id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-272268-8vrcwwll	Kedersha, Nancy	Chapter 4 Regulation of Translation by Stress Granules and Processing Bodies	2009-10-27		.txt	text/plain	8608	294	34	The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response Disruption of microtubules inhibits cytoplasmic ribonucleoprotein stress granule formation Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules hnRNP A1 relocalization to the stress granules reflects a role in the stress response Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response Microtubuledependent association of AKAP350A and CCAR1 with RNA stress granules Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP TDRD3, a novel tudor domain-containing protein, localizes to cytoplasmic stress granules Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit Recycling of eukaryotic posttermination ribosomal complexes Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase How viruses avoid stress Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation Reovirus induces and benefits from an integrated cellular stress response Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies Interactions between brome mosaic virus RNAs and cytoplasmic processing bodies Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules A micrococcal nuclease homologue in RNAi effector complexes Inosine-containing dsRNA binds a stress-granule-like complex and downregulates gene expression in trans LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNAi RISC Retrotransposons revisited: the restraint and rehabilitation of parasites Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly Activation of the integrated stress response during T helper cell differentiation A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay Prolonged translation arrest in reperfused hippocampal cornu Ammonis 1 is mediated by stress granules Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules Post-translational arginylation of calreticulin: a new isospecies of calreticulin component of stress granules Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs Identification of FUSE-binding proteins as interacting partners of TIA proteins The cold-inducible RNAbinding protein migrates from the nucleus to cytoplasmic stress granules by a methylationdependent mechanism and acts as a translational repressor The eIF4G-homolog p97 can activate translation independent of caspase cleavage MBNL1 associates with YB-1 in cytoplasmic stress granules The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3 The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay Regulation of stress granule dynamics by Grb7 and FAK signalling pathway Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response Functional dissection of the human TNRC6 (GW182-related) family of proteins Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments Stress granule assembly is mediated by prion-like aggregation of TIA-1 HuR binding to cytoplasmic mRNA is perturbed by heat shock Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs Intracellular localization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci Identification of novel argonaute-associated proteins Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP Inhibition of G(1) to S phase progression by a novel zinc finger protein P58(TFL) at P-bodies Identification of PatL1, a human homolog to yeast P body component Pat1 Selective localization of PCBP2 to cytoplasmic processing bodies Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1 Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules Rpp 20 interacts with SMN and is re-distributed into SMN granules in response to stress The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs Sam68 functions in nuclear export and translation of HIV-1 RNA SGNP: an essential Stress Granule/Nucleolar Protein potentially involved in 5.8s rRNA processing/transport Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes Mammalian Staufen 1 is recruited to stress granules and impairs their assembly Survival motor neuron protein facilitates assembly of stress granules Probing the mRNA processing body using protein macroarrays and autoantigenomics ZBP1 regulates mRNA stability during cellular stress A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2a to the assembly of mammalian stress granules Cytoplasmic heat shock granules are formed from precursor particles and are associated with a specific set of mRNAs Plant stress granules and mRNA processing bodies are distinct from heat stress granules Mammalian stress granules: highly dynamic sites of mRNA triage during stress induced translational arrest TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation Stressful initiations Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes The RasGAPassociated endoribonuclease G3BP assembles stress granules Rasputin, more promiscuous than ever: a review of G3BP MK2-induced tristetraprolin: 14-3-3 complexes prevent stress granule association and ARE-mRNA decay Inhibition of eukaryotic translation initiation by the marine natural product pateamine A RNAmediated sequestration of the RNA helicase eIF4A by pateamine A inhibits translation initiation Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation An antiviral response directed by PKR phosphorylation of the RNA helicase A Decapping and decay of messenger RNA occur in cytoplasmic processing bodies Cytoplasmic foci are sites of mRNA decay in human cells P bodies: at the crossroads of post-transcriptional pathways P bodies and the control of mRNA translation and degradation The highways and byways of mRNA decay The control of mRNA decapping and P-body formation Perk is essential for translational regulation and cell survival during the unfolded protein response Signal integration via PKR The exonjunction-complex-component metastatic lymph node 51 functions in stress-granule assembly Distinctive properties of the 5'-untranslated region of human hsp70 mRNA Mammalian stress granules and processing bodies Translational control is required for the unfolded protein response and in vivo glucose homeostasis Metazoan stress granule assembly is mediated by P-eIF2 {alpha}-dependent and -independent mechanisms Heme-regulated inhibitor (HRI) kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 (eIF2) inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae P bodies promote stress granule assembly in Saccharomyces cerevisiae Robust heat shock induces eIF2{alpha}-phosphorylation-independent assembly of stress granules containing eIF3 and 40S ribosomal subunits in budding yeast, Saccharomyces cerevisiae Stress granules and processing bodies are dynamically linked sites of mRNP remodeling Subnuclear organelles: new insights into form and function The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly Dynein motor contributes to stress granule dynamics in primary neurons	cache/cord-272268-8vrcwwll.txt	txt/cord-272268-8vrcwwll.txt
