id	sid	tid	token	lemma	pos
cord-000079-533xlisc	1	1	key	key	ADJ
cord-000079-533xlisc	1	2	:	:	PUNCT
cord-000079-533xlisc	1	3	cord-000079	cord-000079	NOUN
cord-000079-533xlisc	1	4	-	-	PUNCT
cord-000079-533xlisc	1	5	533xlisc	533xlisc	PROPN
cord-000079-533xlisc	1	6	authors	author	NOUN
cord-000079-533xlisc	1	7	:	:	PUNCT
cord-000079-533xlisc	1	8	huszthy	huszthy	PROPN
cord-000079-533xlisc	1	9	,	,	PUNCT
cord-000079-533xlisc	1	10	peter	peter	PROPN
cord-000079-533xlisc	1	11	c.	c.	PROPN
cord-000079-533xlisc	1	12	;	;	PUNCT
cord-000079-533xlisc	1	13	giroglou	giroglou	PROPN
cord-000079-533xlisc	1	14	,	,	PUNCT
cord-000079-533xlisc	1	15	tsanan	tsanan	PROPN
cord-000079-533xlisc	1	16	;	;	PUNCT
cord-000079-533xlisc	1	17	tsinkalovsky	tsinkalovsky	NOUN
cord-000079-533xlisc	1	18	,	,	PUNCT
cord-000079-533xlisc	1	19	oleg	oleg	PROPN
cord-000079-533xlisc	1	20	;	;	PUNCT
cord-000079-533xlisc	1	21	euskirchen	euskirchen	PROPN
cord-000079-533xlisc	1	22	,	,	PUNCT
cord-000079-533xlisc	1	23	philipp	philipp	NOUN
cord-000079-533xlisc	1	24	;	;	PUNCT
cord-000079-533xlisc	1	25	skaftnesmo	skaftnesmo	PROPN
cord-000079-533xlisc	1	26	,	,	PUNCT
cord-000079-533xlisc	1	27	kai	kai	PROPN
cord-000079-533xlisc	1	28	ove	ove	PROPN
cord-000079-533xlisc	1	29	;	;	PUNCT
cord-000079-533xlisc	1	30	bjerkvig	bjerkvig	PROPN
cord-000079-533xlisc	1	31	,	,	PUNCT
cord-000079-533xlisc	1	32	rolf	rolf	PROPN
cord-000079-533xlisc	1	33	;	;	PUNCT
cord-000079-533xlisc	1	34	von	von	PROPN
cord-000079-533xlisc	1	35	laer	laer	PROPN
cord-000079-533xlisc	1	36	,	,	PUNCT
cord-000079-533xlisc	1	37	dorothee	dorothee	NOUN
cord-000079-533xlisc	1	38	;	;	PUNCT
cord-000079-533xlisc	1	39	miletic	miletic	ADJ
cord-000079-533xlisc	1	40	,	,	PUNCT
cord-000079-533xlisc	1	41	hrvoje	hrvoje	PROPN
cord-000079-533xlisc	1	42	title	title	NOUN
cord-000079-533xlisc	1	43	:	:	PUNCT
cord-000079-533xlisc	1	44	remission	remission	NOUN
cord-000079-533xlisc	1	45	of	of	ADP
cord-000079-533xlisc	1	46	invasive	invasive	ADJ
cord-000079-533xlisc	1	47	,	,	PUNCT
cord-000079-533xlisc	1	48	cancer	cancer	NOUN
cord-000079-533xlisc	1	49	stem	stem	NOUN
cord-000079-533xlisc	1	50	-	-	PUNCT
cord-000079-533xlisc	1	51	like	like	ADJ
cord-000079-533xlisc	1	52	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	1	53	xenografts	xenograft	NOUN
cord-000079-533xlisc	1	54	using	use	VERB
cord-000079-533xlisc	1	55	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	1	56	vector	vector	NOUN
cord-000079-533xlisc	1	57	-	-	PUNCT
cord-000079-533xlisc	1	58	mediated	mediate	VERB
cord-000079-533xlisc	1	59	suicide	suicide	NOUN
cord-000079-533xlisc	1	60	gene	gene	NOUN
cord-000079-533xlisc	1	61	therapy	therapy	NOUN
cord-000079-533xlisc	1	62	date	date	NOUN
