item: #1 of 449 id: cord-000083-3p81yr4n author: None title: Poster Exhibition date: 2009-01-31 words: 113010 flesch: 51 summary: From this group of HBV patients 35 (98%) have had elevated urinal Dol excreation (45,8±5,2 g/ml vs . 3% and 47.4 respectively in HCC patients, 60.3% and 39.7 in LC patients, 55% and 40 in CHB patients, 55% and 40 in ACLF patients. keywords: activity; acute; adefovir; adv; afp; age; aim; aims; alt; alt levels; analysis; anti; assay; associated; b virus; background; baseline; blood; cancer; carcinoma; cases; cells; chb patients; china; chronic hcv; chronic hepatitis; clinical; combination; conclusion; control; control group; copies; correlation; data; days; development; diagnosis; difference; dna levels; dose; drug; effect; efficacy; end; etv; expression; factors; fibrosis; follow; gene; genotype; group; group b; hbeag; hbv dna; hbv genotype; hbv infection; hcc cell; hcc patients; hcv; hepatic; hepatitis b; hepatitis patients; hepatocellular; hospital; ifn; increase; infected; lamivudine; levels; liver; liver biopsy; liver cirrhosis; liver disease; load; low; male; markers; mean; median; medical; methods; model; months; mrna; mutation; nafld; negative; non; p<0.05; patients; patients chronic; pcr; positive; prevalence; protein; rate; ratio; rats; recurrence; related; resistance; respectively; response; results; rfa; risk; rna; role; samples; score; seroconversion; serum alt; serum hbv; significant; specific; study; study group; subjects; survival; svr; therapy; time; total; treatment; treatment group; tumor; university; virus; weeks; years cache: cord-000083-3p81yr4n.txt plain text: cord-000083-3p81yr4n.txt item: #2 of 449 id: cord-000285-7p3b6tyf author: HARTERT, Tina V. title: The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases date: 2010-04-08 words: 3853 flesch: 29 summary: The TCRI is a prospective cohort of mother-infant dyads enrolled in a longitudinal investigation of the relationship of infant viral respiratory infection severity and aetiology and the interaction of other risk factors on the development of childhood asthma and allergic diseases. The primary goals of the study are: (i) to investigate both the acute and the long-term health consequences of varying severity and aetiology of clinically significant viral respiratory tract infections on the outcomes of allergic rhinitis (AR) and early childhood asthma; and (ii) to identify the potentially modifiable factors that define children who are at greatest risk of developing asthma following infant respiratory viral infection. keywords: asthma; atopic; childhood; children; cohort; development; infant; infection; severity; study cache: cord-000285-7p3b6tyf.txt plain text: cord-000285-7p3b6tyf.txt item: #3 of 449 id: cord-000718-7whai7nr author: None title: ESP Abstracts 2012 date: 2012-08-22 words: 166798 flesch: 44 summary: Of those, 11 were also positive for tumor cells on cytological smears. At the papillary thyroid cancer progression matrix metalloprotease and specific tissue inhibitors of metalloprotease (TIMP-2) increased in the cytoplasm of tumor cells, but the concentration of TIMP-1 decreased. keywords: activity; acute; adenocarcinoma; age; aim; alk; amplification; analysis; antibodies; antibody; areas; associated; association; benign; biopsies; biopsy; bladder; blood; bone; braf; breast; breast cancer; breast carcinoma; cadherin; cancer; cancer cases; cancer cell; cancer patients; carcinoma; carcinoma cases; cases; cell carcinoma; cell lung; cell lymphoma; changes; chemotherapy; chronic; clinical; colon; colorectal; conclusion; control; correlation; cystic; cytoplasmic; data; dept; detection; development; diagnosis; diameter; differentiation; diffuse; disease; dna; egfr; epithelial; evaluation; examination; expression; expression levels; factor; features; female; fibrosis; findings; fish; follow; gastric; gene; gene expression; grade; group; growth; her2; high; histological; history; hospital; human; ihc; immunohistochemistry; index; infiltration; inflammation; inflammatory; invasion; invasive; involvement; ki67; kidney; left; lesions; levels; like; literature; liver; loss; lung; lung cancer; lymph; lymphoma; male; malignant; markers; mass; material; mean; median; medical; melanoma; metastases; metastatic; method; molecular; months; morphology; mutation; necrosis; negative; neoplasm; neoplastic; new; node; non; normal; nuclear; nuclei; number; objective; outcome; overexpression; p53; paraffin; parameters; pathology; patients; pattern; pcr; positive; positivity; potential; presence; present; primary; prognostic; progression; proliferation; prostate; protein expression; pulmonary; range; receptor; recurrence; renal; report; resection; respectively; response; results; right; risk; role; samples; sarcoma; score; sections; series; serum; significance; situ; size; skin; specific; specimens; spindle; stage; staining; status; stromal; studies; study; surgery; survival; system; therapy; thyroid; time; tissue; total; treatment; tumor cells; tumor grade; tumor size; tumor tissue; tumors; tumour; turkey objective; type; university; value; vascular; vimentin; women; years cache: cord-000718-7whai7nr.txt plain text: cord-000718-7whai7nr.txt item: #4 of 449 id: cord-000955-giw4z3ei author: Jackson, Stewart title: Risk factors for severe acute lower respiratory infections in children – a systematic review and meta-analysis date: 2013-04-17 words: 5415 flesch: 44 summary: We extracted all relevant information from each retained study (Supplementary Table S2 ) and assessed the quality of included studies using a modified GRADE scoring system (Supplementary Table S1 ) (8) . The following risk factors where associated with severe ALRI in a majority of included studies: Passive smoking. keywords: analysis; association; estimate; meta; odds; ratio; studies cache: cord-000955-giw4z3ei.txt plain text: cord-000955-giw4z3ei.txt item: #5 of 449 id: cord-000977-ka4261wc author: None title: ECR 2013 Book of Abstracts - B - Scientific Sessions date: 2013-03-07 words: 133260 flesch: 46 summary: Attenuation of anode heel effect with an aluminum filter and their influence on patient dose in lumbar spine radiography J. Soares, R. Dores, P. Sousa, S.I. Rodrigues, L.P.V. Ribeiro, A.F.C.L. Abrantes, R.P.P. Almeida; The aim of this study is to functionally map VWFA at the individual subject level using frequent words of the Portuguese lexicon, to develop a paradigm potentially useful for clinical patients. keywords: accuracy; acquisition; adc; agreement; aim; algorithm; analysis; angiography; arterial; arteries; artery; assessment; associated; attenuation; average; baseline; benign; blood; body; bone; brain; breast; cad; cancer; cancer patients; cardiac; cases; changes; comparison; conclusion; contrast; control; coronary; correlation; ct images; data; density; detection; diagnostic; diameter; differences; diffusion; digital; disease; dose; dose ct; dwi; enhancement; evaluation; examinations; exposure; fat; fbp; fdg; findings; flow; follow; function; good; group; high; image; image quality; imaging; increase; injection; length; lesions; levels; linear; liver; low; lung; mammography; materials; mdct; mean; measurements; methods; model; months; mri; negative; nodules; noise; non; normal; number; parameters; patients; performance; perfusion; pet; phantom; phase; point; post; potential; pre; procedure; protocol; pulmonary; purpose; quality; radiation; radiographers; radiologists; range; rate; ratio; ray; readers; reconstruction; reduction; reference; renal; resolution; response; results; risk; scale; scans; score; screening; sensitivity; sequences; signal; size; slice; snr; software; specificity; standard; studies; study; subjects; surgery; system; t mri; technique; test; therapy; time; tissue; total; treatment; tumour; ultrasound; underwent; use; values; vessel; volume; weighted; women; years cache: cord-000977-ka4261wc.txt plain text: cord-000977-ka4261wc.txt item: #6 of 449 id: cord-001221-due9tloa author: None title: ECR 2014, Part A date: 2014-02-27 words: 107894 flesch: 38 summary: On CT imaging, thermal ablation areas are well circumscribed and oval shaped. MR imaging allows earlier detection of residual liver tumour than CT imaging. keywords: ablation; acute; analysis; approach; assessment; benign; biopsy; body; bone; brain; brain imaging; breast imaging; cancer; cardiac; care; cases; changes; children; complex; complications; conditions; contrast; coronary; criteria; ct imaging; current; data; detection; development; diagnosis; differential; diffusion; disease; dose; e.g.; enhancement; evaluation; evidence; examination; fat; features; follow; functional; help; high; image; imaging; imaging biomarkers; imaging criteria; imaging features; imaging findings; imaging methods; imaging modalities; imaging techniques; importance; inflammatory; information; interventional; key; knowledge; learning; lecture; lesions; liver; lung; malignant; management; modality; mr imaging; mri; need; new; non; number; objectives; patients; perfusion imaging; pet; pitfalls; post; potential; practice; presentation; procedures; protocols; pulmonary; quality; radiation; radiologists; radiology; research; resonance imaging; response; results; risk; role; session; size; specific; staging; standard; stroke; studies; study; surgery; systems; therapy; time; tissue; treatment; tumour; tumour imaging; ultrasound; use; value; vascular; years cache: cord-001221-due9tloa.txt plain text: cord-001221-due9tloa.txt item: #7 of 449 id: cord-001835-0s7ok4uw author: None title: Abstracts of the 29th Annual Symposium of The Protein Society date: 2015-10-01 words: 138771 flesch: 38 summary: In conclusion, the analysis of hydropathic environments strongly suggests that the orientation of a residue in a three-dimensional structure is a direct consequence of its hydropathic environment, which leads us to propose a new paradigm, interaction homology, as a key factor in protein structure. In computer simulation modeling of protein structure in a solvent medium, explicit, implicit, effectivemedium, approaches are often adopted to incorporate the effects of solvation. keywords: acid; activation; activity; addition; affinity; amino; amyloid; analysis; antibodies; antibody; antigen; approach; assay; assembly; associated; bacterial; binding; biology; bonds; cancer; catalytic; cell; cellular; chain; changes; characterization; chemical; chemistry; coli; complex; computational; concentration; conditions; conformation; conserved; control; core; cross; crystal; crystal structure; data; department; determine; development; dimer; disease; disordered; disordered proteins; dna; docking; domain; drug; effect; energy; enzyme; essential; experiments; expression; factors; family; fluorescence; fluorescent protein; formation; forms; fragments; free; functions; gene; group; helix; human; hydrogen; hydrophobic; important; increase; inhibitors; institute; key; kinetic; level; ligand; light; like; lipid; loop; low; major; mass; mechanism; membrane protein; method; model; modification; molecular; molecules; motif; mutant; mutations; n protein; native; nature; new; nmr; non; novel; number; oligomers; order; pathways; peptide; potential; prediction; presence; present; process; processes; properties; protease; protein; protein aggregation; protein association; protein complexes; protein concentration; protein data; protein degradation; protein design; protein domain; protein dynamics; protein engineering; protein evolution; protein expression; protein families; protein folding; protein function; protein interactions; protein interface; protein kinases; protein molecules; protein production; protein sequences; protein stability; protein structure; protein surface; protein tyrosine; provide; range; ray; reaction; receptor; recognition; recombinant; region; regulation; research; residues; response; results; rna; role; self; sequence; set; shows; signal; signaling; simulations; site; size; solution; species; specific; specificity; spectroscopy; stability; state; step; structural; studies; study; substrate; subunit; surface; synthetic; system; target; target protein; tau protein; techniques; temperature; terminal; time; transcription; transfer; transition; transmembrane; type protein; understanding; unfolding; university; use; variants; virus; vitro; wild; work; yeast cache: cord-001835-0s7ok4uw.txt plain text: cord-001835-0s7ok4uw.txt item: #8 of 449 id: cord-001989-6gi3o5mu author: Faber, Timor title: Meta-analyses including non-randomized studies of therapeutic interventions: a methodological review date: 2016-03-22 words: 8230 flesch: 10 summary: A systematic review and meta-analysis Surgical cytoreduction for recurrent epithelial ovarian cancer The association between dietary patterns and type 2 diabetes: a systematic review and meta-analysis of cohort studies Risk of bleeding on triple antithrombotic therapy after percutaneous coronary intervention/ stenting: a systematic review and meta-analysis A meta-analysis of outcomes of endovascular abdominal aortic aneurysm repair in patients with hostile and friendly neck anatomy Surgical treatment and survival in patients with liver metastases from neuroendocrine tumors: a meta-analysis of observational studies Segmentectomy or lobectomy for early stage lung cancer: a meta-analysis Systematic review and meta-analysis of laparoscopic versus open colectomy with end ileostomy for non-toxic colitis Risk of cardiovascular disease from antiretroviral therapy for HIV: a systematic review Reduced esophageal cancer incidence in statin users, particularly with cyclo-oxygenase inhibition One versus double burr holes for treating chronic subdural hematoma meta-analysis A meta-analysis of reverse breech extraction to deliver a deeply impacted head during cesarean delivery Preoperative use of anti-TNF therapy and postoperative complications in inflammatory bowel diseases: a meta-analysis Meta-analysis of antibiotics and the risk of community-associated Clostridium difficile infection Laparoscopic right colectomy: a systematic review and meta-analysis of observational studies comparing two types of anastomosis Infliximab versus cyclosporine as rescue therapy in acute severe steroid-refractory ulcerative colitis: a systematic review and meta-analysis The Role of Thiopurines in Reducing the Need for Surgical Resection in Crohn's Disease: A Systematic Review and Meta-Analysis The effect of anesthetic technique on survival in human cancers: a meta-analysis of retrospective and prospective studies Outcome of Cervicocranial Artery Dissection with Different Treatments: A Systematic Review and Metaanalysis Sulbactam-based therapy for Acinetobacter baumannii infection: a systematic review and meta-analysis Cytoreductive surgery and HIPEC for peritoneal metastases combined with curative treatment of colorectal liver metastases: Systematic review of all literature and meta-analysis of observational studies Cabergoline use and risk of fibrosis and insufficiency of cardiac valves : Meta-analysis of observational studies Vitamin D treatment and mortality in chronic kidney disease: a systematic review and meta-analysis The effect of anti-tumor necrosis factor alpha agents on postoperative anastomotic complications in Crohn's disease: a systematic review Association of sulphonylurea treatment with all-cause and cardiovascular mortality: a systematic review and meta-analysis of observational studies Comparison of clinical outcome between simultaneous-bilateral and staged-bilateral total knee arthroplasty: a systematic review of retrospective studies Meta-analysis: colonoscopic post-polypectomy bleeding in patients on continued clopidogrel therapy Bisphosphonates and risk of subtrochanteric, femoral shaft, and atypical femur fracture: a systematic review and meta-analysis Use of thiopurines and risk of colorectal neoplasia in patients with inflammatory bowel diseases: a meta-analysis Antivenom therapy of carpet viper (Echis ocellatus) envenoming: effectiveness and strategies for delivery in West Africa Laparoscopic total gastrectomy versus open total gastrectomy for cancer: a systematic review and meta-analysis Systematic review and meta-analysis of robotic surgery compared with conventional laparoscopic and open resections for gastric carcinoma Effectiveness of Haemophilus influenzae type b vaccines administered according to various schedules: systematic review and meta-analysis of observational data Safety and efficacy of early pharmacological thromboprophylaxis in traumatic brain injury: systematic review and meta-analysis Urgent surgery compared with fibrinolytic therapy for the treatment of left-sided prosthetic heart valve thrombosis: a systematic review and meta-analysis of observational studies A meta-analysis of epidemiologic studies Fertility treatment and childhood cancer risk: a systematic meta-analysis Oral contraceptive pills as primary prevention for ovarian cancer: a systematic review and meta-analysis Use of insulin and insulin analogs and risk of cancer -systematic review and meta-analysis of observational studies Use of bisphosphonates and the risk of osteonecrosis among cancer patients: a systemic review and meta-analysis of the observational studies Risk of osteonecrosis in patients taking bisphosphonates for prevention of osteoporosis: a systematic review and meta-analysis Immunogenicity of monoclonal antibodies against tumor necrosis factor used in chronic immune-mediated Inflammatory conditions: systematic review and meta-analysis Effects of asthma severity, exacerbations and oral corticosteroids on perinatal outcomes Consumption of omega-3 fatty acids and the risk of skin cancers: A systematic review and meta-analysis Statins use and risk of depression: A systematic review and meta-analysis Statins and primary liver cancer: a meta-analysis of observational studies Reproductive and exogenous hormone factors in relation to risk of meningioma in women: a meta-analysis Oral contraceptive use and uterine leiomyoma risk: a meta-analysis based on cohort and case-control studies Clinical risk factors of delayed gastric emptying in patients after pancreaticoduodenectomy: a systematic review and meta-analysis Relationship between use of antidepressants and risk of fractures: a meta-analysis Rheumatoid factor and response to TNF antagonists in rheumatoid arthritis: Systematic review and meta-analysis of observational studies Statin use and the risk of biochemical recurrence of prostate cancer after definitive local therapy: a meta-analysis of eight cohort studies The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta-analysis Preoperative statin therapy is associated with lower requirement of renal replacement therapy in patients undergoing cardiac surgery: a meta-analysis of observational studies Statins are associated with reduced risk of gastric cancer: a systematic review and meta-analysis Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with Barrett's oesophagus: a systematic review and meta-analysis Statins are associated with reduced risk of esophageal cancer, particularly in patients with Barrett's esophagus: a systematic review and meta-analysis Statins are associated with a reduced risk of hepatocellular cancer: a systematic review and meta-analysis Association of statin use with risk of dementia: a meta-analysis of prospective cohort studies Insulin therapy and risk of colorectal cancer: an updated meta-analysis of epidemiological studies Bisphosphonate treatment and risk of esophageal cancer: a meta-analysis of observational studies The association between histamine 2 receptor antagonist use and Clostridium difficile infection: a systematic review and meta-analysis beta-adrenergic receptor antagonists and fracture risk: a meta-analysis of selectivity, gender, and site-specific effects Does early life exposure to antibiotics increase the risk of eczema? keywords: analysis; bias; cancer; disease; meta; nrsi; patients; reporting; results; review; risk; studies; study; therapy; treatment; use; versus cache: cord-001989-6gi3o5mu.txt plain text: cord-001989-6gi3o5mu.txt item: #9 of 449 id: cord-002705-ntokyoai author: Nasir, Nazrila Hairin title: Effectiveness of a fluid chart in outpatient management of suspected dengue fever: A pilot study date: 2017-10-04 words: 4467 flesch: 53 summary: Dengue: guidelines for diagnosis, treatment, prevention and control Dengue and dengue haemorrhagic fever Fact sheet No. 117 Cost of Dengue Cases in Eight Countries in the Americas and Asia: A Prospective Study Quality of life of dengue patients Fluid intake and decreased risk for hospitalization for dengue fever Comparison of the effects of oral hydration and intravenous fluid replacement in adult patients with non-shock dengue hemorrhagic fever in Taiwan Randomised primary health center based interventions to improve the diagnosis and treatment of undifferentiated fever and dengue in Vietnam Clinical and laboratory features that distinguish dengue from other febrile illnesses in endemic populations Use of simple laboratory features to distinguish the early stage of severe acute respiratory syndrome from dengue fever Early clinical and laboratory indicators of acute dengue illness Evaluating the effectiveness of a fluid chart to improve oral intake in suspected dengue fever patients: a feasibility study Early predictors of dengue infection in adults (EPOD)-A Malaysian outpatient experience Protocol for out-patient management of dengue illness in young adults Dengue Guidelines for Diagnosis, Treatment, Prevention and Control New Edition. The fluid chart is a simple, inexpensive tool that may reduce hospitalization and intravenous fluid requirement in suspected dengue patients. keywords: care; dengue; fluid; group; intervention; patients; study cache: cord-002705-ntokyoai.txt plain text: cord-002705-ntokyoai.txt item: #10 of 449 id: cord-002774-tpqsjjet author: None title: Section II: Poster Sessions date: 2017-12-01 words: 83566 flesch: 48 summary: The CHIP framework drives the complex inter-relationships between community-hospital engagement, reciprocal capacity-building, integration initiatives, and community-based research and evaluation, to create an interconnected network of health care services. Those living in urban centers should have the best ava1l~b1hty, chmce, and access to a variety of health care services because of the distribution of health care services, fac1lmes, and health professionals in concentrated in urban centers. keywords: access; address; age; aids; analysis; approach; areas; barriers; canada; cancer; care services; care system; case; child health; children; cities; city; clients; clinic; communities; community health; community services; conclusion; conditions; current; data; demographic; depression; development; disease; drug; education; effects; environmental; ethnic; experience; factors; family; findings; focus; food; government; group; health care; health centre; health education; health information; health insurance; health issues; health needs; health outcomes; health policy; health problems; health promotion; health research; health services; health status; health survey; health system; healthcare; help; hiv; homeless; hospital; housing; immigrants; impact; income; individuals; information; interventions; interviews; introduction; issues; key; knowledge; lack; level; life; living; low; medical; methods; model; mortality; national; neighborhood; new; non; number; paper; participants; patients; people; physical; poor; population; population health; poster; poverty; prevalence; prevention; primary; process; program; project; provide; providers; public; quality; rates; relationship; research; residents; resources; results; risk; role; sample; self; sessions; sexual; social; strategies; street; street health; studies; study; substance; support; survey; system; time; toronto; treatment; urban; use; users; women; work; workers; years; youth cache: cord-002774-tpqsjjet.txt plain text: cord-002774-tpqsjjet.txt item: #11 of 449 id: cord-003062-qm8kalyt author: Chowdhury, Fazle Rabbi title: The association between temperature, rainfall and humidity with common climate-sensitive infectious diseases in Bangladesh date: 2018-06-21 words: 4998 flesch: 48 summary: A previous study in Chittagong, Bangladesh showed increased malaria cases with increasing temperature Table 4 . Unfortunately, very few studies on the relationship between various environmental variables and trends of infectious disease incidence have been performed so far in Bangladesh, although there are reports of some infections increasing sporadically in different regions of the country keywords: bangladesh; cases; change; climate; diseases; encephalitis; malaria; pneumonia; study; temperature cache: cord-003062-qm8kalyt.txt plain text: cord-003062-qm8kalyt.txt item: #12 of 449 id: cord-003364-hp8psl4s author: Chen, Xiantao title: Lipid Transporter Activity-Related Genetic Polymorphisms Are Associated With Steroid-Induced Osteonecrosis of the Femoral Head: An Updated Meta-Analysis Based on the GRADE Guidelines date: 2018-12-03 words: 3765 flesch: 43 summary: A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group Genetic risk factors for glucocorticoid-induced osteonecrosis: a meta-analysis Correlation between steroid-induced osteonecrosis of the femoral head and hepatic CYP3A activity: a systematic review and meta-analysis GRADE: an emerging consensus on rating quality of evidence and strength of recommendations Incidence of genetic polymorphisms involved in lipid metabolism among Chinese patients with osteonecrosis of the femoral head Genetic susceptibility of corticosteroid-induced osteonecrosis of femoral head ApoB C7623T polymorphism predicts risk for steroid-induced osteonecrosis of the femoral head after renal transplantation Low molecular weight phenotype of Apo(a) is a risk factor of corticosteroid-induced osteonecrosis of the femoral head after renal transplant Vascular anatomy and microcirculation of skeletal zones vulnerable to osteonecrosis: vascularization of the femoral head Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head Association between polymorphisms of steroid induced osteonecrosis of the femoral head and traditional Chinese medicine syndrome types ABCB1 gene polymorphisms and glucocorticoid-induced avascular necrosis of the femoral head susceptibility: a meta-analysis Associations of polymorphisms of rs693 and rs1042031 in apolipoprotein B gene with risk of breast cancer in Chinese The role of autophagy in steroid necrosis of the femoral head: a comprehensive research review Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Influence of BCL2L11 polymorphism on osteonecrosis during treatment of childhood acute lymphoblastic leukemia Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia LDL-cholesterol concentrations: a genome-wide association study Incidence of osteonecrosis associated with corticosteroid therapy among different underlying diseases: prospective MRI study Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses Genetic association of a polymorphism of the cAMPresponsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation Roles of TNF-alpha gene polymorphisms in the occurrence and progress of SARS-Cov infection: a case-control study Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population Relationship between gene polymorphisms and syndrome types in steroid-induced femoral head osteonecrosis Relationship between gene polymorphisms and hereditary susceptibility of steroid-induced femoral head osteonecrosis in Linyi City of Shandong Province The correlation between apolipoprotein gene polymorphisms and steroid-induced osteonecrosis of the femoral head MDR1 gene polymorphisms are associated with glucocorticoid-induced avascular necrosis of the femoral head in a Chinese population Correlation between ABCB1C3435T and G2677T/A polymorphism and steroid-induced osteonecrosis of femoral head:a meta-analysis MDR1(ABCB1) gene polymorphisms associated with steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus The efficacy of statins in preventing glucocorticoid-related osteonecrosis in animal models: a meta-analysis Effectiveness of various hip preservation treatments for non-traumatic osteonecrosis of the femoral head: a network meta-analysis of randomized controlled trials Relationship between apolipoprotein B gene polymorphism and tendon-vessel stagnation syndrome of steroid induced osteonecrosis of the femoral head WebGestalt: an integrated system for exploring gene sets in various biological contexts Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population Genetic polymorphisms in plasminogen activator inhibitor-1 predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese population Polymorphisms in the glucocorticoid receptor gene and associations with glucocorticoidinduced avascular osteonecrosis of the femoral head Association of ABCB1/MDR1 polymorphisms in patients with glucocorticoid-induced osteonecrosis of the femoral head: evidence for a meta-analysis keywords: head; osteonecrosis; risk; sonfh; steroid; study cache: cord-003364-hp8psl4s.txt plain text: cord-003364-hp8psl4s.txt item: #13 of 449 id: cord-003532-lcgeingz author: None title: 39th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium, 19-22 March 2019 date: 2019-03-19 words: 80115 flesch: 48 summary: Blood cultures were sent as per clinical & laboratory diagnosis of sepsis in ICU patients. Conclusions: HR, lactate levels and age before AVP initiation can predict the response to AVP in ICU patients with NE-resistant hypotension. keywords: acute; admission; age; aim; aki; analysis; arrest; arterial; assessment; baseline; blood; cardiac; care; care unit; cases; clinical; complications; conclusions; correlation; critical; data; days; diagnosis; difference; discharge; ecmo; effect; emergency; factors; failure; fig; figure; fluid; group; high; hospital; hospital mortality; hours; icu; icu admission; icu patients; ill; incidence; increase; injury; intensive; intervention; introduction; lactate; length; levels; low; lung; management; map; mean; median; medical; methods; months; mortality; non; organ; outcome; patients; patients introduction; period; post; pressure; rate; ratio; response; results; resuscitation; risk; score; sepsis; sepsis patients; septic; serum; severity; shock patients; sofa; stay; studies; study; surgery; survival; system; table; test; therapy; time; total; trauma; treatment; ultrasound; unit; use; ventilation; years cache: cord-003532-lcgeingz.txt plain text: cord-003532-lcgeingz.txt item: #14 of 449 id: cord-004167-r2s0gks8 author: Cutts, Julia C. title: Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review date: 2020-01-16 words: 8607 flesch: 32 summary: We conducted a systematic review and meta-analysis of population-based studies (published up to 07 June 2019) of pregnant women living in P. falciparum endemic areas that examined antibody responses to pregnancy-specific P. falciparum antigens and outcomes including placental malaria, low birthweight, preterm birth, peripheral parasitaemia, maternal anaemia, and severe malaria. Included studies varied in terms of antigens tested, methodology used to measure antibody responses, and epidemiological setting. keywords: antibodies; antibody; antigens; estimates; falciparum; infection; malaria; placental; pregnancy; responses; studies; study; var2csa; women cache: cord-004167-r2s0gks8.txt plain text: cord-004167-r2s0gks8.txt item: #15 of 449 id: cord-004314-gtwtakpr author: Holmen, Heidi title: Working with patients suffering from chronic diseases can be a balancing act for health care professionals - a meta-synthesis of qualitative studies date: 2020-02-10 words: 8171 flesch: 43 summary: Together, these themes describe how clinical encounters with patients depend, to a large degree, on the personal interaction between patient and professional, real clinical practice situations and professional ideals, and contextual support and managing one's own emotions. key: cord-004314-gtwtakpr authors: Holmen, Heidi; Larsen, Marie Hamilton; Sallinen, Merja Helena; Thoresen, Lisbeth; Ahlsen, Birgitte; Andersen, Marit Helen; Borge, Christine Råheim; Eik, Hedda; Wahl, Astrid Klopstad; Mengshoel, Anne Marit title: Working with patients suffering from chronic diseases can be a balancing act for health care professionals - a meta-synthesis of qualitative studies date: 2020-02-10 journal: BMC Health Serv Res DOI: 10.1186/s12913-019-4826-2 sha: doc_id: 4314 cord_uid: gtwtakpr BACKGROUND: keywords: care; diabetes; disease; experiences; hcps; health; nurses; papers; patients; research; studies; study; working cache: cord-004314-gtwtakpr.txt plain text: cord-004314-gtwtakpr.txt item: #16 of 449 id: cord-004385-xna32qve author: Zhou, Yuqing title: Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis date: 2020-02-20 words: 4497 flesch: 36 summary: The small number of included studies and the small number of patients in the included studies might also make the effect size of some outcome indicators insufficient, and we were unable to analyse the effect of some factors on the outcome indicators by meta-regression or subgroup analysis. In a study of 2141 patients with severe influenza pneumonia 15 , 245 patients had nosocomial infection, and the most commonly isolated pathogens were Acinetobacter baumannii (35.0%), Pseudomonas aeruginosa (13.5%), and Staphylococcus aureus (11.0%), while in another cohort study of 1846 patients with severe influenza pneumonia 8 , Streptococcus pneumoniae (49.1%), Pseudomonas aeruginosa (10.1%), and Staphylococcus aureus (7.5%) were the most frequently isolated microorganisms. keywords: analysis; corticosteroid; influenza; mortality; patients; pneumonia; studies; study cache: cord-004385-xna32qve.txt plain text: cord-004385-xna32qve.txt item: #17 of 449 id: cord-004515-x22q1f21 author: Pottecher, Julien title: Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients date: 2020-03-18 words: 6820 flesch: 38 summary: The primary trial objective is to demonstrate a reduction in the incidence of moderate-to-severe hypoxaemia in severe trauma patients during the first 7 days from 45% to 30% by providing aerosolized dornase alfa as compared to placebo. This treatment may facilitate ventilator weaning, reduce the burden of trauma-induced lung inflammation and facilitate recovery and rehabilitation in severe trauma patients. keywords: alfa; analysis; blood; data; day; days; dna; dornase; hypoxaemia; incidence; injury; lung; patients; study; trauma; trial; variables cache: cord-004515-x22q1f21.txt plain text: cord-004515-x22q1f21.txt item: #18 of 449 id: cord-004534-jqm1hxps author: None title: Abstract date: 2009-06-09 words: 139178 flesch: 39 summary: This simple model illustrates how differential detergent selectivity for faces and strong constraints coming from purely environmental features could influence transmembrane helix packing, membrane protein structure and assembly. Imaging of mobile stable lipid rafts in the live cell plasma membrane M. Brameshuber 1 , J. Weghuber 1 , V. Ruprecht 1 , H. Stockinger 2 , G. J. Schuetz 1 1 Johannes Kepler University Linz, Austria, 2 Medical University of Vienna, Austria The organization of the cellular plasma membrane at a nanoscopic length scale is believed to affect the association of distinct sets of membrane proteins for the regulation of multiple signaling pathways. keywords: acid; actin; activation; activity; addition; affinity; afm; aggregates; aggregation; amyloid; analysis; applications; approach; assembly; atomic; atp; behavior; bilayer; binding; biological; biology; biophysics; brain; calcium; cancer; cell; cell membrane; cell surface; center; chain; changes; channel; characterization; charge; chemical; chemistry; cholesterol; combination; complex; complexes; concentration; conditions; confocal; conformational; constant; contrast; control; correlation; cross; current; data; decrease; delivery; density; department; design; detection; development; diffusion; disease; distribution; dna; domain; drug; dynamics; effect; electron; emission; energy; environment; enzyme; excitation; experiments; expression; fibrils; field; flow; fluorescence; fluorescence microscopy; fluorescent protein; force; force microscopy; formation; france; free; fret; function; gene; genova; germany; group; growth; helix; human; imaging; increase; influence; institute; intensity; interaction; intracellular; italy; key; kinetics; laser; length; level; lifetime; ligand; light; lipid; lipid membranes; liposomes; living; measurements; mechanism; membrane; membrane protein; membrane surface; method; microscopy; model; model membrane; molecular; molecules; muscle; mutant; nanoparticles; neuronal; neurons; new; non; novel; number; order; parameters; particles; peptide; phase; physical; physics; plasma membrane; pore; potential; presence; present; probe; process; processes; properties; protein; protein complexes; protein dynamics; protein interactions; protein structure; range; rate; ray; reaction; receptor; region; release; report; research; residues; resolution; response; results; rna; role; sample; scanning; scattering; sciences; second; self; sequence; signal; simulations; site; size; solvent; species; specific; spectroscopy; stability; state; step; structure; studies; study; surface; system; target; techniques; temperature; terminal; time; transfer; transition; transmembrane; transport; treatment; type; understanding; unfolding; university; use; vesicles; virus; vitro; vivo; water; work cache: cord-004534-jqm1hxps.txt plain text: cord-004534-jqm1hxps.txt item: #19 of 449 id: cord-004584-bcw90f5b author: None title: Abstracts: 8th EBSA European Biophysics Congress, August 23rd–27th 2011, Budapest, Hungary date: 2011-08-06 words: 106959 flesch: 38 summary: to that of cell proteins (amide II band at *1550 cm -1 ) Membrane proteins and peptides are acting in an environment rich in other proteins or peptides. keywords: acid; actin; activation; activity; affinity; aggregation; amino; amyloid; analysis; applications; approach; assembly; associated; atomic; bilayer; binding; biological; cancer; cell; cell membrane; cell surface; chain; changes; channel; charge; chemical; cholesterol; complex; complexes; composition; compounds; concentration; conditions; conformational; control; correlation; data; delivery; detection; development; diffusion; distribution; dna; domain; drug; dynamics; effect; electron; energy; environment; enzyme; experiments; expression; fast; field; fluorescence; force; formation; free; function; fusion; gene; group; human; hydrophobic; imaging; increase; influence; institute; interaction; key; kinetics; laser; level; ligand; light; lipid; lipid membranes; liposomes; living; magnetic; major; measurements; mechanism; membrane; membrane binding; membrane interaction; membrane protein; membrane structure; membrane surface; method; microscopy; model; model membrane; molecular; molecules; nanoparticles; native; network; new; nmr; non; novel; number; order; organization; parameters; peptide; phase; plasma membrane; potential; presence; processes; properties; protein; protein complex; protein dynamics; protein interactions; protein structure; proton; range; rate; ray; reaction; receptor; region; regulation; research; residues; resolution; response; results; role; scattering; self; signal; simulations; sites; size; species; specific; spectra; spectroscopy; stability; state; structure; studies; study; substrate; surface; system; techniques; temperature; terminal; time; transfer; transition; transport; type; understanding; university; use; vesicles; vitro; vivo; water; work cache: cord-004584-bcw90f5b.txt plain text: cord-004584-bcw90f5b.txt item: #20 of 449 id: cord-004636-t6qldq3s author: Saugel, Bernd title: Journal of Clinical Monitoring and Computing end of year summary 2019: hemodynamic monitoring and management date: 2020-03-14 words: 10310 flesch: 38 summary: An observational cohort study in cardiac surgery patients was performed by Henriques et al. The authors obtained arterial blood pressure measurements from aortic, femoral, and radial artery catheters. keywords: analysis; arterial; authors; blood; cardiac; data; et al; fluid; group; learning; monitoring; patients; pressure; pulse; study; surgery; time cache: cord-004636-t6qldq3s.txt plain text: cord-004636-t6qldq3s.txt item: #21 of 449 id: cord-004879-pgyzluwp author: None title: Programmed cell death date: 1994 words: 81833 flesch: 47 summary: 8cl-2(z is a mitochondrial or perinuclear-associated oncoprotein that prolongs the life span of a variety of cell types by interfering with programmed cell death. Single and repetitive uptake and release of CPZ were measured in each cell type after individual exposure or exposure in any combination of cell types: In 2 hour competitive uptake studies fibreblasts reached 1.7 and 2.6 times the concentrations of C6-and ROC-cells, :respectively. keywords: acid; activation; activity; addition; adult; amino; analysis; animals; antibodies; binding; brain; calcium; cdna; cell lines; cells; changes; cloned; complex; concentrations; conditions; contrast; control; cultures; current; data; days; decrease; development; different; differentiation; dna; domain; early; effects; end; enzyme; epithelial; experiments; expression; extracts; factor; family; fold; form; formation; function; fusion; gene; gene expression; growth; homology; hormone; human; increase; induction; infected; inhibition; institut; interaction; intracellular; kda; kinase; levels; major; mammalian; mechanisms; medium; membrane; mice; molecular; mouse; mrna; muscle; mutant; nerve; neuronal; neurons; new; non; nuclear; nucleus; number; order; pathway; phosphorylation; play; positive; potential; presence; present; process; production; promoter; properties; protein; protein expression; rat; rate; rats; reaction; receptor; recombinant; recombination; region; regulation; release; replication; response; results; rna; role; sequence; signal; sites; species; specific; stage; stimulation; structure; studies; study; subunit; surface; synthesis; system; t cells; target; terminal; time; tissue; tnf; transcription; treatment; tumor; type; university; virus; vitro; vivo; yeast cache: cord-004879-pgyzluwp.txt plain text: cord-004879-pgyzluwp.txt item: #22 of 449 id: cord-004894-75w35fkd author: None title: Abstract date: 2006-06-14 words: 92227 flesch: 48 summary: A marked interindividual variability in high risk patients is seen, but at present the basis for this variability is unclear and can not be explained solely by environmental factors. Conclusion and discussion: This study provides evidence for a role for genetic variation of MCP-1 gene in the occurrence of coronary collaterals in high risk patients. keywords: abstract; age; analysis; association; background; baseline; birth; blood; bmi; breast; breast cancer; cancer patients; cancer risk; cardiovascular; care; cases; characteristics; chd; children; clinical; cohort; cohort study; conclusion; control; coronary; countries; data; death; design; diabetes; differences; discussion; disease; dutch; effect; epidemiological; european; evidence; exposure; follow; general; group; health; incidence; increase; index; information; intake; levels; life; mean; methods; model; months; mortality; netherlands; non; number; objectives; outcome; participants; patients; period; population; practice; pressure; prevalence; primary; public; quality; questionnaire; rates; ratio; regression; research; results; risk; risk factors; risk patients; screening; self; smoking; specific; status; studies; study; subjects; survival; time; total; treatment; use; weight; women; years cache: cord-004894-75w35fkd.txt plain text: cord-004894-75w35fkd.txt item: #23 of 449 id: cord-004948-ad3i9wgj author: None title: 7th International Congress on Amino Acids and Proteins : Vienna, Austria, August 6–10, 2001 date: 2001 words: 73789 flesch: 41 summary: After the performic acid oxidation and the 6 M HCl hydrolysis of the protein, OPA/TATG (o-phthaldialdehyde/tetra-O-acetyl-1-thio--D-glucopiranoside) precolumn derivatisation method was used, and the enantiomers of sulphur containing amino acids were separated by RP-HPLC (LiChrosphere 100 RP-18e, 125 ϫ 4 mm, 5 µm column, Merck-Hitachi LaChrom HPLC). The dominant ones are water, ethanol, glycerol, sugars, organic acids, and various ions, while amino acids are present at much lower concentration. keywords: acids; activation; activities; activity; addition; administration; amino acid; analysis; animals; antagonists; apoptosis; approach; arginine; binding; biological; blood; brain; cancer; cell; chain; changes; clinical; complex; compounds; concentration; conditions; content; control; cysteine; data; decrease; department; derivatives; development; disease; dna; dopa; effect; enzyme; ethanol; experiments; expression; following; formation; free; function; gaba; gel; gene; glucose; glutamate; glutamine; group; growth; human; identification; increase; inhibition; institute; leucine; levels; liver; lysine; mass; mechanism; membrane; metabolism; methionine; method; mice; model; molecular; mrna; new; nmda; non; number; patients; peptide; plasma; polyamines; present; production; properties; proteins; rats; reaction; receptor; reduced; release; research; response; results; role; samples; sequence; stress; structure; studies; study; substrate; synthesis; system; taurine; time; tissue; transport; treatment; tumor; type; university; uptake; vitamin; vitro; vivo cache: cord-004948-ad3i9wgj.txt plain text: cord-004948-ad3i9wgj.txt item: #24 of 449 id: cord-005105-twsy61oq author: None title: SIU 2015 Abstracts date: 2015-09-21 words: 124278 flesch: 51 summary: Th e patients were discharged from hospital aft er a median of 4.5 days (range 3 to 7). Th e patients were classifi ed into Group 1 (n=67, 60.3%) and into Group 2 (n=44, 39.7%) based on the presence of BPH. keywords: aft; age; analysis; approach; average; biopsy; bladder; bladder cancer; blood; cancer; cancer patients; carcinoma; cases; catheter; cells; clinical; complications; conclusion; control; data; day; days; defi; diagnosis; diff; disease; dysfunction; e aim; e bladder; e diff; e fi; e incidence; e mean; e median; e patient; e results; e study; e use; ects; eff; effi; ere; erectile; erence; experience; expression; factors; female; follow; function; grade; group; group patients; hospital; identifi; improvement; index; initial; injury; introduction; kidney; laparoscopic; left; level; male; management; medical; months; nephrectomy; non; number; objective; operative; outcomes; overall; pain; patients; pca; pelvic; period; positive; post; postoperative; preoperative; primary; procedure; prostate; prostate cancer; prostatectomy; prostatic; psa; radical; range; rate; recurrence; renal; results; risk; rst; score; signifi; single; size; specifi; stage; standard; stent; stone; stricture; studies; study; surgery; surgical; survival; symptoms; technique; term; th e; therapy; time; total; tract; treated; treatment; tumor; urethral; urinary; urine; voiding; volume; weeks; years cache: cord-005105-twsy61oq.txt plain text: cord-005105-twsy61oq.txt item: #25 of 449 id: cord-005147-mvoq9vln author: None title: Autorenregister date: 2017-02-23 words: 86765 flesch: 41 summary: While a long list of gene mutations have so far been described to be responsible for the disease phenotype, little is known about the underlying neuronal mechanisms. WD pathogenesis, however, can not only be explained by gene coding mutations since phenotypes exhibit strong variations despite the same exonic DNA makeup in the gene. keywords: activity; addition; age; allele; analysis; approach; array; association; autosomal; blood; brain; breast; cancer; candidate; carriers; cases; cause; cell; children; chromosome; clones; coding; cohort; complex; conclusion; controls; data; delay; deletion; development; diagnosis; different; disability; disease; disease genes; disorders; dna; dominant; effect; exome; exome sequencing; exon; expression; factors; families; family; features; female; findings; function; gene; gene expression; generation; genetic; genome; genomic; germany; germline; growth; heterozygous; homozygous; human; identification; individuals; institute; levels; loci; loss; low; methods; methylation; mice; missense; model; molecular; mouse; mrna; mutations; negative; new; ngs; non; normal; novel; novo; number; onset; p =; panel; parents; pathways; patients; pcr; phenotype; potential; present; protein; receptor; recessive; regions; report; results; risk; rna; role; samples; sequence; sequencing; sites; skin; specific; spectrum; splice; splicing; studies; study; syndrome; system; target; testing; time; tissue; transcription; treatment; tumor; variants; wes; years cache: cord-005147-mvoq9vln.txt plain text: cord-005147-mvoq9vln.txt item: #26 of 449 id: cord-005497-w81ysjf9 author: None title: 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date: 2020-03-24 words: 103795 flesch: 50 summary: Conclusions: This is one of the first studies to demonstrate that abnormal RV function is associated with an increased mortality in ICU patients with pneumonia. The fast efficacy of targeted therapies led some intensivists to use them as rescue therapy for ICU patients. keywords: acute; administration; admission; adult patients; age; aim; aki; aki patients; analysis; approach; arrest; arterial; associated; association; average; baseline; blood; cardiac; care; care patients; care unit; cases; clinical; cohort; cohort study; complications; control; critical; critical care; data; day mortality; days; death; delirium; difference; discharge; disease; early; ecmo; effect; emergency; factors; failure; figure; fluid; function; group; hospital; hospital mortality; hours; icu admission; icu mortality; icu patients; icu stay; ill; incidence; increase; index; infection; injury; intensive; introduction; length; levels; low; lps; lung; management; mean; median; medical; methods; min; model; months; mortality; non; number; observational; organ; outcome; pain; parameters; patients; period; plasma; population; positive; post; pressure; rate; renal; results; risk; score; sepsis; sepsis patients; septic; serum; shock; shock patients; sofa; stay; studies; study; support; surgery; survival; table; test; therapy; time; total; treatment; unit; university; use; value; ventilation; volume; years cache: cord-005497-w81ysjf9.txt plain text: cord-005497-w81ysjf9.txt item: #27 of 449 id: cord-005569-9d51l6bn author: Antonelli, Massimo title: Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia date: 2008-12-09 words: 10277 flesch: 36 summary: Entropy of the frontal EEG does not discriminate sedation state adequately for clinical use in ICU patients. The cumulated energy deficit in ICU patients primarily on enteral nutrition, which has been reported in several studies, is mainly related to underfeeding during the initial week of ICU stay. keywords: acute; authors; care; control; delirium; glucose; icp; icu; infection; intensive; levels; monitoring; mortality; non; outcome; patients; sepsis; shock; study; therapy cache: cord-005569-9d51l6bn.txt plain text: cord-005569-9d51l6bn.txt item: #28 of 449 id: cord-005600-gsbbjb5y author: De Jonghe, B. title: Acquired neuromuscular disorders in critically ill patients: a systematic review date: 1998 words: 3832 flesch: 33 summary: The first two types of drugs have been been frequently associated with the occurrence of CINMA in ICU patients with acute asthma or ARDS. Early systematic detection of electrophysiologic abnormalities in ICU patients might have prognostic value, since these abnormalities are associated with a high mortality keywords: abnormalities; cinma; electrophysiologic; icu; muscle; patients; studies cache: cord-005600-gsbbjb5y.txt plain text: cord-005600-gsbbjb5y.txt item: #29 of 449 id: cord-005646-xhx9pzhj author: None title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date: 1996 words: 72090 flesch: 51 summary: Objective: To assess the normal ,gastric intramucosal pH ~Hi) by tonometry in healthy children Patients and methods: Twelve healthy children (6 males and 6 females) with age rmaged from 6 months to 12 years scheduled for minor plastic or urologic surgery. Pain relief was good (VRS less 2) in 53 children -94.6 % of study patients. keywords: acute; administration; admission; age; airway; analysis; ards; arterial; average; babies; blood; brain; cardiac; care; cases; changes; chest; children; complications; conclusion; cpb; criteria; data; days; death; diagnosis; difference; disease; dose; drug; duration; ecmo; effects; failure; flow; gas; group; heart; high; hospital; hours; hypertension; icu; ill; incidence; increase; infants; infusion; initial; injury; intensive; levels; life; lung; management; mean; measurements; mechanical; median; medical; methods; minutes; months; mortality; neonatal; neonates; newborns; nitric; non; nurses; outcome; oxide; oxygenation; parameters; patients; peak; pediatric; period; phi; picu; plasma; post; present; pressure; prism; pulmonary; range; rate; response; results; risk; score; sepsis; severe; severity; study; support; surgery; survivors; syndrome; system; test; therapy; time; total; treatment; unit; use; values; ventilation; volume; weeks; weight; years cache: cord-005646-xhx9pzhj.txt plain text: cord-005646-xhx9pzhj.txt item: #30 of 449 id: cord-005727-li8pwigg author: None title: ESICM 2010 MONDAY SESSIONS 11 October 2010 date: 2010-08-31 words: 102900 flesch: 50 summary: Postoperative sedation with both midazolam and dexmedetomidine were effective in suppressing oxidative stress in ICU patients. Poorly controlled pain in the postoperative period can lead to slow recovery and life threatening complications, especially in elderly patients. The use of a tidal volume of 6 ml/kg of predicted body weight is part of the management of patients presenting with ARDS (1) and prevents ventilator induced lung injury in ICU patients undergoing mechanical ventilation (2) . keywords: acute; admission; adult patients; age; aim; analysis; apache; arrest; arterial; assessment; blood; brain; cardiac; care; care patients; care unit; changes; complications; conclusions; control; critical; daily; data; days; diagnosis; differences; discharge; disease; early; effects; factors; failure; family; flow; fluid; following; glucose; group; hospital; hospital mortality; hypothermia; icu admission; icu mortality; icu patients; incidence; increased; infection; injury; intensive; introduction; invasive; length; levels; lung; management; mean; measurement; median; medical; methods; min; mmol; model; monitoring; mortality; n =; niv; non; number; nurses; objectives; organ; outcome; oxygen; p =; parameters; patients; pct; period; post; pressure; prospective; range; rate; results; risk; score; sedation; sepsis; septic; shock; staff; stay; studies; study; support; surgery; survival; system; temperature; test; therapy; time; total; treatment; unit; use; value; vap; variables; ventilation; volume; years cache: cord-005727-li8pwigg.txt plain text: cord-005727-li8pwigg.txt item: #31 of 449 id: cord-005750-54hul2lw author: Antonelli, Massimo title: Year in review in Intensive Care Medicine, 2008: III. Paediatrics, Ethics, outcome research and critical care organization, sedation, pharmacology and miscellanea date: 2009-02-10 words: 8237 flesch: 41 summary: Policies were not modified for child patients in 9% of ICUs, nor for a dying patient in 21%. [36] review a few recent randomized clinical trials performed on severely ill patients (the ARMA trial comparing a low and a lage Vt in ARDS, the trial assessing the effect of growth hormone in ICU patients and the TRICC trial, on the level of blood transfusion, also in ICU patients) and emphasise the crucial importance of the control group. keywords: acute; authors; cardiac; care; children; critical; end; et al; icu; intensive; life; mortality; paediatric; patients; risk; shock; study; use cache: cord-005750-54hul2lw.txt plain text: cord-005750-54hul2lw.txt item: #32 of 449 id: cord-005777-6rvfsx4p author: None title: PS 0420-0716 date: 2007-08-25 words: 59296 flesch: 50 summary: The aim of this study was to determine the risk factors and mortality rate of acinetobacter baumanii infections in ICU patients. It has been considered to play a role in worsening the prognosis of ICU patients. keywords: acute; admission; age; aim; analysis; apache; ards; ards patients; arterial; blood; cardiac; care; cases; complications; conclusion; control; data; days; dose; factors; failure; function; group; hospital; hours; icu; icu mortality; icu patients; incidence; increase; infection; infusion; injury; intensive; lactate; length; levels; liver; lung; mean; median; medical; mortality; non; outcome; parameters; patients; peep; period; pneumonia; pressure; pts; pulmonary; rate; ratio; results; risk; score; sepsis; septic; serum; shock; stay; study; surgery; test; therapy; time; total; tracheostomy; treatment; unit; use; values; ventilation; years cache: cord-005777-6rvfsx4p.txt plain text: cord-005777-6rvfsx4p.txt item: #33 of 449 id: cord-005814-ak5pq312 author: None title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 words: 179325 flesch: 51 summary: Leukemia inhibitory factor (LIF), a growth factor recently recognised as a polyfunctional cytokine integrated in cytokine networks was measured in unconcentrated BALF of patients from different patient groups. It is difficult to generalize on intensive care units as different patient groups are in different ICUs aud there are great changes from one hospital to another and from one country to another. keywords: activity; acute; administration; admission; adult patients; age; aim; airway; analysis; apache; application; ards patients; arf; arterial; artery; assess; average; baseline; blood; blood flow; blood pressure; blood volume; breathing; cardiac; care patients; care unit; cases; catheter; cerebral; changes; chest; children; clinical; compliance; complications; concentration; conclusions; conditions; constant; control group; control patients; copd patients; correlation; course; cpb; criteria; critical; cvp; daily; damage; data; days; death; death patients; decrease; diagnosis; difference; disease; dose; drugs; duration; dysfunction; effect; emergency; end; evaluation; exchange; factors; failure; failure patients; findings; flow; fluid; following; frequency; function; gas; gastric; general; good; group; group b; group ii; group patients; h20; head; heart; hemodynamic; hepatic; hospital; hours; hypertension; icp; icu patients; iii; ill; illness; improvement; incidence; increase; index; infection; influence; infusion; injury; intensive; introduction; intubation; lactate; left; levels; life; liver; lung; male; management; map; mean; measurements; median; medical; methods; min; minutes; mmhg; model; monitoring; mortality; mortality rate; muscle; myocardial; need; negative; new; non; normal; number; objectives; onset; operation; order; organ; outcome; output; oxygen; oxygenation; p =; p<0.05; pao2; parameters; patients; patients methods; pattern; peep; perfusion; period; phase; phi; plasma; population; position; postoperative; presence; present; pressure; pressure support; procedure; protocol; pts; pulmonary; rain; range; rate; rats; reduction; renal; resistance; respiratory; response; results; right; risk; risk patients; samples; saps; score; sepsis; septic; serum; severe; severity; shock; shock patients; signs; specific; standard; status; stay; studies; study; study group; study period; subjects; support; surgery patients; surgical; survival; survivors; syndrome; system; systemic; technique; temperature; test; therapeutic; therapy; time; tissue; total; tracheal; transplantation; trauma patients; treatment; tube; type; unit; university; use; values; variables; vascular; vein; venous; ventilation; ventricular; volume; weaning; years cache: cord-005814-ak5pq312.txt plain text: cord-005814-ak5pq312.txt item: #34 of 449 id: cord-005816-i54q5gsu author: None title: 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date: 2009-08-06 words: 83218 flesch: 50 summary: Liberal utilization of abdominal sonography and abdominal CT scan may reduce missed acute abdomen in abdominal pain patients and appropriate radiological imaging and meticulous evaluation of the X-rays may reduce unnoticed spinal, pelvic and facial fractures in trauma patients. The e-mail noticed us, the presenting author of this abstract (Akira Endo) posted 3 or more abstract as a presenting author, however, the authors of 'Increased mortality in trauma patients with systolic hypertension' believed that Akira Endo in Department of ACCDM, TMDU, Japan surely posted this abstract only. keywords: abdomen; abdominal; acute; admission; age; aim; appendicitis; approach; area; artery; average; bleeding; blood; blunt; bone; burn; burn patients; care; cases; cause; chest; colon; complications; conclusion; control; data; days; department; diagnosis; disease; emergency; evaluation; examination; factors; female; findings; fixation; follow; fractures; general; good; group; head; healing; hospital; infection; initial; injuries; injury; introduction; knee; laparotomy; left; liver; male; management; mean; medical; methods; months; morbidity; mortality; n =; number; operation; outcome; p =; pain; patients; penetrating; perforation; period; postoperative; present; procedure; range; rate; reduction; results; right; risk; score; second; severity; stay; study; surgery; system; technique; time; tissue; total; trauma patients; treatment; type; weeks; wound; years cache: cord-005816-i54q5gsu.txt plain text: cord-005816-i54q5gsu.txt item: #35 of 449 id: cord-005881-oswgjaxz author: None title: Abstracts: 11(th) European Congress of Trauma and Emergency Surgery May 15–18, 2010 Brussels, Belgium date: 2010 words: 72013 flesch: 48 summary: The aim of this study was therefore to establish the impact of anaemia and blood transfusion on postoperative recovery of hip fracture patients. We assessed the adherence of these guidelines on the initial pre-operative management of tetanus prone open orthopaedic injuries in trauma patients admitted for surgery. keywords: acute; age; aim; analysis; approach; average; bone; care; cases; complications; conclusion; control; data; days; difference; disclosure; emergency; evaluation; failure; fixation; follow; fracture patients; fractures; good; group; head; healing; hospital; incidence; infection; injuries; injury; introduction; knee; liver; long; management; material; mean; medical; methods; months; mortality; nail; non; number; operation; operative; osteosynthesis; outcome; pain; patients; period; plate; postoperative; procedure; range; rate; reduction; relationships; repair; results; risk; score; screw; standard; stiffness; studies; study; surgery; system; technique; tibial; time; tissue; total; training; trauma patients; treatment; type; use; weeks; wound; years cache: cord-005881-oswgjaxz.txt plain text: cord-005881-oswgjaxz.txt item: #36 of 449 id: cord-006182-kck5e1ry author: None title: 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date: 2019-10-01 words: 87787 flesch: 45 summary: Whether a laboratory response in coagulation dosing, laboratory response, hemostatic efficacy and patient outcomes. A project aimed at improving DI management through predictive assessments and DDAVP protocols could potentially improve patient outcomes. keywords: acute; admission; adult patients; analysis; arrest; arrest patients; asah; associated; association; baseline; blood; brain; brain injury; cardiac; care; case; center; cerebral; changes; cohort; common; complications; data; days; dci; death; diagnosis; difference; discharge; disease; dose; edema; eeg; factors; functional; gcs; group; hemorrhage; higher; hospital; hours; ich patients; icp; icu; imaging; improvement; initial; injury; intervention; intracranial; ischemic; left; levels; management; mean; median; medical; monitoring; mortality; mri; mrs; neurocritical; new; non; outcome; patients; post; pressure; primary; rate; related; results; review; risk; sah; sah patients; scale; score; seizures; status; stroke; stroke patients; studies; study; subarachnoid; tbi patients; test; therapeutic; therapy; time; total; treatment; ttm; unit; use; vasospasm; years cache: cord-006182-kck5e1ry.txt plain text: cord-006182-kck5e1ry.txt item: #37 of 449 id: cord-006226-fn7zlutj author: None title: Abstracts of the 4th annual meeting of the German Society of Clinical Pharmacology and Therapy: Hannover, 14–17 September 1994 date: 1994 words: 25130 flesch: 47 summary: The effects were correlated with the %-~l-adrenoceptor occupancies estimated using a standard Emax-model (sigmoidicity=l) from the concentrations of active substrate in plasma determined by I~l-adrenoceptor specific radioreceptor assay. With regard to group I) the highest expenditures nccured in hospitals A and B whereas drug costs in C -E were 1/3 less and came to only 20% in hospital F. keywords: acid; activity; aggregation; blood; cell; clinical; concentrations; cost; data; disease; dose; drug; effects; excretion; function; group; hours; human; inhibition; mean; metabolites; method; min; patients; placebo; plasma; platelet; products; protein; rate; release; results; samples; serum; studies; study; therapy; time; total; treatment; urinary; urine; use; vitro; volunteers cache: cord-006226-fn7zlutj.txt plain text: cord-006226-fn7zlutj.txt item: #38 of 449 id: cord-006229-7yoilsho author: None title: Abstracts of the 82(nd) Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) and the 18(th) Annual Meeting of the Network Clinical Pharmacology Germany (VKliPha) in cooperation with the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e.V. (AGAH) date: 2016-02-06 words: 134020 flesch: 40 summary: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by a metabolic shift towards enhanced aerobic glycolysis and hence, increased lactate production. Further studies will be performed to clarify whether silver ions and/or silver nanoparticles could affect the specific N-acetylation of arylamines in human cells. keywords: acid; activation; activity; addition; agents; agonist; aim; analysis; animal; anti; approach; assay; assessment; background; barrier; binding; blood; body; brain; camp; cancer; cancer cells; cardiac; cell death; cell line; cells; cgmp; changes; channels; chemical; chronic; clinical; complex; compounds; concentrations; conclusion; conditions; contrast; control; culture; current; damage; data; days; death; development; differences; different; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; experiments; exposure; expression; factor; fibroblasts; findings; flow; fold; food; formation; fret; function; g protein; gene; germany; group; growth; health; heart; human; impact; increase; induction; inflammation; influence; inhibition; inhibitors; insulin; interaction; intracellular; kidney; levels; line; liver; loss; low; lung; mcpd; mechanisms; membrane; metabolism; metabolites; methods; mice; migration; model; mouse; mrna; nanoparticles; neurons; new; non; novel; number; oct1; order; p<0.05; parameters; pathways; patients; phosphorylation; plasma; platelet; potential; presence; present; primary; processes; products; proliferation; properties; protein; protein expression; rats; receptor; receptor activation; reduced; reduction; regulation; release; research; resistance; response; results; risk; role; samples; set; signaling; skin; small; specific; stimulation; stress; studies; study; substances; system; target; test; testing; therapy; time; tissue; total; toxicity; transcription; treatment; tumor; type; uptake; vitro; vivo; vs.; weight cache: cord-006229-7yoilsho.txt plain text: cord-006229-7yoilsho.txt item: #39 of 449 id: cord-006230-xta38e7j author: None title: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V. date: 2012-02-22 words: 136000 flesch: 40 summary: In in-vitro studies on rat and canine mast cells and human mast cell leukemia cells HMC1.2 BZ at micromolar concentrations inhibited mediator release which appeared to be related to an inhibition of the intracellular cAMP pathway. Previous work showed that mouse cells lacking the immediate-early gene c-fos are hypersensitive to ultraviolet (UVC) light. keywords: acid; activation; activity; acute; addition; adducts; agonist; aim; analysis; animals; anti; apoptosis; approach; assay; assessment; binding; blood; brain; calcium; camp; cancer; cancer cells; cardiac; cell line; cells; cellular; cgmp; changes; channels; chronic; clinical; complex; compounds; concentration; conclusion; conditions; contrast; control; current; damage; data; days; death; decrease; deficient; development; differences; differentiation; disease; dna; dose; drug; e.g.; effects; endothelial; enzyme; evidence; experiments; exposure; expression; factor; failure; family; fibroblasts; findings; fold; food; formation; function; für; g protein; gene; gene expression; germany; glucose; growth; health; heart; human; hypertrophy; increase; induction; inflammation; inhibition; inhibitors; institut; insulin; interaction; intracellular; kidney; kinase; leads; levels; like; line; liver; loss; low; lung; macrophages; mechanisms; membrane; methods; mice; model; mouse; mrna; muscle cells; mutations; nanoparticles; ndpk; non; novel; number; pain; pathway; patients; pcr; pharmakologie; phosphorylation; plasma; potential; presence; present; pressure; primary; processes; production; products; proliferation; promoter; properties; protein; protein expression; pulmonary; rats; receptor; reduced; regulation; release; response; results; risk; rkip; role; ros; samples; selective; signaling; site; skin; smooth; specific; stimulation; stress; studies; study; substances; subunits; synthesis; system; t cells; target; test; tested; therapy; time; tissue; toxicity; toxikologie; toxin; transcription; transport; treatment; tumor; tumor cells; type; universität; uptake; values; vascular; vitro; vivo; water cache: cord-006230-xta38e7j.txt plain text: cord-006230-xta38e7j.txt item: #40 of 449 id: cord-006391-esnsa4u5 author: None title: Abstracts 5(th) Tripartite Meeting Salzburg/Austria, September 9–11,1982 date: 1982 words: 44873 flesch: 47 summary: Control patients (no ASA) were compared to those receiving 80 or 325 mg. After transplantation patients were followed for a minimum of 3 months and a maximum of 42 months. keywords: acid; activity; acute; animals; bile; blood; blood flow; body; bypass; cases; cells; changes; control; days; dogs; duct; effect; failure; flow; gastric; glucose; graft; group; heart; hepatic; increase; infusion; insulin; kidney; levels; liver; mean; method; min; months; non; normal; operation; patients; plasma; postoperative; present; pressure; rate; rats; rejection; response; results; serum; studies; study; surgery; survival; time; tissue; total; transplantation; treatment; tumor; values; vascular; weeks; weight cache: cord-006391-esnsa4u5.txt plain text: cord-006391-esnsa4u5.txt item: #41 of 449 id: cord-006563-qmigctkp author: None title: The abstracts of the 26th congress of ESCTAIC, Timisoara, Romania, September 22–24 2016 date: 2017-03-07 words: 8635 flesch: 41 summary: The increase in lung volumes has been demonstrated by impedance plethysmography in post-cardiac surgical patients (Corley et al., 2011) . Current studies contain data with relatively small groups of patients. keywords: anesthesia; anesthesiologist; block; care; data; device; effects; emergency; group; incident; information; management; nerve; operating; pain; patients; simulation; study; surgery; system; time; use cache: cord-006563-qmigctkp.txt plain text: cord-006563-qmigctkp.txt item: #42 of 449 id: cord-006636-xgikbdns author: Ühlein, E. title: Übersicht Über neue ernährungswissenschaftliche Publikationen date: 1964-02-01 words: 31083 flesch: 47 summary: im Liehte der mathematisehen Analyse der Bestimmungen der Fleischbcschau yon Schweinefleisch mSglieh? zur Bestimmung der Gesamtjodzahl yon keywords: 1963; absorption; abstr; acid; acid composition; acid metabolism; activity; amino; amino acid; analysis; arch; auf; beef; bei; bei der; bestimmung; blood; body; calcium; carbohydrate; changes; chemical; chick; children; cholesterol; comparison; composition; content; corn; cows; dairy; deficiency; den; der; des; determination; development; die; diet; digestibility; effect; egg; energy; ern; evaluation; excretion; factors; fat; fats; fatty; fed; feeding; feeds; fiber; fish; flour; food; fruit; glucose; growth; hrung; human; influence; intake; iron; lebensmittel; levels; lipids; liver; low; magnesium; malnutrition; meat; metabolism; method; milch; milk; nitrogen; nutrient; nutrition; nutritive; oil; performance; phosphorus; pigs; plant; plasma; potassium; poultry; production; products; protein; quality; r. s.; rats; relation; relationship; requirements; residues; response; s. s.; serum; sheep; sodium; storage; studies; study; temperature; tissue; und; untersuchungen; use; utilization; value; van; vitamin; water; wheat; wirkung; wiss; yon; zinc; zum; zur cache: cord-006636-xgikbdns.txt plain text: cord-006636-xgikbdns.txt item: #43 of 449 id: cord-006702-ekf6mja9 author: None title: Abstracts for the 17th IPNA Congress, Iguaçu, Brazil, September 2016: Oral Presentations date: 2016-08-17 words: 23283 flesch: 45 summary: Conclusions: CKD patients have modifiable risk factors for intimal and medial vascular disease which were not detected by CUS. Among the transplant patients, the percent of patients achieving seropositivity was significantly lower at blood draw 2 for HPV genotypes 6 (63.6%, p=0.003), 11 (63.6%, p=0.003) and 18 (72.7%, p=0.02) and blood draw 3 for HPV genotypes 6 (62.5%, p=0.02), 11 (50%, p=0.001), 16 (75%, p=0.04), and 18 (50%, p=0.001). & Whiskers represent the 25th or 75th percentiles + (1.5x Interquartile Range) Antibody levels in transplant patients compared to CKD patients and to dialysis patients for HPV genotypes 6, 11, 16, 18 . keywords: age; analysis; associated; blood; cell; children; chronic; ckd; cohort; conclusions; data; days; dialysis; disease; dose; fgf23; follow; group; growth; kidney; levels; mean; median; methods; model; months; mutations; objectives; patients; pediatric; pts; renal; results; risk; stage; study; syndrome; therapy; time; transplant; treatment; university; urine; vur; years cache: cord-006702-ekf6mja9.txt plain text: cord-006702-ekf6mja9.txt item: #44 of 449 id: cord-006849-vgjz74ts author: None title: 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date: 2019-09-13 words: 222539 flesch: 45 summary: Day after surgery patient was asymptomatic, got full oral diet. Methods: From January 2001 to March 2005 all characteristics of surgical patients with diverticular and colon adenocarcinoma colovesical fistulae were reviewed. keywords: abdominal; acute; age; aim; aims; analysis; anastomosis; anatomy; anterior; approach; artery; associated; average; background; bile; biliary; bleeding; blood; bmi; body; bowel; bypass; cancer patients; cancer surgery; cases; cholecystectomy; chronic; clinical; closure; colon; complete; complications; conclusion; control; conventional; conversion; course; data; days; defect; diagnosis; differences; disease; dissection; distal; drainage; duct; emergency surgery; endoscopic; esophageal; esophagus; evaluation; examination; experience; factors; female; fluorescence; follow; following; gastrectomy; gastric; general; good; grade; group; hepatic; hernia; history; hospital; icg; imaging; incision; intervention; intraoperative; introduction; laparoscopic; leak; learning; left; lesion; level; line; liver; loss; lymph; management; mass; mean; median; medical; mesh; methods; model; months; morbidity; mortality; need; new; node; non; normal; number; objective; open; operation; operation time; order; outcomes; p =; pain; patients; perform; period; port; position; postoperative; preoperative; present; primary; procedure; quality; rate; recurrence; reflux; repair; report; resection; results; right; risk; risk patients; robotic; safety; scan; score; short; size; sleeve; space; stage; standard; stay; step; stomach; studies; study; study group; surgeons; surgery; surgery group; surgery patients; surgical; survival; suture; symptoms; system; technique; term; time; tissue; total; training; treatment; tumor; type; use; video; wall; weight; years cache: cord-006849-vgjz74ts.txt plain text: cord-006849-vgjz74ts.txt item: #45 of 449 id: cord-006854-o2e5na78 author: None title: Scientific Session of the 16th World Congress of Endoscopic Surgery, Jointly Hosted by Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) & Canadian Association of General Surgeons (CAGS), Seattle, Washington, USA, 11–14 April 2018: Poster Abstracts date: 2018-04-20 words: 166333 flesch: 44 summary: Here we were able to demonstrate that the procedure can be safely used in laparoscopic surgery patients. On bivariate analysis, robotic-assist patients had a higher rate of readmission than laparoscopic patients (7.5% vs. 6.4%; P=.03), but no differences in 30-day reoperation ( Conclusion: Robotic-assistance does not confer an increased rate of morbidity and mortality after RYGB, and represents a feasible surgical modality for the surgeon willing to adopt the technology and accept its limitations. keywords: acute; age; aim; analysis; anastomosis; approach; assessment; assisted; average; background; bile; biliary; bleeding; blood; bmi; bowel; bypass; cancer; cancer patients; cancer surgery; care; cases; center; cholecystectomy; clinical; colon; colorectal; complications; conclusion; control; conversion; data; days; diagnosis; difference; disease; dissection; endoscopic; esophageal; evaluation; experience; factors; female; follow; following; gallbladder; gastrectomy; gastric; general; gerd; group; hernia; hernia repair; hiatal; history; hospital; icg; imaging; incidence; incision; index; injury; institution; introduction; laparoscopic; leak; left; length; level; literature; liver; loss; lsg; lymph; management; mass; mean; median; medical; mesh; methods; minutes; months; morbidity; mortality; non; number; obesity; objective; obstruction; operation; operative; outcomes; pain; pancreatic; patients; performance; period; placement; postoperative; preoperative; present; primary; prior; procedure; quality; range; rate; recurrence; repair; report; resection; residents; results; retrospective; review; right; risk; robotic; rygb; safety; score; series; site; skills; sleeve; stage; standard; stay; stomach; studies; study; surgeons; surgery; surgery patients; surgical; symptoms; system; technique; term; test; time; tissue; total; training; treatment; tumor; type; university; use; wall; weight; years cache: cord-006854-o2e5na78.txt plain text: cord-006854-o2e5na78.txt item: #46 of 449 id: cord-006860-a3b8hyyr author: None title: 40th Annual Meeting of the GTH (Gesellschaft für Thrombose- und Hämostaseforschung) date: 1996 words: 90772 flesch: 46 summary: The data show that children with low risk did in part receive higher doses of heparin and/or AT III concentrate than did high risk patients, whereas plasma therapy was adjusted to severity of eoagnlopathy. Inhibitor testing was done on patients plasma samples using the Bethesda method. keywords: activation; activity; acute; addition; age; agents; aggregation; analysis; antibodies; anticoagulant; anticoagulation; antigen; antithrombin; apc; aptt; assay; binding; bleeding; blood; blood coagulation; blood samples; cases; cells; children; clinical; clotting; coagulation; coagulation factor; complex; complications; concentrations; conclusion; contrast; control; coronary; correlation; count; data; day; days; deficiency; diagnosis; disease; dose; effect; elevated; endothelial; events; expression; factor; factor v; factor viii; family; fibrin; fibrinogen; formation; group; heparin; hirudin; hours; human; incidence; increase; influence; infusion; inhibitor; inr; laboratory; levels; low; mean; median; method; months; mutation; normal; order; parameters; patients; period; phase; plasma; plasma samples; plasminogen; platelet; platelet activation; platelet factor; present; products; protein; protein c; prothrombin; pts; range; reagent; receptor; reduced; release; resistance; response; results; risk; risk factor; role; samples; specific; studies; study; surface; surgery; system; test; therapy; thrombin; thrombosis; time; tissue; total; treatment; type; use; values; vascular; vein; venous; viii; vwf; weight; years cache: cord-006860-a3b8hyyr.txt plain text: cord-006860-a3b8hyyr.txt item: #47 of 449 id: cord-006862-5va1yyit author: None title: ITS ASM 2012 date: 2012-11-04 words: 26008 flesch: 50 summary: A questionnaire was sent to relevant members of the Exercise has been shown to improve quality of life in respiratory patients. Conclusion: A significant percentage of respiratory patients lack adequate knowledge of their respiratory medication; this is despite a majority having previously been educated on this medication. keywords: aat; aatd; age; analysis; asthma; cancer; cases; chest; clinic; copd; copd patients; data; diagnosis; disease; group; history; hospital; inhaler; ipf; levels; lung; lung disease; male; mean; months; n =; negative; non; osas; p =; patients; pulmonary; respiratory; results; sarcoidosis; score; smoking; study; therapy; treatment; years cache: cord-006862-5va1yyit.txt plain text: cord-006862-5va1yyit.txt item: #48 of 449 id: cord-006864-t5qsjyfi author: Norris, S. title: National scientific medical meeting 1995 abstracts: Oral presentations date: 1995 words: 36498 flesch: 51 summary: X 100 birth weight (g) or birth head circumference (cm) divided by the age in weeks and expressed as % per weekhead index (HI) and weight index (WI). Home interviews suggest 31.1% Suicidal Ideation ever, 2.7% Self-harm rate -4% of those interviewed felt suicide was a right under adverse circumstances. keywords: a. a.; a. g.; a. j.; activity; age; analysis; blood; c. a.; c. j.; c. m.; c. t.; cases; cells; control; d. a.; d. c.; d. d.; d. j.; d. p.; data; disease; evidence; expression; fitzgerald; g. d.; g. j.; g. m.; group; hospital; increase; infection; j. f.; j. j.; j. s.; k. d.; levels; m. a.; m. j.; mean; non; p. a.; p. j.; p. p.; patients; period; pregnancy; prevalence; range; rate; results; risk; samples; study; subjects; therapy; time; treatment; v. j.; years cache: cord-006864-t5qsjyfi.txt plain text: cord-006864-t5qsjyfi.txt item: #49 of 449 id: cord-006870-f5w6fw6q author: None title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 words: 122395 flesch: 46 summary: The best model fit was for good outcome (modified Rankin Score 0-2 equivalents) based on % patients with WFNS 4-5 and age (R2=0.54; p<0.001). Decreasing time spent in cervical spinal immobilization could improve patient care by allowing greater access to / range-of-motion of the neck, increasing patient comfort, and decreasing skin breakdown. keywords: acute; administration; admission; adult patients; analysis; arrest; asah; associated; baseline; blood; brain; brain injury; cardiac; care patients; care unit; case; center; cerebral; cohort; common; complications; data; days; death; diagnosis; difference; discharge; duration; early; edema; eeg; effect; epilepticus; evd; factors; findings; following; gcs; group; head; hematoma; hemorrhage; hemorrhage patients; hospital; hours; ich; ich patients; icp; icu; identified; imaging; improvement; infusion; initial; injury; intracerebral; intracranial; ischemic; left; level; los; management; mean; median; medical; minutes; model; monitoring; months; mortality; mri; neurocritical; new; non; number; outcome; patients; period; placement; population; post; presence; present; pressure; primary; prior; prospective; rate; refractory; related; report; results; review; right; risk; risk patients; sah patients; scale; score; secondary; seizures; srse; status; stay; stroke patients; studies; study; subarachnoid; surgery; tbi; tbi patients; test; therapy; time; total; treatment; unit; use; years cache: cord-006870-f5w6fw6q.txt plain text: cord-006870-f5w6fw6q.txt item: #50 of 449 id: cord-006876-v2m5l5wz author: None title: Neurocritical Care Society 14(th) Annual Meeting date: 2016-08-11 words: 59827 flesch: 46 summary: However, the trend was not uniform -48% patients had no correlation between rSO2 and CPP, 29% showed a positive correlation and 23% showed a negative correlation. Major reasons for satisfaction included: physician response to emergencies, physician -nurse communication, and patient outcome. keywords: acute; admission; analysis; arrest; asah; associated; baseline; blood; brain; brain injury; cardiac; care; care patients; care unit; case; center; cerebral; cohort; complications; data; days; death; developed; discharge; dose; duration; eeg; following; gcs; group; hemorrhage; hospital; hours; ich; ich patients; icp; icu; impact; injury; intensive; intracranial; management; mean; median; medical; model; monitoring; months; mortality; neurocritical; neurological; new; non; onset; outcome; patients; pcc; post; pressure; primary; rate; results; review; sah; sah patients; score; seizures; status; studies; study; subarachnoid; tbi; therapy; time; total; treated; treatment; unit; use; years cache: cord-006876-v2m5l5wz.txt plain text: cord-006876-v2m5l5wz.txt item: #51 of 449 id: cord-006880-9dgmdtj8 author: None title: Neurocritical Care Society 10th Annual Meeting: October 4 - 7, 2012 Sheraton Denver Downtown Hotel Denver, Colorado date: 2012-09-19 words: 82474 flesch: 47 summary: Included patients were 55.5 ±15.2 years old with female preponderance (65.5%, (76/116)). Admission NIHSS was 11 for ICU patients and 9 for SU patients (NS). keywords: acute; admission; adult patients; analysis; aneurysm; arrest; arrest patients; asah; blood; brain; brain injury; cardiac; care; case; center; cerebral; cohort; coma; complications; data; days; dci; death; diagnosis; discharge; early; factors; following; gcs; good; group; head; hemorrhage; high; hospital; hours; hypothermia; ich; icp; icu; icu patients; imaging; increase; initial; injury; intracranial; ischemic; levels; management; mean; median; medical; monitoring; mortality; mri; mrs; neurocritical; non; onset; outcome; patients; poor; post; present; pressure; rate; regression; results; review; risk; sah; sah patients; scale; score; status; stroke patients; studies; study; subarachnoid; surgical; tbi; tbi patients; therapeutic; therapy; time; total; traumatic; treatment; unit; use; vasospasm; vs.; years cache: cord-006880-9dgmdtj8.txt plain text: cord-006880-9dgmdtj8.txt item: #52 of 449 id: cord-006882-t9w1cdr4 author: None title: Royal Academy of Medicine in Ireland date: 2012-07-22 words: 13737 flesch: 50 summary: Older patients have lower lean muscle mass and therefore using serum creatinine alone as marker of renal function can lead to underdiagnosis of CKD. Due of the favourable prognosis with this type of tumour, MTSCC must be differentiated from papillary renal cell carcinoma to avoid administration of excessive adjuvant treatment to patients. keywords: audit; bone; case; complications; data; day; diabetes; disease; guidelines; hospital; management; patients; period; practice; prescribing; prevalence; results; study; surgery; therapy; time; treatment; use; women; year cache: cord-006882-t9w1cdr4.txt plain text: cord-006882-t9w1cdr4.txt item: #53 of 449 id: cord-006888-qfnukav4 author: None title: Irish Thoracic Society Annual Scientific Meeting, Ramada Hotel, Belfast: 7th–8th November 2008 date: 2008-10-21 words: 30386 flesch: 51 summary: We determined the frequency of HSV-1 in COPD patients (stable and exacerbated) and if it was associated with disease severity and mortality. Methods: Stable and exacerbated COPD patients were recruited. keywords: activity; age; aim; analysis; associated; asthma; cancer; care; cells; children; copd; copd patients; data; diagnosis; disease; effect; exercise; female; fev1; function; group; guidelines; hospital; levels; lung; male; management; mean; n =; non; p =; patients; population; pulmonary; range; respiratory; results; service; sleep; smoking; study; therapy; time; treatment; years cache: cord-006888-qfnukav4.txt plain text: cord-006888-qfnukav4.txt item: #54 of 449 id: cord-007321-7gi6xrci author: Chow, Anthony W. title: Evaluation of New Anti-Infective Drugs for the Treatment of Respiratory Tract Infections date: 1992-11-17 words: 16092 flesch: 29 summary: In phase 2 and 3 trials, study patients should be stratified according to major host factors (e.g., history and duration of smoking). Clinical studies should include patients of different age groups, since the clinical manifestations of group A streptococcal pharyngitis and tonsillitis may vary with age of the patient. keywords: acute; aom; children; chronic; control; culture; days; diagnosis; drug; evaluation; failure; group; infection; microbiologic; pathogens; patients; pharyngitis; pneumonia; response; sinusitis; sputum; studies; study; symptoms; therapy; treatment cache: cord-007321-7gi6xrci.txt plain text: cord-007321-7gi6xrci.txt item: #55 of 449 id: cord-007818-jfp9uumb author: Papali, Alfred title: Infrastructure and Organization of Adult Intensive Care Units in Resource-Limited Settings date: 2019-02-09 words: 15076 flesch: 28 summary: We suggest that, if possible, ICUs use a closed-format model where physicians specifically trained or experienced in intensive care medicine direct patient care (2B). Controlled trial of upper room ultraviolet air disinfection: a basis for new dosing guidelines Guidelines for prevention of hospital acquired infections Guide to local production: WHO-recommended handrub formulations Shelf-life of chlorine solutions recommended in Ebola virus disease response Cost-effectiveness of a hand hygiene program on health care-associated infections in intensive care patients at a tertiary care hospital in Vietnam Cluster-randomized, crossover trial of the efficacy of plain soap and water versus alcohol-based rub for surgical hand preparation in a rural hospital in Kenya Muslim health-care workers and alcoholbased handrubs Current practices and barriers to the use of facemasks and respirators among hospital-based health care workers in Vietnam A cluster randomised trial of cloth masks compared with medical masks in healthcare workers Infection prevention and control (IPC) guidance summary: Ebola guidance package An approach to prioritization of medical devices in low-income countries: an example based on the Republic of South Sudan Determining the utility and durability of medical equipment donated to a rural clinic in a low-income country Mortality rates increase dramatically below a systolic blood pressure of 105-mm Hg in septic surgical patients Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial International study on microcirculatory shock occurrence in acutely ill patients Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3) Diagnosing acute respiratory distress syndrome in resource limited settings: the Kigali modification of the Berlin definition Hypoxaemia as a mortality risk factor in acute lower respiratory infections in children in low and middle-income countries: systematic review and meta-analysis Prevalence and predictors of hypoxaemia in respiratory and non-respiratory primary diagnoses among emergently ill children at a tertiary hospital in south western Nigeria Single deranged physiologic parameters are associated with mortality in a low-income country Severely deranged vital signs as triggers for acute treatment modifications on an intensive care unit in a lowincome country Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scaleup: a longitudinal cohort study Dynamic measurement of hemodynamic parameters and cardiac preload in adults with dengue: a prospective observational study Vital signs directed therapy: improving care in an intensive care unit in a low-income country Accuracy of oscillometric blood pressure measurement according to the relation between cuff size and upper-arm circumference in critically ill patients Tracking hypotension and dynamic changes in arterial blood pressure with brachial cuff measurements Results of a survey of blood pressure monitoring by intensivists in critically ill patients: a preliminary study Pulse oximetry for perioperative monitoring The use of the pulse oximetric saturation/fraction of inspired oxygen ratio for risk stratification of patients with severe sepsis and septic shock Ventilatory support of patients with sepsis or septic shock in resource-limited settings The use of portable ultrasound devices in low-and middle-income countries: a systematic review of the literature Impact of improved vaccination programme and intensive care facilities on incidence and outcome of tetanus in southern Vietnam Neonatal tetanus in Vietnam: comprehensive intensive care support improves mortality Impact of a structured ICU training programme in resource-limited settings in Asia Non-invasive ventilation for children with acute respiratory failure in the developing world: literature review and an implementation example Noninvasive mechanical ventilation: an 18-month experience of two tertiary care hospitals in north India A randomized clinical trial evaluating nasal continuous positive airway pressure for acute respiratory distress in a developing country Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial Use of nasal bubble CPAP in children with hypoxemic clinical pneumonia-report from a resource limited set-up Efficacy of a lowcost bubble CPAP system in treatment of respiratory distress in a neonatal ward in Malawi Continuous end-tidal carbon dioxide monitoring in pediatric intensive care units The use of end-tidal carbon dioxide monitoring to confirm endotracheal tube placement in adult and paediatric intensive care units in Australia and New Zealand keywords: blood; care; countries; critical; equipment; hand; healthcare; hospital; hygiene; icu; icus; infection; intensive; medicine; mortality; national; oxygen; patients; quality; resource; sepsis; settings; studies; study; supply; training; use cache: cord-007818-jfp9uumb.txt plain text: cord-007818-jfp9uumb.txt item: #56 of 449 id: cord-007890-bie1veti author: None title: ECC-4 Abstracts date: 2002-04-16 words: 86133 flesch: 45 summary: On the whole, E. coli showed an elevated sensitivity rate ( !