# bib

id: cord-257641-wmbgpnr9
author: Katsarou, Maria
title: Acute Retrograde Type A Intramural Hematoma during SARS-CoV-2 time
date: 2020-10-15
extension: .txt
mime: text/plain
words: 493
sentence: 23
flesch: 52
cache: cache/cord-257641-wmbgpnr9.txt
txt: txt/cord-257641-wmbgpnr9.txt
summary:
  4 Medical treatment appears to be appropriate in asymptomatic patients, in those 1 with non-complicated retro-TAIMH and in patients with high open surgical / TEVAR risks. Therapeutic implications Management of retrograde type A IMH with acute arch tear/type B dissection Diagnosis and management of patients with aortic dissection


id: cord-031922-3pfxrhbc
author: Petrie, John R
title: SGLT2 inhibitors and renal complications in type 1 diabetes
date: 2020-09-15
extension: .txt
mime: text/plain
words: 1560
sentence: 49
flesch: 40
cache: cache/cord-031922-3pfxrhbc.txt
txt: txt/cord-031922-3pfxrhbc.txt
summary:
  key: cord-031922-3pfxrhbc authors: Petrie, John R title: SGLT2 inhibitors and renal complications in type 1 diabetes date: 2020-09-15 journal: Lancet Diabetes Endocrinol DOI: 10.1016/s2213-8587(20)30311-9 sha: doc_id: 31922 cord_uid: 3pfxrhbc nan Adding in non-insulin agents is one of several promising strategies under investigation to improve glycaemic control in type 1 diabetes. 2 Of several drug classes repurposed from type 2 to type 1 diabetes, SGLT2 inhibitors have made the most progress.


id: cord-030631-cc79j9j4
author: Marcus, Benjamin A.
title: Typ-1-Diabetes: Früherkennung und Ansätze zur Prävention: Update 2020
date: 2020-08-19
extension: .txt
mime: text/plain
words: 2249
sentence: 109
flesch: 38
cache: cache/cord-030631-cc79j9j4.txt
txt: txt/cord-030631-cc79j9j4.txt
summary:
  Die Ergebnisse dieser Untersuchung, die für mehr als die Hälfte der Behandelten eine Verdoppelung der Zeit bis Auch wenn derzeit noch nur davon ausgegangen werden sollte, dass sich für die behandelten Patienten der Beginn der Erkrankung weiter in die Zukunft verschiebt und der Effekt bei einer dauerhaft therapiebedürftigen Erkrankung moderat erscheinen mag, wirkt sich gerade bei Kindern jedes gewonnene klinisch gesunde Jahr noch weit mehr aus als im Erwachsenenalter.


id: cord-028840-7n77vko9
author: Chardonnet, Kostia
title: Toward a Curry-Howard Equivalence for Linear, Reversible Computation: Work-in-Progress
date: 2020-06-17
extension: .txt
mime: text/plain
words: 2632
sentence: 129
flesch: 62
cache: cache/cord-028840-7n77vko9.txt
txt: txt/cord-028840-7n77vko9.txt
summary:
  An iso ω : A ↔ B corresponds to both a computation sending a value of type A to a result of type B and a computation sending a value of type B to a result of type A. We can mechanically translate such an iso to a pair of derivations π, π ⊥ in , where π is a proof of A B and π ⊥ is a proof of B A. If ω is of type A ↔ B then inv ω is of type B ↔ A.


id: cord-008700-knbf8m4x
author: Rodrigues, Merlyn R.
title: Methods for Rapid Detection of Human Ocular Viral Infections
date: 2013-10-30
extension: .txt
mime: text/plain
words: 3016
sentence: 138
flesch: 33
cache: cache/cord-008700-knbf8m4x.txt
txt: txt/cord-008700-knbf8m4x.txt
summary:
  I Preparative procedures for examining icosahedral and filamentous viruses Two-hour embedding procedure for intracellular detection of viruses by electron microscopy Rapid Virus Diagnosis Application of Immunofluorescence Adenoviruses Rapid diagnosis of herpes virus hominis infections by immunofluorescent antibody techniques Community and hospital outbreaks of epidemic keratoconjunctivitis Simultaneous nosocomial and community outbreak of epidemic keratoconjunctivitis with types 8 and 19 adenovirus Epidemic keratoconjunctivitis at a Vietnamese refugee camp in Florida Adenovirus type 8 infections in the United States Potter MH: Epidemic keratoconjunctivitis due to adenovirus type 19 Epidemic keratoconjunctivitis and chronic papillary conjunctivitis in London due to adenovirus type 19 Epidemic adenovirus keratoconjunctivis Cytologic diagnosis of adenoviral epidemic keratoconjunctivitis by direct immunofluorescence The demonstration of Toxoplasma and other organisms by immunofluorescence: A pitfall Electron microscopy as a diagnostic procedure for viral infections of the eye. The positive serum had a titer of 1:640, and the negative serum, a titer of less than 1:10, by HAL These sera were then used in an indirect immunofluorescence test on rubella-infected and uninfected BHK-cells, a susceptible line used for laboratory propagation of rubella virus.


id: cord-292908-rbn3foj3
author: Hohdatsu, T.
date: 1991-06-30
extension: .txt
mime: text/plain
words: 3257
sentence: 129
flesch: 53
cache: cache/cord-292908-rbn3foj3.txt
txt: txt/cord-292908-rbn3foj3.txt
title:
  Antigenic analysis of feline coronaviruses with monoclonal antibodies (MAbs): Preparation of MAbs which discriminate between FIPV strain 79-1146 and FECV strain 79-1683

summary:
  Similarly, among the MAbs in Group V, which react with FIPV Type II viruses alone, F6-3 reacted with CCV, and F24-1 and F49-1 reacted with the SH strain of TGEV. However, MAbs in Group V reacted with FIPV Type II viruses alone, while MAbs in Group VI reacted with the 79-1683 strain of FECV Type II alone.


id: cord-026548-z2ifu1d6
author: Lagaillardie, Nicolas
title: Implementing Multiparty Session Types in Rust
date: 2020-05-13
extension: .txt
mime: text/plain
words: 3294
sentence: 170
flesch: 57
cache: cache/cord-026548-z2ifu1d6.txt
txt: txt/cord-026548-z2ifu1d6.txt
summary:
  Distributed programming using role parametric session types in Go Multiparty compatibility in communicating automata: characterisation and synthesis of global session types Exceptional asynchronous session types: session types without tiers Language primitives and type discipline for structured communication-based programming Multiparty asynchronous session types Hybrid session verification through endpoint API generation MQTT-S-a publish/subscribe protocol for wireless sensor networks Session types for Rust Rusty variation: deadlock-free sessions with failure in Rust Typechecking protocols with Mungo and StMungo Verifying asynchronous interactions via communicating session automata Session types for Rust A linear decomposition of multiparty sessions for safe distributed programming Less is more: multiparty session types revisited The Rust Programming Language. We extend an existing library for binary session types to MPST.