cord-000079-533xlisc	1	63	:	:	PUNCT
cord-000079-533xlisc	1	64	2009	2009	NUM
cord-000079-533xlisc	1	65	-	-	SYM
cord-000079-533xlisc	1	66	07	07	NUM
cord-000079-533xlisc	1	67	-	-	SYM
cord-000079-533xlisc	1	68	20	20	NUM
cord-000079-533xlisc	1	69	journal	journal	NOUN
cord-000079-533xlisc	1	70	:	:	PUNCT
cord-000079-533xlisc	1	71	plos	plo	VERB
cord-000079-533xlisc	1	72	one	one	NUM
cord-000079-533xlisc	1	73	doi	doi	PROPN
cord-000079-533xlisc	1	74	:	:	PUNCT
cord-000079-533xlisc	1	75	10.1371	10.1371	NUM
cord-000079-533xlisc	1	76	/	/	SYM
cord-000079-533xlisc	1	77	journal.pone.0006314	journal.pone.0006314	PROPN
cord-000079-533xlisc	1	78	sha	shall	AUX
cord-000079-533xlisc	1	79	:	:	PUNCT
cord-000079-533xlisc	1	80	doc_id	doc_id	X
cord-000079-533xlisc	1	81	:	:	PUNCT
cord-000079-533xlisc	1	82	79	79	NUM
cord-000079-533xlisc	1	83	cord_uid	cord_uid	PROPN
cord-000079-533xlisc	1	84	:	:	PUNCT
cord-000079-533xlisc	1	85	533xlisc	533xlisc	PROPN
cord-000079-533xlisc	1	86	background	background	NOUN
cord-000079-533xlisc	1	87	:	:	PUNCT
cord-000079-533xlisc	1	88	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	1	89	is	be	AUX
cord-000079-533xlisc	1	90	the	the	DET
cord-000079-533xlisc	1	91	most	most	ADV
cord-000079-533xlisc	1	92	frequent	frequent	ADJ
cord-000079-533xlisc	1	93	and	and	CCONJ
cord-000079-533xlisc	1	94	most	most	ADV
cord-000079-533xlisc	1	95	malignant	malignant	ADJ
cord-000079-533xlisc	1	96	primary	primary	ADJ
cord-000079-533xlisc	1	97	brain	brain	NOUN
cord-000079-533xlisc	1	98	tumor	tumor	NOUN
cord-000079-533xlisc	1	99	with	with	ADP
cord-000079-533xlisc	1	100	a	a	DET
cord-000079-533xlisc	1	101	poor	poor	ADJ
cord-000079-533xlisc	1	102	prognosis	prognosis	NOUN
cord-000079-533xlisc	1	103	.	.	PUNCT
cord-000079-533xlisc	2	1	the	the	DET
cord-000079-533xlisc	2	2	translation	translation	NOUN
cord-000079-533xlisc	2	3	of	of	ADP
cord-000079-533xlisc	2	4	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	2	5	strategies	strategy	NOUN
cord-000079-533xlisc	2	6	for	for	ADP
cord-000079-533xlisc	2	7	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	2	8	from	from	ADP
cord-000079-533xlisc	2	9	the	the	DET
cord-000079-533xlisc	2	10	experimental	experimental	ADJ
cord-000079-533xlisc	2	11	phase	phase	NOUN
cord-000079-533xlisc	2	12	into	into	ADP
cord-000079-533xlisc	2	13	the	the	DET
cord-000079-533xlisc	2	14	clinic	clinic	NOUN
cord-000079-533xlisc	2	15	has	have	AUX
cord-000079-533xlisc	2	16	been	be	AUX
cord-000079-533xlisc	2	17	limited	limit	VERB
cord-000079-533xlisc	2	18	by	by	ADP
cord-000079-533xlisc	2	19	insufficient	insufficient	ADJ
cord-000079-533xlisc	2	20	animal	animal	NOUN
cord-000079-533xlisc	2	21	models	model	NOUN
cord-000079-533xlisc	2	22	,	,	PUNCT