/90% of tested strains) to nitrofurantoin, gentamicin, amikacin, and 2nd-and 3rd-generation cephalosporins, while only amoxicillin and piperacillin had a mean resistance rate !/30 % for M41L, D67N, K103N, M184V, L210W, T215YF, and for L10I, M36I, L63P, A71VT, L90M for P Inhibitors (PI). keywords: acid; activity; acute; administration; aeruginosa; agar; agents; aim; amoxicillin; analysis; antibiotic; antimicrobial; associated; aureus; b b; bacteria; beta; blood; candida; care; cases; cells; children; chronic; ciprofloxacin; clinical; coli; combination; concentrations; conclusion; control; cultures; data; days; department; diagnosis; disease; dna; dose; drug; effect; efficacy; erythromycin; esbl; fever; following; france; general; gentamicin; gram; group; haart; hcv; health; hepatitis; high; hiv; hospital; human; ifn; imipenem; incidence; infected; infection; influenza; institute; isolates; l b; laboratory; level; linezolid; mean; medical; medicine; methods; microbiology; mics; months; mrsa; nccls; negative; new; non; nosocomial; number; oral; patients; pcr; penicillin; period; plasma; pneumoniae; positive; presence; present; prevalence; pts; purpose; rate; resistance; results; risk; rna; samples; school; sensitivity; serum; spain; species; specific; spp; staphylococcus; strains; streptococcus; study; susceptibility; system; teicoplanin; tested; therapy; time; tissue; total; tract; treatment; university; urinary; urine; use; vancomycin; virus; vitro; years cache: cord-007890-bie1veti.txt plain text: cord-007890-bie1veti.txt item: #57 of 449 id: cord-008777-i2reanan author: None title: ECB12: 12th European Congess on Biotechnology date: 2005-07-19 words: 151661 flesch: 40 summary: During the process development for protein production, short time to market and the demand for cheap processes dominate today's process development. Interdependence of the impact of methanol and oxygen supply on protein production with recombinant Pichia pastoris N.K. Khatri, F. Hoffmann Martin-Luther-University Halle-Wittenberg, Institute for Biotechnology, Halle D-06120, Germany. keywords: acid; acid production; activities; activity; addition; adsorption; affinity; aim; alternative; amino; analysis; animal; ankara; antibody; application; applied; approach; assay; bacillus; bacteria; batch; bed; binding; biology; biomass; bioreactor; biosynthesis; biotechnology; capacity; carbon; case; cell; cell growth; cerevisiae; changes; chemical; chitosan; chromatography; coli; column; complex; composition; compounds; concentration; conditions; control; conversion; cost; cultivation; culture; data; days; degradation; denmark; department; design; development; differences; different; disease; dna; e.g.; effect; efficiency; energy; engineering; environmental; enzymatic; enzyme; enzyme activity; enzyme production; ethanol; ethanol production; experiments; expression; extract; factors; fed; fermentation; fermentation process; flow; flux; food; formation; function; gel; gene; gene expression; genome; glucose; group; growth; health; high; host; human; hydrolysis; identification; increase; induction; industrial; industry; influence; institute; interest; intracellular; knowledge; laboratory; level; limited; line; lipase; liquid; mail; mass; maximum; media; medium; metabolic; metabolites; method; microbial; microorganisms; milk; model; molecular; molecules; natural; network; new; niger; nitrogen; non; novel; number; oil; operation; optimization; order; oxygen; parameters; pathway; pcr; peptide; performance; phase; phosphate; plant; plasmid; potential; presence; present; procedure; process; processes; produce; production; production process; productivity; products; project; properties; protein; protein expression; protein production; purification; quality; range; rate; reaction; recombinant; regulation; removal; research; response; resulting; results; role; samples; scale; science; screening; separation; sequence; signal; source; species; specific; stability; state; step; strains; stress; structure; studies; study; substrate; sucrose; sugar; surface; synthesis; system; target; technical; technique; temperature; therapy; time; total; transfer; treatment; turkey; type; university; use; value; vitro; water; weight; work; yeast; yield cache: cord-008777-i2reanan.txt plain text: cord-008777-i2reanan.txt item: #58 of 449 id: cord-009571-mygj2nd4 author: None title: Proceedings of the 42nd annual meeting of the american rheumatism association a section of the arthritis foundation june 1 & 2, 1978 new york city abstracts of papers presented date: 2005-11-23 words: 46205 flesch: 47 summary: Ten of 11 boys had disease onset prior to sexual maturation, whereas disease began after menarche in ADCC activity between patient cells and control cells when either the mixed mononuclear population or monocyte-depleted population were studied as effectors. Urate clear-ance appears to be the major determinant of serum uric acid concentration even in sickle cell patients with urate overproduction. keywords: acid; activity; anti; antibodies; antibody; antigen; arthritis; assay; binding; blood; bone; cartilage; cells; changes; complement; complexes; control; disease; dna; erythematosus; fluid; group; high; human; igg; igm; immune; joint; levels; lupus; lymphocytes; mean; mice; months; negative; normal; patients; positive; presence; present; renal; response; results; rheumatoid; sera; serum; sle; sle patients; studies; study; synovial; tissue; treatment; type; urate; years cache: cord-009571-mygj2nd4.txt plain text: cord-009571-mygj2nd4.txt item: #59 of 449 id: cord-009664-kb9fnbgy author: None title: Oral presentations date: 2014-12-24 words: 71226 flesch: 44 summary: Resistance to penicillin, clindamycin and tetracycline fluctuated over time at~75%, 4−8% and 2−10% respectively. The median expected power was 10.0% (IQR, 7.2−13.6%) for a risk ratio for mortality of 0.85 between the compared groups; 14.7% (IQR, 10.6−21.8%) for a risk ratio of 0.80; and 7.9% (IQR, 6.3−10.2%) for a reduction in mortality from 30% to 25%. keywords: age; analysis; antibiotic; assay; associated; aureus; bacterial; blood; cases; cause; cdi; cells; clinical; common; community; conclusion; control; countries; culture; data; days; detection; diagnosis; different; difficile; disease; dna; drug; efflux; europe; expression; factors; gene; group; high; hospital; human; identification; incidence; increase; infections; influenza; isolates; laboratory; levels; like; methods; microbiology; model; mortality; mrsa; n =; negative; new; non; number; objectives; pathogens; patients; pcr; period; plasmid; pneumoniae; population; positive; potential; presence; present; prevalence; pvl; range; rate; resistance; resistance genes; response; results; risk; role; samples; screening; sensitivity; sequence; species; specimens; spread; strains; studies; study; susceptibility; system; testing; therapy; time; total; treatment; type; use; virus; years cache: cord-009664-kb9fnbgy.txt plain text: cord-009664-kb9fnbgy.txt item: #60 of 449 id: cord-009713-sxd4t2tz author: None title: Poster Presentations date: 2020-01-10 words: 44058 flesch: 48 summary: Long-term safety and efficacy of adjunctive perampanel in paediatric patients (aged 4 to <12y) with partial-onset seizures (POS) or primary generalised tonic-clonic seizures (PGTCS) in Study 311 R FLAMINI 1 , A PATTEN 2 , LY NGO 3 1 Pediatric and Adolescent Neurodevelopmental Associates, Atlanta, GA, USA; 2 Eisai Ltd., Hatfield, Hertfordshire, UK; 3 Eisai Inc., Woodcliff Lake, NJ, USA Objective: Study 311 (NCT02849626) was a multicentre, openlabel, single-arm study of perampanel oral suspension (0.5mg/ mL) in paediatric patients (aged 4 to <12y) with POS (with/ without secondarily generalised seizures Here, we report long-term (1y) safety and efficacy data of adjunctive perampanel in paediatric patients from Study 311. keywords: acute; age; analysis; associated; brain; care; cases; children; cohort; conclusions; data; day; days; delay; developmental; diagnosis; disease; disorder; dystonia; eeg; epilepsy; features; following; function; gene; group; history; hospital; imaging; investigations; management; mean; median; methods; months; motor; mri; mutation; neurology; non; normal; objective; onset; outcomes; paediatric; parents; patients; poster; presentation; range; report; results; review; seizures; study; symptoms; syndrome; term; time; treatment; weakness; weeks; years cache: cord-009713-sxd4t2tz.txt plain text: cord-009713-sxd4t2tz.txt item: #61 of 449 id: cord-009997-oecpqf1j author: None title: 2018 ASPHO ABSTRACTS date: 2018-03-31 words: 182444 flesch: 45 summary: Of included patients, 165 had treatment intensity of 2 (41.0%), 192 of 3 (47.8%) and 45 of 4 (11.2%). After 2 cycles of treatment patient was no longer requiring oxygen and was ambulating without assistance. keywords: acute; addition; adherence; adult patients; age; aml; aml patients; analysis; anemia; anti; average; background; baseline; biopsy; bleeding; blood; blood cell; bone; cancer; cancer patients; care; cases; cell; cell disease; center; chart; chemotherapy; childhood; children; chronic; clinical; cohort; complications; conclusion; control; count; course; cycles; data; days; death; design; development; diagnosis; differences; disease; dose; effects; efficacy; end; episodes; evaluation; events; evidence; expression; factors; failure; family; female; fever; findings; following; function; gene; grade; group; guidelines; health; hemoglobin; high; history; hospital; hsct patients; hydroxyurea; imaging; immune; impact; improvement; incidence; increase; induction; infection; initial; institution; intervention; iron; laboratory; lesions; leukemia; levels; life; literature; liver; loss; low; lymphoma; male; management; marrow; mean; median; medical; metastatic; method; months; mortality; multiple; mutations; n =; need; negative; neuroblastoma; neuroblastoma patients; neutropenia; new; non; normal; novel; number; objectives; oncology patients; outcomes; p =; pain; parents; patients; pediatric; period; platelet; population; positive; post; potential; present; presentation; primary; program; providers; range; rates; relapse; report; required; research; response; results; review; risk; risk patients; role; scd patients; scores; screening; severe; sickle; sirolimus; specific; stage; standard; states; states background; stem; studies; study; support; survival; survivors; symptoms; syndrome; term; testing; therapy; thrombocytopenia; time; total; transfusion; transplant; treatment; tumor; type; united; use; weeks; years cache: cord-009997-oecpqf1j.txt plain text: cord-009997-oecpqf1j.txt item: #62 of 449 id: cord-010018-gl8uuqej author: Del Borrello, Giovanni title: New insights into pediatric community‐acquired pneumonia gained from untargeted metabolomics: A preliminary study date: 2019-12-10 words: 2360 flesch: 24 summary: In Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis Community-acquired pneumonia requiring hospitalization among U.S. children A systematic review on the diagnosis of pediatric bacterial pneumonia: when gold is bronze Antibiotic therapy for pediatric community-acquired pneumonia: do we know when, what and for how long to treat? Three recent metabolomic studies also found an increase in the urinary concentration of acyl-carnitines in patients with bacterial pneumonia. keywords: analysis; cap; children; community; etiology; infection; pneumonia; study cache: cord-010018-gl8uuqej.txt plain text: cord-010018-gl8uuqej.txt item: #63 of 449 id: cord-010027-r0tl01kq author: None title: Dublin Pathology 2015. 8th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland date: 2015-09-15 words: 36337 flesch: 44 summary: Tumoral melanosis refers to complete regression of a melanoma, a diagnosis that it is often missed because of the absence of tumour cells within the regressed area. Background: During the metastatic cascade, circulating tumour cells rapidly and efficiently adopt a platelet cloak. keywords: analysis; benign; biopsies; biopsy; breast; cancer; carcinoma; cases; cell; changes; data; diagnosis; digital; disease; dna; expression; features; findings; genes; grade; hospital; immunohistochemistry; lesions; lines; lung; lymphoma; melanoma; methods; molecular; mutations; negative; non; number; ovarian; pathology; patients; potential; practice; primary; protein; quality; report; resection; results; review; risk; role; samples; sequencing; specific; specimens; staining; status; study; survival; testing; time; tissue; treatment; tumour; use; years cache: cord-010027-r0tl01kq.txt plain text: cord-010027-r0tl01kq.txt item: #64 of 449 id: cord-010075-72jodunj author: None title: Paediatric SIG: Poster Session date: 2011-03-21 words: 32065 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-010075-72jodunj.txt plain text: cord-010075-72jodunj.txt item: #65 of 449 id: cord-010092-uftc8inx author: None title: Abstract of 29th Regional Congress of the ISBT date: 2019-06-07 words: 233543 flesch: 50 summary: One central question is the need of individual NAT screening (ID) versus minipool NAT screening (MP) approaches to identify all relevant viremias in blood donors. 3A-S02-03 Background: The screening of blood donors and returning travelers from active transmission areas have highlighted the importance of diagnosis of acute arboviral infections. keywords: abo blood; addition; aims; allele; alloimmunization; analysis; anemia; anti; antibodies; antibody; antigen; apheresis; approach; assay; available; average; background; bacterial; bleeding; blood bank; blood cells; blood center; blood chimerism; blood collection; blood components; blood count; blood culture; blood demand; blood donation; blood donors; blood establishments; blood flow; blood group; blood grouping; blood loss; blood management; blood plasma; blood platelet; blood pressure; blood processing; blood products; blood results; blood safety; blood samples; blood services; blood supply; blood system; blood test; blood transfusion; blood type; blood units; blood volume; care; cases; cause; cell donors; cell transfusion; clinical; concentrates; concentration; conclusions; confirmed; content; control; cord blood; countries; criteria; cross; current; data; day; days; deferral; detection; difference; disease; dna; donations; donor samples; effect; events; evidence; exon; expression; factors; female; ferritin; flow; following; frequency; gel; gene; genotyping; group system; groups; hbv; hcv; health; hemoglobin; hev; history; hiv; hla; hospital; hospital blood; human; identification; igg; impact; incidence; increase; individuals; infection; information; international; iron; laboratory; levels; life; low; major; mean; median; medical; methods; min; ml blood; model; molecular; months; n =; national; need; negative; new; non; number; order; overall; p =; patients; pcr; pcs; period; phenotype; plasma; plasma donors; plasma transfusion; platelet; platelet donors; platelet transfusion; population; positive; post; potential; practice; presence; present; prevalence; procedure; process; production; quality; quality blood; range; rate; rbc blood; rbc transfusion; rbcs; reactive; red; reduced; repeat donors; research; results; rhd; rhd blood; risk; routine; screening; selection; sequencing; serum; significant; specific; staff; standard; status; storage; studies; study; summary; surgery; systems; tested; testing; tests; therapy; time donors; total; transfusion medicine; transfusion reactions; transfusion safety; transfusion service; transfusion therapy; transfusions; treated; treatment; typing; use; value; variant; versus; weak; women; years cache: cord-010092-uftc8inx.txt plain text: cord-010092-uftc8inx.txt item: #66 of 449 id: cord-010119-t1x9gknd author: None title: Abstract Presentations from the AABB Annual Meeting San Diego, CA ctober 7‐10, 2017 date: 2017-09-04 words: 230433 flesch: 50 summary: Probability of occurrence of cannabis metabolites in blood donor samples is likely to be highly variable across donor centers and is largely dependent on blood donor demographics. OBRR, CBER, FDA Background/Case Studies: Extended molecular typing of a large number of blood donors can increase the likelihood of identifying donor red blood cells (RBCs) that match those of the recipient. keywords: abo; abo blood; acute; addition; alleles; alloimmunization; analysis; anemia; anti; antibodies; antibody; antigen; apheresis; approach; assay; average; background; bacterial; blood; blood bank; blood cells; blood center; blood collection; blood components; blood count; blood donation; blood donors; blood group; blood loss; blood management; blood order; blood ordering; blood products; blood safety; blood samples; blood screening; blood services; blood specimens; blood supplier; blood supply; blood system; blood testing; blood transfusion; blood type; blood units; blood volume; care; case studies; case study; cases; cd36; cell transfusion; center background; centers; change; clinical; collections; concentration; conclusion; control; cord blood; cost; count; cross; culture; current; data; days; decreased; detection; difference; disease; dna; donations; donor samples; dose; dtt; effect; emergency blood; evaluation; events; evidence; expression; factors; fda; female; ffp; finding; flow; following; frequency; fresh; gel; gene; genotyping; given; groups; hbv; hcv; health; hemoglobin; hemolysis; high; history; hiv; hla; hospital; hospital blood; hospital transfusion; hours; human; identification; igg; immucor; impact; implementation; improvement; incidence; increase; infection; information; initial; institution; inventory; iron; laboratory; levels; low; manual; mean; median; medical; method; mice; minutes; model; molecular; months; mtp; need; negative; new; non; normal; number; order; partial; pathogen; patients; pcr; performance; period; phase; phenotype; plasma; plasma samples; plasma transfusion; plasma units; platelet; platelet blood; platelet transfusion; platelet units; plt; plts; population; positive; post; post transfusion; potential; practice; pre; presence; present; prevalence; procedure; process; processing; program; protocol; quality; r blood; range; rate; rbc; rbc blood; rbc transfusion; rbc units; rbcs; reactive; reactivity; reagent; recipients; recovery; red; reduced; reduction; reference; report; response; results; review; rhd; risk; routine; screening; second; sensitivity; sequencing; serum; set; small; solution; specific; specificity; staff; standard; storage; study design; study period; survey; systems; table; technology; test results; testing; tests; therapy; time; titer; total; tpe; training; transfused; transfusion medicine; transfusion practice; transfusion protocol; transfusion reactions; transfusion results; transfusion service; transfusions; trauma; treatment; tube; typing; units; university; use; values; virus; wastage; wbc; weak; weeks; women; year; zika; zikv cache: cord-010119-t1x9gknd.txt plain text: cord-010119-t1x9gknd.txt item: #67 of 449 id: cord-010680-lc1onm53 author: Patel, Ami title: In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies date: 2020-03-10 words: 13069 flesch: 37 summary: The original studies surrounding in vivo antibody gene delivery focused primarily on gene delivery using recombinant viral vectors such as AAV and adenovirus (Ad), which were advanced clinically, building on work in the traditional gene therapy-based field. Understanding the safety of gene delivery platforms is paramount for in vivo antibody gene delivery to progress. keywords: aav; administration; antibodies; antibody; delivery; development; dmab; dna; expression; gene; human; mab; mabs; mice; mrna; pdna; plasmid; potential; studies; study; synthetic; therapy; vectors; virus; vivo cache: cord-010680-lc1onm53.txt plain text: cord-010680-lc1onm53.txt item: #68 of 449 id: cord-010812-zs51z5la author: Vaisbourd, Yulia title: The effect of patent ductus arteriosus on coronary artery blood flow in premature infants: a prospective observational pilot study date: 2020-02-20 words: 4721 flesch: 48 summary: time to accept the null hypothesis? Regional tissue oxygenation in preterm born infants in association with echocardiographically significant patent ductus arteriosus The hemodynamic effects of neonatal patent ductus arteriosus shunting on superior mesenteric artery blood flow Acute decrease of coronary flow after indomethacin delivery in newborn lambs Indomethacin impairs coronary perfusion in infants with hemodynamically significant ductus arteriosus Cyclooxygenase inhibitors in preterm infants with patent ductus arteriosus: effects on cardiac and vascular indices Coronary artery perfusion and myocardial performance after patent ductus arteriosus ligation Effects of coil closure of patent ductus arteriosus on left anterior descending coronary artery blood flow using transthoracic doppler echocardiography Effects of phototherapy on coronary blood flow in healthy neonates: a pilot study Left anterior descending coronary artery flow and its relation to age in children Towards rational management of the pat ent ductus arteriosus: the need for disease staging N-terminal pro natriuretic peptide and a patent ductus arteriosus scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants Echocardiographic evaluation of patent ductus arteriosus in preterm infants Application of NPE in the assessment of a patent ductus arteriosus Umbilical cord vitamin D, ionized calcium and myocardial oxygen demand Pulsed doppler measurement of left ventricular output as early predictor of symptomatic patent ductus arteriosus in very preterm infants Diagnosis and management of patent ductus arteriosus Influence of a patent ductus arteriosus on cardiac troponin T levels in preterm infants High serum cardiac troponin T concentrations in preterm infants with respiratory distress syndrome Effect of patent ductus arteriosus and indomethacin treatment on serum cardiac troponin T levels in preterm infants with respiratory distress syndrome High-sensitivity troponin T in preterm infants with a hemodynamically significant patent ductus arteriosus ST depression suggesting subendocardial ischemia in neonates with respiratory distress syndrome and patent ductus arteriosus Association of severe placental insufficiency and systemic venous pressure rise in the fetus with increased neonatal cardiac troponin T levels Usefulness of cardiac troponin T and echocardiography in the diagnosis of hypoxic myocardial injury of full-term neonates Decrease in coronary artery flows and higher troponin values may suggest a “steal effect,” not allowing to meet the elevated myocardial oxygen demand in infants with hsPDA. keywords: ductus; flow; group; hspda; infants; pda; study; treatment; troponin cache: cord-010812-zs51z5la.txt plain text: cord-010812-zs51z5la.txt item: #69 of 449 id: cord-010977-fwz7chzf author: Myserlis, Pavlos title: Translational Genomics in Neurocritical Care: a Review date: 2020-02-20 words: 12007 flesch: 21 summary: Given that diseases common to the neurocritical care population so rarely afford access to brain tissue for pathologic or genomic analysis antemortem, model system genomic studies offer an important adjunct for translational research. As such, many model system studies start with RNA, examining how the genome responds to perturbation through the transcriptome. keywords: animal; approach; brain; care; disease; expression; gene; genome; genomic; hemorrhage; human; injury; mechanisms; models; patients; research; risk; sequencing; stroke; studies; study; systems; tbi; translational; variants cache: cord-010977-fwz7chzf.txt plain text: cord-010977-fwz7chzf.txt item: #70 of 449 id: cord-010980-sizuef1v author: None title: ECTES Abstracts 2020 date: 2020-05-11 words: 132805 flesch: 50 summary: Investigation of coagulopathies and its relevance with mortality and transfusion rates using thromboelastography in trauma patients Introduction: Inter-hospital variation in surgical intensity for trauma admissions: a multicenter cohort study L. Moore 1 , M. P. Patton 2 , I. Farhat 2 , P. A. Tardif 2 , C. Gonthier 3 , A. Belcaid 3 , F. Lauzier 2 , A. Turgeon 2 , J. Clément 2 1 Université Laval, Social and preventive medicine, québec, Canada, 2 CHU de Québec-Université-Laval, Québec, Canada, 3 Introduction: Guidelines for trauma patients are increasingly moving away from surgical management towards less invasive procedures but there is a knowledge gap on how these recommendations are influencing practice. keywords: 0.001; abdomen; abdominal; acute; admission; adult patients; age; aim; analysis; approach; average; bleeding; blood; blunt; bone; brain; cases; cause; chest; clinical; cohort; cohort study; comments; complications; conclusions; control; data; days; death; department; diagnosis; emergency; emergency surgery; factors; findings; fixation; follow; following; fractures; general; good; grade; group; head; hip; history; hospital; hospital mortality; icu; incidence; increased; injuries; injury; injury severity; introduction; investigation; iss; laparotomy; left; level; literature; male; management; material; mean; mechanism; median; medical; methods; model; months; mortality; mortality rate; neck; need; non; number; open; operative; outcomes; p =; pain; patients c; patients introduction; pelvic; period; plate; polytrauma patients; population; postoperative; pressure; primary; procedure; progressions; range; rate; reduction; results; review; right; risk; scan; score; screw; severity; shock; stay; studies; study; study introduction; surgeons; surgery; surgery patients; survival; system; technique; test; therapy; time; tissue; total; transfusion; trauma care; trauma center; trauma patients; trauma registry; trauma surgery; trauma team; treatment; type; university; use; vascular; wound; years cache: cord-010980-sizuef1v.txt plain text: cord-010980-sizuef1v.txt item: #71 of 449 id: cord-011062-ukz4hnmy author: None title: Poster date: 2020-03-11 words: 88442 flesch: 49 summary: Greater grip strength was associated with lower % of body fat and higher % of muscle mass. Conclusion: Older adult patients hospitalized for hip fracture who had frailty, functional dependence, and social problems had significant adverse events at a general hospital in Lima, Peru. keywords: activities; activity; adults; age; aging; analysis; assessment; association; background; baseline; bmi; body; care; cognitive; cohort; community; conclusion; criteria; cross; daily; data; day; decline; differences; disability; disease; dwelling; effect; elderly; exercise; factors; falls; fat; follow; frailty; frailty index; frailty screening; frailty status; function; gait; geriatric; grip; grip strength; group; health; high; hospital; impairment; increase; individuals; intake; intervention; level; life; living; loss; low; mean; measures; methods; model; months; mortality; muscle; muscle function; muscle health; muscle mass; muscle strength; non; obesity; objectives; outcomes; p<0.001; participants; patients; people; performance; physical; population; prevalence; program; protein; quality; regression; results; risk; sample; sarcopenia; score; screening; sex; speed; sppb; studies; study; subjects; surgery; test; time; total; training; university; vs.; walking; weight; women; years cache: cord-011062-ukz4hnmy.txt plain text: cord-011062-ukz4hnmy.txt item: #72 of 449 id: cord-011325-r42hzazp author: Stowe, Julia title: Do Vaccines Trigger Neurological Diseases? Epidemiological Evaluation of Vaccination and Neurological Diseases Using Examples of Multiple Sclerosis, Guillain–Barré Syndrome and Narcolepsy date: 2019-10-01 words: 4777 flesch: 36 summary: In this article, which focusses on the evaluation of the relationship between vaccination and neurological diseases, the statistical approaches to causality assessment are first discussed and their relative merits evaluated, followed by an overview of a selection of vaccine safety studies involving neurological disease with differing conclusions; some of the included studies have shown a small elevated risk, others none, two lack evidence to draw any definitive conclusion and one provides robust evidence of causal association. Cohort studies are feasible for vaccine safety studies when data from a whole country or region can be used. keywords: association; cases; influenza; narcolepsy; risk; safety; study; vaccination; vaccine cache: cord-011325-r42hzazp.txt plain text: cord-011325-r42hzazp.txt item: #73 of 449 id: cord-011335-pamcpi8n author: Govindan, Vedavalli title: Cerebral venous volume changes and pressure autoregulation in critically ill infants date: 2020-03-10 words: 3813 flesch: 36 summary: To study the effect of ventilator-related cerebral venous volume changes on cerebral pressure autoregulation, we categorized epochs as cerebral pressure passive (coherence MAP-HbD > 0.3842) or cerebral autoregulating (coherence MAP-HbD ≤ 0.3842). Typically, cerebral pressure autoregulation maintains a relatively constant cerebral blood flow (CBF) over a range (the cerebral pressure autoregulation plateau) of cerebral perfusion pressures (CPP, the gradient between arterial blood pressure and cerebral venous pressure), thereby buffering variations in systemic arterial blood pressure [1, 3] . keywords: autoregulation; brain; cerebral; changes; infants; injury; passivity; pressure; study cache: cord-011335-pamcpi8n.txt plain text: cord-011335-pamcpi8n.txt item: #74 of 449 id: cord-011952-mm06uzxx author: Rücker, Gerta title: The statistical importance of a study for a network meta-analysis estimate date: 2020-07-16 words: 6625 flesch: 50 summary: Our concept of study importance does not start from the hat matrix, but interprets the importance of a study to a comparison as the relative reduction of the variance of the estimate when adding the study to the network. Of note, however, the importance concept allows approximate 'study weights' to be derived also for one-stage pairwise meta-analyses based on a generalized linear model, such as logistic regression, where study weights are not commonly provided. keywords: comparison; evidence; importance; meta; network; studies; study; variance cache: cord-011952-mm06uzxx.txt plain text: cord-011952-mm06uzxx.txt item: #75 of 449 id: cord-012115-hpsxi9ay author: Archie, Patrick title: Music-based interventions in palliative cancer care: a review of quantitative studies and neurobiological literature date: 2013-05-30 words: 6736 flesch: 33 summary: A study in hospitalized advanced cancer patients Anxiety disorders in advanced cancer patients Depression and anxiety disorders in palliative cancer care Role of interactive music in oncological pediatric patients undergoing painful procedures Effectiveness of music therapy for anxiety reduction in women with breast cancer in chemotherapy treatment Reducing treatment-related anxiety in cancer patients: comparison of psychological interventions Music as a therapeutic intervention for anxiety in patients receiving radiation therapy The effect of music on preoperative anxiety in day surgery A comparison of intraoperative or postoperative exposure to music-a controlled trial of the effects on postoperative pain Stress reduction and analgesia in patients exposed to calming music postoperatively: a randomized controlled trial Sedative music reduces anxiety and pain during chair rest after open-heart surgery Duocastella AC (1999) Effect of music on children with cancer The quality of life of cancer patients: a review of the literature General Population and cancer patient norms for the Functional Assessment of Cancer Therapy-General (FACT-G) Health-related quality of life in longterm head and neck cancer survivors: a comparison with general population norms ed) Handbook of pain and palliative care: biobehavioral approaches for the life course Defining the content domain of quality of life for cancer patients with pain keywords: anxiety; cancer; cancer patients; care; depression; interventions; life; mood; music; pain; palliative; patients; studies; therapy cache: cord-012115-hpsxi9ay.txt plain text: cord-012115-hpsxi9ay.txt item: #76 of 449 id: cord-012518-ncrdwtdg author: None title: Abstractband DOG 2020 date: 2020-08-24 words: 32667 flesch: 52 summary: In 1852 he founded famous private eye clinic in Berlin, where he treated many eye patients and educated many prominent ophthalmologists. In I group patients were examined before the first time and after 3 months of SCL wear. keywords: a. 1; acuity; age; analysis; anti; auf; baseline; bei; cases; cells; changes; cnv; conclusions; control; corneal; data; der; des; diabetic; die; disease; eine; expression; eyes; following; für; germany; glaucoma; group; gruppe; implant; incidence; iod; iop; length; lens; light; mean; membrane; methods; mit; mmhg; months; n =; nach; non; oct; optic; oxygen; patienten; patients; primary; purpose; results; sich; stage; studies; study; surgery; survival; term; therapy; thickness; time; treatment; und; uveitis; von; war; werden; years cache: cord-012518-ncrdwtdg.txt plain text: cord-012518-ncrdwtdg.txt item: #77 of 449 id: cord-012778-yr8zuvw9 author: Zhang, Lei title: Quantitative efficacy of three antipsychotic drugs for schizophrenia based on a real-world study in China date: 2019-08-06 words: 5060 flesch: 41 summary: All of these evaluation results indicated good predictability of the final models. Typical drug efficacy values According to the final model parameters, we examined the efficacy values of the three antipsychotics at 26, 52, 78, 104, 130, and 156 weeks and simulated the typical efficacy-time curves (Fig. 3a) . The CATIE (Clinical Antipsychotic Trials of Intervention Effectiveness) schizophrenia study conducted by the National Institute of Mental Health (NIMH) is the most wellknown comparative study of the effectiveness of antipsychotic drugs [10, 11] . keywords: antipsychotic; efficacy; model; olanzapine; patients; risperidone; schizophrenia; score; study cache: cord-012778-yr8zuvw9.txt plain text: cord-012778-yr8zuvw9.txt item: #78 of 449 id: cord-012980-oaie2i8m author: FRIEDMAN, MARVIN A. title: A Lifetime Oncogenicity Study in Rats with Acrylamide date: 1995-08-17 words: 7433 flesch: 45 summary: The Fischer 344 rat developed a very high incidence of Leydig cell tumors (greater than 90% incidence in control rats at the end of 2 years) resulting in dramatic hormonal imbalances in aging rats carrying these tumors (Turek and Desjardins, 1979 ). The study was planned to have sufficient statistical power for detection of a 5% increase in tumor incidence in comparison to an expected 1.3% control background incidence (Solleveld el al, 1984) for the most infrequently noted male tumor type, scrotal mesotheliomas, reported in the Johnson el al. keywords: acrylamide; animals; cell; control; dose; female; groups; incidence; rats; study; tumors; water cache: cord-012980-oaie2i8m.txt plain text: cord-012980-oaie2i8m.txt item: #79 of 449 id: cord-013138-4e9vo0xr author: Lang-Illievich, Kordula title: The Effect of Low-Level Light Therapy on Capsaicin-Induced Peripheral and Central Sensitization in Healthy Volunteers: A Double-Blinded, Randomized, Sham-Controlled Trial date: 2020-10-10 words: 3990 flesch: 42 summary: To provide an answer to these questions, we use a human pain model developed to mimic different aspects of clinical pain and to study pain mechanisms in order to examine whether peripheral or central mechanisms contribute to the analgetic effect of LLLT. Indications for LLLT are the improvement of wound healing and tissue regeneration, scarring, and perfusion, as well as pain therapy. keywords: capsaicin; data; effect; level; light; lllt; pain; sensitization; study; therapy cache: cord-013138-4e9vo0xr.txt plain text: cord-013138-4e9vo0xr.txt item: #80 of 449 id: cord-013830-qfvceu65 author: Ang, Juan Lyn title: A systematic review of real-world evidence of the management of macular oedema secondary to branch retinal vein occlusion date: 2020-04-20 words: 9892 flesch: 40 summary: Natural history of branch retinal vein occlusion: an evidence-based systematic review Argon laser photocoagulation for macular edema in branch vein occlusion Changes of aqueous vascular endothelial growth factor and interleukin-6 after intravitreal triamcinolone for branch retinal vein occlusion A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6 Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion twelve-month study results The Royal College of Ophthalmologists. The Royal College of Ophthalmologists Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study Ranibizumab for macular edema due to retinal vein occlusions: long-term follow-up in the HORIZON trial Long-term outcomes in patients with retinal vein occlusion treated with ranibizumab: the RETAIN study Individualized stabilization criteria-driven ranibizumab versus laser in branch keywords: arms; bevacizumab; branch; edema; intravitreal; occlusion; outcomes; patients; secondary; studies; study; treatment; vein; world cache: cord-013830-qfvceu65.txt plain text: cord-013830-qfvceu65.txt item: #81 of 449 id: cord-014462-11ggaqf1 author: None title: Abstracts of the Papers Presented in the XIX National Conference of Indian Virological Society, “Recent Trends in Viral Disease Problems and Management”, on 18–20 March, 2010, at S.V. University, Tirupati, Andhra Pradesh date: 2011-04-21 words: 35463 flesch: 47 summary: The following virus isolates have been used in the analysis: GTPV-Uttarkashi, P60, vaccine virus; GTPV Mukteswar, P10, Challenge virus; GTPV (Akola), GTPV Bareilly/00, GTPV Ladakh/01 and GTPV Sambalpur/82, field isolates and SPPV Srinagar, P40; SPPV Ranipet, P50; SPPV-RF, P50, vaccine viruses and SPPV Makdhoom/07, SPPV CIRG/08, SPPV Pune/08, SPPV Bareilly, SPPV 183/03 and SPPV 125/02, field isolates. Present paper discusses about virus disease of quarantine importance affecting ornamental and fruit plants such as Chrysanthimum, Dahlia, Dianthus, Rosabengalensis, Cattleya, Cymbidium, Dendrobium, Lilium, Citrus, Vitis etc. keywords: acid; analysis; animals; antibodies; antigen; assay; cases; cells; cloned; control; crop; curl; dengue; detection; development; disease; dna; elisa; expression; field; food; gene; host; india; infection; isolates; leaf; management; methods; molecular; mosaic; mosaic virus; nucleotide; pathogens; patients; pcr; plant; positive; present; primers; production; protein; region; resistance; response; results; rna; samples; sequence; specific; study; symptoms; time; tomato; total; vaccine; vector; viral; virus; virus infection; viruses; world; yellow cache: cord-014462-11ggaqf1.txt plain text: cord-014462-11ggaqf1.txt item: #82 of 449 id: cord-014464-m5n250r2 author: Sole-Violan, J title: Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date: 2013-03-19 words: 99097 flesch: 51 summary: The application of the endotoxin activity assay was useful for bedside monitoring of endotoxemia in ICU patients. The aim of this study is to describe the clinical and epidemiological profi le of ICU patients receiving tigecycline (TGC) and to evaluate the potential benefi ts of TGC higher doses. keywords: acute; admission; adult patients; age; aim; analysis; blood; brain; cardiac; care; care patients; cases; clinical; conclusion; confi; control; criteria; critical; data; days; defi; diff; dose; early; ect; eff; emergency; erence; erent; failure; fi rst; figure; function; group; guidelines; high; hospital; hospital mortality; hours; icu admission; icu mortality; icu patients; icu stay; icus; identifi; increase; infl; injury; intensive; introduction; length; levels; low; lung; management; mean; median; medical; methods; methods patients; minutes; months; mortality; n =; number; nurses; organ; outcome; p =; patients; period; post; pressure; protocol; rate; renal; response; results; risk; rst; score; sepsis; septic; severity; shock; shock patients; signifi; stay; studies; study; surgery; surgery patients; surgical; test; therapy; time; total; treatment; uid; use; ventilation; volume; years cache: cord-014464-m5n250r2.txt plain text: cord-014464-m5n250r2.txt item: #83 of 449 id: cord-014516-r59usk02 author: None title: Research Communications of the 24th ECVIM‐CA Congress date: 2015-01-10 words: 55086 flesch: 49 summary: Method specificity was confirmed by the absence of matrix effect in six serum specimen obtained from clinical dogs. Stage C dogs had lower SRs (p = 0.0005), higher SRe (p = 0.0029) and SRa (p = 0.0004) than other dogs. keywords: age; aim; analysis; animal; associated; blood; body; breed; canine; cardiac; cases; cats; cell; chronic; common; concentrations; conflicts; control; data; days; diagnosis; disease; dogs; fcv; fecal; feline; following; function; group; healthy; heart; human; interest; loss; ltd; mean; measurements; median; months; non; normal; patients; pcr; positive; prevalence; range; rate; reference; renal; results; risk; samples; serum; severity; signs; studies; study; test; time; total; treatment; values; veterinary; weeks; weight; years cache: cord-014516-r59usk02.txt plain text: cord-014516-r59usk02.txt item: #84 of 449 id: cord-014527-nvzfpntu author: None title: Research Communications of the 25th ECVIM‐CA Congress date: 2015-11-09 words: 89290 flesch: 49 summary: Dogs in the prolonged OS group were more likely to be anaemic on presentation (PCV<37%, P = 0.041), experienced a greater FRD (P = 0.012) and were more likely to be treated with a rescue protocol (P = 0.036) than other dogs. Dogs that did not respond to treatment had significantly higher S100A12 levels than dogs with partial (P = 0.005) or complete (P = 0.003) remission, but response to treatment was associated with disease classification (P = 0.020). keywords: 0.001; age; aim; analysis; animals; bcs; blood; body; breed dogs; breeds; canine; cardiac; cases; cats; cells; chronic; clinical; concentrations; control; control dogs; correlation; crp; data; days; diagnosis; difference; disclosures; disease; dogs; echocardiography; examination; feline; function; group; heart; humans; infection; levels; mean; measurements; median; method; mmhg; months; n =; non; outcome; owners; p =; patients; pcr; population; positive; presence; present; prevalence; range; rate; renal; report; results; right; samples; serum; signs; small; specific; studies; study; survival; systolic; test; time; total; treatment; use; values; veterinary; weight; years cache: cord-014527-nvzfpntu.txt plain text: cord-014527-nvzfpntu.txt item: #85 of 449 id: cord-014533-6qfecv5h author: Velasquez, T. title: ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016 date: 2016-09-29 words: 88447 flesch: 46 summary: key: cord-014533-6qfecv5h authors: Velasquez, T.; Mackey, G.; Lusk, J.; Kyle, U. G.; Fontenot, T.; Marshall, P.; Shekerdemian, L. S.; Coss-Bu, J. A.; Nishigaki, A.; Yatabe, T.; Tamura, T.; Yamashita, K.; Yokoyama, M.; Ruiz-Rodriguez, J. C.; Encina, B.; Belmonte, R.; Troncoso, I.; Tormos, P.; Riveiro, M.; Baena, J.; Sanchez, A.; Bañeras, J.; Cordón, J.; Duran, N.; Ruiz, A.; Caballero, J.; Nuvials, X.; Riera, J.; Serra, J.; Rutten, A. M. F.; van Ieperen, S. N. M.; Der Kinderen, E. P. H. M.; Van Logten, T.; Kovacikova, L.; Skrak, P.; Zahorec, M.; Kyle, U. G.; Akcan-Arikan, A.; Silva, J. C.; Mackey, G.; Lusk, J.; Goldsworthy, M.; Shekerdemian, L. S.; Coss-Bu, J. A.; Wood, D.; Harrison, D.; Parslow, R.; Davis, P.; Pappachan, J.; Goodwin, S.; Ramnarayan, P.; Chernyshuk, S.; Yemets, H.; Zhovnir, V.; Pulitano’, S. M.; De Rosa, S.; Mancino, A.; Villa, G.; Tosi, F.; Franchi, P.; Conti, G.; Patel, B.; Khine, H.; Shah, A.; Sung, D.; Singer, L.; Haghbin, S.; Inaloo, S.; Serati, Z.; Idei, M.; Nomura, T.; Yamamoto, N.; Sakai, Y.; Yoshida, T.; Matsuda, Y.; Yamaguchi, Y.; Takaki, S.; Yamaguchi, O.; Goto, T.; Longani, N.; Medar, S.; Abdel-Aal, I. R.; El Adawy, A. S.; Mohammed, H. M. E. H.; Mohamed, A. N.; Parry, S. M.; Knight, L. D.; Denehy, L.; De Morton, N.; Baldwin, C. E.; Sani, D.; Kayambu, G.; da Silva, V. Z. M.; Phongpagdi, P.; Puthucheary, Z. A.; Granger, C. L.; Rydingsward, J. E.; Horkan, C. M.; Christopher, K. B.; McWilliams, D.; Jones, C.; Reeves, E.; Atkins, G.; Snelson, C.; Aitken, L. M.; Rattray, J.; Kenardy, J.; Hull, A. M.; Ullman, A.; Le Brocque, R.; Mitchell, M.; Davis, C.; Macfarlane, B.; Azevedo, J. C.; Rocha, L. L.; De Freitas, F. F. M.; Cavalheiro, A. M.; Lucinio, N. M.; Lobato, M. S.; Ebeling, G.; Kraegpoeth, A.; Laerkner, E.; De Brito-Ashurst, I.; White, C.; Gregory, S.; Forni, L. G.; Flowers, E.; Curtis, A.; Wood, C. A.; Siu, K.; Venkatesan, K.; Muhammad, J. B. H.; Ng, L.; Seet, E.; Baptista, N.; Escoval, A.; Tomas, E.; Agrawal, R.; Mathew, R.; Varma, A.; Dima, E.; Charitidou, E.; Perivolioti, E.; Pratikaki, M.; Vrettou, C.; Giannopoulos, A.; Zakynthinos, S.; Routsi, C.; Atchade, E.; Houzé, S.; Jean-Baptiste, S.; Thabut, G.; Genève, C.; Tanaka, S.; Lortat-Jacob, B.; Augustin, P.; Desmard, M.; Montravers, P.; de Molina, F. J. González; Barbadillo, S.; Alejandro, R.; Álvarez-Lerma, F.; Vallés, J.; Catalán, R. M.; Palencia, E.; Jareño, A.; Granada, R. M.; Ignacio, M. L.; Cui, N.; Liu, D.; Wang, H.; Su, L.; Qiu, H.; Li, R.; Jaffal, K.; Rouzé, A.; Poissy, J.; Sendid, B.; Nseir, S.; Paramythiotou, E.; Rizos, M.; Frantzeskaki, F.; Antoniadou, A.; Vourli, S.; Zerva, L.; Armaganidis, A.; Riera, J.; Gottlieb, J.; Greer, M.; Wiesner, O.; Martínez, M.; Acuña, M.; Rello, J.; Welte, T.; Atchade, E.; Mignot, T.; Houzé, S.; Jean-Baptiste, S.; Thabut, G.; Lortat-Jacob, B.; Tanaka, S.; Augustin, P.; Desmard, M.; Montravers, P.; Soussi, S.; Dudoignon, E.; Ferry, A.; Chaussard, M.; Benyamina, M.; Alanio, A.; Touratier, S.; Chaouat, M.; Lafaurie, M.; Mimoun, M.; Mebazaa, A.; Legrand, M.; Sheils, M. A.; Patel, C.; Mohankumar, L.; Akhtar, N.; Noriega, S. K. Pacheco; Aldana, N. Navarrete; León, J. L. Ávila; Baquero, J. Durand; Bernal, F. Fernández; Ahmadnia, E.; Hadley, J. S.; Millar, M.; Hall, D.; Hewitt, H.; Yasuda, H.; Sanui, M.; Komuro, T.; Kawano, S.; Andoh, K.; Yamamoto, H.; Noda, E.; Hatakeyama, J.; Saitou, N.; Okamoto, H.; Kobayashi, A.; Takei, T.; Matsukubo, S.; Rotzel, H. B.; Lázaro, A. Serrano; Prada, D. Aguillón; Gimillo, M. Rodriguez; Barinas, O. Diaz; Cortes, M. L. Blasco; Franco, J. Ferreres; Roca, J. M. Segura; Carratalá, A.; Gonçalves, B.; Turon, R.; Mendes, A.; Miranda, F.; Mata, P. J.; Cavalcanti, D.; Melo, N.; Lacerda, P.; Kurtz, P.; Righy, C.; Rosario, L. E. de la Cruz; Lesmes, S. P. Gómez; Romero, J. C. García; Herrera, A. N. García; Pertuz, E. D. Díaz; Sánchez, M. J. Gómez; Sanz, E. Regidor; Hualde, J. Barado; Hernández, A. Ansotegui; Irazabal, J. M. Guergué; Spatenkova, V.; Bradac, O.; Suchomel, P.; Urli, T.; Lazzeri, E. Heusch; Aspide, R.; Zanello, M.; Perez-Borrero, L.; Garcia-Alvarez, J. M.; Arias-Verdu, M. D.; Aguilar-Alonso, E.; Rivera-Fernandez, R.; Mora-Ordoñez, J.; De La Fuente-Martos, C.; Castillo-Lorente, E.; Guerrero-Lopez, F.; Lesmes, S. P. Gómez; Rosario, L. E. De la Cruz; Pertuz, E. D. Díaz; Hernández, A. Ansotegui; Romero, J. C. García; Sánchez, M. J. Gómez; Herrera, A. N. García; Ramírez, J. Roldán; Sanz, E. Regidor; Hualde, J. Barado; León, J. P. Tirapu; Navarro-Guillamón, L.; Cordovilla-Guardia, S.; Iglesias-Santiago, A.; Guerrero-López, F.; Fernández-Mondéjar, E.; Vidal, A.; Perez, M.; Juez, A.; Arias, N.; Colino, L.; Perez, J. L.; Pérez, H.; Calpe, P.; Alcala, M. A.; Robaglia, D.; Perez, C.; Lan, S. K.; Cunha, M. M.; Moreira, T.; Santos, F.; Lafuente, E.; Fernandes, M. J.; Silva, J. G.; Rosario, L. E. de la Cruz; Lesmes, S. P. Gómez; Herrera, A. N. García; Romero, J. C. García; Pertuz, E. D. Díaz; Sánchez, M. J. Gómez; Sanz, E. Regidor; Echeverría, J. G. Armando; Hernández, A. Ansotegui; Hualde, J. Barado; Podlepich, V.; Sokolova, E.; Alexandrova, E.; Lapteva, K.; Kurtz, P.; Shuinotsuka, C.; Rabello, L.; Vianna, G.; Reis, A.; Cairus, C.; Salluh, J.; Bozza, F.; Torres, J. C. Barrios; Araujo, N. J. Fernández; García-Olivares, P.; Keough, E.; Dalorzo, M.; Tang, L. K.; De Sousa, I.; Díaz, M.; Marcos-Zambrano, L. J.; Guerrero, J. E.; Gomez, S. E. Zamora; Lopez, G. D. Hernandez; Cuellar, A. I. Vazquez; Nieto, O. R. Perez; Gonzalez, J. A. Castanon; Bhasin, D.; Rai, S.; Singh, H.; Gupta, O.; Bhattal, M. K.; Sampley, S.; Sekhri, K.; Nandha, R.; Aliaga, F. A.; Olivares, F.; Appiani, F.; Farias, P.; Alberto, F.; Hernández, A.; Pons, S.; Sonneville, R.; Bouadma, L.; Neuville, M.; Mariotte, E.; Radjou, A.; Lebut, J.; Chemam, S.; Voiriot, G.; Dilly, M. P.; Mourvillier, B.; Dorent, R.; Nataf, P.; Wolff, M.; Timsit, J. F.; Ediboglu, O.; Ataman, S.; Ozkarakas, H.; Kirakli, C.; Vakalos, A.; Avramidis, V.; Obukhova, O.; Kurmukov, I. A.; Kashiya, S.; Golovnya, E.; Baikova, V. N.; Ageeva, T.; Haritydi, T.; Kulaga, E. V.; Rios-Toro, J. J.; Perez-Borrero, L.; Aguilar-Alonso, E.; Arias-Verdu, M. D.; Garcia-Alvarez, J. M.; Lopez-Caler, C.; De La Fuente-Martos, C.; Rodriguez-Fernandez, S.; Sanchez-Orézzoli, M. Gomez; Martin-Gallardo, F.; Nikhilesh, J.; Joshi, V.; Villarreal, E.; Ruiz, J.; Gordon, M.; Quinza, A.; Gimenez, J.; Piñol, M.; Castellanos, A.; Ramirez, P.; Jeon, Y. D.; Jeong, W. Y.; Kim, M. H.; Jeong, I. Y.; Ahn, M. Y.; Ahn, J. Y.; Han, S. H.; Choi, J. Y.; Song, Y. G.; Kim, J. M.; Ku, N. S.; Shah, H.; Kellner, F.; Rezai, F.; Mistry, N.; Yodice, P.; Ovnanian, V.; Fless, K.; Handler, E.; Alejos, R. Martínez; Romeu, J. D. Martí; Antón, D. González; Quinart, A.; Martí, A. Torres; Llaurado-Serra, M.; Lobo-Civico, A.; Ventura-Rosado, A.; Piñol-Tena, A.; Pi-Guerrero, M.; Paños-Espinosa, C.; Peralvo-Bernat, M.; Marine-Vidal, J.; Gonzalez-Engroba, R.; Montesinos-Cerro, N.; Treso-Geira, M.; Valeiras-Valero, A.; Martinez-Reyes, L.; Sandiumenge, A.; Jimenez-Herrera, M. F.; Helyar, S.; Riozzi, P.; Noon, A.; Hallows, G.; Cotton, H.; Keep, J.; Hopkins, P. A.; Taggu, A.; Renuka, S.; Sampath, S.; Rood, P. J. T.; Frenzel, T.; Verhage, R.; Bonn, M.; Pickkers, P.; van der Hoeven, J. G.; van den Boogaard, M.; Corradi, F.; Melnyk, L.; Moggia, F.; Pienovi, R.; Adriano, G.; Brusasco, C.; Mariotti, L.; Lattuada, M.; Bloomer, M. J.; Coombs, M.; Ranse, K.; Endacott, R.; Maertens, B.; Blot, K.; Blot, S.; Amerongen, M. P. van Nieuw; van der Heiden, E. S.; Twisk, J. W. R.; Girbes, A. R. J.; Spijkstra, J. J.; Riozzi, P.; Helyar, S.; Cotton, H.; Hallows, G.; Noon, A.; Bell, C.; Peters, K.; Feehan, A.; Keep, J.; Hopkins, P. A.; Churchill, K.; Hawkins, K.; Brook, R.; Paver, N.; Endacott, R.; Maistry, N.; van Wijk, A.; Rouw, N.; van Galen, T.; Evelein-Brugman, S.; Taggu, A.; Krishna, B.; Sampath, S.; Putzu, A.; Fang, M.; Berto, M. Boscolo; Belletti, A.; Cassina, T.; Cabrini, L.; Mistry, M.; Alhamdi, Y.; Welters, I.; Abrams, S. T.; Toh, C. H.; Han, H. S.; Gil, E. M.; Lee, D. S.; Park, C. M.; Winder-Rhodes, S.; Lotay, R.; Doyle, J.; Ke, M. W.; Huang, W. C.; Chiang, C. H.; Hung, W. T.; Cheng, C. C.; Lin, K. C.; Lin, S. C.; Chiou, K. R.; Wann, S. R.; Shu, C. W.; Kang, P. L.; Mar, G. Y.; Liu, C. P.; Dubó, S.; Aquevedo, A.; Jibaja, M.; Berrutti, D.; Labra, C.; Lagos, R.; García, M. F.; Ramirez, V.; Tobar, M.; Picoita, F.; Peláez, C.; Carpio, D.; Alegría, L.; Hidalgo, C.; Godoy, K.; Bakker, J.; Hernández, G.; Sadamoto, Y.; Katabami, K.; Wada, T.; Ono, Y.; Maekawa, K.; Hayakawa, M.; Sawamura, A.; Gando, S.; Marin-Mateos, H.; Perez-Vela, J. L.; Garcia-Gigorro, R.; Peiretti, M. A. Corres; Lopez-Gude, M. J.; Chacon-Alves, S.; Renes-Carreño, E.; Montejo-González, J. C.; Parlevliet, K. L.; Touw, H. R. W.; Beerepoot, M.; Boer, C.; Elbers, P. W. G.; Tuinman, P. R.; Abdelmonem, S. A.; Helmy, T. A.; El Sayed, I.; Ghazal, S.; Akhlagh, S. H.; Masjedi, M.; Hozhabri, K.; Kamali, E.; Zýková, I.; Paldusová, B.; Sedlák, P.; Morman, D.; Youn, A. M.; Ohta, Y.; Sakuma, M.; Bates, D.; Morimoto, T.; Su, P. L.; Chang, W. Y.; Lin, W. C.; Chen, C. W.; Facchin, F.; Zarantonello, F.; Panciera, G.; De Cassai, A.; Venrdramin, A.; Ballin, A.; Tonetti, T.; Persona, P.; Ori, C.; Del Sorbo, L.; Rossi, S.; Vergani, G.; Cressoni, M.; Chiumello, D.; Chiurazzi, C.; Brioni, M.; Algieri, I.; Tonetti, T.; Guanziroli, M.; Colombo, A.; Tomic, I.; Colombo, A.; Crimella, F.; Carlesso, E.; Gasparovic, V.; Gattinoni, L.; Neto, A. Serpa; Schmidt, M.; Pham, T.; Combes, A.; de Abreu, M. Gama; Pelosi, P.; Schultz, M. J.; Katira, B. H.; Engelberts, D.; Giesinger, R. E.; Ackerley, C.; Yoshida, T.; Zabini, D.; Otulakowski, G.; Post, M.; Kuebler, W. M.; McNamara, P. J.; Kavanagh, B. P.; Pirracchio, R.; Rigon, M. Resche; Carone, M.; Chevret, S.; Annane, D.; Eladawy, S.; El-Hamamsy, M.; Bazan, N.; Elgendy, M.; De Pascale, G.; Vallecoccia, M. S.; Cutuli, S. L.; Di Gravio, V.; Pennisi, M. A.; Conti, G.; Antonelli, M.; Andreis, D. T.; Khaliq, W.; Singer, M.; Hartmann, J.; Harm, S.; Carmona, S. Alcantara; Almudevar, P. Matia; Abellán, A. Naharro; Ramos, J. Veganzones; Pérez, L. Pérez; Valbuena, B. Lobo; Sanz, N. Martínez; Simón, I. Fernández; Arrigo, M.; Feliot, E.; Deye, N.; Cariou, A.; Guidet, B.; Jaber, S.; Leone, M.; Resche-Rigon, M.; Baron, A. Vieillard; Legrand, M.; Gayat, E.; Mebazaa, A.; Balik, M.; Kolnikova, I.; Maly, M.; Waldauf, P.; Tavazzi, G.; Kristof, J.; Herpain, A.; Su, F.; Post, E.; Taccone, F.; Vincent, J. L.; Creteur, J.; Lee, C.; Hatib, F.; Jian, Z.; Buddi, S.; Cannesson, M.; Fileković, S.; Turel, M.; Knafelj, R.; Gorjup, V.; Stanić, R.; Gradišek, P.; Cerović, O.; Mirković, T.; Noč, M.; Tirkkonen, J.; Hellevuo, H.; Olkkola, K. T.; Hoppu, S.; Lin, K. C.; Hung, W. T.; Chiang, C. C.; Huang, W. C.; Juan, W. C.; Lin, S. C.; Cheng, C. C.; Lin, P. H.; Fong, K. Y.; Hou, D. S.; Kang, P. L.; Wann, S. R.; Chen, Y. S.; Mar, G. Y.; Liu, C. P.; Paul, M.; Bougouin, W.; Geri, G.; Dumas, F.; Champigneulle, B.; Legriel, S.; Charpentier, J.; Mira, J. P.; Sandroni, C.; Cariou, A.; Zimmerman, J.; Sullivan, E.; Noursadeghi, M.; Fox, B.; Sampson, D.; McHugh, L.; Yager, T.; Cermelli, S.; Seldon, T.; Bhide, S.; Brandon, R. A.; Brandon, R. B.; Zwaag, J.; Beunders, R.; Pickkers, P.; Kox, M.; Gul, F.; Arslantas, M. K.; Genc, D.; Zibandah, N.; Topcu, L.; Akkoc, T.; Cinel, I.; Greco, E.; Lauretta, M. P.; Andreis, D. T.; Singer, M.; Garcia, I. Palacios; Cordero, M.; Martin, A. Diaz; Pallás, T. Aldabó; Montero, J. Garnacho; Rey, J. Revuelto; Malo, L. Roman; Montoya, A. A. Tanaka; Martinez, A. D. C. Amador; Ayala, L. Y. Delgado; Zepeda, E. Monares; Granillo, J. Franco; Sanchez, J. Aguirre; Alejo, G. Camarena; Cabrera, A. Rugerio; Montenegro, A. Pedraza; Pham, T.; Beduneau, G.; Schortgen, F.; Piquilloud, L.; Zogheib, E.; Jonas, M.; Grelon, F.; Runge, I.; Terzi, N.; Grangé, S.; Barberet, G.; Guitard, P. G.; Frat, J. P.; Constan, A.; Chrétien, J. M.; Mancebo, J.; Mercat, A.; Richard, J. C. M.; Brochard, L.; Soilemezi, E.; Koco, E.; Savvidou, S.; Nouris, C.; Matamis, D.; Di Mussi, R.; Spadaro, S.; Volta, C. A.; Mariani, M.; Colaprico, A.; Antonio, C.; Bruno, F.; Grasso, S.; Rodriguez, A.; Martín-Loeches, I.; Díaz, E.; Masclans, J. R.; Gordo, F.; Solé-Violán, J.; Bodí, M.; Avilés-Jurado, F. X.; Trefler, S.; Magret, M.; Reyes, L. F.; Marín-Corral, J.; Yebenes, J. C.; Esteban, A.; Anzueto, A.; Aliberti, S.; Restrepo, M. I.; Larsson, J. Skytte; Redfors, B.; Ricksten, S. E.; Haines, R.; Powell-Tuck, J.; Leonard, H.; Ostermann, M.; Berthelsen, R. E.; Itenov, T. S.; Perner, A.; Jensen, J. U.; Ibsen, M.; Jensen, A. E. K.; Bestle, M. H.; Bucknall, T.; Dixon, J.; Boa, F.; MacPhee, I.; Philips, B. J.; Doyle, J.; Saadat, F.; Samuels, T.; Huddart, S.; McCormick, B.; DeBrunnar, R.; Preece, J.; Swart, M.; Peden, C.; Richardson, S.; Forni, L.; Kalfon, P.; Baumstarck, K.; Estagnasie, P.; Geantot, M. A.; Berric, A.; Simon, G.; Floccard, B.; Signouret, T.; Boucekine, M.; Fromentin, M.; Nyunga, M.; Sossou, A.; Venot, M.; Robert, R.; Follin, A.; Renault, A.; Garrouste, M.; Collange, O.; Levrat, Q.; Villard, I.; Thévenin, D.; Pottecher, J.; Patrigeon, R. G.; Revel, N.; Vigne, C.; Mimoz, O.; Auquier, P.; Pawar, S.; Jacques, T.; Deshpande, K.; Pusapati, R.; Wood, B.; Pulham, R. A.; Wray, J.; Brown, K.; Pierce, C.; Nadel, S.; Ramnarayan, P.; Azevedo, J. R.; Montenegro, W. S.; Rodrigues, D. P.; Sousa, S. C.; Araujo, V. F.; Leitao, A. L.; Prazeres, P. H.; Mendonca, A. V.; Paula, M. P.; Das Neves, A.; Loudet, C. I.; Busico, M.; Vazquez, D.; Villalba, D.; Lischinsky, A.; Veronesi, M.; Emmerich, M.; Descotte, E.; Juliarena, A.; Bisso, M. Carboni; Grando, M.; Tapia, A.; Camargo, M.; Ulla, D. Villani; Corzo, L.; dos Santos, H. Placido; Ramos, A.; Doglia, J. A.; Estenssoro, E.; Carbonara, M.; Magnoni, S.; Donald, C. L. Mac; Shimony, J. S.; Conte, V.; Triulzi, F.; Stretti, F.; Macrì, M.; Snyder, A. Z.; Stocchetti, N.; Brody, D. L.; Podlepich, V.; Shimanskiy, V.; Savin, I.; Lapteva, K.; Chumaev, A.; Tjepkema-Cloostermans, M. C.; Hofmeijer, J.; Beishuizen, A.; Hom, H.; Blans, M. J.; van Putten, M. J. A. M.; Longhi, L.; Frigeni, B.; Curinga, M.; Mingone, D.; Beretta, S.; Patruno, A.; Gandini, L.; Vargiolu, A.; Ferri, F.; Ceriani, R.; Rottoli, M. R.; Lorini, L.; Citerio, G.; Pifferi, S.; Battistini, M.; Cordolcini, V.; Agarossi, A.; Di Rosso, R.; Ortolano, F.; Stocchetti, N.; Lourido, C. Mora; Cabrera, J. L. Santana; Santana, J. D. Martín; Alzola, L. Melián; del Rosario, C. García; Pérez, H. Rodríguez; Torrent, R. Lorenzo; Eslami, S.; Dalhuisen, A.; Fiks, T.; Schultz, M. J.; Hanna, A. Abu; Spronk, P. E.; Wood, M.; Maslove, D.; Muscedere, J.; Scott, S. H.; Saha, T.; Hamilton, A.; Petsikas, D.; Payne, D.; Boyd, J. G.; Puthucheary, Z. A.; McNelly, A. S.; Rawal, J.; Connolly, B.; McPhail, M. J.; Sidhu, P.; Rowlerson, A.; Moxham, J.; Harridge, S. D.; Hart, N.; Montgomery, H. E.; Jovaisa, T.; Thomas, B.; Gupta, D.; Wijayatilake, D. S.; Shum, H. P.; King, H. S.; Chan, K. C.; Tang, K. B.; Yan, W. W.; Arias, C. Castro; Latorre, J.; De La Rica, A. Suárez; Garrido, E. Maseda; Feijoo, A. Montero; Gancedo, C. Hernández; Tofiño, A. López; Rodríguez, F. Gilsanz; Gemmell, L. K.; Campbell, R.; Doherty, P.; MacKay, A.; Singh, N.; Vitaller, S.; Nagib, H.; Prieto, J.; Del Arco, A.; Zayas, B.; Gomez, C.; Tirumala, S.; Pasha, S. A.; Kumari, B. K.; Martinez-Lopez, P.; Puerto-Morlán, A.; Nuevo-Ortega, P.; Pujol, L. Martinez; Dolset, R. Algarte; González, B. Sánchez; Riera, S. Quintana; Álvarez, J. Trenado; Quintana, S.; Martínez, L.; Algarte, R.; Sánchez, B.; Trenado, J.; Tomas, E.; Brock, N.; Viegas, E.; Filipe, E.; Cottle, D.; Traynor, T.; Martínez, M. V. Trasmonte; Márquez, M. Pérez; Gómez, L. Colino; Martínez, N. Arias; Muñoz, J. M. Milicua; Bellver, B. Quesada; Varea, M. Muñoz; Llorente, M. Á. Alcalá; Calvo, C. Pérez; Hillier, S. D.; Faulds, M. C.; Hendra, H.; Lawrence, N.; Maekawa, K.; Hayakawa, M.; Ono, Y.; Kodate, A.; Sadamoto, Y.; Tominaga, N.; Mizugaki, A.; Murakami, H.; Yoshida, T.; Katabami, K.; Wada, T.; Sawamura, A.; Gando, S.; Silva, S.; Kerhuel, L.; Malagurski, B.; Citerio, G.; Chabanne, R.; Laureys, S.; Puybasset, L.; Nobile, L.; Pognuz, E. R.; Rossetti, A. O.; Verginella, F.; Gaspard, N.; Creteur, J.; Ben-Hamouda, N.; Oddo, M.; Taccone, F. S.; Ono, Y.; Hayakawa, M.; Iijima, H.; Maekawa, K.; Kodate, A.; Sadamoto, Y.; Mizugaki, A.; Murakami, H.; Katabami, K.; Wada, T.; Sawamura, A.; Gando, S.; Kodate, A.; Katabami, K.; Wada, T.; Ono, Y.; Maekawa, K.; Hayakawa, M.; Sawamura, A.; Gando, S.; Andersen, L. W.; Raymond, T.; Berg, R.; Nadkarni, V.; Grossestreuer, A.; Kurth, T.; Donnino, M.; Krüger, A.; Ostadal, P.; Janotka, M.; Vondrakova, D.; Kongpolprom, N.; Cholkraisuwat, J.; Pekkarinen, P. T.; Ristagno, G.; Masson, S.; Latini, R.; Bendel, S.; Ala-Kokko, T.; Varpula, T.; Vaahersalo, J.; Hoppu, S.; Tiainen, M.; Mion, M. M.; Plebani, M.; Pettilä, V.; Skrifvars, M.B.; Son, Y.; Kim, K. S.; Suh, G. J.; Kwon, W. Y.; Ko, J. I.; Park, M. J.; Cavicchi, F. Zama; Iesu, E.; Nobile, L.; Vincent, J. L.; Creteur, J.; Taccone, F. S.; Tanaka, H.; Otani, N.; Ode, S.; Ishimatsu, S.; Martínez, L.; Algarte, R.; Sánchez, B.; Romero, I.; Martínez, F.; Quintana, S.; Trenado, J.; Vondrakova, D.; Ostadal, P.; Kruger, A.; Janotka, M.; Malek, F.; Neuzil, P.; Yeh, Y. C.; Chen, Y. S.; Wang, C. H.; Huang, C. H.; Chao, A.; Lee, C. T.; Lai, C. H.; Chan, W. S.; Cheng, Y. J.; Sun, W. Z.; Kaese, S.; Horstmann, C.; Lebiedz, P.; Mourad, M.; Gaudard, P.; Eliet, J.; Zeroual, N.; Colson, P.; Ostadal, P.; Mlcek, M.; Hrachovina, M.; Kruger, A.; Vondrakova, D.; Janotka, M.; Mates, M.; Hala, P.; Kittnar, O.; Neuzil, P.; Jacky, A.; Rudiger, A.; Spahn, D. R.; Bettex, D. A.; Kara, A.; Akin, S.; Dos reis Miranda, D.; Struijs, A.; Caliskan, K.; van Thiel, R. J.; Dubois, E. A.; de Wilde, W.; Zijlstra, F.; Gommers, D.; Ince, C.; Marca, L.; Xini, A.; Mongkolpun, W.; Cordeiro, C. P. R.; Leite, R. T.; Lheureux, O.; Bader, A.; Rincon, L.; Santacruz, C.; Preiser, J. C.; Chao, A.; Chao, A. S.; Chen, Y. S.; Kim, W.; Ahn, C.; Cho, Y.; Lim, T. H.; Oh, J.; Choi, K. S.; Jang, B. H.; Ha, J. K.; Mecklenburg, A.; Stamm, J.; Soeffker, G.; Kubik, M.; Sydow, K.; Reichenspurner, H.; Kluge, S.; Braune, S.; Bergantino, B.; Ruberto, F.; Magnanimi, E.; Privato, E.; Zullino, V.; Bruno, K.; Pugliese, F.; Sales, G.; Girotto, V.; Vittone, F.; Brazzi, L.; Fritz, C.; Kimmoun, A.; Vanhuyse, F.; Trifan, B.; Orlowski, S.; Albuisson, E.; Tran, N.; Levy, B.; Chhor, V.; Joachim, J.; Follin, A.; Champigneulle, B.; Chatelon, J.; Fave, G.; Mantz, J.; Pirracchio, R.; Diaz, D. Díaz; Villanova, M.; Aguirregabyria, M.; Andrade, G.; López, L.; Palencia, E.; John, G.; Cowan, R.; Hart, R.; Lake, K.; Litchfield, K.; Song, J. W.; Lee, Y. J.; Cho, Y. J.; Choi, S.; Vermeir, P.; Vandijck, D.; Blot, S.; Mariman, A.; Verhaeghe, R.; Deveugele, M.; Vogelaers, D.; Chok, L.; Bachli, E. B.; Bettex, D.; Cottini, S. R.; Keller, E.; Maggiorini, M.; Schuepbach, R.; Fiks, T.; Stiphout, C.; Grevelink, M.; Vaneker, I.; Ruijter, A.; Buise, M.; Spronk, P. E.; Tena, S. Altaba; Barrachina, L. Galarza; Portillo, J. H. Rodriguez; Aznar, G. Pagés; Campos, L. Mateu; Sellés, M. D. Ferrándiz; Tomás, M. Arlandis; Muncharaz, A. Belenguer; Skinner, L.; Monsalvo, S.; Olavarria, E.; Stümpfle, R.; Na, S. J.; Park, J.; Chung, C. R.; Park, C. M.; Suh, G. Y.; Yang, J. H.; Witter, T.; Brousseau, C.; Butler, M. B.; Erdogan, M.; Dougall, P. C. Mac; Green, R. S.; Abbott, T. E. F.; Torrance, H. D. T.; Cron, N.; Vaid, N.; Emmanuel, J.; Siddiqui, S. S.; Prabu, N.; Chaudhari, H. K.; Patil, V. P.; Divatia, J. V.; Solanki, S.; Kulkarni, A. P.; Gutierrez, L. A. Rincon; Bader, A.; Brasseur, A.; Lheureux, O.; Vincent, J. L.; Creteur, J.; Taccone, F. S.; Hempel, D.; Stauffert, N.; Recker, F.; Schröder, T.; Reusch, S.; Schleifer, J.; Breitkreutz, R.; Sjövall, F.; Perner, A.; Møller, M. Hylander; Moraes, R. B.; Borges, F. K.; Guillen, J. A. V.; Zabaletta, W. J. C.; Ruiz-Ramos, J.; Ramirez, P.; Marqués-Miñana, M. R.; Villarreal, E.; Gordon, M.; Sosa, M.; Concha, P.; Castellanos, A.; Menendez, R.; Ramírez, C. Sánchez; Santana, M. Cabrera; Balcázar, L. Caipe; Escalada, S. Hípola; Viera, M. A. Hernández; Vázquez, C. F. Lübbe; Díaz, J. J. Díaz; Campelo, F. Artiles; Monroy, N. Sangil; Santana, P. Saavedra; Santana, S. Ruiz; Gutiérrez-Pizarraya, A.; Garnacho-Montero, J.; Martin, C.; Baumstarck, K.; Leone, M.; Martín-Loeches, I.; Pirracchio, R.; Legrand, M.; Mainardi, J. L.; Mantz, J.; Cholley, B.; Hubbard, A.; Frontera, P. Ruiz; Vega, L. M. Claraco; Miguelena, P. Ruiz de Gopegui; Usón, M. C. Villuendas; López, A. Rezusta; Clemente, E. Aurensanz; Ibañes, P. Gutiérrez; Aguilar, A. L. Ruiz; Palomar, M.; Olaechea, P.; Uriona, S.; Vallverdu, M.; Catalan, M.; Nuvials, X.; Aragon, C.; Lerma, F. Alvarez; Jeon, Y. D.; Jeong, W. Y.; Kim, M. H.; Jeong, I. Y.; Ahn, M. Y.; Ahn, J. Y.; Han, S. H.; Choi, J. Y.; Song, Y. G.; Kim, J. M.; Ku, N. S.; Bassi, G. Li; Xiol, E. Aguilera; Senussi, T.; Idone, F. A.; Motos, A.; Chiurazzi, C.; Travierso, C.; Fernández-Barat, L.; Amaro, R.; Hua, Y.; Ranzani, O. T.; Bobi, Q.; Rigol, M.; Torres, A.; Fernández, I. Fuentes; Soler, E. Andreu; de Vera, A. Pareja Rodríguez; Pastor, E. Escudero; Hernandis, V.; Ros Martínez, J.; Rubio, R. Jara; Torner, M. Miralbés; Brugger, S. Carvalho; Eroles, A. Aragones; Moles, S. Iglesias; Cabello, J. Trujillano; Schoenenberger, J. A.; Casals, X. Nuvials; Vidal, M. Vallverdu; Garrido, B. Balsera; Martinez, M. Palomar; Mirabella, L.; Cotoia, A.; Tullo, L.; Stella, A.; Di Bello, F.; Di Gregorio, A.; Dambrosio, M.; Cinnella, G.; Rosario, L. E. de la Cruz; Lesmes, S. P. Gómez; Romero, J. C. García; Herrera, A. N. García; Pertuz, E. D. Díaz; Sánchez, M. J. Gómez; Sanz, E. Regidor; Hualde, J. Barado; Hernández, A. Ansotegui; Ramirez, J. Roldán; Takahashi, H.; Kazutoshi, F.; Okada, Y.; Oobayashi, W.; Naito, T.; Baidya, D. K.; Maitra, S.; Anand, R. K.; Ray, B. R.; Arora, M. K.; Ruffini, C.; Rota, L.; Corona, A.; Sesana, G.; Ravasi, S.; Catena, E.; Naumann, D. N.; Mellis, C.; Husheer, S. L.; Bishop, J.; Midwinter, M. J.; Hutchings, S.; Corradi, F.; Brusasco, C.; Manca, T.; Ramelli, A.; Lattuada, M.; Nicolini, F.; Gherli, T.; Vezzani, A.; Young, A.; Carmona, A. Fernández; Santiago, A. Iglesias; Guillamon, L. Navarro; Delgado, M. J. García; Delgado-Amaya, M.; Curiel-Balsera, E.; Rivera-Romero, L.; Castillo-Lorente, E.; Carrero-Gómez, F.; Aguayo-DeHoyos, E.; Healey, A. J.; Cameron, C.; Jiao, L.R.; Stümpfle, R.; Pérez, A.; Martin, S.; del Moral, O. Lopez; Toval, S.; Rico, J.; Aldecoa, C.; Oguzhan, K.; Demirkiran, O.; Kirman, M.; Bozbay, S.; Kosuk, M. E.; Asyralyyeva, G.; Dilek, M.; Duzgun, M.; Telli, S.; Aydin, M.; Yilmazer, F.; Hodgson, L. E.; Dimitrov, B. D.; Stubbs, C.; Forni, L. G.; Venn, R.; Vedage, D.; Shawaf, S.; Naran, P.; Sirisena, N.; Kinnear, J.; Dimitrov, B. D.; Hodgson, L. E.; Stubbs, C.; Forni, L. G.; Venn, R.; Londoño, J. Gonzalez; Cardenas, C. Lorencio; Ginés, A. Sánchez; Gubianas, C. Murcia; Sánchez, E. Clapes; Sirvent, J. M.; Panafidina, V.; Shlyk, I.; Ilyina, V.; Judickas, S.; Kezyte, G.; Urbanaviciute, I.; Serpytis, M.; Gaizauskas, E.; Sipylaite, J.; Sprung, C. L.; Munteanu, G.; Morales, R. C.; Kasdan, H.; Volker, T.; Reiter, A.; Cohen, Y.; Himmel, Y.; Meissonnier, J.; Banderas-Bravo, M. E.; Gómez-Jiménez, C.; García-Martínez, M. V.; Martínez-Carmona, J. F.; Fernández-Ortega, J. F.; O‘Dwyer, M. J.; Starczewska, M.; Wilks, M.; Vincent, J. L.; Torsvik, M.; Gustad, L. T.; Bangstad, I. L.; Vinje, L. J.; Damås, J. K.; Solligård, E.; Mehl, A.; Tsunoda, M.; Kang, M.; Saito, M.; Saito, N.; Akizuki, N.; Namiki, M.; Takeda, M.; Yuzawa, J.; Yaguchi, A.; Frantzeskaki, F.; Tsirigotis, P.; Chondropoulos, S.; Paramythiotou, E.; Theodorakopoulou, M.; Stamouli, M.; Gkirkas, K.; Dimopoulou, I. K.; Makiko, S.; Tsunoda, M.; Kang, M.; Yuzawa, J.; Akiduki, N.; Namiki, M.; Takeda, M.; Yaguchi, A.; Preau, S.; Ambler, M.; Sigurta, A.; Saeed, S.; Singer, M.; Jochmans, S.; Chelly, J.; Vong, L. V. P.; Sy, O.; Serbource-Goguel, J.; Rolin, N.; Weyer, C. M.; Abdallah, R. I.; Adrie, C.; Vinsonneau, C.; Monchi, M.; Mayr, U.; Huber, W.; Karsten, E.; Lahmer, T.; Thies, P.; Henschel, B.; Fischer, G.; Schmid, R. M.; Ediboglu, O.; Ataman, S.; Naz, I.; Yaman, G.; Kirakli, C.; Su, P. L.; Kou, P. S.; Lin, W. C.; Chen, C. W.; Lozano, J. A. Benítez; Sánchez, P. Carmona; Francioni, J. E. Barrueco; Ferrón, F. Ruiz; Simón, J. M. Serrano; Riad, Z.; Mezidi, M.; Aublanc, M.; Perinel, S.; Lissonde, F.; Louf-Durier, A.; Yonis, H.; Tapponnier, R.; Richard, J. C.; Louis, B.; Guérin, C.; Mezidi, M.; Yonis, H.; Aublanc, M.; Lissonde, F.; Louf-Durier, A.; Perinel, S.; Tapponnier, R.; Richard, J. C.; Guérin, C.; Marmanidou, K.; Oikonomou, M.; Nouris, C.; Loizou, C.; Soilemezi, E.; Matamis, D.; Somhorst, P.; Gommers, D.; Hayashi, K.; Hirayama, T.; Yumoto, T.; Tsukahara, K.; Iida, A.; Nosaka, N.; Sato, K.; Ugawa, T.; Nakao, A.; Ujike, Y.; Hirohata, S.; Mojoli, F.; Torriglia, F.; Giannantonio, M.; Orlando, A.; Bianzina, S.; Tavazzi, G.; Mongodi, S.; Pozzi, M.; Iotti, G. A.; Braschi, A.; Jansen, D.; Gadgil, S.; Doorduin, J.; Roesthuis, L.; van der Hoeven, J. G.; Heunks, L. M. A.; Chen, G. Q.; Sun, X. M.; He, X.; Yang, Y. L.; Shi, Z. H.; Xu, M.; Zhou, J. X.; Pereira, S. M.; Tucci, M. R.; Tonelotto, B. F. F.; Simoes, C. M.; Morais, C. C. A.; Pompeo, M. S.; Kay, F. U.; Amato, M. B. P.; Vieira, J. E.; Suzuki, S.; Mihara, Y.; Hikasa, Y.; Okahara, S.; Morimatsu, H.; Kwon, H. M.; Moon, Y. J.; Lee, S. H.; Jung, K. W.; Shin, W. J.; Jun, I. G.; Song, J. G.; Hwang, G. S.; Lee, S.; Moon, Y. J.; Kwon, H. M.; Jung, K.; Shin, W. J.; Jun, I. G.; Song, J. G.; Hwang, G. S.; Ramelli, A.; Manca, T.; Corradi, F.; Brusasco, C.; Nicolini, F.; Gherli, T.; Brianti, R.; Fanzaghi, P.; Vezzani, A.; Tudor, B. A.; Klaus, D. A.; Lebherz-Eichinger, D.; Lechner, C.; Schwarz, C.; Bodingbauer, M.; Seemann, R.; Kaczirek, K.; Fleischmann, E.; Roth, G. A.; Krenn, C. G.; Malyshev, A.; Sergey, S.; Yamaguchi, Y.; Nomura, T.; Yoshitake, E.; Idei, M.; Yoshida, T.; Takaki, S.; Yamaguchi, O.; Kaneko, M.; Goto, T.; Tencé, N.; Zaien, I.; Wolf, M.; Trouiller, P.; Jacobs, F. M.; Kelly, J. M.; Veigas, P.; Hollands, S.; Min, A.; Rizoli, S.; Robles, C. M. Coronado; de Oca Sandoval, M. A. Montes; Tarabrin, O.; Gavrychenko, D.; Mazurenko, G.; Tarabrin, P.; Garcia, I. Palacios; Martin, A. Diaz; Mendez, M. Casado; orden, V. Arellano; Noval, R. Leal; McCue, C.; Gemmell, L.; MacKay, A.; Luján, J.; Villa, P.; Llorente, B.; Molina, R.; Alcázar, L.; Juanas, C. Arenillas; Rogero, S.; Pascual, T.; Cambronero, J. A.; Almudévar, P. Matía; Domínguez, J. Palamidessi; Carmona, S. Alcántara; Castañeda, D. Palacios; Abellán, A. Naharro; Lucendo, A. Pérez; Pérez, L. Pérez; Rivas, R. Fernández; Sanz, N. Martínez; Ramos, J. Veganzones; Villamizar, P. Rodríguez; Javadpour, S.; Kalani, N.; Amininejad, T.; Jamali, S.; Sobhanian, S.; Laurent, A.; Bonnet, M.; Rigal, R.; Aslanian, P.; Hebert, P.; Capellier, G.; Contreras, M. R. Diaz; Mejías, C. Rodriguez; Ruiz, F. C. Santiago; Lombardo, M. Duro; Perez, J. Castaño; de Hoyos, E. Aguayo; Estella, A.; Viciana, R.; Fontaiña, L. Perez; Rico, T.; Madueño, V. Perez; Recuerda, M.; Fernández, L.; Sandiumenge, A.; Bonet, S.; Mazo, C.; Rubiera, M.; Ruiz-Rodríguez, J. C.; Gracia, R. M.; Espinel, E.; Pont, T.; Kotsopoulos, A.; Jansen, N.; Abdo, W. F.; Gopcevic, A.; Gavranovic, Z.; Vucic, M.; Glogoski, M. Zlatic; Penavic, L. Videc; Horvat, A.; Martin-Villen, L.; Egea-Guerero, J. J.; Revuelto-Rey, J.; Aldabo-Pallas, T.; Correa-Chamorro, E.; Gallego-Corpa, A. I.; Granados, P. Ruiz del Portal-Ruiz; Faivre, V.; Wildenberg, L.; Huot, B.; Lukaszewicz, A. C.; Simsir, M.; Mengelle, C.; Payen, D.; Sanz, N. Martinez; Valbuena, B. Lobo; de la Fuente, M. Valdivia; Almudena, P. Matía; Pérez, L. Pérez; Carmona, S. Alcántara; Abellán, A. Navarro; Simón, I. Fernández; Muñoz, J. J. Rubio; Ramos, J. Veganzones; Carmona, S. Alcantara; Almudevar, P. Matia; Abellan, A. Naharro; Lucendo, M. A. Perez; Perez, L. Perez; Dominguez, J. Palamidessi; Rivas, R. Fernandez; Villamizar, P. Rodriguez; Wee, S.; Ong, C.; Lau, Y. H.; Wong, Y.; Banderas-Bravo, M. E.; Olea-Jiménez, V.; Mora-Ordóñez, J. M.; Gómez-Jiménez, C.; Muñoz-Muñoz, J. L.; Vallejo-Báez, J.; Daga-Ruiz, D.; Lebrón-Gallardo, M.; Rialp, G.; Raurich, J. M.; Morán, I.; Martín, M. C.; Heras, G.; Mas, A.; Vallverdú, I.; Hraiech, S.; Bourenne, J.; Guervilly, C.; Forel, J. M.; Adda, M.; Sylla, P.; Mouaci, A.; Gainnier, M.; Papazian, L.; Bauer, P. R.; Kumbamu, A.; Wilson, M. E.; Pannu, J. K.; Egginton, J. S.; Kashyap, R.; Gajic, O.; Yoshihiro, S.; Sakuraya, M.; Hayakawa, M.; Hirata, A.; Kawamura, N.; Tsutui, T.; Yoshida, K.; Hashimoto, Y.; Chang, C. H.; Hu, H. C.; Chiu, L. C.; Hung, C. Y.; Li, S. H.; Kao, K. C.; Sibley, S.; Drover, J.; D’Arsigny, C.; Parker, C.; Howes, D.; Moffatt, S.; Erb, J.; Ilan, R.; Messenger, D.; Ball, I.; Boyd, J. G.; Harrison, M.; Ridi, S.; Muscedere, J.; Andrade, A. H.; Costa, R. C.; Souza, V. A.; Gonzalez, V.; Amorim, V.; Rolla, F.; Filho, C. A. C. Abreu; Miranda, R.; Atchasiri, S.; Buranavanich, P.; Wathanawatthu, T.; Suwanpasu, S.; Bureau, C.; Rolland-Debord, C.; Poitou, T.; Clavel, M.; Perbet, S.; Terzi, N.; Kouatchet, A.; Similowski, T.; Demoule, A.; Diaz, P.; Nunes, J.; Escórcio, S.; Silva, G.; Chaves, S.; Jardim, M.; Câmara, M.; Fernandes, N.; Duarte, R.; Jardim, J. J.; Pereira, C. A.; Nóbrega, J. J.; Chen, C. M.; Lai, C. C.; Cheng, K. C.; Chou, W.; Lee, S. J.; Cha, Y. S.; Lee, W. Y.; Onodera, M.; Nakataki, E.; Oto, J.; Imanaka, H.; Nishimura, M.; Khadjibaev, A.; Sabirov, D.; Rosstalnaya, A.; Akalaev, R.; Parpibaev, F.; Antonucci, E.; Rossini, P.; Gandolfi, S.; Montini, E.; Orlando, S.; van