societal worries are also expected to increase stress levels. A onesample Gauss test showed higher stress levels during the lockdown period, z=19.08, p <.001.
    keywords: individuals; measures; preprint; stress
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        item: #42 of 50
          id: cord-333224-grjbz5u7
      author: Effati-Daryani, Fatemeh
       title: Depression, stress, anxiety and their predictors in Iranian pregnant women during the outbreak of COVID-19
        date: 2020-09-22
       words: 4693
      flesch: 45
     summary: Matern Child Health Uptrend in distress and psychiatric symptomatology in pregnant women during the coronavirus disease 2019 pandemic Effects of the COVID-19 pandemic on anxiety and depressive symptoms in pregnant women: a preliminary study The short-form version of the depression anxiety stress scales (DASS-21): construct validity and normative data in a large nonclinical sample Psychometric properties of the depression anxiety stress Scales-21 (DASS-21) in a non-clinical Iranian sample The 21-item and 12-item versions of the depression anxiety stress scales: psychometric evaluation in a Korean population Validation of depression anxiety and stress scale (DASS-21) for an Iranian population Association between psychological status with perceived social support in pregnant women referring to Tabriz health centers Depression, anxiety and stress in the various trimesters of pregnancy in women referring to Tabriz health centres Prevalence of pre and postpartum depression symptoms and some related factors Prevalence of depression, anxiety and stress in Yazd Correlation between marital satisfaction and depression among couples in Rafsanjan Post-partum depression, anxiety and marital satisfaction: a perspective from southeastern Nigeria Defining childbirth fear and anxiety levels in pregnant women Women's perception of husbands' support during pregnancy, labour and delivery Demographic, medical, and psychosocial predictors of pregnancy anxiety Predictors of mental health during pregnancy Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations We would like to thank authorities of Tabriz University of Medical Sciences for the scientific and ethical approval and financial support of this research. Since COVID-19 is a new phenomenon with limited information available, it may have adverse psychological effects on pregnant women.
    keywords: anxiety; covid-19; depression; spouse; stress; study; symptoms; women
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        item: #43 of 50
          id: cord-334890-7lpe8wa6
      author: Fitzgerald, Eamon
       title: Maternal influences on fetal brain development: the role of nutrition, infection and stress, and the potential for intergenerational consequences
        date: 2020-09-10
       words: 3569
      flesch: 13
     summary: Offspring exposed to high levels of prenatal maternal stress or anxiety are at a higher risk of developing depression 66 , ASD 67 , schizophrenia 68 and ADHD 69 as well as various emotional and behavioural problems 70 ; with the timing of stress and the sex of the fetus playing important roles in the outcome of these studies. Maternal stress can occur as a result of a diverse range of environmental perturbations and crucially, the experience of stress is highly individually specific.
    keywords: brain; effects; exposure; infection; offspring; pregnancy; risk; stress; studies
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        item: #44 of 50
          id: cord-340128-qxkopvot
      author: Schreibauer, Elena Christina
       title: Work-Related Psychosocial Stress in Small and Medium-Sized Enterprises: An Integrative Review
        date: 2020-10-13
       words: 6976
      flesch: 43
     summary: Data of included studies were analyzed and mapped into five themes: “work content and task”, “organization of work”, “social relations”, “working environment” and “new forms of work”. However, it was not suitable for a classic systematic review design and resulted in a heterogeneous sample of included studies and a high number of irrelevant hits, particularly in the database Business Source Premiere which identified numerous entries on financial stress not related to our research objective.
    keywords: enterprises; factors; health; new; psychosocial; review; smes; stress; studies; study; work; working
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        item: #45 of 50
          id: cord-342047-pm3i54mb
      author: Du Preez, Andrea
       title: The type of stress matters: repeated injection and permanent social isolation stress in male mice have a differential effect on anxiety- and depressive-like behaviours, and associated biological alterations
        date: 2020-09-21
       words: 8842
      flesch: 27
     summary: Mice were exposed to one of four experimental conditions after an initial 1week habituation period: (i) stress-free control group (socially-housed in pairs and injection naive-Group 1); (ii) repeated injection stress (sociallyhoused in pairs and repeatedly injected-Group 2); (iii) social isolation stress (permanent social isolation and injection naive-Group 3); and (iv) combined stress (permanent isolation and repeatedly injected-Group 4). We first assessed the behavioural effects associated with chronic stress exposure and found that all stress-exposed mice, irrespective of the type of stress, exhibited significantly increased anxiety-like behaviour in the OFT (Fig. 2a) relative to control animals, as shown by significantly less time in the centre of the OFT arena (−59% in repeatedly injected animals, −92% in the socially isolated mice and −74% in animals exposed to combined stress spent (Fig. 2a) ).
