item: #1 of 50 id: cord-006182-kck5e1ry author: None title: 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date: 2019-10-01 words: 87787 flesch: 45 summary: Whether a laboratory response in coagulation dosing, laboratory response, hemostatic efficacy and patient outcomes. A project aimed at improving DI management through predictive assessments and DDAVP protocols could potentially improve patient outcomes. keywords: acute; admission; adult patients; analysis; arrest; arrest patients; asah; associated; association; baseline; blood; brain; brain injury; cardiac; care; case; center; cerebral; changes; cohort; common; complications; data; days; dci; death; diagnosis; difference; discharge; disease; dose; edema; eeg; factors; functional; gcs; group; hemorrhage; higher; hospital; hours; ich patients; icp; icu; imaging; improvement; initial; injury; intervention; intracranial; ischemic; left; levels; management; mean; median; medical; monitoring; mortality; mri; mrs; neurocritical; new; non; outcome; patients; post; pressure; primary; rate; related; results; review; risk; sah; sah patients; scale; score; seizures; status; stroke; stroke patients; studies; study; subarachnoid; tbi patients; test; therapeutic; therapy; time; total; treatment; ttm; unit; use; vasospasm; years cache: cord-006182-kck5e1ry.txt plain text: cord-006182-kck5e1ry.txt item: #2 of 50 id: cord-006870-f5w6fw6q author: None title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 words: 122395 flesch: 46 summary: The best model fit was for good outcome (modified Rankin Score 0-2 equivalents) based on % patients with WFNS 4-5 and age (R2=0.54; p<0.001). Decreasing time spent in cervical spinal immobilization could improve patient care by allowing greater access to / range-of-motion of the neck, increasing patient comfort, and decreasing skin breakdown. keywords: acute; administration; admission; adult patients; analysis; arrest; asah; associated; baseline; blood; brain; brain injury; cardiac; care patients; care unit; case; center; cerebral; cohort; common; complications; data; days; death; diagnosis; difference; discharge; duration; early; edema; eeg; effect; epilepticus; evd; factors; findings; following; gcs; group; head; hematoma; hemorrhage; hemorrhage patients; hospital; hours; ich; ich patients; icp; icu; identified; imaging; improvement; infusion; initial; injury; intracerebral; intracranial; ischemic; left; level; los; management; mean; median; medical; minutes; model; monitoring; months; mortality; mri; neurocritical; new; non; number; outcome; patients; period; placement; population; post; presence; present; pressure; primary; prior; prospective; rate; refractory; related; report; results; review; right; risk; risk patients; sah patients; scale; score; secondary; seizures; srse; status; stay; stroke patients; studies; study; subarachnoid; surgery; tbi; tbi patients; test; therapy; time; total; treatment; unit; use; years cache: cord-006870-f5w6fw6q.txt plain text: cord-006870-f5w6fw6q.txt item: #3 of 50 id: cord-010977-fwz7chzf author: Myserlis, Pavlos title: Translational Genomics in Neurocritical Care: a Review date: 2020-02-20 words: 12007 flesch: 21 summary: Given that diseases common to the neurocritical care population so rarely afford access to brain tissue for pathologic or genomic analysis antemortem, model system genomic studies offer an important adjunct for translational research. As such, many model system studies start with RNA, examining how the genome responds to perturbation through the transcriptome. keywords: animal; approach; brain; care; disease; expression; gene; genome; genomic; hemorrhage; human; injury; mechanisms; models; patients; research; risk; sequencing; stroke; studies; study; systems; tbi; translational; variants cache: cord-010977-fwz7chzf.txt plain text: cord-010977-fwz7chzf.txt item: #4 of 50 id: cord-011483-zc6ve6le author: Leclerc, Angela M. title: Amantadine and Modafinil as Neurostimulants Following Acute Stroke: A Retrospective Study of Intensive Care Unit Patients date: 2020-05-20 words: 5734 flesch: 40 summary: This study represents the largest cohort of stroke patients treated with neurostimulants during their acute hospitalization, and suggests amantadine started in the first week after stroke may be associated with improved wakefulness or responsiveness in approximately half of treated patients. Due to the paucity of published data for stroke patients treated with neurostimulants in the acute setting, no protocols or robust data were available to guide us or allow for a power calculation. keywords: acute; administration; amantadine; modafinil; n =; neurostimulant; patients; rehabilitation; stroke; study cache: cord-011483-zc6ve6le.txt plain text: cord-011483-zc6ve6le.txt item: #5 of 50 id: cord-016906-ynfb10pq author: Tang, Yaohui title: Modification of Bone Marrow Stem Cells for Homing and Survival During Cerebral Ischemia date: 2016-12-15 words: 9901 flesch: 22 summary: Therefore, cell-ECM interactions are reduced, and apoptosis is initiated even prior to transplantation when stem cells are trypsinized as single cells, cell survival is further reduced by needle insertion, and growth factors withdraw during the injection process, as well as hostile environment they confront in the lesion site after transplantation, given the generation of reactive oxygen species (ROS) and inflammatory response mediators in brain postischemia. [110] , and our in vitro studies also suggested that exposure of stem cells to culture conditions which mimic the hostile environment in vivo (such as oxygen-glucose deprivation and H2O2 stimulation) led to the apoptosis mediated by ROS [110] . keywords: bone; brain; cells; cerebral; growth; homing; human; ischemic; marrow; mesenchymal; migration; mscs; neural; progenitor; stem; stem cells; stroke; stromal; survival; transplantation cache: cord-016906-ynfb10pq.txt plain text: cord-016906-ynfb10pq.txt item: #6 of 50 id: cord-027259-f4sgobcz