Nes, M.; Karachi, F.; Hanekom, S.; Andrade, A. H.; Pereira, U. V.; Filho, C. A. C. Abreu; Costa, R. C.; Parkin, M. S. W.; Moore, M.; Andrade, A. H.; Costa, R. C.; Carvalho, K. V. Silva; Filho, C. A. C. Abreu; Min, H. J.; Kim, H. J.; Lee, D. S.; Choi, Y. Y.; Lee, E. Y.; Song, I.; Kim, D. J.; E, Y. Y.; Kim, J. W.; Park, J. S.; Cho, Y. J.; Lee, J. H.; Suh, J. W.; Jo, Y. H.; Kim, K. S.; Lee, Y. J.; Ferrero-Calleja, J.; Merino-Vega, D.; González-Jiménez, A. I.; Sigcha, M. Sigcha; Hernández-Tejedor, A.; Martin-Vivas, A.; Gabán-Díez, Á.; Luna, R. Ruiz-de; De la Calle-Pedrosa, N.; Temprano-Gómez, I.; Afonso-Rivero, D.; Pellin-Ariño, J. I.; Algora-Weber, A.; Fumis, R. R. L.; Ferraz, A. B.; Junior, J. M. Vieira; Kirca, H.; Cakin, O.; Unal, M.; Mutlu, H.; Ramazanoglu, A.; Cengiz, M.; Nicolini, E. A.; Pelisson, F. G. F.; Nunes, R. S.; da Silva, S. L.; Carreira, M. M.; Bellissimo-Rodrigues, F.; Ferez, M. A.; Basile-Filho, A.; Chao, H. C.; Chen, C. M.; Chen, L.; Hravnak, M.; Clermont, G.; Pinsky, M.; Dubrawski, A.; Varas, J. Luján; Montero, R. Molina; Sánchez-Elvira, L. Alcázar; Díaz, P. Villa; Delgado, C. Pintado; Ruiz, B. Llorente; Guerrero, A. Pardo; Galache, J. A. Cambronero; Sherif, H.; Hassanin, H.; El Hossainy, R.; Samy, W.; Ly, H.; David, H.; Burtin, P.; Charpentier, C.; Barral, M.; Courant, P.; Fournel, E.; Gaide-Chevronnay, L.; Durand, M.; Albaladejo, P.; Payen, J. F.; Chavanon, O.; Ortiz, A. Blandino; Pozzebon, S.; Lheureux, O.; Brasseur, A.; Vincent, J. L.; Creteur, J.; Taccone, F. S.; Fumagalli, F.; Scala, S.; Affatato, R.; De Maglie, M.; Zani, D.; Novelli, D.; Marra, C.; Luciani, A.; De Zani, D.; Luini, M.; Letizia, T.; Pravettoni, D.; Staszewsky, L.; Masson, S.; Belloli, A.; Di Giancamillo, M.; Scanziani, E.; Latini, R.; Ristagno, G.; Kye, Y. C.; Suh, G. J.; Kwon, W. Y.; Kim, K. S.; Yu, K. M.; Babini, G.; Ristagno, G.; Grassi, L.; Fumagalli, F.; Bendel, S.; De Maglie, M.; Affatato, R.; Masson, S.; Latini, R.; Scanziani, E.; Reinikainen, M.; Skrifvars, M.; Kappler, F.; Blobner, M.; Schaller, S. J.; Roasio, A.; Costanzo, E.; Cardellino, S.; Iesu, E.; Cavicchi, F. Zama; Fontana, V.; Nobile, L.; Vincent, J. L.; Creteur, J.; Taccone, F. S.; Park, M.; You, K. M.; Suh, G. J.; Kwon, W. Y.; Ko, S. B.; Kim, K. S.; Xini, A.; Marca, L.; Lheureux, O.; Brasseur, A.; Vincent, J. L.; Creteur, J.; Taccone, F. S.; Beane, A.; Thilakasiri, M. C. K. T.; De Silva, A. P.; Stephens, T.; Sigera, C. S.; Athapattu, P.; Jayasinghe, S.; Padeniya, A.; Haniffa, R.; Santiago, A. Iglesias; Sáez, V. Chica; Ruiz-Ruano, R. de la Chica; González, A. Sánchez; Kunze-Szikszay, N.; Wand, S.; Klapsing, P.; Wetz, A.; Heyne, T.; Schwerdtfeger, K.; Troeltzsch, M.; Bauer, M.; Quintel, M.; Moerer, O.; Cook, D. J.; Rutherford, W. B.; Scales, D. C.; Adhikari, N. K.; Cuthbertson, B. H.; Suzuki, T.; Takei, T.; Fushimi, K.; Iwamoto, M.; Nakagawa, S.; Mendsaikhan, N.; Begzjav, T.; Lundeg, G.; Dünser, M. W.; Romero, D. González; Cabrera, J. L. Santana; Santana, J. D. Martín; Padilla, Y. Santana; Pérez, H. Rodríguez; Torrent, R. Lorenzo; Kleinpell, R.; Chouris, I.; Radu, V.; Stougianni, M.; Lavrentieva, A.; Lagonidis, D.; Price, R. D. T.; Day, A.; Arora, N.; Henderson, M. A.; Hickey, S.; Costa, M. I. Almeida; Carvalho, J. P.; Gomes, A. A.; Mergulhão, P. J.; Chan, K. K. C.; Shum, H. P.; Yan, W. W.; Maghsoudi, B.; Tabei, S. H.; Masjedi, M.; Sabetian, G.; Tabatabaei, H. R.; Akbarzadeh, A.; Saigal, S.; Pakhare, A.; Joshi, R.; Pattnaik, S. K.; Ray, B.; Rousseau, A. F.; Michel, L.; Bawin, M.; Cavalier, E.; Reginster, J. Y.; Damas, P.; Bruyere, O.; Zhou, J. C.; Cauwenberghs, H.; De Backer, A.; Neels, H.; Deblier, I.; Berghmans, J.; Himpe, D.; Barea-Mendoza, J. A.; Portillo, I. Prieto; Fernández, M. Valiente; Gigorro, R. Garcia; Vela, J. L. Perez; Mateos, H. Marín; Alves, S. Chacón; Varas, G. Morales; Rodriguez-Biendicho, A.; Carreño, E. Renes; González, J. C. Montejo; Yang, J. S.; Chiang, C. H.; Hung, W. T.; Huang, W. C.; Cheng, C. C.; Lin, K. C.; Lin, S. C.; Chiou, K. R.; Wann, S. R.; Lin, K. L.; Kang, P. L.; Mar, G. Y.; Liu, C. P.; Zhou, J. C.; Choi, Y. J.; Yoon, S. Z.; Gordillo-Brenes, A.; Fernandez-Zamora, M. D.; Perez-Borrero, L.; Arias-Verdu, M. D.; Aguilar-Alonso, E.; Herruzo-Aviles, A.; Garcia-Delgado, M.; Hinojosa-Perez, R.; Curiel-Balsera, E.; Rivera-Fernandez, R.; Lesmes, S. P. Gómez; Rosario, L. E. De la Cruz; Hernández, A. Ansotegui; Herrera, A. N. García; Sanz, E. Regidor; Sánchez, M. J. Gómez; Hualde, J. Barado; Pascual, O. Agudo; León, J. P. Tirapu; Irazabal, J. M. Guergue; Pérez, A. González; Fernández, P. Alvarez; Amor, L. Lopéz; Albaiceta, G. Muñiz; Lesmes, S. P. Gómez; Rosario, L. E. De la Cruz; Hernández, A. Ansotegui; Sanz, E. Regidor; Sánchez, M. J. Gómez; Calvo, S. Aldunate; Herrera, A. N. García; Hualde, J. Barado; Pascual, O. Agudo; León, J. P. Tirapu; Corona, A.; Ruffini, C.; Spazzadeschi, A.; Marrazzo, F.; Gandola, A.; Sciurti, R.; Savi, C.; Catena, E.; Ke, M. W.; Cheng, C. C.; Huang, W. C.; Chiang, C. H.; Hung, W. T.; Lin, K. C.; Lin, S. C.; Wann, S. R.; Chiou, K. R.; Tseng, C. J.; Kang, P. L.; Mar, G. Y.; Liu, C. P.; Bertini, P.; De Sanctis, F.; Guarracino, F.; Bertini, P.; Baldassarri, R.; Guarracino, F.; Buitinck, S. H.; van der Voort, P. H. J.; Oto, J.; Nakataki, E.; Tsunano, Y.; Izawa, M.; Tane, N.; Onodera, M.; Nishimura, M.; Ghosh, S.; Gupta, A.; De Gasperi, A.; Mazza, E.; Limuti, R.; Prosperi, M.; Bissenova, N.; Yergaliyeva, A.; Talan, L.; Yılmaz, G.; Güven, G.; Yoruk, F.; Altıntas, N. D.; Mukherjee, D. N.; Agarwal, L. K.; Mandal, K.; Palomar, M.; Balsera, B.; Vallverdu, M.; Martinez, M.; Garcia, M.; Castellana, D.; Lopez, R.; Barcenilla, F.; Kaminsky, G. E.; Carreño, R.; Escribá, A.; Fuentes, M.; Gálvez, V.; Del Olmo, R.; Nieto, B.; Vaquerizo, C.; Alvarez, J.; De la Torre, M. A.; Torres, E.; Bogossian, E.; Nouer, S. Aranha; Salgado, D. Ribeiro; Brugger, S. Carvalho; Jiménez, G. Jiménez; Torner, M. Miralbés; Vidal, M. Vallverdú; Garrido, B. Balsera; Casals, X. Nuvials; Gaite, F. Barcenilla; Cabello, J. Trujillano; Martínez, M. Palomar; Doganci, M.; Izdes, S.; Besevli, S. Guzeldag; Alkan, A.; Kayaaslan, B.; Ramírez, C. Sánchez; Balcázar, L. Caipe; Santana, M. Cabrera; Viera, M. A. Hernández; Escalada, S. Hípola; Vázquez, C. F. Lübbe; Penichet, S. M. Marrero; Campelo, F. Artiles; López, M. A. De La Cal; Santana, P. Saavedra; Santana, S. Ruíz; Repessé, X.; Artiguenave, M.; Paktoris-Papine, S.; Espinasse, F.; Dinh, A.; El Sayed, F.; Charron, C.; Géri, G.; Vieillard-Baron, A.; Marmanidou, K.; Oikonomou, M.; Nouris, C.; Dimitroulakis, K.; Soilemezi, E.; Matamis, D.; Ferré, A.; Guillot, M.; Teboul, J. L.; Lichtenstein, D.; Mézière, G.; Richard, C.; Monnet, X.; Pham, T.; Beduneau, G.; Schortgen, F.; Piquilloud, L.; Zogheib, E.; Jonas, M.; Grelon, F.; Runge, I.; Terzi, N.; Grangé, S.; Barberet, G.; Guitard, P. G.; Frat, J. P.; Constan, A.; Chrétien, J. M.; Mancebo, J.; Mercat, A.; Richard, J. C. M.; Brochard, L.; Prīdāne, S.; Sabeļņikovs, O.; Mojoli, F.; Orlando, A.; Bianchi, I.; Torriglia, F.; Bianzina, S.; Pozzi, M.; Iotti, G. A.; Braschi, A.; Beduneau, G.; Pham, T.; Schortgen, F.; Piquilloud, L.; Zogheib, E.; Jonas, M.; Grelon, F.; Runge, I.; Terzi, N.; Grangé, S.; Barberet, G.; Guitard, P. G.; Frat, J. P.; Constan, A.; Chrétien, J. M.; Mancebo, J.; Mercat, A.; Richard, J. C. M.; Brochard, L.; Kondili, E.; Psarologakis, C.; Kokkini, S.; Amargianitakis, V.; Babalis, D.; Chytas, A.; Chouvarda, I.; Vaporidi, K.; Georgopoulos, D.; Trapp, O.; Kalenka, A.; Mojoli, F.; Orlando, A.; Bianchi, I.; Torriglia, F.; Bianzina, S.; Pozzi, M.; Iotti, G. A.; Braschi, A.; Lozano, J. A. Benítez; Sánchez, P. Carmona; Francioni, J. E. Barrueco; Ferrón, F. Ruiz; Simón, J. M. Serrano; Spadaro, S.; Karbing, D. S.; Gioia, A.; Moro, F.; Corte, F. Dalla; Mauri, T.; Volta, C. A.; Rees, S. E.; Petrova, M. V.; Mohan, R.; Butrov, A. V.; Beeharry, S. D.; Vatsik, M. V.; Sakieva, F. I.; Gobert, F.; Yonis, H.; Tapponnier, R.; Fernandez, R.; Labaune, M. A.; Burle, J. F.; Barbier, J.; Vincent, B.; Cleyet, M.; Richard, J. C.; Guérin, C.; Shinotsuka, C. Righy; Creteur, J.; Taccone, F. S.; Törnblom, S.; Nisula, S.; Vaara, S.; Poukkanen, M.; Andersson, S.; Pettilä, V.; Pesonen, E.; Xie, Z.; Liao, X.; Kang, Y.; Zhang, J.; Kubota, K.; Egi, M.; Mizobuchi, S.; Hegazy, S.; El-Keraie, A.; El Sayed, E.; El Hamid, M. Abd; Rodrigues, N. J.; Pereira, M.; Godinho, I.; Gameiro, J.; Neves, M.; Gouveia, J.; e Silva, Z. Costa; Lopes, J. A.; Mckinlay, J.; Kostalas, M.; Kooner, G.; Dudas, G.; Horton, A.; Kerr, C.; Karanjia, N.; Creagh-Brown, B.; Forni, L.; Yamazaki, A.; Ganuza, M. Sanz; Molina, J. A. Martinez; Martinez, F. Hidalgo; Freile, M. T. Chiquito; Fernandez, N. Garcia; Travieso, P. Medrano; Bandert, A.; Frithiof, R.; Lipcsey, M.; Smekal, D.; Schlaepfer, P.; Durovray, J. D.; Plouhinec, V.; Chiappa, C.; Bellomo, R.; Schneider, A. G.; Mitchell, S.; Durrant, J.; Street, H.; Dunthorne, E.; Shears, J.; Caballero, C. Hernandez; Hutchison, R.; Schwarze, S.; Ghabina, S.; Thompson, E.; Prowle, J. R.; Kirwan, C. J.; Gonzalez, C. A.; Pinto, J. L.; Orozco, V.; Patiño, J. A.; Garcia, P. K.; Contreras, K. M.; Rodriguez, P.; Echeverri, J. E. title: ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016 date: 2016-09-29 journal: Intensive Care Med Exp DOI: 10.1186/s40635-016-0100-7 sha: doc_id: 14533 cord_uid: 6qfecv5h nan months is better than Cole's formula. keywords: acute; admission; adult patients; age; aki; analysis; ards patients; arrest; blood; c. a.; c. c.; c. m.; cardiac; care; care patients; care unit; cases; clinical; complications; conclusions; control; criteria; data; days; death; differences; discharge; duration; end; factors; failure; group; hospital; hospital mortality; hours; icu admission; icu mortality; icu patients; icu stay; impact; incidence; increased; infection; injury; intensive; introduction; j. a.; j. c.; j. e.; j. f.; j. g.; j. j.; j. l.; j. m.; j. p.; j. s.; length; level; lung; m. a.; m. d.; m. e.; m. m.; mean; median; medical; methods; mortality; non; number; objectives; organ; outcome; p =; patients; peep; period; post; pressure; quality; rate; results; resuscitation; risk; s. c.; s. m.; score; sepsis; septic; shock; standard; stay; study; surgery; surgical; survival; system; test; therapy; time; total; treatment; unit; use; value; ventilation; volume; weaning; y. j.; years cache: cord-014533-6qfecv5h.txt plain text: cord-014533-6qfecv5h.txt item: #86 of 449 id: cord-014538-6a2pviol author: Kamilia, Chtara title: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date: 2017-01-10 words: 61107 flesch: 45 summary: We included ICU patients admitted for acute hypoxemic respiratory failure from a previous prospective trial [1] in whom FiO 2 was measured under oxygen mask using a portable oxygen analyzer. Introduction Relative adrenal insufficiency (RAI) is common in ICU patients, particularly during septic shock (1). keywords: acute; admission; adult patients; age; aim; analysis; ards patients; arrest; blood; cardiac; care; care unit; cases; cause; children; clinical; conclusion; criteria; data; days; diagnosis; discussion; disease; duration; extubation; factors; failure; fluid; group; hospital; icu; icu admission; icu mortality; icu patients; incidence; infection; injury; intensive; introduction; jean; low; lung; management; mean; mechanical; median; medical; methods; mortality; n =; niv; non; nutrition; occurrence; outcome; oxygen; p =; patients; period; pierre; pneumonia; pressure; pulmonary; rate; renal; results; risk; score; sepsis; shock; shock patients; significant; stay; studies; study; study period; support; syndrome; therapy; time; treatment; unit; use; vap; ventilation; weaning; years cache: cord-014538-6a2pviol.txt plain text: cord-014538-6a2pviol.txt item: #87 of 449 id: cord-014540-27hnlu5v author: Sutthiruk, Nantanit title: Abstracts from the 8th International Congress of the Asia Pacific Society of Infection Control (APSIC): Bangkok, Thailand. 12-15 February 2017 date: 2017-02-22 words: 24575 flesch: 43 summary: Following the interventions, environmental cleaning assessment of high-touch areas showed an overall average of 86% compliance, with 17 CB-DCs achieving ≥85% compliance in environmental cleaning of high-touch areas. However, in some cases, the difference between S. aureus from different MLST types were much lower -28% (ST239-ST609), 14% (ST8-ST239), 11% (ST8-ST609) and 5% (ST5-ST105). keywords: 6(suppl; antibiotic; associated; background; blood; care; cases; chen; cleaning; compliance; contamination; control; data; days; dose; hand; hand hygiene; hcws; healthcare; hospital; hygiene; incidence; infection; infection control; intervention; isolates; medical; methods; mrsa; nurses; patients; practice; prevention; process; program; rate; resistance; results; risk; ssi; staff; study; system; test; total; treatment; use; vap; workers; years cache: cord-014540-27hnlu5v.txt plain text: cord-014540-27hnlu5v.txt item: #88 of 449 id: cord-014670-e31g8lns author: None title: Poster Sessions 313-503 date: 2004-10-05 words: 28600 flesch: 52 summary: We develop a systematic data collection of all the admitted patients in our ICU through a home-made software and database leading to a broad description of the population and activities of the ICU during the last five years; this was correlated with the classical scoring systems of ICU patients. At the first session, the participants were proposed to imagine a situation starting from one of 2 pictures of ICU patient. keywords: acute; admission; age; analysis; blood; brain; cardiac; care; data; days; dose; dysfunction; failure; fluid; group; hospital; hours; icu; injury; intensive; level; lung; mean; medical; min; mortality; non; outcome; parameters; patients; period; pressure; pts; rate; ratio; results; score; sepsis; septic; stay; study; surgery; system; therapy; treatment; unit; university; use; values; ventilation; volume cache: cord-014670-e31g8lns.txt plain text: cord-014670-e31g8lns.txt item: #89 of 449 id: cord-014685-ihh30q6f author: None title: Posters P788 - P999 date: 2005-09-21 words: 38408 flesch: 42 summary: 12 physical property parameters of protein structure were chosen to construct a 12-dimension physical property space. These systems have proven to be also valuable as membrane mimetic structures, as promising matrices for controlled-release and delivery of proteins, vitamins and small drugs in pharmacological applications, and they offer a 3D lipid matrix for successful crystallization of membrane proteins which do not easily crystallize in bulk solution. keywords: activity; aggregation; analysis; beta; binding; cells; changes; complex; complexes; concentration; conformational; data; delivery; dna; domain; drug; dynamics; effect; energy; experiments; folding; function; human; institute; interaction; light; lipid; loop; mechanism; membrane; membrane protein; method; model; molecular; native; new; nmr; order; peptide; phase; potential; presence; process; properties; protein; protein structure; region; residues; results; rna; rst; sequence; signi; site; solution; speci; stability; state; step; structure; studies; study; surface; system; temperature; terminal; time; transition; transport; type; unfolding; university; uorescence; water; work cache: cord-014685-ihh30q6f.txt plain text: cord-014685-ihh30q6f.txt item: #90 of 449 id: cord-014687-0am4l5ms author: None title: SPR 2012 date: 2012-03-29 words: 98702 flesch: 39 summary: Image Gently has succeeded not only in raising awareness of the great diagnostic benefits we can offer to pediatric patients but also directs us to acknowledge the downside of overzealous diagnostic efforts where excessive radiation becomes a risk. Methods & Materials: Pediatric patients who had high temporal resolution cine Steady State Free Precession sequence (50 frames acquired across a single cardiac cycle) performed as part of a MRI/MRA of the heart from 2005-2011 were included. keywords: abnormalities; acute; age; airway; anatomy; anomalies; appearance; approach; assessment; average; blood; body; bone; bowel; brain; brain mri; cardiac; care; case report; cases; center; chest; children; complications; conclusions; conditions; contrast; correlation; ct imaging; data; days; development; diagnosis; diffusion; disease; disorders; dose; evaluation; exhibit; fat; fetal; flow; follow; following; fractures; group; head; heart; high; hospital; images; imaging; imaging features; imaging findings; imaging modalities; imaging studies; infants; information; injury; institution; left; lesions; level; literature; liver; low; lung; malformations; management; mass; masses; materials; mean; medical; methods; months; mr imaging; mri; mri findings; neck; neonatal; new; noise; non; obstruction; pathology; patients; pediatric; population; post; posterior; potential; prenatal; present; presentation; protocol; pulmonary; purpose; quality; radiation; radiographs; radiologists; radiology; range; renal; resolution; resonance imaging; results; review; right; role; scan; size; spectrum; spinal; spine; spr; studies; study; surgery; syndrome; system; technique; time; tissue; treatment; tumor; ultrasound; university; use; value; vascular; venous; years cache: cord-014687-0am4l5ms.txt plain text: cord-014687-0am4l5ms.txt item: #91 of 449 id: cord-014794-yppi30a0 author: None title: 19th European Congress of Pathology, Ljubljana, Slovenia, September 6-11, 2003 date: 2003-07-31 words: 158305 flesch: 41 summary: The comparison in paired tumor and normal tissue samples showed that phosphorylated ERK-1/ERK-2 expression was higher in tumor cells as compared to surrounding normal salivary parenchyma. IRF-1 derepression by invading tumor cells was associated with poor prognosis. keywords: actin; activity; adenocarcinoma; aim; alpha; analysis; antibodies; antibody; antigen; apoptosis; apoptotic; areas; associated; association; bcl-2; benign; biopsies; biopsy; bladder; blood; bone; breast; breast cancer; breast carcinoma; cancer; cancer cells; cancer patients; carcinoma; cases; cases introduction; cd10; cell carcinoma; cell lymphoma; cell proliferation; cells; changes; chronic; classification; clinical; colorectal; conclusion; control; correlation; cyclin; data; department; detection; development; diagnosis; differences; differentiation; diffuse; disease; dna; electron; epithelial; evaluation; examination; expression; factor; features; female; fibrosis; findings; follow; gastric; gene expression; genes; gland; grade; group; growth; hospital; hpv; human; immunohistochemistry; immunoreactivity; index; infection; inflammatory; introduction; invasion; involvement; ki-67; kit; left; lesions; levels; like; liver; lung; lymph; lymphocytes; lymphoma; malignant; markers; mass; material; mean; metastases; metastatic; methods; microscopy; monoclonal; months; mucosa; muscle; negative; neoplasms; node; non; normal; nuclear; nuclei; number; ovarian; overexpression; p53; p53 expression; papillary; paraffin; parameters; pathology; patients; pattern; pcr; positive; positivity; presence; present; primary; prognostic; progression; proliferation; prostate; protein expression; proteins; receptor; renal; report; results; right; risk; role; samples; sections; series; significance; size; skin; smooth; specific; specimens; stage; staining; status; stromal; studies; study; surgery; survival; system; thyroid; time; tissue; total; treatment; tumor cells; tumors; tumour; type; university; value; vascular; vegf; vessels; women; years cache: cord-014794-yppi30a0.txt plain text: cord-014794-yppi30a0.txt item: #92 of 449 id: cord-014987-nycbjqn6 author: None title: OP 0364-0412 date: 2006-08-24 words: 9808 flesch: 52 summary: Patients with Septic Shock also had a significantly lower oxygen consumption rate when compared to healthy volunteers or patients with SIRS (p<0.001 and p=0.002 respectively. Patients with adequate therapy were older than patients with initial inadequate antibiotic therapy (41.4±21.1 vs 60.5±16.6; p<0.01) but the APACHE II at admission was the same in both groups (21 vs 18'4; p=ns). keywords: admission; care; data; group; hospital; hours; icu; intensive; mean; medical; mortality; outcome; patients; sepsis; study; therapy; vap; ventilation cache: cord-014987-nycbjqn6.txt plain text: cord-014987-nycbjqn6.txt item: #93 of 449 id: cord-014996-p6q0f37c author: None title: Posters_Monday_12 October 2009 date: 2009-08-06 words: 85276 flesch: 51 summary: ICU patients with acute respiratory failure requiring NIV were studied during three randomized consecutive 20 min-periods of NIV: ICU ventilator with and without NIV mode and NIV ventilator. EFL was recorded in 65% of ICU patients with pulmonary diseases: 65 % of ARDS patients, 75% of patients with respiratory infection, 75% of asthmatics and 85% of patients with COPD. keywords: acute; admission; adult patients; age; aim; analysis; apache; arterial; blood; cardiac; care; care patients; conclusion; control; data; days; diagnosis; differences; duration; early; failure; fluid; group; high; hospital; hospital mortality; icu; icu admission; icu mortality; icu patients; icu stay; incidence; infection; injury; intensive; introduction; lactate; length; levels; low; lung; mean; median; medical; methods; min; model; mortality; n =; non; number; objectives; organ; outcome; oxygen; p =; parameters; patients; pct; period; pneumonia; pressure; pulmonary; rate; renal; respiratory; results; risk; score; sepsis; septic; serum; shock; shock patients; stay; study; surgery; system; test; therapy; time; total; trauma patients; treatment; unit; use; vap; ventilation; volume; years cache: cord-014996-p6q0f37c.txt plain text: cord-014996-p6q0f37c.txt item: #94 of 449 id: cord-015021-pol2qm74 author: None title: Third International Congress on the Immune Consequences of Trauma, Shock and Sepsis —Mechanisms and Therapeutic Approaches date: 1994 words: 162543 flesch: 45 summary: Ever since we know the role of endotoxins in the pathophysiology of sepsis, antibodies against the S-and R-LPS have also been detected in sepsis patients. In sepsis patients, the CD]4+/CD16+ cells can become a major population with more than 50% of all monocytes in 3 of 18 patients and with more than 500 cells/mm 3 in 4 of 18 cases. keywords: acid; activation; activity; acute; addition; adhesion; administration; aim; analysis; animals; anti; antibodies; antibody; ards; arterial; bacteria; binding; blood; blood cells; blood levels; blood samples; body; burn; capacity; cardiac; cause; cd14; cells; cellular; challenge; changes; circulating; clinical; clp; complement; complications; concentrations; conclusion; conditions; contrast; control; control group; control patients; correlation; course; csf; cultured; cytokine levels; cytokine production; cytokines; damage; data; days; death; decrease; development; differences; disease; dose; dysfunction; effect; elevated; elisa; endothelial; endotoxin; endotoxin levels; evidence; experimental; expression; factor; failure; flow; following; formation; function; gene; gram; group; growth; gut; hepatic; high; host; hours; hrs; human; il-1; il-6; il-6 levels; il-8; ill; immune; increased; induction; infection; inflammation; inflammatory; infusion; inhibitor; injury; ischemia; leukocytes; levels; lipid; liver; lps; lung; lymphocytes; macrophages; mean; mechanisms; mediators; membrane; methods; mice; model; mof; molecules; monoclonal; monocytes; mortality; multiple; necrosis; negative; neutrophils; new; non; normal; number; operation; organ; organ failure; organ injury; outcome; oxygen; p<0.05; parameters; patients; period; peritoneal; phase; placebo; plasma; plasma levels; plasma tnf; play; pmn; positive; post; postoperative; potential; presence; present; pressure; process; production; protein; pulmonary; rate; rats; receptor; reduced; related; release; reperfusion; response; results; risk; role; saline; samples; score; sepsis; sepsis patients; septic; serum; serum levels; severity; sham; shock; sirs; soluble; specific; state; stimulation; studies; study; surface; surgery; survival; syndrome; synthesis; system; systemic; t cells; test; therapeutic; therapy; time; tissue; tnf; tnf levels; tnf production; tnf release; total; trauma patients; treated; treatment; tumor; type; use; values; vascular; vitro; vivo; wound cache: cord-015021-pol2qm74.txt plain text: cord-015021-pol2qm74.txt item: #95 of 449 id: cord-015024-2xzc0uc5 author: None title: ESICM 2010 WEDNESDAY SESSIONS 13 October 2010 date: 2010-08-31 words: 84465 flesch: 50 summary: The primary end point of this study was to evaluate the RVD of the IVC in ICU patients with spontaneous breathing. ICU patient with spontaneous breathing and signs of hypoperfusion (oliguria, mottles, serum lactate level [2 mmol/l) were eligible after the approval of the local Ethics Committee. keywords: acute; administration; admission; age; aim; analysis; apache; baseline; blood; cardiac; care; care patients; care unit; changes; clinical; conclusions; control; critical; data; day; days; death; difference; discharge; dose; effect; factors; failure; fluid; following; function; group; hemodynamic; high; hospital; icu admission; icu patients; incidence; increase; infusion; injury; intensive; introduction; levels; low; lung; management; mean; median; medical; methods; min; months; mortality; n =; non; number; nurses; objectives; outcome; p =; parameters; patients; period; plasma; post; pressure; pulmonary; rate; response; results; resuscitation; risk; score; sepsis; septic; serum; shock; shock patients; stay; study; support; surgery; test; therapy; time; total; treatment; unit; use; values; ventilation; volume; years cache: cord-015024-2xzc0uc5.txt plain text: cord-015024-2xzc0uc5.txt item: #96 of 449 id: cord-015082-l629n8is author: None title: Poster Sessions 323-461 date: 2002-08-29 words: 26609 flesch: 50 summary: Isoflurane sedation of ICU patients has previously been shown to be useful but has not come into wide clinical use for a number of reasons. Isoflurane administered via the ACD for sedation of ICU patients is environmentally safe, requires small volumes of isoflurane and may provide better quality of sedation than midazolam. keywords: acute; admission; age; analysis; blood; cardiac; care; complications; control; data; days; effect; group; hospital; hours; icu; increase; injury; levels; mean; methods; min; mortality; outcome; patients; postoperative; pressure; protein; rate; rats; response; results; score; sepsis; septic; shock; stay; study; surgery; test; time; trauma; treatment; years cache: cord-015082-l629n8is.txt plain text: cord-015082-l629n8is.txt item: #97 of 449 id: cord-015090-n6f4xupw author: None title: PS 339-563 date: 2005-09-10 words: 26303 flesch: 51 summary: Propofol is often used as a sedative in ICU patients. The aim of this study was to suggest how the computation of ÄSID should be sophisticated in order to obtain a good correspondence with BE in ICU patients. keywords: admission; age; aim; analysis; blood; brain; cardiac; care; cases; changes; conclusion; costs; data; days; group; hospital; hours; icu; intensive; levels; mean; medical; methods; mortality; non; organ; outcome; patients; period; pressure; rate; risk; score; sepsis; shock; stay; study; surgery; test; time; trauma; tube; unit; university; use; ventilation cache: cord-015090-n6f4xupw.txt plain text: cord-015090-n6f4xupw.txt item: #98 of 449 id: cord-015126-cyhcbk1j author: None title: PS 0036-0344 date: 2007-08-25 words: 59258 flesch: 52 summary: The aim of this clinical trial is to study CIP in ICU patients (pts) after surgical procedures. The physiological condition of ICU patients is marked by rapidly evolving and frequently life-threatening derangements as well as 'silent' yet important alterations in homeostasis. keywords: acute; admission; age; aim; analysis; apache; arterial; baseline; blood; care; cases; changes; conclusion; control; data; days; disease; early; effects; end; factors; failure; fio2; flow; fluid; glucose; group; high; hospital; hours; icu; icu patients; increase; index; infection; infusion; injury; intensive; level; lung; mean; median; medical; min; model; mortality; non; outcome; parameters; patients; period; pressure; pts; rate; respiratory; results; risk; score; sepsis; septic; shock; shock patients; stay; study; support; surgery; system; test; therapy; time; total; trauma; treatment; unit; use; values; ventilation; volume; years cache: cord-015126-cyhcbk1j.txt plain text: cord-015126-cyhcbk1j.txt item: #99 of 449 id: cord-015147-h0o0yqv8 author: None title: Oral Communications and Posters date: 2014-09-12 words: 73903 flesch: 39 summary: After 3 months of exposures, inflammatory cells in bronchoalveolar lavage fluid were increased in both the HCR-and LCR-smokeexposed(SE) animals compared to air-exposed controls (p<0.001); however there was a 2-3-fold increase in the number of neutrophils and lymphocytes in the LCR-over the HCR-SE group (p<0.001).Histopathology revealed there was greater inflammation and lung damage present in the LCR-versus HCR-SE group (p<0.05). This causes the symptoms of the early phase of AI and the onset of the late phase characterized by the penetration in the inflamed tissue of inflammatory cells, notably the eosinophils. keywords: activation; activity; acute; addition; adhesion; administration; aim; alpha; analysis; animals; anti; antibodies; antibody; arthritis; associated; beta; binding; blood; bone; cancer; cartilage; cells; chronic; complex; conditions; control; cox-2; cytokines; data; day; days; development; disease; dose; effect; expression; factor; function; gene; group; hours; human; il-1b; il-6; immune; increase; induction; inflammation; inflammatory; inhibited; inhibition; inhibitors; injection; injury; joint; kinase; leukocyte; levels; lps; lung; macrophages; mechanisms; mediators; methods; mice; mif; model; molecular; molecules; monocytes; mouse; mrna; neutrophils; new; novel; number; p38; pathways; patients; pcr; plasma; potential; presence; present; production; protein; rats; receptor; reduced; regulation; release; research; response; results; rheumatoid; role; selective; serum; signaling; skin; specific; stimulation; studies; study; synthesis; system; t cells; therapeutic; time; tissue; tnf; tnfa; treatment; tumor; type; university; vitro; vivo cache: cord-015147-h0o0yqv8.txt plain text: cord-015147-h0o0yqv8.txt item: #100 of 449 id: cord-015306-us58wwmp author: None title: Abstracts for the IPNA Congress, 30 August - 3 September 2013, Shanghai, China date: 2013-06-21 words: 71292 flesch: 48 summary: The purpose of this study was to determine the diagnostic performance of the application of questionnaires to detect ADHD and other psychiatric disorders in children with functional voiding disorders in general pediatrics consultations Methods: The study was conducted on 32 children between 6 and 13 years of age (20 males) diagnosed with FVD (patient group) and 32 children of the same age (21 males) who had no urinary symptoms (control group). Conclusion: Converting from a CNI based immunosuppressant protocol for Paediatric renal transplantation patients to a Sirolimus based one was effective and the benefit was shown up to 54 months post-transplantation One patient received a desensitisation regime with Rituximab and plasmaexhange pre-transplant and IV immunoglobulin post-operatively. keywords: abstract; acute; age; aki; analysis; biopsy; bladder; blood; cases; cells; children; chronic; ckd; conclusion; control group; correlation; creatinine; data; days; dialysis; difference; disease; dose; ebv; effect; enuresis; expression; factors; failure; findings; follow; function; gene; glomerular; grade; graft; group; group b; growth; hospital; hsp; igan; infection; injury; kidney; kidney disease; kidney injury; levels; mean; median; medical; methods; model; months; mutations; nephrology; nephropathy; nocturnal; non; objective; patients; pediatric; period; post; primary; proteinuria; range; rate; rats; recipients; renal; results; risk; role; serum; stage; study; study group; survival; syndrome; term; therapy; time; total; transplantation; treatment; treatment group; tubular; university; urinary; urine; vur; weeks; weight; years cache: cord-015306-us58wwmp.txt plain text: cord-015306-us58wwmp.txt item: #101 of 449 id: cord-015324-y44sfr0c author: None title: Scientific Programme date: 2007-09-01 words: 197844 flesch: 49 summary: In the group I, consisted of 63 infants (35 males and 28 females) PCD increased during the time in 3,2% infants, remained unchanged in 11,1%, decreased in 14,3%, and disappeared in 71,4% patients. There was no significant difference between renal transplant patients and healthy controls in genotype distribution of allelic frequencies of IL-6, FAS and MCP-1 polymorphisms. keywords: abnormalities; according; acid; activity; acute; adult patients; adults; age; aim; analysis; anti; associated; background; baseline; biopsy; blood; body; bone; boys; calcium; cases; cause; cells; changes; childhood; children; chronic; ckd; clinical; complete; conclusion; control; control group; correlation; course; creatinine; crf patients; csa; damage; data; day; days; development; diagnosis; dialysis; dialysis patients; difference; disease; dose; duration; dysfunction; effect; elevated; end; esrd; examination; excretion; expression; factor; failure; family; findings; follow; fsgs; function; gene; gfr; girls; glomerular; glomerulonephritis; grade; graft; group; growth; hd patients; hematuria; history; hospital; human; hus; hypertension; iga; incidence; increase; infants; infection; initial; injury; kidney; kidney disease; levels; male; mean; median; mesangial; metabolic; methods; mice; min/1.73; mmf; months; mrna; mutations; negative; nephritis; nephrology; nephropathy; nephrotic; non; normal; number; objective; onset; outcome; p<0.001; p<0.05; parameters; patients; pcr; pediatric; period; peritoneal; plasma; population; positive; post; prednisone; presence; present; pressure; primary; progression; proteinuria; pth; range; rare; rate; ratio; rats; reflux; rejection; relapse; remission; renal; renal biopsy; renal transplantation; report; response; results; risk; role; second; serum; severe; specific; srns; stage; steroid; studies; study; study group; survival; symptoms; syndrome; system; tacrolimus; term; test; therapy; time; total; tract; transplant patients; transplantation; treated; treatment; tubular; type; ultrasound; urinary; urine; uti; values; vs.; vur; vur patients; weeks; weight; years; yrs cache: cord-015324-y44sfr0c.txt plain text: cord-015324-y44sfr0c.txt item: #102 of 449 id: cord-015334-8p124rwp author: None title: ESCP 36th European Symposium on Clinical Pharmacy ‘Implementing Clinical Pharmacy in Community and Hospital Settings: Sharing the Experience’, Istanbul, Turkey 25–27 October 2007; Abstracts date: 2008-06-11 words: 51170 flesch: 47 summary: The main off-label indications were prevention of hemorrhagic risk of antiplatelet agent (23%), hemoglobin decrease(16%), anticoagulant co-prescription(13%), steroids co-prescription(6%). A rinse volume of 10 ml improved significantly the transit of Mopral Ò , Ogast Ò and Ogastoro Ò (+4.8%, keywords: administration; age; analysis; background; blood; care; cases; community; conclusions; control; criteria; data; days; department; design; disease; dosage; dose; drug; effects; errors; group; guidelines; health; hospital; information; interventions; level; management; mean; measures; medical; medication; months; new; non; number; nurses; objective; oral; order; outcome; outcome measures; pain; patients; period; pharmaceutical; pharmacists; pharmacy; physicians; practice; prescriptions; problems; quality; questionnaire; recommendations; results; risk; safety; setting; studies; study; therapy; time; total; treatment; use; years cache: cord-015334-8p124rwp.txt plain text: cord-015334-8p124rwp.txt item: #103 of 449 id: cord-015335-l0kjxhd1 author: None title: Irish Society of Gastroenterology: Proceedings for summer meeting – 26th/27th May 1995 in Galway date: 1995 words: 8736 flesch: 49 summary: It is postulated that cells may be of the Th2 phenotype in normal subjects and coeliac patients with inactive disease (due to the observed increase in IL6 in the absence of IFN~t production) The differences between the IBS group (42.8 + 5.6 yr) and the controls or the CD and UC patients were not statistically significant. keywords: age; cell; coeliac; controls; disease; group; liver; mean; non; normal; patients; range; secretion; study; subjects; treatment; tumour cache: cord-015335-l0kjxhd1.txt plain text: cord-015335-l0kjxhd1.txt item: #104 of 449 id: cord-015348-qt0worsl author: None title: Abstract date: 2010-07-30 words: 74228 flesch: 40 summary: The role of autophagy in cancer seems to be dual: On one hand, there is a growing body of evidence supporting the idea that autophagy may represent a tumor suppressor mechanism by reducing intratumoral necrosis, restricting oxidative stress and limiting chromosomal instability; on the other hand, autophagy may be an important process used by tumor cells to escape various types of stress and even therapeutic agents. At a higher magnification, tumor cells are grouped in small nests formed by large cells, with an abundant, pale, mucus-laden cytoplasm and an eccentric nucleus. keywords: adenocarcinoma; age; aim; analysis; antibodies; antibody; benign; biopsies; biopsy; brain; breast; breast cancer; cancer; carcinoma; cases; cells; changes; chronic; clinical; colorectal; conclusion; control; correlation; cystic; data; dept; development; diagnosis; disease; egfr; epithelial; evaluated; evaluation; examination; expression; factors; features; findings; gastrointestinal; gene; grade; group; growth; high; hyperplasia; ihc; immunohistochemistry; inflammatory; information; kit; lesions; like; lung; lymph; lymphoma; malignant; markers; mass; melanoma; metastatic; method; microscopy; molecular; mutations; new; node; non; nuclear; number; objective; p53; parameters; pathologists; pathology; patients; presence; present; primary; prognostic; proliferation; protein; report; results; risk; role; samples; slides; specimens; stage; staining; stromal; studies; study; system; therapy; time; tissue; treatment; tumor; tumor cells; tumours; type; use; vascular; vegf; years cache: cord-015348-qt0worsl.txt plain text: cord-015348-qt0worsl.txt item: #105 of 449 id: cord-015352-2d02eq3y author: None title: ESPR 2017 date: 2017-04-26 words: 82384 flesch: 43 summary: In 2011, the image gently campaign released a safety checklist for performing digital radiography examinations on pediatric patients which is easily applicable to every radiology service. Health care professionals have a shared responsibility for communicating risks and benefits of imaging procedures to patients, especially in the case of pediatric patients. keywords: accuracy; acute; adc; age; agreement; analysis; anomalies; approach; assessment; biopsy; body; bone; bowel; brain; cases; changes; chest; children; contrast; correlation; cxr; data; diagnosis; diffusion; disease; dose; dwi; edema; evaluation; examination; findings; fluid; follow; group; head; hepatic; high; images; imaging; imaging findings; infection; information; injury; involvement; jia; left; lesions; literature; liver; lung; mass; mean; months; mr imaging; mre; mri; non; normal; objective; patients; pediatric; pneumonia; points; population; positive; possible; post; potential; presence; present; presentation; procedure; pulmonary; radiation; radiologists; radiology; range; renal; results; right; risk; role; sensitivity; sequences; signal; standard; studies; study; symptoms; syndrome; system; technique; time; tissue; total; trauma; treatment; tumor; ultrasound; use; values; vascular; volume; wall; years cache: cord-015352-2d02eq3y.txt plain text: cord-015352-2d02eq3y.txt item: #106 of 449 id: cord-015354-yknwveyz author: None title: Abstracts_Poster presentations date: 2007-09-18 words: 221717 flesch: 51 summary: Results: The AS-IS diagram identified the following pre-scan steps as candidates for a change: i) non-appearance of patients, ii) measurement of body weight and height, calculation of body mass index and sestamibi dose, iii) preparations and check of patient dose, iv) positioning of intravenous cannula and dose injection, v) check of medication and withdrawal of relevant drugs before stress acquisition, and vi) entering of informations into a working sheet and the patient protocol. Patients data were analysed using both Kaplan-Meier event-free survival curves and Cox multivariate analyses. keywords: 18f; 99mtc; accumulation; accuracy; acquisition; activity; administration; aim; analysis; area; artery; assessment; attenuation; average; background; blood; body; bone; bone scintigraphy; brain; brain spect; breast; cad; camera; cancer patients; carcinoma; carcinoma patients; cardiac; cases; cell; changes; chemotherapy; clinical; collimator; comparison; conclusion; contrast; control; coronary; correlation; ct data; ct findings; ct images; ct imaging; ct results; ct scan; ct studies; ct study; data; day; days; decrease; detection; determine; diagnosis; difference; disease; dm patients; dose; dose ct; effect; energy; evaluate; evaluation; examination; factors; fdg pet; fdg uptake; findings; follow; function; gamma; group; group patients; heart; high; hospital; hours; i-131; images; imaging; increased; information; injection; kidney; left; lesions; level; liver; low; lung; lymph; m tc; malignant; management; material; mbq; mci; mean; medical; medicine; metastases; methods; mibi; min; minutes; model; months; mps; mri; myocardial; negative; node; non; normal; nuclear; number; order; pain; parameters; patients; patients scintigraphy; pd patients; perfusion; perfusion scintigraphy; perfusion spect; perfusion study; period; pet; pet ct; pet imaging; pet scan; phantom; phase; planar; positive; post; presence; present; primary; procedure; pts; pulmonary; purpose; quality; radiation; radioiodine; range; rate; ratio; reconstruction; recurrence; region; regional; renal; resolution; respectively; response; rest; results; right; risk patients; scan; scintigraphy; second; sensitivity; sentinel; serum; size; sln; software; specific; specificity; spect; spect data; spect images; spect study; stage; standard; stress; studies; study; study results; subjects; surgery; suv; symptoms; system; technique; test; therapeutic; therapy; thyroid; thyroid cancer; time; tissue; total; tracer; treatment; tumor; type; underwent; university; uptake; use; value; volume; women; years cache: cord-015354-yknwveyz.txt plain text: cord-015354-yknwveyz.txt item: #107 of 449 id: cord-015359-gf32a6f1 author: None title: B scientific sessions (SS) date: 2002 words: 159804 flesch: 47 summary: The PTB accelerates the diagnostic management of ER-and ICU-patients and hence increases CT patient throughput. Non-surgical patients had radiological follow up for minimum 1 year Conclusion: The incidence of malignancy in Bosniak category III is 60.7 % (95 % confidence interval). keywords: abnormalities; accuracy; acquisition; acute; administration; aim; analysis; angiography; aortic; area; arterial; arteries; artery; assessment; axial; biopsy; bladder; blood; bone; bowel; brain; breast; cancer; carcinoma; cardiac; carotid; cases; changes; children; clinical; comparison; complications; conclusion; contrast; contrast enhancement; control; conventional; coronal; coronary; correlation; ct data; ct findings; ct images; ct imaging; ct scans; data; days; detection; detector; diagnosis; diameter; difference; digital; disease; doppler; dose; dsa; dynamic; enhancement; evaluation; examination; field; findings; flow; follow; fractures; function; good; grade; group; hepatic; images; imaging; increase; information; injection; intensity; left; lesions; level; liver; lung; lymph; materials; mean; measurements; metastases; methods; minutes; months; mr images; mr imaging; mra; mri; mri findings; msct; multislice ct; myocardial; n =; new; nodes; non; number; p =; pain; parameters; patients; patients ct; patients mri; perfusion; phase; positive; post; presence; present; procedure; protocol; pulmonary; purpose; quality; r =; radiation; radiologists; range; rate; reconstruction; reduction; renal; resolution; results; scans; score; sensitivity; sequences; siemens; signal; significant; size; slice; specificity; spine; spiral ct; standard; stenosis; stent; studies; study; subjects; surgery; system; t =; technique; therapy; thickness; time; tissue; tool; total; treatment; tumor; tumours; type; ultrasound; underwent; use; values; vascular; venous; volume; wall; weighted; years cache: cord-015359-gf32a6f1.txt plain text: cord-015359-gf32a6f1.txt item: #108 of 449 id: cord-015368-a0qz4tb9 author: None title: 48th Annual Meeting of the Austrian Society of Surgery, Graz, June 7–9, 2007 date: 2007 words: 86712 flesch: 48 summary: In an unselected cohort of surgical patients those presenting with infection prior to surgery and those undergoing abdominal surgery are at highest risk of death from infection. After resection patients should have long term follow up. keywords: acute; age; aim; analysis; aortic; approach; artery; average; background; blood; breast; bypass; cancer; cancer patients; carcinoma; cardiac; cases; cell; chemotherapy; children; colon; colorectal; complications; conclusions; control; data; days; department; der; diagnosis; die; disease; endoscopic; esophageal; experience; expression; female; findings; follow; following; function; gastric; grade; graft; group; heart; hernia; high; hospital; iii; incidence; increase; infection; injuries; laparoscopic; left; lesions; levels; liver; male; management; mean; median; medical; methods; min; months; morbidity; mortality; n ¼; nerve; non; number; operation; outcome; p ¼; pain; patients; period; postoperative; preoperative; present; procedure; quality; range; rate; repair; resection; results; right; risk; skin; stage; standard; stay; study; surgery; surgical; survival; symptoms; system; technique; term; therapy; time; tissue; total; trauma; treatment; tumor; type; valve; vs.; weight; years cache: cord-015368-a0qz4tb9.txt plain text: cord-015368-a0qz4tb9.txt item: #109 of 449 id: cord-015372-76xvzvdg author: None title: National scientific medical meeting 1996 abstracts date: 1996 words: 36628 flesch: 50 summary: Control patients were enrolled who had no clinical evidence of rheumatological disease, A salivary sample was collected and examined by light microscopy. Drug induced photosensitivity may look identical clinically, have a similar history and patients with CAD may be treated with potentially photosensitising drugs. keywords: acid; activity; age; aim; analysis; antibodies; blood; bone; care; cases; cells; children; controls; data; day; difference; disease; drug; expression; females; findings; following; group; hiv; hospital; incidence; increase; infection; irish; levels; males; mean; months; negative; number; pain; patients; pcr; period; population; positive; present; range; rate; response; results; risk; samples; serum; skin; studies; study; subjects; test; therapy; time; total; treatment; type; use; virus; years cache: cord-015372-76xvzvdg.txt plain text: cord-015372-76xvzvdg.txt item: #110 of 449 id: cord-015394-uj7fe5y6 author: None title: Scientific Abstracts date: 2008-12-23 words: 242809 flesch: 48 summary: The highest level of -tubulin acetylation (2.5-fold) was observed with Vinblastine at 10-fold IC 50 after 48 h. Exposure to Microtubule interacting agents and TSA resulted in increased cell surface expression of Ep-CAM in a time and dose dependent manner. Finally, we elucidated a link between the RA and TGF-pathways by assessing the impact of RA treatment of TGF-3 expression, demonstrating that TGF-3 template decreased to levels comparable to myometrial cell expression (0.84±0.12 fold). keywords: acid; activation; activity; addition; administration; adult; aea; age; aim; analysis; animals; anova; anti; antibodies; antibody; apoptosis; arteries; artery; assay; associated; association; background; baseline; binding; birth; blood; blood cells; blot; bmi; body; brain; cancer; cancer cells; cases; cells; center; cervix; cesarean; changes; clinical; collagen; concentrations; conclusions; conditions; contractions; contrast; contribute; control; control cells; control group; correlation; cortisol; crf; culture; cycle; cytokines; data; day; days; decidua; decrease; delivery; design; development; differences; differentiation; disease; dna; dose; effect; elisa; endometriosis; endometrium; endothelial; eoc cells; epithelial; estradiol; estrogen; evidence; explants; exposure; expression; expression levels; factor; fat; female; fetal; fetuses; findings; flow; fluid; fold; following; free; function; gene; gestation; glucose; gnrh; group; growth; gynecology; hcg; high; hormone; hospital; hours; human; hypertension; hypothesis; hypoxia; il-6; il-8; immune; immunohistochemistry; implantation; increase; induction; infection; inflammation; inhibitor; insulin; introduction; invasion; iugr; ivf; kinase; labor; leptin; levels; lps; male; maternal; mean; mechanisms; media; medical; medicine; medium; membranes; menstrual; methods; mice; min; model; mouse; mrna expression; mrna levels; muscle cells; myometrial; n=6; neonatal; new; non; normal; novel; nuclear; number; obesity; objective; obstetrics; offspring; onset; oocytes; outcome; ovarian; oxygen; p<0.001; p<0.05; pathway; patients; pattern; pcos; pcr; period; phase; phosphorylation; placental; placental cells; plasma; play; population; positive; post; potential; preeclampsia; pregnancies; pregnancy; pregnant; presence; present; pressure; preterm; primary; production; progesterone; proliferation; protein expression; protein levels; proteins; range; rate; rats; receptor; receptor expression; reduced; regulation; relative; release; reproductive; response; restriction; results; risk; role; samples; secretion; sections; serum; sheep; signaling; smooth; specific; staining; stress; studies; study; study group; subjects; syndrome; system; t cells; term; test; time; tissue; tnf; total; treatment; trimester; trophoblast cells; tumor; type; university; usa; uterine; uterus; vascular; vegf; vehicle; vitro; vivo; weeks; weight; western; women; years cache: cord-015394-uj7fe5y6.txt plain text: cord-015394-uj7fe5y6.txt item: #111 of 449 id: cord-015569-vy49r1zd author: None title: Abstracts from the 45(th) Annual Meeting of Japanese Association for the Stusy of Taste and Smell (JASTS 2011), Kanazawa, Japan, October 5-7(th), 2011 (The president of the meeting was Dr. Takaki Miwa, Kanazawa Medical University) date: 2012-05-17 words: 18896 flesch: 49 summary: However, mechanism of recognition of taste receptor cells which express appropriate taste receptor is still unknown. Using calcium imaging and immunocytochemistry, we revealed that ATP activates type II and III taste cells and HCl activates type III taste cells, and also that HCl and ATP activate separate subpopulations of taste cells. keywords: acid; activity; cells; dashi; flavor; food; intake; mice; nerve; odor; olfactory; patients; preference; rats; receptor; responses; results; saliva; sensory; solution; stimulation; stimuli; study; subjects; sucrose; swallowing; system; taste; taste cells; type; umami; water cache: cord-015569-vy49r1zd.txt plain text: cord-015569-vy49r1zd.txt item: #112 of 449 id: cord-015910-d9gxew91 author: Grimble, Robert F. title: The Interaction Between Nutrition and Inflammatory Stress Throughout the Life Cycle date: 2005 words: 15218 flesch: 33 summary: The effect of aging on glucocorticoid sensitivity of pro-inflammatory cytokine production was examined in elderly men, testosterone-treated elderly men, and young controls. There is now a large body of evidence suggesting that the decline in ovarian function with menopause is associated with spontaneous increases in pro-inflammatory cytokine production. keywords: body; cell; concentrations; cytokine; diabetes; disease; effect; et al; factor; gene; gsh; human; il-6; inflammation; influence; insulin; men; necrosis; patients; plasma; production; protein; response; stress; studies; study; subjects; tnf cache: cord-015910-d9gxew91.txt plain text: cord-015910-d9gxew91.txt item: #113 of 449 id: cord-015935-r2wd1yfa author: Sokol, Deborah K. title: The Genetics of Autism date: 2011-02-10 words: 11284 flesch: 39 summary: Advances in autism genetics: On the threshold of a new neurobiology Linkage, association, and geneexpression analyses identify CNTNAP2 as an autism-susceptibility gene Memantine lowers amyloid-beta peptide levels in neuronal cultures and in APP/PS1 transgenic mice Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk Molecular genetic basis of tuberous sclerosis complex: From bench to bedside Peripheral biomarkers in autism: Secreted amyloid precursor protein-alpha as a probable key player in early diagnosis Autism as a strongly genetic disorder: Evidence from a British twin study Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment A major susceptibility locus for specific language impairment is located on 13q21 Molecular Analysis of Fragile X Syndrome Therapeutic implications of the mGluR theory of fragile X mental retardation The mGluR theory of fragile X mental retardation Fragile X-associated tremor/ataxia syndrome in sisters related to X-inactivation Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly Replication of autism linkage: Finemapping peak at 17q21 An autosomal genomic screen for autism An autosomal genomic screen for autism Autistic children and their first degree relatives: Relationships between serotonin and norepinephrine levels and intelligence Autism or atypical autism in maternally but not paternally derived proximal 15q duplication Autism, a brain developmental disorder: Some new pathophysiologic and genetics findings Evidence of brain overgrowth in the first year of life in autism Unusual brain growth patterns in early life in patients with autistic disorder: An MRI study Factor analysis of restricted and repetitive behaviors in autism using the autism diagnostic interview-R Neuron, know thy neighbor Correction of fragile X syndrome in mice Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders Gene expression profiles in a transgenic animal model of fragile X syndrome Autism is not associated with the fragile X syndrome Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments High frequency of neurexin Rather than searching for autism genes, endophenotype investigations search for smaller grouping of genes that contribute to discreet phenotypes (Losh et al., 2008) . keywords: analysis; autism; brain; children; chromosome; disorder; dna; et al; families; gene; genome; individuals; language; linkage; mutation; protein; studies; study; syndrome cache: cord-015935-r2wd1yfa.txt plain text: cord-015935-r2wd1yfa.txt item: #114 of 449 id: cord-016130-5q9ufu28 author: Linday, Linda A. title: Nutritional Supplements and Upper Respiratory Tract Illnesses in Young Children in the United States date: 2010-12-17 words: 11346 flesch: 37 summary: The New York Times Mercury and fish oil supplements; Letter Increased mortality in children with mild vitamin A deficiency Dorland's Illustrated Medical Dictionary Vitamin A and retinoids: an update of biological aspects and clinical applications Vitamin A supplementation: implications for morbidity and mortality in children Vitamin A supplementation in infectious diseases: a meta-analysis Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis A randomized, controlled trial of vitamin A in children with severe measles Vitamin A and retinoids in antiviral responses Vitamin A, infection, and immune function Vitamin A therapy for children with respiratory syncytial virus infection: a multicenter trial in the United States Treatment of respiratory syncytial virus infection with vitamin A: a randomized Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth Dietary vitamin A intake and the risk of mortality among children Dietary vitamin A intake and the incidence of diarrhea and respiratory infection among Sudanese children Dietary vitamin A intake in relation to child growth Vitamin D analogues in insulin-dependent diabetes mellitus and other autoimmune diseases: a therapeutic perspective Comparison of the effects of 1,25-dihydroxyvitamin D3 on T lymphocyte subpopulations This chapter discusses the role of essential fatty acids, vitamins, and trace metals in the pathophysiology of inflammation; reviews our clinical research on the use of a lemon-flavored cod liver oil (which meets European purity standards) and a children's chewable multivitamin-mineral with Se for the prevention and adjunctive treatment of these disorders; reviews the history of cod liver oil, including its importance in the discovery of vitamin D and the anti-infective properties of vitamin A; and discusses the current clinical use of these supplements. keywords: children; cod; cod liver; fatty; fish; group; infections; liver; liver oil; oil; rickets; sinusitis; states; study; supplementation; supplements; treatment; united; use; vitamin cache: cord-016130-5q9ufu28.txt plain text: cord-016130-5q9ufu28.txt item: #115 of 449 id: cord-016472-jj7fqcen author: Freudenberg, Nicholas title: Health Research Behind Bars: A Brief Guide to Research in Jails and Prisons date: 2007 words: 7503 flesch: 27 summary: Funders who have provided significant support to correctional health research include public agencies such as the National Institutes of Drug Abuse, Alcohol Abuse and Alcoholism, Mental Health, and Allergy and Infectious Diseases, the Centers for Disease Control and Prevention, the National Institute of Justice, and some state and local governments. â�¢ What level of individual or population benefits in correctional health research balances potential risks? keywords: health; hiv; incarceration; inmates; jail; justice; officials; populations; prison; public; research; researchers; services; studies; study cache: cord-016472-jj7fqcen.txt plain text: cord-016472-jj7fqcen.txt item: #116 of 449 id: cord-017208-7oew461e author: Aurigemma, Rosemarie title: Regulatory Aspects in the Development of Gene Therapies date: 2005 words: 18332 flesch: 33 summary: S7A safety pharmacology studies for human pharmaceuticals Code of Federal Regulations, Title 21, Food and Drugs, Part 610.10, Subpart B, General biological products standards; general provisions; potency Code of Federal Regulations, Title 21, Food and Drugs, Part 610.12, Subpart B, General biological products standards Code of Federal Regulations, Title 21, Food and Drugs, Part 610.13, Subpart B, General biological products standards Code of Federal Regulations, Title 21, Food and Drugs, Part 610.14, Subpart B, General biological products standards Code of Federal Regulations, Title 21, Food and Drugs, Part 58, Good laboratory practice for nonclinical laboratory studies Current good manufacturing practice in manufacturing, processing, packing, or holding of drugs; general Code of Federal Regulations, Title 21, Food and Drugs, Part 211, Current good manufacturing practice for finished pharmaceuticals Code of Federal Regulations, Title 21, Food and Drugs, Part 312, Investigational new drug application INDs) for phase I studies of drugs, including well-characterized, therapeutic, biotechnology-derived products FDA guidance for industry: IND's for phases 2 and 3 studies of drugs, including specified therapeutic biotechnology-derived products, chemistry, manufacturing and controls content and format FDA guidance for industry: content and format of chemistry, manufacturing, and controls information and establishment description information for a vaccine or related product FDA guidance for industry for the submission of chemistry, manufacturing, and controls information for a therapeutic recombinant DNA-derived product or a monoclonal antibody product for in vivo use FDA guidance for industry: formal meetings with sponsors and applicants for PDUFA products FDA points to consider in the manufacturing and testing of monoclonal antibody products for human use FDA letter to manufacturers of biological products: recommendations regarding bovine spongiform encephalopathy (BSE) FDA Biological Response Modifiers Advisory Committee: current policy on sequence characterization of gene transfer products FDA Biological Response Modifiers Advisory Committee: adenovirus titer measurements and RCA levels FDA guidance for industry: supplemental guidance on testing for replication competent retrovirus in retroviral vector based gene therapy products and during follow-up of patients in clinical trials using retroviral vectors FDA points to consider in the characterization of cell lines used to produce biologicals FDA gene therapy patient tracking system final document FDA guidance concerning demonstration of comparability of human biological products, including therapeutic biotechnology-derived products Third national NIH gene transfer safety symposium: safety considerations in the use of AAV vectors in gene transfer clinical trials Basic principles of gene therapy: basic principles and safety considerations Preclinical animal models in gene therapy research A new animal model for human respiratory tract disease due to adenovirus Use of Aotus monkey to assess neurovirulence of replication-selective herpes vectors Herpes simplex type 1 infects and establishes latency in the brain and trigeminal ganglia during primary infection of the lip in cotton rats and mice Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus Porcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus) As a result, it was only natural that these animals be used to evaluate the safety of gene therapy vectors produced from HSV-1. keywords: adenovirus; administration; agent; animal; assays; cell; cgmp; development; dose; evaluation; fda; gene; gene therapy; human; preclinical; product; production; recombinant; replication; response; safety; studies; therapy; toxicity; transfer; use; vector; virus cache: cord-017208-7oew461e.txt plain text: cord-017208-7oew461e.txt item: #117 of 449 id: cord-017248-a37t31u1 author: None title: Alphabetic Listing of Diseases and Conditions date: 2010-05-17 words: 48773 flesch: 37 summary: Peptic ulcers may be associated with emphysema,* tuberculosis,* and other chronic pulmonary diseases. Procedures See under Alcoholism and alcohol intoxication. keywords: abnormalities; acute; air; alcohol; analysis; aorta; aortic; arteries; artery; atresia; autopsy; blood; body; bone; brain; cases; cause; cell; cerebral; changes; chapter; chronic; column; concentrations; conditions; congenital; coronary; death; defect; deficiency; diagnosis; disease; dissection; embolism; evidence; examination; findings; formalin; gas; hand; heart; histologic; histologic study; infection; lesions; liver; lung; manifestations; material; neck; note; organs; patients; photograph; pneumonia; poisoning; preparation; prepare; present; procedures; pulmonary; record; removal; renal; report; request; right; roentgenograms; samples; sections; skin; specimen; spinal; stain; study; syndrome; synonyms; terms; time; tissue; toxicologic; tumor; type; valve; ventricular; vessels; victim; water; weight cache: cord-017248-a37t31u1.txt plain text: cord-017248-a37t31u1.txt item: #118 of 449 id: cord-017955-oipail5l author: Wilkie, David A. title: The Ophthalmic Examination as It Pertains to General Ocular Toxicology: Basic and Advanced Techniques and Species-Associated Findings date: 2013-08-29 words: 12677 flesch: 44 summary: All personnel, including the consulting ophthalmologist, involved in animal studies will be expected to be familiar with GLP and will usually be required to take annual GLP-refresher courses. This chapter emphasizes the routine ophthalmic examination of laboratory animals. keywords: abnormalities; animals; anterior; corneal; dystrophy; examination; eye; fig; findings; fluorescein; fundus; laboratory; lens; normal; ophthalmologist; rats; slit; species; studies; study cache: cord-017955-oipail5l.txt plain text: cord-017955-oipail5l.txt item: #119 of 449 id: cord-019347-tj3ye1mx author: None title: ABSTRACT BOOK date: 2010-02-19 words: 108161 flesch: 50 summary: in allergic patients and 250 and 500 ug. In allergic patients after histamine threshold challenge mean decrease was for FEV1 19, 2% and for FEV1/VC 17, 3%. keywords: age; airway; allergen; allergic; allergy; allergy asthma; analysis; anti; antibody; asthma; asthma control; asthma diagnosis; asthma patients; asthma symptoms; atopic; background; baseline; blood; care; case; cd4; cells; chest; children; chronic; conclusion; control; daily; data; day; days; deficiency; desensitization; diagnosis; disease; dose; drug; effect; efficacy; evaluation; exposure; female; following; food; function; group; histamine; history; hours; ics; ige; igg; immune; improvement; increase; infections; inflammatory; introduction; levels; life; low; lung; male; mean; medical; medication; methods; minutes; months; nasal; negative; new; non; normal; number; objective; ova; patients; period; persistent; placebo; pollen; population; positive; prednisone; prevalence; prick; primary; production; pulmonary; quality; rate; reactions; recurrent; report; response; results; rhinitis; rhinitis patients; risk; serum; severity; significant; skin; specific; spray; studies; study; subjects; symptoms; syndrome; testing; tests; therapy; time; total; treatment; urticaria; use; visits; weeks; wheezing; years cache: cord-019347-tj3ye1mx.txt plain text: cord-019347-tj3ye1mx.txt item: #120 of 449 id: cord-019490-m1cuuehi author: None title: Abstracts cont. date: 2015-12-28 words: 93719 flesch: 45 summary: Mean age (78 vs 77), Charlson score (2.5 vs. 2.6), neoplasm (22% vs. 21%), HIV (0.7% vs. 0.8%), chronic liver disease (9% vs.7%), diabetes mellitus ( 19% vs.22%), ICU admission (4% vs. 4%), monotherapy (63% vs. 66%), and aetiology (S. pneumoniae 34% vs. 36%; L. pneumophila 3% vs.2%; others 8% vs.11%; unknown 54% vs.51%) were similar. The same was found for mecillinam, i.e. no correlation for AUC/MIC vs. CFÚ s in urine or organs, while Time > MIC % significantly (P < 0.05) correlated with CFÚ s in urine (R 2 = 0.48), and kidney tissue (R 2 = 0.82), respectively. keywords: activity; aeruginosa; agar; agents; aim; analysis; anthrax; antibiotics; antimicrobial; assay; associated; aureus; bacteria; blood; broth; cases; ciprofloxacin; clinical; coli; concentrations; conclusions; control; data; days; detection; diagnosis; disease; dose; drug; effect; erythromycin; gene; gram; grn; group; hospital; hours; human; imipenem; infections; isolates; laboratory; levofloxacin; linezolid; low; mcg; mean; methicillin; methods; mic; mic90; mics; moxifloxacin; mrsa; mrsa strains; nccls; negative; new; non; objectives; oral; pathogens; patients; pcr; penicillin; period; pfge; phenotype; plasma; pneumoniae; population; positive; presence; prevalence; pylori; rates; resistance; results; risk; s. aureus; samples; serum; single; skin; species; spectrum; spp; staphylococcus; strains; studies; study; subjects; susceptibility; susceptible; tested; testing; therapy; tigecycline; time; tissue; total; tract; treatment; type; use; values; vancomycin; vitro; water; years cache: cord-019490-m1cuuehi.txt plain text: cord-019490-m1cuuehi.txt item: #121 of 449 id: cord-020316-xr9h4c1q author: None title: Million women study most wanted in 2003 date: 2004-04-10 words: 224 flesch: 11 summary: Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial Coronavirus as a possible cause of severe acute respiratory syndrome Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial Advances in cystic fibrosis Cystic fibrosis Elusive schizophrenia genes Genes for schizophrenia? Recent findings and their pathophysiological implications Detecting ovarian cancer Use of proteomic patterns in serum to identify ovarian cancer Heart Protection Study Collaborative Group. keywords: study cache: cord-020316-xr9h4c1q.txt plain text: cord-020316-xr9h4c1q.txt item: #122 of 449 id: cord-021206-4zyqqgs0 author: None title: Scientific and Educational Exhibits date: 2007 words: 138880 flesch: 44 summary: Conclusion: In the appropriate clinical setting, CT fi ndings in immunologic lung diseases other than asthma and collagen-vascular disorders are suggestive of the underlying disorders and allow in making the correct diagnosis with a reasonable level of confi dence. CT fi ndings combined with certain histopathologic features can suggest specifi c diagnosis. keywords: abdominal; abnormalities; accuracy; acute; adc; analysis; anatomy; angiography; aortic; approach; arterial; arteries; artery; assessment; associated; background; benign; biopsy; blood; body; bone; bowel; brain; breast; cancer; cancer patients; carcinoma; cardiac; cases; changes; chest; classifi; complications; conclusion; conditions; confi; contrast; coronary; correlation; ct angiography; ct fi; ct images; cta; data; defi; details; detection; diagnosis; diameter; diffusion; disease; doppler; dose; dynamic; echo; enhancement; evaluation; examination; exhibit; fat; fi eld; fi ndings; fi rst; follow; group; heart; high; identifi; images; imaging; imaging features; imaging fi; infl; information; injection; involvement; learning; left; lesions; low; lung; malignant; management; masses; materials; mdct; mean; methods; mr images; mr imaging; mri; mri fi; new; nodes; non; normal; number; objectives; parameters; pathology; patients; pattern; perfusion; pet; phase; post; presence; primary; procedure; protocol; pulmonary; purpose; quality; radiation; radiological; radiologists; rate; renal; resolution; resonance imaging; results; review; right; risk; role; scan; sequences; signal; signifi; size; slice; specifi; spectrum; standard; stenosis; structures; studies; study; surgery; system; technique; test; therapy; thickness; time; tissue; total; treatment; tumors; type; ultrasound; use; value; vascular; venous; volume; wall; years cache: cord-021206-4zyqqgs0.txt plain text: cord-021206-4zyqqgs0.txt item: #123 of 449 id: cord-022082-1dq623oe author: Greaves, Peter title: Respiratory Tract date: 2007-09-28 words: 19712 flesch: 22 summary: ^^^ Plasticembedded sections also show the inclusions in other pulmonary cells including pneumocytes attached to the alveolar walls, from which they can be seen discharging into the alveolar spaces. In contrast to findings in people, squamous cell lung tumours are only occasionally seen arising spontaneously in laboratory animals. keywords: administration; agents; airways; alveolar; animals; bronchial; cells; changes; drug; effects; epithelium; fibrosis; humans; hyperplasia; inhalation; laboratory; laboratory animals; lesions; lung; macrophages; mice; mucosa; nasal; olfactory; pulmonary; rats; respiratory; species; studies; study; tissue; toxicity; tract; type cache: cord-022082-1dq623oe.txt plain text: cord-022082-1dq623oe.txt item: #124 of 449 id: cord-022219-y7vsc6r7 author: PEIFFER, ROBERT L. title: Animals in Ophthalmic Research: Concepts and Methodologies date: 2013-11-17 words: 24877 flesch: 43 summary: Deep inoculations are required to produce a stromal keratitis (Fig. 1) , while the epithelial disease may be induced through shallow scratches (Polli koff et al., 1972) . A discussion of the optical principles of specular mi croscopy is provided by Laing et al. keywords: animals; antigen; aqueous; blood; cataracts; cells; chamber; changes; cornea; culture; disease; dogs; drugs; effects; endothelial; et al; eye; fig; glaucoma; guinea; human; humor; injection; iop; laboratory; lens; lenses; model; monkeys; outflow; pressure; rabbit; rats; research; response; results; retina; species; studies; study; technique; tissue; use; uveitis; vessels cache: cord-022219-y7vsc6r7.txt plain text: cord-022219-y7vsc6r7.txt item: #125 of 449 id: cord-022467-j2trahab author: Loo, May title: Select Populations: Children date: 2009-05-15 words: 19091 flesch: 37 summary: Relationship between breast-feeding duration and acute respiratory infections in infants Cognitive training in ADHD children: less to it than meets the eye Hyperactive children treated with stimulants: is cognitive training a useful adjunct? Efficacy and safety of a fixed-combination homeopathic therapy for sinusitis Clinical assessment of acupuncture in asthma therapy: discussion paper Committee on Drugs: Guidelines for the ethical conduct of studies to evaluate drugs in pediatric populations Committee on Children with Disabilities: Counseling families who choose complementary and alternative medicine for their child with chronic illness or disability Measles-mumps-rubella immunisation, autism, and inflammatory bowel disease: update Evaluation of massage with essential oils on childhood atopic eczema Respiratory syncytial virus vaccines for otitis media The use of alternative therapies by children with asthma: a brief report Use of complementary and alternative medicine in the treatment of asthma Use of complementary treatment by those hospitalised with acute illness Some nontraditional (unconventional and/or innovative) psychosocial treatments for children and adolescents: critique and proposed screening principles Hypnotherapy in the treatment of bronchial asthma International study of asthma and allergies in childhood (ISAAC): rationale and methods Asthma mortality and hospitalization among children and young adults: United States Cranio-sacral therapy and the treatment of common childhood conditions A comparison of active and simulated chiropractic manipulation as adjunctive treatment for childhood asthma Hypnosis and self-hypnosis in the management of nocturnal enuresis: a comparative study with imipramine therapy Spirituality, religion, and pediatrics: intersecting worlds of healing Acupuncture and micro-massage in the treatment of idiopathic nocturnal enuresis Treatment of incontinent boys with non-obstructive disease Academic medicine and complementary medicine differ from each other in reasoning and evaluation but not in goals Alternative and controversial treatments for attention-deficit/hyperactivity disorder Parent acceptability and feasibility of ADHD interventions: assessment, correlates, and predictive validity Management of acute and chronic otitis media in pediatric practice Evaluation of rhesus rotavirus monovalent and tetravalent reassortant vaccines in U.S. children Traditional acupuncture increases the content of beta-endorphin in immune cells and influences mitogen induced proliferation A double-blind placebo-controlled study of desipramine in the treatment of ADD. I. General trends and demographic groups Relationship of infant feeding to recurrent wheezing at age 6 years Current treatment of allergic rhinitis and sinusitis 302 cases of enuresis treated with acupuncture Treatment of acne with ear acupuncture-a clinical observation of 80 cases 14 cases of child bronchial asthma treated by auricular plaster and meridian instrument Acupuncture of guanyuan (Ren 4) and Baihui (Du 20) in the treatment of 500 cases of enuresis Effect of acupuncture on bronchial asthma Acupuncture treatment of chronic rhinitis in 75 cases Immediate antiasthmatic effect of acupuncture in 192 cases of bronchial asthma Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases Clinical and experimental study on yifei jianshen mixture in preventing and treating infantile repetitive respiratory infection Clinical investigation on massage for prevention and treatment of recurrent respiratory tract infection in children Pneumococcal conjugate vaccine for young children Prevention of asthma morbidity: recent advances keywords: acupuncture; acupuncture treatment; acute; age; alternative; asthma; breast; cam; childhood; children; chiropractic; chronic; diarrhea; disease; efficacy; enuresis; group; homeopathic; infants; medicine; months; otitis; patients; pediatric; studies; study; symptoms; therapy; treatment; trial; use; years cache: cord-022467-j2trahab.txt plain text: cord-022467-j2trahab.txt item: #126 of 449 id: cord-022501-9wnmdvg5 author: None title: P1460 – P1884 date: 2015-12-28 words: 128422 flesch: 46 summary: In the first half-year of 2005 family doctors most often prescribed penicyllins -(44.8%), makrolids -(27.1%), cephalosporins -(12.5%), tetracyclins -(9.4%) and lincozamidsbased (3.1%) treatments Specialist doctors, on the other hand, prescribed penicllins (41.7%), makrolids (17.9%), cephalosporins (17.7%), tetracyclins (12.1%), lincozamids (5.2%) and chinolons (3%). State-wide antibiotic consumption in the AC setting during the same time was 12 DID (~85% of total consumption). keywords: acid; activity; acute; aeruginosa; agar; age; agents; aim; analysis; antibiotic; antimicrobial; assay; aureus; bacteria; beta; blood; care; cases; cause; cfu; children; ciprofloxacin; clinical; coli; common; community; concentrations; conclusion; consumption; control; cost; culture; daily; data; days; detection; diagnosis; diarrhoea; differences; different; difficile; disease; distribution; dna; dose; drug; duration; effect; efficacy; erythromycin; factors; faecium; following; frequency; gene; gram; group; guidelines; health; hospital; hours; human; identification; imipenem; incidence; increase; infections; information; isolates; laboratory; level; levofloxacin; linezolid; mean; medical; meningitis; methicillin; methods; mic; mics; model; months; mortality; moxifloxacin; mrsa; n =; negative; new; non; number; objectives; pathogens; patients; pcr; penicillin; period; phenotype; pneumoniae; population; positive; presence; prevalence; protein; range; rates; resistance; respiratory; results; risk; s. aureus; samples; sequence; sequencing; serum; skin; species; specific; specimens; spectrum; spp; standard; staphylococcus; strains; streptococcus; studies; study; subjects; susceptibility; susceptible; test; tetracycline; therapy; tigecycline; time; tissue; total; toxin; tract; treatment; type; use; values; vancomycin; vitro; years cache: cord-022501-9wnmdvg5.txt plain text: cord-022501-9wnmdvg5.txt item: #127 of 449 id: cord-022527-a0x6lws3 author: None title: Eosinophils in Human Disease date: 2012-10-12 words: 56098 flesch: 33 summary: Extending this study, Flood-Page et al. 74 evaluated anti-IL-5 monoclonal antibody treatment in asthma patients by examining its multidose effect on blood and sputum, as well as bone marrow and airway tissue eosinophils. As corticosteroid treatment reduced serum, sputum, and tissue eosinophils, and these reductions were associated with improved asthma symptoms, the eosinophil's place as a primary contributor to asthma appeared further substantiated. keywords: activation; acute; airway; allergen; anti; asthma; blood; blood eosinophils; bone; bronchial; cells; chronic; crs; cytokines; disease; ecp; eoe; eosinophils; epithelial; expression; factor; following; gene; group; growth; human; il-5; infection; infiltration; inflammation; inflammatory; levels; lung; marrow; mbp; nasal; numbers; patients; polyps; presence; present; production; protein; rejection; release; response; role; serum; skin; specific; sputum; sputum eosinophils; stent; studies; study; subjects; symptoms; syndrome; t cells; t h; therapy; tissue; tissue eosinophils; treatment; tumor; virus cache: cord-022527-a0x6lws3.txt plain text: cord-022527-a0x6lws3.txt item: #128 of 449 id: cord-022594-fx044gcd author: Pirko, Istvan title: Demyelinating Disorders of the Central Nervous System date: 2009-05-18 words: 25150 flesch: 43 summary: Not only do several viral and bacterial peptides share structural similarities with MBP, but it has also been demonstrated that these antigens may activate MBP-specific T-cell clones derived from MS patients. Virus has rarely been cultured from CSF of MS patients, but a new strain of HSV (the MS strain) and a new virus (Inoue-Melnick virus) were first isolated from the CSF of MS patients. keywords: acute; adem; brain; cases; clinical; cns; cord; course; criteria; csf; demyelination; diagnosis; disability; disease; dose; evidence; interferon; lesions; matter; mri; ms patients; patients; rate; relapse; relapsing; risk; sclerosis; spinal; studies; study; symptoms; syndrome; treatment; trial; years cache: cord-022594-fx044gcd.txt plain text: cord-022594-fx044gcd.txt item: #129 of 449 id: cord-022633-fr55uod6 author: None title: SAEM Abstracts, Plenary Session date: 2012-04-26 words: 147610 flesch: 49 summary: Objectives: To identify the prevalence of NCS and other EEG abnormalities in ED patients with AMS. Objectives: Test the hypothesis that prior to antibiotic administration, circulating LPS can be detected in the plasma of fewer than 10% of ED patients with severe sepsis. keywords: academic; acute; admission; adult ed; adult patients; age; analysis; arrest; arrest patients; assessment; association; average; background; blood; cardiac; care; cases; center; change; characteristics; chest; children; clinical; cohort; conclusion; confidence; control; cpr; criteria; data; days; department; diagnosis; difference; discharge; disease; ed care; ed patients; ed physicians; ed visits; eds; effect; emergency; emergency department; ems; evaluation; factors; following; group; health; high; hospital; hospital ed; hours; implementation; increase; information; initial; injury; inpatient; intervention; intubation; length; level; los; low; management; mean; median; medical; medicine; methods; minutes; model; months; mortality; n =; non; number; objectives; outcomes; overall; p =; pain; pain patients; participants; pediatric; performance; period; population; post; pre; prehospital; primary; prior; program; protocol; providers; quality; range; rate; regression; research; residency; residents; respectively; results; retrospective; review; risk; sample; score; screening; self; sepsis; setting; shock; standard; students; studies; study; study ed; subjects; survey; survival; system; table; test; testing; time; total; training; trauma patients; treatment; triage; urban; use; years cache: cord-022633-fr55uod6.txt plain text: cord-022633-fr55uod6.txt item: #130 of 449 id: cord-022650-phsr10jp author: None title: Abstracts TPS date: 2018-08-14 words: 119916 flesch: 51 summary: Method: Postal questionnaires were distributed to an unselected group of asthma patients (n = 