    keywords: animals; anxiety; cell; changes; chronic; density; depression; exposure; fig; iba1; injection; isolation; levels; mice; neurogenesis; research; stress
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        item: #46 of 50
          id: cord-347816-e2xkzps9
      author: Wesemann, U.
       title: Influence of COVID-19 on general stress and posttraumatic stress symptoms among hospitalized high-risk patients
        date: 2020-08-14
       words: 1165
      flesch: 49
     summary: key: cord-347816-e2xkzps9 authors: Wesemann, U.; Hadjamu, N.; Willmund, G.; Dolff, S.; Vonderlin, N.; Wakili, R.; Vogel, J.; Rassaf, T.; Siebermair, J. title: Influence of COVID-19 on general stress and posttraumatic stress symptoms among hospitalized high-risk patients date: 2020-08-14 journal: Psychological medicine DOI: 10.1017/s0033291720003165 sha: doc_id: 347816 cord_uid: e2xkzps9 nan To the Editor: A recently published study found a 96.2% prevalence rate for significant posttraumatic stress symptoms in quarantined patients diagnosed with COVID-19 (Bo et al., 2020) . Thereby, the rates for posttraumatic stress disorder (PTSD) in COVID-19 affected patients appear higher when compared to PTSD rates in the general population or in emergency service staff after terrorist attacks (11% to 25%; Berninger et al. 2010; Brackbill, Hadler, DiGrande, Ekenga, & Farfel, 2009; Schlenger et al. 2002; Wesemann et al., 2018b; Wesemann, Mahnke, Polk, & Willmund, 2020) .
    keywords: covid-19; patients; stress
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        item: #47 of 50
          id: cord-349219-tl97bj42
      author: Rayhan Arusha, Anowara
       title: Prevalence of Stress, Anxiety and Depression due to Examination in Bangladeshi Youths: A Pilot Study
        date: 2020-07-18
       words: 3603
      flesch: 38
     summary: Results indicated that youths with higher anxiety level perceived their mothers and fathers as being more socially isolating, more concerned about others' opinions, more ashamed of the students' shyness and poor performance, and less socially active than youths with low anxiety level (Caster et al., 1999) . Higher levels of examination anxiety were observed for students who lived without their family compared to those who lived with their family.
    keywords: anxiety; bangladesh; depression; examination; factors; health; stress; students; study
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        item: #48 of 50
          id: cord-352465-n746e8qt
      author: Wang, Fei
       title: Targeting stress granules: A novel therapeutic strategy for human diseases
        date: 2020-08-16
       words: 9163
      flesch: 35
     summary: TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis Stress granules and cell signaling: more than just a passing phase? Cap-dependent, scanning-free translation initiation mechanisms Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase Stress granules: the Tao of RNA triage Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells Kinase-mediated Phosphorylation of Eukaryotic Translation Initiation Factor 2 Inhibits Translation, Induces Stress Granule Formation, and Mediates Survival upon Arsenite Exposure Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response Stressful initiations Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation Hippuristanol-A potent steroid inhibitor of eukaryotic initiation factor 4A Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation Eukaryotic Initiation Factor 2α-independent Pathway of Stress Granule Induction by the Natural Product Pateamine A Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation Stress Granule Assembly Is Mediated by Prion-like Aggregation of TIA-1 The RasGAPassociated endoribonuclease G3BP assembles stress granules Unravelling the ultrastructure of stress granules and associated P-bodies in human cells Principles and Properties of Stress Granules Liquid phase condensation in cell physiology and disease Distinct stages in stress granule assembly and disassembly P bodies promote stress granule assembly in Saccharomyces cerevisiae Possible Roles in the Control of Translation and mRNA Degradation Eukaryotic stress granules are cleared by granulophagy and Cdc48/VCP function A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism Stress granules: sites of mRNA triage that regulate mRNA stability and translatability Dynein and kinesin regulate stressgranule and P-body dynamics Translation inhibition and stress granules in the antiviral immune response Stress granules and neurodegeneration The involvement of stress granules in aging and aging-associated diseases Stress granule: A promising target for cancer treatment Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease Differences between acute and chronic stress granules, and how these differences may impact function in human disease Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules The chemotherapeutic agent bortezomib induces the formation of Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways RhoA/ROCK1 signaling regulates stress granule formation and apoptosis Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation Regulation of stress granules in virus systems Mammalian Orthoreovirus Particles Induce and Are Recruited