author: Metsker, Oleg title: Stroke ICU Patient Mortality Day Prediction date: 2020-05-23 words: 5336 flesch: 38 summary: According to the findings of a large-scale study of recent years, some modern epidemiological trends have been identified [3] : In general, global statistics show a decline in stroke mortality over the past two decades due to the introduction of new treatments (thrombolysis, thrombectrosis), but the absolute number of people who have stroke is only increasing every year The unmodifiable factors of stroke mortality include: gender, age, type of stroke, localization of lesion. keywords: brain; data; days; hospital; hospital mortality; ischemic; models; mortality; patients; rate; stroke; subgroups cache: cord-027259-f4sgobcz.txt plain text: cord-027259-f4sgobcz.txt item: #7 of 50 id: cord-032820-l0vkq0j3 author: Mohamed, Sherif title: Incidence and pathophysiologic mechanisms of stroke in the COVID-19 pandemic: the dilemma date: 2020-09-29 words: 1626 flesch: 49 summary: WHO coronavirus disease (COVID-19) dashboard Neurologic manifestations of hospitalized patients with coronavirus disease Risk of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) vs patients with influenza EXPRESS: COVID-19 and stroke-a global World Stroke Organization perspective The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients SARS-CoV-2 and stroke in a New York Healthcare System The baffling case of ischemic stroke disappearance from the casualty department in the COVID-19 era Anticytokine agents targeting interleukin signaling pathways for the treatment of atherothrombosis Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Cerebrovascular disease is associated with an increased disease severity in patients with coronavirus disease 2019 (COVID-19): a pooled analysis of published literature Large-vessel stroke as a presenting feature of Covid-19 in the young Management of acute ischemic stroke in patients with COVID-19 infection: insights from an international panel On being a neurologist in Italy at the time of the COVID-19 outbreak Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Not applicable Availability of data and materials Not applicable Ethics approval and consent to participate Not applicable. The COVID-19 pandemic has, in different ways, negative impacts on care of stroke patients worldwide, and still, many challenges are faced by neurologists to improve care of stroke patients during such crisis. keywords: covid-19; pandemic; patients; stroke cache: cord-032820-l0vkq0j3.txt plain text: cord-032820-l0vkq0j3.txt item: #8 of 50 id: cord-034257-kl2ccmz5 author: de Jonge, Jeroen C. title: PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke—statistical analysis plan of a randomised, open, phase III, clinical trial with blinded outcome assessment date: 2020-10-26 words: 3734 flesch: 47 summary: Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment Contemporary outcome measures in acute stroke research Improving the efficiency of stroke trials Statistical analysis of the primary outcome in acute stroke trials Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations None. Medical complications after stroke Characteristic adverse events and their incidence among patients participating in acute ischemic stroke trials Development and internal validation of a prediction rule for post-stroke infection and poststroke pneumonia in acute stroke patients Post-stroke infection: a systematic review and meta-analysis Therapeutic hypothermia in acute ischemic stroke Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis Effect of hyperthermia on prognosis after acute ischemic stroke Dysphagia after stroke: incidence, diagnosis, and pulmonary complications Temporal profile of body temperature in acute ischemic stroke: relation to infarct size and outcome Poststroke dysphagia: a review and design considerations for future trials Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial An early rise in body temperature is related to unfavorable outcome after stroke: data from the PAIS study Antibiotic therapy for preventing infections in patients with acute stroke The Paracetamol (Acetaminophen) keywords: analysis; data; days; mrs; outcome; patients; stroke; treatment; trial cache: cord-034257-kl2ccmz5.txt plain text: cord-034257-kl2ccmz5.txt item: #9 of 50 id: cord-103915-rzy7mejb author: Duricki, Denise A. title: Corticospinal neuroplasticity and sensorimotor recovery in rats treated by infusion of neurotrophin-3 into disabled forelimb muscles started 24 h after stroke date: 2018-07-11 words: 12878 flesch: 48 summary: However, ELISA cannot distinguish exogenous human NT3 from endogenous rat NT3 because the amino acid sequences for mature human and rat NT3 are identical 58,59 . Because ELISA did not allow us to detect any small increases in exogenous human NT3 against the background of endogenous rat NT3 in the CNS, we next used a more sensitive method for measuring trafficking of NT3 across the blood-CNS barrier. keywords: brain; cord; cst; fig; forelimb; group; human; muscle; nerve; neurotrophin-3; nt3; protein; rats; recovery; spinal; stimulation; stroke; time; treatment; triceps; vehicle; weeks; wrist cache: cord-103915-rzy7mejb.txt plain text: cord-103915-rzy7mejb.txt item: #10 of 50 id: cord-133894-wsnyq01s author: Arora, Rahul title: Mid-Air Drawing of Curves on 3D Surfaces in AR/VR date: 2020-09-18 words: 12039 flesch: 60 summary: e limitations of context-free projection can be addressed by equipping stroke point projection with the context/history of recently drawn points and their projections. We present the first detailed investigation of the fundamental problem of 3D stroke projection in AR/VR. keywords: air; controller; curve; drawing; et al; figure; mid; mimicry; object; point; projection; spraycan; stroke; surface; user cache: cord-133894-wsnyq01s.txt plain text: cord-133894-wsnyq01s.txt item: #11 of 50 id: cord-252687-7084pfqm author: Szelenberger, Rafal