id: cord-010657-5qtsj8xv
author: Heckman, Carol A.
title: Pathogenesis of Lesions Induced in Rat Lung by Chronic Tobacco Smoke Inhalation
date: 1982-07-01
extension: .txt
mime: text/plain
words: 4332
sentence: 220
flesch: 44
cache: cache/cord-010657-5qtsj8xv.txt
txt: txt/cord-010657-5qtsj8xv.txt
summary:
  Type II hyperplastic lesions were observed most frequently at the pleura (figs. The cellular and extracellular constituents involved in enlargement of the interstitium in type II hyperplastic lesions were similar to those described in the preceding section.


id: cord-299756-m0va36er
author: Raaben, Matthijs
date: 2009-08-03
extension: .txt
mime: text/plain
words: 4573
sentence: 200
flesch: 49
cache: cache/cord-299756-m0va36er.txt
txt: txt/cord-299756-m0va36er.txt
title:
  Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo

summary:
  To confirm and extend these observations, we next analyzed the induction of type I and II IFN gene expression (i.e. IFN-α4 and IFN-β1, and IFN-γ, respectively) by using quantitative RT-PCR. In contrast, in the 129SvEv mice, no significant induction of gene expression was observed.


id: cord-001124-qcjbtflt
author: Carrero, Javier Antonio
title: Confounding roles for type I interferons during bacterial and viral pathogenesis
date: 2013-10-24
extension: .txt
mime: text/plain
words: 4555
sentence: 179
flesch: 33
cache: cache/cord-001124-qcjbtflt.txt
txt: txt/cord-001124-qcjbtflt.txt
summary:
  in murine listeriosis TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages Lymphocyte apoptosis during early phase of Listeria infection in mice Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice Mechanisms and immunological effects of apoptosis caused by Listeria monocytogenes Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice HIV-1 immunopathogenesis: how good interferon turns bad How do viral infections predispose patients to bacterial infections? In the case of LCMV, chronic IFN-I signaling induces adaptive immune system suppression.


id: cord-284514-b7no0yrv
author: Davies, Robert L
date: 2003-02-02
extension: .txt
mime: text/plain
words: 4652
sentence: 149
flesch: 39
cache: cache/cord-284514-b7no0yrv.txt
txt: txt/cord-284514-b7no0yrv.txt
title:
  Diversity of avian Pasteurella multocida strains based on capsular PCR typing and variation of the OmpA and OmpH outer membrane proteins

summary:
  Clonal analysis of descent and virulence among selected Escherichia coli Six widespread bacterial clones among Escherichia coli K1 isolates Major heat-modifiable outer membrane protein in gram-negative bacteria: comparison with the OmpA protein of Escherichia coli Immunologic response to turkey poults of various ages to an avirulent Pasteurella multocida vaccine in the drinking water Characterisation of Pasteurella multocida isolated from fowl cholera outbreaks on turkey farms Population structure and diversity of avian isolates of Pasteurella multocida from Australia Molecular epidemiology of Pasteurella multocida in turkeys Identification of type D Pasteurella multocida by counterimmunoelectrophoresis Transmission of Pasteurella multocida on California turkey premises in 1988-1989 Intra-specific diversity and host specificity within Pasteurella haemolytica based on variation of capsular polysaccharide, lipopolysaccharide and outer-membrane proteins Outer membrane protein and lipopolysaccharide variation in Pasteurella haemolytica A1 under different growth conditions Evolutionary genetics of Pasteurella haemolytica isolates recovered from cattle and sheep Molecular variation in the major outer membrane protein P5 gene of nonencapsulated Haemophilus influenzae during chronic infections Random amplification of polymorphic DNA and phenotypic typing of Zimbabwean isolates of Pasteurella multocida Phenotypic characterisation of Pasteurella multocida isolates from Australian poultry Variation in length and sequence of porin (ompP2) alleles of non-capsulate Haemophilus influenzae Molecular characterisation of avian Pasteurella multocida isolates from Australia and Vietnam by REP-PCR and PFGE Bacterial outer membranes: evolving concepts Serum resistance is correlated with encapsulation of avian strains of Pasteurella multocida Characteristics of Pasteurella multocida isolated from waterfowl and associated avian species in California Outer membrane protein patterns mark clones of Escherichia coli O2 and O78 strains that cause avian septicemia Pasteurella multocida produces a protein with homology to the P6 outer membrane protein of Haemophilus influenzae Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Cloning and characterization of the major outer membrane protein gene (ompH) of Pasteurella multocida X-73 Sequence analysis of Pasteurella multocida major outer membrane protein (OmpH) and application of synthetic peptides in vaccination of chickens against homologous strain challenge A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples A population genetic framework for the study of invasive diseases caused by serotype b strains of Haemophilus influenzae Clonal population structure of encapsulated Haemophilus influenzae Reclassification of the genus Pasteurella Trevisan 1887 on the basis of deoxyribonucleic acid homology, with proposals for the new species Pasteurella dagmatis, Pasteurella canis, Pasteurella stomatis, Pasteurella anatis, and Pasteurella langaa Antibodies to loop 6 of the P2 porin protein of nontypeable Haemophilus influenzae are bactericidal against multiple strains Genetic diversity of Pasteurella multocida fowl cholera isolates as demonstrated by ribotyping and 16S rRNA and partial atpD sequence comparisons The pathogenesis of Pasteurella multocida serotype A:3,4 infection in turkeys: a comparison of two vaccine strains and a field isolate Capsular groups of Pasteurella multocida isolated from avian hosts Virulence of avian capsular serogroup B Pasteurella multocida for turkey poults Fowl cholera Somatic serotypes of Pasteurella multocida strains isolated from avian hosts (1976-1988) Virulence and toxigenicity of capsular serogroup D Pasteurella multocida strains isolated from avian hosts Fowl cholera Serogroup F, a new capsule serogroup of Pasteurella multocida Pasteurella multocida Characterization of the major envelope protein from Escherichia coli. This PCR-based capsular typing method was used in the present study and found to be a reliable and rapid method for capsular typing large numbers of P. multocida isolates.


id: cord-259935-xyo2pe4g
author: Wang, Ching-Ying
date: 2017-05-02
extension: .txt
mime: text/plain
words: 4679
sentence: 159
flesch: 41
cache: cache/cord-259935-xyo2pe4g.txt
txt: txt/cord-259935-xyo2pe4g.txt
title:
  SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling

summary:
  The expression of SARS-PLpro in lung tissues of mice was determined using IHC staining with anti-E. coli synthesized PLpro serum, and IHC positivity for PLpro expression within lung tissues was observed in the group infected with pSARS-PLpro ( Fig. 2A) . PLpro expression caused the STAT6 expression and induced the translation of STAT6 in the nucleus.