into Stress Granules at Early Times Postinfection Influenza A virus inhibits cytoplasmic stress granule formation Respiratory Syncytial Virus Induces Host RNA Stress Granules To Facilitate Viral Replication Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies Picornavirus 2A protease regulates stress granule formation to facilitate viral translation Stress granules (SG) and processing bodies (PB) in viral infections SARS-CoV-2 Nucleocapsid Protein Impairs SG Assembly by Partitioning into G3BP Condensate Nucleocapsid protein of SARS-CoV-2 phase separates into RNArich polymerase-containing condensates A SARS-CoV-2 protein interaction map reveals targets for drug repurposing The Global Phosphorylation Landscape of SARS-CoV-2 Infection Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases Emerging small-molecule therapeutic approaches for amyotrophic lateral sclerosis and frontotemporal dementia Converging Mechanisms in ALS and FTD: Check your RNA granule aggregation A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins A new subtype of frontotemporal lobar degeneration with FUS pathology TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA Dissecting the molecular mechanisms that impair stress granule formation in aging cells Stress granules counteract senescence by sequestration of PAI-1 DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome Activation of the integrated stress response during T helper cell differentiation Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions Presence and function of stress granules in atrial fibrillation The Kinase Inhibitor Sorafenib Induces Cell Death through a Process Involving Induction of Endoplasmic Reticulum Stress Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells Clinical Pharmacology of 5-Fluorouracil 5-Fluorouracil affects assembly of stress granules based on RNA incorporation Proteasome inhibitors in cancer therapy Psammaplysin F increases the efficacy of bortezomib and sorafenib through regulation of stress granule formation Psammaplysin F, a New Bromotyrosine Derivative from a Sponge, Aplysinella sp Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response Protein synthesis in eukaryotes: the growing biological relevance of cap-independent translation initiation The Unfolded Protein Response Triggers Selective mRNA Release from the Endoplasmic Reticulum The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly Nitric oxide triggers the assembly of type II stress granules linked to decreased cell viability Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism Malonate induces the assembly of cytoplasmic stress granules Molecular Pathways: The eIF4F Translation Initiation Complex-New Opportunities for Cancer Treatment 15-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism Translational Dysregulation by Pateamine A A comparative study of small molecules targeting eIF4A Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2 Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography One-thousand-and-one substrates of protein kinase CK2?
    keywords: apoptosis; assembly; cancer; cells; disassembly; diseases; eif2α; formation; granules; inhibitor; initiation; mrna; phosphorylation; protein; response; sgs; stress; tdp-43; translation
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        item: #49 of 50
          id: cord-353592-gsvobusu
      author: Luceño-Moreno, Lourdes
       title: Symptoms of Posttraumatic Stress, Anxiety, Depression, Levels of Resilience and Burnout in Spanish Health Personnel during the COVID-19 Pandemic
        date: 2020-07-30
       words: 7614
      flesch: 40
     summary: The protective variables of suffering posttraumatic stress symptoms are being a man, having a doctor's degree, living with a partner (not married), being a doctor or working in another position (a category made up mainly of pharmacists and psychologists), having protective equipment at work, not being concerned about infecting the people with whom they live and not living alone. The profile of a health worker with greater posttraumatic stress symptoms would be a person who works in the Autonomous Community of Madrid, in a hospital, is a woman, is concerned that a person he/she lives with may be infected, and thinks that he/she is very likely to be infected.
    keywords: anxiety; burnout; covid-19; depression; health; resilience; stress; study; symptoms; variables; workers
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        item: #50 of 50
          id: cord-356131-3at94sle
      author: MacIntyre, Peter D.
       title: Language teachers' coping strategies during the Covid-19 conversion to online teaching: Correlations with stress, wellbeing and negative emotions
        date: 2020-08-22
       words: 6620
      flesch: 46
     summary: It is important to study how these trends play out in the longer term both for language teacher stress and well-being. In addition, ANOVA showed that although approach coping was consistently used across stress groups, avoidant coping increased as stress increased suggesting that there may be a cost to using avoidant coping strategies.
    keywords: approach; coping; covid-19; language; outcomes; pandemic; strategies; stress; teachers; teaching
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