title: Ischemic Stroke among the Symptoms Caused by the COVID-19 Infection date: 2020-08-19 words: 7350 flesch: 34 summary: Despite the available clinical studies evaluating the potential role of hemostatis biomarkers (i.e., von Willebrand factor (vWF), P-selectin, fibrinogen, thrombomodulin, tissue factor, d-dimer, etc.) in ischemic stroke patients, the value of studied biomarkers is still unproven and requires further investigation [26] . Ischemic stroke patients mostly received thrombolytic therapy. keywords: acute; blood; brain; cells; coagulation; coronavirus; cov-2; covid-19; endothelium; infection; ischemic; patients; response; sars; stroke; symptoms; system cache: cord-252687-7084pfqm.txt plain text: cord-252687-7084pfqm.txt item: #12 of 50 id: cord-254423-jz6hoxk1 author: Song, Lili title: Impact of COVID-19 on Patient Behavior to Stroke Symptoms in China date: 2020-10-08 words: 746 flesch: 38 summary: Collateral effect of COVID-19 on stroke evaluation in the United States Clinical guide for the management of stroke patients during the coronavirus pandemic C.S.A. holds a Senior Investigator Fellowship of the National Health and Medical Research Council of Australia and reports honoraria and travel reimbursement and grants from Takeda, China. Although various clinical guidelines for the management of stroke during the COVID-19 pandemic have been released [4] , additional efforts are needed to reassure the population and encourage people to seek rapid access to stroke services in order to receive essential interventions. keywords: covid-19; patients; stroke cache: cord-254423-jz6hoxk1.txt plain text: cord-254423-jz6hoxk1.txt item: #13 of 50 id: cord-255604-hnbzidf3 author: Liu, Liping title: Approaches to global stroke care during the COVID-19 pandemic date: 2020-05-23 words: 1265 flesch: 54 summary: 4 5 Realising this challenge and urgency, the Chinese Stroke Association convened a group of international stroke leaders and discussed the challenges facing stroke care worldwide and recommendations of stroke care during the COVID-19 pandemic. 6 COVID-19 will thus likely change our way of delivering stroke care for years to come. keywords: care; covid-19; patients; stroke cache: cord-255604-hnbzidf3.txt plain text: cord-255604-hnbzidf3.txt item: #14 of 50 id: cord-257074-baiqcoao author: Bersano, Anna title: The impact of SARS‐Cov‐2 pandemic on stroke care: A warning message date: 2020-06-11 words: 542 flesch: 33 summary: key: cord-257074-baiqcoao authors: Bersano, Anna; Pantoni, Leonardo title: The impact of SARS‐Cov‐2 pandemic on stroke care: A warning message date: 2020-06-11 journal: Eur J Neurol DOI: 10.1111/ene.14394 sha: doc_id: 257074 cord_uid: baiqcoao The recent coronavirus disease (COVID‐19) pandemic intensely impacted the health systems worldwide, which had to deal with the challenge of contemporarily answering to the needs of COVID‐19 patients and managing other life threatening disorders. Although other observations on stroke care changes have been published, most of them lack of systemic information, due to the difficulty in data collection in this challenging time. keywords: covid-19; stroke cache: cord-257074-baiqcoao.txt plain text: cord-257074-baiqcoao.txt item: #15 of 50 id: cord-257433-qgkwylmk author: Candeloro, Elisa title: An Example of a Stroke Unit Reshaping in the Context of a Regional Hub and Spoke System in the COVID-19 Era date: 2020-10-15 words: 3563 flesch: 51 summary: Our data showed that despite the fact that the COVID-19 pandemic imposed a reallocation of health system resources, largely toward the management of COVID-19 patients, we were still able to guarantee a timely and safe approach for stroke patients. This is because most of the resources normally available in hospitals had to be devoted to the treatment of COVID-19 patients. keywords: covid-19; door; hospital; patients; period; stroke; time cache: cord-257433-qgkwylmk.txt plain text: cord-257433-qgkwylmk.txt item: #16 of 50 id: cord-259845-kjbhmsqr author: Morelli, Nicola title: COVID-19-Related Stroke: Barking up the Wrong Tree? date: 2020-06-11 words: 640 flesch: 47 summary: The Case Is Much More Baffling than We Think Large-vessel stroke as a presenting feature of Covid-19 in the young Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Neurologic features in severe SARS-CoV-2 infection Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Acute ischemic stroke complicating common carotid artery thrombosis during a severe COVID-19 infection Could COVID-19 represent a negative prognostic factor in patients with stroke? In the following period, only few small case series of COVID-19 stroke patients have been reported [3] [4] [5] keywords: covid-19; stroke cache: cord-259845-kjbhmsqr.txt plain text: cord-259845-kjbhmsqr.txt item: #17 of 50 id: cord-267402-kca05rvz author: South, Kieron title: Preceding infection and risk of stroke: An old concept revived by the COVID-19 pandemic date: 2020-07-24 words: 6252 flesch: 31 summary: medRxiv, Epub ahead of print 2020 Dysregulation of Immune Response in Patients With Coronavirus Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome Clinical progression and cytokine profiles of middle east respiratory syndrome coronavirus infection Inflammatory cytokines and ischemic stroke risk: the REGARDS cohort Systemic infections cause exaggerated local inflammation in atherosclerotic coronary arteries: clues to the triggering effect of acute infections on acute coronary syndromes Inflammation and plaque vulnerability Infection and atherosclerosis development The role of immune cells in atrial fibrillation The role of infection in the development of non-valvular atrial fibrillation: up-regulation of Toll-like receptor 2 expression levels on monocytes Pandemic H1N1 influenza infection and vascular thrombosis Pulmonary artery thrombosis in a patient with severe acute respiratory syndrome Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Hypercoagulability