190). NHR was reported in 71% of asthma patients and 22% in non-asthmatic controls (P < 0.0001), with changes in temperature being the most important inducer of nasal symptoms (74% of asthmatics), followed by strong odours (62%) and cigarette smoke (61%). keywords: adults; age; aim; allergen; allergies; allergy; analysis; anaphylaxis; angioedema; anti; ara; asthma; asthma control; asthma patients; asthma symptoms; asthmatic; atopic; background; blood; case; cells; challenge; children; chronic; clinic; concentration; conclusion; control; control group; correlation; cross; data; days; dermatitis; diagnosis; differences; disease; dose; drug; dust; effect; efficacy; egg; episodes; exposure; extracts; factors; food; food allergy; grass; group; hae; high; history; hospital; hours; house; ige; ige levels; igg; immunotherapy; improvement; increase; levels; life; low; male; mean; median; medical; medication; method; milk; minutes; mite; months; nasal; non; number; p 1; p =; patients; peanut; period; pollen; pollen allergy; population; positive; present; prevalence; prick; protein; questionnaire; rate; reaction; reactivity; reduction; report; respiratory; response; results; rhinitis; rhinitis patients; risk; scit; score; sensitization; serum; severity; sige; skin; skin prick; slit; specific; spt; studies; study; subjects; symptoms; syndrome; test; testing; time; total; treatment; type; urticaria; use; weeks; years cache: cord-022650-phsr10jp.txt plain text: cord-022650-phsr10jp.txt item: #131 of 449 id: cord-022653-qa1uph35 author: None title: Poster Discussion Session PDS date: 2017-08-30 words: 58403 flesch: 49 summary: Out of all maxillary sinuses (n=72) from study patients, 62 (86.11%) were opacified, and only these sinuses were included in further analyses. We studied three groups of subjects: peach allergic patients who received Prup3-enriched-SLIT for 1 year, peach allergic patients non treated, and healthy controls who tolerated peach. keywords: age; aim; allergen; allergic; allergy; analysis; anaphylaxis; anti; associated; asthma; asthma patients; atopic; blood; cases; cells; changes; children; conclusions; control; correlation; data; diagnosis; differences; disease; dose; drug; effect; exposure; expression; food; food allergy; group; hdm; healthy; history; ige; ige levels; immune; immunotherapy; increase; inflammation; introduction; levels; low; mean; methods; mice; milk; months; nasal; non; number; objectives; patients; period; pollen; production; protein; reactions; reactivity; response; results; rhinitis; risk; samples; score; sensitization; serum; skin; slit; specific; studies; study; subjects; symptoms; test; therapy; time; total; treatment; use; years cache: cord-022653-qa1uph35.txt plain text: cord-022653-qa1uph35.txt item: #132 of 449 id: cord-022659-chwk2bs4 author: None title: Abstracts: Poster session date: 2004-10-08 words: 49293 flesch: 47 summary: We conclude that this cingulate activation may reflect the greater involvement of an attentional network (of which the anterior cingulate is a part) in tasks requiring a higher degree of mental work on the part of AD patients. To investigate erythrocyte membrane molecular dynamics in AD patients and age-matched controls, we investigated erythrocyte membrane molecular motion at the surface (fluorescamine), aqueous-hydrocarbon interface (DPPE-ANS), and hydrocarbon core (1219j-AS; PPC-DPH) by steady-state fluorescence anisotropy measurements of 16 probable AD patients (5 males; 11 females) and 20 (1 1 males; 9 females) age-matched controls. keywords: activation; activity; acute; ad patients; age; als; alzheimer; analysis; antibodies; blood; brain; cases; cells; cerebral; changes; chronic; conduction; controls; criteria; csf; data; days; dementia; diagnosis; disease; dose; effects; evidence; examination; factors; findings; function; group; hours; human; improvement; infection; injury; left; lesions; levels; loss; mean; memory; months; motor; mri; muscle; myelin; nerve; neurological; onset; p =; parkinson; patients; pd patients; present; protein; response; results; risk; scale; sclerosis; scores; sensory; serum; severity; specific; spinal; stroke; studies; study; subjects; symptoms; syndrome; test; treatment; type; women; years cache: cord-022659-chwk2bs4.txt plain text: cord-022659-chwk2bs4.txt item: #133 of 449 id: cord-022888-dnsdg04n author: None title: Poster Sessions date: 2009-08-19 words: 189173 flesch: 41 summary: Our aim is to describe how B cell lymphoma cells respond to TGF-b compared to normal peripheral B cells, to create an overview of the different signaling pathways involved, and to characterize the mechanisms behind the loss of sensitivity to TGF-b. Methods: Proliferation assays were performed on 11 different B-cell lymphoma cell lines and normal peripheral B cells to screen for TGF-b-induced effects. Using a CD3 and CD28 activation model system -TLR4 presence on CD4+ cells is found in mouse T cells, human T cells and Jurkat cell lines. keywords: + cells; ability; absence; activity; addition; analysis; antibodies; antibody; antigen; apoptosis; apoptotic; assay; associated; autoimmune; b cells; b t; binding; blood; bone; c mice; cancer cells; capacity; cd4; cd8 +; cd8 cells; cd8 t; cell activation; cell activity; cell culture; cell cycle; cell death; cell development; cell differentiation; cell epitopes; cell function; cell level; cell lines; cell membrane; cell population; cell proliferation; cell receptor; cell responses; cell subsets; cell surface; cell tolerance; cell types; cells cells; changes; chronic; class; clinical; colitis; complex; conclusion; contrast; control; control cells; cross; ctl; cytokine; cytokine production; cytometry; cytotoxic t; data; day; days; dcs; deficient; delta t; dendritic; disease; dna; early; effector cells; effector t; effects; elisa; expansion; experiments; expression; expression levels; factor; family; findings; flow; following; formation; function; gamma; gd cells; gd t; gene; gene expression; group; high; hiv; hla; host; human; ifn; ifng; igg; il-10; il-2; il-4; il-6; immune; immunity; increase; independent; induction; infected; infection; inflammation; inflammatory; inhibition; inkt; interaction; intracellular; levels; lps; macrophages; major; marrow cells; mast cells; mechanisms; membrane; memory t; methods; mhc; mice; model; molecules; monocytes; mouse; mouse t; mrna; murine; negative; neutrophils; new; nkt cells; non; normal; novel; number; objectives; pathway; patients; pcr; peptide; peripheral; plasma cells; play; positive; potential; presence; presentation; primary; production; promoter; protein; protein expression; receptors; regulation; regulatory; release; results; role; secretion; serum; signaling; skin; sle; specific; spleen; stem cells; stimulation; studies; study; surface expression; system; t cells; t em; t h; t helper; t lymphocytes; target cells; tcr; test; th1 cells; time; tissue; tlr; tnf; tolerance; transcription; treatment; tumor cells; type; university; vaccination; vaccine; vg9vd2 t; virus; vitro; vivo; work cache: cord-022888-dnsdg04n.txt plain text: cord-022888-dnsdg04n.txt item: #134 of 449 id: cord-022889-lv6fy6e6 author: Dávalos, Alberto title: Literature review of baseline information on non‐coding RNA (ncRNA) to support the risk assessment of ncRNA‐based genetically modified plants for food and feed date: 2019-08-07 words: 96106 flesch: 44 summary: In a later observational study, Lukasik et al. evaluated plant miRNAs miR-166a, miR-156a, miR-157a, miR-172a and miR-168a and reported the presence of plant miRNAs in human (n=6) breast milk, both in whole milk and exosomes . This HEN1-dependent 2'-Omethylation on the 3' terminal ribose is a Mg2+ dependent methylation mechanism that will ultimately stabilize miRNAs (Abe et al., 2010; Molnar et al., 2007; Yu et al., 2005; Yang et al., 2006) .The keywords: activity; administration; animals; authors; barriers; biological; blood; bodies; breast; cells; cellular; conclusions; conditions; context; contract; degradation; delivery; dietary; document; dsrna; effects; efsa; et al; european food; exogenous; exosomes; expression; food safety; function; gene; human; immune; information; issues; juliano et; key; levels; literature; mammalian; mice; milk; molecules; mouse; mrna; naked; ncrnas; non; oligonucleotides; oral; output; pathway; plant mirnas; plant ncrna; plant rna; plants; plasma; position; prejudice; presence; present; principle; procedure; proteins; publication; review; rice; rights; rnai; role; safety authority; samples; search; section; serum; silencing; sirna; small; specific; srnas; stability; studies; study; subject; synthetic; system; target; task; tender; tender procedure; tissue; total; transparency; transparency principle; uptake; view; vivo; words; zhang et cache: cord-022889-lv6fy6e6.txt plain text: cord-022889-lv6fy6e6.txt item: #135 of 449 id: cord-022940-atbjwpo5 author: None title: Poster Sessions date: 2016-09-07 words: 241687 flesch: 44 summary: Among used cancer cell lines, ERICD was highly expressed and ARID3A had lower expression in U-2OS (osteosarcoma), A-172 (glioblastoma) and A549 (lung cancer). Clear cell renal cell cancer (ccRCC) with metastases has pour prognosis: 5-year survival is about 9%. keywords: a549 cells; acid; activation; activities; activity; activity levels; acute; addition; administration; affinity; agents; aim; albumin; allele; alterations; alternative; amino; analysis; analysis results; animals; ankara; anti; antibodies; antibody; anticancer; antioxidant; apoptosis; applications; approach; assay; association; bacteria; beta; binding; biology; blood; body; bone; brain; breast cancer; cancer cells; cancer group; cancer patients; cancer stem; cancer treatment; cancers; cause; cell cycle; cell death; cell growth; cell lines; cell proliferation; cell survival; cell viability; changes; characterization; chemical; cholesterol; chronic; clinical; coli; colorectal; combination; comparison; complex; complexes; compounds; concentrations; conclusion; conditions; content; control cells; control group; control study; controls; correlation; culture; curcumin; current; cytotoxic; damage; data; day; days; decrease; department; detection; determination; development; diabetes; differences; differentiation; discussion; disease; dna; domain; dose; drug; effects; elevated; elisa; energy; enzyme; enzyme activity; ethanol; experimental; expression analysis; expression levels; expressions; extract; factor; faculty; family; fat; findings; flow; fluorescence; fold; food; formation; free; function; gene expression; genes; genetic; genome; genotype; glucose; glutathione; group; growth; gsh; health; hours; human; immune; increase; inflammation; inflammatory; inhibition; inhibitors; injury; institute; insulin; interaction; intracellular; introduction; invasion; investigation; ischemia; kinase; laboratory; lead; levels; light; like; lipid; liver; low; lung; male; manner; markers; mass; materials; matrix; mcf-7; mda; mda levels; mean; mechanisms; medical; medicine; medium; membrane; metabolism; methods; methylation; mice; microscopy; migration; mirnas; mitochondrial; model; modified; molecular; molecules; mrna; muscle; mutant; mutations; n =; nanoparticles; negative; non; normal; novel; number; obese; obesity; oil; order; oxidative; oxygen; p =; p-02.08.5; parameters; pathway; patients; pcr; peptide; phase; plant; plasma; play; point; polymorphisms; population; potential; presence; present; process; processes; production; products; profile; progression; promoter; properties; prostate; prostate cancer; protective; protein; protein expression; protein levels; purpose; radical; range; rate; rats; reaction; receptor; recombinant; region; regulation; related; relationship; research; resistance; response; results; risk; role; samples; science; scientific; screening; sequence; serum; serum levels; signaling; site; size; sod; species; specific; stability; stage; status; stem cells; strain; stress; structure; studies; study; study group; subjects; surface; survival; synthesis; system; target; technique; temperature; test; tested; therapeutic; therapy; time; tissue; tnf; total; transcription; treatment; treatment group; tumor; tumor cells; turkey; type; university; use; values; vitamin; vitro; water; weight; western; wild; women; work; years cache: cord-022940-atbjwpo5.txt plain text: cord-022940-atbjwpo5.txt item: #136 of 449 id: cord-022955-vy0qgtll author: None title: Proteases date: 2005-06-20 words: 36483 flesch: 40 summary: Specific molecular associations or shared scaffolds between the involved proteases and/or protein inhibitors and defined three-dimensional structures have also been reported. It was used affinity chromatography, electrophoresis, western-blotting, ELISA, determination of proteins activity. keywords: acid; activation; activities; activity; amino; analysis; binding; brain; calcium; cancer; catalytic; cells; cleavage; complex; control; degradation; domain; effect; enzyme; expression; factor; family; form; function; gcpii; gene; growth; human; hydrolysis; inhibition; inhibitors; levels; like; mail; mechanism; membrane; model; molecular; pathway; peptide; presence; present; protease; protease activity; protease inhibitors; protein; proteolysis; regulation; results; role; sequence; serine; serine protease; site; specificity; structure; studies; study; substrate; system; target; terminal; treatment; trypsin; type; ubiquitin; vitro; zymogen cache: cord-022955-vy0qgtll.txt plain text: cord-022955-vy0qgtll.txt item: #137 of 449 id: cord-023017-k6edtg58 author: None title: AASLD Abstracts (pp. 282A–382A) date: 2006-02-10 words: 65964 flesch: 47 summary: The aim of the present study was to investigate if the same inhibition takes place in livers cells of patients with chronic hepatitis C. From February 2001 to April 2002, all patients with chronic hepatitis C referred to the outpatient liver clinic of the University Hospital Basel were asked for their permission to use part of the liver biopsy for this study. Increased T cell activation with Eta may also suggest that TNFA suppress T cell function and may contribute to refractoriness to INF therapy in HCV patients. keywords: -no; activation; activity; addition; age; alpha; alt; analysis; anti; biopsies; biopsy; blood; cases; cd8; cells; chronic; chronic hcv; chronic hepatitis; cirrhosis; combination; conclusions; control; core; culture; data; days; dcs; different; disease; dose; effect; expression; factors; fibrosis; gene; genotype; group; hcc; hcv; hcv genotype; hcv infection; hcv patients; hcv rna; hepatic; hepatitis; hepatocytes; hsc; human; ifn; infection; interferon; levels; liver; mean; meld; methods; mice; months; negative; non; ns3; patients; pcr; population; positive; protein; rats; rejection; relationships; response; results; ribavirin; risk; role; serum; specific; steatosis; stem; studies; study; subjects; survival; system; t cells; therapy; time; total; transplantation; treated; treatment; virus; weeks; years cache: cord-023017-k6edtg58.txt plain text: cord-023017-k6edtg58.txt item: #138 of 449 id: cord-023026-2r84ndzv author: None title: Posters date: 2013-06-14 words: 138804 flesch: 38 summary: Levels of expression of NG2 mRNA and protein in mouse glial cells are regulated by the neurotransmitter glutamate and overexpression of cleaved fragments modulates protein expression in murine glial cells. Interestingly, when we analyzed the in vitro expression pattern of rCD300f in brain cells by Q-PCR and immunohistochemistry, in addition to the expected expression in microglial cells, we detected expression of CD300f in oligodendrocytes and neurons. keywords: activation; activity; acute; addition; adult; analysis; animals; anti; astrocytes; astroglial; axons; blood; brain; brain cells; brain injury; cells; cerebral; changes; chronic; cns; conditions; contrast; control; cord; cortex; cortical; cultures; cytokines; damage; data; days; death; decrease; derived; development; differentiation; disease; eae; effect; evidence; experiments; expression; expression levels; extracellular; factors; findings; formation; function; gene; gene expression; gfap; glial; glucose; glutamate; hippocampal; human; imaging; immune; increase; inflammation; inflammatory; inhibition; injection; injury; ischemic; ko mice; lactate; lesions; levels; loss; lps; macrophages; markers; mechanisms; membrane; metabolic; methods; mice; microglia; microglia activation; microglia cells; migration; model; molecules; morphology; mouse; mrna; myelin; nerve; neural; neurons; new; ng2 cells; non; number; oligodendrocytes; opcs; order; pathway; patients; pcr; phenotype; play; post; potential; precursor cells; presence; present; primary; processes; production; progenitor cells; progression; proliferation; properties; protein; protein expression; rats; receptors; reduced; regulation; release; remyelination; response; results; role; schwann cells; signaling; slices; spinal; stem cells; stress; studies; study; surface; survival; synaptic; system; test; therapeutic; time; tissue; transgenic; treatment; type; uptake; vitro; vivo; weeks cache: cord-023026-2r84ndzv.txt plain text: cord-023026-2r84ndzv.txt item: #139 of 449 id: cord-023049-fio7cjj5 author: None title: 2017 Peripheral Nerve Society Meeting July 8–12, 2017 Sitges, Barcelona, Spain date: 2017-06-22 words: 145714 flesch: 46 summary: We compared the median SNAP with radial SNAP measured antidromically at digit 1 in GBS patients whose nerve conduction study showed the sural-sparing pattern. The aim of the present investigation is to summarize the current knowledge on sweating disturbances in GBS patients. keywords: 1,2; activity; acute; addition; age; aim; amyloid; analysis; anti; antibodies; antibody; associated; axonal; axons; barré; baseline; biopsy; blood; cases; cause; cells; center; changes; charcot; children; chronic; cidp patients; cmt patients; cmt1a; cohort; conduction study; control patients; controls; course; criteria; data; days; degeneration; demyelinating; department; development; diabetic; diagnosis; differences; disability; disease; dominant; dose; effect; examination; expression; f 1; family; findings; following; foot; france; function; g 1; gbs patients; gene; group; guillain; healthy; hospital; human; igg; impairment; improvement; increase; inflammatory; injury; institute; intravenous; involvement; ivig; j 1; k 1; levels; limbs; loss; mag; marie; mean; measures; median; medical; medicine; mice; model; months; motor; motor nerve; mouse; mri; muscle; mutations; ncs; negative; nerve; nerve conduction; nerve fibers; nerve injury; nerve regeneration; neurological; neurology; neurons; neuropathies; neuropathy; new; nf155; non; normal; novel; number; onset; outcome; pain; participants; patients; phenotype; placebo; pmp22; polyneuropathy; positive; potential; present; progression; protein; range; reduced; report; respectively; response; results; risk; role; scale; schwann; score; sensory; sequencing; serum; severe; severity; skin; strength; studies; study; subjects; sural; symptoms; syndrome; system; test; testing; therapeutic; therapy; time; tissue; tooth; total; treatment; ttr; type; ulnar; university; upper; usa; variants; weakness; weeks; y 1; years cache: cord-023049-fio7cjj5.txt plain text: cord-023049-fio7cjj5.txt item: #140 of 449 id: cord-023095-4dannjjm author: None title: Research Abstract Program of the 2011 ACVIM Forum Denver, Colorado, June 15–18, 2011 date: 2011-05-03 words: 134382 flesch: 49 summary: Mminimum HR, mean HR and the HRV variables (7 and 10) differing between dog groups, also consistently decreased with increasing MR, LA/Ao and the proximal isovelocity surface area in CKCS. The apparently normal levels of hexosaminidase A activity in affected dog samples may be a result of b subunit overexpression. keywords: abnormalities; acid; acth; activity; administration; adult; age; aim; analysis; animals; assay; association; available; baseline; blood; blood samples; body; breed dogs; breeds; canine; cardiac; cases; cats; cell; changes; chf; chronic; clinical; cobalamin; compare; concentrations; control dogs; controls; correlation; cortisol; creatinine; data; days; decrease; detection; diagnosis; diet; difference; disease; dna; dogs; dose; drug; duration; effects; elisa; equine; evidence; examination; expression; failure; fecal; feline; findings; foals; following; food; function; gastrointestinal; gene; glucose; group; heart; horses; hours; human; increase; infection; insulin; isolates; levels; mean; median; medical; minutes; model; months; negative; non; number; observed; outcome; p o; parameters; patients; pcr; period; plasma; platelet; post; potential; presence; present; prevalence; protein; pulmonary; purpose; range; rate; reference; resistance; response; results; risk; role; samples; serum; serum concentrations; serum samples; severity; significance; signs; species; specific; spinal; spp; standard; studies; study; survival; test; therapy; time; tissue; total; treatment; type; urinary; urine; uroliths; use; values; veterinary; weeks; weight; years cache: cord-023095-4dannjjm.txt plain text: cord-023095-4dannjjm.txt item: #141 of 449 id: cord-023134-y665agnh author: None title: Oral Research Communications of the 22(nd) ECVIM‐CA Congress date: 2012-11-20 words: 29627 flesch: 47 summary: Concerning gross pathology findings in hearts with clinical DCM diagnosis, LV chambers were dilated in 3/4 cases of group 4, while in groups 3 and 5, the papillary muscles appeared grossly prominent and not flattened as in group 4.Histopathologically, in control dogs LV and RV myocardium showed no (3/4) or mild (1/4) interstitial collagen deposits, no or single adipocytes, and normal vessels. Histopathologically, RAA in control dogs showed small amounts of interstitialcollagen and single adipocytes. keywords: acth; analysis; animals; baseline; bem; blood; canine; cases; cats; concentrations; control; cortisol; dcm; diagnosis; disease; dogs; expression; feline; function; gene; group; heart; high; human; ibd; insulin; mean; median; parameters; plasma; post; pressure; range; results; samples; serum; studies; study; test; time; treatment; values; ventricular cache: cord-023134-y665agnh.txt plain text: cord-023134-y665agnh.txt item: #142 of 449 id: cord-023157-0lqlx2rv author: None title: Poster Sessions date: 2013-04-18 words: 128609 flesch: 50 summary: Results: Mean values of WC, blood pressure (BP), fasting plasma glucose (FPG), triglycerides (TG), HDL-Cholesterol and BMI were significantly higher in men than in women who had higher %BF (28% vs. 21%). Results: During IvGTT GBP-pigs displayed lower glucose and higher insulin levels compared to controls. keywords: 0.001; acid; activity; adiponectin; adipose; age; aim; analysis; association; background; baseline; blood; blood glucose; blood pressure; bmi; body; body weight; cardiovascular; changes; children; cholesterol; circumference; clinical; conclusion; control; control group; correlation; criteria; crp; data; day; decrease; development; diabetes; diabetes mellitus; diet; disease; dm patients; effect; expression; factors; fasting; fat; females; gene; glucose; glucose levels; glucose tolerance; group; hba1c; hdl; health; homa; hypertension; increase; index; individuals; insulin; insulin levels; insulin resistance; insulin sensitivity; intake; leptin; levels; lipid; liver; low; markers; mass; mean; metabolic; methods; mets; mice; mmol; model; months; n =; non; normal; obese; obesity; objective; overweight; oxidative; p =; parameters; participants; patients; plasma; plasma glucose; population; pressure; prevalence; profile; protein; r =; rate; ratio; rats; reduction; results; risk; risk factors; role; sensitivity; serum; stress; study; study group; subjects; syndrome; test; time; tissue; total; treatment; triglycerides; type; university; values; vs.; waist; weeks; weight; women; years cache: cord-023157-0lqlx2rv.txt plain text: cord-023157-0lqlx2rv.txt item: #143 of 449 id: cord-023186-gqltd6u0 author: None title: Poster Sessions date: 2019-06-27 words: 14394 flesch: 52 summary: In addition, the group with a negative slope of FEV1% predicted change during the first 3 months had a higher likelihood of O2 therapy, compared to the group with a positive slope of FEV1 change during the period (HR of 3.57, P = 0.059). However, there was no significant difference in the change over 3 months of FEV1% predicted values between the two groups at 6, 9, and 12 months. keywords: age; asthma; cases; children; days; difference; flow; group; hospital; infants; lung; months; oxygen; patients; pneumonia; rate; results; score; stay; study; therapy; total; treatment; years cache: cord-023186-gqltd6u0.txt plain text: cord-023186-gqltd6u0.txt item: #144 of 449 id: cord-023208-w99gc5nx author: None title: Poster Presentation Abstracts date: 2006-09-01 words: 71178 flesch: 41 summary: Peptide structures can be approached by spectroscopy and NMR techniques but data from these approaches too frequently diverge. To increase the stability and the therapeutic efficacy of peptide sequences from myelin oligodendrocyte protein (MOG) that act as multiple sclerosis (MS) antigens, we grafted them onto a framework of a particularly stable class of peptides, the cyclotides. keywords: acid; activation; activity; affinity; aggregation; aim; alpha; amino; amino acid; analogues; analysis; approach; arg; assay; beta; binding; blood; bond; cancer; cell; chain; chemical; chemistry; complex; complexes; compounds; concentration; conformational; conjugates; cyclic; data; derivatives; design; development; disulfide; dna; domain; effect; enzyme; epitope; fmoc; fragment; gly; group; growth; hplc; human; inhibitors; integrin; interaction; ligands; mechanism; membrane; method; mice; model; molecular; molecules; native; new; nmr; non; novel; opioid; order; patients; peptide; peptide analogues; peptide chain; peptide synthesis; phase; phase peptide; phe; position; potential; prepared; presence; products; proline; properties; protein; reaction; receptor; residues; results; role; sequence; site; solution; specific; spectroscopy; stability; strategy; structure; studies; study; surface; synthetic; system; target; terminal; therapeutic; treatment; tumor; turn; type; tyr; use; vivo; water; work cache: cord-023208-w99gc5nx.txt plain text: cord-023208-w99gc5nx.txt item: #145 of 449 id: cord-023209-un2ysc2v author: None title: Poster Presentations date: 2008-10-07 words: 112272 flesch: 42 summary: A specifi c bioassay was developed for screening peptides activity in high salinity conditions in order to evaluate the inhibition of biofi lm growth, based on growing biofi lmforming bacteria in a 96-wells microtiter plate. The insight into the molecular mechanism of peptides activity is obtained in vitro using SAXS method and artifi cial systems mimicking a bacterial cytoplasmic membrane. keywords: acid peptide; acid residues; acids; activation; activities; activity; affi; agents; aggregation; aim; ala; amide; amino; amino acid; amyloid; analogs; analogues; analysis; antimicrobial; application; approach; assay; backbone; binding; biological; blood; bond; brain; c peptide; cancer; cation; cell; chemical; chemistry; cient; city; coil; complex; compounds; concentration; conditions; confi; conformational; conjugates; coupling; cyclic; data; delivery; derivatives; design; development; diseases; dna; domain; drug; ed peptides; effect; effi; experiments; family; fmoc; formation; fragments; free; function; gly; group; helix; hplc; human; identifi; infl; inhibition; inhibitors; interaction; interest; leu; ligation; lipid; mass; mechanism; membrane; method; microwave; model; model peptides; modifi; modifi ed; molecules; native; natural; new; nity; nmr; non; novel; number; order; peptide; peptide analogues; peptide bond; peptide chain; peptide chemistry; peptide fragments; peptide library; peptide ligands; peptide sequence; peptide structure; peptide synthesis; phase peptide; phase synthesis; phe; position; positive; potential; presence; present; process; processes; properties; protein; purifi; range; reaction; receptor; recognition; region; report; residues; results; role; rst; selective; sequence; signifi; site; solution; specifi c; spectroscopy; stability; stable; strategy; structure; studies; study; surface; synthetic; system; target; terminal; terminus; therapy; time; treatment; trp; tumor; type; university; uorescence; uptake; use; vitro; vivo; water; work cache: cord-023209-un2ysc2v.txt plain text: cord-023209-un2ysc2v.txt item: #146 of 449 id: cord-023211-kt5gt26t author: None title: Poster Session Abstracts date: 2007-08-29 words: 221712 flesch: 48 summary: Understanding how its modulation modifies transepithelial transport and inflammation in CF versus non CF cells should give new therapeutic clues to reduce exaggerated inflammation and improve fluid secretion in CF patients. This finding indicates that CFTR potentiators have a wide efficacy on many class III mutants and therefore may represent a promising therapeutic strategy for a significant number of CF patients. keywords: acid; addition; adult cf; adult patients; adults; aeruginosa; age; aim; airway; airway cells; amiloride; analysis; antibiotic; asl; assay; atp; background; bacterial; baseline; binding; biofilm; blood; bmi; cells; cf airways; cf care; cf center; cf clinic; cf foundation; cf gene; cf group; cf lung; cf mouse; cf nbs; cf patients; cf research; cf sputum; cff; cfrd; cftr; cftr activation; cftr activity; cftr cells; cftr channel; cftr chloride; cftr expression; cftr function; cftr gene; cftr inhibitor; cftr mice; cftr mutations; cftr promoter; cftr protein; cftr trafficking; changes; channel; children; chronic; clearance; clinical; concentrations; conclusion; conditions; contrast; control; cultures; current; cystic; daily; data; day; days; decline; decreased; dependent; diabetes; differences; disease; dna; domain; dose; drug; effect; enac; epithelial; exacerbation; experiments; exposure; expressing; f508del; factors; family; fev1; fibrosis patients; findings; fold; forskolin; functional; genes; glands; group; growth; health; hospital; hours; human; human cf; il-8; improvement; increase; individuals; infants; infection; inflammation; inflammatory; information; inhibited; inhibition; isolates; levels; life; low; lung cells; lung disease; lung function; lungs; mean; measure; mechanism; median; medical; membrane; methods; mice; model; months; mrsa; mucus; mutant; nasal; nbd1; neutrophil; new; non; normal; novel; number; observed; order; pancreatic; parents; pathway; patients age; pcr; pediatric; period; plasma; population; positive; post; potential; presence; present; production; proteins; pseudomonas; pulmonary; quality; range; rate; regulation; research; respiratory; response; results; risk; role; samples; scores; screening; secretion; sensitive; serum; specific; status; stimulation; strains; studies; study; study patients; subjects; support; surface; symptoms; system; test; testing; therapeutic; therapies; therapy; time; tobramycin; total; transport; treatment; type cftr; university; usa; use; values; vitamin; vitro; vivo; volume; weight; wt cells; wt cftr; years; ∆f508 cftr cache: cord-023211-kt5gt26t.txt plain text: cord-023211-kt5gt26t.txt item: #147 of 449 id: cord-023216-avn8f2w3 author: None title: Symposium summaries date: 2004-10-18 words: 55740 flesch: 41 summary: The existence of an underlying defect in the airway immune response of CF patients remains controversial; however, increasing evidence suggests that the CF lung exhibits an exaggerated immune response even in the absence of bacterial infection (1;2). In CF patients with mild disease, compared with age-matched normal subjects, a reduced mucociliary clearance has been reported (4). keywords: activity; age; airway; analysis; atp; binding; bone; care; cells; center; cf care; cf lung; cftr; cftr function; cftr protein; channel; children; chloride; chronic; clearance; control; cystic; data; diabetes; diagnosis; disease; early; expression; factors; fibrosis; function; gene; genetic; glucose; human; infection; inflammation; insulin; kinase; levels; life; liver; liver disease; lung; lung disease; mice; mucus; mutations; newborn; non; pain; patients; potential; protein; respiratory; response; results; role; screening; secretion; specific; studies; study; surface; sweat; therapy; time; transport; treatment; type; use; years cache: cord-023216-avn8f2w3.txt plain text: cord-023216-avn8f2w3.txt item: #148 of 449 id: cord-023225-5quigar4 author: None title: Posters date: 2012-08-21 words: 70555 flesch: 41 summary: Aim of this study is the introduction, in the type 1' β turn peptide structure, of the sugar moiety specific for anti-gangliosides antibody recognition by synthesizing specific building blocks. Peptide synthesis was used to verify the accuracy of the determined sequence and to prepare sufficient peptide amount for biological activity studies. keywords: acid; activity; addition; affinity; agents; aggregation; aib; aim; amino; amino acid; amyloid; analogs; analogues; analysis; approach; bacteria; binding; biological; blood; bond; cancer; cell; chain; chemical; chemistry; class; complex; compounds; conditions; conformation; cyclic; cys; data; derivatives; design; development; disease; disulfide; dna; drug; effect; fmoc; formation; function; gly; group; helical; helix; human; hydrophobic; increase; inhibitor; interactions; leu; linear; mechanism; membrane; method; model; moiety; molecules; new; nmr; non; novel; order; peptide; peptide analogues; peptide sequence; peptide synthesis; phase; phase peptide; phe; position; potential; presence; present; process; properties; protein; reaction; receptor; residues; resin; results; role; selective; selectivity; sequence; series; site; solution; specific; specificity; stability; strategy; structure; studies; study; synthetic; system; target; terminal; terminus; treatment; type; university; use; vivo; water; work cache: cord-023225-5quigar4.txt plain text: cord-023225-5quigar4.txt item: #149 of 449 id: cord-023239-06a03o14 author: None title: II. Topic Sessions date: 2016-06-10 words: 33484 flesch: 34 summary: Several studies reported an association of preterm birth (30-36 weeks' GA) without clinical lung disease with altered lung development and function [2] . The Size and Lung function In Children (SLIC) study was designed to improve normative reference ranges for lung function by taking differences in body physique into account to facilitate early diagnosis and treatment of lung disease in all children, irrespective of ethnic background 7 . keywords: age; airway; approach; asthma; birth; bronchiectasis; cells; cftr; childhood; children; chronic; control; cystic; data; diagnosis; disease; effect; evidence; exacerbations; factors; fibrosis; function; infants; lung; lung disease; lung function; need; non; osas; patients; pcd; pneumonia; preschool; preterm; receptors; respiratory; results; risk; sleep; studies; study; symptoms; term; therapy; treatment; use; years cache: cord-023239-06a03o14.txt plain text: cord-023239-06a03o14.txt item: #150 of 449 id: cord-023288-sqr33y72 author: None title: Paediatric SIG: Poster Session date: 2008-03-12 words: 30188 flesch: 50 summary: Conclusions This is the first Australian study to identify alexithymia among asthma patients and investigate relationship to control as well as management and communication. Methods Cross sectional study of 25 moderate to severe asthma patients recruited from Royal Adelaide Hospital Outpatients. keywords: age; aim; airway; analysis; asm; asthma; asthmatics; blood; cancer; cells; children; conclusions; control; copd; data; days; disease; effect; expression; fev1; flow; function; group; health; il-6; increase; infection; inflammatory; levels; lung; mean; methods; mice; n =; non; p =; participants; patients; pulmonary; response; results; risk; smokers; study; subjects; therapy; treatment; use; years cache: cord-023288-sqr33y72.txt plain text: cord-023288-sqr33y72.txt item: #151 of 449 id: cord-023298-ysur3sjq author: None title: Respiratory Nurses SIG: Poster Session date: 2011-03-21 words: 32066 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023298-ysur3sjq.txt plain text: cord-023298-ysur3sjq.txt item: #152 of 449 id: cord-023302-p9pxz44a author: None title: Cystic Fibrosis SIG: Poster Session date: 2011-03-21 words: 32066 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023302-p9pxz44a.txt plain text: cord-023302-p9pxz44a.txt item: #153 of 449 id: cord-023303-fxus38mp author: None title: Lung Cancer/Bronchology SIGs: Combined Poster Session date: 2008-03-12 words: 30191 flesch: 50 summary: Conclusions This is the first Australian study to identify alexithymia among asthma patients and investigate relationship to control as well as management and communication. Methods Cross sectional study of 25 moderate to severe asthma patients recruited from Royal Adelaide Hospital Outpatients. keywords: age; aim; airway; analysis; asm; asthma; asthmatics; blood; cancer; cells; children; conclusions; control; copd; data; days; disease; effect; expression; fev1; flow; function; group; health; il-6; increase; infection; inflammatory; levels; lung; mean; methods; mice; n =; non; p =; participants; patients; pulmonary; response; results; risk; smokers; study; subjects; therapy; treatment; use; years cache: cord-023303-fxus38mp.txt plain text: cord-023303-fxus38mp.txt item: #154 of 449 id: cord-023305-5lb9kho6 author: None title: Oliv SIG: Poster Session date: 2011-03-21 words: 32065 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023305-5lb9kho6.txt plain text: cord-023305-5lb9kho6.txt item: #155 of 449 id: cord-023308-af5nihyi author: None title: COPD SIG: Poster Session 2 date: 2008-03-12 words: 30189 flesch: 50 summary: Conclusions This is the first Australian study to identify alexithymia among asthma patients and investigate relationship to control as well as management and communication. Methods Cross sectional study of 25 moderate to severe asthma patients recruited from Royal Adelaide Hospital Outpatients. keywords: age; aim; airway; analysis; asm; asthma; asthmatics; blood; cancer; cells; children; conclusions; control; copd; data; days; disease; effect; expression; fev1; flow; function; group; health; il-6; increase; infection; inflammatory; levels; lung; mean; methods; mice; n =; non; p =; participants; patients; pulmonary; response; results; risk; smokers; study; subjects; therapy; treatment; use; years cache: cord-023308-af5nihyi.txt plain text: cord-023308-af5nihyi.txt item: #156 of 449 id: cord-023311-7wqdlha4 author: None title: Oral Session date: 2010-11-24 words: 17283 flesch: 47 summary: Conclusion Depression and anxiety were also found in lung cancer patients and need further evaluation and attention from clinician. Methods Patients with medically inoperable or unresectable single nodule NSCLC underwent treatments, in 3 different centers of Bangladesh. keywords: age; airway; asthma; children; conclusion; copd; data; day; diagnosis; disease; group; hospital; infl; introduction; lung; mean; methods; months; mortality; patients; pneumonia; pulmonary; respiratory; results; signifi; sputum; study; total; treatment; tuberculosis; years cache: cord-023311-7wqdlha4.txt plain text: cord-023311-7wqdlha4.txt item: #157 of 449 id: cord-023314-rwjxk8v4 author: None title: Asthma & Allergy SIG: Poster Session 1 date: 2011-03-21 words: 32067 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023314-rwjxk8v4.txt plain text: cord-023314-rwjxk8v4.txt item: #158 of 449 id: cord-023331-jrvmgnu3 author: None title: Asthma & Allergy SIG: Poster Session 3. Physiology, Environment, Investigation and Management date: 2008-03-12 words: 30195 flesch: 50 summary: Conclusions This is the first Australian study to identify alexithymia among asthma patients and investigate relationship to control as well as management and communication. Methods Cross sectional study of 25 moderate to severe asthma patients recruited from Royal Adelaide Hospital Outpatients. keywords: age; aim; airway; analysis; asm; asthma; asthmatics; blood; cancer; cells; children; conclusions; control; copd; data; days; disease; effect; expression; fev1; flow; function; group; health; il-6; increase; infection; inflammatory; levels; lung; mean; methods; mice; n =; non; p =; participants; patients; pulmonary; response; results; risk; smokers; study; subjects; therapy; treatment; use; years cache: cord-023331-jrvmgnu3.txt plain text: cord-023331-jrvmgnu3.txt item: #159 of 449 id: cord-023333-b7w9zrl6 author: None title: Oeld/Population Health SIG: Poster Session date: 2011-03-21 words: 32067 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023333-b7w9zrl6.txt plain text: cord-023333-b7w9zrl6.txt item: #160 of 449 id: cord-023343-y17z9w2x author: None title: COPD SIG: Poster Session 1 date: 2011-03-21 words: 32066 flesch: 52 summary: Results mRNA stability studies indicated that B 1 R SV was ≈35% less stable than the WT transcript in H2126 cells suggesting a stabilizing element 5'UTR. Lower fi bre intake in asthmatic subjects (n = 124) was associated with lower %predicted FEV 1 (r = 0.41, p = 0.004), %FVC (r = 0.43, p = 0.015) and FEV 1 /FVC keywords: acute; age; aim; airway; asm; asthma; cells; children; conclusions; confl; control; copd; cough; data; days; disease; expression; function; group; hospital; hrv; ict; identifi; infection; infl; interest; levels; lung; mean; methods; months; n =; non; p =; patients; post; pulmonary; range; respiratory; results; signifi; studies; study; subjects; symptoms; time; treatment; use; years cache: cord-023343-y17z9w2x.txt plain text: cord-023343-y17z9w2x.txt item: #161 of 449 id: cord-023346-8sqbqjm1 author: None title: MONDAY: POSTERS date: 2005-06-08 words: 130150 flesch: 50 summary: The Polish Blood Transfusion Act of 22nd August 1997, in force since January 1st 1999, has been supplemented by 8 Decrees: 1. procedures for external BTS audits; 2. requirements for donor selection; 3. requirements and procedures for organization and safe management of blood transfusion in hospitals; 4. requirements for implementing of national and regional donor registers; 5. employment criteria for BTS personnel; 6. training requirements for hospital personnel involved in blood and blood product administration; 7. national, uniform price list for blood and blood products; 8. organization requirements for setting up of a National Committee for Blood and Blood Transfusion. Introduction: TRALI is a life threatening adverse reaction of blood transfusion. keywords: aim; analysis; anti; antibodies; antibody; antigens; apheresis; assay; associated; background; blood banking; blood banks; blood cells; blood center; blood collection; blood components; blood donation; blood donors; blood establishments; blood group; blood loss; blood plasma; blood pressure; blood products; blood safety; blood samples; blood service; blood supply; blood system; blood transfusion; blood units; blood volume; cases; clinical; complications; concentrates; conclusion; control; cord blood; count; data; day; days; detection; disease; dna; donations; effect; events; factor; ffp; following; frequency; general; groups; hbsag; hbv; hcv; health; high; hla; hospital; hospital blood; identification; important; increase; infections; information; introduction; iron; laboratory; level; low; major; management; mean; medical; methods; national; negative; new; non; number; order; patients; pcr; period; plasma; platelet; platelet transfusion; population; positive; post; practice; presence; present; procedure; process; quality; range; rbc; rbc transfusion; rbcs; red; results; rhd; risk; routine; screening; serum; specific; standard; storage; studies; study; surgery; system; table; test; tested; testing; therapy; time blood; total; transfusion medicine; transfusion reactions; transfusion service; transfusion therapy; transfusions; treatment; type; use; weak; women; years cache: cord-023346-8sqbqjm1.txt plain text: cord-023346-8sqbqjm1.txt item: #162 of 449 id: cord-023353-2yoz1t6a author: None title: ABSTRACTS FROM THE 2010 EVDI ANNUAL MEETING date: 2010-12-28 words: 30187 flesch: 45 summary: In two buffaloes affected by amelia of the pelvic limbs, CT study of the pelvis was also made. Introduction/Purpose: Ultrasound examination performed by and experience sonographer is becoming the elective exam when suspecting of a gastrointestinal obstruction, replacing contrast radiographic studies for confirmation of these. keywords: anatomy; animals; blood; bone; cases; cats; caudal; changes; clinical; conclusion; contrast; diagnosis; discussion; disease; dogs; doppler; examination; findings; group; horses; images; imaging; introduction; lesions; lung; materials; mean; measurements; methods; mri; purpose; radiographic; renal; results; signs; small; study; thickness; thoracic; time; tumor; ultrasonographic; ultrasound; values; veterinary cache: cord-023353-2yoz1t6a.txt plain text: cord-023353-2yoz1t6a.txt item: #163 of 449 id: cord-023354-f2ciho6o author: None title: TUESDAY PLENARY SESSION 3 TUESDAY: POSTERS date: 2005-06-08 words: 130154 flesch: 50 summary: The Polish Blood Transfusion Act of 22nd August 1997, in force since January 1st 1999, has been supplemented by 8 Decrees: 1. procedures for external BTS audits; 2. requirements for donor selection; 3. requirements and procedures for organization and safe management of blood transfusion in hospitals; 4. requirements for implementing of national and regional donor registers; 5. employment criteria for BTS personnel; 6. training requirements for hospital personnel involved in blood and blood product administration; 7. national, uniform price list for blood and blood products; 8. organization requirements for setting up of a National Committee for Blood and Blood Transfusion. Introduction: TRALI is a life threatening adverse reaction of blood transfusion. keywords: aim; analysis; anti; antibodies; antibody; antigens; apheresis; assay; associated; background; blood banking; blood banks; blood cells; blood center; blood collection; blood components; blood donation; blood donors; blood establishments; blood group; blood loss; blood plasma; blood pressure; blood products; blood safety; blood samples; blood service; blood supply; blood system; blood transfusion; blood units; blood volume; cases; clinical; complications; concentrates; conclusion; control; cord blood; count; data; day; days; detection; disease; dna; donations; effect; events; factor; ffp; following; frequency; general; groups; hbsag; hbv; hcv; health; high; hla; hospital; hospital blood; identification; important; increase; infections; information; introduction; iron; laboratory; level; low; major; management; mean; medical; methods; national; negative; new; non; number; order; patients; pcr; period; plasma; platelet; platelet transfusion; population; positive; post; practice; presence; present; procedure; process; quality; range; rbc; rbc transfusion; rbcs; red; results; rhd; risk; routine; screening; serum; specific; standard; storage; studies; study; surgery; system; table; test; tested; testing; therapy; time blood; total; transfusion medicine; transfusion reactions; transfusion service; transfusion therapy; transfusions; treatment; type; use; weak; women; years cache: cord-023354-f2ciho6o.txt plain text: cord-023354-f2ciho6o.txt item: #164 of 449 id: cord-023364-ut56gczm author: None title: EDUCATION DAY MONDAY: PLENARY SESSION 1 MONDAY: PARALLEL SESSIONS date: 2005-06-08 words: 130157 flesch: 50 summary: The Polish Blood Transfusion Act of 22nd August 1997, in force since January 1st 1999, has been supplemented by 8 Decrees: 1. procedures for external BTS audits; 2. requirements for donor selection; 3. requirements and procedures for organization and safe management of blood transfusion in hospitals; 4. requirements for implementing of national and regional donor registers; 5. employment criteria for BTS personnel; 6. training requirements for hospital personnel involved in blood and blood product administration; 7. national, uniform price list for blood and blood products; 8. organization requirements for setting up of a National Committee for Blood and Blood Transfusion. Introduction: TRALI is a life threatening adverse reaction of blood transfusion. keywords: aim; analysis; anti; antibodies; antibody; antigens; apheresis; assay; associated; background; blood banking; blood banks; blood cells; blood center; blood collection; blood components; blood donation; blood donors; blood establishments; blood group; blood loss; blood plasma; blood pressure; blood products; blood safety; blood samples; blood service; blood supply; blood system; blood transfusion; blood units; blood volume; cases; clinical; complications; concentrates; conclusion; control; cord blood; count; data; day; days; detection; disease; dna; donations; effect; events; factor; ffp; following; frequency; general; groups; hbsag; hbv; hcv; health; high; hla; hospital; hospital blood; identification; important; increase; infections; information; introduction; iron; laboratory; level; low; major; management; mean; medical; methods; national; negative; new; non; number; order; patients; pcr; period; plasma; platelet; platelet transfusion; population; positive; post; practice; presence; present; procedure; process; quality; range; rbc; rbc transfusion; rbcs; red; results; rhd; risk; routine; screening; serum; specific; standard; storage; studies; study; surgery; system; table; test; tested; testing; therapy; time blood; total; transfusion medicine; transfusion reactions; transfusion service; transfusion therapy; transfusions; treatment; type; use; weak; women; years cache: cord-023364-ut56gczm.txt plain text: cord-023364-ut56gczm.txt item: #165 of 449 id: cord-023442-4vzwc2d2 author: None title: Proceedings of SCANNING 94/SEEMS 94 Charleston, South Carolina, USA date: 2006-12-05 words: 55600 flesch: 45 summary: Applications include both thin-film and bulk x-ray microanalysis and examples of contrast in backscattered electron images obtained in the SEM. The effects of adjusting the Wehnelt-to-tip distance vary for different electron microscope systems. keywords: addition; analysis; associated; atomic; backscattered; carlo; cells; chemical; comparison; composition; conditions; confocal; contrast; cross; crystal; data; detection; detector; developed; development; distribution; drying; effects; electron; electron beam; electron microscopy; energy; field; fig; figure; form; formation; glass; image; imaging; laser; light; lines; material; measurement; method; microscope; milk; model; monte; new; number; particles; pattern; phase; point; preparation; probe; process; program; ray; region; resolution; results; sample; scanning; scattering; sections; sem; signal; silicon; simulation; size; specific; specimen; structures; studies; study; substrate; supplement; surface; system; techniques; temperature; time; tissue; transmission electron; type; use; vol; water; work cache: cord-023442-4vzwc2d2.txt plain text: cord-023442-4vzwc2d2.txt item: #166 of 449 id: cord-023713-daz2vokz author: Devereux, Graham title: Epidemiology of Asthma and Allergic Airway Diseases date: 2013-09-06 words: 27946 flesch: 44 summary: Asthma prevalence of less than 4% was found in Iceland, parts of Spain, Germany, Italy, Algeria, and India. The results for asthma prevalence are given in Figure 48 -9. keywords: adults; age; airway; allergy; association; asthma; asthma prevalence; atopic; birth; childhood asthma; children; cohort; disease; exposure; food; function; health; incidence; levels; life; lung; pollution; population; prevalence; risk; studies; study; symptoms; use; wheeze; wheezing; years cache: cord-023713-daz2vokz.txt plain text: cord-023713-daz2vokz.txt item: #167 of 449 id: cord-023913-pnjhi8cu author: Foreman, Stephen title: Broader Considerations of Medical and Dental Data Integration date: 2011-10-08 words: 47672 flesch: 38 summary: Over the past decade evidence has been building that there is a relationship between dental disease, particularly periodontal disease, and chronic illnesses. Dentists will need to be alert for early signs of chronic illness among their patients and physicians will need to be alert for signs of dental disease. keywords: access; association; benefi; care costs; caries; case; children; chronic; clinic; community; conditions; costs; coverage; data; dental; dentistry; dentists; diabetes; disease; education; ehr; et al; example; fig; genome; health; health care; health insurance; health record; healthcare; infl; information; insurance; management; medicaid; medical; medicare; medicine; national; need; new; number; oral; patient; patient care; periodontitis; population; practice; primary; program; providers; public; quality; record; report; research; risk; schools; students; studies; study; system; treatment; use; years cache: cord-023913-pnjhi8cu.txt plain text: cord-023913-pnjhi8cu.txt item: #168 of 449 id: cord-025304-qfpfllay author: Tiddi, Ilaria title: Fostering Scientific Meta-analyses with Knowledge Graphs: A Case-Study date: 2020-05-07 words: 5462 flesch: 32 summary: Conducting a meta-analysis then consists in: (1) Coding, i.e. annotating the studies with the relevant characteristics, including independent and dependent variables and effect sizes; (2) Analysis, i.e. estimating the overall effects using fixed and random effects models, determining heterogeneity in the studies, assessing publication bias, conducting moderator analyses through meta regression, performing statistical power analysis; (3) Interpretation, i.e. the presentation of the obtained results along with conclusions and graphical support, often including graphs such as forests, funnel, violin/scatter-box plots. Of course, resource allocation is highly dependent on the type meta-analysis performed (i.e. number of studies analysed, complexity of the question framed, number of moderator analyses...), and the same would lie when conducting metaanalyses with the support of our framework. keywords: analyses; cdo; cooperation; data; knowledge; meta; research; studies; study; variables cache: cord-025304-qfpfllay.txt plain text: cord-025304-qfpfllay.txt item: #169 of 449 id: cord-025366-haf542y0 author: Offit, Paul A. title: Vaccine safety date: 2012-11-07 words: 16638 flesch: 42 summary: 51 Because rare reactions, reactions with delayed onset, or reactions in subpopulations may not be detected before vaccines are licensed, postlicensure evaluation of vaccine safety is critical. In contrast with the methodological strengths of prelicensure randomized trials, however, postlicensure observational studies of vaccine safety pose a formidable set of methodological difficulties. keywords: care; cause; cells; children; data; disease; events; following; health; immunization; influenza; information; monitoring; number; parents; people; risk; safety; studies; study; vaccination; vaccine; vaccine safety; vaers cache: cord-025366-haf542y0.txt plain text: cord-025366-haf542y0.txt item: #170 of 449 id: cord-025495-udz9i0fw author: Nowak, Jan K. title: Lithium and coronaviral infections. A scoping review. date: 2020-04-03 words: 5351 flesch: 40 summary: GSk3-B is a widespread target for lithium effects and based its wide distribution in several organs and having several other subunits targeted as well as GSK-3B inhibitors failed in early studies with most of the related agents and did not mimic any clinical effects of lithium. Description of safety and limitations are generic in terms of lithium effects, except for the QT prolongation in combination with chloroquine, do not highlight the specific aspects related to the author's hypothesis, such as cell proliferation. keywords: concentrations; coronavirus; infections; lithium; patients; studies; virus cache: cord-025495-udz9i0fw.txt plain text: cord-025495-udz9i0fw.txt item: #171 of 449 id: cord-026392-cvb44v5v author: Dahlberg, Jørgen title: Barriers and challenges in the process of including critically ill patients in clinical studies date: 2020-06-08 words: 4783 flesch: 47 summary: Our study revealed that 38% of patient consents were oral, even though study investigators tried to obtain written consent whenever possible. Evaluating patient capacity in practice Informed consent during the clinical emergency of acute myocardial infarction (HERO-2 consent substudy): a prospective observational study Informed consent in clinical trials in critical care: experience from the PAC-man study An ethical analysis of proxy and waiver of consent in critical care research European legislation impedes critical care research and fails to protect patients' rights Confronting the ethical challenges to informed consent in emergency medicine research Inability to obtain deferred consent due to early death in emergency research: effect on validity of clinical trial results Research without informed patient consent in incompetent patients keywords: care; challenges; consent; kin; patients; research; study cache: cord-026392-cvb44v5v.txt plain text: cord-026392-cvb44v5v.txt item: #172 of 449 id: cord-026990-d3l1sbeb author: Oberoi, Sumit title: Economic menace of diabetes in India: a systematic review date: 2020-06-17 words: 4992 flesch: 54 summary: A large proportion of health care cost is confronted by the patients themselves, which affects the fulfilment of health care because of financial restraints [62] . The economic burden of diabetes in India: results from a national survey Cost of medical care among type 2 diabetic patients with a co-morbid conditionhypertension in India Direct costs associated with chronic kidney disease among type 2 diabetic patients in India Factors influencing medical tourism in India: a critical review Costs of diabetes The economic burden of depression in Sweden from Economic costs of diabetes in the US in 2002 A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections The prevalence of multi-morbidity in primary care and its effect on health care utilization and cost The burden of epilepsy for the patient: the intangible costs Economics of psychosocial factors in patients with cardiovascular disease The economic burden of diabetes in India: a review of the literature Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations keywords: burden; care; cost; diabetes; india; studies; study; total; zone cache: cord-026990-d3l1sbeb.txt plain text: cord-026990-d3l1sbeb.txt item: #173 of 449 id: cord-028963-u4iupl1s author: Lane, Michael title: Multiple Sclerosis date: 2020-07-10 words: 11874 flesch: 42 summary: About 15% of MS patients have progressive worsening from the onset of their illness, a form of MS referred to as primary progressive MS (PPMS). Given its safety profile and limited evidence on improving attention and executive function in MS, G. biloba standardized extract may benefit MS patients with cognitive impairment. keywords: acid; brain; diet; disease; fat; group; gut; levels; low; oil; patients; people; placebo; risk; sclerosis; stress; studies; study; subjects; supplementation; vitamin cache: cord-028963-u4iupl1s.txt plain text: cord-028963-u4iupl1s.txt item: #174 of 449 id: cord-029112-u507i0t0 author: Smith, Keisha title: A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial date: 2020-07-13 words: 20949 flesch: 39 summary: While the Investigator is not obligated to actively seek this information in former study patients, he or she may learn of an SAE through spontaneous reporting. key: cord-029112-u507i0t0 authors: Smith, Keisha; Pace, Amy; Ortiz, Stephan; Kazani, Shamsah; Rottinghaus, Scott title: A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial date: 2020-07-13 journal: Trials DOI: 10.1186/s13063-020-04548-z sha: doc_id: 29112 cord_uid: u507i0t0 OBJECTIVES: keywords: acute; alexion; alxn1210; amendment; bsc; complement; cov-305; covid-19; data; day; global; infection; information; infusion; intervention; investigator; lung; medical; patients; period; pregnancy; protocol; ravulizumab; sae; safety; study; time; treatment cache: cord-029112-u507i0t0.txt plain text: cord-029112-u507i0t0.txt item: #175 of 449 id: cord-029211-6o7qn2y2 author: None title: Press review date: 2020-07-15 words: 6214 flesch: 50 summary: Patients with digestive symptoms had a significantly longer time from onset to admission than patients without digestive symptoms (9.0 days vs 7.3 days). Patients age 18 years and older with T2T3 low rectal cancer, of maximum size 4 cm, who were clinically good responders after chemoradiotherapy (residual tumour ≤ 2 cm) were randomly assigned before surgery to either local excision or total mesorectal excision. keywords: group; icg; lymph; patients; rate; resection; study; surgery; survival cache: cord-029211-6o7qn2y2.txt plain text: cord-029211-6o7qn2y2.txt item: #176 of 449 id: cord-029423-o24dthlk author: Iwuji, Collins C. title: A phase IV randomised, open-label pilot study to evaluate switching from protease-inhibitor based regimen to Bictegravir/Emtricitabine/Tenofovir Alafenamide single tablet regimen in Integrase inhibitor-naïve, virologically suppressed HIV-1 infected adults harbouring drug resistance mutations (PIBIK study): study protocol for a randomised trial date: 2020-07-20 words: 6727 flesch: 38 summary: After informed consent, but prior to initiation of study treatment, all SAEs and adverse events related to protocol-mandated procedures would be reported on the CRFs. Following initiation of study treatment, all AEs, regardless of cause or relationship until 30 days post cessation of trial treatment would be reported on the CRFs. keywords: bpi; data; drug; hiv; participants; regimen; resistance; study; taf; tenofovir; treatment; trial; weeks cache: cord-029423-o24dthlk.txt plain text: cord-029423-o24dthlk.txt item: #177 of 449 id: cord-030371-wp6xmaqe author: Kubota, Kazuo title: Basic Science of PET Imaging for Inflammatory Diseases date: 2019-12-21 words: 15825 flesch: 33 summary: Preliminary results Quantification of temporal changes in calcium score in active atherosclerotic plaque in major vessels by (18)F-sodium fluoride PET/CT Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography Recent progress in the development of TSPO PET ligands for neuroinflammation imaging in neurological diseases Longitudinal imaging of microglia-astrocyte activation in mouse mesial temporal lobe epilepsy with TSPO PET to identify the best therapeutic time windows In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders Translocator protein-18 kDa (TSPO) positron emission tomography (PET) imaging and its clinical impact in neurodegenerative diseases Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies Distinct binding of amyloid imaging ligands to unique amyloid-beta deposited in the presubiculum of Alzheimer's disease In vivo visualization of tau accumulation, microglial activation, and brain atrophy in a mouse model of tauopathy rTg4510 Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography Comparative in vitro and in vivo quantifications of pathologic tau deposits and their association with neurodegeneration in tauopathy mouse models Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18) F-DPA-714 and micro-PET/CT 11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat TSPO imaging in parkinsonian disorders PET imaging of [(11)C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding Animal models of amyotrophic lateral sclerosis: a comparison of model validity Practical considerations for choosing a mouse model of Alzheimer's disease An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 Kinetic modeling without accounting for the vascular component impairs the quantification of [(11)C]PBR28 brain PET data Novel reference region model reveals increased microglial and reduced vascular binding of 11C-(R)-PK11195 in patients with Alzheimer's disease PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) Synthesis and initial in vivo evaluation of [(11) C]AZ683-a novel PET radiotracer for colony stimulating factor 1 receptor (CSF1R) Although the binding affinity in humans has been shown to vary due to polymorphism, TSPO PET has been employed as an effective tool to visualize and quantify the degree of neuroinflammation associated with glial activation in preclinical studies conducted using animal models, including rodents [106] . keywords: accumulation; activation; animal; binding; brain; cells; cns; disease; expression; fdg; fig; imaging; inflammation; macrophages; mice; microglia; model; mouse; neuroinflammation; pet; plaques; receptor; results; studies; study; tspo; uptake; vivo cache: cord-030371-wp6xmaqe.txt plain text: cord-030371-wp6xmaqe.txt item: #178 of 449 id: cord-030679-27qrlapp author: Yamamoto, Ryo title: Oxygen administration in patients recovering from cardiac arrest: a narrative review date: 2020-08-12 words: 4289 flesch: 31 summary: Group Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest Hyperoxia in the intensive care unit and outcome after out-of-hospital ventricular fibrillation cardiac arrest Association between mean arterial blood gas tension and outcome in cardiac arrest patients treated with therapeutic hypothermia Early hyperoxemia may not increase mortality after cardiac arrest: a pilot study The value of arterial blood gas parameters for prediction of mortality in survivors of out-ofhospital cardiac arrest Hyperoxia early after hospital admission in comatose patients with nontraumatic out-of-hospital cardiac arrest Arterial blood gas tensions after resuscitation from out-of-hospital cardiac arrest: associations with long-term neurologic outcome Association between intra-and post-arrest hyperoxia on mortality in adults with cardiac arrest: a systematic review and meta-analysis. Resuscitation Cluster randomised comparison of the effectiveness of 100% oxygen versus titrated oxygen in patients with a sustained return of spontaneous circulation following out of hospital cardiac arrest: a feasibility study PROXY: post ROSC OXYgenation study Airway and ventilation management during cardiopulmonary resuscitation and after successful resuscitation Ventilator management and respiratory care after cardiac arrest: oxygenation, ventilation, infection, and injury Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Authors' contributions RY and JY performed the review of literature and contributed in writing the manuscript. keywords: arrest; cardiac; hyperoxia; oxygen; pao; patients; study cache: cord-030679-27qrlapp.txt plain text: cord-030679-27qrlapp.txt item: #179 of 449 id: cord-030725-876arxiu author: None title: September 2020 New in Review date: 2020-08-20 words: 2745 flesch: 41 summary: Clinical significance of nutritional risk screening for older adult patients with COVID-19. Lifestyle factors documented included smoking status, alcohol intake, and diet by way of a food frequency questionnaire. keywords: age; analysis; participants; risk; sample; status; study; vitamin; weight; years cache: cord-030725-876arxiu.txt plain text: cord-030725-876arxiu.txt item: #180 of 449 id: cord-030922-l7xuu9a5 author: Bergström, Anna title: The use of the PARIHS framework in implementation research and practice—a citation analysis of the literature date: 2020-08-27 words: 12743 flesch: 26 summary: [5] as one of the two primary originating sources of influence in their citation analysis of dissemination and implementation frameworks. Empirical review articles (n = 11) included reviews of implementation frameworks [3, 313, 323, 324, [332] [333] keywords: action; analysis; articles; care; context; development; evaluation; evidence; facilitation; findings; framework; health; implementation; intervention; knowledge; nursing; parihs; parihs framework; practice; research; review; studies; study; use cache: cord-030922-l7xuu9a5.txt plain text: cord-030922-l7xuu9a5.txt item: #181 of 449 id: cord-031243-p6142nt1 author: Lewis, Mae M. title: From Study-Abroad to Study-at-Home: Teaching Cross-Cultural Design Thinking During COVID-19 date: 2020-09-01 words: 3107 flesch: 41 summary: While we endeavored to be readily available to online students via Slack, interactions were still limited by comparison. In the end-ofcourse self-reflections, several online students regretted missing the Sa˜o Joa˜o festival. keywords: abroad; course; format; learning; online; self; students; study cache: cord-031243-p6142nt1.txt plain text: cord-031243-p6142nt1.txt item: #182 of 449 id: cord-031907-ilhr3iu5 author: None title: ISEV2020 Abstract Book date: 2020-07-15 words: 201435 flesch: 40 summary: Normal pancreas cells (hTERT-HPNE and HPDE-H6c7) were co-cultured with cancer cell EVs for 24-48 hours. Before EV isolation cells were kept for 24 h either under normoxia or hypoxia (1% oxygen). keywords: ability; activation; activity; ad evs; addition; aim; analysis; analysis methods; anti; approach; assay; associated; bacterial evs; biological; biomarkers; blood; blood cells; blood evs; blot; bone; brain; breast; breast cancer; cancer cells; cancer evs; cancer introduction; cancer patients; cd63; cd81; cd9; cell communication; cell culture; cell evs; cell exosomes; cell function; cell lines; cell proliferation; cell surface; cell types; cells; cells introduction; changes; characterization; chromatography; composition; concentration; conclusion; conditions; content; control; control evs; cultured; current; cytometry; data; delivery; density; detection; development; diagnosis; differential; disease; distribution; dna; drug; effect; electron; endothelial; enrichment; epithelial; ev analysis; ev cargo; ev evs; ev isolation; ev markers; ev numbers; ev preparations; ev production; ev protein; ev release; ev research; ev rna; ev samples; ev subpopulations; ev surface; ev treatment; ev uptake; evs; exclusion; exosomal; exosomes; experiments; expression; expression analysis; extracellular; factors; findings; flow; fluorescent; fluorescent evs; fold; formation; fractions; free; function; funding; gene; group; growth; host cells; human; human evs; imaging; immune; increase; inflammation; inflammatory; introduction; isolated; isolation methods; key; large; levels; lipid; lung; macrophages; mass; mechanisms; media; medium; membrane; membrane vesicles; mesenchymal; metastasis; methods; mice; microscopy; migration; milk evs; mirna; model; molecular; molecules; mouse; msc evs; mscs; nanoparticle; national; neuronal; neurons; new; non; normal; novel; nta; number; particles; pathway; patients; plasma evs; plasma samples; platelet; platform; play; positive; positive evs; post; potential; presence; present; primary; process; production; profile; profiling; progression; proliferation; properties; prostate; prostate cancer; protein; protein cargo; protein expression; protein markers; proteomic; purification; purity; range; recipient cells; research; resistance; response; results; rna; rnas; role; samples; sec; secretion; sequencing; serum; sevs; signalling; single; size; small evs; specific; specific evs; spectrometry; stem cells; stromal cells; studies; study; summary; surface; system; target cells; targets; tau; techniques; tested; therapeutic; therapy; time; tissue; total; total evs; tracking; transfer; transmission; treatment; tumour cells; ultracentrifugation; university; uptake; urinary evs; urine; usa; usa introduction; use; vesicles; vesicles introduction; vitro; vivo; work cache: cord-031907-ilhr3iu5.txt plain text: cord-031907-ilhr3iu5.txt item: #183 of 449 id: cord-032379-pelz3ygf author: None title: October 2020 New in Review date: 2020-09-21 words: 3599 flesch: 42 summary: Eligibility criteria included journal articles describing at least one tool potentially used by health care providers to promote healthy dietary intake in healthy, pregnant women; and articles published in Western countries. The investigators sought a review of tools to be integrated into antenatal care for promotion of healthy dietary behavior in healthy pregnant women. keywords: analysis; data; dietary; health; intervention; participants; randomized; researchers; review; sample; studies; study; weight cache: cord-032379-pelz3ygf.txt plain text: cord-032379-pelz3ygf.txt item: #184 of 449 id: cord-032623-32m3qko4 author: Durkin, Louisa title: When mycologists describe new species, not all relevant information is provided (clearly enough) date: 2020-09-10 words: 7475 flesch: 47 summary: Our results show that the target audience of fungal species descriptions appears to be other fungal taxonomists, because many aspects of the new species were presented only implicitly, if at all. But is that really happening? To assess whether fungal species descriptions are attuned to both the wants and needs of a target audience beyond taxonomists and the sign of the times, we explored 10 years' worth of fungal species descriptions of extant mycological taxa in five major mycological journals (plus one botany journal for reference) for a range of factors pertaining to inter-and intra-scientific terms and concepts, science-demographical aspects, and illustrations and visualisations (Tables 1, 2; Suppl. keywords: -whether; authors; data; descriptions; fungal; mycological; number; papers; species; studies; taxonomic; taxonomy cache: cord-032623-32m3qko4.txt plain text: cord-032623-32m3qko4.txt item: #185 of 449 id: cord-032926-mrnsaexq author: Waitz, Markus title: Application of two different nasal CPAP levels for the treatment of respiratory distress syndrome in preterm infants—“The OPTTIMMAL-Trial”—Optimizing PEEP To The IMMAture Lungs: study protocol of a randomized controlled trial date: 2020-10-01 words: 6996 flesch: 41 summary: To The IMMAture Lungs: study protocol of a randomized controlled trial date: 2020-10-01 journal: Trials DOI: 10.1186/s13063-020-04660-0 sha: doc_id: 32926 cord_uid: mrnsaexq BACKGROUND: Local principal investigators and team members are required to participate in a pre-study meeting where details of study protocol, data collection, the application, and adjustments of PEEP will be discussed. keywords: cmh; cpap; data; infants; nasal; peep; pressure; preterm; protocol; study; treatment; ventilation cache: cord-032926-mrnsaexq.txt plain text: cord-032926-mrnsaexq.txt item: #186 of 449 id: cord-033736-bsmqqi6j author: Bajraktari, Saranda title: Health-promoting and preventive interventions for community-dwelling older people published from inception to 2019: a scoping review to guide decision making in a Swedish municipality context date: 2020-10-14 words: 10551 flesch: 37 summary: To summarise intervention effects, we classified health outcomes in broader categories (Table 3) . However, these findings on long-term effects are in contrast to a previous PHV trial that indicated that intervention effects remained only for as long as the home visits were ongoing [111] , and thus, highlights the importance of long term follow-ups over. keywords: community; cost; dwelling; effects; exercise; group; health; home; interventions; people; prevention; review; studies; study; trial cache: cord-033736-bsmqqi6j.txt plain text: cord-033736-bsmqqi6j.txt item: #187 of 449 id: cord-034339-1fgbubsc author: Holz, N. E. title: Kohortenstudien in der Kinder- und Jugendpsychiatrie date: 2020-10-28 words: 3151 flesch: 31 summary: Auch familiäre Widrigkeiten in der Kindheit wiesen Langzeiteffekte in Bezug auf einen frühen Beginn der SSV-Symptomatik und verminderte Aktivität in der Amygdala während der Emotionsverarbeitung als auch des ventralen Striatums während der Belohnungsverarbeitung auf Als weitere frühe Risikofaktoren für vor allem externalisierende Störungen in der Kindheit haben sich postpartale Depression keywords: als; auch; auf; bei; bis; cohort; der; des; die; disorders; eine; erwachsenenalter; für; kindheit; longitudinal; mit; risk; sich; studies; study; und; von; werden; während; years cache: cord-034339-1fgbubsc.txt plain text: cord-034339-1fgbubsc.txt item: #188 of 449 id: cord-102417-xn7m3wqp author: Blake, T. title: Psoriatic disease and body composition: a systematic review of the literature date: 2020-05-21 words: 4710 flesch: 43 summary: [18] The risk of bias quality assessment of included studies is presented in Table 3 . We suggest that body composition indices should be analyzed in more detail with a broader range of techniques and imaging systems across the clinical spectrum of psoriatic patients in order to generate validated methods of assessment, particularly with regards to the prognostic ability of BIA and PhA. Further studies are needed to address the discrepancies in bioimpedance parameters within body compartments and between different devices and the deviation from health to disease. keywords: body; composition; disease; fat; mass; patients; preprint; psoriasis; psoriatic; review; studies cache: cord-102417-xn7m3wqp.txt plain text: cord-102417-xn7m3wqp.txt item: #189 of 449 id: cord-102474-fmq98aa8 author: Gooding, K. M. title: Prognostic Imaging Biomarkers for Diabetic Kidney Disease (iBEAt): Study protocol date: 2020-01-16 words: 5711 flesch: 37 summary: An additional aim of the iBEAT study is to establish a biobank of biological samples (blood-and urine-based) from well-characterised patients for use within the BEAt-DKD programme and future DKD studies. The iBEAT study, part of the BEAt-DKD consortium, aims to determine whether renal imaging biomarkers (magnetic resonance imaging (MRI) and ultrasound (US)) provide insight into the pathogenesis and heterogeneity of DKD (primary aim), and whether they have potential as prognostic biomarkers in DKD progression (secondary aim). keywords: biomarkers; blood; clinical; data; diabetes; dkd; egfr; ibeat; imaging; kidney; mri; preprint; renal; study cache: cord-102474-fmq98aa8.txt plain text: cord-102474-fmq98aa8.txt item: #190 of 449 id: cord-102796-rr8qet8c author: Counotte, Michel J title: Emergence of evidence during disease outbreaks: lessons learnt from the Zika virus outbreak date: 2020-03-18 words: 3047 flesch: 53 summary: In the 2013-2016 ZIKV outbreak, case reports, case series and basic research studies were published first. For basic research studies, many of which were done in countries unaffected by 85 ZIKV, we assigned the time to publication as the time between 1 February 2016 (the PHEIC declaration) 86 and the first available publication date. keywords: evidence; license; preprint; publication; time cache: cord-102796-rr8qet8c.txt plain text: cord-102796-rr8qet8c.txt item: #191 of 449 id: cord-103522-94zqk6lu author: Shah, S. G. S. title: Are digital technology interventions effective to reduce loneliness in older adults? A systematic review and meta-analysis date: 2020-09-01 words: 6395 flesch: 34 summary: Thus, we also avoided the overestimation of the effect of intervention in the absence of a control group (57) in the pre and post intervention study (56). The characteristics of included studies (n=6) are given in Tables 2. keywords: abstract; adults; analysis; follow; intervention; loneliness; medrxiv; meta; preprint; review; studies cache: cord-103522-94zqk6lu.txt plain text: cord-103522-94zqk6lu.txt item: #192 of 449 id: cord-151118-25cbus1m author: Murray, Benjamin title: Accessible Data Curation and Analytics for International-Scale Citizen Science Datasets date: 2020-11-02 words: 4954 flesch: 54 summary: Categorical fields Categorical fields map a limited set of string values to a corresponding numeric value. ExeTera's merging API allows the user to think in a tabular fashion by accepting tuples of ExeTera fields, which only load their contents when specifically requested. keywords: covid; data; dataset; exetera; fields; format; scale; study; symptom; test cache: cord-151118-25cbus1m.txt plain text: cord-151118-25cbus1m.txt item: #193 of 449 id: cord-170195-lrg11s5n author: Stoye, Jorg title: A Critical Assessment of Some Recent Work on COVID-19 date: 2020-05-20 words: 2765 flesch: 58 summary: Although this distinction is central to how we teach hypothesis tests, including in medicine (Altman and Bland, 1995) , it is at most barely maintained in the paper (see the aforecited sentence) and completely lost in its perception. [6] different extrapolation that would align the study with other recent seroprevalence studies (and have shorter confidence intervals to boot) was not discussed. keywords: age; analysis; data; gangelt; study; test cache: cord-170195-lrg11s5n.txt plain text: cord-170195-lrg11s5n.txt item: #194 of 449 id: cord-216972-migs9rxb author: Garaialde, Diego title: Quantifying the Impact of Making and Breaking Interface Habits date: 2020-05-14 words: 6292 flesch: 44 summary: 6.1.2 Adapting interfaces to account for user habits. key: cord-216972-migs9rxb authors: Garaialde, Diego; Bowers, Christopher P.; Pinder, Charlie; Shah, Priyal; Parashar, Shashwat; Clark, Leigh; Cowan, Benjamin R. title: Quantifying the Impact of Making and Breaking Interface Habits date: 2020-05-14 journal: nan DOI: nan sha: doc_id: 216972 cord_uid: migs9rxb The frequency with which people interact with technology means that users may develop interface habits, i.e. fast, automatic responses to stable interface cues. keywords: accuracy; habit; interface; participants; performance; phase; response; study; task; time; user cache: cord-216972-migs9rxb.txt plain text: cord-216972-migs9rxb.txt item: #195 of 449 id: cord-251962-xeue441p author: Armour, Cherie title: The COVID-19 Psychological Wellbeing Study: Understanding the Longitudinal Psychosocial Impact of the COVID-19 Pandemic in the UK; a Methodological Overview Paper date: 2020-11-04 words: 10295 flesch: 46 summary: In recognising this, a team of leading mental health scientists published a position paper detailing a number of mental health research priorities for the UK in response to the COVID-19 pandemic. These included the need for increased monitoring and reporting of the rates of mental health issues and a need to determine the factors that adversely or positively affect mental health during this time. keywords: covid-19; data; et al; health; pandemic; participants; research; sample; scale; study; survey; time; wellbeing cache: cord-251962-xeue441p.txt plain text: cord-251962-xeue441p.txt item: #196 of 449 id: cord-252691-757mh2mh author: Pratt, R. J. title: epic2: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England date: 2007-02-28 words: 25529 flesch: 33 summary: A randomized, double-blind trial Decreasing catheter colonization through the use of an antiseptic-impregnated catheter: a continuous quality improvement project A comparison of two antimicrobialimpregnated central venous catheters Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection: a meta-analysis Prevention of intravascular catheter-related infections Prevention of bloodstream infections with central venous catheters treated with anti-infective agents depends on catheter type and insertion time: evidence from a meta-analysis Prolonged antimicrobial