id: cord-015503-j99cgsjt
author: Tang, Xiaolu
title: On the origin and continuing evolution of SARS-CoV-2
date: 2020-03-03
extension: .txt
mime: text/plain
words: 5255
sentence: 212
flesch: 52
cache: cache/cord-015503-j99cgsjt.txt
txt: txt/cord-015503-j99cgsjt.txt
summary:
  Our results suggest that the development of new variations in functional sites in the receptor-binding domain (RBD) of the spike seen in SARS-CoV-2 and viruses from pangolin SARSr-CoVs are likely caused by mutations and natural selection besides recombination. For each annotated ORF in the reference genome of SARS-CoV-2 (NC_045512), we extracted the orthologous sequences in human SARS-CoV, four bat SARS-related coronaviruses (SARSr-CoV: RaTG13, ZXC21, ZC45, and BM48-31), one Pangolin SARSr-CoV from Guangdong (GD)


id: cord-292344-3bj567gr
author: Zimmet, P.
title: The burden of type 2 diabetes: are we doing enough?
date: 2003-09-30
extension: .txt
mime: text/plain
words: 5322
sentence: 210
flesch: 45
cache: cache/cord-292344-3bj567gr.txt
txt: txt/cord-292344-3bj567gr.txt
summary:
  Diabetes Care The changing demography of diabetes mellitus in Singapore Epidemiologic study of type 2 diabetes in Taiwan WHO Ad Hoc Diabetes Reporting Group: global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults Diabetes trends in Latin America Diabetes trends in Africa Diabetes trends in the US: 1990-1998 Visceral obesity and metabolic syndrome Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study Pathogenesis of NIDDM. The cost of diabetes mellitus and its impact on health spending in Mexico The projected health care burden of type 2 diabetes in the UK from Cost-effectiveness of intensive lifestyle changes or metformin in overweight, glucose-intolerant patients: modelling the long-term implications of the diabetes prevention Program in the French, German and UK settings Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program Descriptive epidemiology of non-insulin dependent diabetes mellitus detected by urine glucose screening in school children in Japan US public health and the 21 st century: diabetes mellitus The diabetes risk score: a practical tool to predict type 2 diabetes DEHKO: Development programme for the prevention and care of diabetes in Finland


id: cord-284608-ba7wq52t
author: Sias, Catia
date: 2019-03-04
extension: .txt
mime: text/plain
words: 5652
sentence: 237
flesch: 51
cache: cache/cord-284608-ba7wq52t.txt
txt: txt/cord-284608-ba7wq52t.txt
title:
  Alpha, Beta, gamma human PapillomaViruses (HPV) detection with a different sets of primers in oropharyngeal swabs, anal and cervical samples

summary:
  Currently, there are no guidelines recommending HPV oral cavity screening as a mandatory test, and it remains unknown which HPV types should be included in HPV screening programs. In addition, it remains unknown which HPV types should be included in oral cavity screening.


id: cord-262545-bs8p50ig
author: Luk, Andrea O. Y.
date: 2020-02-20
extension: .txt
mime: text/plain
words: 6137
sentence: 234
flesch: 54
cache: cache/cord-262545-bs8p50ig.txt
txt: txt/cord-262545-bs8p50ig.txt
title:
  Secular trends in incidence of type 1 and type 2 diabetes in Hong Kong: A retrospective cohort study

summary:
  However, diabetes types were not differentiated, and trends among the paediatric population were not explored. The separation of diabetes types is not reliable based on coding alone in administrative databases.


id: cord-266488-wc6k06sm
author: Feng, Mingqian
date: 2018-11-07
extension: .txt
mime: text/plain
words: 6578
sentence: 286
flesch: 53
cache: cache/cord-266488-wc6k06sm.txt
txt: txt/cord-266488-wc6k06sm.txt
title:
  Construction and next-generation sequencing analysis of a large phage-displayed V(NAR) single-domain antibody library from six naïve nurse sharks

summary:
  To construct a large shark V NAR library, we developed a method called EASeL. As illustrated in Figure 1A , we isolated peripheral blood leukocytes from six adult nurse sharks (G. cirratum) and amplified shark V NAR sequences with PCR primers. The library contains all types (I-IV) of shark V NAR sequences as well as many other previously undefined types.


id: cord-314328-gft6phd6
author: Lawrence, C.
date: 2020-10-23
extension: .txt
mime: text/plain
words: 2092
sentence: 85
flesch: 47
cache: cache/cord-314328-gft6phd6.txt
txt: txt/cord-314328-gft6phd6.txt
title:
  Increased paediatric presentations of severe diabetic ketoacidosis in an Australian tertiary centre during the COVID‐19 pandemic

summary:
  key: cord-314328-gft6phd6 authors: Lawrence, C.; Seckold, R.; Smart, C.; King, B. R.; Howley, P.; Feltrin, R.; Smith, T. A.; Roy, R.; Lopez, P. title: Increased paediatric presentations of severe diabetic ketoacidosis in an Australian tertiary centre during the COVID‐19 pandemic date: 2020-10-23 journal: To determine if the frequency of severe diabetic ketoacidosis at presentation of new‐onset type 1 diabetes to an Australian tertiary centre increased during the initial period of restrictions resulting from the COVID‐19 pandemic (March to May 2020).


id: cord-240471-rz0pj5a3
author: Dodds, P. S.
date: 2020-08-30
extension: .txt
mime: text/plain
words: 7203
sentence: 324
flesch: 54
cache: cache/cord-240471-rz0pj5a3.txt
txt: txt/cord-240471-rz0pj5a3.txt
title:
  Probability-turbulence divergence: A tunable allotaxonometric instrument for comparing heavy-tailed categorical distributions

summary:
  For the comparison of type frequency distributions of two systems or a system with itself at different time points in time -- a facet of allotaxonometry -- a great range of probability divergences are available. On Gitlab, we provide our universal code for generating allotaxonographs for rank-turbulence divergence, probability-turbulence divergence, and other probability divergences (see Sec.


id: cord-269734-u43gt8fh
author: Teijaro, J.R.
title: Pleiotropic Roles of Type 1 Interferons in Antiviral Immune Responses
date: 2016-09-20
extension: .txt
mime: text/plain
words: 7471
sentence: 209
flesch: 16
cache: cache/cord-269734-u43gt8fh.txt
txt: txt/cord-269734-u43gt8fh.txt
summary:
  Moreover, exogenous administration of IL-10 to IFNAR1-deficient animals following influenza virus infection partially restored survival and ameliorated lung pathology. Thus, IFN-I can be protective during influenza virus infection either through suppressing virus spread or prompting induction of immune-suppressive cytokines to reign in excessive inflammation.