of COVID-19 patients in intensive care unit: A report of thromboelastography findings and other parameters of hemostasis Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in C-reactive protein levels in the early stage of COVID-19 Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury Thrombinactivatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand factor multimers under flow Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells Inflammationassociated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor Acute respiratory tract infection leads to procoagulant changes in human subjects Analysis of thrombotic factors in severe acute respiratory syndrome (SARS) patients Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS-CoV-2 Epub ahead of print 23 ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women High levels of von Willebrand factor and low levels of its cleaving protease, ADAMTS13, are associated with stroke in young HIVinfected patients Thrombocytopenia and its association with mortality in patients with COVID-19 Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With COVID-19 Platelets and infection -an emerging role of platelets in viral infection Neutrophil extracellular traps in COVID-19 ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice Hypercoagulability is a stronger risk factor for ischaemic stroke than for myocardial infarction: a systematic review Severe COVID-19 infection associated with endothelial activation Electron microscopy of SARS-CoV-2: a challenging task -authors' reply Aberrant coagulation causes a hyper-inflammatory response in severe influenza pneumonia Immunopathogenesis of coronavirus infections: implications for SARS Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease Central nervous system manifestations of COVID-19: a systematic review Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Central nervous system infections and stroke -a population-based analysis The neutrophil in vascular inflammation COVID-19 and cardiovascular disease Defining causality in COVID-19 and neurological disorders Thromboprophylaxis in intensive care unit patients: a literature review Risk of Ischemic Stroke in Patients with Covid-19 versus Patients with Influenza Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Coronavirus Infections and Type 2 Diabetes-Shared Pathways with Therapeutic Implications Obesity and impaired metabolic health in patients with COVID-19 Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California Increased risk of influenza among vaccinated adults who are obese Obesity, inflammation, and insulin resistance -a mini-review Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation Chest CT findings in cases from the cruise ship 'Diamond Princess' with coronavirus disease 2019 (COVID-19) Association between influenza vaccination and reduced risk of brain infarction Management of acute ischemic stroke in patients with COVID-19 infection: report of an international panel There is clear evidence, from post-mortem lung pathology, of extensive thrombosis in the alveolar capillaries and small vessels in response to COVID-19 infection. keywords: acute; cells; coronavirus; cov-2; covid-19; disease; factor; incidence; infection; patients; risk; sars; stroke cache: cord-267402-kca05rvz.txt plain text: cord-267402-kca05rvz.txt item: #18 of 50 id: cord-270475-mkpn9tz6 author: Requena, Manuel title: COVID-19 and Stroke: incidence and etiological description in a high-volume center. date: 2020-08-05 words: 2428 flesch: 42 summary: Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist. Our aim is to uncover the rate of acute stroke in COVID-19 patients admitted in a highvolume center and identify those cases in which a possible causative relationship could exist. keywords: covid-19; hospital; infection; patients; risk; sars; stroke cache: cord-270475-mkpn9tz6.txt plain text: cord-270475-mkpn9tz6.txt item: #19 of 50 id: cord-271168-a9sf8f4p author: Montaner, Joan title: Break in the Stroke Chain of Survival Due to COVID-19 date: 2020-06-08 words: 3976 flesch: 48 summary: We wondered how the measures aimed at COVID-19 are changing the way stroke patients are treated and observed that the growing pandemic had produced a reduction in the number of acute stroke patients that come into our healthcare system. In conclusion, huge collateral damage to acute stroke patients is occurring during the COVID-19 pandemic. keywords: acute; cases; covid-19; hospitals; number; outbreak; patients; stroke cache: cord-271168-a9sf8f4p.txt plain text: cord-271168-a9sf8f4p.txt item: #20 of 50 id: cord-274810-vfr1g9kp author: Lee, Meng title: Covert COVID-19 complications: Continuing the use of evidence-based drugs to minimize potentially lethal indirect effects of the pandemic in stroke patients date: 2020-05-06 words: 753 flesch: 31 summary: The safety advantage for novel oral anticoagulants over warfarin may be even larger during the J o u r n a l P r e -p r o o f Journal Pre-proof COVID-19 pandemic, because it will be challenging for stroke patients with atrial fibrillation who take warfarin to receive regular blood tests to monitor international normalized ratios, and therefore it may be prudent to prescribe novel oral anticoagulants instead of warfarin to stroke patients with atrial fibrillation during this crisis period. 