activity of a catheter containing chlorhexidine/silver sulfadiazine extends protection against catheter infections in vivo The clinical and cost effectiveness of central venous catheters treated with anti-microbial agents in preventing bloodstream infections: a systematic review and economic evaluation The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: a prospective study utilizing molecular subtyping Prospective multicenter study of vascular-catheter-related complications and risk factors for positive centralcatheter cultures in intensive care unit patients Risk of infection due to central venous catheters: effect of site of placement and catheter type Femoral deep vein thrombosis associated with central venous catheterization: results from a prospective, randomized trial Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial Deep venous thrombosis caused by femoral venous catheters in critically ill adult patients Incidence of deep venous thrombosis associated with femoral venous catheterization A prospective evaluation of the use of femoral venous catheters in critically ill adults Ultrasound guidance for placement of central venous catheters: a meta-analysis of the literature Guidance on the use of ultrasound locating devices for placing central venous catheters Peripheral access options Skin microbiology: coming of age Risk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patients aseptic technique is very important: maximal barrier precautions during insertion reduce the risk of central venous catheter-related bacteremia Improved sterile technique diminishes the incidence of positive line cultures in cardiovascular patients Prevention of central venous catheter-related infections by using maximal sterile barrier precautions during insertion Infections due to Infusion Therapy Catheter-Related Bloodstream Infections: Evaluation of CDC Guidelines Catheter-related sepsis: an overview -Part 2 Using maximal sterile barriers to prevent central venous catheter-related infection: A systematic evidence-based review Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients Prospective randomized trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients Guideline for use of topical antimicrobial agents Catheter-related sepsis in long-term parenteral nutrition with Broviac catheters. [181] [182] A systematic review supports these findings in that it suggests that adding bacterial solutions to drainage bags has no effect on catheter associated infection. keywords: alcohol; analysis; bsi; care; catheter; contamination; control; cvad; evidence; gloves; guidelines; hand; healthcare; hospital; hygiene; infection; insertion; meta; national; patients; practice; prevention; recommendations; review; risk; site; studies; study; systematic; use; venous cache: cord-252691-757mh2mh.txt plain text: cord-252691-757mh2mh.txt item: #197 of 449 id: cord-252922-cdhnlvxv author: West, Erin A. title: Corona Immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland date: 2020-10-24 words: 5480 flesch: 37 summary: Seroprevalence studies to assess the spread of SARS-CoV-2 infection in the general population and subgroups are key for evaluating mitigation and vaccination policies and for understanding the spread of the disease both on the national level and for comparison with the international community. We define our general, population-based studies as seroprevalence studies and our subpopulation studies as seroepidemiological studies per the lexicon defined by Horby et al. (2017) . keywords: corona; cov-2; health; immunitas; infection; pandemic; participants; population; sars; seroprevalence; studies; study; switzerland; test cache: cord-252922-cdhnlvxv.txt plain text: cord-252922-cdhnlvxv.txt item: #198 of 449 id: cord-252984-79jzkdu2 author: Bickman, Leonard title: Improving Mental Health Services: A 50-Year Journey from Randomized Experiments to Artificial Intelligence and Precision Mental Health date: 2020-07-26 words: 35544 flesch: 44 summary: Confidentiality and trust are key issues in mental health treatment. I was trained as a social psychologist and was a graduate student of Stanley Milgram (of the famous obedience experiments), so I was curious about the research on the relationship between technological virtual agents and humans beyond the context of mental health treatment. keywords: analysis; approach; authors; bickman; care; causal; children; clinical; clinicians; data; depression; effectiveness; et al; evidence; feedback; health; health services; human; interventions; issue; learning; machine; medicine; mental; meta; need; new; outcomes; paper; potential; precision; problems; psychiatry; rcts; research; review; services research; social; studies; study; system; therapy; time; treatment; use cache: cord-252984-79jzkdu2.txt plain text: cord-252984-79jzkdu2.txt item: #199 of 449 id: cord-253000-nwbmxepi author: Margină, Denisa title: Chronic Inflammation in the Context of Everyday Life: Dietary Changes as Mitigating Factors date: 2020-06-10 words: 8289 flesch: 25 summary: Studies on animal models show an improvement in neurodegenerative diseases after fasting, while other studies prove that intermittent fasting diets boost the levels of antioxidant defense, neurotrophic factors (BDNFS, H-70 and FGF2), proteins involved in adaptive response (HSP-70 and GRP-78), and reduce pro-inflammatory cytokines levels (TNFa, IL-1β, and IL-6) SCFAs have anti-inflammatory effects that bind to the nuclear transcription factor PPARγ (peroxisome proliferator-activated receptor γ) and, consequently, inhibit the NF-kB pathway keywords: body; cells; changes; day; diet; diseases; effects; fasting; gut; health; inflammation; insulin; intermittent; metabolic; obese; risk; studies; study; weight cache: cord-253000-nwbmxepi.txt plain text: cord-253000-nwbmxepi.txt item: #200 of 449 id: cord-253525-r6ocr18h author: Fontbonne, Alain title: Small animal reproduction: Scientific facts versus dogmas or unverified beliefs date: 2020-03-11 words: 7003 flesch: 42 summary: Theriogenology Diseases of the canine uterus Cystic endometrial hyperplasia, pseudoplacentational endometrial hyperplasia, and other cystic conditions of the canine and feline uterus BSAVA Manual of canine and feline reproduction Treatment of fibroadenomatosis in 14 cats with aglepristonechanges in blood parameters and follow-up Comment traiter la fibroad enomatose et la mastose chez la chatte Clinical approach to conditions of the non-pregnant and neutered bitch Vaginal diseases Cystic ovaries and ovarian neoplasia in the female dog -a systematic review Descriptive analysis of the abstracts printed in the successive proceeding books of the EVSSAR congresses from 1998 to 2015, which have not been published in international peer-reviewed journals Bacterial reproductive pathogens of cats and dogs Mycoplasmas in dogs: significance, diagnosis and treatment Viral reproductive pathogens of dogs and cats Disease transmission by mating or artificial insemination in the cat: concerns and prophylaxis Prevalence of feline Chlamydia psittaci and feline herpesvirus 1 in cats with upper respiratory tract disease Isolation of Brucella abortus from a dog and a cat confirms their biological role in Re-emergence and dissemination of bovine brucellosis on dairy farms Experimental infection of pregnant queens with two major Brazilian clonal lineages of Toxoplasma gondii Influence des ant ec edents hormonaux sur l'apparition clinique des tumeurs mammaires chez la chienne classification and prognosis of mammary tumours in the canine and feline species Pseudopregnancy and mammary tumors development ion the bitch Clinical efficacy of a GnRH-agonist implant containing 4.7 mg deslorelin, Suprelorin, regarding suppression of reproductive function in tomcats Contraceptive implants used by cat breeders in France, a study on 140 purebred cats Uterine drainage in the bitch for treatment of pyometra refractory to prostaglandin F2a Surgical uterine drainage and lavage as treatment for caninepyometra The relationship of urinary incontinence to early spaying in bitches Acquired urinary incontinence in bitches: its incidence and relationship to neutering practices Associations between neutering and early-onset urinary incontinence in UK bitches under primary veterinary care Effect of spaying and timing of spaying on survival of dogs with mammary carcinoma Effect of ovariohysterectomy in bitches with mammary neoplasms Stimulation of mating-induced uterine contractions in the bitch and their modification and enhancement of fertility by prostatic fluid Intravaginal insemination of bitches with fresh and frozenthawed semen with addition of prostatic fluid: use of an infusion pipette and the Osiris catheter Comparison of fertility data from vaginal vs intrauterine insemination of frozen-thawed dog semen: a retrospective study Pregnancy and conception rate after two intravaginal inseminations with dog semen frozen either with 5% glycerol or 5% ethylene glycol GnRH analogue treatment on LH surge day 0 followed by single transvaginal artificial insemination with frozen semen on day 5 in bitches The effect of pre-ovulatory anaesthesia on ovulation in laparoscopically inseminated domestic cats Artificial intravaginal insemination using fresh semen in cats The effect of Equex STM paste and sperm morphology on post-thaw survival of cat epididymal spermatozoa Quality and fertilizing ability of electroejaculated cat spermatozoa frozen with or without Equex STM Paste Gonadectomy in cats and dogs: a review of risks and benefits Neutering dogs: effects on joint disorders and cancers in golden retrievers Cutaneous MCTs: associations with spay/neuter status, breed, body size, and phylogenetic cluster The role of neutering in cancer development Results of vulvoplasty for treatment of recessed vulva in dogs Clinical use of deslorelin implants for the long-term contraception in prepubertal bitches: effects on epiphyseal closure, body development, and time to puberty The author wishes to thank Mrs. Felicity Leith-Ross for her great help in improving the English language, and all his colleagues of the CERCA (Centre d'Etude en Reproduction des Carnivores), especially Dr Natalia Santos and Dr.Cindy Maenhoudt. Another frequent statement is that bitches -to the contrary of queens -are non-seasonal breeders, because they may exhibit oestrus at any time of the year and litters are born during each month of the year keywords: bitches; cats; diseases; dogs; neutering; pregnancy; reproduction; risk; sar; studies; study cache: cord-253525-r6ocr18h.txt plain text: cord-253525-r6ocr18h.txt item: #201 of 449 id: cord-255230-i6q73bhs author: Makhanova, Anastasia title: Capturing Fluctuations in Pathogen Avoidance: the Situational Pathogen Avoidance Scale date: 2020-08-13 words: 12476 flesch: 47 summary: Future research can benefit from using the SPA scale alongside existing pathogen avoidance scales to further examine parallel and divergent effects associated with chronic versus situational sources of pathogen avoidance. Although the present research validated the scale's function by assessing how experimental manipulations of pathogen threat increase SPA scores, pathogen avoidance is also affected by other situations such as being rejected (Sacco et al. 2014) or imagining oneself in a crowded place (Brown and Sacco 2020) . keywords: avoidance; et al; participants; pathogen; pathogen avoidance; scale; scores; spa; spa scale; spa scores; study; threat cache: cord-255230-i6q73bhs.txt plain text: cord-255230-i6q73bhs.txt item: #202 of 449 id: cord-255351-vp19ydce author: Lanata, Claudio F. title: Global Causes of Diarrheal Disease Mortality in Children <5 Years of Age: A Systematic Review date: 2013-09-04 words: 5453 flesch: 43 summary: We stratified studies by the number of pathogens sought and calculated the unadjusted and age-adjusted medians, as described above, separately for single pathogen studies and for studies that sought 5 to 13 pathogens. GBD used rates reported in diarrhea studies published between 1975 and 2010 done in outpatients, casecontrol, and community-based studies as a reference category to adjust the proportions seen in inpatient studies. keywords: age; children; deaths; diarrhea; estimates; pathogens; rotavirus; studies; study; years cache: cord-255351-vp19ydce.txt plain text: cord-255351-vp19ydce.txt item: #203 of 449 id: cord-255877-k8r98w3e author: Toye, Francine title: A qualitative evidence synthesis using meta-ethnography to understand the experience of living with pelvic organ prolapse date: 2020-09-01 words: 4515 flesch: 51 summary: National Institute of Clinical Excellence guideline NG123 NG123 Urogynaecological prolapse and stress urinary incontinence using tape or mesh: hospital episode statistics (HES), experimental statistics Update on the Independent Medicines and Medical Devices Safety Review: Written statement -HCWS841 Living life precariously with rheumatoid arthritis -a mega-ethnography of nine qualitative evidence syntheses A systematic review and meta-synthesis of qualitative studies on pelvic organ prolapse for the development of core outcome sets Meta-ethnography: Synthesising Qualitative Studies A meta-ethnography to understand the experience of living with urinary incontinence: 'is it just part and parcel of life Improving reporting of meta-ethnography: the eMERGe reporting guidance Brimful of STARLITE: toward standards for reporting literature searches Appraising qualitative research for inclusion in systematic reviews: a quantitative and qualitative comparison of three methods Applying GRADE-CERQual to qualitative evidence synthesis findings: introduction to the series Women's experiences of receiving care for pelvic organ prolapse: a qualitative study Women's expectations of prolapse surgery: a retrospective qualitative study Barriers to seeking treatment for women with persistent or recurrent symptoms in urogynaecology A qualitative study of women's preferences for treatment of pelvic floor disorders Strengthening validity in studies of pelvic floor disorders through qualitative research: an example from Ethiopia Factors enabling women with pelvic organ prolapse to seek surgery at mobile surgical camps in two remote districts in Nepal: a qualitative study Pelvic organ prolapse: a disease of silence and shame The emotional burden of pelvic organ prolapse in women seeking treatment: a qualitative study Life after pelvic organ prolapse surgery: a qualitative study in Amhara region The lucky ones get cured: health care seeking among women with pelvic organ prolapse in Amhara region Living with pelvic organ prolapse: voices of women from Amhara region Women's experiences of doing long-term pelvic floor muscle exercises for the treatment of pelvic organ prolapse symptoms Knowledge, perceptions, and attitudes toward pelvic organ prolapse and urinary incontinence in Spanish-speaking Latinas Patients' understanding of pelvic floor disorders: what women want to know Falling out: authoritative knowledge and women's experiences with pelvic organ prolapse Body image perceptions in women with pelvic organ prolapse: a qualitative study Not the surgery for a young person: women's experience with vaginal closure surgery for severe prolapse A hidden disorder until the pieces fall into place'-a qualitative study of vaginal prolapse Pelvic floor dysfunction: women's sexual concerns unraveled The impact of pelvic floor surgery on female sexual function: a mixed quantitative and qualitative study The pessary process: Spanish-speaking Latinas' experience Communication between physicians and Spanish-speaking Latin American women with pelvic floor disorders: a cycle of misunderstanding? Women's experiences and health care-seeking practices in relation to uterine prolapse in a hill district of Nepal Fallen uterus: social suffering, bodily vigor, and social support among women in rural Mexico Women's experiences with vaginal pessary use Conceptual framework for patient-important treatment outcomes for pelvic organ prolapse Misconceptions and miscommunication among Spanish-speaking and English-speaking women with pelvic organ prolapse Body image and sexuality in women with pelvic organ prolapse Health care disparities among English-speaking and Spanish-speaking women with pelvic organ prolapse at public and private hospitals: what are the barriers? We included qualitative studies that explored the experience of POP. keywords: experience; organ; pelvic; pop; prolapse; studies; women cache: cord-255877-k8r98w3e.txt plain text: cord-255877-k8r98w3e.txt item: #204 of 449 id: cord-255901-nl9k8uwd author: Barasheed, Osamah title: Uptake and effectiveness of facemask against respiratory infections at mass gatherings: a systematic review date: 2016-03-29 words: 4523 flesch: 42 summary: key: cord-255901-nl9k8uwd authors: Barasheed, Osamah; Alfelali, Mohammad; Mushta, Sami; Bokhary, Hamid; Alshehri, Jassir; Attar, Ammar A.; Booy, Robert; Rashid, Harunor title: Uptake and effectiveness of facemask against respiratory infections at mass gatherings: a systematic review date: 2016-03-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2016.03.023 sha: doc_id: 255901 cord_uid: nl9k8uwd OBJECTIVES: The risk of acquisition and transmission of respiratory infections is high among attendees of mass gatherings (MGs). keywords: effectiveness; facemask; hajj; infections; influenza; pilgrims; respiratory; studies; study; uptake cache: cord-255901-nl9k8uwd.txt plain text: cord-255901-nl9k8uwd.txt item: #205 of 449 id: cord-256145-4rcy64y8 author: Menzies-Gow, Andrew title: DESTINATION: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the long-term safety and tolerability of tezepelumab in adults and adolescents with severe, uncontrolled asthma date: 2020-10-21 words: 5284 flesch: 36 summary: Patients aiming to enrol in the DESTINATION study who are not able to attend an onsite end of treatment visit in either predecessor study will continue to participate in the 12-week safety follow-up period of either NAVIGATOR (up to week 64) or SOURCE (up to week 60) until on-site randomization and administration of the first dose of study treatment in the DESTINATION study can be conducted. Patients aiming to enrol in the DESTINA-TION study who are not able to attend an onsite end of treatment visit in either predecessor study will continue to participate in the 12-week safety follow-up period of either NAVIGATOR (up to week 64) or SOURCE (up to week 60) until on-site randomization and administration of the first dose of study treatment in the DESTINATION study can be conducted. keywords: asthma; destination; patients; placebo; predecessor; safety; study; term; tezepelumab; treatment cache: cord-256145-4rcy64y8.txt plain text: cord-256145-4rcy64y8.txt item: #206 of 449 id: cord-256881-7sejcqda author: Heindel, Jerrold J. title: Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies date: 2020-07-16 words: 24801 flesch: 42 summary: To address this critical gap, the present report represents a synthesis and integration of the results of 8 of the 14 independent studies by principal investigators willing to participate in an effort to coalesce the findings and assess patterns of BPA exposures across the various end organs examined in the same animal cohorts and, frequently, in the same animals. Collectively, the results provide unbiased evidence that BPA exposures at human-relevant doses result in adverse effects on the rat prostate gland. keywords: animals; bisphenol; bpa; bpa exposure; bpa studies; bpa study; clarity; data; day bpa; dose; dose bpa; effects; exposure; expression; female; gland; heart; hormone; low; males; mammary; mice; pnd; prostate; rats; results; studies; study; μg bpa cache: cord-256881-7sejcqda.txt plain text: cord-256881-7sejcqda.txt item: #207 of 449 id: cord-257073-dm80bxnd author: Akmatov, Manas K. title: E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology date: 2011-08-17 words: 3518 flesch: 42 summary: The non-responder survey allowed us to compare prospectively (participants) and retrospectively (non-responders) collected data on acute respiratory infection symptoms, and it revealed that the prospective approach resulted in a higher rate of detection of mild infections. key: cord-257073-dm80bxnd authors: Akmatov, Manas K.; Krebs, Stephan; Preusse, Matthias; Gatzemeier, Anja; Frischmann, Ursula; Schughart, Klaus; Pessler, Frank title: E-mail-based symptomatic surveillance combined with self-collection of nasal swabs: a new tool for acute respiratory infection epidemiology date: 2011-08-17 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2011.07.005 sha: doc_id: 257073 cord_uid: dm80bxnd OBJECTIVE: We examined the feasibility of combining communication by e-mail and self-collection of nasal swabs for the prospective detection of acute respiratory infections in a non-medical setting. keywords: influenza; nasal; participants; self; study; swab; time cache: cord-257073-dm80bxnd.txt plain text: cord-257073-dm80bxnd.txt item: #208 of 449 id: cord-257167-rz4r5sj7 author: None title: Abstracts for the 29th Annual Meeting of the Japan Neuroscience Society (Neuroscience2006) date: 2006-12-31 words: 241480 flesch: 43 summary: Inst., Kyoto Univ., Inuyama, Japan GABAergic cells in the cerebral cortex are divided into subgroups: parvalbumin (PV)-, somatostatin (SOM)-, calretinin (CR)-, and calbindin-containing types. In the present study, we therefore investigated the synthesis of sex steroids and corticosteroids in the hippocampus of adult male rats, by monitoring the metabolism of tritiated steroids with HPLC system. PS2A-G125 GABA depolarizes GnRH neurons isolated from adult GnRH-EGFP transgenic rats Chengzhu Yin, Nobuyuki Tanaka, Masakatsu Kato, Yasuo Sakuma Nippon Medical School, Department of physiology, Tokyo, Japan GnRH neurons are essential in the reproductive neuroendocrine system. keywords: 1,2; 100; acid; action; activation; activities; activity; addition; administration; adult; age; amplitude; amygdala; analysis; animals; antagonist; application; area; astrocytes; auditory; axons; bdnf; behavioral; binding; biology; body; brain; brain activity; brain development; brain function; brain research; brain science; bsi; ca1; calcium; camkii; cells; cellular; center; central; cerebellar; cerebral; changes; channel; chiba; cns; cognitive; complex; condition; contrast; control; correlation; cortex; cortex neurons; cortical; crest; cultured; current; data; days; death; decrease; dendrites; dendritic; department; dept; development; difference; differentiation; direction; disease; disorders; distribution; div; division; domain; dopamine; dopaminergic; dorsal; dynamics; effect; estrogen; evoked; excitatory; experiments; exposure; expression; eye; factors; family; fibers; field; findings; firing; fmri; following; formation; fos; frequency; function; funds; gaba; gabaergic; gene; gene expression; gfp; glutamate; gnrh neurons; graduate; granule; group; growth; gyrus; hand; health; high; hippocampal neurons; hippocampus; hiroshi; human; imaging; increase; individual; induced; induction; inhibition; inhibitory; injection; injury; inputs; institute; interaction; interneurons; intracellular; involvement; japan; japan brain; japan neural; japan neurons; japan science; jst; kakenhi; kinase; kyoto; kyoto university; lab; laboratory; layer; learning; left; level; life; like; localization; loss; ltd; ltp; male; manner; mechanisms; med; medical; medicine; membrane; memory; method; mice; microglia; migration; model; molecular; molecules; monkeys; motion; motor; motor neurons; mouse; mouse brain; movement; mrna; multiple; muscle; mutant; nagoya; national; nerve; nervous; network; neural; neurite; neuronal; neurons; neuroscience; new; nmda; non; novel; nuclei; nucleus; number; olfactory; onset; order; osaka; osaka university; pain; pathway; patients; pattern; period; phase; phosphorylation; physiology; plasticity; play; postnatal; postsynaptic; potential; prefrontal; presence; present; presynaptic; primary; process; processes; processing; progenitor cells; projection neurons; proliferation; properties; protein; ps2p; ps3a; ps3p; purkinje cells; pyramidal; rat brain; rate; rats; receptor; recorded; recording; reduced; region; regulation; relationship; release; report; required; research; research funds; research institute; response; results; reward; right; riken; role; saitama; school; sciences; second; selective; sensory; signaling; signals; site; size; slices; social; specific; spike; spinal; spines; state; stem cells; stimulation; stimuli; stimulus; stress; structure; studies; study; subjects; surface; synapses; synaptic; system; target; task; technology; temporal; term; terminals; test; time; tohoku; tokyo; tokyo university; transcription; transgenic; transmission; treatment; tsukuba; type; university; university graduate; university school; usa; visual; vitro; vivo; voltage; weeks; wild; zone cache: cord-257167-rz4r5sj7.txt plain text: cord-257167-rz4r5sj7.txt item: #209 of 449 id: cord-257244-gryp0khc author: Edwards, M. R. title: The potential of anti‐infectives and immunomodulators as therapies for asthma and asthma exacerbations date: 2017-08-10 words: 5758 flesch: 25 summary: Despite these important associations, the use of antiinfectives (antibiotics, antivirals, antifungals, vaccines) that specifically target known pathogens, or drugs that are based on or exploit microbe-host receptor interactions (toll-like receptor agonists, bacterial lysates) or are immunomodulators (vitamin D), and/or may work in part by altering our associated microbiology (probiotics) are, with the exception of severe asthma, seldom considered in asthma treatment, prevention and guidelines. Evidence to date suggested that modulation of the gut microbiome may represent an interesting therapeutic or preventative opportunity for the prevention of allergic asthma and AE, whilst clinical trials do not confirm initial enthusiastic expectations. keywords: antibiotics; asthma; childhood; children; disease; influenza; risk; studies; study; treatment; trial; use; virus cache: cord-257244-gryp0khc.txt plain text: cord-257244-gryp0khc.txt item: #210 of 449 id: cord-257400-mw38kfjo author: Iliadi, Anna title: Particulate Production and Composite Dust during Routine Dental Procedures. A Systematic Review with Meta-Analyses date: 2020-05-31 words: 5236 flesch: 40 summary: Five of the included studies were designed to assess composite dust generated in conditions of enamel clean-up after orthodontic fixed appliances removal [22, [27] PLoS ONE 2015 Outcome reporting discrepancies between trial entries and published final reports of orthodontic randomized controlled trials Bias in meta-analysis detected by a simple, graphical test Detection of nanoparticles released at finishing of dental composite materials Inhalation of aerosols produced during the removal of fixed orthodontic appliances: A comparison of 4 enamel cleanup methods Cytotoxic effects of composite dust on human bronchial epithelial cells Release of monomers from composite dust The effect of water spray on the release of composite nano-dust Cytotoxic and genotoxic potential of respirable fraction of composite dust on human bronchial cells Characterization and in vitro estrogenicity of orthodontic adhesive particulates produced by simulated debonding Airborne particles produced during enamel cleanup after removal of orthodontic appliances Quantitative and qualitative analysis of particulate production during simulated clinical orthodontic debonds Airborne exposure to gaseous and particle-associated organic substances in resin-based dental materials during restorative procedures Nanoparticle release from dental composites Particulate production during debonding of fixed appliances: Laboratory investigation and randomized clinical trial to assess the effect of using flash-free ceramic brackets A scoping review on bio-aerosols in healthcare and the dental environment Interventions to reduce aerosolized pathogens in dental practice. keywords: bias; composite; dust; grinding; handpiece; nano; particles; procedures; speed; studies; study; value cache: cord-257400-mw38kfjo.txt plain text: cord-257400-mw38kfjo.txt item: #211 of 449 id: cord-258087-93yfs7ve author: Flores, Carlos title: A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury date: 2008-10-25 words: 4740 flesch: 28 summary: Positive genetic association studies with acute lung injury/acute respiratory distress syndrome susceptibility and/or outcome (by year of publication) Percentage of studies scored as adequate for 14 criteria (x-axis) used for the quality assessment of genetic association studies supporting susceptibility and/or outcome in acute lung injury Percentage of studies scored as adequate for 14 criteria (x-axis) used for the quality assessment of genetic association studies supporting susceptibility and/or outcome in acute lung injury. key: cord-258087-93yfs7ve authors: Flores, Carlos; del Mar Pino-Yanes, Maria; Villar, Jesús title: A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury date: 2008-10-25 journal: Crit Care DOI: 10.1186/cc7098 sha: doc_id: 258087 cord_uid: 93yfs7ve INTRODUCTION: keywords: acute; ali; ards; association; genetic; injury; lung; outcome; studies; susceptibility cache: cord-258087-93yfs7ve.txt plain text: cord-258087-93yfs7ve.txt item: #212 of 449 id: cord-258399-difauneh author: Rahmani, Amir Masoud title: Coronavirus disease (COVID-19) prevention and treatment methods and effective parameters: A systematic literature review date: 2020-10-22 words: 10491 flesch: 39 summary: An Updated Meta-Analysis Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared pragmatic protocol A Case Report of a COVID-19-Associated Hyperactive Intensive Care Unit Delirium With Proposed Pathophysiology and Treatment Four point-of-care lateral flow immunoassays for diagnosis of COVID-19 and for assessing dynamics of antibody responses to SARS-CoV-2 SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients Understanding antibody testing for covid-19 Analyzing barriers for implementation of public health and social measures to prevent the transmission of COVID-19 disease using DEMATEL method The COVID-19 pandemic calls for spatial distancing and social closeness: not for social distancing Does culture matter social distancing under the COVID-19 pandemic Influence of wind and relative humidity on the social distancing effectiveness to prevent COVID-19 airborne transmission: A numerical study Population flow drives spatiotemporal distribution of COVID-19 in China Adolescents' motivations to engage in social distancing during the COVID-19 pandemic: Associations with mental and social health Predicting the Growth and Trend of COVID-19 Pandemic using Machine Learning and Cloud Computing Collective action and social distancing in COVID-19 responses. The positive impact of the review in various angles on people's level of awareness for self-caring and facing the disease An overall review has to investigate many proposed approaches to confront COVID-19 disease and the virus outbreak, whereas the previous SLR-based case studies focused on the particular fields of facing methods such as different observations of PCR's tests. keywords: case; covid-19; detection; disease; et al; health; impact; methods; outbreak; parameters; patients; people; studies; study; symptoms; treatment; virus; ✗ ✗ cache: cord-258399-difauneh.txt plain text: cord-258399-difauneh.txt item: #213 of 449 id: cord-258781-peppszqx author: Ishola, David A. title: Could influenza transmission be reduced by restricting mass gatherings? Towards an evidence-based policy framework date: 2011-08-18 words: 8477 flesch: 44 summary: The type of mass gathering event seems to be of considerable importance in terms of the risk of influenza transmission ( Table 7) . In summary, the type of mass gathering event seems to influence the risk of influenza transmission, key factors being the degree of crowdedness, the event duration and, possibly, whether the event is held indoors or outdoors. keywords: event; evidence; gatherings; hajj; health; influenza; mass; outbreak; pandemic; public; review; studies; study; transmission cache: cord-258781-peppszqx.txt plain text: cord-258781-peppszqx.txt item: #214 of 449 id: cord-259012-rk0sd9i5 author: Mehta, Hemal title: Trends in Real-World Neovascular AMD Treatment Outcomes in the UK date: 2020-10-14 words: 7106 flesch: 42 summary: Eye (Lond) Visual outcomes of age-related macular degeneration patients undergoing intravitreal ranibizumab monotherapy in an urban population Long-term visual outcomes of intravitreal ranibizumab treatment for wet age-related macular degeneration and effect on blindness rates in south-east Scotland Long-term outcomes of intravitreal ranibizumab for neovascular age-related macular degeneration in a well defined region of the UK Bilateral visual outcomes and service utilization of patients treated for 3 years with ranibizumab for neovascular age-related macular degeneration Long-term outcomes of aflibercept treatment for neovascular age-related macular degeneration in a clinical setting One-and two-year visual outcomes from the moorfields age-related macular degeneration database: a retrospective cohort study and an open science resource Predicting visual outcomes in patients treated with aflibercept for neovascular age-related macular degeneration: data from a real-world clinical setting Comparison of two intravitreal ranibizumab treatment schedules for neovascular age-related macular degeneration Effectiveness of ranibizumab for neovascular age-related macular degeneration using clinician-determined retreatment strategy UK AMD/DR EMR REPORT IX: comparative effectiveness of predominantly as needed (PRN) ranibizumab versus continuous aflibercept in UK clinical practice Three-year visual outcome and injection frequency of intravitreal ranibizumab therapy for neovascular age-related macular degeneration Real-world visual outcomes in patients with neovascular age-related macular degeneration receiving aflibercept at fixed intervals as per UK licence Three-year follow-up of ranibizumab treatment of wet age-related macular degeneration: influence of baseline visual acuity and injection frequency on visual outcomes Visual acuity outcomes in ranibizumab-treated neovascular age-related macular degeneration; stratified by baseline vision First-year visual acuity outcomes of providing aflibercept according to the VIEW Study Protocol for age-related macular degeneration Bevacizumab for neovascular age related macular degeneration (ABC trial): multicentre randomised double masked study 24-month clinical outcomes of a treat-and-extend regimen with ranibizumab for wet age-related macular degeneration in a real life setting Factors affecting visual acuity after one year of follow up after repeated intravitreal ranibizumab for macular degeneration Resource use and real-world outcomes for ranibizumab treat and extend for neovascular age-related macular degeneration in the UK: interim results from TERRA Impact of injection frequency on 5-year real-world visual acuity outcomes of aflibercept therapy for neovascular age-related macular degeneration Realworld visual and clinical outcomes for patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab: an 8-year observational cohort (AMD8) Second-year visual acuity outcomes of nAMD patients treated with aflibercept: data analysis from the UK Aflibercept Users Group. A meta-analysis was not carried out here, but if that is considered in a future analysis, the real-world studies would need to be weighted by number of study eyes and baseline characteristics adjusted for. keywords: age; baseline; clinical; degeneration; eyes; neovascular; outcomes; ranibizumab; studies; treatment; world; year cache: cord-259012-rk0sd9i5.txt plain text: cord-259012-rk0sd9i5.txt item: #215 of 449 id: cord-260112-tb087txz author: Kassardjian, Charles D. title: Practical Guidance for Managing EMG Requests and Testing during the COVID‐19 Pandemic date: 2020-04-11 words: 2028 flesch: 42 summary: Urgent EDX testing requests are those in which there is concern for an acute or rapidly evolving (over days to a week or two at most) peripheral neurological syndrome, where EDX testing would be confirmatively diagnostic and lead to specific and definitive management, and where not performing EDX studies would likely be detrimental because of delayed diagnosis and therefore, delayed treatment. We have stratified EDX studies into 3 categories: Urgent, Non‐urgent and Possibly Urgent, in an effort to help clinicians triage these referrals. keywords: edx; pandemic; patient; studies; testing cache: cord-260112-tb087txz.txt plain text: cord-260112-tb087txz.txt item: #216 of 449 id: cord-260605-smkr7b15 author: Vestby, Lene K. title: Bacterial Biofilm and its Role in the Pathogenesis of Disease date: 2020-02-03 words: 12146 flesch: 35 summary: Mucoid colonies are only found in patients with chronic biofilm infection and alginate from mucoid colonies is therefore a biofilm-specific antigen. Mucoid colonies are only found in patients with chronic biofilm infection and alginate from mucoid colonies is therefore a biofilm-specific antigen. keywords: associated; aureus; bacteria; biofilm; cells; chronic; disease; formation; infections; mastitis; media; microscopy; model; otitis; pathogenesis; patients; presence; studies cache: cord-260605-smkr7b15.txt plain text: cord-260605-smkr7b15.txt item: #217 of 449 id: cord-262127-zpt0kamn author: Hussaindeen, Jameel Rizwana title: Accommodative Insufficiency: Prevalence, Impact and Treatment Options date: 2020-09-11 words: 7285 flesch: 37 summary: This study recommended that minimum amounts of near addition would be beneficial in restoring accommodation amplitudes to a level enabling near visual activities with the therapeutic lenses, yet creating a small residual blur adequate enough to stimulate and exercise accommodation. What remains unclear in all these studies is the sustainability of the DovePress restoration of accommodation amplitudes after discontinuation of the therapeutic lenses, and the duration required for the continuation and cessation of treatment. keywords: accommodation; age; children; insufficiency; prevalence; sample; studies; study; symptoms; therapy; treatment; vision cache: cord-262127-zpt0kamn.txt plain text: cord-262127-zpt0kamn.txt item: #218 of 449 id: cord-262164-cxs5xgvv author: Ackerman, Joshua M. title: What people believe about detecting infectious disease using the senses date: 2020-10-19 words: 9059 flesch: 41 summary: Beliefs about sensory use also varied depending on the specific feature being examined, with different patterns of sensory beliefs associated with evaluation of pathogenic danger than with evaluation of desirability and fit with normative standards. In Study 3, we examined whether patterns of sensory beliefs were specific to the target of evaluation (e.g., people, food), or if perceivers express different patterns of belief depending on the type of evaluation being made (e.g., pathogenic danger, fit with normative standards, desirability), even when the target is the same. keywords: beliefs; disease; effectiveness; food; participants; pathogen; people; senses; sight; study; taste; use cache: cord-262164-cxs5xgvv.txt plain text: cord-262164-cxs5xgvv.txt item: #219 of 449 id: cord-262345-hti1jjpn author: Eddy, Lucy H. title: The validity and reliability of observational assessment tools available to measure fundamental movement skills in school-age children: A systematic review date: 2020-08-25 words: 8738 flesch: 45 summary: A systematic review was required to document the psychometric properties of the observational assessment tools being promoted as measures of FMS to allow schools and health practitioners to make informed decisions about FMS assessment tools. The aim of the review was to evaluate the psychometric properties of observational FMS assessment tools for school-age children. keywords: assessment; children; evidence; fms; motor; movement; psychometric; reliability; results; studies; study; test; tools; validity cache: cord-262345-hti1jjpn.txt plain text: cord-262345-hti1jjpn.txt item: #220 of 449 id: cord-262442-kjgpriow author: Scalia, Santo title: Quercetin solid lipid microparticles: A flavonoid for inhalation lung delivery date: 2013-05-13 words: 5535 flesch: 45 summary: Quercetin microparticles were prepared by o/w emulsification via a phase inversion technique, using tristearin as the lipid component and phosphatidylcholine as an emulsifier. Results showed that quercetin SLMs could be formulated as dry powder suitable for inhalation drug delivery (20.5 ± 3.3% fine particle fraction ⩽4.46 μm) that was absorbed, via a linear kinetic model across the Calu-3 monolayer (22.32 ± 1.51% over 4 h). keywords: calu-3; cells; delivery; drug; et al; lipid; min; particle; powder; quercetin; size; slms; studies; study; transport; tristearin cache: cord-262442-kjgpriow.txt plain text: cord-262442-kjgpriow.txt item: #221 of 449 id: cord-262637-crqw59k1 author: Kwon, Sophia title: Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Protocol: A Randomized Clinical Trial date: 2020-09-09 words: 5661 flesch: 42 summary: The website will also facilitate study activities during the intervention period. Table 1 includes descriptions of both the inclusion and exclusion criteria that we will use to qualify potential study participants. keywords: analysis; bmi; care; disease; group; health; intervention; participants; study; subjects; table; weight; wtc cache: cord-262637-crqw59k1.txt plain text: cord-262637-crqw59k1.txt item: #222 of 449 id: cord-262780-ilu5oskk author: Sattui, Sebastian E. title: Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19 date: 2020-08-11 words: 4658 flesch: 42 summary: Further studies assessing HCQ with or without AZM on QT prolongation in COVID-19 patients emerged [35] . Although the observational design had limitations, it's release was followed by articles in the press highlighting concerns of harm with HCQ use [40] . keywords: coronavirus; covid-19; data; drug; hcq; hydroxychloroquine; patients; public; study; treatment; trial; use cache: cord-262780-ilu5oskk.txt plain text: cord-262780-ilu5oskk.txt item: #223 of 449 id: cord-263322-y4htkvux author: Yang, Jun title: Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis date: 2019-05-14 words: 4423 flesch: 41 summary: The full texts of 83 articles were assessed, amongst which studies were excluded for the following reasons: the control group did not receive steroid therapy (26); reviews (8); non-SNP-related studies (5); basic studies (3); studies without frequencies or effect size results (2); non-steroid-related ONFH studies (2); case reports (2); microRNA-related studies (2); duplicated reports (2); and heredity SONFH study (1) . Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group Meta-analysis of epidemiologic dose-response data Efficacy of glucocorticoids in rodents of severe acute pancreatitis: a meta-analysis Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses The SNP rs931794 in 15q25.1 is associated with lung cancer risk: a hospital-based case-control study and meta-analysis Sleep duration and the risk of osteoporosis amongst middle-aged and elderly adults: a dose-response meta-analysis Generalized least squares for trend estimation of summarized dose-response data Polymorphisms in the glucocorticoid receptor gene and associations with glucocorticoid-induced avascular osteonecrosis of the femoral head Influence of BCL2L11 polymorphism on osteonecrosis during treatment of childhood acute lymphoblastic leukemia Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia The correlation between apolipoprotein gene polymorphisms and steroid-induced osteonecrosis of the femoral head Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population MDR1 gene polymorphisms are associated with glucocorticoid-induced avascular necrosis of the femoral head in a Chinese population Association of apolipoprotein A5 genetic polymorphisms with steroid-induced osteonecrosis of femoral head in a Chinese Han population Relationship between apolipoprotein B gene polymorphism and tendon-vessel stagnation syndrome of steroid induced osteonecrosis of the femoral head Genetic polymorphisms in plasminogen activator inhibitor-1 predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese population Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population Association between polymorphisms of steroid induced osteonecrosis of the femoral head and traditional Chinese medicine syndrome types Relationship between gene polymorphisms and syndrome types in steroid-induced femoral head osteonecrosis Relationship between gene polymorphisms and hereditary susceptibility of steroid-induced femoral head osteonecrosis in Linyi City of Shandong Province Polymorphism in the PAI-1 (SERPINE1) gene and the risk of osteonecrosis in children with acute lymphoblastic leukemia Incidence of genetic polymorphisms involved in lipid metabolism amongst Chinese patients with osteonecrosis of the femoral head Genetic susceptibility of corticosteroid-induced osteonecrosis of femoral head Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group Roles of TNF-alpha gene polymorphisms in the occurrence and progress of SARS-Cov infection: a case-control study Genetic association of a polymorphism of the cAMP-responsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation MDR1(ABCB1) gene polymorphisms associated with steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus Low molecular weight phenotype of Apo(a) is a risk factor of corticosteroid-induced osteonecrosis of the femoral head after renal transplant ApoB C7623T polymorphism predicts risk for steroid-induced osteonecrosis of the femoral head after renal transplantation Thrombophilia and avascular necrosis of femoral head in kidney allograft recipients Association of corticosteroids and factor V, prothrombin, and MTHFR gene mutations with avascular osteonecrosis in renal allograft recipients Pharmacogenetic risk factors for osteonecrosis of the hip amongst children with leukemia Relationship between postrenal transplant osteonecrosis of the femoral head and gene polymorphisms related to the coagulation and fibrinolytic systems in Japanese subjects Genetic analysis of steroid-induced osteonecrosis of the femoral head ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation Association of plasminogen activator inhibitor-1 genotype with avascular osteonecrosis in steroid-treated renal allograft recipients Lipid transporter activity-related genetic polymorphisms are associated with steroid-induced osteonecrosis of the femoral head: an updated meta-analysis based on the GRADE guidelines VEGF, eNOS, and ABCB1 genetic polymorphisms may increase the risk of osteonecrosis of the femoral head Avascular necrosis of bone after cardiac transplantation. keywords: analysis; dose; head; mutation; osteonecrosis; risk; sonfh; steroid; studies cache: cord-263322-y4htkvux.txt plain text: cord-263322-y4htkvux.txt item: #224 of 449 id: cord-264079-u0nkjexi author: Murphy, Dianne title: The use of gowns and masks to control respiratory illness in pediatric hospital personnel date: 1981-11-30 words: 2677 flesch: 51 summary: Bastin R: Maladies infectieuses Acquisition of parainfluenza 3 virus infection by hospitalized children Nosocomial respiratory syncytial virus infections Control of nosocomial respiratory syncytial viral infections Respiratory syncytial virus infection in adults The immunologic response to respiratory syncytial virus infection in infants Rapid virus diagnosis: Application of immunoftuorescence Clinical and immunological response of infants and children to administration of low temperature adapted respiratory syncytial virus Diagnostic procedures for viral & rickettsial infections Modes of spread of respiratory syncytial virus (RSV) Handto-hand transmission of rhinovirus colds The study took place in February and March of 1979, when RSV infections were widespread and influenza A/USSR virus was also present in the community. keywords: illness; infants; infections; personnel; rsv; study; virus cache: cord-264079-u0nkjexi.txt plain text: cord-264079-u0nkjexi.txt item: #225 of 449 id: cord-264133-yj100ryt author: Anderson, Gregory S. title: Peer Support and Crisis-Focused Psychological Interventions Designed to Mitigate Post-Traumatic Stress Injuries among Public Safety and Frontline Healthcare Personnel: A Systematic Review date: 2020-10-20 words: 6347 flesch: 34 summary: The electronic yield of records was supplemented with hand searches of the reference lists of included studies, with selected articles searched in Google Scholar. There were 9 of 14 studies rated at a low risk of bias regarding the assessment of study outcomes based on the use of secure organizational records (e.g., rates of sickness absence and suicide) or empirically-validated mental disorder screening tools. keywords: health; post; ppte; psp; review; risk; stress; studies; study; support cache: cord-264133-yj100ryt.txt plain text: cord-264133-yj100ryt.txt item: #226 of 449 id: cord-265139-x7g3jcjm author: Zaiou, Mohamed title: The Emerging Role and Promise of Circular RNAs in Obesity and Related Metabolic Disorders date: 2020-06-16 words: 8185 flesch: 34 summary: This assumption was based on the observation that treatment of differentiated primary mouse subcutaneous adipocytes with soluble tumor necrosis factor (TNF)-α led to significant reduction in circRNAs expression [80] . In this study, thousands of adipose circRNAs were identified to be regulated during adipogenesis. keywords: adipogenesis; adipose; circrnas; diseases; expression; function; human; inflammation; insulin; metabolic; obesity; potential; protein; role; studies; tissue cache: cord-265139-x7g3jcjm.txt plain text: cord-265139-x7g3jcjm.txt item: #227 of 449 id: cord-265299-oovkoiyj author: Hickman, D.L. title: Commonly Used Animal Models date: 2016-11-25 words: 14970 flesch: 49 summary: Throughout history, outbreaks of bubonic plague, typhus, and hantaviruses have had an unwitting accomplice in the rat (Zinsser, 1935; Benedictow, 2004; Firth et al., 2014) . Over the centuries, rats have also been used for food (e.g., in Imperial China), companionship, and sport (Gorn and Goldstein, 2004; Hopkins et al., 2004; Burt, 2006) . keywords: amphibians; animals; behavior; birds; body; cage; care; couto; development; disease; enrichment; et al; example; female; fig; food; glands; housing; laboratory; male; mice; model; mouse; rabbits; rats; reptiles; research; rodents; sohn; species; studies; system; water; zebrafish cache: cord-265299-oovkoiyj.txt plain text: cord-265299-oovkoiyj.txt item: #228 of 449 id: cord-265605-32gy8w8b author: Matthews, Michael title: Development of a psychosocial intervention to support informal caregivers of people with end-stage kidney disease receiving haemodialysis date: 2020-10-01 words: 5005 flesch: 41 summary: The findings of the study will be presented at the workshop which will explore and discuss the potential key components of a psychosocial intervention for informal renal carers taking into account the information obtained from the semistructured and focus group interviews. key: cord-265605-32gy8w8b authors: Matthews, Michael; Reid, Joanne; McKeaveney, Clare; Mullan, Robert; Bolton, Stephanie; Hill, Christopher; Noble, Helen title: Development of a psychosocial intervention to support informal caregivers of people with end-stage kidney disease receiving haemodialysis date: 2020-10-01 journal: BMC Nephrol DOI: 10.1186/s12882-020-02075-2 sha: doc_id: 265605 cord_uid: 32gy8w8b BACKGROUND: Patients with end-stage kidney disease, receiving haemodialysis rely increasingly on informal carers to help manage their debilitating chronic disease. keywords: caregivers; carers; disease; haemodialysis; kidney; patients; research; stage; study cache: cord-265605-32gy8w8b.txt plain text: cord-265605-32gy8w8b.txt item: #229 of 449 id: cord-265723-6k8196p2 author: Yu, Chengjun title: Evaluation of safety, efficacy, tolerability, and treatment-related outcomes of type I interferons for Human coronaviruses (HCoVs) infection in clinical practice: An updated critical systematic review and meta-analysis date: 2020-06-25 words: 2628 flesch: 33 summary: The study designs, treatment strategies, and outcomes of included studies for evaluation of safety, efficacy, tolerability, and treatment-related outcomes of interferon for coronavirus infection in clinical practice The severe acute respiratory syndrome Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study. Clinical microbiology and infection : the official publication of the Clinical outcomes of current medical approaches for Middle East respiratory syndrome: A systematic review and meta-analysis Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia A Novel Coronavirus from Patients with Pneumonia in China Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission Middle East respiratory syndrome coronavirus in children Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection A hospital outbreak of severe acute respiratory syndrome in Guangzhou Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs Ribavirin and interferon-beta synergistically inhibit SARSassociated coronavirus replication in animal and human cell lines Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment Treatment with interferon-α2b and ribavirin improves outcome in None. keywords: coronavirus; ifn; patients; studies; study; treatment; type cache: cord-265723-6k8196p2.txt plain text: cord-265723-6k8196p2.txt item: #230 of 449 id: cord-266031-tlrsco40 author: Haghani, Milad title: Covid-19 pandemic and the unprecedented mobilisation of scholarly efforts prompted by a health crisis: Scientometric comparisons across SARS, MERS and 2019-nCoV literature date: 2020-09-21 words: 8002 flesch: 43 summary: Covid-19 studies seem to have been disseminated across a broader variety of journals and across a more diverse range of subject areas. Covid-19 studies also display the involvement of authors from a broader variety of countries compared to SARS and MERS. keywords: cluster; coronavirus; covid-19; items; journal; literature; mers; number; publications; research; sars; studies cache: cord-266031-tlrsco40.txt plain text: cord-266031-tlrsco40.txt item: #231 of 449 id: cord-266294-ua22udlc author: Koch, Oliver title: 29 Antiviral drugs date: 2010-12-31 words: 10818 flesch: 39 summary: Metabolism The hemochromatosis gene polymorphism HFE 187C> G and possibly mitochondrial haplogroup J gave relative protection against lipoatrophy during antiretroviral drug therapy in a trial in which 96 patients were randomized to didanosine þ stavudine or zidovudine þ lamivudine, combined with efavirenz and/ or nelfinavir in AIDS Clinical Trials Group (ACTG) 384 sub-study A5005s (20 C ). The use of isoniazid preven tive therapy during antiretroviral drug therapy did not increase the risk of hepatotoxicity. keywords: abacavir; combination; dose; drug; efavirenz; hepatitis; hiv; lamivudine; nevirapine; patients; ribavirin; ritonavir; stavudine; study; tenofovir; therapy; tipranavir; treatment; women; zidovudine cache: cord-266294-ua22udlc.txt plain text: cord-266294-ua22udlc.txt item: #232 of 449 id: cord-267006-gsevwptc author: Waltz, Jeffrey title: Improving CT-Derived Fractional Flow Reserve Analysis: A Quality Improvement Initiative date: 2020-10-07 words: 2602 flesch: 36 summary: When the issues were brought to their attention and they were subsequently given training, this likely controlled for many confounders that were problematic in FFRCT analysis acceptance rate and CCTA quality. produced as well as the overall acceptance of CCTA studies for FFRCT analysis. keywords: analysis; ccta; coronary; ffrct; quality; rate; studies cache: cord-267006-gsevwptc.txt plain text: cord-267006-gsevwptc.txt item: #233 of 449 id: cord-267076-a4ulg4ck author: Mechili, Enkeleint A. title: Is the mental health of young students and their family members affected during the quarantine period? Evidence from the COVID‐19 pandemic in Albania. date: 2020-07-13 words: 4027 flesch: 55 summary: In comparison to other studies in student populations which used the PHQ-9 questionnaire, our study reported much higher depression levels (Kim et. al., 2019; Du et. al., 2017; Karekla et. Higher scores indicated higher depression levels (0-4 indicates minimal depression levels, 5-9 mild depression levels, 10-14 moderate depression levels, 15-19 moderate-severe depression levels and 20-27 severe depression levels). keywords: depression; family; health; students; study cache: cord-267076-a4ulg4ck.txt plain text: cord-267076-a4ulg4ck.txt item: #234 of 449 id: cord-267132-nb0j6k3h author: Loveday, H.P. title: epic3: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England date: 2013-12-10 words: 43426 flesch: 35 summary: Appropriateness of use of indwelling urinary catheters in patients admitted to the medical service Overuse of the indwelling urinary tract catheter in hospitalized medical patients Trends in catheter-associated urinary tract infections in adult intensive care units -United States Clinical and economic consequences of nosocomial catheter-related bacteriuria Recognition and prevention of healthcare-associated urinary tract infections in the intensive care unit Epidemiology of hospital-acquired urinary tract-related bloodstream infection at a university hospital Silver alloy vs. uncoated urinary catheters: a systematic review of the literature Catheter-associated urinary tract infections: new aspects of novel urinary catheters A review of strategies to decrease the duration of indwelling urethral catheters and potentially reduce the incidence of catheter-associated urinary tract infections Enhancing the safety of critically ill patients by reducing urinary and central venous catheterrelated infections Comparison of urethral reaction to full silicone, hydrogen-coated and siliconised latex catheters Effect of catheter material on the incidence of urethral strictures Randomised study of the effect of midnight versus 0600 removal of urinary catheters The association between indwelling urinary catheter use in the elderly and urinary tract infection in acute care Aiming to reduce catheter associated urinary tract infections (CAUTI) by adopting a checklist and bundle to achieve sustained system improvements Evidence for the use of silver-alloycoated urethral catheters The high impact actions for nursing and midwifery 5: protection from infection Preventing catheter-related bacteriuria: should we? How? Epidemiology of urinary tract infections: incidence, morbidity, and economic costs Guideline for prevention of catheter-associated urinary tract infections Computerbased order entry decreases duration of indwelling urinary catheterization in hospitalized patients Effect of nurse-led multidisciplinary rounds on reducing the unnecessary use of urinary catheterization in hospitalized patients Systematic review and S58 meta-analysis: reminder systems to reduce catheter-associated urinary tract infections and urinary catheter use in hospitalized patients Stop orders to reduce inappropriate urinary catheterization in hospitalized patients: a randomized controlled trial Reduction of urinary tract infection and antibiotic use after surgery: a controlled, prospective, before-after intervention study Interventions to minimise the initial use of indwelling urinary catheters in acute care: a systematic review Non-invasive measurement of bladder volume as an indication for bladder catheterization after orthopaedic surgery and its effect on urinary tract infections A collaborative, nurse-driven initiative to reduce hospital-acquired urinary tract infections Prevention of nosocomial catheter-associated urinary tract infections through computerized feedback to physicians and a nurse-directed protocol Continence clinic. keywords: access; alcohol; analysis; bsi; care; catheter; catheter insertion; contamination; control; devices; effectiveness; evidence; gloves; guidelines; hand; hand hygiene; healthcare; healthcare workers; hospital; hygiene; identià; infection; insertion; interventions; meta; microorganisms; number; patients; prevention; removal; review; risk; safety; sharps; signià; site; skin; studies; study; systematic; term; use; venous; workers cache: cord-267132-nb0j6k3h.txt plain text: cord-267132-nb0j6k3h.txt item: #235 of 449 id: cord-267389-v2ihhtl0 author: Canevelli, Marco title: The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 Outbreak date: 2020-09-24 words: 3094 flesch: 34 summary: However, it also represents a repository for the vast majority of clinical trial protocols conducted worldwide. The following data were abstracted by three authors (F.T., Ga.R., and Gi.R.) from the selected protocols: NCT (the unique identification code assigned by clinicaltrials.gov) and/or EudraCT codes; study phase; allocation and masking procedures; tested compound(s); way of administration; mechanism of action; primary outcome measure(s); expected primary completion date; expected number of participants; age range of participants; targeted COVID-19 related condition; sponsor; and location. keywords: covid-19; phase; protocols; studies; trials cache: cord-267389-v2ihhtl0.txt plain text: cord-267389-v2ihhtl0.txt item: #236 of 449 id: cord-267608-0odu8lus author: Chen, Daohong title: Innovative highlights of clinical drug trial design date: 2020-06-03 words: 4167 flesch: 23 summary: Clinical trial plays an indispensable role in evaluating efficacy and safety of therapeutic agents prior to marketing for human use, and has been constantly co-evolving along with the dynamic interactions between cutting-edge scientific discoveries and regulatory policy updating [2, 3] . In this light, the article herein highlights an array of outstanding developments in the perspective of drug trial design, being corroborated by notable successes in the clinical settings. keywords: clinical; development; disease; drug; efficacy; orphan; patients; phase; study; trial cache: cord-267608-0odu8lus.txt plain text: cord-267608-0odu8lus.txt item: #237 of 449 id: cord-268088-y4vg7frb author: Montané, Xavier title: Current Perspectives of the Applications of Polyphenols and Flavonoids in Cancer Therapy date: 2020-07-23 words: 11135 flesch: 39 summary: Several research groups have proved the cytotoxicity of kaempferol against breast cancer cells both in vitro and in vivo: -By inhibiting the growth of cancer cells, Flavonols are a class of flavonoids based on the backbone 3-hydroxyflavone. Several research groups have proved the cytotoxicity of kaempferol against breast cancer cells both in vitro and in vivo: -By inhibiting the growth of cancer cells, -By stopping the progression and proliferation of cancer cells, and -By inducing cancer cells apoptosis. keywords: acid; activity; anticancer; apigenin; apoptosis; breast; breast cancer; cancer; cancer cells; compounds; drug; effects; flavonoids; honokiol; plants; polyphenols; properties; resveratrol; therapy cache: cord-268088-y4vg7frb.txt plain text: cord-268088-y4vg7frb.txt item: #238 of 449 id: cord-268149-narre5e7 author: Aziz, Muhammad Abdul title: Traditional uses of medicinal plants used by Indigenous communities for veterinary practices at Bajaur Agency, Pakistan date: 2018-01-29 words: 8420 flesch: 45 summary: A case study among indigenous adolescents in Oaxaca Schooling and local environmental knowledge: do they complement or substitute each other Secular changes of indigenous knowledge of useful plants: separating age and cohort effects Modernization and medicinal plant knowledge in a Caribbean horticultural village Pharmaceutical ethnobotany in the Montseny biosphere reserve (Catalonia, Iberian Peninsula). Current study revealed that the study area has sufficient knowledge on ethnoveterinary medicinal plants. keywords: agency; animals; area; communities; diseases; ethnoveterinary; health; knowledge; leaves; livestock; pakistan; people; plants; practices; problems; species; study; use; uses cache: cord-268149-narre5e7.txt plain text: cord-268149-narre5e7.txt item: #239 of 449 id: cord-268417-6eyetb5i author: Mandel, Benjamin title: Neutralization of Animal Viruses date: 1978-12-31 words: 23029 flesch: 41 summary: Subsequent studies (Rowlands et al., 1971 ) revealed that the antigens located at the vertexes were involved in stimulating the production of neutralizing antibody. Recently, Cavan-agh et al. (1977) reported that the VP, capsid polypeptide of FMD virus induced neutralizing antibody. keywords: activity; animal; antibodies; antibody; antiserum; binding; complement; complex; complexes; et al; fab; fraction; igg; interaction; mandel; neutralization; neutralizing; rabbit; rate; reaction; sera; serum; studies; viral; virus; viruses cache: cord-268417-6eyetb5i.txt plain text: cord-268417-6eyetb5i.txt item: #240 of 449 id: cord-269015-850bvb9t author: Östlund, Ulrika title: Combining qualitative and quantitative research within mixed method research designs: A methodological review date: 2011-03-31 words: 8456 flesch: 25 summary: This paper explores the analytical approaches (i.e. parallel, concurrent or sequential) used in mixed methods studies within healthcare and exemplifies the use of triangulation as a methodological metaphor for drawing inferences from qualitative and quantitative findings originating from such analyses. The use of the methodological metaphor of triangulation on convergent, complementary, and divergent results from mixed methods studies is exemplified and an example of developing theory from such data is provided. keywords: analysis; approach; care; data; findings; health; metaphor; methods; methods research; methods studies; research; studies; study; triangulation cache: cord-269015-850bvb9t.txt plain text: cord-269015-850bvb9t.txt item: #241 of 449 id: cord-269343-qwgmn06t author: Livingston, Gill title: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission date: 2020-07-30 words: 23202 flesch: 38 summary: A systematic review Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife Computerized cognitive training in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis Everyday impact of cognitive interventions in mild cognitive impairment: a systematic review and meta-analysis Preventing cognitive decline in Black individuals with mild cognitive impairment: a randomized clinical trial Association of age-related hearing loss with cognitive function, cognitive impairment, and dementia: a systematic review and meta-analysis Association of subclinical hearing loss with cognitive performance Association of midlife hearing impairment with late-life temporal lobe volume loss Death, depression, disability, and dementia associated with self-reported hearing problems: a 25-year study Association of cognition and age-related hearing impairment in the English longitudinal study of ageing Longitudinal relationship between hearing aid use and cognitive function in older Americans Induction of a transmissible tau pathology by traumatic brain injury ApoE4-associated phospholipid dysregulation contributes to development of tau hyper-phosphorylation after traumatic brain injury The epidemiology of traumatic brain injury: a review Long-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study Traumatic brain injury and the risk of dementia diagnosis: a nationwide cohort study Head or brain injuries and Alzheimer's disease: a nested case-control register study Association of mild traumatic brain injury with and without loss of consciousness with dementia in US military veterans Military-related risk factors in female veterans and risk of dementia Association between statin use and risk of dementia after a concussion Chronic traumatic encephalopathy -confusion and controversies Neurodegenerative disease mortality among former professional soccer players Association of ideal cardiovascular health with vascular brain injury and incident dementia Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study Association of midlife to latelife blood pressure patterns with incident dementia Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged ≥75 years: a randomized clinical trial Effect of intensive vs standard blood pressure control on probable dementia: a randomized clinical trial Prevention of cognitive impairment with intensive systolic blood pressure control Blood pressure and dementia: what the SPRINT-MIND trial adds and what we still need to know Diuretic antihypertensive drugs and incident dementia risk: a systematic review, meta-analysis and meta-regression of prospective studies Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies Calcium channel blocker use reduces incident dementia risk in elderly hypertensive patients: a meta-analysis of prospective studies An investigation of antihypertensive class, dementia, and cognitive decline: a metaanalysis Statins for the prevention of dementia Effect of aspirin on disability-free survival in the healthy elderly Risk factors associated with the onset and progression of Alzheimer's disease: a systematic review of the evidence Midlife physical activity, psychological distress, and dementia risk: the HUNT study Midlife cardiovascular fitness and dementia: a 44-year longitudinal population study in women Physical inactivity, cardiometabolic disease, and risk of dementia: an individualparticipant meta-analysis Association of leisure-time physical activity across the adult life course with all-cause and cause-specific mortality Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis The effectiveness of physical exercise on cognitive and psychological outcomes in individuals with mild cognitive impairment: a systematic review and metaanalysis Exercise training for preventing dementia, mild cognitive impairment, and clinically meaningful cognitive decline: a systematic review and meta-analysis Sex differences in exercise efficacy to improve cognition: a systematic review and meta-analysis of randomized controlled trials in older humans Risk reduction of cognitive decline and dementia: WHO guidelines. We evaluated new evidence on dementia risk in LMIC; risks and protective factors for dementia; detection of Alzheimer's disease; multimorbidity in dementia; and interventions for people affected by dementia. keywords: age; alzheimer; amyloid; analysis; brain; care; cognition; cohort; decline; dementia; dementia risk; disease; education; effect; evidence; follow; health; hearing; impairment; intervention; life; meta; people; population; review; risk; risk factors; studies; study; symptoms; tbi; use; years cache: cord-269343-qwgmn06t.txt plain text: cord-269343-qwgmn06t.txt item: #242 of 449 id: cord-269373-d5xam4kb author: Schumacher, J. title: The impact of respiratory protective equipment on difficult airway management: a randomised, crossover, simulation study date: 2020-05-28 words: 1387 flesch: 33 summary: This is the first study comparing the impact of modern powered respirators and standard respirators on simulated difficult airway procedures. Although they are bulkier and more expensive, powered respirators eliminate the need for fit testing and problems of heat build-up, dead-space ventilation and airflow resistance keywords: airway; management; protection; respirators; study cache: cord-269373-d5xam4kb.txt plain text: cord-269373-d5xam4kb.txt item: #243 of 449 id: cord-271573-qsr3ka5p author: Schafer, Austin title: Telemedicine in Pediatric Otolaryngology: Ready for Prime Time? date: 2020-09-24 words: 3809 flesch: 45 summary: As specialized physical exams are needed to make many ENT diagnoses, there has been concern over the diagnostic reliability of telemedicine technology. The authors explain that a single otolaryngologist was responsible for responding to the influx of telemedicine consultations on a given day, and that this responsibility rotated daily. keywords: covid-19; otolaryngology; parents; patients; study; technology; telemedicine cache: cord-271573-qsr3ka5p.txt plain text: cord-271573-qsr3ka5p.txt item: #244 of 449 id: cord-272901-dsnbh4t1 author: Dew, Jeffrey title: Ten Years of Marriage and Cohabitation Research in the Journal of Family and Economic Issues date: 2020-10-22 words: 6920 flesch: 42 summary: Further, given that the studies that tested the association between financial issues and relationship quality averaged almost one per year may suggest that this area of relationship quality research continues to possess importance. From my previous experience, I knew that studies often focus on financial issues and family structure issues (e.g., the financial consequences of divorce). keywords: association; couples; family; issues; marital; marriage; quality; relationship; studies; study cache: cord-272901-dsnbh4t1.txt plain text: cord-272901-dsnbh4t1.txt item: #245 of 449 id: cord-274305-mnyy41po author: Kumar, Purnima S title: Demystifying the mist: Sources of microbial bioload in dental aerosols date: 2020-07-27 words: 5945 flesch: 32 summary: In an attempt to establish context for reviewing the literature on dental aerosols, we begin this review by examining the reasons why definitions of aerosols vary widely. The vectors can be natural, namely, mist, fog, and vapor or anthropogenic, for example, smoke, dust, smog, and of particular importance to us, dental aerosol. keywords: aerosol; air; evidence; human; microbial; oral; particles; pathogens; procedures; saliva; studies; transmission; viruses cache: cord-274305-mnyy41po.txt plain text: cord-274305-mnyy41po.txt item: #246 of 449 id: cord-274597-a67u1elx author: Röseler, Lukas title: Evidence against subliminal anchoring: Two close, highly powered, preregistered, and failed replication attempts date: 2020-10-16 words: 7392 flesch: 52 summary: Both studies found subliminal anchoring effects. Study 2 showed that participants could not recognize subliminal anchors even when participants knew the anchors existed and wanted to recognize them. keywords: anchoring; effect; mussweiler; participants; studies; study; time cache: cord-274597-a67u1elx.txt plain text: cord-274597-a67u1elx.txt item: #247 of 449 id: cord-274802-7ioiwsd8 author: Varghese, Praveen Mathews title: Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies date: 2020-08-19 words: 19710 flesch: 31 summary: Unlike SARS, COVID-19 patients had the highest viral load near presentation, which could account for the fast-spreading nature of this epidemic. In a study involving COVID-19 patients in Hong Kong recorded high viral load on presentation with the onset of symptoms and also when the symptoms are mild (83) . keywords: activation; acute; antibodies; case; cells; china; complement; coronavirus; cov-2; covid-19; covid-19 patients; disease; dose; drug; high; human; infection; inflammation; injury; levels; novel; pathogenesis; patients; plasma; pneumonia; protein; response; sars; spike; studies; study; syndrome; system; transmission; treatment; trial; vaccine cache: cord-274802-7ioiwsd8.txt plain text: cord-274802-7ioiwsd8.txt item: #248 of 449 id: cord-275340-q8d7rvnj author: Sun, JingKang title: Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19 date: 2020-06-21 words: 6638 flesch: 44 summary: In a randomized clinical trial from Wuhan about HCQ treatment of mild COVID-19 [50] , 31 out of 62 patients received HCQ (200 mg/2 times/day for 5 days). In the initial trial from France, of the 84 patients receiving HCQ treatment, 8 patients discontinued HCQ owing to ECG modifications within 4 days. keywords: activity; azithromycin; coronavirus; cov-2; covid-19; group; hcq; patients; results; sars; studies; study; treatment cache: cord-275340-q8d7rvnj.txt plain text: cord-275340-q8d7rvnj.txt item: #249 of 449 id: cord-276015-id15u3br author: Beran, Jiří title: Inosine pranobex is safe and effective for the treatment of subjects with confirmed acute respiratory viral infections: analysis and subgroup analysis from a Phase 4, randomised, placebo-controlled, double-blind study date: 2016-11-07 words: 6094 flesch: 41 summary: Thus, the efficacy of inosine pranobex was improved in nonobese subjects compared with obese subjects, probably because the immune system in the former is more capable of defending against pathogens and is not negatively affected by obesity-related complications. The safety analysis demonstrated that inosine pranobex treatment was well tolerated, and no major differences in safety profiles were observed between treatment groups. keywords: age; group; influenza; inosine; inosine pranobex; placebo; pranobex; study; subjects; treatment; years cache: cord-276015-id15u3br.txt plain text: cord-276015-id15u3br.txt item: #250 of 449 id: cord-276327-wyevh4xv author: Sheng, Calvin C title: Canakinumab to reduce deterioration of cardiac and respiratory function in SARS‐CoV‐2 associated myocardial injury with heightened inflammation (canakinumab in Covid‐19 cardiac injury: The three C study) date: 2020-08-24 words: 3243 flesch: 27 summary: Coronavirus disease 2019 (COVID-19): situation report Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Clinical characteristics of Covid-19 in New York city Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Compassionate use of remdesivir for patients with severe Covid-19 Remdesivir for the treatment of Covid-19 -preliminary report Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and lifethreatening COVID-19: a randomized clinical trial Dexamethasone in hospitalized patients with Covid-19 -preliminary report COVID-19 and the cardiovascular system Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Community-Acquired Pneumonia-China Network. Association between cardiac injury and mortality in hospitalized patients infected with avian influenza a (H7N9) virus Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan China Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Prognostic value of NT-proBNP in patients with severe COVID-19 Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) COVID-19: consider cytokine storm syndromes and immunosuppression. keywords: canakinumab; cardiac; clinical; covid-19; inflammation; injury; patients; study; trial cache: cord-276327-wyevh4xv.txt plain text: cord-276327-wyevh4xv.txt item: #251 of 449 id: cord-276711-y74zr7fn author: Winthrop, Kevin L title: To immunosuppress: whom, when and how? That is the question with COVID-19 date: 2020-08-04 words: 2456 flesch: 35 summary: We anxiously await the conclusion of ongoing sarilumab and tocilizumab studies, as presently it is unclear who might benefit, and when, from IL-6 inhibition. The authors explicitly and elegantly discuss the potential for such unmeasured confounding, acknowledge the limitations of observational studies and conducted a number of sensitivity analyses to mitigate these concerns. keywords: covid-19; mortality; patients; studies; study; tocilizumab cache: cord-276711-y74zr7fn.txt plain text: cord-276711-y74zr7fn.txt item: #252 of 449 id: cord-276896-14zq3tln author: Vaz, Manjulika title: Public perceptions on Controlled Human Infection Model (CHIM) studies—a qualitative pilot study from South India date: 2020-10-21 words: 9351 flesch: 45 summary: Since CHIM research studies have yet to begin in India, it presents an opportunity to do things differently this time around, creating guidelines, processes and infrastructure in a transparent and inclusive manner, to dispel apprehensions born of past clinical trials, and advance vaccine science in a sustainable, safe and cost-effective manner. Council for International Organizations of Medical Sciences (CIOMS) Grounded theory research: Procedures, canons, and evaluative criteria Conducting controlled human infection model studies in India is an ethical obligation It takes a village: medical research and ethics in Mali Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders' meeting held in Entebbe Taking social relationships seriously: lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast Trust in healthcare: an evolving concept Controlled human infection models for vaccine development: Zika virus debate A framework for Controlled Human Infection Model (CHIM) studies in Malawi: report of a Wellcome Trust workshop on CHIM in Low Income Countries Lessons learnt from the first controlled human malaria infection study Law and ethics in consensual harm Expert voices and equal partnerships: establishing Controlled Human Infection Models (CHIMs) in Vietnam A quest for utilitarian approach in research Forms of benefit sharing in global health research undertaken in resource poor settings: a qualitative study of stakeholder's views in Kenya Katayama syndrome without Schistosoma mansoni eggs Ethical oversight of public health research: can rules and IRBs make a difference in developing countries? keywords: chim; ethics; health; human; india; infection; medical; participants; people; public; research; risk; rural; studies; study; urban cache: cord-276896-14zq3tln.txt plain text: cord-276896-14zq3tln.txt item: #253 of 449 id: cord-278246-mnj0zmkn author: Hussain, Nowair title: A Meta-Analysis on the Effects of Hydroxychloroquine on COVID-19 date: 2020-08-24 words: 2991 flesch: 49 summary: The mortality rate of patients after applying HCQ on patients with COVID-19 2) The rate of progression/improvement of COVID-19 disease 3) The rate of COVID-19 disease severity, for example, after applying the HCQ treatment, the rate of which patients went on to develop severe conditions such as acute hypoxic respiratory failure and adult respiratory distress syndrome. COVID-19 patients have increased levels of plasma pro-inflammatory cytokines and chemokines keywords: covid-19; disease; hcq; patients; rate; studies; study; treatment cache: cord-278246-mnj0zmkn.txt plain text: cord-278246-mnj0zmkn.txt item: #254 of 449 id: cord-278297-twiye6jv author: Lourenco, Stella F. title: No Participant Left Behind: Conducting Science During COVID-19 date: 2020-05-11 words: 1639 flesch: 46 summary: As excited as we are about the promises of online testing (e.g., in fields like developmental psychology where data collection is typically slow and expensive), we are also concerned about how the demographics of online participants may shift during COVID-19. J o u r n a l P r e -p r o o f Participation in online studies requires internet access, a staple among many, though not all, households. keywords: access; internet; participants; testing cache: cord-278297-twiye6jv.txt plain text: cord-278297-twiye6jv.txt item: #255 of 449 id: cord-279718-r21k0gku author: Benseler, Anouk title: Antibiotic prophylaxis for urodynamic testing in women: a systematic review date: 2020-08-26 words: 3266 flesch: 32 summary: (3261) 88 focal infect*.ti,ab,tw,kf. (2207) 