cord-000079-533xlisc	2	23	which	which	PRON
cord-000079-533xlisc	2	24	lack	lack	VERB
cord-000079-533xlisc	2	25	important	important	ADJ
cord-000079-533xlisc	2	26	features	feature	NOUN
cord-000079-533xlisc	2	27	of	of	ADP
cord-000079-533xlisc	2	28	human	human	ADJ
cord-000079-533xlisc	2	29	tumors	tumor	NOUN
cord-000079-533xlisc	2	30	.	.	PUNCT
cord-000079-533xlisc	3	1	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	3	2	gene	gene	NOUN
cord-000079-533xlisc	3	3	therapy	therapy	NOUN
cord-000079-533xlisc	3	4	is	be	AUX
cord-000079-533xlisc	3	5	an	an	DET
cord-000079-533xlisc	3	6	attractive	attractive	ADJ
cord-000079-533xlisc	3	7	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	3	8	option	option	NOUN
cord-000079-533xlisc	3	9	for	for	ADP
cord-000079-533xlisc	3	10	human	human	ADJ
cord-000079-533xlisc	3	11	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	3	12	,	,	PUNCT
cord-000079-533xlisc	3	13	which	which	PRON
cord-000079-533xlisc	3	14	we	we	PRON
cord-000079-533xlisc	3	15	validated	validate	VERB
cord-000079-533xlisc	3	16	in	in	ADP
cord-000079-533xlisc	3	17	a	a	DET
cord-000079-533xlisc	3	18	clinically	clinically	ADV
cord-000079-533xlisc	3	19	relevant	relevant	ADJ
cord-000079-533xlisc	3	20	animal	animal	NOUN
cord-000079-533xlisc	3	21	model	model	NOUN
cord-000079-533xlisc	3	22	.	.	PUNCT
cord-000079-533xlisc	4	1	methodology	methodology	NOUN
cord-000079-533xlisc	4	2	/	/	SYM
cord-000079-533xlisc	4	3	principal	principal	ADJ
cord-000079-533xlisc	4	4	findings	finding	NOUN
cord-000079-533xlisc	4	5	:	:	PUNCT
cord-000079-533xlisc	4	6	we	we	PRON
cord-000079-533xlisc	4	7	used	use	VERB
cord-000079-533xlisc	4	8	a	a	DET
cord-000079-533xlisc	4	9	rodent	rodent	ADJ
cord-000079-533xlisc	4	10	xenograft	xenograft	PROPN
cord-000079-533xlisc	4	11	model	model	NOUN
cord-000079-533xlisc	4	12	that	that	PRON
cord-000079-533xlisc	4	13	recapitulates	recapitulate	VERB
cord-000079-533xlisc	4	14	the	the	DET
cord-000079-533xlisc	4	15	invasive	invasive	ADJ
cord-000079-533xlisc	4	16	and	and	CCONJ
cord-000079-533xlisc	4	17	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	4	18	features	feature	NOUN
cord-000079-533xlisc	4	19	of	of	ADP
cord-000079-533xlisc	4	20	human	human	ADJ
cord-000079-533xlisc	4	21	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	4	22	to	to	PART
cord-000079-533xlisc	4	23	analyze	analyze	VERB
cord-000079-533xlisc	4	24	the	the	DET
cord-000079-533xlisc	4	25	transduction	transduction	NOUN
cord-000079-533xlisc	4	26	pattern	pattern	NOUN
cord-000079-533xlisc	4	27	and	and	CCONJ
cord-000079-533xlisc	4	28	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	4	29	efficacy	efficacy	NOUN
cord-000079-533xlisc	4	30	of	of	ADP