2 It would be a disaster if stroke patients cannot continuously take their prescribed antithrombotic agent during this pandemic. keywords: patients; stroke cache: cord-274810-vfr1g9kp.txt plain text: cord-274810-vfr1g9kp.txt item: #21 of 50 id: cord-277011-0khsxhwv author: Aguiar de Sousa, Diana title: Stroke care in Europe during the COVID‐19 pandemic date: 2020-06-16 words: 648 flesch: 47 summary: In their report the authors offer an international perspective on the modifications in stroke care during the pandemic and provide insight into differences between countries in policy measures and in challenges faced by stroke care providers. key: cord-277011-0khsxhwv authors: Aguiar de Sousa, Diana; van der Worp, H. Bart title: Stroke care in Europe during the COVID‐19 pandemic date: 2020-06-16 journal: keywords: care; stroke cache: cord-277011-0khsxhwv.txt plain text: cord-277011-0khsxhwv.txt item: #22 of 50 id: cord-280733-d44se0v3 author: Aguiar de Sousa, Diana title: Maintaining stroke care in Europe during the COVID-19 pandemic: Results from an international survey of stroke professionals and practice recommendations from the European Stroke Organisation date: 2020-06-10 words: 3058 flesch: 44 summary: Two hundred sixty-six European participants (71%) estimated that functional outcomes and recurrence rates of stroke patients would be affected by the changes in stroke care related to the COVID-19 outbreak. Only 21% of respondents considered that, in their centres, all stroke patients were still receiving the usual acute and post-acute care, and more than 70% estimated that functional outcomes and recurrence rates of stroke patients would be affected by the changes in stroke care related with the outbreak. keywords: care; covid-19; european; health; patients; stroke; survey cache: cord-280733-d44se0v3.txt plain text: cord-280733-d44se0v3.txt item: #23 of 50 id: cord-282956-f7if9e5q author: Yaghi, Shadi title: SARS2-CoV-2 and Stroke in a New York Healthcare System date: 2020-05-26 words: 2892 flesch: 35 summary: We compared the clinical characteristics of stroke patients with a concurrent diagnosis of COVID-19 to stroke patients without COVID-19 (contemporary controls). Our study also shows that the number of COVID-19 positive ischemic strokes has increased initially but seems to have peaked and then decreased. keywords: acute; controls; covid-19; disease; patients; stroke; study cache: cord-282956-f7if9e5q.txt plain text: cord-282956-f7if9e5q.txt item: #24 of 50 id: cord-287742-y1j9x5ne author: Lee, Kai Wei title: Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis date: 2020-10-06 words: 6552 flesch: 38 summary: Ischemic stroke was the predominant stroke, and it was observed in 90.3% of stroke cases as compared to 9.7% patients presenting with hemorrhagic stroke. The following data were extracted from every study: the last name of the first author, year of publication, country, severity status, study design, patient characteristics (ethnicity composition, gender, and mean age), comorbidities (diabetes, hyperlipidemia, hypertension, ischemic heart disease, heart failure, previous stroke, chronic kidney disease/end-stage renal disease, number of stroke patients per overall participants, any information relevant to strokes such as the location of stroke [arterial or venous]), types of stroke (ischemic or haemorrhagic), classification of stroke, mortality rate, and blood parameters. keywords: analysis; coronavirus; covid-19; data; disease; infection; ischemic; meta; patients; review; risk; stroke; studies cache: cord-287742-y1j9x5ne.txt plain text: cord-287742-y1j9x5ne.txt item: #25 of 50 id: cord-288634-7g2kg2tz author: Bres Bullrich, Maria title: COVID-19: Stroke Admissions, Emergency Department Visits, and Prevention Clinic Referrals date: 2020-05-26 words: 1781 flesch: 47 summary: 1,2 However, to date, no study has formally evaluated the impact of the coronavirus disease 19 (COVID-19) pandemic on the number of stroke patients being assessed in the ED, stroke admissions, or referrals to stroke prevention clinics in Canada. To compare code strokes, stroke unit admissions, and clinic referrals in 2020 against 2019, we plotted weekly numbers of consults in both years. keywords: clinic; number; referrals; stroke cache: cord-288634-7g2kg2tz.txt plain text: cord-288634-7g2kg2tz.txt item: #26 of 50 id: cord-290216-kui8g3w6 author: Balestrino, Maurizio title: Request of hospital care dropped for TIA but remained stable for stroke during COVID-19 pandemic at a large Italian university hospital date: 2020-10-15 words: 2126 flesch: 51 summary: While decrease in stroke incidence and fear of patients to go to the hospitals were sometimes invoked to explain this decrease, reduction in urban pollution was also hypothesized as a possible cause. Several papers reported decreased stroke incidence during the current COVID-19 pandemic [1] [2] keywords: decrease; hospital; ischemic; pandemic; stroke cache: cord-290216-kui8g3w6.txt plain text: cord-290216-kui8g3w6.txt item: #27 of 50 id: cord-291413-cgec7150 author: Al-Jehani, Hosam title: MENA-SINO Consensus Statement on Implementing Care Pathways for Acute Neurovascular Emergencies During the COVID-19 Pandemic date: 2020-08-25 words: 3767 flesch: 44 summary: Published and anecdotal reports suggest that during the pandemic, there has been a drastic reduction in the number of stroke patients being evaluated in the emergency room (ER) or being admitted to hospitals worldwide (6) . In theory, monitored anesthesia care (MAC) may prevent intense aerosolization; however, stroke patients undergoing MAC sedation may require supplemental oxygen via a nasal cannula mask or other methods, such as chin-lift or jaw thrust maneuvers, to improve oxygenation, which may increase the degree of airborne exposure to the anesthesia provider and other involved HCWs. keywords: care; challenges; covid-19; medical; pandemic; patients; stroke cache: cord-291413-cgec7150.txt plain text: cord-291413-cgec7150.txt item: #28 of 50 id: cord-294139-78c5h7la author: Yamakawa, Mai title: Clinical Characteristics of Stroke with COVID-19: A Systematic Review and Meta-Analysis date: 2020-08-29 words: 3100 flesch: 38 summary: Forest plots for characteristics of stroke patients with COVID-19 (random-effects model); (A): The frequency of stroke Days from COVID-19 symptom onset to stroke; (C): D-dimer; (D): Case fatality rate Funding: None. Numerous case reports and retrospective cohort studies have been published with mixed characteristics of COVID-19 patients with stroke regarding