89 opportunistic infect*.ti,ab,tw,kf 43540) 76 or 77 or 78 or 79 or 80 or 81 or 82 or 83 or 84 or 85 or 86 or 87 or 88 or 89 or 90 or 91 or 92 or 93 or Urological/ (838) 97 (diagnos* adj2 urolog*).ti,ab,tw,kf Urinary Catheterization/ (13829) 99 (urin* adj2 catheter*).ti,ab,tw,kf Urodynamic evaluation of the bladder and pelvic floor A study of female urinary tract infection caused by urodynamic investigation Prophylactic antibiotics after urodynamics in women: a decision analysis Bacteriuria and urinary tract infection after female urodynamic studies: risk factors and microbiological analysis Evaluation of the relationship between urodynamic examination and urinary tract infection based on urinalysis results Prevention of infection after gynecologic procedures Prophylactic antibiotics to reduce the risk of urinary tract infections after urodynamic studies 275-antibiotic prophylaxis in Gynaecologic procedures Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention Systematic reviews: CRD's guidance for undertaking reviews in health care The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement The Cochrane Collaboration's tool for assessing risk of bias in randomised trials Incidence of bacteriuria after urodynamic study with or without antibiotic prophylaxis in women with urinary incontinence Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and Morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation Should we always use antibiotics after urodynamic studies in high-risk patients? Urinary tract infection after urodynamic studies in women: incidence and natural history Preoperative assessment of the patient and risk factors for infectious complications and tentative classification of surgical field contamination of urological procedures The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing The impact of prulifloxacin on vaginal lactobacillus microflora: an in vivo study Evaluation of surface micropattern (sharklet) on Foleys silicon catheter in reducing urinary tract infections Chlorhexidine for meatal cleaning in reducing catheterassociated urinary tract infections: a multicentre stepped-wedge randomised controlled trial Prevention of CAUTI: simple is beautiful Reducing catheter-associated urinary tract infections in hospitals: Study protocol for a multi-site randomised controlled study Types of urethral catheter for reducing symptomatic urinary tract infections in hospitalised adults requiring short-term catheterisation: multicentre randomised controlled trial and economic evaluation of antimicrobial-and antiseptic-impregnated urethral catheters (the CATHETER trial) Infection prevention with natural protein-based coating on the surface of Foley catheters: a randomised controlled clinical trial Effect of cranberry extract capsules taken during the perioperative period upon the post-surgical urinary infection in gynecology Adding cranberry extract to flexible cystoscopy profilaxis decreases urinary infection rates Cranberry juice concentrate does not significantly decrease the incidence of acquired bacteriuria in female hip fracture patients receiving urine catheter: a double-blind randomized trial A double-blind, randomized, controlled trial on N-acetylcysteine for the prevention of acute kidney injury in patients undergoing allogeneic hematopoietic stem cell transplantation American cranberry (proanthocyanidin 120 mg): its value for the prevention of urinary tracts infections after ureteral catheter placement Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women Cranberry capsules for reduction of bacteriuria plus pyuria in nursing home women: a randomized clinical trial Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgements We are grateful to Dr. Kellie Murphy, Vice Chair of Table 3 Medline search strategy As well, reference lists of included studies, relevant systematic reviews and clinical trial registries were reviewed. keywords: antibiotic; prophylaxis; review; studies; study; uds; uti cache: cord-279718-r21k0gku.txt plain text: cord-279718-r21k0gku.txt item: #256 of 449 id: cord-279748-ycgpqs89 author: Gremi, Téa title: COVID-19 studies registration worldwide for prospective studies with a specific focus on the fast-tracking of French ethic procedures date: 2020-06-30 words: 139 flesch: 42 summary: key: cord-279748-ycgpqs89 authors: Gremi, Téa; Ginesy, Éric; Payen, Didier; Lefrant, Jean-Yves; Marin, Benoît title: COVID-19 studies registration worldwide for prospective studies with a specific focus on the fast-tracking of French ethic procedures date: 2020-06-30 journal: Anaesth Crit Care Pain Med DOI: 10.1016/j.accpm.2020.06.010 sha: doc_id: 279748 cord_uid: ycgpqs89 nan interventional, 899 (40%) observational, 37 not classified). Figure 1 shows the number of studies registered per country; 1289 (57%) studies are still recruiting and 138 were declared completed (6%). keywords: studies cache: cord-279748-ycgpqs89.txt plain text: cord-279748-ycgpqs89.txt item: #257 of 449 id: cord-279913-lgdmlies author: Katz, D. H. title: Proteomic Profiling in Biracial Cohorts Implicates DC-SIGN as a Mediator of Genetic Risk in COVID-19 date: 2020-06-11 words: 4034 flesch: 46 summary: Further, while changes in aptamer binding are typically reflective of protein levels, it may be the case that ABO-mediated glycosylation alters aptamer binding, thus changing the measurement of the protein without a true change in protein levels. While the proteomic profiling discussed here is extensive, it does not cover the entire proteome, and important protein associations may be missed as a result. keywords: abo; covid-19; data; heart; jhs; locus; preprint; protein; risk; study cache: cord-279913-lgdmlies.txt plain text: cord-279913-lgdmlies.txt item: #258 of 449 id: cord-279935-asg71qtr author: Beasley, Lana O. title: Best Practices for Engaging Pregnant and Postpartum Women at Risk of Substance Use in Longitudinal Research Studies: a Qualitative Examination of Participant Preferences date: 2020-10-28 words: 7892 flesch: 32 summary: These findings indicate the importance of reporting potential benefits and compensation not only when recruiting participants to enroll in a research project, but also to continue this conversation to retain research participants. Research studies on substance exposures during pregnancy expanded rapidly in the past 30 years, in recognition of the cocaine epidemics of the 90s, and the current increases in prenatal opioid and methamphetamine exposures (Gabrhelík, et al. 2020) . keywords: comments; health; information; participants; participation; recruitment; research; retention; risk; studies; study; use; women cache: cord-279935-asg71qtr.txt plain text: cord-279935-asg71qtr.txt item: #259 of 449 id: cord-280111-6hiuzkvz author: Maspero, Cinzia title: Available Technologies, Applications and Benefits of Teleorthodontics. A Literature Review and Possible Applications during the COVID-19 Pandemic date: 2020-06-17 words: 6917 flesch: 41 summary: Indeed, an application for smartphones that allows remote monitoring of orthodontic patients using an algorithm of artificial intelligence, has recently been developed. The Italian Society of Orthodontics (SIDO) has recently published the recommended guidelines on the management of orthodontic patients during the COVID-19 outbreak. keywords: management; monitoring; office; patients; review; studies; study; teleassistance; teleorthodontics; time; treatment; visits cache: cord-280111-6hiuzkvz.txt plain text: cord-280111-6hiuzkvz.txt item: #260 of 449 id: cord-280373-xhvhep84 author: Faust, A. title: Challenges and proposed solutions in making clinical research on COVID-19 ethical. A status quo analysis across German research ethics committees date: 2020-08-14 words: 3665 flesch: 37 summary: Currently, there are many international contributions that address ethical issues in COVID-19 research, such as in challenge studies [16] or in high-demand trials [17] . Our status quo analysis on ethical issues based on feedback from 22 German RECs broadens our understanding of the spectrum of ethical challenges in COVID-19 research as perceived from those involved in the concrete review and oversight of COVID-19 studies. keywords: challenges; consent; covid-19; preprint; recs; research; studies cache: cord-280373-xhvhep84.txt plain text: cord-280373-xhvhep84.txt item: #261 of 449 id: cord-281051-i229xv0o author: Bishop-Williams, Katherine E. title: A protocol for a systematic literature review: comparing the impact of seasonal and meteorological parameters on acute respiratory infections in Indigenous and non-Indigenous peoples date: 2017-01-26 words: 6406 flesch: 38 summary: Globally, Indigenous peoples may experience a different burden of ARI compared to non-Indigenous peoples. The results can be presented in one of two eligible ways: (i) two models representing the Indigenous and non-Indigenous strata separately with the same seasonal or meteorological parameter in both models, producing two measures of association for which the ratio of odds ratios (ROR) can be calculated (i.e., ARI-exposure model for Indigenous peoples and ARI-exposure model for non-Indigenous peoples); or (ii) a model for an ARI outcome that includes indigeneity and seasonal or meteorological parameter(s) as independent variables from which further calculations can be made (Fig. 1) . keywords: ari; data; exposure; parameters; peoples; population; review; screening; search; studies; study cache: cord-281051-i229xv0o.txt plain text: cord-281051-i229xv0o.txt item: #262 of 449 id: cord-281877-r1y1hz4q author: Lavretsky, Helen title: Scientific Autobiography of a Spiritual Seeker in the Year of Hindsight's 20/20.: “Was I deceived, or did a sable cloud Turn forth her silver lining on the night?” John Milton “Comus” (1634) date: 2020-08-11 words: 2688 flesch: 42 summary: A greater truth about that nature of late life mood and cognitive disorders will emerge from this collaboration and will be the source for new research ideas for years to come. In the later years, new research questions originated from my clinical experience. keywords: depression; health; mind; new; research; study; yoga cache: cord-281877-r1y1hz4q.txt plain text: cord-281877-r1y1hz4q.txt item: #263 of 449 id: cord-282063-tkp1tifx author: Saberi, Parya title: Research in the Time of Coronavirus: Continuing Ongoing Studies in the Midst of the COVID-19 Pandemic date: 2020-04-18 words: 1950 flesch: 30 summary: For longitudinal research, reloadable debit cards are a convenient method of payment and have been shown to be highly feasible and acceptable by research participants [24] . In the era of pandemics, such SARS-CoV-2, there is a need to continue research activities, while keeping research participants and staff safe. keywords: adherence; health; hiv; participants; recruitment; research; study cache: cord-282063-tkp1tifx.txt plain text: cord-282063-tkp1tifx.txt item: #264 of 449 id: cord-282194-0sjmf1yn author: Cherak, Stephana J. title: Impact of social media interventions and tools among informal caregivers of critically ill patients after patient admission to the intensive care unit: A scoping review date: 2020-09-11 words: 5412 flesch: 37 summary: Ultimately, the relatively rapid evolution of social media means studies on usage will nearly exclusively reflect social media use of the past. Advances in Patient Safety Lessons Learned From Web-and Social Media-Based Educational Initiatives by Pulmonary The World Federation of Societies of Intensive and Critical Care Medicine Newsletter Online, social media and mobile technologies for psychosis treatment: a systematic review on novel user-led interventions Methods of using real-time social media technologies for detection and remote monitoring of HIV outcomes Social media use in healthcare: A systematic review of effects on patients and on their relationship with healthcare professionals Retiring the Term Futility in Value-Laden Decisions Regarding Potentially Inappropriate Medical Treatment Ethical dilemmas due to the Covid-19 pandemic Bereavement Support on the Frontline of COVID-19: Recommendations for Hospital Clinicians Rehabilitation After Critical Illness in People With COVID-19 Infection Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations We thank Dr. Diane Lorenzetti (University of Calgary) for the development of the search strategies. keywords: care; caregivers; health; media; patient; review; studies; study; use cache: cord-282194-0sjmf1yn.txt plain text: cord-282194-0sjmf1yn.txt item: #265 of 449 id: cord-282280-5pggpbrq author: Doornekamp, Laura title: Determinants of Vaccination Uptake in Risk Populations: A Comprehensive Literature Review date: 2020-08-27 words: 9968 flesch: 30 summary: In HCW, influenza vaccination uptake is most widely studied. While targeted vaccination guidelines are available, vaccination uptake seems low. keywords: analysis; association; caret; determinant; influenza; pointing; population; risk; significance; studies; uptake; vaccination; vaccination uptake cache: cord-282280-5pggpbrq.txt plain text: cord-282280-5pggpbrq.txt item: #266 of 449 id: cord-282526-b8tky324 author: Berger Gillam, T. title: Norwich COVID-19 Testing Initiative: feasibility project evaluation date: 2020-09-23 words: 2802 flesch: 51 summary: This study aimed to pilot mass COVID-19 testing on a university research park, to assess the feasibility and acceptability of scaling up to all staff and students. The study did not identify any false positives, despite this being considered a risk of universal testing (10) . keywords: covid-19; participants; population; preprint; students; study; testing; university cache: cord-282526-b8tky324.txt plain text: cord-282526-b8tky324.txt item: #267 of 449 id: cord-282783-ps5jyjkl author: None title: Full Issue PDF date: 2020-09-30 words: 15963 flesch: 33 summary: Transthyretin amyloid cardiomyopathy: JACC state-of-the-art review Natural his A new staging system for cardiac transthyretin amyloidosis Cardiovascular disease mortality after chemotherapy or surgery for testicular nonseminoma: a populationbased study Testicular cancer: a Mechanisms of cisplatin nephrotoxicity White-Paper-1.pdf A new equation to estimate glomerular filtration rate Crosstalk between vascular redox and calcium signaling in hypertension involves TRPM2 (Transient Receptor Potential Melastatin 2) cation channel Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers: smoking, thrombin, and vascular responses in vivo Intra-arterial substance P mediated vasodilatation in the human forearm: pharmacology, reproducibility and tolerability Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans Vascular effects of apelin in vivo in man The vasodilator action of nebivolol in forearm vasculature of subjects with essential hypertension Fire simulation and cardiovascular health in firefighters Vascular damage in testicular cancer patients: a study on endothelial activation by bleomycin and cisplatin in vitro Antiangiointravascular ultrasound imaging for coronary thrombosis after cisplatin-based chemotherapy Caspases and calpain are independent mediators of cisplatin-induced endothelial cell necrosis Arterial events in cancer patients-the case of acute coronary thrombosis Vascular toxic effects of cancer therapies Treatmentrelated cardiovascular toxicity in long-term survivors of testicular cancer Comprehensive characterisation of the vascular effects of cisplatin-based chemotherapy in patients with testicular cancer Impact of platinum-based chemotherapy on the progression of atherosclerosis Vascular fingerprint and vascular damage markers associated with vascular events in testicular cancer patients during and after chemotherapy Cardiovascular risk in long-term survivors of testicular cancer Long-term platinum retention after platinumbased chemotherapy in testicular cancer survivors: a 20-year follow-up study Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually Reduced mortality after allogeneic hematopoietic-cell transplantation Late mortality after allogeneic hematopoietic cell transplantation and functional status of long-term survivors: report from the Bone Marrow Transplant Survivor Study Vascular endothelium as 'novel' target of graft-versus-host disease Pericarditis in patients with chronic graft-vs-host disease National Institutes of Health hematopoietic cell transplantation late effects initiative: The Cardiovascular Disease and Associated Risk Factors Working Group Report Prevalence of outpatient cancer treatment in the United States: estimates from the Medical Panel Expenditures Survey (MPES) Chemotherapy-induced cardiotoxicity: detection, prevention, and management Long-term chemotherapy-related cardiovascular morbidity Cardiovascular disease in adult survivors of childhood cancer Epirubicin versus doxorubicin: which is the anthracycline of choice for the treatment of breast cancer? Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin Redox cycling of anthracyclines by cardiac mitochondria. However, elevations in TnI have also been observed in cancer patients receiving cancer therapy, including ICIs without any cardiotoxicities (23, 24) , thus suggesting that its utility may also be limited for the detection of iRC. keywords: age; anthracycline; cancer; cardiac; cardiotoxicity; cardiovascular; ccs; cell; checkpoint; chemotherapy; coronary; data; disease; doxorubicin; endothelial; events; factors; failure; heart; ibrutinib; immune; myocarditis; patients; risk; study; survivors; table; term; therapy; treatment; years cache: cord-282783-ps5jyjkl.txt plain text: cord-282783-ps5jyjkl.txt item: #268 of 449 id: cord-283340-ksyd5l56 author: Choi, Geun Joo title: The Potential Role of Dyslipidemia in COVID-19 Severity: an Umbrella Review of Systematic Reviews date: 2020-09-21 words: 4955 flesch: 36 summary: A meta-analysis Association of hypertension with the severity and fatality of SARS-CoV-2 infection: a meta-analysis Declined serum high density lipoprotein cholesterol is associated with the severity of COVID-19 infection Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series Methodology in conducting a systematic review of systematic reviews of healthcare interventions Using existing systematic reviews in complex systematic reviews AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both Reaching for the stars -rating the quality of systematic reviews with the Assessment of Multiple Systematic Reviews (AMSTAR) 2 AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression Meta-analysis investigating the relationship between clinical features, outcomes, and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia In conclusion, we conducted an umbrella review to identify the findings and contents of systematic reviews and/or meta-analyses of the relationship between dyslipidemia and COVID-19 infection severity. keywords: covid-19; dyslipidemia; meta; quality; review; severity; studies; study cache: cord-283340-ksyd5l56.txt plain text: cord-283340-ksyd5l56.txt item: #269 of 449 id: cord-284332-p4c1fneh author: Bosma, Karen J. title: Pharmacotherapy for Prevention and Treatment of Acute Respiratory Distress Syndrome: Current and Experimental Approaches date: 2012-09-19 words: 14538 flesch: 29 summary: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a metaanalysis of outcome data Efficacy of an expanded ventilator bundle for the reduction of ventilatorassociated pneumonia in the medical intensive care unit Continuous aspiration of subglottic secretions in the prevention of ventilatorassociated pneumonia in the postoperative period of major heart surgery Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial Thromboprophylaxis in medicalsurgical critically ill patients Stress ulcer prophylaxis in critically ill patients: resolving discordant meta-analyses Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial Effects of physical training on functional status in patients with prolonged mechanical ventilation Recent trends in acute lung injury mortality: 1996-2005 Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis Effect of prone positioning in patients with acute respiratory distress syndrome: a metaanalysis Effect of mechanical ventilation in the prone position on clinical outcomes in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis1 Hemodynamic and gas exchange response to inhaled nitric oxide and prone positioning in acute respiratory distress syndrome patients High-frequency oscillatory ventilation in adults: the Toronto experience High-frequency oscillatory ventilation for adult patients with ARDS Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial Extracorporeal membrane oxygenation for 2009 influenza A (H1N1) acute respiratory distress syndrome Ketoconazole prevents acute respiratory failure in critically ill surgical patients A double-blind, prospective, randomized trial of ketoconazole, a thromboxane synthetase inhibitor, in the prophylaxis of the adult respiratory distress syndrome Development, implementation, and evaluation of a ketoconazole practice guideline for ARDS prophylaxis Angiotensin-converting enzyme inhibitor captopril prevents oleic acid-induced severe acute lung injury in rats Rosiglitazone attenuates the severity of sodium taurocholate-induced acute pancreatitis and pancreatitis-associated lung injury Chemically modified tetracycline prevents the development of septic shock and acute respiratory distress syndrome in a clinically applicable porcine model Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: meta-analysis Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: phase IIb, multicenter, randomized, placebo-controlled, clinical trial Ketoconazole for early treatment of acute lung injury and acute respiratory distress syndrome: a randomized controlled trial The Beta-Agonist Lung Injury Trial (BALTI): a randomized placebo-controlled clinical trial Randomized, placebo-controlled trial of an aerosolized beta-2 adrenergic agonist (albuterol) for the treatment of acute lung injury Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome: Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group Bovine surfactant therapy for patients with acute respiratory distress syndrome Venticute in patients with pneumonia or aspiration of gastric contents and intubation/ventilation/oxygenation impairment (BY2001/M1-007) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome Emerging therapies for treatment of acute lung injury and acute respiratory distress syndrome The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury Arachidonic acid remodeling in human inflammatory cells migrating to the lung in vivo Recent advances in genetic predisposition to clinical acute lung injury Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock Pharmacotherapy of acute lung injury and acute respiratory distress syndrome Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome Does programmed cell death (apoptosis) play a role in the development of multiple organ dysfunction in critically ill patients? keywords: acute; ali; alveolar; ards; day; distress; group; injury; lung; mortality; neutrophil; patients; phase; results; risk; studies; study; surfactant; syndrome; treatment; trial; ventilation cache: cord-284332-p4c1fneh.txt plain text: cord-284332-p4c1fneh.txt item: #270 of 449 id: cord-284880-xsh3wkqy author: Bandaly, Victor title: The Fate of Mengovirus on Fiberglass Filter of Air Handling Units date: 2017-06-28 words: 4712 flesch: 53 summary: Air filters consist of clusters of fibers (mats, felts, papers, glass). They pointed out differences in inactivation between enveloped and nonenveloped respiratory viruses. keywords: air; filter; infectivity; mengovirus; min; study; virus; viruses cache: cord-284880-xsh3wkqy.txt plain text: cord-284880-xsh3wkqy.txt item: #271 of 449 id: cord-285244-2suwmika author: Blau, Ina title: Violation of digital and analog academic integrity through the eyes of faculty members and students: Do institutional role and technology change ethical perspectives? date: 2020-07-22 words: 11046 flesch: 33 summary: Doctoral dissertation, Arizona State University Investigating the probability of student cheating: The relevance of student characteristics, assessment items, perceptions of prevalence and history of engagement Croatian medical students see academic dishonesty as an acceptable behaviour: A cross-sectional multicampus study Student cheating and plagiarism in the Internet era: A wake-up call NESB and ESB students' attitudes and perceptions of plagiarism The dishonesty of honest people: A theory of self-concept maintenance Motivational perspectives on student cheating: Toward an integrated model of academic dishonesty Custom essay writers, freelancers, and other paid third parties Technology as a double edged sword: A promise yet to be fulfilled or a vehicle for cheating Cheating and electronic plagiarism-Scope, consequences and detection Students' perceptions of cheating and plagiarism in higher institutions Applying the power of association on campus: A model code of academic integrity Institutional policies and faculty perceptions of student academic dishonesty. An exploration of the motivators of student academic dishonesty in higher education Managing academic dishonesty in Australian universities: Implications for teaching, learning and scholarship. keywords: analog; cheating; digital; facilitation; faculty; members; penalties; plagiarism; severity; students; study; vai cache: cord-285244-2suwmika.txt plain text: cord-285244-2suwmika.txt item: #272 of 449 id: cord-285898-rtqkvf63 author: Padberg, Stephanie title: Anti-infective Agents date: 2014-09-29 words: 24011 flesch: 39 summary: Results of a population-based Hungarian case-control study A case-control teratological study of spiramycin, roxithromycin, oleandomycin and josamycin A teratological study of lincosamides A population-based case-control teratologic study of oral oxytetracycline treatment during pregnancy A teratological study of aminoglycoside antibiotic treatment during pregnancy A population-based case-control teratologic study of oral chloramphenicol treatment during pregnancy Augmentin treatment during pregnancy and the prevalence of congenital abnormalities: a population-based case-control teratologic study Use of cephalosporins during pregnancy and in the presence of congenital abnormalities: a population-based, case-control study The teratogenic risk of trimethoprim-sulfonamides: a population based case-control study Nitrofurantoin and congenital abnormalities A population-based case-control study of the safety of oral anti-tuberculosis drug treatment during pregnancy A population-based case-control teratological study of vaginal econazole treatment during pregnancy A population-based case-control teratological study of oral nystatin treatment during pregnancy A case-control teratological study of vaginal natamycin treatment during pregnancy Preterm birth reduction after clotrimazole treatment during pregnancy Population-based case-control teratologic study of topical miconazole A population-based case-control study of oral griseofulvin treatment during pregnancy Tolnaftate spray treatment during pregnancy Effect of mebendazole therapy during pregnancy on birth outcome Periconceptional exposure to efavirenz and neural tube defects First-trimester itraconazole exposure and pregnancy outcome: a prospective cohort study of women contacting teratology information services in Italy Use of amphotericin B during pregnancy: case report and review The safety of the combination artesunate and pyrimethamine-sulfadoxine given during pregnancy Birth outcome of 1886 pregnancies after exposure to phenoxymethylpenicillin in utero The effects of telbivudine in late pregnancy to prevent intrauterine transmission of the hepatitis B virus: a systematic review and meta-analysis Pregnancy outcome after gestational exposure to mebendazole: a prospective controlled cohort study Pregnancy outcome after gestational exposure to metronidazole: a prospective controlled cohort study Genotoxicity and carcinogenicity of metronidazole Association between maternal fever and psychological/behavior outcomes: a hypothesis Safety of oseltamivir in pregnancy: a review of preclinical and clinical data Postmarketing surveillance of medications and pregnancy outcomes: clarithromycin and birth malformations Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents Increased risk of severe infant anemia after exposure to maternal HAART Pregnancy outcome following maternal use of zanamivir or oseltamivir during the 2009 influenza A/H1N1 pandemic: a national prospective surveillance study Europeans Guidelines for treatment of HIVinfected adults in Europe Hyperthermia and birth defects A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes A prospective controlled multicentre study of clarithromycin in pregnancy Effect of quinine therapy on plasma glucose and plasma insulin levels in pregnant women infected with Plasmodium falciparum malaria in Gezira state Cryptococcal pneumonia complicating pregnancy Exposure to antiretroviral therapy in utero or early life: the health of uninfected children born to HIV-infected women Fosfomycin versus other antibiotics for the treatment of cystitis: a meta-analysis of randomized controlled trials Hematologic effects of maternal antiretroviral therapy and transmission prophylaxis in HIV-1-exposed uninfected newborn infants Birth defects in a national cohort of pregnant women with HIV infection in Italy Pharmacokinetics and safety of single-dose tenofovir disoproxil fumarate and emtricitabine in HIV-1-infected pregnant women and their infants Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohorts Myelomeningocele in a child with intrauterine exposure to efavirenz Successful use of darunavir, etravirine, enfuvirtide and tenofovir/emtricitabine in pregnant woman with multiclass HIV resistance Maternal exposure to prescription and non-prescription pharmaceuticals or drugs of abuse and risk of craniosynostosis Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial Placental transfer and pharmacokinetics of lopinavir and other protease inhibitors in combination with nevirapine at delivery Acyclovir pregnancy registry and valacyclovir pregnancy registry: Interim report for 1 Exposure to nitrofurantoin during the first trimester of pregnancy and the risk for major malformations Quinolone arthropathy -acute toxicity to immature articular cartilage Edwards: discoverer of maternal hyperthermia as a human teratogen Pharmacokinetics of sulfadoxinepyrimethamine in HIV-infected and uninfected pregnant women in Western Kenya Pharmacokinetics of oseltamivir according to trimester of pregnancy Maternal and neonatal outcomes after antepartum treatment of influenza with antiviral medications Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis Lack of risk of adverse birth outcomes after deworming in pregnant women A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection Lack of tumors in infants with perinatal HIV-1 exposure and fetal/neonatal exposure to zidovudine Review of beta-lactam antibiotics in pregnancy. ORACLE Collaborative Group Antifungal therapy during pregnancy Is gentamicin ototoxic to the fetus? Short-acting sulfonamides near term and neonatal jaundice Failure of metronidazole to prevent preterm delivery among pregnant women with asymptomatic Trichomonas vaginalis infection Prevalence of congenital anomalies in infants with in utero exposure to antiretrovirals No association between griseofulvin and conjoined twinning Drug rash with eosinophilia and systemic symptoms syndrome and renal toxicity with a nevirapine-containing regimen in a pregnant patient with human immunodeficiency virus Investigation of metronidazole use during pregnancy and adverse birth outcomes Use of antiretroviral therapy in pregnant HIVinfected women and the risk of premature delivery: a meta-analysis Transplacental passage of vancomycin in noninfected term pregnant women Serum erythromycin levels in pregnancy Birth outcome following maternal use of fluoroquinolones Perinatal antiretroviral treatment and hematopoiesis in HIV-uninfected infants Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria Multidrug-resistant tuberculosis in pregnancy: case report and review of the literature Drug hepatotoxicity in pregnancy Increased risk of low birthweight and small for gestational age infants among women with tuberculosis Maternal exposure to amoxicillin and the risk of oral clefts Safety of macrolides during pregnancy Association of high-dose bifonazole administration during early pregnancy and severe limb reduction defects in the newborn Safety of telbivudine treatment for chronic hepatitis B for the entire pregnancy Pregnancy outcome following gestational exposure to fluoroquinolones: a multicenter prospective controlled study Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype Erythromycin use during pregnancy in relation to pyloric stenosis Congenital defects among children born to women under supervision or treatment for pulmonary tuberculosis Successful use of dapsone in refractory pregnancy-associated idiopathic thrombocytopenic purpura Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis First trimester use of macrolides and risk of major malformations {OTIS Abstract} Case report: nucleoside analogue-induced lactic acidosis in the third trimester of pregnancy Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1 Assessment of infant development during an 18-month follow-up after treatment of infections in pregnant women with cefuroxime axetil Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia Safety and efficacy of fosamprenavir in human immunodeficiency virus-infected pregnant women Transplacental passage of protease inhibitors at delivery Prospective assessment of pregnancy outcomes after first-trimester exposure to fluconazole A systematic review of the impact of malaria prevention in pregnancy on low birth weight and maternal anemia Hepatotoxicity of erythromycin estolate during pregnancy Preliminary data on exposure to mebendazole during pregnancy {Abstract} A randomized comparison of artesunate-atovaquoneproguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy Randomized comparison of mefloquine-artesunate versus quinine in the treatment of multidrug-resistant falciparum malaria in pregnancy Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria A randomised controlled trial of artemetherlumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy The effects of quinine and chloroquine antimalarial treatments in the first trimester of pregnancy High neonatal concentrations of raltegravir following transplacental transfer in HIV-1 positive pregnant women Treatment of vulvovaginal candidiasis in pregnancy. keywords: animal; birth; case; combination; data; defects; e.g.; effects; evidence; exposure; fetus; hiv; infections; malaria; malformations; population; pregnancy; pregnancy registry; recommendation; registry; risk; safety; second; studies; study; teratogenic; therapy; treatment; trimester; trimester exposure; use; women cache: cord-285898-rtqkvf63.txt plain text: cord-285898-rtqkvf63.txt item: #273 of 449 id: cord-286075-yp2ta24o author: Nacul, Luis title: How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS date: 2020-08-11 words: 8475 flesch: 19 summary: An operational definition Postviral Fatigue Syndrome-The Saga of Royal Free Disease Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort Chronic fatigue: risk factors for symptom persistence in a 2 1/2-year follow-up study Chronic fatigue in primary care: prevalence, patient characteristics, and outcome The prognosis of chronic fatigue and chronic fatigue syndrome: a systematic review Regional distribution of fatiguing illnesses in the United States: a pilot study Sub-typing CFS patients on the basis of 'minor' symptoms Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics Symptom patterns in long-duration chronic fatigue syndrome Onset patterns and course of myalgic encephalomyelitis/chronic fatigue syndrome. Fatigue Biomed Health Behav Environmental exposures as a potential underlying factor in chronic fatigue syndrome; a case report Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells from individuals with chronic fatigue syndrome Recent insights into 3 underrecognized conditions: myalgic encephalomyelitis-chronic fatigue syndrome, fibromyalgia, and environmental sensitivities-multiple chemical sensitivity Inability of myalgic encephalomyelitis/chronic fatigue syndrome patients to reproduce VO2peak indicates functional impairment Genetic And Environmental Factors Impact Chronic Fatigue Syndrome Patients Biomarkers for chronic fatigue keywords: abnormalities; cfs; chronic; disease; dysfunction; encephalomyelitis; fatigue; fatigue syndrome; mechanisms; myalgic; patients; research; studies; study; symptoms; syndrome; system cache: cord-286075-yp2ta24o.txt plain text: cord-286075-yp2ta24o.txt item: #274 of 449 id: cord-286237-x6dr6rsh author: Maes, Bastiaan title: Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial date: 2020-06-03 words: 11261 flesch: 42 summary: Ethical and legal aspects The study will be conducted cfr the latest version of the ICH E6 (R2) GCP guidelines, creating a standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical studies that provides assurance that the data and reported results are accurate and that the rights, integrity and confidentiality of study subjects are protected. Monitoring services will consist of the following (non-exhaustive list): -review of informed consents and the followed process -check on recruitment status -checking for protocol deviations/violations -checking GCP compatibility -check on safety reporting compliance -IMP handling and storage -review of study data … This study can be inspected at any time by regulatory agencies during or after completion of the study. keywords: anakinra; blood; care; covid-19; cytokine; data; days; hospital; il-1; il-6; improvement; injection; investigator; patients; siltuximab; study; subject; time; tocilizumab; treatment; trial; use cache: cord-286237-x6dr6rsh.txt plain text: cord-286237-x6dr6rsh.txt item: #275 of 449 id: cord-286411-7sgr29xx author: Zhou, Zibanai title: Critical shifts in the global tourism industry: perspectives from Africa date: 2020-10-06 words: 12279 flesch: 36 summary: The fact that the BRICS, ageing population, terrorism and trophy hunting issues are taking root in the marketplace it is about time that emerging tourist destinations tourism starts a serious conversation to establish the implications of these dynamics on the tourism system. Key interview informants were qualified as tourism experts on the basis of their extensive working experience directly in various sub-sectors of the tourism industry at regional and international level, that is, hotels, tour operations, conventions, NTO as regional and international tourism markets, tourism attachés in charge of overseas tourism markets, tourism market development, planning and forecasting. keywords: africa; brics; countries; destinations; development; dynamics; economic; future; global; growth; hunting; international; market; population; research; study; terrorism; tourism; tourism development; tourism industry; tourism market; tourism sector; travel; trophy; world cache: cord-286411-7sgr29xx.txt plain text: cord-286411-7sgr29xx.txt item: #276 of 449 id: cord-286527-e795m6tk author: Sheskin, Mark title: Online Developmental Science to Foster Innovation, Access, and Impact date: 2020-07-02 words: 2364 flesch: 30 summary: Participating in developmental studies is an accessible way for families to interact with scientists and to learn about scientific research. In addition to making study development easier, standard methods decrease cognitive load for repeat participants (e.g., by already being familiar with instructions and what is expected of them), leading to a better experience for the family and cleaner data for the study. keywords: cradle; data; researchers; science; studies; study cache: cord-286527-e795m6tk.txt plain text: cord-286527-e795m6tk.txt item: #277 of 449 id: cord-286565-bmcsyfz9 author: Akdeniz, Gulsum title: A Survey of Attitudes, Anxiety Status, and Protective Behaviors of the University Students During the COVID-19 Outbreak in Turkey date: 2020-07-15 words: 4223 flesch: 44 summary: A Study on Immediate Mental Health Status and Psychoneuroimmunity Prevention Measures of Chinese Workforce The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety Anxiety sensitivity and emotion regulation as mechanisms of successful CBT outcome for anxietyrelated disorders in a naturalistic treatment setting A Longitudinal Study on the Mental Health of General Population during the COVID-19 Epidemic in China Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Learning to use statistical tests in psychology The use of psychological testing for treatment planning and outcomes assessment: General considerations The 2014 Ebola Outbreak and Mental Health: Current Status and Recommended Response An inventory for measuring clinical anxiety: Psychometric properties Turkish version of the Beck Anxiety Inventory: Psychometric properties Using Multivariate Statistics Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Google searches for the keywords of wash hands predict the speed of national spread of COVID-19 outbreak among 21 countries Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: A scoping review Social reaction toward the 2019 novel coronavirus (COVID-19) The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital Fear and stigma: the epidemic within the SARS outbreak An outbreak of fear rumours and stigma: Psychosocial support for the Ebola virus disease outbreak in West Africa The Fear of COVID-19 Scale: Development and Initial Validation Television viewing, computer game playing, and Internet use and self-reported time to bed and time out of bed in secondary-school children Internet overuse and excessive daytime sleepiness in adolescents Mobile phone use and stress, sleep disturbances, and symptoms of depression among young adults-a prospective cohort study Sleepy teens: social media use in adolescence is associated with poor sleep quality, anxiety, depression, and low self-esteem The association between social media use and sleep disturbance among young adults A four-wave, cross-lagged model of problematic internet use and mental health among Chinese college students: Disaggregation of within-person and between-person effects Reducing Nursing Student Anxiety in the Clinical Setting: An Integrative Review Type 1 interferons as a potential treatment against COVID-19 TreaTment for emerging viruses: Convalescent plasma and COVID-19 The SARS-CoV-2 vaccine pipeline: an overview Early Assessment of Anxiety and Behavioral Response to Novel Swine-Origin Influenza A(H1N1) Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients Gender Differences in Patients With COVID-19: Focus on Severity and Mortality Characterize health and economic vulnerabilities of workers to control the emergence of COVID-19 in an industrial zone in Vietnam Mental Health Strategies to Combat the Psychological Impact of COVID-19 Beyond Paranoia and Panic As a matter of fact, a study by Filder Smith and Do Freedman also stated that social distances would reduce transmission, as such outbreak diseases require a certain intimacy of people (15) . keywords: anxiety; coronavirus; covid-19; disease; health; outbreak; respondents; status; study cache: cord-286565-bmcsyfz9.txt plain text: cord-286565-bmcsyfz9.txt item: #278 of 449 id: cord-286889-l765mxmy author: Stangeland, Paula A. title: Disaster Nursing: A Retrospective Review date: 2010-12-31 words: 7369 flesch: 46 summary: 17, 18 Despite that the ANA acknowledges that working during disasters places nurses in unusual situations and conditions, the organization's code of ethics defines and directs the responsibilities of all practicing nurses regardless of the situation or setting. Research has shown that nursing schools may be lacking in the area of preparing students for disaster nursing. keywords: care; colleagues; disaster; emergency; health; nurses; nursing; participants; preparedness; report; researchers; stress; study; work cache: cord-286889-l765mxmy.txt plain text: cord-286889-l765mxmy.txt item: #279 of 449 id: cord-286932-2gjnpqqa author: Lee, Yung title: Impact of hospital lockdown secondary to COVID-19 and past pandemics on surgical practice: A living rapid systematic review date: 2020-11-12 words: 2958 flesch: 39 summary: 13 Studies reporting outcomes of patients undergoing surgery during an epidemic-caused hospital lockdown and studies investigating the impact of lockdown on surgical HCW and surgical practice were included. Studies conducted during COVID-19 accounted for 98.6% of the included patients, while 1.2% were from studies during SARS, and 0.15% were from studies during MERS. keywords: care; covid-19; epidemics; hcw; measures; studies cache: cord-286932-2gjnpqqa.txt plain text: cord-286932-2gjnpqqa.txt item: #280 of 449 id: cord-287367-1sdt9zz8 author: Andrews, Denise title: Multiplex PCR point of care testing versus routine, laboratory-based testing in the treatment of adults with respiratory tract infections: a quasi-randomised study assessing impact on length of stay and antimicrobial use date: 2017-10-10 words: 6431 flesch: 45 summary: 20% of control arm patients and 24% of intervention arm patients had an RP detected. FilmArray® POC testing occurred on even days of the month (intervention) or routine, laboratory-based RP PCR testing +/− atypical serology on odd days (control). keywords: arm; control; filmarray; intervention; patients; poc; respiratory; results; stay; study; testing; time cache: cord-287367-1sdt9zz8.txt plain text: cord-287367-1sdt9zz8.txt item: #281 of 449 id: cord-287607-d3k26aar author: Emamaullee, Juliet title: Rapid Adaptation of a Surgical Research Unit to Conduct Clinical Trials during the Coronavirus-19 Pandemic. date: 2020-06-29 words: 3273 flesch: 30 summary: Ongoing ‘Stay at Home’ orders and institutional policies mandating ‘Work from Home’ for non-essential employees, which includes most research personnel, have impacted the ability to implement and conduct clinical studies. By centralizing the clinical trials process within the department and under the guidance of an experienced Chief and seasoned research team, the capacity for clinical studies has increased substantially while maintaining a stable number of study personnel (Figure 1) . keywords: covid-19; enrollment; research; studies; study; team; trials cache: cord-287607-d3k26aar.txt plain text: cord-287607-d3k26aar.txt item: #282 of 449 id: cord-287742-y1j9x5ne author: Lee, Kai Wei title: Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis date: 2020-10-06 words: 6552 flesch: 38 summary: Ischemic stroke was the predominant stroke, and it was observed in 90.3% of stroke cases as compared to 9.7% patients presenting with hemorrhagic stroke. The following data were extracted from every study: the last name of the first author, year of publication, country, severity status, study design, patient characteristics (ethnicity composition, gender, and mean age), comorbidities (diabetes, hyperlipidemia, hypertension, ischemic heart disease, heart failure, previous stroke, chronic kidney disease/end-stage renal disease, number of stroke patients per overall participants, any information relevant to strokes such as the location of stroke [arterial or venous]), types of stroke (ischemic or haemorrhagic), classification of stroke, mortality rate, and blood parameters. keywords: analysis; coronavirus; covid-19; data; disease; infection; ischemic; meta; patients; review; risk; stroke; studies cache: cord-287742-y1j9x5ne.txt plain text: cord-287742-y1j9x5ne.txt item: #283 of 449 id: cord-287957-diyz54qy author: Deriba, Berhanu Senbeta title: Patient Satisfaction and Associated Factors During COVID-19 Pandemic in North Shoa Health Care Facilities date: 2020-10-13 words: 4257 flesch: 40 summary: Overall, 44.6% of patients with chronic disease were satisfied with the service they received from health facilities. Therefore, this study aimed to assess patient satisfaction and associated factors during the COVID-19 pandemic among chronic patients who had follow-up at public health facilities in the North Shoa Zone, Oromia region, Ethiopia. keywords: covid-19; data; disease; facilities; health; healthcare; hospital; participants; patient; satisfaction; study cache: cord-287957-diyz54qy.txt plain text: cord-287957-diyz54qy.txt item: #284 of 449 id: cord-287958-tcn2hlmo author: Bhattacharya, Subhasis title: The behaviour of Infection, Survival and Testing Effort Variables of SARS-CoV-2: A Theoretical Modelling based on Optimization Technique date: 2020-11-11 words: 3604 flesch: 49 summary: With the initiation of human intervention, the natural gross biological growth of infected population is to be affected and the net rate of growth of infected population can be expressed as the difference between gross biological growth of infected population and identification function of the asymptomatic carriers. From such analysis study found that as per our assumption but we get . keywords: effort; function; identification; infected; infection; study cache: cord-287958-tcn2hlmo.txt plain text: cord-287958-tcn2hlmo.txt item: #285 of 449 id: cord-288052-qfjet2sa author: Paparini, Sara title: Case study research for better evaluations of complex interventions: rationale and challenges date: 2020-11-10 words: 3889 flesch: 30 summary: key: cord-288052-qfjet2sa authors: Paparini, Sara; Green, Judith; Papoutsi, Chrysanthi; Murdoch, Jamie; Petticrew, Mark; Greenhalgh, Trish; Hanckel, Benjamin; Shaw, Sara title: Case study research for better evaluations of complex interventions: rationale and challenges date: 2020-11-10 journal: BMC Med DOI: 10.1186/s12916-020-01777-6 sha: doc_id: 288052 cord_uid: qfjet2sa BACKGROUND: The need for better methods for evaluation in health research has been widely recognised. We argue that case study research—currently denigrated as poor evidence—is an under-utilised resource for not only providing evidence about context and transferability, but also for helping strengthen causal inferences when pathways between intervention and effects are likely to be non-linear. keywords: case; context; evidence; health; interventions; research; studies; study cache: cord-288052-qfjet2sa.txt plain text: cord-288052-qfjet2sa.txt item: #286 of 449 id: cord-288487-hs3wfffs author: Lambert, Stephen B title: The cost of community-managed viral respiratory illnesses in a cohort of healthy preschool-aged children date: 2008-01-24 words: 5666 flesch: 39 summary: We calculated mean costs (total and by categories) with 95% confidence intervals (95% CI) and median costs with interquartile ranges for ARIs in study children. Influenza illnesses had a mean cost of $904, compared with RSV, $304, the next most expensive single-virus illness, although confidence intervals overlapped. keywords: aris; children; cost; data; illnesses; impact; influenza; mean; study; time; virus; viruses cache: cord-288487-hs3wfffs.txt plain text: cord-288487-hs3wfffs.txt item: #287 of 449 id: cord-289305-mfjyjjer author: Lee, Min Hye title: A systematic review on the causes of the transmission and control measures of outbreaks in long-term care facilities: Back to basics of infection control date: 2020-03-10 words: 7552 flesch: 46 summary: Three of them were long-lasting outbreaks with multiple clusters for more than 6 months, which suggested that an accurate identification of how pathogens spread was a fundamental step in outbreak control. Forming a local support network between acute hospitals and LTCFs at a regional level would be a potential way to close the gaps and to enhance outbreak control practices in LTCFs without adequate capacity [74] . keywords: care; control; hand; hygiene; infection; influenza; ltcfs; measures; outbreaks; review; studies; study; transmission cache: cord-289305-mfjyjjer.txt plain text: cord-289305-mfjyjjer.txt item: #288 of 449 id: cord-290347-q6r6g7ue author: Williams, Lloyd B. title: Impact and Trends in Global Ophthalmology date: 2020-06-22 words: 5150 flesch: 39 summary: OneHealth Tool will be adding eye care to its healthcare planning interventions in 2020 and we look forward to seeing its effectiveness in assisting eye care planning particularly in the setting of detecting and intervening early in cataract blindness. There is expected to be an increasing demand for global eye care due to an aging population, changing lifestyles (leading to increased lifestyle-related blindness (e.g., diabetes)), and population growth. keywords: blindness; care; countries; eye; global; impairment; retinopathy; screening; study; trachoma; vision cache: cord-290347-q6r6g7ue.txt plain text: cord-290347-q6r6g7ue.txt item: #289 of 449 id: cord-291083-nd7cew7v author: Vargas-Medrano, Javier title: Psychological and Neurobiological Aspects of Suicide in Adolescents: Current Outlooks date: 2020-08-05 words: 7751 flesch: 34 summary: Research has found substantial gender and racial/ethnic differences in suicide risk factors among youth underscoring the need for this (Lee and Wong, 2020) . Hopelessness is considered as one of the risk factors for suicidality; however, it is also known to be associated with major depression; therefore hopelessness can be a contradictory factor when determining suicide risk by itself (Efstathiou et al., 2018; Wolfe et al., 2019; Young et al., 1996) . keywords: adolescents; attempts; behavior; brain; childhood; cortex; depression; et al; factors; ideation; risk; self; studies; study; suicidal; suicidality; suicide cache: cord-291083-nd7cew7v.txt plain text: cord-291083-nd7cew7v.txt item: #290 of 449 id: cord-291271-movbn4dn author: Jahangiry, Leila title: Risk perception related to COVID-19 among the Iranian general population: an application of the extended parallel process model date: 2020-10-19 words: 3338 flesch: 49 summary: Perceived risk scores showed that participants with confirmed coronavirus cases had significantly higher scores except for the perceived susceptibility scores. This indicated that more than half of participants had high perceived efficacy (i.e., self-efficacy and response efficacy). keywords: control; covid-19; efficacy; participants; risk; study cache: cord-291271-movbn4dn.txt plain text: cord-291271-movbn4dn.txt item: #291 of 449 id: cord-291540-raksomda author: None title: July 2020 New in Review date: 2020-07-31 words: 3301 flesch: 38 summary: Are obstructive sleep apnea and sleep improved in response to multidisciplinary weight loss interventions in youth with obesity? The investigators hypothesized that multidisciplinary weight loss interventions will effectively reduce obstructive sleep apnea (OSA) indicators such as the apnea-hypopnea index, oxygen desaturation index, and obstructive apnea-hypopnea index, and in improving sleep duration and sleep architecture. keywords: analysis; authors; food; health; intervention; meta; participants; review; risk; sample; studies; weight cache: cord-291540-raksomda.txt plain text: cord-291540-raksomda.txt item: #292 of 449 id: cord-291851-xesef17i author: Wong, Yu-Jun title: A systematic review and meta-analysis of the COVID-19 associated liver injury date: 2020-08-31 words: 4386 flesch: 47 summary: The objective of this meta-analysis is to compare the risk and clinical outcome of COVID-19 associated liver injury between COVID-19 patients with severe and non-severe COVID-19. COVID-19 associated liver injury is defined as any liver damage in patients COVID-19 patients, with or without the pre-existing liver disease [5] . keywords: analysis; covid-19; disease; injury; liver; patients; studies cache: cord-291851-xesef17i.txt plain text: cord-291851-xesef17i.txt item: #293 of 449 id: cord-292209-d1ty9etr author: Horta, Bernardo L title: Prevalence of antibodies against SARS-CoV-2 according to socioeconomic and ethnic status in a nationwide Brazilian survey date: 2020-10-29 words: 4333 flesch: 46 summary: O ajuste regional reduziu as taxas de prevalência de acordo com a riqueza, educação e etnia, mas os resultados permaneceram estatisticamente significativos. Se utilizó el análisis de los componentes principales de los bienes para clasificar la posición socioeconómica en cinco quintiles de riqueza. keywords: analyses; antibodies; brazil; cov-2; covid-19; individuals; prevalence; region; results; sars; study; subjects; test cache: cord-292209-d1ty9etr.txt plain text: cord-292209-d1ty9etr.txt item: #294 of 449 id: cord-292544-m7jyydf1 author: Grau-Pujol, Berta title: Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol for a multicentre, double-blind randomized controlled trial date: 2020-07-29 words: 4577 flesch: 44 summary: Study participant flowchart The occurrence of an AE or SAE may come to the attention of study personnel during study visits and interviews of a study participant presenting for medical care, or upon review by the study monitor. keywords: cov-2; covid-19; group; healthcare; hydroxychloroquine; prep; sars; study; workers cache: cord-292544-m7jyydf1.txt plain text: cord-292544-m7jyydf1.txt item: #295 of 449 id: cord-292559-b21j9sf3 author: Karcher, Nicole R. title: The ABCD study: understanding the development of risk for mental and physical health outcomes date: 2020-06-15 words: 10090 flesch: 34 summary: In addition, we will discuss the challenges and opportunities to understanding both healthy development and the emergence of risk from ABCD Study data. Emerging research examining resting state functional connectivity (RSFC) to delineate the functional architecture of the brain found RSFC networks were highly reproducible across two samples of ABCD Study data, shared many features of adult-level networks, and showed associations with cognitive functioning [42] . keywords: abcd; abcd study; brain; childhood; data; development; factors; health; measures; psychopathology; research; risk; sample; studies; study; substance; use; youth cache: cord-292559-b21j9sf3.txt plain text: cord-292559-b21j9sf3.txt item: #296 of 449 id: cord-292853-xihpfidg author: Ford, Julian D. title: Social, cultural, and other diversity issues in the traumatic stress field date: 2015-08-07 words: 18827 flesch: 28 summary: Such an approach is consistent with new theoretical views of refugee traumatic stress, which include the concepts of cultural bereavement, cultural trauma, family consequences of refugee trauma, community trauma, and social suffering (Weine, 2008) . Because not all psychologists have expertise in assessing traumatic stress risk and/or social psychological (Continued ) factors, the assessment should be conducted by psychologists who have this specific expertise. keywords: abuse; american; children; community; cross; disaster; disorder; exposure; family; girls; groups; health; people; persons; psychological; psychologists; ptsd; refugees; risk; services; stress; stressors; study; symptoms; torture; trauma; treatment; united; violence; women cache: cord-292853-xihpfidg.txt plain text: cord-292853-xihpfidg.txt item: #297 of 449 id: cord-292978-qfw1uqvp author: Thakrar, Amit title: Thirty-Day Mortality Rate of Patients With Hip Fractures During the COVID-19 Pandemic: A Single Centre Prospective Study in the United Kingdom date: 2020-07-08 words: 3420 flesch: 51 summary: key: cord-292978-qfw1uqvp authors: Thakrar, Amit; Chui, Karen; Kapoor, Akhil; Hambidge, John title: Thirty-Day Mortality Rate of Patients With Hip Fractures During the COVID-19 Pandemic: A Single Centre Prospective Study in the United Kingdom date: 2020-07-08 journal: J Orthop Trauma DOI: 10.1097/bot.0000000000001889 sha: doc_id: 292978 cord_uid: qfw1uqvp During the COVID-19 pandemic, the care of hip fracture patients remains a clinical priority. Our study demonstrated a significant increase in 30-day mortality among hip fracture patients during the first 30 days of the COVID-19 pandemic in the United Kingdom. keywords: covid-19; day; hip; mortality; patients; study cache: cord-292978-qfw1uqvp.txt plain text: cord-292978-qfw1uqvp.txt item: #298 of 449 id: cord-293186-yxpkqbey author: Mamo, Yitagesu title: Perception Toward Quarantine for COVID-19 Among Adult Residents of Selected Towns in Southwest Ethiopia date: 2020-10-30 words: 4597 flesch: 48 summary: Having training on COVID-19 was among a factor positively associated with perception toward quarantine ie, when we change the status of training from nontrained to trained the perception toward quarantine score will be increased by 2.76 units keeping other variables constant (β=2.76, p=0.005). Quantifying the impact of community quarantine on SARS transmission in Ontario: estimation of secondary case count difference and number needed to quarantine Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions The Covid-19 Shock to Developing Countries: Towards a Whatever It Takes Programme for the Two-Thirds of the World's Population Being Left Behind Addressing the Impacts of COVID-19 in Food Crises Office for Africa; Scaling up coronavirus outbreak readiness in Ethiopia notification on Situational COVID 19 Update Covid-19 -the Law and Limits of Quarantine Preventive behaviors, and mental health in Turkey Risk perceptions of COVID-19 around the world World Health Organization (WHO) Factors influencing compliance with quarantine in Toronto during the 2003 SARS outbreak Letter to the Editor Aggregated COVID-19 suicide incidences in India: fear of COVID-19 infection is the prominent COVID-19-Related Suicides in Bangladesh Due to Lockdown and Economic Factors: case Study Evidence from Media Reports Lessons from the history of quarantine, from plague to influenza A Review Author (s): susan Chinn Review by: susan Chinn Source: journal of the Royal Statistical Public perceptions of quarantine: community-based telephone survey following an infectious disease outbreak Practice and Attitude towards Epilepsy and Associated Factors among Adults in Goncha Siso Enesie Woreda Rural Kebeles, East Gojjam Community knowledge and attitudes of epilepsy in rural and urban Mukono district, Uganda; a cross sectional study The impacts of vulnerability, perceived risk, and fear on preventive behaviours against COVID-19 Exploring the Associations Between Resilience, Dispositional Hope, Preventive Behaviours, Subjective Well-Being, and Psychological Health Among Adults During Early Stage of COVID-19 American Journal of Infection Control Middle East respiratory syndrome in South Korea during 2015: risk-related perceptions and quarantine attitudes Risk perception and compliance with quarantine during the SARS outbreak How to improve adherence with quarantine: rapid review of the evidence The authors are very grateful for Mizan-Tepi University, the study participants, data collectors and supervisors. keywords: community; covid-19; data; health; knowledge; perception; quarantine; respondents; score; study cache: cord-293186-yxpkqbey.txt plain text: cord-293186-yxpkqbey.txt item: #299 of 449 id: cord-293522-gg706q8s author: Toumi, Mondher title: Commentary on “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial” by Gautret et al date: 2020-05-13 words: 5239 flesch: 48 summary: The patients who refused to receive hydroxychloroquine were used as control patients, as were noneligible patients. [21] , we could assess the proportion of patients who were negative at 65% for hydroxychloroquine arm compared with 12.5% for the control arm, which is still statistically significant (p = 0.0012) and very clinically relevant. keywords: clinical; control; coronavirus; covid-19; health; hydroxychloroquine; patients; results; study; treatment cache: cord-293522-gg706q8s.txt plain text: cord-293522-gg706q8s.txt item: #300 of 449 id: cord-294005-gjrj1gvr author: Odei Erdiaw-Kwasie, Michael title: Citizen participation dilemmas in water governance: An empirical case of Kumasi, Ghana date: 2020-12-31 words: 8596 flesch: 36 summary: Our customers' interest in taking part in the survey has dwindled significantly and that GWCL has resorted to other mechanisms for engaging citizens in water governance [Manager at North B] It emerged from the study that 25% of the respondents prefer to participate in water governance issues through the telephone. key: cord-294005-gjrj1gvr authors: Odei Erdiaw-Kwasie, Michael; Abunyewah, Matthew; Edusei, Joseph; Buernor Alimo, Emmanuel title: Citizen participation dilemmas in water governance: An empirical case of Kumasi, Ghana date: 2020-12-31 journal: World Development Perspectives DOI: 10.1016/j.wdp.2020.100242 sha: doc_id: 294005 cord_uid: gjrj1gvr Abstract Citizen participation in decision-making on water-related initiatives offers a valuable pathway to move towards a more equitable and sustainable water delivery, now and into the future. keywords: citizen; decision; delivery; ghana; governance; gwcl; issues; making; participation; public; respondents; study; water; water governance cache: cord-294005-gjrj1gvr.txt plain text: cord-294005-gjrj1gvr.txt item: #301 of 449 id: cord-294910-gnc04ax1 author: Nogueira, Paulo Jorge title: The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Cases date: 2020-07-24 words: 4943 flesch: 36 summary: The results of the present study registered potential different pathophysiological mechanisms for COVID-19 mortality, suggesting the need for a team approach between different medical specialties in order to maximize the probabilities of recovery for COVID-19 patients. Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension National age and coresidence patterns shape COVID-19 vulnerability Acute kidney injury is associated with the mortality of coronavirus disease 2019 Determinants of blood pH in health and disease Is the kidney a target of SARS-CoV-2? Kidney disease is associated with in-hospital death of patients with COVID-19 Impact of Cerebrovascular and Cardiovascular Diseases on Mortality and Severity of COVID-19-Systematic Review, Meta-analysis, and Meta-regression Issues of Cardiovascular Risk Management in People With Diabetes in the COVID-19 Era North American COVID-19 ST-segment elevation myocardial infarction (NACMI) registry: Rationale, design, and implications Takotsubo syndrome during SARS-CoV-2 pneumonia: A possible cardiovascular complication Myocardial injury determination improves risk stratification and predicts mortality in COVID-19 patients The Heart in COVID19: Primary Target or Secondary Bystander? COVID 19 and heart failure: From infection to inflammation and angiotensin II stimulation. keywords: age; cases; covid-19; disease; mortality; patients; preconditions; risk; study cache: cord-294910-gnc04ax1.txt plain text: cord-294910-gnc04ax1.txt item: #302 of 449 id: cord-295575-zgta5ah8 author: Howard, Evin title: The Impact of Ambient Environmental Exposures to Microbial Products on Asthma Outcomes from Birth to Childhood date: 2019-11-28 words: 6939 flesch: 44 summary: Genetic variations among individuals also mitigate the effects of microbial products on asthma development and symptom severity. Viral products are related to asthma-associated hospital admissions; and the climate and patient genetics can also temper or intensify the relationships between microbial products, asthma development, and asthma symptom severity. keywords: age; asthma; children; development; endotoxin; exposure; fungal; products; studies; study cache: cord-295575-zgta5ah8.txt plain text: cord-295575-zgta5ah8.txt item: #303 of 449 id: cord-295786-cpuz08vl author: Castillo-Sánchez, Gema title: Suicide Risk Assessment Using Machine Learning and Social Networks: a Scoping Review date: 2020-11-09 words: 7126 flesch: 52 summary: key: cord-295786-cpuz08vl authors: Castillo-Sánchez, Gema; Marques, Gonçalo; Dorronzoro, Enrique; Rivera-Romero, Octavio; Franco-Martín, Manuel; De la Torre-Díez, Isabel title: Suicide Risk Assessment Using Machine Learning and Social Networks: a Scoping Review date: 2020-11-09 journal: J Med Syst DOI: 10.1007/s10916-020-01669-5 sha: doc_id: 295786 cord_uid: cpuz08vl According to the World Health Organization (WHO) report in 2016, around 800,000 of individuals have committed suicide. The authors have performed a systematic review to identify relevant papers that use suicide risk assessment models in social networks. keywords: authors; data; information; models; networks; risk; studies; study; suicide; techniques cache: cord-295786-cpuz08vl.txt plain text: cord-295786-cpuz08vl.txt item: #304 of 449 id: cord-295806-imuk73xa author: Ramirez-Moreno, J. M. title: Mask-associated de novo headache in healthcare workers during the Covid-19 pandemic. date: 2020-08-11 words: 3990 flesch: 46 summary: Finally, a study of 212 health professionals assessing demographic factors, time of N-95 mask use and the existence of previous headaches showed a relatively high prevalence of mask headache among health workers who worked in high-risk areas during the 2003 SARS epidemic [10] . In addition, they reported that headache was clearly different from other headaches suffered in 64.6% of the cases. keywords: headache; health; mask; novo; stress; study; use; workers cache: cord-295806-imuk73xa.txt plain text: cord-295806-imuk73xa.txt item: #305 of 449 id: cord-296491-467nrx6d author: O’Brien, Bridget C. title: Pause, Persist, Pivot: Key Decisions Health Professions Education Researchers Must Make About Conducting Studies During Extreme Events date: 2020-06-09 words: 3869 flesch: 46 summary: Acad Med DOI: 10.1097/acm.0000000000003535 sha: doc_id: 296491 cord_uid: 467nrx6d When extreme events occur, some research becomes a clear priority, but what becomes of all other research? Extreme events such as earthquakes, hurricanes, political conflicts, and pandemics are occurrences that, relative to some class of related occurrences, are either notable, rare, unique, profound, or otherwise significant in terms of their impacts, effects, or outcomes. keywords: data; event; findings; persist; research; researchers; study cache: cord-296491-467nrx6d.txt plain text: cord-296491-467nrx6d.txt item: #306 of 449 id: cord-296888-z5x6zkht author: Hailay, Abrha title: The burden, admission, and outcomes of COVID-19 among asthmatic patients in Africa: protocol for a systematic review and meta-analysis date: 2020-09-04 words: 2766 flesch: 43 summary: Describe planned method of extracting data from reports (e.g., piloting forms, done independently, in duplicate), any processes for obtaining and confirming data from investigators Data items 12 List and define all variables for which data will be sought (e.g., PICO items, funding sources), any pre-planned data assumptions and simplifications Outcomes and prioritization 13 List and define all outcomes for which data will be sought, including prioritization of main and additional outcomes, with rationale Risk of bias in individual studies 14 Describe anticipated methods for assessing risk of bias of individual studies, including whether this will be done at the outcome or study level, or both; state how this information will be used in data synthesis Describe criteria under which study data will be quantitatively synthesized 15b If data are appropriate for quantitative synthesis, describe planned summary measures, methods of handling data, and methods of combining data from studies, including any Studies that have not clarified the requirements for the COVID-19 outcome level; studies that have not been conducted in humans, qualitative studies, studies that lack valid data required to determine the outcome will not be included. A tool developed by Hoy et al. for prevalence studies will be used to evaluate the likelihood of bias and quality of studies included in this review [20] . keywords: covid-19; data; outcome; patients; review; studies; study cache: cord-296888-z5x6zkht.txt plain text: cord-296888-z5x6zkht.txt item: #307 of 449 id: cord-298257-uptgv2xv author: Cheng, Wenwen title: Efficacy and Safety of Corticosteroid Treatment in Patients With COVID-19: A Systematic Review and Meta-Analysis date: 2020-09-09 words: 5809 flesch: 37 summary: A series of clinical studies demonstrated that low-dose or physiological-dose corticosteroid treatments in patients with septic shock caused by pulmonary infection significantly shortened the length of ICU hospital stay and reversed the progression of shock (Rhodes et al., 2017; Marik, 2018) . Recently, emerging evidence from the initial clinical trial revealed a clear benefit of dexamethasone in patients with COVID-19 Fadel et al., 2020) . keywords: cohort; corticosteroid; covid-19; et al; group; patients; studies; study cache: cord-298257-uptgv2xv.txt plain text: cord-298257-uptgv2xv.txt item: #308 of 449 id: cord-298265-elbnzgx6 author: Mutua, Victoria title: A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics date: 2020-08-01 words: 10425 flesch: 29 summary: formation Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens How neutrophils kill microbes Neutrophil extracellular traps (NET) induced by different stimuli: a comparative proteomic analysis Neutrophil extracellular traps profiles in patients with incident systemic lupus erythematosus and lupus nephritis Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps NLRP3 activation induced by neutrophil extracellular traps sustains inflammatory response in the diabetic wound The influence of hyperglycemia on neutrophil extracellular trap formation and endothelial Pathogenesis and therapy of psoriasis Neutrophil extracellular traps and their role in the development of chronic inflammation and autoimmunity Regulating neutrophil apoptosis: new players enter the game Mechanisms of B cell autoimmunity in SLE Systemic lupus erythematosus Immunological pathogenesis and treatment of systemic lupus erythematosus Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus Review article neutrophil function in an inflammatory milieu of rheumatoid arthritis Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis Proinflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis Rev Médica del Diabetes primes neutrophils to undergo NETosis, which impairs wound healing The adipose tissue as a source of vasoactive factors Adipocytes properties and crosstalk with immune system in obesity-related inflammation Neutrophil extracellular traps and cardiovascular diseases: an update Increased plasmatic NETs by-products in patients in severe obesity In vivo and in vitro studies on the roles of neutrophil extracellular traps during secondary pneumococcal pneumonia after primary pulmonary influenza infection Effect of high-fat diet on the formation of pulmonary neutrophil extracellular traps during influenza pneumonia in BALB/c mice Role of thromboxane-dependent platelet activation in venous thrombosis: aspirin effects in mouse model Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury Aspirin-triggered 15-epi-lipoxin a4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice Activation of platelet function through G protein-coupled receptors Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury Aspirin, but NotTirofiban displays protective effects in endotoxin induced lung injury Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation Regulation of neutrophil extracellular trap formation by anti-inflammatory drugs Mechanisms of action of cyclosporine Cyclosporine: a review Cyclosporine in veterinary dermatology Molecular mechanisms of action of some immunosuppressive drugs Efficient neutrophil extracellular trap induction requires mobilization of both intracellular and extracellular calcium pools and is modulated by cyclosporine A. PLoS One:9 Posttransplant infections in the tropical countries Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer AA et alPeptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice NETosis delays diabetic wound healing in mice and humans keywords: activation; cells; conditions; damage; disease; effects; extracellular; formation; histones; human; inflammation; inhibition; injury; mice; netosis; nets; neutrophil; patients; production; protein; studies; traps; treatment cache: cord-298265-elbnzgx6.txt plain text: cord-298265-elbnzgx6.txt item: #309 of 449 id: cord-300064-t3qexner author: Kumar, Krishan title: The psychological impact of COVID-19 pandemic and lockdown on the migrant workers: A cross-sectional survey date: 2020-06-20 words: 1886 flesch: 52 summary: A global measure of perceived stress Psychological impact of Lockdown 'as COVID-19 social distancing strategy': An online Survey from India Occupational health outcomes among international migrant workers: a systematic review and meta-analysis Diagnostic and Clinical Utility of the GAD-2 for Screening Anxiety Symptoms in Individuals With Multiple Sclerosis Indian migrant workers during the COVID-19 pandemic The Patient Health Questionnaire-2: validity of a two-item depression screener Review of the Psychometric Evidence of the Perceived Stress Scale National Mental Health Survey of India 2015-2016 Mental health of migrant laborers in COVID-19 pandemic and lockdown: Lockdown brought the lives of migrant workers to a standstill, as neither have they had any work to do, nor were they able to travel back to their native places. keywords: depression; health cache: cord-300064-t3qexner.txt plain text: cord-300064-t3qexner.txt item: #310 of 449 id: cord-300078-svu06v9c author: Haghani, Milad title: Covid-19 pandemic and the unprecedented mobilisation of scholarly efforts prompted by a health crisis: Scientometric comparisons across SARS, MERS and 2019-nCov literature date: 2020-06-01 words: 6373 flesch: 43 summary: Covid-19 studies seem to have been distributed across a broader variety of journals and subject areas. Covid-19 studies also display the involvement of authors from a broader variety of countries compared to SARS and MRS. keywords: cluster; covid-19; items; literature; mers; number; research; sars; studies; terms cache: cord-300078-svu06v9c.txt plain text: cord-300078-svu06v9c.txt item: #311 of 449 id: cord-300176-lurzcliy author: van Mol, Margo M. C. title: Developing and testing a nurse-led intervention to support bereavement in relatives in the intensive care (BRIC study): a protocol of a pre-post intervention study date: 2020-08-18 words: 5646 flesch: 39 summary: Bereaved relatives may develop complicated grief as a consequence of this burdensome situation; however, little is known about appropriate options in quality care supporting bereaved relatives and the prevalence and predictors of complicated grief in bereaved relatives of deceased ICU patients in the Netherlands. The aim of this study is to develop and implement a multicomponent bereavement support intervention for relatives of deceased ICU patients and to evaluate the effectiveness of this intervention on complicated grief, anxiety, depression and posttraumatic stress in bereaved relatives. keywords: bereavement; care; death; grief; icu; intervention; patients; quality; relatives; study; support cache: cord-300176-lurzcliy.txt plain text: cord-300176-lurzcliy.txt item: #312 of 449 id: cord-300320-07tdrd4w author: Siordia, Juan A. title: Systematic and Statistical Review of Coronavirus Disease 19 Treatment Trials date: 2020-07-15 words: 4849 flesch: 42 summary: key: cord-300320-07tdrd4w authors: Siordia, Juan A.; Bernaba, Michael; Yoshino, Kenji; Ulhaque, Abid; Kumar, Sooraj; Bernaba, Mario; Bergin, Edward title: Systematic and Statistical Review of Coronavirus Disease 19 Treatment Trials date: 2020-07-15 journal: SN Compr Clin Med DOI: 10.1007/s42399-020-00399-6 sha: doc_id: 300320 cord_uid: 07tdrd4w The following systematic review and meta-analysis compile the current data regarding human controlled COVID-19 treatment trials. The following systematic and statistical review assesses the current evidence regarding human controlled COVID-19 treatment trials. keywords: arbidol; covid-19; effects; favipiravir; heparin; hydroxychloroquine; lopinavir; patients; ritonavir; studies; treatment cache: cord-300320-07tdrd4w.txt plain text: cord-300320-07tdrd4w.txt item: #313 of 449 id: cord-300465-19euup51 author: Paniagua-Avila, Alejandra title: Evaluating a multicomponent program to improve hypertension control in Guatemala: study protocol for an effectiveness-implementation cluster randomized trial date: 2020-06-09 words: 4900 flesch: 35 summary: Normas de Atencion Salud Integral para primero y segundo nivel Evaluation of a pilot hypertension management programme for Guatemalan adults Measurement of blood pressure in humans: a scientific statement from the Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda Effect of a community health worker-led multicomponent intervention on blood pressure control in low-income patients in Argentina: a randomized clinical trial Comprehensive approach for hypertension control in low-income populations: rationale and study design for the hypertension control program in argentina RE-AIM Planning and evaluation framework: adapting to new science and practice with a 20-year review Using the Practical, Robust Implementation and Sustainability Model (PRISM) to qualitatively assess multilevel contextual factors to help plan, implement, evaluate, and disseminate health services programs Evaluating the public health impact of health promotion interventions: the RE-AIM framework Cost-effectiveness analysis alongside clinical trials II-An ISPOR Good Research Practices Task Force report Intervention costs will include fixed costs such as education of health providers and salary of auxiliary nurses, and variable costs such as electronic BP monitors. keywords: care; control; health; hypertension; implementation; intervention; nurses; participants; patients; program; study cache: cord-300465-19euup51.txt plain text: cord-300465-19euup51.txt item: #314 of 449 id: cord-301143-o12we0uw author: Andualem, Atsedemariam title: Adherence to Lifestyle Modifications and Associated Factors Among Adult Hypertensive Patients Attending Chronic Follow-Up Units of Dessie Referral Hospital, North East Ethiopia, 2020 date: 2020-10-23 words: 6076 flesch: 41 summary: From the available literature search there is no study that showed lifestyle modifications adherence and associated factors in the study area despite its advantages. Patients who were found during the study period in the study area who fulfilled the inclusion criteria were included in the study exclusively for lifestyle modification adherence at Dessie referral hospital. keywords: adherence; data; factors; hypertension; lifestyle; modifications; patients; respondents; self; study cache: cord-301143-o12we0uw.txt plain text: cord-301143-o12we0uw.txt item: #315 of 449 id: cord-301393-d1duepnb author: Wolfensberger, Aline title: Implementation and evaluation of a care bundle for prevention of non-ventilator-associated hospital-acquired pneumonia (nvHAP) – a mixed-methods study protocol for a hybrid type 2 effectiveness-implementation trial date: 2020-08-17 words: 5973 flesch: 28 summary: To identify which factors in the implementation setting are associated with the actual degree of local implementation of the nvHAP bundle The study is conducted at the University Hospital Zurich (UHZ), Switzerland, a 950-bed tertiary-care teaching hospital covering all medical specialties except paediatrics and orthopaedics. On the hospital level the three periods are defined as follows: 1) hospital baseline period, before starting implementation in the first department; 2) hospital implementation period, from the beginning of the implementation period of the first department until end of implementation period of the last included department; 3) hospital intervention period following the hospital implementation period. keywords: bundle; data; department; hospital; implementation; indicators; nvhap; period; pneumonia; prevention; process; study cache: cord-301393-d1duepnb.txt plain text: cord-301393-d1duepnb.txt item: #316 of 449 id: cord-301805-sb0ij8k7 author: Fuentes, Blanca title: Glycemic variability: prognostic impact on acute ischemic stroke and the impact of corrective treatment for hyperglycemia. The GLIAS-III translational study date: 2020-11-04 words: 3839 flesch: 37 summary: Intervention After the participants sign the informed consent form, they will be implanted a CGM subcutaneously to monitor glucose levels for 96 h. These devices are of common use in the management of type 1 diabetes and they have been proven to be safe in stroke patients when used in research studies. Recruitment started on Glycemic variability: a strong independent predictor of mortality in critically ill patients Glucose variability is associated with intensive care unit mortality* Glycemic variability and acute ischemic stroke: the missing link? Effects of glycemic variability and hyperglycemia in acute ischemic stroke on post-stroke cognitive impairments Range of glucose as a glycemic variability and 3-month outcome in diabetic patients with acute ischemic stroke Management of hyperglycemia in patients with acute ischemic stroke: comparison of two strategies Outcome prediction in acute stroke patients by continuous glucose monitoring Post stroke dysglycemia and acute infarct volume growth: a study using continuous glucose monitoring Variability of blood glucose concentration and short-term mortality in critically ill patients Increased glycemic variability is independently associated with length of stay andmortality in noncritically ill hospitalized patients Glycemia in Acute Stroke II study: a call to improve post-stroke hyperglycemia management in clinical practice Sliding scale insulin-time to stop sliding Various blood glucose parameters that indicate hyperglycemia after intravenous thrombolysis in acute ischemic stroke could predict worse outcome Glucose and stroke: What about glycemic variability? Clinical review: Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults Continuous glucose monitoring in insulintreated patients in non-ICU settings Glucose variability; does it matter? keywords: acute; content; follow; glucose; hyperglycemia; manuscript; patients; revision; stroke; study cache: cord-301805-sb0ij8k7.txt plain text: cord-301805-sb0ij8k7.txt item: #317 of 449 id: cord-302833-6kntd89t author: Radonovich, Lewis J. title: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel date: 2016-06-02 words: 5093 flesch: 32 summary: key: cord-302833-6kntd89t authors: Radonovich, Lewis J.; Bessesen, Mary T.; Cummings, Derek A.; Eagan, Aaron; Gaydos, Charlotte; Gibert, Cynthia; Gorse, Geoffrey J.; Nyquist, Ann-Christine; Reich, Nicholas G.; Rodrigues-Barradas, Maria; Savor-Price, Connie; Shaffer, Ronald E.; Simberkoff, Michael S.; Perl, Trish M. title: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel date: 2016-06-02 journal: BMC Infect Dis DOI: 10.1186/s12879-016-1494-2 sha: doc_id: 302833 cord_uid: 6kntd89t BACKGROUND: Although N95 filtering facepiece respirators and medical masks are commonly used for protection against respiratory infections in healthcare settings, more clinical evidence is needed to understand the optimal settings and exposure circumstances for healthcare personnel to use these devices. keywords: healthcare; illness; infections; influenza; laboratory; masks; n95; participants; protection; respect; respirators; study; transmission cache: cord-302833-6kntd89t.txt plain text: cord-302833-6kntd89t.txt item: #318 of 449 id: cord-303187-ny4qr2a2 author: Belo, Vinícius Silva title: Abundance, survival, recruitment and effectiveness of sterilization of free-roaming dogs: A capture and recapture study in Brazil date: 2017-11-01 words: 7692 flesch: 39 summary: Editora Ministério da Saúde A general methodology for the analysis of capture-recapture experiments in open populations U-CARE: utilities for performing goodness of fit tests and manipulating capture-recapture data Estimability and likelihood inference for generalized linear mixed models using data cloning Model Selection and Multi-Model Inference: A Practical Information-Theoretic Approach Information-theoretic model selection and model averaging for closed-population capture-recapture studies Studies on dog population and its implication for rabies control Assessing demographic and epidemiologic parameters of rural dog populations in India during mass vaccination campaigns A survey of the dog population in rural Bangladesh Free-roaming dog population estimation and status of the dog population management and rabies control program in Dhaka City Demography of domestic dogs in rural and urban areas of the Coquimbo region of Chile and implications for disease transmission Spacing and social organization: Urban stray dogs revisited Is survivorship a better fitness surrogate than fecundity? Fecundity and longevity of roaming dogs in Jaipur Population ecology of free-ranging urban dogs in West Bengal Age, sex, density, winter weather, and population crashes in Soay sheep Sex-and age-dependent effects of population density on life history traits of red deer Cervus elaphus in a temperate forest The Evolution of Parental Care Effects of maternal care on the lifetime reproductive success of females in a neotropical harvestman A seroepidemiologic survey of canine visceral leishmaniosis among apparently healthy dogs in Croatia Persistent Instability and Population Regulation in Soay Sheep Temporal changes in key factors and key age groups influencing the population dynamics of female red deer Assessing the impact of climate variation on survival in vertebrate populations Complex interplay between intrinsic and extrinsic drivers of long-term survival trends in southern elephant seals Loss of density-dependence and incomplete control by dominant breeders in a territorial species with density outbreaks Stochasticity and Determinism: How Density-Independent and Density-Dependent Processes Affect Population Variability Bayesian Inference on the Effect of Density Dependence and Weather on a Guanaco Population from Chile Density-Dependent Spacing Behaviour and Activity Budget in Pregnant, Domestic Goats (Capra hircus) Such information on the dynamics of free-ranging dogs are useful for informing control interventions of unrestricted dog populations and against canine visceral leishmaniasis and rabies, both neglected tropical diseases endemic to various countries. keywords: animals; areas; capture; control; dogs; dynamics; estimates; model; parameters; population; probability; recruitment; sterilization; study; survival cache: cord-303187-ny4qr2a2.txt plain text: cord-303187-ny4qr2a2.txt item: #319 of 449 id: cord-303300-89v1weno author: Sauter, Marian title: Building, Hosting and Recruiting: A Brief Introduction to Running Behavioral Experiments Online date: 2020-04-24 words: 5293 flesch: 44 summary: The First Single Application for the Entire DevOps Lifecycle-GitLab | GitLab Just another tool for online studies (JATOS): An easy solution for setup and management of web servers supporting online studies Another Tool for Online Studies Subject pool recruitment procedures: Organizing experiments with ORSEE Sona Systems: Cloud-based Subject Pool Software for Universities Running experiments on amazon mechanical turk Evaluating Amazon's mechanical turk as a tool for experimental behavioral research Prolific | Online Participant Recruitment for Surveys and Market Research Prolific.ac-A subject pool for online experiments Panel Management Software-Recruit, Target, & Save Money | Qualtrics Survey Solutions for Researchers Introduction to Online Experiments The pitfall of experimenting on the web: How unattended selective attrition leads to surprising (yet false) research conclusions López-de-Ipiña, D. Presentation accuracy of the web revisited: Animation methods in the HTML5 era Presentation and response timing accuracy in Adobe Flash and HTML5/JavaScript Web experiments Best practices: Two Web-browser-based methods for stimulus presentation in behavioral experiments with high-resolution timing requirements The Timing Mega-Study: Comparing a Range of Experiment Generators, Both Lab-Based and Online Online Timing Accuracy and Precision: A comparison of platforms, browsers, and participant's devices Online psychophysics: Reaction time effects in cognitive experiments Is There a cost to convenience? However, they found that they could collect data Finally, online experimental studies should be short. keywords: data; experiments; lab; online; participants; solutions; studies; study; testing; web cache: cord-303300-89v1weno.txt plain text: cord-303300-89v1weno.txt item: #320 of 449 id: cord-304510-sfhwaqfr author: Henssler, Jonathan title: Mental health effects of infection containment strategies: quarantine and isolation—a systematic review and meta-analysis date: 2020-10-06 words: 5311 flesch: 33 summary: key: cord-304510-sfhwaqfr authors: Henssler, Jonathan; Stock, Friederike; van Bohemen, Joris; Walter, Henrik; Heinz, Andreas; Brandt, Lasse title: Mental health effects of infection containment strategies: quarantine and isolation—a systematic review and meta-analysis date: 2020-10-06 journal: Some studies [29, 30] did not find negative mental health effects in isolation of 1-3 days duration, whereas others [26, 31, 32] did. keywords: depression; disorders; effects; health; isolation; outcomes; persons; quarantine; risk; studies cache: cord-304510-sfhwaqfr.txt plain text: cord-304510-sfhwaqfr.txt item: #321 of 449 id: cord-306391-g7dhwogk author: Fernando, Shannon M. title: Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis date: 2020-04-18 words: 4467 flesch: 32 summary: Impact of diagnostic criteria on the incidence of ventilator-associated pneumonia A national survey of the diagnosis and management of suspected ventilator-associated pneumonia Ventilator-associated pneumonia: overdiagnosis and treatment are common in medical and surgical intensive care units Clinical pulmonary infection score for ventilator-associated pneumonia: accuracy and inter-observer variability Diagnosis of ventilator-associated pneumonia: a systematic review of the literature Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Preferred reporting items for a systematic review and meta-analysis of diagnostic test accuracy studies: the PRISMA-DTA statement Cochrane handbook for systematic reviews of diagnostic test accuracy Systematic reviews of diagnostic test accuracy Prognostic accuracy of the quick sequential organ failure assessment for mortality in patients with suspected infection: a systematic review and meta-analysis Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis Surveillance search techniques identified the need to update systematic reviews QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations User guide version 1.3. Two reviewers (SMF and A. Tran) independently assessed risk-of-bias of included studies, using the Quality Assessment of Diagnostic Accuracy Studies (QUA-DAS-2) tool [25] . keywords: accuracy; patients; pneumonia; sensitivity; specificity; studies; vap cache: cord-306391-g7dhwogk.txt plain text: cord-306391-g7dhwogk.txt item: #322 of 449 id: cord-307038-c58mzcu9 author: Shukla, Nagesh title: A Review of Models Used for Investigating Barriers to Healthcare Access in Australia date: 2020-06-08 words: 8791 flesch: 38 summary: The index of rural access: An innovative integrated approach for measuring primary care access Access to primary health care services for Indigenous peoples: A framework synthesis An evaluation of access to health care services along the rural-urban continuum in Canada Accessing doctors at times of need-measuring the distance tolerance of rural residents for health-related travel Spatial accessibility of primary health care utilising the two step floating catchment area method: An assessment of recent improvements A new index of access to primary care services in rural areas Equity of access in the spatial distribution of GPs within an Australian metropolitan city Measuring spatial accessibility to primary health care services: Utilising dynamic catchment sizes Index of access: A new innovative and dynamic tool for rural health service and workforce planning. The vast geographical area of the country, varied residential locations and their uneven distribution of population, network of roads and traffic conditions and the allocation of hospital resources lead to an imbalance of health service access for the people [12] . keywords: access; accessibility; areas; barriers; cancer; distance; health; healthcare; population; rural; services; studies; study cache: cord-307038-c58mzcu9.txt plain text: cord-307038-c58mzcu9.txt item: #323 of 449 id: cord-307202-iz1bo218 author: Shaw, Dominick title: Asthma date: 2014-05-02 words: 19202 flesch: 32 summary: The aim of asthma treatment is to improve symptoms, maintain lung function, and prevent exacerbations. Although there are several pharmacological options for asthma treatment (see Figure 28 .4), the two main classes remain bronchodilators (short-or long-acting) and corticosteroids. keywords: airway; approaches; association; asthma; cells; children; control; corticosteroid; disease; effects; exacerbations; factors; fev; function; gene; inflammation; leukotriene; lung; montelukast; patients; polymorphisms; protein; receptor; response; snps; studies; study; symptoms; therapy; treatment; use cache: cord-307202-iz1bo218.txt plain text: cord-307202-iz1bo218.txt item: #324 of 449 id: cord-307263-znuqdzdp author: Sun, Niuniu title: A Qualitative Study on the Psychological Experience of Caregivers of COVID-19 Patients date: 2020-04-08 words: 4483 flesch: 47 summary: Psychological research as the phenomenologist views it Working experiences of nurses during the Middle East respiratory syndrome outbreak Facing SARS: psychological impacts on SARS team nurses and psychiatric services in a Taiwan general hospital Nat ional Healt h Commission of the People's Republic o f China. Situation Report -39 Update on pneumonia of new coronavirus infect ion as of 24:00 on China Disease Control Report: more than 3,000 medical staff infected with new crown virus Ethical and legal challenges associated wit h disaster nursing Nurses' beliefs about public healt h emergencies: fear of abandonment SARS: caring for patients in Hong Kong Nurses' experiences of care for patients wit h Middle East respiratory syndrome-coronavirus in South Korea Healt hcare worker semotions, perceived stressors and coping strategies during MERS-CoV outbreak Sources and symptoms of stress among nurses in the first Chinese ant i-Ebola medical team during the Sierra Leone aid mission: A qualitat ive study New Zealand nurses percept ions of caringfor patients with influenza A (H1N1) Prevalence of psychiatric morbidit y and psychological adaptat ion of the nurses in a structured SARS caring unit during outbreak: A prospect ive and periodic assessment study in Taiwan keywords: covid-19; emotions; epidemic; experience; health; nurses; patients; stress; study cache: cord-307263-znuqdzdp.txt plain text: cord-307263-znuqdzdp.txt item: #325 of 449 id: cord-307758-a4sgt66g author: Hong, Ching-Ye title: Acute respiratory symptoms in adults in general practice date: 2004-06-17 words: 3928 flesch: 52 summary: key: cord-307758-a4sgt66g authors: Hong, Ching-Ye; Lin, Raymond TP; Tan, Elaine SL; Chong, Phui-Nah; Tan, Yvette SL; Lew, Yii-Jen; Loo, Liat-Hui title: Acute respiratory symptoms in adults in general practice date: 2004-06-17 journal: The purpose of this study was to determine the infective aetiology in patients who presented to primary care doctors with acute respiratory symptoms. keywords: culture; group; infections; pathogens; patients; pcr; study; symptoms; virus cache: cord-307758-a4sgt66g.txt plain text: cord-307758-a4sgt66g.txt item: #326 of 449 id: cord-308964-y18nru1d author: Couper, Keith title: COVID-19 in cardiac arrest and infection risk to rescuers: a systematic review date: 2020-04-20 words: 3366 flesch: 37 summary: The aim of this review was to identify the potential risk of transmission associated with key interventions (chest compressions, defibrillation, cardiopulmonary resuscitation) to inform international treatment recommendations. We did not find any direct evidence that chest compressions or defibrillation either are or are not associated with aerosol generation or transmission of infection. keywords: chest; compressions; defibrillation; evidence; risk; studies; study; transmission cache: cord-308964-y18nru1d.txt plain text: cord-308964-y18nru1d.txt item: #327 of 449 id: cord-309122-9dfyjpid author: Sato, Akiko title: Reviews on common objectives and evaluation indicators for risk communication activities from 2011 to 2017 date: 2020-08-25 words: 5548 flesch: 34 summary: key: cord-309122-9dfyjpid authors: Sato, Akiko; Honda, Kaori; Ono, Kyoko; Kanda, Reiko; Hayashi, Takehiko I.; Takeda, Yoshihito; Takebayashi, Yoshitake; Kobayashi, Tomoyuki; Murakami, Michio title: Reviews on common objectives and evaluation indicators for risk communication activities from 2011 to 2017 date: 2020-08-25 journal: PeerJ DOI: 10.7717/peerj.9730 sha: doc_id: 309122 cord_uid: 9dfyjpid BACKGROUND: Risk communication is widely accepted as a significant factor for policy makers, academic researchers, and practitioners in diverse fields. However, there remains a lack of comprehensive knowledge about how risk communication is currently conducted across fields and about the way risk communication is evaluated. keywords: activities; change; communication; crisis; evaluation; field; food; health; information; risk; safety; study cache: cord-309122-9dfyjpid.txt plain text: cord-309122-9dfyjpid.txt item: #328 of 449 id: cord-310027-846vp7ii author: Ma, Lin-Lu title: Coronavirus Disease 2019 Related Clinical Studies: A Cross-Sectional Analysis date: 2020-09-02 words: 4252 flesch: 43 summary: We did an electronic search of COVID-19 related clinical studies registered between December 1, 2019 and February 21, 2020 (updated to May 28, 2020) from the ClinicalTrials.gov, and collected registration information, study details, recruitment status, characteristics of the subjects, and relevant information about the trial implementation process. Registration of COVID-19 related clinical studies is ongoing. keywords: coronavirus; covid-19; patients; registration; studies; study; treatment; trials cache: cord-310027-846vp7ii.txt plain text: cord-310027-846vp7ii.txt item: #329 of 449 id: cord-310215-11srk6iq author: Bielinis, Ernest title: A Novel Anti-Environmental Forest Experience Scale to Predict Preferred Pleasantness Associated with Forest Environments date: 2020-09-16 words: 8742 flesch: 46 summary: There are two promising theories for determining the fundamental psychological indices of an individual which might be usable for prediction of the level of psychological relaxation experienced in forest environments or in virtual reality. However, none of the domains of the Amoebic Self Scale exactly connect with phenomena that occur in forest environments. keywords: aefes; environment; forest; forest environment; landscape; participants; pleasantness; preferred; scale; self; study cache: cord-310215-11srk6iq.txt plain text: cord-310215-11srk6iq.txt item: #330 of 449 id: cord-311260-eyvaazfj author: Rao, Ghanta N. title: Refinement of long-term toxicity and carcinogenesis studies() date: 2004-09-27 words: 4476 flesch: 38 summary: Duration of chemical carcinogenesis studies in rodents usually covers a major portion of the life span. The median life span (50% survival) of rodent species and strains used for chemical carcinogenesis studies is 20 to 30 months and, therefore, studies lasting 2 1 to 27 months will cover 60-80% of the life span, assuming 90% mortality is close to the life span. keywords: animals; carcinogenesis; chemicals; lesions; mice; months; rats; studies cache: cord-311260-eyvaazfj.txt plain text: cord-311260-eyvaazfj.txt item: #331 of 449 id: cord-313616-81u4nidw author: Davis, G. S. title: Spatial and temporal analyses to investigate infectious disease transmission within healthcare settings date: 2014-04-30 words: 7437 flesch: 18 summary: in an Italian general intensive care unit An outbreak of mupirocin-resistant Staphylococcus aureus on a dermatology ward associated with an environmental reservoir Nosocomial outbreak of gastroenteritis due to Salmonella senftenberg Use of interrepeat PCR fingerprinting to investigate an Acinetobacter baumannii outbreak in an intensive care unit Epidemiology and clinical characteristics of parainfluenza virus 3 outbreak in a haematooncology unit Low frequency of endemic patient-to-patient transmission of antibioticresistant Gram-negative bacilli in a pediatric intensive care unit Origin and transmission of methicillin-resistant Staphylococcus aureus in an endemic situation: differences between geriatric and intensive-care patients The role of interventional molecular epidemiology in controlling clonal clusters of multidrug resistant Pseudomonas aeruginosa in critically ill cancer patients Nosocomial transmission in simultaneous outbreaks of hepatitis C and B virus infections in a hemodialysis center Investigation and control of an outbreak of imipenem-resistant Acinetobacter baumannii infection in a pediatric intensive care unit Nosocomial acquisition of Clostridium difficile infection A cluster of nosocomial Klebsiella oxytoca bloodstream infections in a university hospital Nosocomial outbreak of staphylococcal scalded skin syndrome in neonates: epidemiological investigation and control Outbreak of nosocomial urinary tract infections due to Pseudomonas aeruginosa in a paediatric surgical unit associated with tap-water contamination Invasive aspergillosis e clusters and sources Nosocomial legionellosis associated with aspiration of nasogastric feedings diluted in tap water Outbreak of pseudobacteremia due to multidrug-susceptible Enterococcus faecium Frequency and diversity of molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients of a South West German teaching hospital A nosocomial outbreak of Candida parapsilosis in southern Sweden verified by genotyping Hospital transmission of multidrug-resistant Mycobacterium tuberculosis in Rosario Molecular epidemiology of a hepatitis C virus outbreak in a haemodialysis unit An outbreak of group A streptococcal infection among health care workers Spread of methicillin-resistant Staphylococcus aureus in a hospital after exposure to a health care worker with chronic sinusitis Molecular epidemiology of endemic Clostridium difficile infection Norovirus in the hospital setting: virus introduction and spread within the hospital environment An outbreak of methicillinresistant Staphylococcus aureus infection in patients of a pediatric intensive care unit and high carriage rate among health care workers An investigation of the spread of gentamicin resistance in a district general hospital Epidemiology and control of an outbreak of vancomycin-resistant enterococci in the intensive care units Outbreak of communityacquired methicillin-resistant Staphylococcus aureus skin infections among health care workers in a cancer center Outbreak of extendedspectrum beta-lactamase-producing Klebsiella oxytoca infections associated with contaminated handwashing sinks Successful control of a hospital-wide vancomycin-resistant Enterococcus faecium outbreak in France Cluster of cases of invasive aspergillosis in a transplant intensive care unit: evidence of person-to-person airborne transmission Tightly clustered outbreak of group A streptococcal disease at a long-term care facility A hospital epidemic of vancomycin-resistant enterococcus: risk factors and control An outbreak of acute gastroenteritis in a geriatric long-term-care facility: combined application of epidemiological and molecular diagnostic methods A bronchofiberoscopy-associated outbreak of multidrug-resistant Acinetobacter baumannii in an intensive care unit in Beijing, China Nosocomial infection by gentamicin-resistant Streptococcus faecalis: an epidemiologic study Changing pattern of antibiotic resistance in methicillin-resistant Staphylococcus aureus from German hospitals Modelling the impact of antibiotic use and infection control practices on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus: a time-series analysis Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients Temporal effects of infection control practices and the use of antibiotics on the incidence of MRSA Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile A time-series analysis of Clostridium difficile and its seasonal association with influenza Detecting related cases of bloodstream infections using time-interval distribution modelling Analysis of hospital infection surveillance data Others examined annual trends, were case studies or review papers, or focused on non-healthcare settings. keywords: analysis; care; cases; control; data; healthcare; hospital; infection; outbreak; patients; studies; time; transmission; unit; use cache: cord-313616-81u4nidw.txt plain text: cord-313616-81u4nidw.txt item: #332 of 449 id: cord-313783-cfcfiyju author: Pinna, Fábio de Rezende title: Olfaction and COVID: The little we Know and what else we need to know date: 2020-06-15 words: 858 flesch: 48 summary: Sudden and Complete Olfactory Loss Function as a Possible Symptom of COVID-19 Olfactory and gustatory dysfunctions as a clinical presentation of mild-tomoderate forms of the coronavirus disease (COVID-19): a multicenter European study Association of chemosensory dysfunction and Covid-19 in patients presenting with influenza-like symptoms Objective evaluation of anosmia and ageusia in COVID-19 patients: Single-center experience on 72 cases SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection 2 More extensive sample sizes studies would have detected differences in subgroups that this article from the Middle East might have failed to do. keywords: covid-19; patients; studies cache: cord-313783-cfcfiyju.txt plain text: cord-313783-cfcfiyju.txt item: #333 of 449 id: cord-314288-6vh7dvad author: Leibovici, L. title: Submissions and publications in Corona times date: 2020-05-15 words: 1094 flesch: 52 summary: Observational studies: Now we have a good idea from published studies on the clinical course of COVID-19, and further descriptions of small groups of patients have little to add. However systematic reviews of observational studies, and especially meta-analyses of such studies assessing the efficiency of drugs, are problematic. keywords: covid-19; patients; studies cache: cord-314288-6vh7dvad.txt plain text: cord-314288-6vh7dvad.txt item: #334 of 449 id: cord-314449-ukqux772 author: Curtis, L.T. title: Prevention of hospital-acquired infections: review of non-pharmacological interventions date: 2008-06-02 words: 9002 flesch: 34 summary: 11 Pathogens from hospital water are another underappreciated and underdiagnosed source of hospital infection. Contaminated environmental surfaces (such as bedside rails) are also an under-recognised source of hospital infections. keywords: air; analysis; catheters; cleaning; control; hand; hospital; infections; interventions; mrsa; patients; rates; risk; rooms; studies; study; urinary; use; water cache: cord-314449-ukqux772.txt plain text: cord-314449-ukqux772.txt item: #335 of 449 id: cord-314908-kp2jznwb author: Roczniewska, Marta title: I believe I can craft! introducing Job Crafting Self-Efficacy Scale (JCSES) date: 2020-08-10 words: 9303 flesch: 49 summary: JCSE explained unique variance in job crafting behaviors over and above general self-efficacy, and was more important in predicting job crafting than contextual factors. In the meta-analysis, general self-efficacy has been positively linked with job crafting behaviors [3] ; however, its predictive power was low to medium, and differed for distinct crafting behaviors. keywords: crafting; demands; efficacy; factor; jcse; job; model; resources; self; study cache: cord-314908-kp2jznwb.txt plain text: cord-314908-kp2jznwb.txt item: #336 of 449 id: cord-315149-71bmj5il author: Caballero Bermejo, Antonio F. title: Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial date: 2020-09-16 words: 11238 flesch: 40 summary: Also, it will stick to the recommendations given by the consensus documents of the scientific journals3,4 to improve reliability and value of medical research literature by promoting transparent and accurate reporting of clinical research studies. The Principal Investigator may decide to conduct final analysis of study data at any time, even while some subjects may remain in long-term follow-up. keywords: clinical; consent; covid-19; data; dose; failure; following; il6; intervention; investigator; patients; protocol; sarilumab; soc; sponsor; study; treatment; trial cache: cord-315149-71bmj5il.txt plain text: cord-315149-71bmj5il.txt item: #337 of 449 id: cord-316126-j51dik7f author: Zhang, X. Sophie title: SARS-CoV-2 and Health Care Worker Protection in Low-Risk Settings: a Review of Modes of Transmission and a Novel Airborne Model Involving Inhalable Particles date: 2020-10-28 words: 12443 flesch: 29 summary: Recently, the WHO has acknowledged that short-range aerosol transmission, particularly in specific indoor locations, such as crowded and inadequately ventilated spaces over a prolonged period of time with infected persons cannot be ruled out but specifies that the significance of COVID-19 airborne transmission has not been convincingly demonstrated and requires further research (1) . World Health Organization Evidence of airborne transmission of the severe acute respiratory syndrome virus Environmental transmission of SARS at Amoy Gardens Cluster of SARS among medical students exposed to single patient Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS) SARS among critical care nurses Intubation of SARS patients: infection and perspectives of healthcare workers Illness in intensive care staff after brief exposure to severe acute respiratory syndrome Lack of SARS transmission among healthcare workers, United States Lack of SARS transmission among public hospital workers SARS-CoV-2 in environmental samples of quarantined households Relative contributions of transmission routes for COVID-19 among healthcare personnel providing patient care Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care Investigating SARS-CoV-2 surface and air contamination in an acute healthcare setting during the peak of the COVID-19 pandemic in London Environmental and aerosolized SARS-CoV-2 among hospitalized COVID-19 patients 2020. keywords: aerosols; airborne; care; contact; control; coronavirus; cov-2; covid-19; hcws; health; health care; infection; masks; particles; patients; protection; respirators; review; risk; sars; settings; studies; transmission; workers cache: cord-316126-j51dik7f.txt plain text: cord-316126-j51dik7f.txt item: #338 of 449 id: cord-316666-qif1k62t author: Ghati, Nirmal title: Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial date: 2020-10-30 words: 4405 flesch: 39 summary: Patients with early discharge (due to clinical improvement and patient's preference for home isolation) will be followed up by alternate day telephonic contact till 10 th day of drug regimen. The safety of these drugs in COVID-19 patients will also be evaluated. keywords: aspirin; atorvastatin; covid-19; days; disease; group; infection; patients; statins; study; therapy; trial cache: cord-316666-qif1k62t.txt plain text: cord-316666-qif1k62t.txt item: #339 of 449 id: cord-316746-toen5nvr author: Alves, F. title: Canine parvovirus: a predicting canine model for sepsis date: 2020-06-15 words: 6207 flesch: 43 summary: The main objective of the current study was to assess the prognostic value of the presenting vital signs as well as to evaluate the possibility of stratifying and classifying septic animals according to a proposed PIRO classification system, using parvovirus infection as a natural model for sepsis study [10] . This methodology could help to assess prognosis and be part of the clinical decision making, as well as helping in the enrolment of study populations in future sepsis studies. keywords: criteria; dogs; dysfunction; infection; organ; outcome; piro; response; sepsis; sirs; study cache: cord-316746-toen5nvr.txt plain text: cord-316746-toen5nvr.txt item: #340 of 449 id: cord-317344-wznzmssz author: Iannitti, T. title: Therapeutical use of probiotic formulations in clinical practice date: 2010-06-23 words: 24555 flesch: 38 summary: The study showed the following results: one hundred subjects completed the study (48 in the probiotic combination group and 52 in the placebo group); the probiotic combination was not superior to the placebo in relieving symptoms of IBS (42.6% versus 42.3% improvement); the decrease of abdominal pain between the first and the fourth week of treatment was significantly higher in probiotic treated patients (À41.9 versus À24.2%, P ¼ 0.048). Sixty six patients (88%) were symptom-free after the 24th month of treatment: 11 of group M1, 8 of group M2, 15 of group LM1, 12 of group LM2 and 20 in group L. Four patients (5.33%) suspended the treatment during the follow-up: all experienced recurrence of symptoms (100%), and two of them developed diverticulitis (50%). keywords: activity; administration; authors; bacteria; bowel; cells; colon; daily; day; days; diarrhea; disease; effect; et al; group; ibs; lactobacillus; microbiota; p ¼; pain; patients; placebo; placebo group; probiotic; pylori; rhamnosus; strains; study; symptoms; therapy; treatment; trial; use; weeks cache: cord-317344-wznzmssz.txt plain text: cord-317344-wznzmssz.txt item: #341 of 449 id: cord-318063-bainw3d6 author: Haque, Mainul title: Health care-associated infections – an overview date: 2018-11-15 words: 8259 flesch: 37 summary: in Intensive Care Unit of a Tertiary Care Hospital Surveillance and Prevention of healthcare associated infections Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections The clinical and economic consequences of nosocomial central venous catheter-related infection: are antimicrobial catheters useful? Department of Health & Human Services Central line-associated blood stream infections: characteristics and risk factors for mortality over a 5.5-year period Central line-associated bloodstream infections among critically-ill patients in the era of bundle care Central line-associated bloodstream infection in hospitalized children with peripherally inserted central venous catheters: extending risk analyses outside the intensive care unit Surgical Site Infections Centers for Disease Control and Prevention. Reduction in the Prevalence of Healthcare-Associated Infections in U. S. Acute Care Hospitals Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Survey Burden of Six Healthcare-Associated Infections on European Population Health: Estimating Incidence-Based Disability-Adjusted Life Years through a Population Prevalence-Based Modelling Study Prevalence, incidence burden, and clinical impact of healthcare-associated infections and antimicrobial resistance: a national prevalent cohort study in acute care hospitals in Greece The Burden of Healthcare-Associated Infections in Southeast Asia: A Systematic Literature Review and Meta-analysis Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran Investigating potential sources of transmission of healthcare-associated infections in a regional hospital Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America National Healthcare Safety Network (NHSN) Team and Participating NHSN Facilities. keywords: care; catheter; control; hand; hcais; health; healthcare; hospital; hygiene; infections; patients; pneumonia; prevention; resistance; ssis; study; surgery; surgical cache: cord-318063-bainw3d6.txt plain text: cord-318063-bainw3d6.txt item: #342 of 449 id: cord-318092-errwp80i author: Ren, L. title: Assessment of Hydroxychloroquine and Chloroquine Safety Profiles: A Systematic Review and Meta-Analysis date: 2020-05-08 words: 5941 flesch: 52 summary: For age, we separated CQ trials into <30 years-old and ≥30 years-old, while we separated HCQ trials into <50 years-old and ≥50 years-old. For drug duration, we divided CQ studies into <1 week and ≥1 week, while we divided HCQ studies into <6 months and ≥6 months. keywords: aes; chloroquine; hcq; meta; placebo; preprint; studies; total; trials cache: cord-318092-errwp80i.txt plain text: cord-318092-errwp80i.txt item: #343 of 449 id: cord-318209-llucxztc author: Öztürk, Selçuk title: Therapeutic Applications of Stem Cells and Extracellular Vesicles in Emergency Care: Futuristic Perspectives date: 2020-08-24 words: 13636 flesch: 29 summary: A phase-1 clinical trial investigating autologous BM-derived mononuclear cell (BM-MNC) infusion in pediatric TBI patients indicated that Fig. 1 Main pathological conditions requiring acute emergency care that can benefit from stem cell therapies or extracellular vesicle therapies in the future harvesting and infusion of stem cells is safe in children with no infusion related toxicity or death A recently published systematic review of 76 studies testing stem cells in rodent ischemic stroke models and 4 randomized human clinical trials encompassing ischemic stroke patients treated with autologous stem cells with at least one year follow-up period demonstrated that stem cell therapies show beneficial effects in terms of behavior and histological outcomes in rodents. keywords: acute; cells; effects; evs; exosomes; extracellular; human; injury; mesenchymal; mscs; patients; potential; radiation; stem; stem cells; stroke; studies; study; therapies; therapy; tissue; treatment; vesicles cache: cord-318209-llucxztc.txt plain text: cord-318209-llucxztc.txt item: #344 of 449 id: cord-318342-eipscagh author: Chen, Juan title: The Impact of COVID-19 on Blood Glucose: A Systematic Review and Meta-Analysis date: 2020-10-05 words: 3603 flesch: 43 summary: This may be one of the reasons that increased blood glucose was observed in COVID-19 patients without a prior history of diabetes (4). It remains unclear regarding the effect of severity of COVID-19 infection on glycemic parameters, including blood glucose and glycated haemoglobinA1c (HbA1c). keywords: blood; covid-19; diabetes; glucose; infection; patients; studies cache: cord-318342-eipscagh.txt plain text: cord-318342-eipscagh.txt item: #345 of 449 id: cord-318753-ribybqfo author: Kwok, C. S. title: Influenza, influenza‐like symptoms and their association with cardiovascular risks: a systematic review and meta‐analysis of observational studies date: 2015-05-04 words: 4086 flesch: 35 summary: The most reliable diagnostic methodology is laboratory serological tests, as other chest infections or atypical respiratory infections may have clinical features consistent with influenza infection. However, even when serological tests were used to ascertain influenza infection, it is possible that patients who did not have serology positive influenza did not have flu and this may account for the dissimilarity between the two large cohorts evaluating public health records and the remaining studies. keywords: illness; infection; influenza; risk; studies; study; symptoms cache: cord-318753-ribybqfo.txt plain text: cord-318753-ribybqfo.txt item: #346 of 449 id: cord-319323-1qt7vf59 author: Chakraborty, Amartya title: Around the world in 60 days: an exploratory study of impact of COVID-19 on online global news sentiment date: 2020-10-21 words: 7876 flesch: 44 summary: Personal and Ubiquitous Computing Sentiment analysis and the complex natural language Stock price prediction using news sentiment analysis Sentiment analysis on english financial news Finenews fine-grained semantic sentiment analysis on financial microblogs and news Market trend prediction using sentiment analysis: lessons learned and paths forward Enhanced news sentiment analysis using deep learning methods Discovering the correlation between stock time series and financial news Time series analysis on stock market for text mining correlation of economy news Trading strategies to exploit blog and news sentiment Agenda-setting The agenda-setting function of mass media Problems and opportunities in agenda-setting research After disaster: Given these observations and the ongoing pandemic, the authors were motivated to make the following research contributions: -The current work determines the general sentiment of news articles during the ongoing pandemic with unsupervised and transfer learning-based approaches, -This is the only work, as per the authors' knowledge, that determines the implications of temporal statistics in a pandemic situation, on news sentiment throughout the world during a fixed period of study. keywords: analysis; cases; correlation; covid-19; data; deaths; global; negativity; news; news sentiment; number; sentiment; study cache: cord-319323-1qt7vf59.txt plain text: cord-319323-1qt7vf59.txt item: #347 of 449 id: cord-319504-jb455t9p author: Suess, Thorsten title: The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011 date: 2012-01-26 words: 6955 flesch: 46 summary: However, one subgroup-analysis (restricting intervention households to those where intervention started within 36 h of symptom onset) The reason for the high SAR of 25% in MH households from the 2010/11 season (with 35% the SAR was even higher when only households with Influenza-B positive index patients were considered) remains unclear. keywords: adherence; analysis; facemasks; group; hand; household; index; influenza; intervention; study cache: cord-319504-jb455t9p.txt plain text: cord-319504-jb455t9p.txt item: #348 of 449 id: cord-319642-ceur0n0b author: Hamdan Alshehri, Hanan title: Factors influencing the integration of a palliative approach in intensive care units: a systematic mixed-methods review date: 2020-07-22 words: 5714 flesch: 39 summary: key: cord-319642-ceur0n0b authors: Hamdan Alshehri, Hanan; Olausson, Sepideh; Öhlén, Joakim; Wolf, Axel title: Factors influencing the integration of a palliative approach in intensive care units: a systematic mixed-methods review date: 2020-07-22 journal: BMC Palliat Care DOI: 10.1186/s12904-020-00616-y sha: doc_id: 319642 cord_uid: ceur0n0b BACKGROUND: While a palliative approach is generally perceived to be an integral part of the intensive care unit (ICU), the provision of palliative care in this setting is challenging. Multiple electronic databases were used, and the following search terms were utilized: implementation, palliative care, and intensive care unit. keywords: approach; care; factors; family; icu; integration; intensive; palliative; patients; studies; study cache: cord-319642-ceur0n0b.txt plain text: cord-319642-ceur0n0b.txt item: #349 of 449 id: cord-320091-2lrqubdl author: Badawi, Alaa title: Prevalence of chronic comorbidities in dengue fever and West Nile virus: A systematic review and meta-analysis date: 2018-07-10 words: 8525 flesch: 44 summary: ORs of severe flavivirus diseases were about 2 to 4 in infected patients with comorbidities such as diabetes, hypertension and heart diseases. Currently, our knowledge of the host-related factors that influence the pathogenesis of severe disease is inadequate to allow prediction of who will develop severe clinical illness. keywords: cases; comorbidities; dengue; denv; diabetes; diseases; fever; flavivirus; infection; patients; prevalence; risk; studies; study; west; wnv cache: cord-320091-2lrqubdl.txt plain text: cord-320091-2lrqubdl.txt item: #350 of 449 id: cord-320172-qw47pf9r author: Greaves, Peter title: VII Digestive System 1 date: 2000-12-31 words: 47447 flesch: 33 summary: It has been suggested from studies of the effects of anticancer compounds on neoplastic colonic cells that intestinal cells may possess inherent protective properties in the form of an accelerated efflux pump which can serve to protect them from potentially damaging agents (Klohs and Steinkampf, 1986) . A histochemical study Role of intestinal metaplasia in the histogenesis of gastric carcinoma Colorectal mucin histochemistry in health and disease: A critical review Uptake of particulate and soluble antigens in the small intestines of the rat Chemical colitis due to endoscopic cleaning solutions: A mimic of pseudomembranous colitis Pathology of Domestic Animals Intestinal accumulation of urea in germ-free animals: A factor in caecal enlargement Digestive enzymes in the parotid and submandibular glands of mammals Morphologishe Veränderungen der Magenmukosa von Ratten nach chronischer Antazidagabe Enteric viruses of non human primates Increased accumulation of sulfated glycoaminoglycans in cultures of human fibroblasts from phenytoin-induced gingival overgrowth New insights into the stem cells and the precursors of gastric epithelium Colonic lymphoid-glandular complex (microbursa): Nature and morphology Lymphoid tissue and lymphoid-glandular complexes of the colon: Relation to diverticulosis Histology of salivary gland infarction in the dog Adrenergic factors involved in the control of crypt cell proliferation in jejunum and descending colon of mouse Pill esophagitis Immunogold localization of ingested kidney bean (Phaseolus vugaris) lectins in epithelial cells of the rat small intestine Epithelial dysplasia of the rabbit colon induced by degraded carrageenan Hyperkeratinization and hyperplasia of the forestomach epithelium in vitamin A deficient rats Intrinsic resistance of colon tumors to anthrapyrazoles and antracyclines may be linked with a detoxification mechanism of intestinal cells (Abstract No. 1040) keywords: acid; activity; administration; agents; animals; cells; changes; chronic; colon; colonic; crypt; damage; differences; disease; dogs; drugs; effects; epithelium; et al; factor; features; forestomach; form; gastric; gastric mucosa; gastrointestinal; glands; glandular; goblet cells; growth; high; human; hyperplasia; increase; inflammation; inflammatory; intestine; laboratory; lesions; lymphocytes; lymphoid; man; metaplasia; mice; mouse; mucins; mucosa; non; number; oral; presence; rats; result; rodents; salivary; secretion; species; stomach; studies; study; surface; tissue; tract; treatment; ulceration; ulcers cache: cord-320172-qw47pf9r.txt plain text: cord-320172-qw47pf9r.txt item: #351 of 449 id: cord-320828-5ksho1bh author: Narchi, Hassib title: Nasopharyngeal Isolates from a Cohort of Medical Students with or without Pharyngitis date: 2020-10-05 words: 3400 flesch: 50 summary: A Centor score of ≤2 is the suggested cut-off value for the treatment of S. pyogenes pharyngitis. These findings confirm observations from previous reports and suggests that the specificity and sensitivity of this cut-off score for S. pyogenes pharyngitis may be much lower in other populations. keywords: centor; pharyngitis; pyogenes; score; students; study cache: cord-320828-5ksho1bh.txt plain text: cord-320828-5ksho1bh.txt item: #352 of 449 id: cord-320851-zhf8jdcl author: Patil, Satish title: Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts date: 2015-11-24 words: 7696 flesch: 48 summary: 60 Because prodrugs only release milligram amounts of formaldehyde from phosphonooxymethyl prodrugs per day, the small amount of formaldehyde adds very little to the baseline exposure of gram quantities produced by normal metabolism. Role of epoxides in binding and activity The main anticancer bullets of the Chinese medicinal herb, Thunder God Vine Triptolide induces the expression of miR-142−3p: A negative regulator of Heat Shock Protein 70 and pancreatic cancer cell proliferation Role of Hsp-70 in triptolide-mediated cell death of neuroblastoma Triptolide directly inhibits dCTP pyrophosphatase Triptolide: Structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease A potential male contraceptive Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD Preclinical antileukemic activity, toxicology, toxicokinetics and formulation development of triptolide derivative MRx102 Design, synthesis and structure−activity relationships studies on the D ring of the natural product triptolide Total synthesis of novel D-ring-modified triptolide analogues: structure-cytotoxic activity relationship studies on the D-ring of triptolide A phase I study of ethyl acetate extract of the Chinese antirheumatic herb Tripterygium wilfordii Hook F in rheumatoid arthritis Benefit of an extract of Tripterygium wilfordii Hook F in patients with rheumatoid arthritis -A double-blind, placebo-controlled study Preparation of triptolide prodrugs having high aqueous solubility Synthesis of triptolide prodrugs having high aqueous solubility for immunosuppressive and anti-inflammatory treatment PG490−88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy Phase I dose-escalation study of F60008, a novel apoptosis inducer, in patients with advanced solid tumors Rationale for design of biologically reversible drug derivatives: Prodrugs Fosamprenavir -A novel protease inhibitor and prodrug of amprenavir A case for prodrugs: keywords: cancer; cell; chemical; phosphate; prodrugs; solubility; solution; stability; study; synthesis; triptolide; tumor; vivo; water cache: cord-320851-zhf8jdcl.txt plain text: cord-320851-zhf8jdcl.txt item: #353 of 449 id: cord-320931-2ycf6qd8 author: Harnett, Joanna title: The effects of Sambucus nigra berry on acute respiratory viral infections: a rapid review of clinical studies date: 2020-08-22 words: 1772 flesch: 44 summary: Findings from included studies suggest that mono-herbal preparations of S.nigra berry (in extract or lozenge formulation) may reduce influenza-type symptoms, including fever, headache, nasal congestion and nasal mucous discharge in adults, when taken within the first 48 hours of symptom onset. Pharmacognosy magazine Chapter 8: Assessing risk of bias in included studies. keywords: berry; bias; risk; s.nigra; studies cache: cord-320931-2ycf6qd8.txt plain text: cord-320931-2ycf6qd8.txt item: #354 of 449 id: cord-320976-y47p1c15 author: Madhwal, Sandeep title: Ambient bioaerosol distribution and associated health risks at a high traffic density junction at Dehradun city, India date: 2020-02-22 words: 6039 flesch: 38 summary: Statistical analysis was conducted to evaluate the relationship between bioaerosol concentration, vehicular count, PM concentration, and meteorological parameters. The formula used for calculating bioaerosol concentration is as follows: keywords: bacteria; bioaerosol; concentration; distribution; fungal; fungi; sampling; size; study cache: cord-320976-y47p1c15.txt plain text: cord-320976-y47p1c15.txt item: #355 of 449 id: cord-321697-yua3apfi author: Crigna, Adriana Torres title: Cell-free nucleic acid patterns in disease prediction and monitoring—hype or hope? date: 2020-10-29 words: 10912 flesch: 32 summary: In breast tumour studies, many differentially expressed miRNA have been detected in breast cancer patients compared with healthy women. Additionally, 4 upregulated plasma miRNA (miR-148b, miR-376c, miR-409-3p and miR-801) managed to discriminate breast cancer patients from controls [166] . keywords: analysis; biomarkers; blood; breast; cancer; cell; cfdna; crc; detection; diabetes; disease; dna; levels; lung; mirna; patients; patterns; plasma; potential; prostate; serum; stress; study; tumour cache: cord-321697-yua3apfi.txt plain text: cord-321697-yua3apfi.txt item: #356 of 449 id: cord-321827-e7zc44ca author: Halter, Mary title: The determinants and consequences of adult nursing staff turnover: a systematic review of systematic reviews date: 2017-12-15 words: 8775 flesch: 38 summary: Review design I (for all stages of the overview): any form of literature review (e.g. either systematic or non-systematic reviews) which had been peer-reviewed, contained a statement of review, reported its search strategy and/or inclusion/exclusion criteria, reported either empirical findings or a list of included primary studies and included a methodological quality assessment of its included primary studies. Exclusion criteria were as follows: Reports from any types of primary studies; reviews published in language other than English; reviews that did not evaluate adult nursing turnover as described in the inclusion criteria or presented data on nurses working across settings that could include the care of children or in specific mental health settings; reviews that did not report empirical findings; reviews published only in abstract form; any form of literature review using informal and subjective methods to collect and interpret evidence, commentaries and non peer-reviewed reviews; any review in which majority of included articles were non-peer reviewed publications and reviews that did not report an appraisal of the quality of the studies they included. keywords: consequences; determinants; evidence; health; intention; literature; nurses; nursing; quality; research; reviews; studies; study; turnover cache: cord-321827-e7zc44ca.txt plain text: cord-321827-e7zc44ca.txt item: #357 of 449 id: cord-321836-rbqqgekw author: Everest, T. title: Determination of agricultural land suitability with a multiple-criteria decision-making method in Northwestern Turkey date: 2020-08-06 words: 7476 flesch: 52 summary: Land suitability studies started at the beginning of the twentieth century with hand-drawn overlay analysis (Steinitz 1976; Collins et al. 2001; Malczewski 2004) . key: cord-321836-rbqqgekw authors: Everest, T.; Sungur, A.; Özcan, H. title: Determination of agricultural land suitability with a multiple-criteria decision-making method in Northwestern Turkey date: 2020-08-06 journal: keywords: agriculture; analysis; area; criteria; data; depth; erosion; gis; land; land suitability; points; slope; soil; study; suitability; use cache: cord-321836-rbqqgekw.txt plain text: cord-321836-rbqqgekw.txt item: #358 of 449 id: cord-323463-osf6t7cw author: Cercenado, Emilia title: Update on bacterial pathogens: virulence and resistance date: 2008-04-30 words: 15034 flesch: 38 summary: CA-MRSA infections refer to MRSA infections in patients lacking established MRSA risk factors and without a previous history of MRSA infection or colonization: they do not have a medical history in the past year of hospitalization, healthcare-related admission (to a nursing home, skilled nursing facility or hospice), dialysis, surgery, or implantation of a permanent indwelling catheter or other medical devices 8, 14 . However, there is now an increasing number of reports of MRSA infections in the community that have not escaped from the hospitals, and no longer can MRSA be considered as an exclusively nosocomial pathogen. keywords: aureus; authors; cases; children; community; control; disease; hospital; incidence; infections; isolates; mrsa; patients; pertussis; resistance; samples; staphylococcus; strains; study; treatment; use; vaccination; vaccine; vancomycin cache: cord-323463-osf6t7cw.txt plain text: cord-323463-osf6t7cw.txt item: #359 of 449 id: cord-323910-lms3xw4k author: Putman, Michael title: Antirheumatic Disease Therapies for the Treatment of COVID‐19: A Systematic Review and Meta‐analysis date: 2020-08-02 words: 4594 flesch: 38 summary: Included studies described one or more relevant clinical outcomes in five or more people who were infected with SARS‐CoV‐2 and were treated with antirheumatic disease therapy between 01/01/2019 and 05/29/2020. Infectious Diseases (except HIV/AIDS) Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care keywords: bias; cohort; covid-19; disease; hydroxychloroquine; mortality; patients; risk; studies; study cache: cord-323910-lms3xw4k.txt plain text: cord-323910-lms3xw4k.txt item: #360 of 449 id: cord-324006-y4bd38zz author: Rishu, Asgar H. title: Time required to initiate outbreak and pandemic observational research()() date: 2017-03-01 words: 2773 flesch: 34 summary: For debate: should observational clinical studies require ethics committee approval? Should observational clinical studies require ethics committee approval? keywords: data; days; reb; research; sharing; study; time cache: cord-324006-y4bd38zz.txt plain text: cord-324006-y4bd38zz.txt item: #361 of 449 id: cord-324453-gei7os7s author: Hura, Nanki title: Treatment of post‐viral olfactory dysfunction: an evidence‐based review with recommendations date: 2020-06-25 words: 5235 flesch: 41 summary: The remaining 3 studies were all level 4 evidence with no control groups, with the largest cohort of PVOD patients (n = 244) studied by Mori et al. 28 Specific comparative analyses for PVOD patients in each treatment group could not be fully captured, though thresholds became measurable in 13 anosmic patients after caroverine treatment, of which 6 (46%) had PVOD. keywords: evidence; level; olfactory; patients; pvod; studies; study; training; treatment cache: cord-324453-gei7os7s.txt plain text: cord-324453-gei7os7s.txt item: #362 of 449 id: cord-324635-27q3nxte author: Bouza, Emilio title: The situation of infection in the elderly in Spain: a multidisciplinary opinion document date: 2020-09-08 words: 15951 flesch: 42 summary: In a study conducted in China, in 6 sentinel hospitals, it was observed that 31.64% of elderly patients with respiratory infection had a viral aetiology (41.8% among extra-hospital infections and 25.7% among fecting the elderly vary depending on the clinical environment (home, nursing home, hospital) and the functional status of the patient. It is interesting to note the safety of using the same therapeutic options in elderly patients, including faecal microbiota transplantation [29, 30] . keywords: age; care; cases; community; control; data; diseases; emergency; health; healthcare; homes; hospital; infections; information; life; nursing; patients; people; pneumonia; population; prevalence; prevention; problems; spain; spanish; study; term; tract; treatment; use; years cache: cord-324635-27q3nxte.txt plain text: cord-324635-27q3nxte.txt item: #363 of 449 id: cord-324786-8k81jetq author: Chang, Anne B title: Antibiotics for bronchiectasis exacerbations in children: rationale and study protocol for a randomised placebo-controlled trial date: 2012-08-31 words: 5675 flesch: 38 summary: key: cord-324786-8k81jetq authors: Chang, Anne B; Grimwood, Keith; Robertson, Colin F; Wilson, Andrew C; van Asperen, Peter P; O’Grady, Kerry-Ann F; Sloots, Theo P; Torzillo, Paul J; Bailey, Emily J; McCallum, Gabrielle B; Masters, Ian B; Byrnes, Catherine A; Chatfield, Mark D; Buntain, Helen M; Mackay, Ian M; Morris, Peter S title: Antibiotics for bronchiectasis exacerbations in children: rationale and study protocol for a randomised placebo-controlled trial date: 2012-08-31 journal: Trials DOI: 10.1186/1745-6215-13-156 sha: doc_id: 324786 cord_uid: 8k81jetq BACKGROUND: Despite bronchiectasis being increasingly recognised as an important cause of chronic respiratory morbidity in both indigenous and non-indigenous settings globally, high quality evidence to inform management is scarce. Indeed, no published RCTs addressing the treatment of bronchiectasis exacerbations in children exist. keywords: acid; antibiotic; azithromycin; bronchiectasis; children; clavulanic; cough; data; day; exacerbations; lung; non; placebo; study cache: cord-324786-8k81jetq.txt plain text: cord-324786-8k81jetq.txt item: #364 of 449 id: cord-324859-0yuhb5dl author: Mulchandani, Rubina title: Deciphering the COVID‐19 cytokine storm: Systematic review and meta‐analysis date: 2020-11-02 words: 6722 flesch: 39 summary: Well‐designed and adequately powered prospective studies are needed to amplify the current evidence and provide definitive answers to dilemmas regarding timing and type of anti‐COVID‐19 therapy particularly in severe patients. 58 53% M Not given 13 55 The number of T cells and CD8 + T cells was significantly lower in severe patients than that in the mild cases. keywords: analysis; coronavirus; covid-19; cytokine; disease; il-6; inflammatory; levels; meta; patients; studies; study cache: cord-324859-0yuhb5dl.txt plain text: cord-324859-0yuhb5dl.txt item: #365 of 449 id: cord-324981-teywszlm author: Eccles, Ron title: Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold date: 2010-08-10 words: 5475 flesch: 49 summary: This result indicates that the treatment of patients with Iota Carrageenan nasal spray leads to a highly statistically significant reduction of viral load in the nasal cavity, while placebo treatment has no influence on viral replication at all. Subjects completed a daily diary of common cold symptom scores over 7 days and underwent nasal lavage on day 1 before the first treatment and on days 3 or 4. keywords: carrageenan; cold; days; iota; nasal; nose; patients; placebo; spray; study; symptoms; treatment cache: cord-324981-teywszlm.txt plain text: cord-324981-teywszlm.txt item: #366 of 449 id: cord-325201-yoy7kdli author: Timsit, Jean-François title: Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics date: 2015-03-26 words: 9133 flesch: 38 summary: Under this context, recent studies shed more light on the aminoglycoside PK/PD properties in ICU patients. Energy deficit in ICU patients is mainly caused by reduced intake due to under-prescribed calories and frequent feeding interruptions. keywords: candida; care; colonization; escalation; icu; infections; intensive; mortality; patients; pneumonia; sepsis; shock; study; therapy; treatment; use cache: cord-325201-yoy7kdli.txt plain text: cord-325201-yoy7kdli.txt item: #367 of 449 id: cord-325512-eehp4uh9 author: Li, Yiwei title: Coronavirus disease 2019 (COVID-19) related cytopenia: A protocol for systematic review and meta-analysis date: 2020-09-04 words: 2070 flesch: 40 summary: In addition, gray literatures will also be searched, including conference proceedings and reference lists of included studies. Recent papers pointed out the cytopenia in COVID-19 patients including lymphopenia, neutrophilia, thrombocytopenia and lower level of hemoglobin had prognostic significance. keywords: analysis; covid-19; meta; patients; studies; study cache: cord-325512-eehp4uh9.txt plain text: cord-325512-eehp4uh9.txt item: #368 of 449 id: cord-326004-wg47sd06 author: Wilson, Patrick T title: Respiratory Pathogens in Children 1 Month to 5 Years of Age Presenting With Undifferentiated Acute Respiratory Distress in 2 District-Level Hospitals in Ghana date: 2018-09-03 words: 2196 flesch: 43 summary: key: cord-326004-wg47sd06 authors: Wilson, Patrick T; Baiden, Frank; Brooks, Joshua C; Giessler, Katie M; Apio, Gavin; Punguyire, Damien; Moresky, Rachel T; Sylverken, Justice; Nyarko-Jectey, Kwadwo; Tagbor, Harry; LaRussa, Philip S title: Respiratory Pathogens in Children 1 Month to 5 Years of Age Presenting With Undifferentiated Acute Respiratory Distress in 2 District-Level Hospitals in Ghana date: 2018-09-03 journal: J Pediatric Infect Dis Soc DOI: 10.1093/jpids/piy090 sha: doc_id: 326004 cord_uid: wg47sd06 Ghanaian children (2176) aged <5 years who presented with undifferentiated acute respiratory distress were tested for respiratory pathogens using a BioFire FilmArray polymerase chain reaction assay. Ghanaian children (2176) aged <5 years who presented with undifferentiated acute respiratory distress were tested for respiratory pathogens using a BioFire FilmArray polymerase chain reaction assay. keywords: children; pathogens; season; specimens; study; virus; years cache: cord-326004-wg47sd06.txt plain text: cord-326004-wg47sd06.txt item: #369 of 449 id: cord-326785-le2t1l8g author: None title: Pathological Society of Great Britain and Ireland. 163rd meeting, 3–5 July 1991 date: 2005-06-15 words: 22778 flesch: 36 summary: SSCs in the Connective tissue were Melled with the antibody along With a number of other cells (lymphocytes) within the germinal centres. These results show that sadium iodoacetate reduces cell number and interferes wqth the manufacture of matrix components. keywords: acp; adhesion; age; analysis; antibodies; antibody; antigen; areas; associated; benign; biopsies; biopsy; bone; breast; carcinoma; cases; cells; changes; chronic; common; day; days; diagnosis; disease; distribution; dna; electron; epithelium; evidence; expression; features; formation; gene; grade; group; high; hpv; human; increase; inflammatory; kidney; lesions; light; lor; low; lung; malignant; material; mean; microscopy; model; muscle; negative; non; normal; number; paraffin; pathology; patients; present; protein; range; renal; response; results; sections; specimens; staining; study; system; technique; thought; time; tissue; treatment; tumour; turnours; type; wlth; years cache: cord-326785-le2t1l8g.txt plain text: cord-326785-le2t1l8g.txt item: #370 of 449 id: cord-327460-wvd8hnfi author: van der Watt, A. S. J. title: Distant mood monitoring for depressive and bipolar disorders: a systematic review date: 2020-07-22 words: 5680 flesch: 42 summary: Distant mood monitoring was effective in improving depression scores but not mania scores. As a task-shifting intervention, distant mood monitoring may help to alleviate the burden on mental health providers in developing countries. keywords: depression; disorder; health; intervention; monitoring; mood; participants; review; studies; study cache: cord-327460-wvd8hnfi.txt plain text: cord-327460-wvd8hnfi.txt item: #371 of 449 id: cord-327607-g0jtrwot author: Weinberg, Marc Scott title: Clinical Trials and Tribulations in the COVID-19 Era date: 2020-05-19 words: 4316 flesch: 31 summary: This creates a dual challenge, as not only do study partners assist with coordinating visits, but one of their primary roles in several clinical studies is study partner assessment; study partners, who contribute significantly to behavioral and cognitive assessments during visits, are intended to have contact with the subject a minimum of two days per week, which is less of a problem when the partner is a spouse or lives in the home with the subject. As there are currently no FDA-approved disease-modifying therapies for Alzheimer's disease, volunteers participating in clinical trials for a potential disease-modifying drug often endorse the same goal: Let me do everything in my power to take back control of this disease or help others who come after me. keywords: alzheimer; assessment; covid-19; disease; person; research; safety; study; subjects; trials; visits cache: cord-327607-g0jtrwot.txt plain text: cord-327607-g0jtrwot.txt item: #372 of 449 id: cord-327967-cuy254tf author: Pierce John, P. title: Real-world exposure to graphic warning labels on cigarette packages in US smokers: The CASA randomized trial protocol date: 2020-09-20 words: 7314 flesch: 48 summary: Using information on brands purchased prior to randomization, the study purchased cigarette packs and repackaged cigarettes into study packs manufactured specifically for the GWL and Blank Pack study groups. Contemp Clin Trials DOI: 10.1016/j.cct.2020.106152 sha: doc_id: 327967 cord_uid: cuy254tf Background The US lags behind >120 countries in implementing graphic warning labels (GWLs) on cigarette packs. keywords: behavior; cigarette; data; gwl; gwls; intervention; month; pack; participants; smokers; smoking; study; tobacco; visit cache: cord-327967-cuy254tf.txt plain text: cord-327967-cuy254tf.txt item: #373 of 449 id: cord-328056-y5x80tuw author: Popescu, Corneliu P. title: Hydroxychloroquine-azithromycin for COVID-19 – Warranted or dangerous? date: 2020-05-30 words: 1125 flesch: 43 summary: This was appropriate for the research methods and for patient safety, but this might have removed patients from consideration who would have had unfavorable outcomes (and, thus, increased the mortality rates toward levels comparable to other studies). However, data from other studies raise a cry for caution, especially if considering giving this treatment to individuals who might have an underlying arrhythmia. keywords: hydroxychloroquine; patients; study cache: cord-328056-y5x80tuw.txt plain text: cord-328056-y5x80tuw.txt item: #374 of 449 id: cord-328720-o9h1vquo author: Davis, Cristina E. title: Breath analysis for respiratory infections date: 2020-09-18 words: 5835 flesch: 40 summary: Parallel animal model studies have provided insight into human breath biomarker studies. TB is one of the respiratory diseases for which breath analysis studies have been performed in both humans and animal models. keywords: analysis; biomarkers; breath; disease; fungal; human; infection; influenza; patients; samples; studies; study; virus cache: cord-328720-o9h1vquo.txt plain text: cord-328720-o9h1vquo.txt item: #375 of 449 id: cord-328979-xfze12ah author: Monto, Arnold S title: Data resource profile: Household Influenza Vaccine Evaluation (HIVE) Study date: 2019-04-30 words: 3879 flesch: 37 summary: The testnegative design: validity, accuracy and precision of vaccine efficacy estimates compared to the gold standard of randomised placebocontrolled clinical trials The case testnegative design for studies of the effectiveness of influenza vaccine The test-negative design for estimating influenza vaccine effectiveness Theoretical basis of the test-negative study design for assessment of influenza vaccine effectiveness An optimized enzymelinked lectin assay to measure influenza A virus neuraminidase inhibition antibody titers in human sera Influenza vaccine effectiveness in the community and the household Influenza vaccine effectiveness in households with children during the 2012-2013 season: assessments of prior vaccination and serologic susceptibility Substantial influenza vaccine effectiveness in households with children during the 2013-2014 influenza season, when 2009 pandemic influenza A(H1N1) virus predominated The household influenza vaccine effectiveness study: lack of antibody response and protection following receipt of 2014-2015 influenza vaccine Effectiveness of seasonal influenza vaccines in the United States during a season with circulation of all three vaccine strains Influenza vaccine effectiveness in the 2011-2012 season: protection against each circulating virus and the effect of prior vaccination on estimates Influenza vaccine effectiveness in the United States during 2012-2013: variable protection by age and virus type Influenza vaccine effectiveness against 2009 pandemic influenza A(H1N1) virus differed by vaccine type during 2013-2014 in the United States influenza vaccine effectiveness in the United States by vaccine type Influenza vaccine effectiveness in the United States during the 2015-2016 season The doctrine of original antigenic sin: separating good from evil Assessment of inactivated influenza-A vaccine after three outbreaks of influenza A at Christ's Hospital Efficacy of repeated annual immunization with inactivated influenza virus vaccines over a five year period Variable efficacy of repeated annual influenza vaccination Antibodies against the current influenza A(H1N1) vaccine strain do not protect some individuals from infection with contemporary circulating influenza A(H1N1) virus strains Influenza transmission in a cohort of households with children Stochastic processes constrain the within and between host evolution of influenza virus Application of an individual-based transmission hazard model for estimation of influenza vaccine effectiveness in a household cohort Co-colonization by Streptococcus pneumoniae and Staphylococcus aureus in the throat during acute respiratory illnesses Frequency of acute respiratory illnesses and circulation of respiratory viruses in households with children over 3 surveillance seasons The original aims of this study were to estimate influenza vaccine effectiveness annually and to compare those estimates with those from TND studies conducted in outpatient clinics during the same seasons. keywords: effectiveness; illness; influenza; season; specimens; study; vaccination; vaccine; viruses cache: cord-328979-xfze12ah.txt plain text: cord-328979-xfze12ah.txt item: #376 of 449 id: cord-329313-tlbjw5kn author: Crilly, Philip title: A Systematic Review of Randomized Controlled Trials of Telehealth and Digital Technology Use by Community Pharmacists to Improve Public Health date: 2020-08-04 words: 6512 flesch: 48 summary: Although, currently, the focus for community pharmacy is to deal with the pandemic, there may come a time, in the near future, when the pressures of this subside, and then community pharmacists will need to consider how they continue to deliver public health interventions that deliver positive health outcomes, but in an era of continued social distancing [3] . MeSH terms and KWs for public health interventions and outcomes included public health (MeSH), smoking cessation (MeSH), weight-loss (MeSH), health (MeSH), sexual health (MeSH), and alcohol brief intervention (KW). keywords: adherence; community; health; intervention; medication; pharmacist; pharmacy; public; studies; study; use cache: cord-329313-tlbjw5kn.txt plain text: cord-329313-tlbjw5kn.txt item: #377 of 449 id: cord-329344-06uk5sjp author: Neumann-Podczaska, Agnieszka title: COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review date: 2020-07-23 words: 5928 flesch: 40 summary: Description: Ground Glass Opacities (GGO) was the most commonly reported observation in radiological imaging of older COVID-19 patients. 10-18, 24-26, 28 Besides a risk for secondary infection or ARDS, older COVID-19 patients are prone to renal injury over the course of the disease. keywords: clinical; covid-19; data; disease; findings; patients; population; review; studies; study cache: cord-329344-06uk5sjp.txt plain text: cord-329344-06uk5sjp.txt item: #378 of 449 id: cord-329723-74bhv8cr author: Debes, Jose D. title: COVID-19 and the liver: the perils of non-peer reviewed science in times of a pandemic date: 2020-04-10 words: 323 flesch: 34 summary: However, when such studies involve data related to single cell RNA sequencing, particularly in hepatocytes which has been shown to be particularly difficult to isolate and sequence, the reader is blind to the details of the study and directly susceptible to the conclusions of the authors. key: cord-329723-74bhv8cr authors: Debes, Jose D. title: COVID-19 and the liver: the perils of non-peer reviewed science in times of a pandemic date: 2020-04-10 journal: Gastroenterology DOI: 10.1053/j.gastro.2020.04.007 sha: doc_id: 329723 cord_uid: 74bhv8cr nan receptor referencing a manuscript that involves single cell RNA sequencing performed on liver cells. keywords: study cache: cord-329723-74bhv8cr.txt plain text: cord-329723-74bhv8cr.txt item: #379 of 449 id: cord-329999-flzqm3wh author: Buchanan, Tom title: Why do people spread false information online? The effects of message and viewer characteristics on self-reported likelihood of sharing social media disinformation date: 2020-10-07 words: 13823 flesch: 47 summary: Social media disinformation is very widely used as a tool of influence: computational propaganda has been described as a pervasive and ubiquitous part of modern everyday life [8] . Having shared material known to be untrue at the time (Table 6 ) was significantly predicted by lower Agreeableness and lower age. keywords: analysis; disinformation; facebook; likelihood; literacy; material; media; participants; people; sharing; stories; studies; study cache: cord-329999-flzqm3wh.txt plain text: cord-329999-flzqm3wh.txt item: #380 of 449 id: cord-330573-rr2r8245 author: Stockmann, Helena title: CytoResc – “CytoSorb” Rescue for critically ill patients undergoing the COVID-19 Cytokine Storm: A structured summary of a study protocol for a randomized controlled trial date: 2020-06-26 words: 1703 flesch: 48 summary: Approximately 8 - 10 % of COVID-19 patients present with a serious clinical course and need for hospitalization, 8% of hospitalized patients need ICU-treatment. However, in a number of patients a severe hyperinflammatory response with excessively elevated proinflammatory cytokines causes vasoplegic shock resistant to vasopressor therapy. keywords: cytosorb; patients; protocol; study; trial cache: cord-330573-rr2r8245.txt plain text: cord-330573-rr2r8245.txt item: #381 of 449 id: cord-330831-3b7vfv9b author: Hao, Fengyi title: A quantitative and qualitative study on the neuropsychiatric sequelae of acutely ill COVID-19 inpatients in isolation facilities date: 2020-10-19 words: 8243 flesch: 41 summary: A greater proportion of COVID-19 patients experienced impulsivity (p = 0.016) and insomnia (p = 0.039) than psychiatric patients and healthy controls. COVID-19 patients reported a higher psychological impact of the outbreak than psychiatric patients and healthy controls, with half of them having clinically significant symptoms of posttraumatic stress disorder. keywords: anxiety; covid-19; covid-19 patients; depression; health; impact; infection; isolation; outbreak; pandemic; patients; stress; study; symptoms cache: cord-330831-3b7vfv9b.txt plain text: cord-330831-3b7vfv9b.txt item: #382 of 449 id: cord-330994-6nu7utu1 author: Abdelrheem, Doaa A. title: The inhibitory effect of some natural bioactive compounds against SARS-CoV-2 main protease: insights from molecular docking analysis and molecular dynamic simulation date: 2020-10-01 words: 5323 flesch: 39 summary: TPSA of studied compounds was noticed in the range of 25.87-153.50 Å and is well below the limit of 160 Å. It can be predicted that all studied bioactive compounds obeyed Lipinski's rule of five and are likely to be orally active except compounds 5 and 9 as shown in Table 6 . Rat Acute Toxicity LD50 of all studied compounds was found between 1.95 and 2.75 mol/kg. keywords: 6lu7; caulerpin; complex; compounds; cov-2; covid-19; docking; molecular; protease; protein; sars; simulation; study cache: cord-330994-6nu7utu1.txt plain text: cord-330994-6nu7utu1.txt item: #383 of 449 id: cord-331487-jh34klbg author: Sivapalan, Pradeesh title: Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial date: 2020-06-10 words: 6407 flesch: 42 summary: The length of hospitalisation is observed to be relatively long, 10-15 days (3) , which in itself is a problem as hospitals can quickly reach the maximum capacity for hospitalisation and the proportion of patients who become critically ill have, based on the observations reported so far, had a mortality rate of> 60% (4), and overall mortality for admitted patients in China with COVID-19 infection is apparently unusually high for viral respiratory tract infections with an estimate of 25% (2). Annual monitoring after 5 years of treatment is recommended, however in risk patients initially annual control, see also Chloroquine derivatives (inflammatory rheumatic diseases), side effects. keywords: azithromycin; consent; covid-19; data; days; group; hydroxychloroquine; information; intervention; medication; patients; project; study; treatment; trial cache: cord-331487-jh34klbg.txt plain text: cord-331487-jh34klbg.txt item: #384 of 449 id: cord-331675-ipryt7o7 author: Itzchakov, Guy title: Can high quality listening predict lower speakers' prejudiced attitudes?() date: 2020-08-06 words: 11823 flesch: 40 summary: key: cord-331675-ipryt7o7 authors: Itzchakov, Guy; Weinstein, Netta; Legate, Nicole; Amar, Moty title: Can high quality listening predict lower speakers' prejudiced attitudes?