cord-000079-533xlisc	4	31	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	4	32	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	4	33	vectors	vector	NOUN
cord-000079-533xlisc	4	34	.	.	PUNCT
cord-000079-533xlisc	5	1	both	both	DET
cord-000079-533xlisc	5	2	,	,	PUNCT
cord-000079-533xlisc	5	3	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	5	4	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	5	5	virus	virus	NOUN
cord-000079-533xlisc	5	6	glycoprotein	glycoprotein	NOUN
cord-000079-533xlisc	5	7	(	(	PUNCT
cord-000079-533xlisc	5	8	lcmv	lcmv	PROPN
cord-000079-533xlisc	5	9	-	-	PUNCT
cord-000079-533xlisc	5	10	gp	gp	PROPN
cord-000079-533xlisc	5	11	)	)	PUNCT
cord-000079-533xlisc	5	12	and	and	CCONJ
cord-000079-533xlisc	5	13	vesicular	vesicular	ADJ
cord-000079-533xlisc	5	14	stomatitis	stomatitis	NOUN
cord-000079-533xlisc	5	15	virus	virus	NOUN
cord-000079-533xlisc	5	16	glycoprotein	glycoprotein	NOUN
cord-000079-533xlisc	5	17	(	(	PUNCT
cord-000079-533xlisc	5	18	vsv	vsv	PROPN
cord-000079-533xlisc	5	19	-	-	PROPN
cord-000079-533xlisc	5	20	g	g	PROPN
cord-000079-533xlisc	5	21	)	)	PUNCT
cord-000079-533xlisc	5	22	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	5	23	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	5	24	vectors	vector	NOUN
cord-000079-533xlisc	5	25	very	very	ADV
cord-000079-533xlisc	5	26	efficiently	efficiently	ADV
cord-000079-533xlisc	5	27	transduced	transduce	VERB
cord-000079-533xlisc	5	28	human	human	ADJ
cord-000079-533xlisc	5	29	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	5	30	cells	cell	NOUN
cord-000079-533xlisc	5	31	in	in	ADP
cord-000079-533xlisc	5	32	vitro	vitro	X
cord-000079-533xlisc	5	33	and	and	CCONJ
cord-000079-533xlisc	5	34	in	in	ADP
cord-000079-533xlisc	5	35	vivo	vivo	NOUN
cord-000079-533xlisc	5	36	.	.	PUNCT
cord-000079-533xlisc	6	1	in	in	ADP
cord-000079-533xlisc	6	2	contrast	contrast	NOUN
cord-000079-533xlisc	6	3	,	,	PUNCT
cord-000079-533xlisc	6	4	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	6	5	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	6	6	vectors	vector	NOUN
cord-000079-533xlisc	6	7	,	,	PUNCT
cord-000079-533xlisc	6	8	similar	similar	ADJ
cord-000079-533xlisc	6	9	to	to	ADP
cord-000079-533xlisc	6	10	those	those	PRON
cord-000079-533xlisc	6	11	evaluated	evaluate	VERB
cord-000079-533xlisc	6	12	for	for	ADP
cord-000079-533xlisc	6	13	clinical	clinical	ADJ
cord-000079-533xlisc	6	14	therapy	therapy	NOUN
cord-000079-533xlisc	6	15	of	of	ADP
cord-000079-533xlisc	6	16	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	6	17	,	,	PUNCT
cord-000079-533xlisc	6	18	showed	show	VERB
cord-000079-533xlisc	6	19	inefficient	inefficient	ADJ
cord-000079-533xlisc	6	20	gene	gene	NOUN