id: cord-293819-tbdsr5iw
author: Carvalho, C.L.
title: Tularaemia: A challenging zoonosis
date: 2014-01-13
extension: .txt
mime: text/plain
words: 7830
sentence: 362
flesch: 38
cache: cache/cord-293819-tbdsr5iw.txt
txt: txt/cord-293819-tbdsr5iw.txt
summary:
  Natural infections with F. tularensis have also been documented in different arthropods, although only a subset of these have been identified as important in F. tularensis transmission to humans. Also, a renewed concern has arisen with regard to F. tularensis: its potential use by bioterrorists.


id: cord-103108-vmze2mdx
author: Vanheer, Lotte
title: Revealing the Key Regulators of Cell Identity in the Human Adult Pancreas
date: 2020-09-25
extension: .txt
mime: text/plain
words: 7974
sentence: 225
flesch: 29
cache: cache/cord-103108-vmze2mdx.txt
txt: txt/cord-103108-vmze2mdx.txt
summary:
  We show that a network of 142 transcription factors forms distinct regulatory modules that characterize pancreatic cell types. We next sought to identify pancreatic cell types ( Figure 1D ).


id: cord-001273-plz1ja2e
author: Dussurget, Olivier
date: 2014-04-28
extension: .txt
mime: text/plain
words: 7429
sentence: 226
flesch: 31
cache: cache/cord-001273-plz1ja2e.txt
txt: txt/cord-001273-plz1ja2e.txt
title:
  The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons

summary:
  The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-lambda family Listeria monocytogenesfrom saprophyte to intracellular pathogen Gastrointestinal phase of Listeria monocytogenes infection Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection Recent developments in the transcriptional regulation of cytolytic effector cells Control points in NKT-cell development The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the IκB kinase subunit IKKα Incidence of listeriosis and related mortality among groups at risk of acquiring listeriosis RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells Importance of murine The role of the activated macrophage in clearing Listeria monocytogenes infection IL-28, IL-29 and their class II cytokine receptor IL-28R Monocyte recruitment during infection and inflammation Nuclear receptor ERR-alpha and coactivator PGC-1beta are effectors of IFN-gamma-induced host defense Cell biology and immunology of Listeria monocytogenes infections: novel insights Type I interferons in host defense Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR-and Nod2-independent mechanism Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type


id: cord-321878-bnjupaik
author: Deliwala, Smit S.
date: 2020-07-23
extension: .txt
mime: text/plain
words: 2254
sentence: 90
flesch: 38
cache: cache/cord-321878-bnjupaik.txt
txt: txt/cord-321878-bnjupaik.txt
title:
  A 29-Year-Old Male with a Fatal Case of COVID-19 Acute Respiratory Distress Syndrome (CARDS) and Ventilator-Induced Lung Injury (VILI)

summary:
  COVID-19 patients complicated by ARDS (CARDS) can present despite lacking traditional risk factors such as advancing age, pre-existing co-morbidities, or an advanced lung pathology [5] . Post-mortem studies reveal numerous thromboses in COVID-19 patients with d-dimer serving as a surrogate marker of pulmonary endothelial damage, promoting ventilation-perfusion mismatches and subsequent hypoxemia


id: cord-307128-wwjeu8ie
author: Walz, Lucas
date: 2020-08-11
extension: .txt
mime: text/plain
words: 4396
sentence: 198
flesch: 39
cache: cache/cord-307128-wwjeu8ie.txt
txt: txt/cord-307128-wwjeu8ie.txt
title:
  Janus Kinase-Inhibitor and Type I Interferon Ability to Produce Favorable Clinical Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis

summary:
  medRxiv preprint studies complied with the inclusion criteria. Figure 1 presents the meta-analysis flow chart and Table 1 presents the designs and characteristics of included studies.


id: cord-332133-6hdk8801
author: Li, Mao-Zhong
title: A Pneumonia Case Associated with Type 2 Polio Vaccine Strains
date: 2017-01-05
extension: .txt
mime: text/plain
words: 1232
sentence: 49
flesch: 46
cache: cache/cord-332133-6hdk8801.txt
txt: txt/cord-332133-6hdk8801.txt
summary:
  The global introduction of inactivated polio vaccine Investigations of clinical isolations of oral poliovirus vaccine strains between 2000 and 2005 in Southern Taiwan Genotyping of enteroviruses isolated in Kenya from pediatric patients using partial VP1 region Non-rhinovirus enteroviruses associated with respiratory infections in Peru (2005-2010) He was hospitalized in the Capital Institute of Pediatrics with pneumonia on June 31, which was 27 days after taking the first tOPV, and he had similar respiratory clinical symptoms within 35 days after his second dose of tOPV.


id: cord-309795-2kozsv4z
author: Dewidar, Bedair
title: Metabolic liver disease in diabetes – from mechanisms to clinical trials
date: 2020-06-20
extension: .txt
mime: text/plain
words: 8655
sentence: 306
flesch: 28
cache: cache/cord-309795-2kozsv4z.txt
txt: txt/cord-309795-2kozsv4z.txt
summary:
  The Liver The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD) Role of diet and lifestyle changes in nonalcoholic fatty liver disease Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance The integrative biology of type 2 diabetes Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues Insulin resistance causes inflammation in adipose tissue Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling Serum adiponectin levels in different types of non alcoholic liver disease. BL, baseline; CCR2/5, C-C chemokine receptors type 2 and type 5; FXR, farnesoid X receptor; HbA 1c , glycated haemoglobin; LXR, Liver X receptor; MPC, mitochondrial pyruvate carrier; NA, data not available; NAFLD, non-alcoholic fatty liver disease; NFS, NAFLD fibrosis score; PPAR, peroxisome proliferator-activated receptor; NASH, non-alcoholic steatohepatitis; SCD, stearoyl-CoA desaturase; SGLT, sodium-glucose cotransporter; THR, thyroid hormone receptor; T2DM, type 2 diabetes.


id: cord-254404-lrsqrc2u
author: Yañez-Guerra, Luis Alfonso
title: Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling
date: 2020-06-24
extension: .txt
mime: text/plain
words: 9753
sentence: 300
flesch: 34
cache: cache/cord-254404-lrsqrc2u.txt
txt: txt/cord-254404-lrsqrc2u.txt
summary:
  Phyla in which sNPF-type peptides/precursors and sNPF-type receptors have been identified are labelled with red-filled squares. The grey square for sNPF in M. expansa, for which only transcriptome sequence data are available, indicates that sNPFtype peptides and sNPF-type receptor(s) are likely to be present in this species because sNPF-type peptides and sNPF-type receptors have been identified in another platyhelminth species, S. mediterranea, for which a genome sequence is available.