() date: 2020-08-06 journal: J Exp Soc Psychol DOI: 10.1016/j.jesp.2020.104022 sha: doc_id: 331675 cord_uid: ipryt7o7 Theorizing from humanistic and motivational literatures suggests attitude change may occur because high quality listening facilitates the insight needed to explore and integrate potentially threatening information relevant to the self. keywords: attitudes; bias; change; conversation; effect; insight; listening; openness; participants; prejudice; quality listening; self; study cache: cord-331675-ipryt7o7.txt plain text: cord-331675-ipryt7o7.txt item: #385 of 449 id: cord-332559-2r2gavbq author: Kajdy, Anna title: Risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic: A web-based cross-sectional survey date: 2020-07-24 words: 5211 flesch: 46 summary: key: cord-332559-2r2gavbq authors: Kajdy, Anna; Feduniw, Stepan; Ajdacka, Urszula; Modzelewski, Jan; Baranowska, Barbara; Sys, Dorota; Pokropek, Artur; Pawlicka, Paulina; Kaźmierczak, Maria; Rabijewski, Michał; Jasiak, Hanna; Lewandowska, Roksana; Borowski, Dariusz; Kwiatkowski, Sebastian; Poon, Liona C. title: Risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic: A web-based cross-sectional survey date: 2020-07-24 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021279 sha: doc_id: 332559 cord_uid: 2r2gavbq INTRODUCTION: The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the coronavirus disease 19 (COVID-19) pandemic. keywords: anxiety; covid-19; data; depression; health; pandemic; pregnancy; questions; study; survey; women cache: cord-332559-2r2gavbq.txt plain text: cord-332559-2r2gavbq.txt item: #386 of 449 id: cord-333340-ekok0mp5 author: Graf, Erin H. title: Appropriate Use and Future Directions of Molecular Diagnostic Testing date: 2020-02-06 words: 5779 flesch: 24 summary: Another randomized controlled trial found no difference in length of stay or antibiotic usage, including duration, comparing adult patients who received syndromic panel testing with those who received conventional microbiologic testing [16] . However, retrospective analyses have the benefit of knowing the final diagnosis while at the time of clinical presentation, it may have been appropriate to order syndromic panel testing [43] . keywords: care; clinical; detection; impact; molecular; panel; patients; sequencing; stewardship; studies; testing; time cache: cord-333340-ekok0mp5.txt plain text: cord-333340-ekok0mp5.txt item: #387 of 449 id: cord-333801-4pjdutgg author: Awaisu, Ahmed title: Research Designs and Methodologies Related to Pharmacy Practice date: 2019-12-31 words: 8760 flesch: 31 summary: Narrative interviewing Exclusive and combined use of statins and aspirin and the risk of pancreatic cancer: a case-control study Pharmacists' involvement in and attitudes toward pharmacy practice research: a systematic review of the literature The contribution of case study research to knowledge of how to improve quality of care Perceptions of pharmacy faculty need for development in educational research The need for pharmacy practice research Spironolactone for nonresolving central serous chorioretinopathy: a Randomized Controlled Crossover Study Using thematic analysis in psychology The stepped wedge trial design: a systematic review Thematic analysis of qualitative research data: is it as easy as it sounds? Pharmacy practice research The Canadian Pharmacists Association defines pharmacy practice research as a component of health services research that focuses on the assessment and evaluation of pharmacy practice (Koshman and Blais, 2011) . keywords: case; cohort; control; data; design; et al; group; methods; pharmacy; pharmacy practice; practice; research; studies; study cache: cord-333801-4pjdutgg.txt plain text: cord-333801-4pjdutgg.txt item: #388 of 449 id: cord-334180-aqw9snt7 author: Doll, Julian title: Contrast-enhanced ultrasound for determining muscular perfusion after oral intake of L-citrulline, L-arginine, and galloylated epicatechines: A study protocol date: 2020-10-09 words: 4968 flesch: 40 summary: CEUS evaluates tissue microcirculation and appears to be a promising, non-invasive technique in the assessment of muscle perfusion. The safety of Sonovue ® in abdominal applications: retrospective analysis of 23188 investigations Intra-observer and device-dependent interobserver reliability of contrast-enhanced ultrasound for muscle perfusion quantification Quantitative evaluation of muscle perfusion with CEUS and with MR Dynamic contrast-enhanced ultrasound and elastography assess deltoid muscle integrity after reverse shoulder arthroplasty Contrast-enhanced ultrasound determines supraspinatus muscle atrophy after cuff repair and correlates to functional shoulder outcome Changes in the micro-circulation of skeletal muscle due to varied isometric exercise assessed by contrastenhanced ultrasound Cross-over trials in statistics in medicine: the first '25' years Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals Acute effects of citrulline supplementation on high-intensity strength and power performance: a systematic review and meta-analysis Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study Adverse gastrointestinal effects of arginine and related amino acids The AMANDUS project-advanced microperfusion assessed non-union diagnostics with contrast-enhanced ultrasound (CEUS) for the detection of infected lower extremity nonunions The EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): update 2011 on non-hepatic applications Quantitative contrastenhanced ultrasound imaging: a review of sources of variability Italian Society for Ultrasound in M, Biology Study Group on Ultrasound Contrast A. keywords: arginine; ceus; citrulline; contrast; effects; examination; muscle; perfusion; study; supplements; ultrasound cache: cord-334180-aqw9snt7.txt plain text: cord-334180-aqw9snt7.txt item: #389 of 449 id: cord-334711-58ygbyiz author: Hernández-Sánchez, Brizeida Raquel title: Psychological Factors that Lessen the Impact of COVID-19 on the Self-Employment Intention of Business Administration and Economics’ Students from Latin America date: 2020-07-22 words: 8580 flesch: 27 summary: The role of gender stereotypes in perceptions of entrepreneurs and intentions to become an entrepreneur Development and cross-cultural application of a specific instrument to measure entrepreneurial intentions Exploratory study of job insecurity and entrepreneurial intention as correlates of counterproductive work behavior Social Foundations of Thought and Action: A Social Cognitive Theory The Impact of Terrorism and Conflicts on Growth in Asia ADB Institute Discussion Paper No. 113; ADBI Institute Self-Employment and conflict in Colombia Danger zone entrepreneurs: The importance of resilience and self-efficacy for entrepreneurial intentions The open society assesses its enemies: Shocks, disasters and terrorist attacks Business vulnerability to earthquakes and other disasters Positive and negative postdisaster psychological adjustment among adult survivors of the Southeast Asian earthquake-tsunami Startups in times of crisis-A rapid response to the COVID-19 pandemic Entrepreneurs in dark ages: Persistence of females entrepreneurs in Afghanistan The empirical exploration of intrinsic motivational processes Motivation, personality, and development within embedded social contexts: An overview of self-determination theory Self-Determination theory and the facilitation of intrinsic motivation, social development, and well-being Exercise, physical activity, and self-determination theory: A systematic review Why the self-employed are happier: Evidence from 25 European countries Differentiating autonomy from individualism and independence: A self-determination theory perspective on internalization of cultural orientations and well-being Entrepreneurial intention among university students in Malaysia: Integrating self-determination theory and the theory of planned behavior The impact of autonomy on the relationship between mentoring and entrepreneurial intentions among youth in Germany, Kenya, and Uganda College students' entrepreneurial intention: Testing an integrated model of SDT and TPB The proactive component of organizational behavior: A measure and correlates Proactive Behavior in Organizations Personal initiative (PI): An active performance concept for work in the 21st century Modeling the antecedents of proactive behavior at work Proactive personality and proactive behaviour: Perspectives on person-situation interactions Self-Efficacy: Toward a unifying theory of behavioral change Proactive personality and entrepreneurial intention: Employment and student level as moderators Bin, P. Creativity, proactive personality, and entrepreneurial intention: The role of entrepreneurial alertness From entrepreneurial intentions to behavior: The role of anticipated regret and proactive personality Firms' proactiveness during the crisis: Evidence from European data Entrepreneurial potential and potential entrepreneurs The proactive personality disposition and entrepreneurial behavior among small company presidents What do proactive people do? The impact of entrepreneurship education: A study of Iranian students' entrepreneurial intentions and opportunity identification Determinants of entrepreneurial intent: A meta-analytic test and integration of competing models A systematic literature review on entrepreneurial intentions: Citation, thematic analyses, and research agenda The relationship of entrepreneurial traits, skill, and motivation to subsequentventure growth Personality aspects of entrepreneurship: A look at five meta-analyses Effects of emotional intelligence on entrepreneurial intention and self-efficacy A downside to the entrepreneurial personality? Psychological need satisfaction as a pre-determinant of entrepreneurial intentionality Basic psychological need satisfaction, need frustration, and need strength across four cultures Basic psychological need theory: Advancements, critical themes, and future directions On psychological growth and vulnerability: Basic psychological need satisfaction and need frustration as a unifying principle Predicting entrepreneurial intentions: Incremental validity of proactive personality and entrepreneurial self-efficacy as a moderator García-Pérez-de-Lema, D. The effects of personal abilities and self-efficacy on entrepreneurial intentions keywords: business; covid-19; entrepreneurship; intentions; need; optimism; pandemic; perception; personality; proactiveness; psychological; satisfaction; students; study cache: cord-334711-58ygbyiz.txt plain text: cord-334711-58ygbyiz.txt item: #390 of 449 id: cord-334849-8rblgq9b author: LoPresti, Marissa title: The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature date: 2020-08-12 words: 7295 flesch: 36 summary: Human host genetic studies on coronavirus have largely been candidate-driven to date (see Tables 1 and S2 and Figures 3 and 4 for details on human studies, including specific references), though many hypothesis-free studies on COVID-19 are in various phases of completion. 46 Following up these data through host genetic studies using case and controls will help further examine variants in these and other genes. keywords: coronavirus; cov-2; covid-19; disease; factors; genes; host; human; infection; receptor; sars; species; studies; susceptibility cache: cord-334849-8rblgq9b.txt plain text: cord-334849-8rblgq9b.txt item: #391 of 449 id: cord-335055-gzuug3p5 author: Kwiyolecha, Elizabeth title: Patterns of viral pathogens causing upper respiratory tract infections among symptomatic children in Mwanza, Tanzania date: 2020-10-28 words: 3312 flesch: 38 summary: A simulated clients approach Comparison of nasopharyngeal and oropharyngeal swabs for the diagnosis of eight respiratory viruses by real-time reverse transcription-PCR assays Evaluation of the Bruker MALDI Biotyper for identification of Gram-positive rods-Development of a diagnostic algorithm for the clinical laboratory Performance Standards for Antimicrobial Susceptibility Testing Validation of a multiplex reverse transcriptase PCR ELISA for the detection of 19 respiratory tract pathogens Evaluation of a multiplex reverse transcriptase PCR ELISA for the detection of nine respiratory tract pathogens Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing Seasonality of viral infections: Mechanisms and unknowns An explanation for the seasonality of acute upper respiratory tract viral infections The seasonality of rhinovirus infections and its implications for clinical recognition Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: A retrospective study of 27 years Aetiology of acute respiratory infections in children under five years in Nakuru, Kenya Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs Risk factors for acute respiratory tract infections in under-five children in Enugu Southeast Nigeria Respiratory tract infections in the tropics Seasonal variations of respiratory viruses detected from children with respiratory tract infections in Riyadh, Saudi Arabia Epidemiology and seasonality of respiratory tract virus infections in the tropics Predictors of disease complications and treatment outcome among patients with chronic suppurative otitis media attending a tertiary hospital Factors associated with colonization of Streptococcus pneumoniae among under-fives attending clinic in Mwanza City Rhinovirus: more than just a common cold virus Rhinovirus infections in the upper airway An update on the pathophysiology of rhinovirus upper respiratory tract infections Adenoviral infections in children: The impact of rapid diagnosis Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai Incubation periods of acute respiratory viral infections: A systematic review Estimating incubation period distributions with coarse data The authors acknowledge the assistance provided by department of pediatrics Mainz University, the department of Microbiology and Immunology-CUHAS-Bugando, and the department of pediatrics and child health-CUHAS-Bugando. key: cord-335055-gzuug3p5 authors: Kwiyolecha, Elizabeth; Groendahl, Britta; Okamo, Bernard; Kayange, Neema; Manyama, Festo; Kidenya, Benson R.; Mahamba, Dina C.; Msanga, Delfina R.; Gehring, Stephan; Majigo, Mtebe; Mshana, Stephen E.; Mirambo, Mariam M. title: Patterns of viral pathogens causing upper respiratory tract infections among symptomatic children in Mwanza, Tanzania date: 2020-10-28 journal: Sci Rep DOI: 10.1038/s41598-020-74555-2 sha: doc_id: 335055 cord_uid: gzuug3p5 Upper-respiratory tract infections (URTI) are the leading causes of childhood morbidities. keywords: age; children; ear; infections; pathogens; rhinovirus; study; tract; urti; viruses cache: cord-335055-gzuug3p5.txt plain text: cord-335055-gzuug3p5.txt item: #392 of 449 id: cord-335109-czheponh author: Meidenbauer, Kimberly L. title: The Affective Benefits of Nature Exposure: What’s Nature Got to Do with It? date: 2020-09-18 words: 9535 flesch: 43 summary: Unfortunately, there were very few strongly liked urban images or strongly disliked nature images. For nature images this correlation was r = 0.96 and for urban images the correlation was r = 0.95. keywords: affect; environments; images; nature; participants; preference; ratings; study; urban cache: cord-335109-czheponh.txt plain text: cord-335109-czheponh.txt item: #393 of 449 id: cord-335141-ag3j8obh author: Higgins, G.C. title: FFP3 reusable respirators for COVID-19; adequate and suitable in the healthcare setting date: 2020-06-30 words: 22066 flesch: 48 summary: When asked Would you think other patients would like to have a similar AR leaflet before surgery and Would you like to see further AR leaflets to be developed in the future? In addition to those directly working in the respiratory, infectious, cardiology, nephrology, psychology, and ICU departments and COVID-19 patients, all members of the general population may encounter the new coronavirus. keywords: article; authors; care; clinic; covid-19; data; face; flap; free; hand; health; hospital; information; lymphedema; lymphorrhea; nhs; pandemic; patients; plastic; plastic surgery; practice; publication; reconstruction; risk; scar; service; skin; social; staff; study; surgeons; surgery; therapy; time; trainees; training; trauma; treatment; use; wound cache: cord-335141-ag3j8obh.txt plain text: cord-335141-ag3j8obh.txt item: #394 of 449 id: cord-335251-w6k4fnpo author: Nielsen, Morten Birkeland title: Organizational Prevention and Management Strategies for Workplace Aggression Among Child Protection Workers: A Project Protocol for the Oslo Workplace Aggression Survey (OWAS) date: 2020-06-30 words: 7551 flesch: 35 summary: The two main categories of workplace aggression are physical violence and psychological aggression. Previous research has established exposure to workplace aggression as a significant risk factor for employee functioning, well-being, and health. keywords: aggression; bullying; climate; data; employees; health; project; safety; study; survey; violence; workplace cache: cord-335251-w6k4fnpo.txt plain text: cord-335251-w6k4fnpo.txt item: #395 of 449 id: cord-335723-7wefotwe author: Johann, Alexandra title: The study protocol: Neuroendocrinology and (epi-) genetics of female reproductive transition phase mood disorder - an observational, longitudinal study from pregnancy to postpartum date: 2020-10-09 words: 4435 flesch: 35 summary: In line with these findings, higher placental corticotropin-releasing hormone (pCRH) levels in mid to late pregnancy have been found to be a strong predictor of postpartum depression (PPD) A notable key player associated with postpartum depression might also be one of the metabolites of progesterone, allopregnanolone: Lower rates in the second and third trimester have been linked to an elevated risk of PPD keywords: analyses; blood; data; depression; postpartum; ppd; pregnancy; risk; study; symptoms; weeks; women cache: cord-335723-7wefotwe.txt plain text: cord-335723-7wefotwe.txt item: #396 of 449 id: cord-335975-m6lkrehi author: None title: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date: 2018-02-05 words: 89523 flesch: 50 summary: The aim of this study was to compare the outcome of ICU patients having received carbapenems to those having received a carbapenem-sparing agent (CSA). Conclusion: Severe hypoxemia, independently from ARDS, worsens the prognosis of ICU patients. keywords: acute; admission; age; aim; analysis; antibiotic; ards patients; blood; brain; cardiac; care; cases; characteristics; children; clinical; conclusion; criteria; data; days; death; diagnosis; disease; drug; duration; factors; failure; fig; group; high; hospital; icu; icu admission; icu mortality; icu patients; impact; incidence; increase; infection; intensive; introduction; intubation; january; length; level; low; management; mean; median; medical; methods; min; mortality; n =; niv; non; outcome; p =; patients; period; pneumonia; post; pressure; prognosis; rate; respiratory; results; resuscitation; risk; score; sepsis; septic; severity; shock; shock patients; stay; studies; study; study period; therapy; time; treatment; unit; use; vap; ventilation; volume; vs.; years cache: cord-335975-m6lkrehi.txt plain text: cord-335975-m6lkrehi.txt item: #397 of 449 id: cord-336000-v88bq4bx author: Barco, Stefano title: Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial date: 2020-09-09 words: 20408 flesch: 38 summary: OVID may increase the level of safety compared to standard of care for study patients because frequent telephone visits are planned (Day 3, 7, 14, 30, 90) . Source data must be available at the site to document the existence of the study participants and substantiate the integrity of study data collected. keywords: acute; analysis; anti; bleeding; center; covid-19; covid-19 patients; data; days; dose; enoxaparin; events; hospitalization; information; investigator; medical; outcome; patients; risk; study; study center; test; thromboprophylaxis; treatment; trial; use; vte cache: cord-336000-v88bq4bx.txt plain text: cord-336000-v88bq4bx.txt item: #398 of 449 id: cord-336131-7xqi1mnx author: Gupta, Manika title: Preclinical Studies of MSC-Derived Extracellular Vesicles to Treat or Prevent Graft Versus Host Disease: a Systematic Review of the Literature date: 2020-11-07 words: 4708 flesch: 41 summary: Dosing of EVs and route of administration remain inconsistent, however, and scalability of EV isolation for clinical studies remains a challenge. Translation to clinical studies should be accelerated given the potential promise and benefits of MSC-EVs in this setting. keywords: cells; evs; gvhd; mesenchymal; msc; mscs; review; score; studies; study; treatment cache: cord-336131-7xqi1mnx.txt plain text: cord-336131-7xqi1mnx.txt item: #399 of 449 id: cord-336306-hvy9ukhh author: Zhu, Jieyun title: Clinical characteristics of 3,062 COVID‐19 patients: a meta‐analysis date: 2020-04-15 words: 2119 flesch: 50 summary: We also performed a manual search of the references lists of included studies to avoid omitting any eligible study. This study has several strengths, including its large sample size and high quality of included studies. keywords: analysis; covid-19; meta; patients; studies; study cache: cord-336306-hvy9ukhh.txt plain text: cord-336306-hvy9ukhh.txt item: #400 of 449 id: cord-336934-57kbz29c author: Kesteman, Thomas title: Investigating Pneumonia Etiology Among Refugees and the Lebanese population (PEARL): A study protocol date: 2019-06-13 words: 9615 flesch: 44 summary: The authors rightly stress the limitations of 'blindly' applying etiology data from other studies to this population. The authors rightly stress the limitations of 'blindly' applying etiology data from other studies to this population. keywords: action; age; blood; cap; cases; children; controls; data; etiology; patients; pneumonia; population; protocol; samples; study; years cache: cord-336934-57kbz29c.txt plain text: cord-336934-57kbz29c.txt item: #401 of 449 id: cord-337316-ialg7d7e author: Cori, Liliana title: Risk Perception of Air Pollution: A Systematic Review Focused on Particulate Matter Exposure date: 2020-09-03 words: 9409 flesch: 41 summary: [70] , in six states in the USA, together with air pollution perception, symptoms and behaviors were considered to elucidate the consequences of individual behavioral change in terms of coping with smog pollution in the first article [34] and the consequences of alerts in the second [70] , Several research papers have dealt with the issue of risk communication and alerts and their effects on the population's risk perception [41, 48, 69, 71, 73] . The purpose of this study was to explore studies that analyse people’s perception, together with the measurement of air pollution, in order to elucidate the relationship between them. keywords: air; air pollution; articles; data; exposure; health; n =; perception; pollution; public; review; risk; studies; study cache: cord-337316-ialg7d7e.txt plain text: cord-337316-ialg7d7e.txt item: #402 of 449 id: cord-337663-ow1l18li author: Qu, Liang G. title: Scoping review: hotspots for COVID-19 urological research: what is being published and from where? date: 2020-09-09 words: 4705 flesch: 42 summary: On multivariable regression, greater experience level (OR = 1.76, 95% CI 1.01-3.13) and a need to manage COVID-19 patients in the urology department (OR = 2.31, 95% CI 1.20-4.65) adversely affected the quality of their work. Ultrastructural evidence for direct renal infection with SARS-CoV-2 SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens No evidence of SARS-CoV-2 in semen of males recovering from COVID-19 Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients No SARS-CoV-2 in expressed prostatic secretion of patients with coronavirus disease 2019: a descriptive multicentre study in China Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19 Expression of ACE2, the SARS-CoV-2 receptor, and TMPRSS2 in prostate epithelial cells 2020) scRNA-seq profiling of human testes reveals the presence of the ACE2 receptor, a target for SARS-CoV-2 infection in spermatogonia The ACE2 expression in Sertoli cells and Germ cells may cause male reproductive disorder after SARS-CoV-2 Infection Multiple expression assessments of ACE2 and TMPRSS2 SARS-CoV-2 entry molecules in the urinary tract and their associations with clinical manifestations of Suppression of androgen receptor (AR)-ACE2/ TMPRSS2 axis by AR antagonists may be therapeutically beneficial for male COVID patients Effect of SARS-CoV-2 infection upon male gonadal function: a single center-based study The majority of male patients with COVID-19 present low testosterone levels on admission to Intensive Care in Hamburg, Germany: a retrospective cohort study Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (n = 4532) keywords: cov-2; covid-19; pandemic; patients; research; sars; studies; study; urology cache: cord-337663-ow1l18li.txt plain text: cord-337663-ow1l18li.txt item: #403 of 449 id: cord-338332-msjtncek author: Sharifian, Neika title: Social Relationships and Adaptation in Later Life date: 2020-09-18 words: 17299 flesch: 31 summary: Individuals engage in social relationships across the life course and it is important to note that age-related changes in the structure, function and quality of social relations occur in later life. Not the quantity but the quality of social interactions is protective up to 15 years later Social relations: an examination of social networks, social support, and sense of control Social networks in adult life and a preliminary examination of the convoy model The convoy model: explaining social relations from a multidisciplinary perspective The effect of social relations with children on the education-health link in men and women aged 40 and over Social relations and technology: continuity, context, and change Convoys of social relations: cohort similarities and differences over 25 years Social relations and mortality: a more nuanced approach Parental child-rearing strategies influence self-regulation, socio-emotional adjustment, and psychopathology in early adulthood: evidence from a retrospective cohort study On the incomplete architecture of human ontogeny: selection, optimization, and compensation as foundation of developmental theory Handbook of Child Psychology: keywords: adults; age; et al; family; friends; health; life; loneliness; network; outcomes; quality; relations; relationships; research; social; study; support; use cache: cord-338332-msjtncek.txt plain text: cord-338332-msjtncek.txt item: #404 of 449 id: cord-338730-49ai51ah author: Baashar, Yahia title: Customer relationship management systems (CRMS) in the healthcare environment: A systematic literature review date: 2020-08-31 words: 7561 flesch: 34 summary: Summary of e-CRM studies in healthcare Year Author Brief Description Findings Explored e-CRM through PPS, and performed costbenefit analysis on the quality and performance of PPS. Our analysis of the selected studies revealed three main categories of CRM research in the healthcare sector: (i) e-CRM (Web-based CRM); (2) implementing CRMS; and (3) adopting CRMS. keywords: authors; crm; crms; customer; data; health; healthcare; implementation; information; management; medical; relationship; research; review; studies; study cache: cord-338730-49ai51ah.txt plain text: cord-338730-49ai51ah.txt item: #405 of 449 id: cord-338741-gy3ovkrt author: Sethi, Atin title: Evaluation of Current Therapies for COVID-19 Treatment date: 2020-07-22 words: 5592 flesch: 44 summary: The authors suggested that physicians should test for SARS-CoV-2 antibodies in hospitalized patients before treatment with convalescent plasma. In patients with mechanical ventilation, dexamethasone reduced mortality by 1/3, and by 1/5 in those receiving oxygen alone. keywords: control; cov-2; covid-19; efficacy; hydroxychloroquine; patients; sars; study; treatment; trial; use cache: cord-338741-gy3ovkrt.txt plain text: cord-338741-gy3ovkrt.txt item: #406 of 449 id: cord-338889-7hd3iibk author: Solbakk, Jan Helge title: Back to WHAT? The role of research ethics in pandemic times date: 2020-11-03 words: 11708 flesch: 47 summary: In this paper we disentangle some of the arguments put forward in the ongoing debate about Covid-19 human challenge studies (CHIs) and the concomitant role of health-related research ethics in pandemic times. In the next paragraph of this paper we will examine and critique in detail four position statements advocating the epistemological and ethical justifiability of conducting Covid-19 CHI-studies: P. Singer and R.Y. Chappell's, Pandemic ethics: The case for experiments on human volunteers 12 ; the report, Key criteria for the ethical acceptability of COVID-19 human challenge studies, issued by a working group set up by WHO 13 ; the Policy Forum statement, Ethics of controlled human infection to study by Shah, Miller, Darton et al.; 14 and Jamrozik and Selgelid's statement, In addition, we will consider other recent papers advocating the use of Covid-19 CHIs studies. keywords: challenge; cov-2; covid-19; et al; ethical; ethics; human; infection; pandemic; participants; research; rights; risk; sars; studies; study; trial; uncertainty; vaccine; virus cache: cord-338889-7hd3iibk.txt plain text: cord-338889-7hd3iibk.txt item: #407 of 449 id: cord-340128-qxkopvot author: Schreibauer, Elena Christina title: Work-Related Psychosocial Stress in Small and Medium-Sized Enterprises: An Integrative Review date: 2020-10-13 words: 6976 flesch: 43 summary: Data of included studies were analyzed and mapped into five themes: “work content and task”, “organization of work”, “social relations”, “working environment” and “new forms of work”. However, it was not suitable for a classic systematic review design and resulted in a heterogeneous sample of included studies and a high number of irrelevant hits, particularly in the database Business Source Premiere which identified numerous entries on financial stress not related to our research objective. keywords: enterprises; factors; health; new; psychosocial; review; smes; stress; studies; study; work; working cache: cord-340128-qxkopvot.txt plain text: cord-340128-qxkopvot.txt item: #408 of 449 id: cord-340284-xo7q4dqr author: Pappa, Sofia title: Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis date: 2020-05-08 words: 2969 flesch: 38 summary: Furthermore, low risk of bias studies (n=9) revealed a total pooled anxiety prevalence of 24·05% (95% CI 16·84-32·07, I 2 =99%). Studies scoring ≥3 points were regarded as low risk of bias, compared to the studies assessed with <3 points that were regarded as high risk of bias. keywords: analysis; anxiety; covid-19; depression; health; prevalence; studies cache: cord-340284-xo7q4dqr.txt plain text: cord-340284-xo7q4dqr.txt item: #409 of 449 id: cord-341063-3rqnu5bu author: None title: 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date: 2018-03-29 words: 98736 flesch: 48 summary: Since altered liver function has also been described in ICU patients without sepsis [1, 2] , the influence of sepsis may be overestimated. The aim of this work is to analyze the connection between serum and fecal levels of AMM in ICU patients. keywords: acute; admission; adult patients; age; aim; aki; analysis; ards; arrest; assessment; baseline; blood; brain; cardiac; care; care patients; care unit; cases; changes; clinical; cohort; complications; conclusions; control; correlation; criteria; critical; data; day mortality; days; decrease; diagnosis; difference; discharge; duration; dysfunction; early; effect; emergency; end; factors; failure; fig; flow; fluid; following; group; hospital; hospital mortality; hours; icu admission; icu mortality; icu patients; icu stay; impact; incidence; increase; infection; injury; introduction; length; levels; lung; mean; median; medical; methods; min; model; months; mortality; non; organ; outcome; p<0.001; parameters; patients; period; population; post; pressure; protocol; rate; renal; results; risk; risk patients; score; sepsis; septic; severity; shock; significant; sofa; stay; studies; study; support; surgery; surgery patients; survival; survivors; table; test; therapy; time; total; transfusion; treatment; unit; use; value; ventilation; volume; years cache: cord-341063-3rqnu5bu.txt plain text: cord-341063-3rqnu5bu.txt item: #410 of 449 id: cord-341097-c96hm610 author: Mayer, Craig S. title: Analysis of data dictionary formats of HIV clinical trials date: 2020-10-05 words: 6901 flesch: 54 summary: To demonstrate some examples of study data elements, Table 1 shows the element data dictionary from study NCT00099359: 'Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission.' We also describe relevant standards for study data dictionaries. keywords: clinical; common; data; dictionaries; dictionary; elements; format; hiv; sharing; studies; study; values cache: cord-341097-c96hm610.txt plain text: cord-341097-c96hm610.txt item: #411 of 449 id: cord-341745-2txzi7kb author: Singh, S. title: Efficacy and Safety of Hydroxychloroquine and Chloroquine for COVID-19: A systematic review date: 2020-05-26 words: 4773 flesch: 45 summary: CONCLUSIONS: Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID-19 patients and raises questions about potential harm from QT prolongation and increased mortality. Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID -19 patients and raises questions about potential harm from QT prolongation and increased mortality. keywords: covid-19; hydroxychloroquine; medrxiv; patients; preprint; review; studies cache: cord-341745-2txzi7kb.txt plain text: cord-341745-2txzi7kb.txt item: #412 of 449 id: cord-342210-r8vxz5vu author: Mukherjee, Pranab K. title: Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections date: 2017-01-14 words: 4859 flesch: 43 summary: Subjectlevel characteristics were summarized per study group, age, gender, prior influenza vaccine status and medications taken for symptom relief. Healthy adults (18–45 years of age) were randomized into ARMS-I or placebo group (50 subjects each). keywords: arms; clinical; duration; group; influenza; participants; placebo; study; symptoms; uris cache: cord-342210-r8vxz5vu.txt plain text: cord-342210-r8vxz5vu.txt item: #413 of 449 id: cord-343844-xe9tdjrm author: Guaiana, Giuseppe title: A Systematic Review of the Use of Telepsychiatry in Depression date: 2020-10-10 words: 3063 flesch: 40 summary: References Canadian Network for Mood and Anxiety Treatments (CANMAT) COVID-19 pandemic-a focused review for clinicians Ethical practice in telehealth and telemedicine Six-month postintervention depression and disability outcomes of in-home telehealth problem-solving therapy for depressed, low-income homebound older adults Feasibility and acceptability of clinic-based telepsychiatry for low-income Hispanic primary care patients Psychotherapy for depression in older veterans via telemedicine: A randomized, open-label, non-inferiority trial Psychotherapy for depression in older veterans via telemedicine: Effect on quality of life, satisfaction, treatment credibility, and service delivery perception Trajectory of cost overtime after psychotherapy for depression in older Veterans via telemedicine Cost-effectiveness of behavioural activation for depression in older adult veterans: In person-care versus telehealth A randomized trial of telemedicine-based collaborative care for depression A budget impact analysis of telemedicine-based collaborative care for depression Practicebased versus telemedicine-based collaborative care for depression in rural federally qualified health centers: A pragmatic randomized comparative effectiveness trial Telemedicine for depression: A systematic review Review of key telepsychiatry outcomes Telepsychiatry: Who, what, where, and how Home-based telebehavioral health for U.S. military personnel and veterans with depression: A randomized controlled trial Use of standard webcam and internet equipment for telepsychiatry treatment of depression among underserved Hispanics OTN Annual report 2017/18. Study eligibility criteria included: MDD as the condition of interest, use of televideo technology, randomized controlled trials (RCTs), Adult (18 years or older) population, any clinical setting, and any healthcare professional providing care. keywords: care; cost; telepsychiatry; televideo; treatment cache: cord-343844-xe9tdjrm.txt plain text: cord-343844-xe9tdjrm.txt item: #414 of 449 id: cord-344075-ucd6ooob author: Bartoszek, Adrian title: Mental Well-Being (Depression, Loneliness, Insomnia, Daily Life Fatigue) during COVID-19 Related Home-Confinement—A Study from Poland date: 2020-10-12 words: 4520 flesch: 46 summary: Respondents who started taking any new drugs during COVID-19 home confinement had higher outcomes in all questionnaires. To extend the scope of the research on the topic, we decided to include some further factors that may be associated with varying mental health outcomes during COVID-19 home confinement. keywords: confinement; covid-19; depression; fatigue; health; home; insomnia; pandemic; study cache: cord-344075-ucd6ooob.txt plain text: cord-344075-ucd6ooob.txt item: #415 of 449 id: cord-344498-mwgccbfo author: Casado-Aranda, Luis-Alberto title: Analysis of the Scientific Production of the Effect of COVID-19 on the Environment: A Bibliometric Study date: 2020-11-03 words: 5784 flesch: 34 summary: This study is not only a first in the evolution of COVID-19 research from the specific perspective of environmental studies, but will be of extreme utility for information professionals to disseminate objective and quality coverage on the effects of the virus on the environment. Thus the co-word analysis applied text-mining techniques to the titles, abstracts, and keywords leading to the design, based on fundamental bibliometric indicators such as the number of publications, of a strategic diagram illustrating the main themes of interest related to the issue of environment in COVID-19 research. keywords: air; analysis; covid-19; effects; environmental; et al; information; pandemic; quality; research; science; smart; studies; study cache: cord-344498-mwgccbfo.txt plain text: cord-344498-mwgccbfo.txt item: #416 of 449 id: cord-344902-bittqpyo author: Scott, Jennifer title: A systematic review of the physical activity levels of acutely ill older adults in Hospital At Home settings: an under-researched field date: 2020-10-15 words: 4910 flesch: 37 summary: Physical activity as step count Eight studies used pedometers or accelerometers to record 24 h step count as a measure of physical activity ( Functional change between admission and discharge was reported in 4 studies, the results extracted are summarised in Table 5 . The physical activity outcomes of the studies were grouped according to their method of measuring physical activity levels and reporting format. keywords: activity; acute; hah; home; hospital; levels; patients; research; results; review; studies cache: cord-344902-bittqpyo.txt plain text: cord-344902-bittqpyo.txt item: #417 of 449 id: cord-344988-09vpehvf author: Overbeck, Silke title: Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases date: 2008-02-05 words: 7948 flesch: 36 summary: Free Radic Zinc supplementation reconstitutes the production of interferon-α by leukocytes from elderly persons Dysregulation between TH1 and TH2 T cell subpopulations in the elderly Zinc, insulin and diabetes Changes in serum selenium, copper, zinc levels and Cu/Zn ratio in patients with pulmonary tuberculosis during therapy Zinc deficiency and supplementation in HIV/AIDS Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T--lymphocyte proliferation and nuclear protein kinase C Hyperzincuria in individuals with insulin-dependent diabetes mellitus: concurrent zinc status and the effect of high-dose zinc supplementation A zinc dependent epitope of the molecule of thymulin, a thymic hormone Effect of zinc and vitamin A supplementation on antibody responses to a pneumococcal conjugate vaccine in HIV-positive injection drug users: a randomized trial Interference in the development of a secondary immune response in mice by zinc deprivation: persistence of effects Effects of zinc supplementation in patients with type 1 diabetes The role of assembly in insulin's biosynthesis Zinc and the gene Beneficial effects of oral zinc supplementation on the immune response of old people Plasma zinc concentrations are depressed during the acute phase response in children with falciparum malaria Transcriptional regulation of the mouse metallothionein-I gene by heavy metals Bioavailability of zinc in several sources of zinc oxide, zinc sulfate, and zinc metal Effect of oral zinc supplementation on the cell mediated immunity in lepromatous leprosy Role of zinc in insulin biosynthesis: some possible zinc-insulin interactions in the pancreatic B-cell Zinc in developmental biology: the role of metal dependent transcription regulation Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: effects of an oral zinc supplementation Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania Zinc and the risk for infectious disease An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection Regeneration of T-cell helper function in zinc-deficient adult mice Interrelationships between zinc and immune function Zinc deficiency and the immune function Reprogramming of the immune system during zinc deficiency Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of Bcl-2/Bax ratio Treatment of acrodermatitis enteropathica with zinc sulphate Effect of severe zinc deficiency on activity of intestinal disaccharidases and 3-hydroxy-3-methy-glutaryl coenzyme A reductase in the rat In vitro activity of zinc salts against human rhinoviruses Serum zinc/copper ratio in subtypes of leprosy and effect of oral zinc therapy on reactional states Transport of electrolytes, water, and glucose in zinc deficiency Kinetic aspects of compartmental storage and secretion of insulin and zinc A randomised controlled trial of oral zinc on the immune response to tuberculosis in HIV-infected patients Zinc as a second messenger of mitogenic induction. Effects on diadenosine tetraphosphate (Ap4A) and DNA synthesis Flow cytometric measurement of labile zinc in peripheral blood mononuclear cells Correlation between zinc status and immune function in the elderly Signal transduction in monocytes: the role of zinc ions Imbalance between pro-oxidant and pro-antioxidant functions of zinc in disease Inhibition of HIV-1 infection by zinc group metal compounds Effect of intragastric pH on the absorption of oral zinc acetate and zinc oxide in young healthy volunteers Zinc aspartate in vivo and in vitro modulation of reactive oxygen species production by human neutrophils and monocytes Zinc in the treatment of acute diarrhea: current status and assessment Efficacy of zinc against common cold viruses: an overview Zinc-altered immune function Zinc and the common cold: a meta-analysis revisited A meta--analysis of zinc salts lozenges and the common cold Intestinal and systemic immune responses to an oral cholera toxoid B subunit whole-cell vaccine administered during zinc supplementation A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxycillin and clarithromycin increases the cure rate of Helicobacter pylori infection Copper and zinc inhibit the metabolism of prostaglandin by the human uterus The effect of zinc supplementation on the treatment of chronic hepatitis C patients with interferon and ribavirin Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides Zinc ions inhibit replication of rhinoviruses The impaired immune response to diphtheria vaccination in elderly chronic hemodialysis patients is related to zinc deficiency Transgenic copper/zinc superoxide dismutase modulates susceptibility to type 1 diabetes The mechanism of the antiherpetic activity of zinc sulphate The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children Identification of SLC39A4, a gene involved in acrodermatitis enteropathica Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute--phase response Absorption of zinc in acrodermatifis enteropathica Dietary factors influencing zinc absorption keywords: cells; deficiency; effect; function; immune; infection; oral; patients; production; response; studies; study; supplementation; therapy; treatment; zinc; zinc supplementation cache: cord-344988-09vpehvf.txt plain text: cord-344988-09vpehvf.txt item: #418 of 449 id: cord-345086-vq4ei1do author: Johnston, Marjorie C. title: Physical Disease and Resilient Outcomes: A Systematic Review of Resilience Definitions and Study Methods date: 2015-04-30 words: 5327 flesch: 46 summary: Objective The aim was to summarize the range of definitions of physical disease resilience and the approaches taken to study it in studies examining physical disease and its relationship to resilient outcomes. Conclusion This work begins building consensus as to the approach to take when defining and measuring physical disease resilience. keywords: adversity; disease; outcomes; resilience; studies; study cache: cord-345086-vq4ei1do.txt plain text: cord-345086-vq4ei1do.txt item: #419 of 449 id: cord-345108-gtp36snr author: Al-Ani, Raid M. title: Prevalence of Anosmia and Ageusia in Patients with COVID-19 at a Primary Health Center, Doha, Qatar date: 2020-08-19 words: 3255 flesch: 58 summary: The study was a retrospective analysis of the prevalence of the anosmia and ageusia in COVID-19 patients. The mystery and the miracle Organization WH (2020) WHO Director-General's remarks at the media briefing on 2019-nCoV on 11 Covid-19: WHO declares pandemic because of 'alarming levels' of spread, severity, and inaction Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Clinical features of 69 cases with coronavirus disease in Wuhan China COVID-19 and Anosmia in Tehran Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Loss of sense of smell as marker of COVID-19 infection, ENT UK Olfactory and gustatory dysfunction as an early identifier of COVID-19 in adults and children: An international multicenter study Olfactory dysfunction and sinonasal symptomatology in COVID-19: prevalence, severity, timing, and associated characteristics Olfactory and gustatory outcomes in COVID-19: A prospective evaluation in nonhospitalized subjects The prevalence of olfactory and gustatory dysfunction in COVID-19 patients: a systematic review and meta-analysis Prevalence and recovery from olfactory and gustatory dysfunctions in Covid-19 infection: a prospective multicenter study Smell and taste abnormalities due to keywords: ageusia; anosmia; covid-19; disease; patients; study cache: cord-345108-gtp36snr.txt plain text: cord-345108-gtp36snr.txt item: #420 of 449 id: cord-345454-r1ymzk6n author: Levesque, J. title: A note on COVID-19 seroprevalence studies: a meta-analysis using hierarchical modelling date: 2020-05-06 words: 3633 flesch: 57 summary: We construct our datasets from scientific preprints, manufacturers' specifications, and transcripts from interviews with study authors published in the news media. COVID-19 antibody test manufactured in China by Hangzhou Biotest Biotech Co., Ltd., and distributed in the United States by Premier Biotech, Inc. keywords: antibody; county; covid-19; prevalence; results; studies; study; test cache: cord-345454-r1ymzk6n.txt plain text: cord-345454-r1ymzk6n.txt item: #421 of 449 id: cord-345611-xv62h83a author: Cavalcanti, A. B. title: Hydroxychloroquine alone or in combination with azithromycin to prevent major clinical events in hospitalised patients with coronavirus infection (COVID-19): rationale and design of a randomised, controlled clinical trial date: 2020-05-26 words: 4292 flesch: 42 summary: key: cord-345611-xv62h83a authors: Cavalcanti, A. B.; Zampieri, F. G.; Azevedo, L. C.; Rosa, R. G.; Avezum, A.; Veiga, V. C.; Lopes, R. D.; Kawano-Dourado, L.; Damiani, L. P.; Pereira, A. J.; Serpa Neto, A.; Furtado, R.; Tomazini, B.; Bozza, F. A.; Maia, I. S.; Falavigna, M.; Lisboa, T. C.; Fonseca, H.; Machado, F. R.; Berwanger, O.; Investigators, COALITION COVID-19 Brazil I title: Hydroxychloroquine alone or in combination with azithromycin to prevent major clinical events in hospitalised patients with coronavirus infection (COVID-19): rationale and design of a randomised, controlled clinical trial date: 2020-05-26 journal: nan DOI: 10.1101/2020.05.19.20106997 sha: doc_id: 345611 cord_uid: xv62h83a Introduction: Hydroxychloroquine and its combination with azithromycin have been suggested to improve viral clearance in patients with COVID-19, but its effect on clinical outcomes remains uncertain. https://doi.org/10.1101/2020.05.19.20106997 doi: medRxiv preprint Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomised clinical trial Online ahead of print Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in P atients With COVID-19 in New York State Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomised Clinical Trial Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Statement: Defining standard protocol items for clinical trials A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Repeated assessments of results in clinical trials of cancer treatment Design and analysis of randomized clinical trials requiring prolonged observation of each patient. keywords: covid-19; days; hydroxychloroquine; license; medrxiv; patients; preprint; protocol; study cache: cord-345611-xv62h83a.txt plain text: cord-345611-xv62h83a.txt item: #422 of 449 id: cord-346098-gj10adoq author: Oh, Ga-Eun (Grace) title: When dessert comes close: The effects of anticipating indulgent consumption and dietary restraint on healthy food preference at restaurants date: 2020-07-16 words: 9964 flesch: 32 summary: Although previous research has examined the effect of anticipating healthy food consumption (Hur and Jang, 2015; Sim and Cheon, 2019) , the impact of anticipating indulgent food consumption has received minimal attention (see Zemack-Rugar and Corus, 2018 for an exception). In the absence of nutrition information, consumers might not be able to find an item that matches their preference for healthy food consumption (H2). keywords: anticipation; consumption; eaters; effect; food; information; nutrition; participants; preference; restraint; study cache: cord-346098-gj10adoq.txt plain text: cord-346098-gj10adoq.txt item: #423 of 449 id: cord-346327-dgpkiqgu author: Ferriss, J. Stuart title: Systematic Review of Intraoperative Assessment Tools in Minimally Invasive Gynecologic Surgery date: 2020-10-18 words: 2014 flesch: 36 summary: Conclusions : Procedure specific intraoperative assessment tools for MIGS cases are more thoroughly evaluated compared to global tools; however, poor-quality studies and borderline reliability limit their use. Well designed, controlled studies evaluating the effectiveness of intraoperative assessment tools in MIGS are needed. keywords: assessment; intraoperative; studies; study; tools cache: cord-346327-dgpkiqgu.txt plain text: cord-346327-dgpkiqgu.txt item: #424 of 449 id: cord-347207-1u4i6qmc author: Almomani, Huda Y. title: Randomised controlled trial of pharmacist-led patient counselling in controlling hypoglycaemic attacks in older adults with type 2 diabetes mellitus (rose-adam): A study protocol date: 2020-07-29 words: 4461 flesch: 47 summary: Several studies have established the important positive role of educational interventions on achieving glycaemic control and other clinical outcomes, however, there is still a lack in studies that evaluate the impact of such type of interventions on hypoglycaemia risk in elderly patients with type 2 diabetes. 19 56 There are several studies on the association between hypoglycaemia and patient 57 characteristics such as patients' perspectives and attitudes towards diabetes management 58 skills, self-monitoring of blood glucose, and non-adherence to anti-diabetic medications in 59 Jordanian population. keywords: care; diabetes; hypoglycaemia; intervention; participants; patients; study; trial; type cache: cord-347207-1u4i6qmc.txt plain text: cord-347207-1u4i6qmc.txt item: #425 of 449 id: cord-348490-dqabq6d8 author: Maeder, Muriel N. title: Sickle-cell disease in febrile children living in a rural village of Madagascar and association with malaria and respiratory infections date: 2016-12-01 words: 4291 flesch: 44 summary: Prevalence of SCD among febrile children was 2.4% (95% CI, 1.5–3.7%) and that of SCT was 23.8% (95% CI, 20.9–26.9%). However, the clinical significance of viral detection in biological samples from patients with respiratory infections remains often unclear. keywords: cell; children; infection; malaria; patients; scd; sickle; study cache: cord-348490-dqabq6d8.txt plain text: cord-348490-dqabq6d8.txt item: #426 of 449 id: cord-348570-plds5kbn author: Buneviciene, Inesa title: Can mHealth interventions improve quality of life of cancer patients? A systematic review and meta-analysis date: 2020-10-20 words: 5440 flesch: 35 summary: The effects of mindfulness-based stress reduction on psychosocial outcomes and quality of life in early-stage breast cancer patients: a randomized trial Digital Phenotyping in Patients with Spine Disease: A Novel Approach to Quantifying Mobility and Quality of Life 3 Digital Phenotyping: A Novel Method for Quality of Life Assessment in Patients with Brain Tumors Opportunities and challenges in the collection and analysis of digital phenotyping data Cognitive Behavior Therapy for Patients With Cancer The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis Efficacy of Blended Cognitive Behavior Therapy for High Fear of Recurrence in Breast, Prostate, and Colorectal Cancer Survivors: The SWORD Study, a Randomized Controlled Trial Using cognitive behavioural therapy in practice: qualitative study of family physicians' experiences There's an App for That: Information Technology Applications for Cognitive Behavioral Practitioners Review of cognitive behavioural therapy mobile apps using a reference architecture embedded in the patient-provider relationship Digital health and perioperative care The Functional Assessment of Cancer Therapy scale: development and validation of the general measure Life satisfaction in young adults with cancer and the role of sociodemographic, medical, and psychosocial factors: Results of a longitudinal study Perceived social support and its impact on depression and health-related quality of life: a comparison between cancer patients and general population The Relationship Between Coping Strategies, Quality of Life, and Mood in Patients with Incurable Cancer Longitudinal Effects of Social Support and Adaptive Coping on the Emotional Well-Being of Survivors of Localized Prostate Cancer Coping response following a diagnosis of breast cancer: A systematic review Management of cancer pain: ESMO Clinical Recommendations The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology Choosing between the EORTC QLQ-C30 and FACT-G for measuring health-related quality of life in cancer clinical research: issues, evidence and recommendations General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States The MOS 36-item short-form health survey (SF-36). key: cord-348570-plds5kbn authors: Buneviciene, Inesa; Mekary, Rania A.; Smith, Timothy R.; Onnela, Jukka-Pekka; Bunevicius, Adomas title: Can mHealth interventions improve quality of life of cancer patients? keywords: breast; cancer; control; group; hrqol; interventions; life; mhealth; patients; quality; studies; study cache: cord-348570-plds5kbn.txt plain text: cord-348570-plds5kbn.txt item: #427 of 449 id: cord-348841-qxkmngyk author: Kozakiewicz, Christopher P. title: Pathogens in space: Advancing understanding of pathogen dynamics and disease ecology through landscape genetics date: 2018-07-28 words: 7501 flesch: 20 summary: However, host landscape genetic studies can provide indications of the potential risk of spread of infectious agents, and the understanding gained about host movements can inform subsequent studies of pathogen dynamics. Our review emphasizes the expanding utility of landscape genetic methods available for elucidating key pathogen dynamics (particularly transmission and spread) and also how landscape genetic studies of pathogens can provide insight into host population dynamics. keywords: approaches; data; disease; et al; genetic; host; landscape; landscape genetics; pathogen; population; spread; structure; studies; study; transmission; vector cache: cord-348841-qxkmngyk.txt plain text: cord-348841-qxkmngyk.txt item: #428 of 449 id: cord-348994-ly2fop7d author: Faustini, Annunziata title: Attributable Risk to Assess the Health Impact of Air Pollution: Advances, Controversies, State of the Art and Future Needs date: 2020-06-23 words: 8164 flesch: 31 summary: 2. They can observe the same relationship under different circumstances, such as seasons, and in different populations thus making causality a more plausible interpretation of any possible association, providing that heterogeneity has been controlled for or assessed; 3. Even a weak effect of air pollution on health will constitute an important public health problem, since a unique characteristic of air pollution exposure is its ubiquity for large populations. The discussion began with Kunzli's observations [45] about the double action of air pollution on both the long-term underlying diseases and the short term risk of death: the author identified four different combinations: (a) air pollution increases the risks of both underlying diseases, leading to frailty, and of short-term mortality among the frail; (b) air pollution increases the risk of chronic diseases but is unrelated to the timing of death; (c) air pollution is unrelated to chronic diseases but short term exposure increases mortality among the frail; (d) neither underlying chronic disease nor death is related to air pollution exposure. keywords: air pollution; assessment; effects; exposure; health; health effects; impact; mortality; particulate; population; risk; studies; study; term; term exposure cache: cord-348994-ly2fop7d.txt plain text: cord-348994-ly2fop7d.txt item: #429 of 449 id: cord-349161-4899cq99 author: Whiting, Penny F title: Graphical presentation of diagnostic information date: 2008-04-11 words: 5811 flesch: 29 summary: The STARD (standards for reporting of diagnostic accuracy) statement, an initiative to improve the reporting of diagnostic test accuracy studies similar to the CONSORT statement for clinical trials, recommends the inclusion of a flow diagram in all reports of primary diagnostic accuracy studies [9] . However, their application to systematic reviews of diagnostic test accuracy studies is Example graphs for systematic review data Figure 2 Example graphs for systematic review data. keywords: accuracy; accuracy studies; diagnosis; displays; plots; results; reviews; roc; sensitivity; specificity; studies; study; test cache: cord-349161-4899cq99.txt plain text: cord-349161-4899cq99.txt item: #430 of 449 id: cord-349474-pprxwij6 author: Elshami, Wiam title: The radiology workforce’s response to the COVID-19 pandemic in the Middle East, North Africa and India date: 2020-09-23 words: 4718 flesch: 40 summary: Baseline chest x-ray showed a sensitivity of 69% in COVID-19 infection and imaging follow-up (54) ; chest CT has a limited but important role in the clinical management of COVID-19 patients (50) . The respondents reported experiences of work-related stress (42.9%), high COVID-19 fear score (83.3%) and anxiety (10%) during the study period. keywords: anxiety; covid-19; fear; health; pandemic; radiology; score; stress; study; work cache: cord-349474-pprxwij6.txt plain text: cord-349474-pprxwij6.txt item: #431 of 449 id: cord-350424-gwkxxkuu author: Cleland, Brice T. title: Feasibility and Safety of Transcranial Direct Current Stimulation in an Outpatient Rehabilitation Setting After Stroke date: 2020-10-09 words: 5421 flesch: 48 summary: Study participants noted mild to moderate side effects from tDCS, including tingling, itching, pinching, and fatigue. Surprisingly, despite the large number of tDCS studies conducted in the laboratory, there is a dearth of studies that have been done in a clinical setting. keywords: current; fatigue; participants; stimulation; stroke; study; tdcs cache: cord-350424-gwkxxkuu.txt plain text: cord-350424-gwkxxkuu.txt item: #432 of 449 id: cord-350565-mejd7blb author: Lewnard, Joseph A title: Emerging Challenges and Opportunities in Infectious Disease Epidemiology date: 2019-03-16 words: 6619 flesch: 10 summary: The impact of past vaccination coverage and immunity on pertussis resurgence Direct and indirect effects in vaccine efficacy and effectiveness Population biology of infectious diseases: Part I Population biology of infectious diseases: Part II Modeling infectious disease dynamics in the complex landscape of global health BEAST 2: a software platform for Bayesian evolutionary analysis Supersize me: how whole-genome sequencing and big data are transforming epidemiology The surveillance of communicable diseases of national importance Completeness of notifiable infectious disease reporting in the United States: an analytical literature review US Centers for Disease Control and Prevention and its partners' contributions to global health security Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study US Agency for International Development Uncovering Earth's virome The Global Virome Project Pandemics: spend on surveillance, not prediction Global trends in emerging infectious diseases Towards a genomics-informed, realtime, global pathogen surveillance system Ebola virus disease: 11,323 deaths later, how far have we come? Simulation-guided design further presents the opportunity for applying adaptive trial methods (115) in the context of infectious disease outbreaks, where dynamic trends in incidence may highlight the benefits of such approaches. keywords: data; disease; ebola; epidemiology; health; influenza; methods; models; pathogens; resistance; studies; surveillance; transmission; trial; vaccination; vaccine; virus cache: cord-350565-mejd7blb.txt plain text: cord-350565-mejd7blb.txt item: #433 of 449 id: cord-350571-6tapkjb6 author: None title: 45th ESCP-NSF international symposium on clinical pharmacy: clinical pharmacy tackling inequalities and access to health care. Oslo, Norway, 5–7 October 2016 date: 2017-01-10 words: 106086 flesch: 45 summary: Clinical pharmacists have a role to evaluate and optimize the appropriateness and effectiveness of patient's medications. DTSIs interventions (treatment group) consist in: motivational interview, sharing and delivery of printed, explanatory material in the patient's native language, reconciliation of patients medications at hospital admission and at discharge; identification of potential risks due to drug-drug interactions; monitoring of compliance to drug therapy, and finally detection of adverse drug reactions (ADRs) occurring in the course of care. keywords: abstract; adherence; administration; admission; age; aim; analysis; antibiotics; assessment; associated; average; background; cancer; care; cases; clinical; community; conclusion; control; criteria; data; day; days; department; design; discharge; discrepancies; disease; dispensing; dosage; dose; drug; effects; following; general; group; guidelines; health; home; hospital; hospital pharmacy; impact; increase; information; interactions; interventions; knowledge; level; main; management; mean; measures; median; medical; medication; medication adherence; medication reconciliation; medicines; method; monitoring; months; n =; non; number; nurses; objective; oral; order; outcome; outcome measures; patients; period; pharmaceutical; pharmacists; pharmacy; physicians; potential; practice; prescribed; prescription; problems; process; projects; quality; research; results; review; risk; risk patients; role; safety; score; service; setting; study; survey; team; therapy; time; total; treatment; type; university; use; years cache: cord-350571-6tapkjb6.txt plain text: cord-350571-6tapkjb6.txt item: #434 of 449 id: cord-351530-crsii3pu author: Zhao, Fuqiang title: Caring for the Caregiver during COVID-19 Outbreak: Does Inclusive Leadership Improve Psychological Safety and Curb Psychological Distress? A Cross-sectional Study date: 2020-07-30 words: 8989 flesch: 37 summary: This inclusive behaviour helps bring about a positive mood among employees and at the workplace in general (Hollander, 2009) which in turn, as a pleasant affective state, reduces the potential of employee psychological distress. Inclusive leadership has an inverse relationship with psychological distress with a strong path-coefficient. keywords: demands; distress; et al; healthcare; job; leadership; nurses; research; resources; role; safety; study; time; work cache: cord-351530-crsii3pu.txt plain text: cord-351530-crsii3pu.txt item: #435 of 449 id: cord-351734-wjvhu1qg author: Kassaw, Chalachew title: The Current Mental Health Crisis of COVID-19 Pandemic Among Communities Living in Gedeo Zone Dilla, SNNP, Ethiopia, April 2020 date: 2020-08-25 words: 1844 flesch: 59 summary: Mental health services have been working to address the crisis through online, outpatient, and inpatient mental health services for all of the communities in need [8] . Therefore, the purpose of this study was to determine the magnitude of mental health crisis and associated factors related to the pandemic. keywords: covid-19; crisis; health; pandemic; study cache: cord-351734-wjvhu1qg.txt plain text: cord-351734-wjvhu1qg.txt item: #436 of 449 id: cord-352040-zmkjine7 author: Dominski, Fábio Hech title: Psychological variables of CrossFit participants: a systematic review date: 2020-08-29 words: 6620 flesch: 34 summary: This scale was designed specifically for use in exercise training studies, and it uses a 15-point scale (5 points for study quality and 10 points for reporting). Kinesiology, Sport Studies, and Physical Education Synthesis Projects The role of social capital and community belongingness for exercise adherence: an exploratory study of the CrossFit gym model High-intensity functional training improves functional movement and body composition among cancer survivors: a pilot study The benefits and risks of the high-intensity CrossFit training The influence of sense of community on the perceived value of physical activity: a cross-context analysis The lived experience of CrossFit as a context for the development of women's body image and appearance management practices Physiological differences between advanced CrossFit athletes, recreational CrossFit participants, and physically-active adults Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement Checking reference lists to find additional studies for systematic reviews Utilization of the PICO framework to improve searching PubMed for clinical questions Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration Standards for reporting qualitative research: a synthesis of recommendations Validation of a new tool for the assessment of study quality and reporting in exercise training studies: TESTEX Attentive processes, blood lactate and CrossFit® The relationship between basic psychological need satisfaction, behavioral regulation, and Participation in CrossFit Motivational factors in CrossFit® training participation Examining the influence of CrossFit participation on body image, self-esteem, and eating behaviours among women Percepción de esfuerzo, diversión y aprendizaje en alumnos de educación secundaria en las clases de Educación Física durante una Unidad Didáctica de CrossFit. keywords: body; crossfit; exercise; health; intensity; mood; motivation; participants; practice; review; studies; study; training cache: cord-352040-zmkjine7.txt plain text: cord-352040-zmkjine7.txt item: #437 of 449 id: cord-352364-yj31uwiu author: El Morr, Christo title: Effectiveness of ICT-based intimate partner violence interventions: a systematic review date: 2020-09-07 words: 7306 flesch: 38 summary: The questions that guided us in examining the were as follows: (1) what type of objectives did ICT based interventions tried to address?, (2) were ICT based interventions effective in addressing IPV?, and (3) what type of strategies did they implement to mitigate ICT risks (e.g. safety, data security). Our review shows that 8 studies [55, 56, 59, 63, 64, 70, 72, 75] reported that women found ICT interventions suitable for IPV disclosure; three of those studies found it particularly suitable in terms of confidentiality, usefulness, and satisfaction [56, 63, 72] . keywords: address; health; ict; interventions; ipv; partner; review; safety; screening; studies; study; use; violence; web; women cache: cord-352364-yj31uwiu.txt plain text: cord-352364-yj31uwiu.txt item: #438 of 449 id: cord-352844-wggg3ynb author: Annunziata, Francesca title: An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities date: 2020-06-29 words: 51219 flesch: 38 summary: The resulting effect was expected to be a higher maximum collapse temperature and a faster synthesis of coumarin compounds by Knoevenagel reaction. The resulting effect was expected to be a higher maximum collapse temperature and a faster synthesis of coumarin compounds by Knoevenagel reaction. keywords: acid; activities; activity; antibacterial; antifungal; antioxidant activity; cancer; catalyst; cells; collaborators; complexes; compounds; coumarin; coumarin compounds; coumarin derivatives; detection; drug; effect; figure; fluorescent; group; human; ic50; inhibition; inhibitors; ions; novel; order; potential; probe; properties; reaction; reference; results; series; solvent; studies; synthesis; triazole; values; vitro; workers cache: cord-352844-wggg3ynb.txt plain text: cord-352844-wggg3ynb.txt item: #439 of 449 id: cord-352969-rpt7xja6 author: Kataria, Ashish title: COVID-19 in Kidney Transplantation: Epidemiology, Management Considerations, and the Impact on Kidney Transplant Practice date: 2020-07-15 words: 5980 flesch: 38 summary: 19 Reverse-transcription polymerase chain reaction (RT-PCR) assay of upper respiratory secretions usually collected with a nasopharyngeal swab is the current diagnostic test of choice for COVID-19 patients. COVID-19 patients have been reported to develop profound lymphopenia. keywords: coronavirus; covid-19; data; disease; kidney; ktrs; patients; population; recipients; sars; studies; study; transplant cache: cord-352969-rpt7xja6.txt plain text: cord-352969-rpt7xja6.txt item: #440 of 449 id: cord-353528-8a3f5hxu author: Levy, Oren title: Shattering barriers toward clinically meaningful MSC therapies date: 2020-07-22 words: 13111 flesch: 24 summary: Safety of cell therapy with mesenchymal stromal cells (SafeCell): A systematic review and meta-analysis of clinical trials Effective treatment of steroid and therapy-refractory acute graft-versushost disease with a novel mesenchymal stromal cell product (MSC-FFM) Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells Plasticity of mesenchymal stem cells in immunomodulation: K.S. has been a consultant for stem cell and oncology companies including Mesoblast, Cynata, and Merrimack. keywords: administration; bone; cells; disease; example; factors; homing; host; human; marrow; mesenchymal; mesenchymal stem; mscs; patients; phase; potency; site; stem; stem cells; stromal; studies; study; therapeutic; therapies; therapy cache: cord-353528-8a3f5hxu.txt plain text: cord-353528-8a3f5hxu.txt item: #441 of 449 id: cord-353787-24c98ug8 author: Jackson, J. A. title: Immunology in wild nonmodel rodents: an ecological context for studies of health and disease date: 2015-04-27 words: 8778 flesch: 17 summary: In scenarios where the aim is to identify emergent disease risks before any infectious agent is specifically identified, immune expression studies may provide a way to filter potential diseased amplifier individuals from natural populations and focus attention on these for further study. Early analyses in a partial cross-sectional data set for immune gene expression (2008) (2009) , and without considering pathogen data, suggested the value of the measurement approach through the existence of significant variation of expression in relation to season, life-history stage and individual condition (1) . keywords: animals; condition; expression; gata3; gene; immune; infection; laboratory; populations; responses; rodents; species; studies; study; system; tolerance; variation; wild cache: cord-353787-24c98ug8.txt plain text: cord-353787-24c98ug8.txt item: #442 of 449 id: cord-353876-pb4of7s9 author: Fortaleza, Carlos Magno Castelo Branco title: Evidence, rationality, and ignorance: Agnotological issues in COVID-19 science date: 2020-09-21 words: 3263 flesch: 38 summary: This serves as a fertile breeding ground for agnotological strategies, whereby scientific studies are deliberately or unintentionally designed to create distractions or draw conclusions that are not supported by research findings. Researchers, public health authorities, and healthcare workers should be equipped to identify such agnotological strategies, distinguish them from scientific fraud, and avoid drawing misleading inferences based on an irrational adherence to hypotheses and a lack of criticism of implausible results. keywords: covid-19; evidence; findings; ignorance; research; science; strategies; studies cache: cord-353876-pb4of7s9.txt plain text: cord-353876-pb4of7s9.txt item: #443 of 449 id: cord-354216-4khdcjed author: Sultan, Shahnaz title: AGA Institute Rapid Review of the GI and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19 date: 2020-05-11 words: 5643 flesch: 38 summary: Therefore, in high prevalence settings, among patients presenting with new onset diarrhea, monitoring for the development of COVID-19 symptoms and considering referring patients for COVIDtesting is reasonable especially if testing capacity is not limited. In a handful of studies, diarrhea and nausea preceded the development of other COVID-19 related symptoms. keywords: analysis; clinical; coronavirus; covid-19; data; diarrhea; disease; liver; patients; studies; symptoms cache: cord-354216-4khdcjed.txt plain text: cord-354216-4khdcjed.txt item: #444 of 449 id: cord-354306-zbkgabl2 author: Pennycook, Gordon title: Fighting COVID-19 Misinformation on Social Media: Experimental Evidence for a Scalable Accuracy-Nudge Intervention date: 2020-06-30 words: 5998 flesch: 44 summary: In particular, CRT score was negatively correlated with belief in false headlines and uncorrelated with belief in true headlines, whereas CRT score was negatively correlated with sharing of both types of headlines (albeit more negatively correlated with sharing of false headlines compared with true headlines; for effect sizes, see Table 1 ). In particular, science knowledge was negatively correlated with belief in false headlines and positively correlated with belief in true headlines, whereas science knowledge was negatively correlated with sharing of false headlines and uncorrelated with sharing of true headlines (for effect sizes, see Table 1 ). keywords: accuracy; covid-19; discernment; headlines; media; news; participants; sharing; study cache: cord-354306-zbkgabl2.txt plain text: cord-354306-zbkgabl2.txt item: #445 of 449 id: cord-354491-23cjm86c author: Muller, A. E. title: The mental health impact of the covid-19 pandemic onhealthcare workers, and interventions to help them: a rapid systematic review date: 2020-07-04 words: 7865 flesch: 41 summary: The studies reported on healthcare workers working in different settings: 43 studies reported on health care workers in hospitals, two studies were conducted in specialist health services outside hospitals, and three studies in other settings, while 21 studies did not specify the healthcare setting or only partially described multiple settings. The copyright holder for this preprint (which this version posted The impact of the covid-19 pandemic on mental health of health care workers: protocol for a rapid systematic review A systematic and living evidence map on COVID-19 AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both CASP checklist for qualitative research GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables Addressing Faculty Emotional Responses During the COVID19 Pandemic Anxiety and Depression Survey of Chinese Medical Staff Before and During COVID-19 Defense Assessment of Iranian nurses′ knowledge and anxiety toward COVID-19 during the current outbreak in Iran Assessment of the Mental Health of Front Line Healthcare Workers in a COVID-19 Epidemic Epicenter of China At the height of the storm: Healthcare staff's health conditions and job satisfaction and their associated predictors during the epidemic peak of COVID-19 Brief Psychotic Disorder Triggered by Fear of Coronavirus? Comparison of the Indicators of Psychological Stress in the Population of Hubei Province and Non-Endemic Provinces in China During Two Weeks During the Coronavirus Disease 2019 (COVID-19) Outbreak in February 2020 COVID19 pandemic impacts on anxiety of French urologist in training: Outcomes from a national survey COVID-19 and mental health: A review of the existing literature COVID-19 and paediatric health services: A survey of paediatric physicians in Australia and New Zealand COVID-19 associated psychiatric symptoms in healthcare workers: viewpoint from internal medicine and psychiatry residents COVID-19 outbreak situation and its psychological impact among surgeon in training in France COVID-19-Related Information Sources and Psychological Well-being: An Online Survey Study in Taiwan A cross-sectional study on mental health among health care workers during the outbreak of Corona Virus Disease The Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease 2019 (COVID-19) in January and February 2020 in China Emergency Responses to COVID-19 Outbreak: Experiences and Lessons from a General Hospital in Nanjing Evaluation of the Level of Anxiety among Iranian Multiple Sclerosis Fellowships During the Outbreak of COVID-19 Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak The immediate mental health impacts of the COVID-19 pandemic among people with or without quarantine managements The Impact of COVID-19 Pandemic on Spine Surgeons Worldwide Impact on mental health and perceptions of psychological care among medical and nursing staff in Wuhan during the 2019 novel coronavirus disease outbreak: A cross-sectional study Investigation and analysis of the psychological status of the clinical nurses in a class A hospital facing the novel coronavirus pneumonia Issues relevant to mental health promotion in frontline health care providers managing quarantined/isolated COVID19 patients Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China Mental health care for medical staff in China during the COVID-19 outbreak. keywords: author; covid-19; healthcare; license; medrxiv; mental; pandemic; preprint; psychological; review; studies; study; workers cache: cord-354491-23cjm86c.txt plain text: cord-354491-23cjm86c.txt item: #446 of 449 id: cord-354592-vqws942c author: Cauvin, Annick J. title: Advantages and Limitations of Commonly Used Nonhuman Primate Species in Research and Development of Biopharmaceuticals date: 2015-03-20 words: 7301 flesch: 29 summary: Such findings could not have been observed in mice, whose physiology of parturition is very different, or in monkey studies not specifically addressing parturition, but they highlight a risk for pregnant women still exposed to the mAb by the end of the pregnancy based on the similar physiology of pregnancy and parturition in NHPs and humans. Especially for studies of sex hormones, synthetic steroidal compounds, or compounds that interfere with the hypothalamus-pituitary-ovarian (or testicular) axis, such monkey species are predictive [30] . keywords: assessment; cynomolgus; development; differences; humans; macaques; marmosets; monkeys; nhp; nhps; reproductive; rhesus; species; studies; target; toxicology cache: cord-354592-vqws942c.txt plain text: cord-354592-vqws942c.txt item: #447 of 449 id: cord-355038-o2hr5mox author: None title: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date: 2020-02-11 words: 102622 flesch: 49 summary: No significant difference between the NE and AVP groups for lactate clearance between H0 and H6 (25.6 [− 7.31 to 35.34]% vs 47.84 [13.42-82.73 ]%, p = 0.686). D: blood frequency of MAIT cells in patients with pneumonia compared with healthy controls (as % of total T cells) keywords: 0.001; acute; admission; adult patients; age; aim; aki; analysis; antibiotic; ards; ards patients; association; blood; cardiac; care; care patients; care unit; cases; characteristics; children; cohort; compliance; complications; conclusion; conflict; control; data; days; death; diagnosis; disclosure; disease; duration; dysfunction; early; ecmo; end; ethics regulations; factors; failure; fig; following; france; group; high; hospital; hospital mortality; icu admission; icu mortality; icu patients; icu stay; impact; incidence; infection; influenza patients; injury; intensive; intensive care; interest; international; intubation; january; length; management; mean; median; medical; methods; model; months; mortality; mortality rate; multivariate; n =; national; niv; non; objective; outcome; p =; patients; period; pneumonia; post; pressure; prognosis; pulmonary; rate; rationale; respiratory; results; risk; score; sepsis; septic; severity; shock; sofa; stay; studies; study; study period; support; survival; syndrome; therapy; time; total; treatment; unit; use; ventilation; weaning; years cache: cord-355038-o2hr5mox.txt plain text: cord-355038-o2hr5mox.txt item: #448 of 449 id: cord-355318-qm79gz8w author: Smit, Albertus J. title: Winter Is Coming: A Southern Hemisphere Perspective of the Environmental Drivers of SARS-CoV-2 and the Potential Seasonality of COVID-19 date: 2020-08-05 words: 15421 flesch: 37 summary: A systematic review and meta-analysis Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-Infected men in South Africa Tuberculosis in sub-Saharan Africa: Opportunities, challenges, and change in the era of antiretroviral treatment Burden of HIV-associated histoplasmosis compared with tuberculosis in Latin America: A modelling study COVID-19 in HIV Investigators COVID-19 in patients with HIV: Clinical case series Maintaining HIV care during the COVID-19 pandemic Impact of COVID-19 on tuberculosis control in China COVID-19: Getting ahead of the epidemic curve by early implementation of social distancing Viral dynamics in mild and severe cases of COVID-19 Report from the American Society for Microbiology COVID-19 International Summit Delivery of infection from asymptomatic carriers of COVID-19 in a familial cluster Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals COVID-19: A need for real-time monitoring of weekly excess deaths No association of COVID-19 transmission with temperature or UV radiation in Chinese cities Impact of weather on COVID-19 pandemic in Turkey Association between ambient temperature and COVID-19 infection in 122 cities from China Modeling infectious disease dynamics in the complex landscape of global health Rt COVID-19 Renormalization group approach to pandemics: The COVID-19 case. Revista Ibero-Americana de Ciências Ambientias 2020 Gaussian approach for probability and correlation between the number of COVID-19 cases and the air pollution in Lima The role of climate during the COVID-19 epidemic in New South Wales Correlation between climate indicators and COVID-19 pandemic Correlation between weather and Covid-19 pandemic in Jakarta Effect of weather on COVID-19 spread in the US: A prediction model for India in 2020 Impact of meteorological factors on the COVID-19 transmission: A multi-city study in China The role of environmental factors on transmission rates of the COVID-19 Outbreak: An initial assessment in two spatial scales The ERA-interim reanalysis: Configuration and performance of the data assimilation system The sensitivity and specificity analyses of ambient temperature and population size on the transmission rate of the novel coronavirus (COVID-19) in different provinces in Iran Non-linear modulation of COVID-19 transmission by climate conditions Transmissibility of COVID-19 and its association with temperature and humidity Developing a machine learning framework to determine the spread of COVID-19. keywords: air; cases; countries; cov-2; covid-19; data; disease; hemisphere; humidity; infection; influenza; models; pandemic; rate; sars; seasonality; spread; studies; temperature; time; transmission; variables; virus cache: cord-355318-qm79gz8w.txt plain text: cord-355318-qm79gz8w.txt item: #449 of 449 id: cord-356116-c40e3zp7 author: Savory, Eric title: Western Cold and Flu (WeCoF) aerosol study – preliminary results date: 2014-08-23 words: 5738 flesch: 44 summary: Although cough droplet sizes have been characterized, more research is needed to examine cough flows from infected individuals. [49] found no significant difference in maximum cough velocity related to sex and weight of the cougher. keywords: chamber; cough; droplets; field; flow; influenza; particles; size; study; transmission; velocity; virus cache: cord-356116-c40e3zp7.txt plain text: cord-356116-c40e3zp7.txt