cord-000079-533xlisc	6	21	transfer	transfer	NOUN
cord-000079-533xlisc	6	22	in	in	ADP
cord-000079-533xlisc	6	23	vitro	vitro	X
cord-000079-533xlisc	6	24	and	and	CCONJ
cord-000079-533xlisc	6	25	in	in	ADP
cord-000079-533xlisc	6	26	vivo	vivo	NOUN
cord-000079-533xlisc	6	27	.	.	PUNCT
cord-000079-533xlisc	7	1	both	both	DET
cord-000079-533xlisc	7	2	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	7	3	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	7	4	vectors	vector	NOUN
cord-000079-533xlisc	7	5	transduced	transduce	VERB
cord-000079-533xlisc	7	6	cancer	cancer	NOUN
cord-000079-533xlisc	7	7	stem	stem	NOUN
cord-000079-533xlisc	7	8	-	-	PUNCT
cord-000079-533xlisc	7	9	like	like	ADJ
cord-000079-533xlisc	7	10	cells	cell	NOUN
cord-000079-533xlisc	7	11	characterized	characterize	VERB
cord-000079-533xlisc	7	12	by	by	ADP
cord-000079-533xlisc	7	13	their	their	PRON
cord-000079-533xlisc	7	14	cd133-	cd133-	NOUN
cord-000079-533xlisc	7	15	,	,	PUNCT
cord-000079-533xlisc	7	16	nestinand	nestinand	PROPN
cord-000079-533xlisc	7	17	sox2	sox2	PROPN
cord-000079-533xlisc	7	18	-	-	PUNCT
cord-000079-533xlisc	7	19	expression	expression	NOUN
cord-000079-533xlisc	7	20	,	,	PUNCT
cord-000079-533xlisc	7	21	the	the	DET
cord-000079-533xlisc	7	22	ability	ability	NOUN
cord-000079-533xlisc	7	23	to	to	PART
cord-000079-533xlisc	7	24	form	form	VERB
cord-000079-533xlisc	7	25	spheroids	spheroid	NOUN
cord-000079-533xlisc	7	26	in	in	ADP
cord-000079-533xlisc	7	27	neural	neural	ADJ
cord-000079-533xlisc	7	28	stem	stem	NOUN
cord-000079-533xlisc	7	29	cell	cell	NOUN
cord-000079-533xlisc	7	30	medium	medium	NOUN
cord-000079-533xlisc	7	31	and	and	CCONJ
cord-000079-533xlisc	7	32	to	to	PART
cord-000079-533xlisc	7	33	express	express	VERB
cord-000079-533xlisc	7	34	astrocytic	astrocytic	ADJ
cord-000079-533xlisc	7	35	and	and	CCONJ
cord-000079-533xlisc	7	36	neuronal	neuronal	ADJ
cord-000079-533xlisc	7	37	differentiation	differentiation	NOUN
cord-000079-533xlisc	7	38	markers	marker	NOUN
cord-000079-533xlisc	7	39	under	under	ADP
cord-000079-533xlisc	7	40	serum	serum	NOUN
cord-000079-533xlisc	7	41	conditions	condition	NOUN
cord-000079-533xlisc	7	42	.	.	PUNCT
cord-000079-533xlisc	8	1	in	in	ADP
cord-000079-533xlisc	8	2	a	a	DET
cord-000079-533xlisc	8	3	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	8	4	approach	approach	NOUN
cord-000079-533xlisc	8	5	using	use	VERB
cord-000079-533xlisc	8	6	the	the	DET
cord-000079-533xlisc	8	7	suicide	suicide	NOUN
cord-000079-533xlisc	8	8	gene	gene	NOUN
cord-000079-533xlisc	8	9	herpes	herpe	NOUN
cord-000079-533xlisc	8	10	simplex	simplex	ADJ
cord-000079-533xlisc	8	11	virus	virus	NOUN
cord-000079-533xlisc	8	12	thymidine	thymidine	NOUN