id: cord-025995-nxeg03xj
author: Gerba, Charles P.
title: Pathogen Removal from Wastewater during Groundwater Recharge
date: 2013-11-17
extension: .txt
mime: text/plain
words: 10535
sentence: 478
flesch: 51
cache: cache/cord-025995-nxeg03xj.txt
txt: txt/cord-025995-nxeg03xj.txt
summary:
  Soils differ considerably in their textural, chemical, and mineralogical prop erties and hundreds of soil types have been classified in this country Additional studies are needed on the relative re moval of bacteria and viruses by soil types.


id: cord-315094-pzixgqcy
author: Benetka, Viviane
date: 2004-03-26
extension: .txt
mime: text/plain
words: 5539
sentence: 176
flesch: 48
cache: cache/cord-315094-pzixgqcy.txt
txt: txt/cord-315094-pzixgqcy.txt
title:
  Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis

summary:
  CCV exhibits an identity to FCoV-1 KU-2 of 72%; its much closer relationship to FCoV type II than to FCoV type I can nicely be observed by the similarity of several nucleotide changes of FCoV type II and CCV. These findings demonstrate that in FIP cases FCoV type I predominates, too, nonetheless, in 14% of the cases FCoV type II was detected, suggesting its causative involvement in cases of FIP.


id: cord-329398-8o39bwv7
author: Li, Kunwei
date: 2020-03-25
extension: .txt
mime: text/plain
words: 3152
sentence: 157
flesch: 54
cache: cache/cord-329398-8o39bwv7.txt
txt: txt/cord-329398-8o39bwv7.txt
title:
  CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19)

summary:
  In a recent study done by Michael et al, they introduced a method to score the severity of inflammation on CT images based on summing up degree of acute lung inflammation lesions involvement of each lobe (including Fig. The specific situation of 5 patients in a severe-critical type which had a lower score was as follows: 3 of the 5 patients were over 70 years old; among them, 1 patient was a female smoker with diabetes, aged 80 years old, with moderate emphysema and a small amount of pleural effusion; 1 patient was a 70-year-old female, with emphysema and a small amount of pleural effusion as well; the other one was 75-year-old female with high blood pressure; the forth case was a 44-year-old male without any underlying disease; however, CT images showed only progressive lesions such as ground-glass opacification and consolidation without any fibrotic lesions (Fig. 5 ).


id: cord-316943-ef3i96bo
author: Sciberras, Justine
title: The burden of type 2 diabetes pre-and during the COVID-19 pandemic – a review
date: 2020-10-19
extension: .txt
mime: text/plain
words: 4871
sentence: 202
flesch: 41
cache: cache/cord-316943-ef3i96bo.txt
txt: txt/cord-316943-ef3i96bo.txt
summary:
  Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Spe ci a l R e p or t Renin -Angiotensin -Aldosterone System Inhibitors in Patients with Covid-19 The use of renin angiotensin system inhibitor on mortality in patients with coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome COVID-19 panic, solidarity and equity-the Malta exemplary experience Enforced inactivity in the elderly and diabetes risk: initial estimates of the burden of an unintended consequence of COVID-19 lockdown, medRxiv Clinical aspects of physical exercise for diabetes/metabolic syndrome Prevalence of obesity in Malta World Health Organization How do we identify people at high risk of type 2 diabetes and help prevent the condition from developing World Health Organization noncommunicable diseases country profiles Socioeconomic status and prevalence of type 2 diabetes in mainland China, Hong Kong and Taiwan: a systematic review Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study COVID-19 pandemic, coronaviruses, and diabetes mellitus Factors leading to high morbidity and mortality of COVID-19 in patients with type 2 diabetes Endocrine and metabolic link to coronavirus infection Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS COVID-19 and diabetes: The why, the what and the how Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensinconverting enzyme 2 COVID-19, renin-angiotensin system and endothelial dysfunction Outcomes in patients with COVID-19 infection taking ACEI/ARB Preventing a covid-19 pandemic Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?


id: cord-260793-bb4h255w
author: Brann, David H.
date: 2020-05-18
extension: .txt
mime: text/plain
words: 12011
sentence: 443
flesch: 46
cache: cache/cord-260793-bb4h255w.txt
txt: txt/cord-260793-bb4h255w.txt
title:
  Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

summary:
  medRxiv A primer on viral-associated olfactory loss in the era of COVID-19 Sudden and Complete Olfactory Loss Function as a Possible Symptom of COVID-19 European Patients with mild-to-moderate Coronavirus Disease SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells The Laboratory Mouse Comparative anatomy, physiology, and function of the upper respiratory tract Phagocytic cells in the rat olfactory epithelium after bulbectomy Supporting cells as phagocytes in the olfactory epithelium after bulbectomy Ionic conductances in sustentacular cells of the mouse olfactory epithelium Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis Olfactory epithelium: Cells, clinical disorders, and insights from an adult stem cell niche Stem and progenitor cells of the mammalian olfactory epithelium: Taking poietic license Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes A single-cell atlas of the human healthy airways A cellular census of human lungs identifies novel cell states in health and in asthma A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans Single-cell analysis of olfactory neurogenesis and differentiation in adult humans SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq Deep Sequencing of the Murine Olfactory Receptor Neuron Transcriptome Dnmt3a Regulates Global Gene Expression in Olfactory Sensory Neurons and Enables Odorant-Induced Transcription Molecular Architecture of the Mouse Nervous System Pericytes and Neurovascular Function in the Healthy and Diseased Brain Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. If humans also exhibit a similar relationship between mRNA and protein (a reasonable possibility given the precise match in olfactory cell types that express CoV-2 cell entry genes between the two species), then ACE2 protein is likely to be broadly expressed in human dorsal sustentacular cells.


id: cord-307110-eiobmxp2
author: Zhao, Shan
title: Serological Screening for Coronavirus Infections in Cats
date: 2019-08-13
extension: .txt
mime: text/plain
words: 6749
sentence: 288
flesch: 52
cache: cache/cord-307110-eiobmxp2.txt
txt: txt/cord-307110-eiobmxp2.txt
summary:
  FCoV S1 domains of both type 1 and 2, namely S1 0-CD , were expressed as murine Fc fusion proteins in HEK-293T cells as described above. S1 S1 0


id: cord-312955-gs65c3fy
author: Schreiber, Gideon
title: The Role of Type I Interferons in the Pathogenesis and Treatment of COVID-19
date: 2020-09-30
extension: .txt
mime: text/plain
words: 8440
sentence: 303
flesch: 38
cache: cache/cord-312955-gs65c3fy.txt
txt: txt/cord-312955-gs65c3fy.txt
summary:
  These data show that tight binding IFN-Is induce preferential anti-inflammatory responses, at least in this MS mouse model. Front Immunol DOI: 10.3389/fimmu.2020.595739 sha: doc_id: 312955 cord_uid: gs65c3fy Type I interferons (IFN-I) were first discovered over 60 years ago in a classical experiment by Isaacs and Lindenman, who showed that IFN-Is possess antiviral activity.