age, comorbidities, treatment, and outcome. keywords: case; covid-19; patients; risk; stroke; studies; study cache: cord-294139-78c5h7la.txt plain text: cord-294139-78c5h7la.txt item: #29 of 50 id: cord-297512-l9re9h4j author: Sultana, Shehnaz title: Interferon gamma (IFNγ) +874A/T gene polymorphism in South Indian ischemic stroke patients date: 2011-07-17 words: 2157 flesch: 37 summary: The percentage of males among the stroke patients was 71.9% (n=123), which was higher compared to controls 52.9% (n=81), whereas the percentage of females was 28.1% (n=48) in stroke patients and 47.1% (n=72) in the control group. The percentage of hypertension was 72.5% in stroke patients and 43.7% in controls. keywords: gamma; gene; ifn; ischemic; patients; polymorphism; stroke cache: cord-297512-l9re9h4j.txt plain text: cord-297512-l9re9h4j.txt item: #30 of 50 id: cord-300742-hsfh4hw9 author: Ghoreishi, Abdoreza title: Stroke care trends during COVID-19 pandemic in Zanjan Province, Iran. From the CASCADE Initiative: statistical analysis plan and preliminary results date: 2020-09-16 words: 3961 flesch: 42 summary: The results of this research will contribute to a similar analysis of the larger CASCADE dataset in order to confirm findings at a global scale and improve measures to ensure the best quality of care for stroke patients during the COVID-19 pandemic. The results of this research will contribute to a similar analysis of the larger CASCADE dataset in order to confirm findings at a global scale and improve measures to ensure the best quality of care for stroke patients during the COVID-19 pandemic. keywords: care; changes; covid-19; hospital; pandemic; patients; rate; stroke; study; time cache: cord-300742-hsfh4hw9.txt plain text: cord-300742-hsfh4hw9.txt item: #31 of 50 id: cord-302062-wqmynngg author: Sierra-Hidalgo, Fernando title: Large artery ischemic stroke in severe COVID-19 date: 2020-06-27 words: 1147 flesch: 41 summary: key: cord-302062-wqmynngg authors: Sierra-Hidalgo, Fernando; Muñoz-Rivas, Nuria; Torres Rubio, Pedro; Chao, Kateri; Villanova Martínez, Mercedes; Arranz García, Paz; Martínez-Acebes, Eva title: Large artery ischemic stroke in severe COVID-19 date: 2020-06-27 journal: J Neurol DOI: 10.1007/s00415-020-09967-1 sha: doc_id: 302062 cord_uid: wqmynngg nan The coronavirus disease 2019 (COVID-19) pandemic has spread rapidly all around the world. Ischemic stroke occurred a median of 11.5 days after the onset of COVID-19 symptoms (interquartile range, IQR 2.8-16.3). keywords: covid-19; ischemic; patients; stroke cache: cord-302062-wqmynngg.txt plain text: cord-302062-wqmynngg.txt item: #32 of 50 id: cord-304636-houm2zcu author: Guillan, Marta title: Unusual simultaneous cerebral infarcts in multiple arterial territories in a COVID-19 patient date: 2020-06-09 words: 1091 flesch: 32 summary: The bottom row images depict axial T2 gradient echo sequences with blooming Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features Characteristics of ischaemic stroke associated with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Low Diagnostic Yield of Routine Cerebrospinal Fluid Analysis in Juvenile Stroke Central nervous system vasculitis associated with hepatitis C virus infection: a brain MRI-supported diagnosis Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis Infections causing stroke or strokelike syndromes All patients in the stroke unit have signed an informed consent to collect and use their anonymised data for research purposes. Previous studies carried out in stroke patients showed a variable range of reactive pleocytosis up to 64 Mpt/L cell and nonspecific proteins up to 1507 mg/L in CSF keywords: cases; covid-19; patients; stroke cache: cord-304636-houm2zcu.txt plain text: cord-304636-houm2zcu.txt item: #33 of 50 id: cord-307087-zsbmaieg author: Aguiar de Sousa, Diana title: The Curious Case of the Missing Strokes During the COVID-19 Pandemic date: 2020-06-08 words: 1388 flesch: 42 summary: Dr Elkind receives research support from the BMS-Pfizer Alliance for Eliquis and Roche outside the submitted work. COVID-19 and stroke -a global world stroke organization perspective Collateral effect of Covid-19 on stroke evaluation in the United States The impact of the COVID-19 epidemic on stroke care and potential solutions Acute stroke care is at risk in the era of COVID-19: experience at a comprehensive stroke center in Barcelona Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study Short term exposure to air pollution and stroke: systematic review and meta-analysis IPD-Work Consortium. Notably, the proportion of patients with stroke undergoing thrombolysis and thrombectomy remained stable, despite a 25% reduction in absolute numbers that is likely to be attributed to the drop in stroke admissions. keywords: covid-19; pandemic; patients; stroke cache: cord-307087-zsbmaieg.txt plain text: cord-307087-zsbmaieg.txt item: #34 of 50 id: cord-309227-kgrfnkns author: Coote, Skye title: Letter to the Editor regarding: Critical considerations for stroke management during COVID-19 pandemic by Inglis et al., Heart Lung Circ. 2020;29(9): 1263–1267. date: 2020-10-09 words: 485 flesch: 44 summary: CSANZ COVID-19 cardiovascular nursing care consensus statement: Executive summary COVID-19 and stroke -A global World Stroke Organization perspective Delayed presentation of acute ischemic strokes during the COVID-19 crisis Impact of the COVID-19 Epidemic on Stroke Care and Potential Solutions SSA statement of stroke care during the COVID-19 Stroke Society of Australasia Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials This de-valuing of hospital response times and services has resulted in the Stroke Society of Australasia's plea to hospital executives to protect the integrity of stroke services key: cord-309227-kgrfnkns authors: Coote, Skye; Cadilhac, Dominique A.; O’Brien, Elizabeth; Middleton, Sandy title: Letter to the Editor regarding: Critical considerations for stroke management