cord-000079-533xlisc	8	13	kinase	kinase	NOUN
cord-000079-533xlisc	8	14	(	(	PUNCT
cord-000079-533xlisc	8	15	hsv-1	hsv-1	NOUN
cord-000079-533xlisc	8	16	-	-	PUNCT
cord-000079-533xlisc	8	17	tk	tk	PROPN
cord-000079-533xlisc	8	18	)	)	PUNCT
cord-000079-533xlisc	8	19	fused	fuse	VERB
cord-000079-533xlisc	8	20	to	to	ADP
cord-000079-533xlisc	8	21	egfp	egfp	NOUN
cord-000079-533xlisc	8	22	,	,	PUNCT
cord-000079-533xlisc	8	23	both	both	DET
cord-000079-533xlisc	8	24	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	8	25	vectors	vector	NOUN
cord-000079-533xlisc	8	26	mediated	mediate	VERB
cord-000079-533xlisc	8	27	a	a	DET
cord-000079-533xlisc	8	28	complete	complete	ADJ
cord-000079-533xlisc	8	29	remission	remission	NOUN
cord-000079-533xlisc	8	30	of	of	ADP
cord-000079-533xlisc	8	31	solid	solid	ADJ
cord-000079-533xlisc	8	32	tumors	tumor	NOUN
cord-000079-533xlisc	8	33	as	as	SCONJ
cord-000079-533xlisc	8	34	seen	see	VERB
cord-000079-533xlisc	8	35	on	on	ADP
cord-000079-533xlisc	8	36	mri	mri	NOUN
cord-000079-533xlisc	8	37	resulting	result	VERB
cord-000079-533xlisc	8	38	in	in	ADP
cord-000079-533xlisc	8	39	a	a	DET
cord-000079-533xlisc	8	40	highly	highly	ADV
cord-000079-533xlisc	8	41	significant	significant	ADJ
cord-000079-533xlisc	8	42	survival	survival	NOUN
cord-000079-533xlisc	8	43	benefit	benefit	NOUN
cord-000079-533xlisc	8	44	(	(	PUNCT
cord-000079-533xlisc	8	45	p<0.001	p<0.001	NUM
cord-000079-533xlisc	8	46	)	)	PUNCT
cord-000079-533xlisc	8	47	compared	compare	VERB
cord-000079-533xlisc	8	48	to	to	ADP
cord-000079-533xlisc	8	49	control	control	NOUN
cord-000079-533xlisc	8	50	groups	group	NOUN
cord-000079-533xlisc	8	51	.	.	PUNCT
cord-000079-533xlisc	9	1	in	in	ADP
cord-000079-533xlisc	9	2	all	all	DET
cord-000079-533xlisc	9	3	recurrent	recurrent	ADJ
cord-000079-533xlisc	9	4	tumors	tumor	NOUN
cord-000079-533xlisc	9	5	,	,	PUNCT
cord-000079-533xlisc	9	6	surviving	survive	VERB
cord-000079-533xlisc	9	7	egfp	egfp	NOUN
cord-000079-533xlisc	9	8	-	-	PUNCT
cord-000079-533xlisc	9	9	positive	positive	ADJ
cord-000079-533xlisc	9	10	tumor	tumor	NOUN
cord-000079-533xlisc	9	11	cells	cell	NOUN
cord-000079-533xlisc	9	12	were	be	AUX
cord-000079-533xlisc	9	13	found	find	VERB
cord-000079-533xlisc	9	14	,	,	PUNCT
cord-000079-533xlisc	9	15	advocating	advocate	VERB
cord-000079-533xlisc	9	16	prodrug	prodrug	NOUN
cord-000079-533xlisc	9	17	application	application	NOUN
cord-000079-533xlisc	9	18	for	for	ADP
cord-000079-533xlisc	9	19	several	several	ADJ
cord-000079-533xlisc	9	20	cycles	cycle	NOUN
cord-000079-533xlisc	9	21	to	to	PART
cord-000079-533xlisc	9	22	even	even	ADV
cord-000079-533xlisc	9	23	enhance	enhance	VERB
cord-000079-533xlisc	9	24	and	and	CCONJ
cord-000079-533xlisc	9	25	prolong	prolong	VERB