id: cord-311332-n8tvglif
author: Kostoff, Ronald N.
title: Literature-related discovery: Potential treatments and preventatives for SARS()
date: 2011-04-20
extension: .txt
mime: text/plain
words: 7199
sentence: 285
flesch: 39
cache: cache/cord-311332-n8tvglif.txt
txt: txt/cord-311332-n8tvglif.txt
summary:
  The MeSH taxonomy of Medline was used to restrict potential discoveries to selected semantic classes, and to identify potential discoveries efficiently. To enhance the volume of potential discovery, databases were used in addition to Medline.


id: cord-332186-3jy9zoz2
author: Edens, FW
title: Atypical Escherichia coli strains and their association with poult enteritis and mortality syndrome
date: 1997-07-01
extension: .txt
mime: text/plain
words: 5830
sentence: 196
flesch: 46
cache: cache/cord-332186-3jy9zoz2.txt
txt: txt/cord-332186-3jy9zoz2.txt
summary:
  During the first week after oral challenge with atypical E. coli colony Types 1 or 2, poults inoculated at 1 d had significantly reduced BW in comparison to the controls, whereas those inoculated at 6 d had BW intermediate to the controls and those inoculated at 1 d. During Week 1, poults given the CPD experienced a small but nonsignificant decrease in BW. In the groups given both CPD and one or the other of the two different atypical E. coli colony types at either 1 or 6 d, the treatment groups given atypical E. coli colony .


id: cord-347207-1u4i6qmc
author: Almomani, Huda Y.
date: 2020-07-29
extension: .txt
mime: text/plain
words: 4461
sentence: 201
flesch: 47
cache: cache/cord-347207-1u4i6qmc.txt
txt: txt/cord-347207-1u4i6qmc.txt
title:
  Randomised controlled trial of pharmacist-led patient counselling in controlling hypoglycaemic attacks in older adults with type 2 diabetes mellitus (rose-adam): A study protocol

summary:
  Several studies have established the important positive role of educational interventions on achieving glycaemic control and other clinical outcomes, however, there is still a lack in studies that evaluate the impact of such type of interventions on hypoglycaemia risk in elderly patients with type 2 diabetes. 19 56 There are several studies on the association between hypoglycaemia and patient 57 characteristics such as patients' perspectives and attitudes towards diabetes management 58 skills, self-monitoring of blood glucose, and non-adherence to anti-diabetic medications in 59 Jordanian population.


id: cord-353867-617f90wq
author: Ory, Marcia G.
date: 2020-08-30
extension: .txt
mime: text/plain
words: 6661
sentence: 240
flesch: 40
cache: cache/cord-353867-617f90wq.txt
txt: txt/cord-353867-617f90wq.txt
title:
  Implementing a Diabetes Education Program to Reduce Health Disparities in South Texas: Application of the RE-AIM Framework for Planning and Evaluation

summary:
  The majority of program participants were aged between 45 and 64 years (55.3%), female (61.6%), Hispanic (68.6%), and had high school or less education (72.2%). Table 2 shows the number and characteristics of overall program participants who attended and did not attend at each follow-up assessment.


id: cord-343982-ymaql0hx
author: Carr, M. J.
date: 2020-10-27
extension: .txt
mime: text/plain
words: 4455
sentence: 152
flesch: 46
cache: cache/cord-343982-ymaql0hx.txt
txt: txt/cord-343982-ymaql0hx.txt
title:
  Impact of COVID-19 on the diagnoses, HbA1c monitoring and mortality in people with type 2 diabetes: a UK-wide cohort study involving 13 million people in primary care

summary:
  Using primary care data from 13 million people in the UK, and 10-year historical data, we have shown that within the first 4 months of the nationwide 'lockdown' in March 2020, the indirect consequences of the COVID-19 pandemic led to: i) a 69-70% reduction in new diagnoses of type 2 diabetes, with older individuals, males, and people from deprived areas experiencing the greatest reduction in diagnosis rates; ii) a 77-84% reduction in HbA1c testing; iii) a reduction in metformin and insulin prescribing, particularly in older people with type 2 diabetes, supporting the reduced rates of diagnosis and monitoring; and iv) a short-term 110% increase in mortality rate in people with type 2 diabetes in England and a 66% increased mortality rate across the rest of the UK. A study using primary care data from Salford, UK showed 135 fewer diagnoses of type 2 diabetes than expected between March and May 2020, which amounted to a 49% reduction in activity.


id: cord-259748-x7dq1sy4
author: Wan, Dongshan
title: Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response
date: 2020-04-28
extension: .txt
mime: text/plain
words: 14188
sentence: 445
flesch: 26
cache: cache/cord-259748-x7dq1sy4.txt
txt: txt/cord-259748-x7dq1sy4.txt
summary:
  As innate immune cells, DCs have essential roles in antigen presentation, cytokine secretion, and priming the adaptive response of immune cells (176) . Subsequently, it was found that some DNA sensors can facilitate STING activation, such as interferon gamma inducible protein 16 (IFI16) (7) .


id: cord-334588-2vy4xkz6
author: Klaumann, Francini
date: 2018-12-12
extension: .txt
mime: text/plain
words: 7299
sentence: 239
flesch: 37
cache: cache/cord-334588-2vy4xkz6.txt
txt: txt/cord-334588-2vy4xkz6.txt
title:
  Current Knowledge on Porcine circovirus 3 (PCV-3): A Novel Virus With a Yet Unknown Impact on the Swine Industry