during COVID-19 pandemic by Inglis et al., Heart Lung Circ. keywords: covid-19; stroke cache: cord-309227-kgrfnkns.txt plain text: cord-309227-kgrfnkns.txt item: #35 of 50 id: cord-309360-cpis1l4u author: Barrios-López, J. M. title: Ischaemic stroke and SARS-CoV-2 infection: A causal or incidental association? date: 2020-05-28 words: 3155 flesch: 35 summary: Materials and methods We describe the cases of 4 patients with ischaemic stroke and COVID-19 who were attended at our hospital. We also conducted a review of studies addressing the possible mechanisms involved in the aetiopathogenesis of ischaemic stroke in these patients. keywords: causal; cov-2; covid-19; hypercoagulability; ictus; infection; inflammation; patients; sars; stroke; study cache: cord-309360-cpis1l4u.txt plain text: cord-309360-cpis1l4u.txt item: #36 of 50 id: cord-310105-a4fzp6bn author: Kamdar, Hera A. title: Clinician's Perception of Practice Changes for Stroke During the COVID-19 Pandemic: Perception of Practice Changes for Stroke During COVID-19 date: 2020-07-22 words: 2120 flesch: 40 summary: Our study demonstrated the rapidly changing environment surrounding stroke patients in the era of COVID-19. Many respondents also felt that the outcome or care of stroke patients at his or her institution had been impacted by the COVID-19 pandemic. keywords: acute; care; covid-19; pandemic; patients; stroke cache: cord-310105-a4fzp6bn.txt plain text: cord-310105-a4fzp6bn.txt item: #37 of 50 id: cord-313539-fb5uzzua author: Venketasubramanian, Narayanaswamy title: Stroke in COVID-19 and SARS-CoV-1 date: 2020-05-26 words: 332 flesch: 51 summary: key: cord-313539-fb5uzzua authors: Venketasubramanian, Narayanaswamy; Hennerici, Michael G. title: Stroke in COVID-19 and SARS-CoV-1 date: 2020-05-26 journal: Cerebrovasc Dis DOI: 10.1159/000508370 sha: doc_id: 313539 cord_uid: fb5uzzua nan There has been a recent report of large artery ischaemic stroke among young patients with coronavirus disease 2019 (COVID-19) in the USA [1] . More data are needed to better understand the mechanisms and treatment of stroke during coronavirus infections, even more so as those with prior stroke have worse outcome when they develop COVID-19 keywords: stroke cache: cord-313539-fb5uzzua.txt plain text: cord-313539-fb5uzzua.txt item: #38 of 50 id: cord-315162-v3g6eios author: De Silva, Deidre Anne title: A protocol for acute stroke unit care during the COVID-19 pandemic: Acute stroke unit care during COVID-19 date: 2020-06-05 words: 1956 flesch: 44 summary: The adapted ASU pathway is a guide which has assisted care of stroke patients outside our usual ASU physical ward and pathway, and by staff not familiar with stroke patient management. Stroke patients with possible suspected COVID-19 infection may be isolated in other wards outside the ASU. keywords: asu; care; covid-19; patients; stroke cache: cord-315162-v3g6eios.txt plain text: cord-315162-v3g6eios.txt item: #39 of 50 id: cord-321461-1s3y9kc5 author: Rajdev, Kartikeya title: Acute Ischemic and Hemorrhagic Stroke in COVID-19: Mounting Evidence date: 2020-08-31 words: 2474 flesch: 42 summary: Physicians should have a low threshold for suspecting stroke in COVID-19 patients, and close observation should be kept on such patients particularly those with clinical evidence of traditional risk factors. However, treating physicians should have a low threshold for suspecting stroke in COVID-19 patients, and close observation should be kept on such patients particularly those with clinical evidence of traditional risk factors. keywords: ace2; covid-19; ischemic; patient; risk; stroke cache: cord-321461-1s3y9kc5.txt plain text: cord-321461-1s3y9kc5.txt item: #40 of 50 id: cord-322628-sh09ij0f author: Wong, Ka Sing title: Low-molecular-weight heparin compared with aspirin for the treatment of acute ischaemic stroke in Asian patients with large artery occlusive disease: a randomised study date: 2007-03-28 words: 4125 flesch: 43 summary: In hospitals where screening logs were available, we estimated that about 3·5% of acute stroke patients were eligible as per the study protocol. The mean NIHSS scores were 3·4 (SD 4·1) for LMWH and 3·6 (SD 4·3) for This trial was designed to assess the eff ects of LMWH versus aspirin on acute stroke patients with LAOD (predominantly due to intracranial atherosclerosis). keywords: acute; aspirin; laod; lmwh; outcome; patients; stroke; study; treatment; trial cache: cord-322628-sh09ij0f.txt plain text: cord-322628-sh09ij0f.txt item: #41 of 50 id: cord-326626-ixxk6plf author: Akhtar, Naveed title: Characteristics and Comparison of 32 COVID-19 and Non-COVID-19 Ischemic Strokes and historical stroke patients. date: 2020-11-02 words: 2460 flesch: 43 summary: Whilst a number of recent reports suggest that COVID-19 associated stroke tends to be severe, there is limited data on the effects of COVID-19 in prospective registries. One-way ANOVAs were performed to see significant mean level differences for all continuous variables according to Pre-COVID-19 ischemic stroke, COVID-19 Negative ischemic stroke and COVID-19 positive categories. keywords: admissions; covid-19; ischemic; pandemic; patients; stroke cache: cord-326626-ixxk6plf.txt plain text: cord-326626-ixxk6plf.txt item: #42 of 50 id: cord-327511-e3idvknz author: Trifan, G. title: Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome by Sex date: 2020-09-11 words: 3486 flesch: 49 summary: The effect of sex on stroke patients with SARS-CoV-2 infection has not been investigated. In our cohort, we observed that the presentation of stroke patients with SARS-CoV-2 was more pleomorphic with almost 40% of our cases having mild to moderate symptoms of COVID-19 or being asymptomatic at presentation. keywords: cov-2; covid-19; females; males; patients; sars; stroke; study cache: cord-327511-e3idvknz.txt plain text: cord-327511-e3idvknz.txt item: #43 of 50 id: cord-330137-7w7wqy4h author: Borhani-Haghighi, Afshin title: Time Is Brain: A Call to Action to Support Stroke Centers in Low- and Middle-Income Countries during the COVID-19 Pandemic date: 2020-07-15 words: 702 flesch: 42 summary: Stroke centers need to practice 24/7 outpatient support using secured video-audio applications or at least telephone questionnaires to address vascular risk factors and assure medication compliance. Finally, stroke centers in the world need to support each other. keywords: covid-19; lmics; stroke cache: cord-330137-7w7wqy4h.txt plain text: cord-330137-7w7wqy4h.txt item: #44 of 50 id: cord-332065-afq26621 author: Ghanchi, Hammad title: Racial Disparity Amongst Stroke Patients During the Coronavirus Disease 2019 Pandemic date: 2020-09-10 words: 2861 flesch: 39 summary: Ethnic disparities in stroke: the scope of the problem Divergent poststroke outcomes for black patients: Lower mortality, but greater disability Racial-ethnic disparities in stroke care: the American experience: a statement for healthcare professionals from the American Heart Association/American Stroke Association Effects of the COVID-19 pandemic on stroke patients. Given the recent pandemic and racial disparity among patients afflicted with SARS-CoV-2 and the possible link of this virus and cerebrovascular accidents (CVA), we sought to analyze whether there was a disparity for stroke patients presenting to hospitals during this time using the Get with the Guidelines (GWTG) National Stroke Database. keywords: covid-19; hospitals; patients; population; sars; stroke cache: cord-332065-afq26621.txt plain text: cord-332065-afq26621.txt item: #45 of 50 id: cord-334482-fpxd0ont author: Fifi, Johanna T title: COVID-19 related stroke in young individuals date: 2020-08-18 words: 1324 flesch: 45 summary: The neurological impact of COVID19 Largevessel stroke as a presenting feature of COVID19 in the young COVID19 is an independent risk factor for acute ischemic stroke Stroke and mechanical thrombectomy in patients with COVID19: technical observations and patient characteristics Treatment of acute ischemic stroke due to large vessel occlusion with COVID19: experience from Paris Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019 Emergent large vessel occlusion stroke during New York City's COVID19 outbreak: clinical characteristics and paraclinical findings Macrothrombosis and stroke in patients with mild Covid19 infection Intraluminal carotid artery thrombus in COVID19: another danger of cytokine storm? Outcomes and spectrum of major neurovascular events among COVID19 patients: a 3center experience 4, 5 Multiple regions with high COVID19 prevalence have reported stable or increased incidence of large vessel stroke and increased incidence of cryptogenic stroke (patients with no found typical cause of stroke), despite observing a decrease in mild See Rapid Review page 767 stroke that is possibly secondary to quarantine and selfisolation. keywords: covid19; patients; stroke; years cache: cord-334482-fpxd0ont.txt plain text: cord-334482-fpxd0ont.txt item: #46 of 50 id: cord-338628-7l9b5mqp author: Nguyen-Huynh, Mai N. title: Acute Stroke Presentation, Care, and Outcomes in Community Hospitals in Northern California During the COVID-19 Pandemic date: 2020-08-17 words: 3266 flesch: 55 summary: Because of the retrospective nature of the study, we did not have direct data on stroke patients who were not presenting to the ED. There was no increase in inpatient mortality for stroke patients who were admitted and treated during the pandemic. keywords: alert; covid-19; pandemic; patients; post; pre; sip; stroke cache: cord-338628-7l9b5mqp.txt plain text: cord-338628-7l9b5mqp.txt item: #47 of 50 id: cord-345437-j3akzx10 author: Perry, Richard title: What has caused the fall in stroke admissions during the COVID-19 pandemic? date: 2020-06-29 words: 694 flesch: 57 summary: Either the incidence of stroke has declined during this period, or a higher proportion of patients who have strokes are never reaching stroke services We reasoned that any change in the spectrum of stroke severity in patients presenting during the pandemic might yield important clues to distinguish between these two possibilities, as follows. keywords: patients; stroke cache: cord-345437-j3akzx10.txt plain text: cord-345437-j3akzx10.txt item: #48 of 50 id: cord-353824-0oyvia6d author: Farooque, Umar title: Coronavirus Disease 2019-Related Acute Ischemic Stroke: A Case Report date: 2020-09-08 words: 1880 flesch: 48 summary: The possibility as to whether anticoagulant or antiplatelet agents may be superior in stroke patients with COVID-19 requires further consideration. Negative pressure carrier isolators can be used to isolate COVID-19 patients during neurovascular imaging. keywords: acute; covid-19; infection; patients; risk; stroke cache: cord-353824-0oyvia6d.txt plain text: cord-353824-0oyvia6d.txt item: #49 of 50 id: cord-354866-5yzalrri author: Esenwa, Charles title: The effect of COVID-19 on stroke hospitalizations in New York City date: 2020-07-13 words: 1534 flesch: 49 summary: During the pandemic period, the slope was -4.4 (se = 1.00); i.e., the number of stroke admissions decreased an average of 4.4 per week, (p = 0.005), with weekly admissions averaging 23, a reduction of 44% versus baseline. We summarize acute stroke cases by age, sex, race/ethnicity. keywords: acute; admissions; covid-19; stroke cache: cord-354866-5yzalrri.txt plain text: cord-354866-5yzalrri.txt item: #50 of 50 id: cord-355481-1avavlu3 author: Anoop, Kohli title: “Changes in Stroke Presentation in Neo-Covid Patients: A Case Study” date: 2020-10-02 words: 1531 flesch: 46 summary: This case is perhaps the first one that shows clear multiple thromboembolic stroke phenomenon, facial pigmentation, adding a new variant to neo COVID strokes. A case of multiple embolic strokes, involving bilateral cerebral hemispheres is presented. keywords: changes; covid-19; figure; stroke cache: cord-355481-1avavlu3.txt plain text: cord-355481-1avavlu3.txt