summary:
  The occurrence of porcine circovirus 3 without clinical infection signs in Shandong Province Production of a monoclonal antibody against Porcine circovirus type 3 cap protein Insights into the epidemic characteristics and evolutionary history of the novel porcine circovirus type 3 in southern China Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3 Detection and genetic characterization of Porcine circovirus type 3 in Italy Full-genome sequencing of porcine circovirus 3 field strains from Denmark, Italy and Spain demonstrates a high within-Europe genetic heterogeneity First detection of porcine circovirus type 3 on commercial pig farms in Poland Retrospective study of porcine circovirus 3 infection in China Full-Genome Sequence of Porcine Circovirus type 3 recovered from serum of sows with stillbirths in Brazil First detection and full genome sequence of porcine circovirus type 3 in Russia Retrospective detection of Porcine circovirus 3 (PCV-3) in pig serum samples from Spain Prevalence of novel porcine circovirus 3 in Korean pig populations Infection dynamics of Porcine circovirus 3 in longitudinally sampled pigs from a Spanish farm Porcine circovirus type 3 (PCV3) shedding in sow colostrum Porcine circovirus type 3 in the UK Detection and phylogenetic analysis of porcine circovirus type 3 in central China Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations Bat guano virome: predominance of dietary viruses from insects and plants plus novel mammalian viruses Virome analysis for identification of novel mammalian viruses in bat species from Chinese provinces A novel chiropteran circovirus genome recovered from a Brazilian insectivorous bat species Multiple diverse circoviruses infect farm animals and are commonly found in human and chimpanzee feces Circovirus in tissues of dogs with vasculitis and hemorrhage Novel Circovirus from Mink A very small porcine virus with circular single-stranded DNA Comparison of the Structures of Three Circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus Cloned genomic DNA of type 2 porcine circovirus is infectious when injected directly into the liver and lymph nodes of pigs: characterization of clinical disease, virus distribution, and pathologic lesions Genetic characterization of Type 2 Porcine Circovirus (PCV-2) from pigs with postweaning multisystemic wasting syndrome in different geographic regions of north America and development of a differential PCR-restriction fragment length polymorphism assay Sequence of porcine circovirus DNA: affinities with plant circoviruses Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains Genetic and phylogenetic analysis of a new porcine circovirus type 2 (PCV2) strain in China Porcine circovirus type 2 (PCV2): genetic variation and newly emerging genotypes in China Occurrence and role of an early antigen and evidence for transforming ability of porcine circovirus Mapping and characterization of the origin of DNA replication of porcine circovirus Identification and functional analysis of the novel ORF4 protein encoded by porcine circovirus Type 2 ORF4-protein deficient PCV2 mutants enhance virus-induced apoptosis and show differential expression of mRNAs in vitro Caspase-dependent apoptosis induction via viral protein ORF4 of porcine circovirus 2 binding to mitochondrial adenine nucleotide translocase 3 Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs Molecular biology of Porcine circovirus: analyses of gene expression and viral replication A field guide to eukaryotic circular singlestranded DNA viruses:


id: cord-355239-fc52dn3v
author: Kato, Kentaro
title: The Role of Carbohydrates in Infection Strategies of Enteric Pathogens
date: 2014-11-15
extension: .txt
mime: text/plain
words: 6801
sentence: 303
flesch: 39
cache: cache/cord-355239-fc52dn3v.txt
txt: txt/cord-355239-fc52dn3v.txt
summary:
  The surface of Toxoplasma: more and less Targeted disruption of the glycosylphosphatidylinositolanchored surface antigen SAG3 gene in Toxoplasma gondii decreases host cell adhesion and drastically reduces virulence in mice Toxoplasma gondii: the role of parasite surface and secreted proteins in host cell invasion Recently, the surface proteins of apicomplexan parasites have also been reported to bind to carbohydrates on host cells [3] .


id: cord-265005-e6rpryrh
author: Tomasello, Elena
date: 2014-10-30
extension: .txt
mime: text/plain
words: 18121
sentence: 594
flesch: 29
cache: cache/cord-265005-e6rpryrh.txt
txt: txt/cord-265005-e6rpryrh.txt
title:
  Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types

summary:
  Further knowledge on the functions and the dynamic regulation of ISGs is essential to develop novel therapeutic strategies against viral infections aiming at modulating IFN responses to promote their protective anti-viral cell-intrinsic functions over their deleterious toxic effects. This inhibition is relieved upon cell infection through negative regulation of the function of the RNA-induced silencing complex.


id: cord-018595-x3tleomb
author: Dodiuk-Gad, Roni P.
title: Adverse Medication Reactions
date: 2017-04-25
extension: .txt
mime: text/plain
words: 16329
sentence: 800
flesch: 37
cache: cache/cord-018595-x3tleomb.txt
txt: txt/cord-018595-x3tleomb.txt
summary:
  In view of the large diversity of cutaneous drug reactions, it is helpful to approach them as clinicopathologic entities and to base the diagnosis on a combination of clinical, histo- logical and disease course data [89] . Heightened awareness of the possible mimicry of other skin diseases and of the suspicious histopathological clues pointing to drug etiology are key elements to the appropriate histological diagnosis of drug reactions in the skin [85, 88, 89] .


id: cord-343409-oao75pzy
author: Hayward, Joshua A
title: Identification of diverse full-length endogenous betaretroviruses in megabats and microbats
date: 2013-03-27
extension: .txt
mime: text/plain
words: 11607
sentence: 445
flesch: 45
cache: cache/cord-343409-oao75pzy.txt
txt: txt/cord-343409-oao75pzy.txt
summary:
  All of the reference sequences were downloaded from NCBI (Additional file 2: Table S5 ) and aligned with bat sequences using MUSCLE [68] . The gag, pol, and env genes of each genome sequence were translated into protein sequences using the CLC Main Workbench 6.6 (CLC Bio).


id: cord-344093-3bniy5b5
author: Peteranderl, Christin
date: 2017-03-22
extension: .txt
mime: text/plain
words: 12579
sentence: 335
flesch: 18
cache: cache/cord-344093-3bniy5b5.txt
txt: txt/cord-344093-3bniy5b5.txt
title:
  The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond

summary:
  In addition, Davidson et al. (74) demonstrated that type I IFN application to IAVinfected mice increased morbidity and lung injury, which could be attributed to both DR5 and TRAIL upregulation inducing epithelial cell apoptosis. In line, Pinto et al. (92) reported an impairment of T cell responses upon type IFN induction in West Nile virus infection.


id: cord-336201-fl606l3b
author: Daryabor, Gholamreza
title: The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System
date: 2020-07-22
extension: .txt
mime: text/plain
words: 13880
sentence: 438
flesch: 25
cache: cache/cord-336201-fl606l3b.txt
txt: txt/cord-336201-fl606l3b.txt
summary:
  The endocrine part is made of different cell types, including α, β, δ, and ε cells that secrete glucagon, insulin, somatostatin, and ghrelin hormones, respectively. A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2 Novel clearance mechanisms of platelets Flow cytometric analysis of platelets type 2 diabetes mellitus reveals 'angry' platelets Platelet activity and hypercoagulation in type 2 diabetes Increased circulating resistin is associated with insulin resistance, oxidative stress and platelet activation in type 2 diabetes mellitus Increased levels of soluble adhesion molecules in type 2 (non-insulin dependent) diabetes mellitus are independent of glycaemic control Molecular mechanisms underpinning microparticle-mediated cellular injury in cardiovascular complications associated with diabetes Association between mean platelet volume in the pathogenesis of type 2 diabetes mellitus and diabetic macrovascular complications in Japanese patients Increased erythrocyte-and platelet-derived microvesicles in newly diagnosed type 2 diabetes mellitus Type 2 diabetes and cardiovascular disease: have all risk factors the same strength? Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36 Central role of the P2Y12 receptor in platelet activation Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model Introduction to the human gut microbiota Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection Faecalibacterium prausnitzii-derived microbial anti-inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression Considering gut microbiota in treatment of type 2 diabetes mellitus Metformin effect on gut microbiota: insights for HIV-related inflammation The bacterium Akkermansia muciniphila: a sentinel for gut permeability and its relevance to HIV-related inflammation High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells The role of iron in diabetes and its complications Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCalpha-dependent manner Betacell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Fatty acid-induced lipotoxicity in pancreatic beta-cells during development of type 2 diabetes Mesenchymal stem cell therapy in type 2 diabetes mellitus Establishment of insulin-producing cells from human embryonic stem cells underhypoxic condition for cell based therapy Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction A simple method for the generation of insulin producing cells from bone marrow mesenchymal stem cells Secretagogin affects insulin secretion in pancreatic beta-cells by regulating actin dynamics and focal adhesion Secretagogin regulates insulin signaling by direct insulin binding.


id: cord-326785-le2t1l8g
title: Pathological Society of Great Britain and Ireland. 163rd meeting, 3–5 July 1991
date: 2005-06-15
extension: .txt
mime: text/plain
words: 22778
sentence: 1352
flesch: 36
cache: cache/cord-326785-le2t1l8g.txt
txt: txt/cord-326785-le2t1l8g.txt
summary:
  SSCs in the Connective tissue were Melled with the antibody along With a number of other cells (lymphocytes) within the germinal centres. These results show that sadium iodoacetate reduces cell number and interferes wqth the manufacture of matrix components.


id: cord-335382-fk4um9nw
author: Farver, Carol F.
title: Molecular Basis of Pulmonary Disease
date: 2012-08-10
extension: .txt
mime: text/plain
words: 32359
sentence: 1449
flesch: 38
cache: cache/cord-335382-fk4um9nw.txt
txt: txt/cord-335382-fk4um9nw.txt
summary:
  In hyperoxia-induced cell death, hyperoxia may induce the expression of angiopoietin 2 (Ang2) in lung epithelial cells. Annual report to the nation on the status of cancer Pathology and Genetics of Tumours of the Lung, Pleura AJCC Cancer Staging Manual varying), National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released Diagnosis and management of lung cancer executive summary: ACCP evidence-based clinical practice guidelines Genetics of preneoplasia: Lessons from lung cancer Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH Lung cancer preneoplasia Characterizing the cancer genome in lung adenocarcinoma Focus on lung cancer New molecularly targeted therapies for lung cancer High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints Genetic and molecular alterations Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma Hereditary cancers disclose a class of cancer genes Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers Molecular oncogenesis of lung cancer Molecular genetics of lung cancer The P16/cyclin D1/


id: cord-017248-a37t31u1
title: Alphabetic Listing of Diseases and Conditions
date: 2010-05-17
extension: .txt
mime: text/plain
words: 48773
sentence: 3342
flesch: 37
cache: cache/cord-017248-a37t31u1.txt
txt: txt/cord-017248-a37t31u1.txt
summary:
  Peptic ulcers may be associated with emphysema,* tuberculosis,* and other chronic pulmonary diseases. Procedures See under Alcoholism and alcohol intoxication.


id: cord-026005-f2khcjdy
author: López, Alfonso
title: Respiratory System, Mediastinum, and Pleurae
date: 2017-02-17
extension: .txt
mime: text/plain
words: 57351
sentence: 2547
flesch: 32
cache: cache/cord-026005-f2khcjdy.txt
txt: txt/cord-026005-f2khcjdy.txt
summary:
  Lung disease can have profound systemic effects when cytokines, produced locally during necrosis or inflammation, are released into circulation. Alveolar filling disorders are a heterogeneous group of lung diseases characterized by accumulation of various chemical compounds in the alveolar lumens.


id: cord-004879-pgyzluwp
title: Programmed cell death
date: 1994
extension: .txt
mime: text/plain
words: 81833
sentence: 3672
flesch: 47
cache: cache/cord-004879-pgyzluwp.txt
txt: txt/cord-004879-pgyzluwp.txt
summary:
  8cl-2(z is a mitochondrial or perinuclear-associated oncoprotein that prolongs the life span of a variety of cell types by interfering with programmed cell death. Single and repetitive uptake and release of CPZ were measured in each cell type after individual exposure or exposure in any combination of cell types: In 2 hour competitive uptake studies fibreblasts reached 1.7 and 2.6 times the concentrations of C6-and ROC-cells, :respectively.


id: cord-350571-6tapkjb6
date: 2017-01-10
extension: .txt
mime: text/plain
words: 106086
sentence: 5201
flesch: 45
cache: cache/cord-350571-6tapkjb6.txt
txt: txt/cord-350571-6tapkjb6.txt
title:
  45th ESCP-NSF international symposium on clinical pharmacy: clinical pharmacy tackling inequalities and access to health care. Oslo, Norway, 5–7 October 2016

summary:
  Clinical pharmacists have a role to evaluate and optimize the appropriateness and effectiveness of patient's medications. DTSIs interventions (treatment group) consist in: motivational interview, sharing and delivery of printed, explanatory material in the patient's native language, reconciliation of patients medications at hospital admission and at discharge; identification of potential risks due to drug-drug interactions; monitoring of compliance to drug therapy, and finally detection of adverse drug reactions (ADRs) occurring in the course of care.


id: cord-010119-t1x9gknd
title: Abstract Presentations from the AABB Annual Meeting San Diego, CA ctober 7‐10, 2017
date: 2017-09-04
extension: .txt
mime: text/plain
words: 230433
sentence: 10311
flesch: 50
cache: cache/cord-010119-t1x9gknd.txt
txt: txt/cord-010119-t1x9gknd.txt
summary:
  Probability of occurrence of cannabis metabolites in blood donor samples is likely to be highly variable across donor centers and is largely dependent on blood donor demographics. OBRR, CBER, FDA Background/Case Studies: Extended molecular typing of a large number of blood donors can increase the likelihood of identifying donor red blood cells (RBCs) that match those of the recipient.


# ent

id: cord-314328-gft6phd6
sid: 80
eid: 1
type: PERSON
entity:
  c. lawrence https://orcid.org/0000-0002-0995-5714 c. smart https://orcid.org/0000-0003-3104-8800 b. r. king


id: cord-326785-le2t1l8g
sid: 628
eid: 1
type: PERSON
entity:
  radialiond~dnotaffecttheprevalenceofthethreepnenotypesbutincreasedthefrequencyofmpasposltlvecryptsinanegativebackground(t6


id: cord-326785-le2t1l8g
sid: 1229
eid: 1
type: PERSON
entity:
  myxold androundcell lipsarcomarepresentthemost commanfarmofsarcomaaccuningmearlytamidadunlifeandare commoniy


# pos

id: cord-326785-le2t1l8g
sid: 628
tid: 3
pos: PROPN
token:
  dnotaffecttheprevalenceofthethreepnenotypesbutincreasedthefrequencyofmpasposltlvecryptsinanegativebackground(t6

lemma:
  dnotaffecttheprevalenceofthethreepnenotypesbutincreasedthefrequencyofmpasposltlvecryptsinanegativebackground(t6