cord-000079-533xlisc	9	26	the	the	DET
cord-000079-533xlisc	9	27	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	9	28	effect	effect	NOUN
cord-000079-533xlisc	9	29	.	.	PUNCT
cord-000079-533xlisc	10	1	conclusions	conclusion	NOUN
cord-000079-533xlisc	10	2	/	/	SYM
cord-000079-533xlisc	10	3	significance	significance	NOUN
cord-000079-533xlisc	10	4	:	:	PUNCT
cord-000079-533xlisc	10	5	in	in	ADP
cord-000079-533xlisc	10	6	conclusion	conclusion	NOUN
cord-000079-533xlisc	10	7	,	,	PUNCT
cord-000079-533xlisc	10	8	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	10	9	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	10	10	vectors	vector	NOUN
cord-000079-533xlisc	10	11	are	be	AUX
cord-000079-533xlisc	10	12	promising	promise	VERB
cord-000079-533xlisc	10	13	candidates	candidate	NOUN
cord-000079-533xlisc	10	14	for	for	ADP
cord-000079-533xlisc	10	15	gene	gene	NOUN
cord-000079-533xlisc	10	16	therapy	therapy	NOUN
cord-000079-533xlisc	10	17	of	of	ADP
cord-000079-533xlisc	10	18	glioma	glioma	NOUN
cord-000079-533xlisc	10	19	in	in	ADP
cord-000079-533xlisc	10	20	patients	patient	NOUN
cord-000079-533xlisc	10	21	.	.	PUNCT
cord-000079-533xlisc	11	1	the	the	DET
cord-000079-533xlisc	11	2	inefficient	inefficient	ADJ
cord-000079-533xlisc	11	3	gene	gene	NOUN
cord-000079-533xlisc	11	4	delivery	delivery	NOUN
cord-000079-533xlisc	11	5	by	by	ADP
cord-000079-533xlisc	11	6	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	11	7	vectors	vector	NOUN
cord-000079-533xlisc	11	8	is	be	AUX
cord-000079-533xlisc	11	9	in	in	ADP
cord-000079-533xlisc	11	10	line	line	NOUN
cord-000079-533xlisc	11	11	with	with	ADP
cord-000079-533xlisc	11	12	the	the	DET
cord-000079-533xlisc	11	13	results	result	NOUN
cord-000079-533xlisc	11	14	obtained	obtain	VERB
cord-000079-533xlisc	11	15	in	in	ADP
cord-000079-533xlisc	11	16	clinical	clinical	ADJ
cord-000079-533xlisc	11	17	therapy	therapy	NOUN
cord-000079-533xlisc	11	18	for	for	ADP
cord-000079-533xlisc	11	19	gbm	gbm	PROPN
cord-000079-533xlisc	11	20	and	and	CCONJ
cord-000079-533xlisc	11	21	thus	thus	ADV
cord-000079-533xlisc	11	22	confirms	confirm	VERB
cord-000079-533xlisc	11	23	the	the	DET
cord-000079-533xlisc	11	24	high	high	ADJ
cord-000079-533xlisc	11	25	reproducibility	reproducibility	NOUN
cord-000079-533xlisc	11	26	of	of	ADP
cord-000079-533xlisc	11	27	the	the	DET
cord-000079-533xlisc	11	28	invasive	invasive	ADJ
cord-000079-533xlisc	11	29	glioma	glioma	NOUN
cord-000079-533xlisc	11	30	animal	animal	NOUN
cord-000079-533xlisc	11	31	model	model	NOUN
cord-000079-533xlisc	11	32	for	for	ADP
cord-000079-533xlisc	11	33	translational	translational	ADJ
cord-000079-533xlisc	11	34	research	research	NOUN
cord-000079-533xlisc	11	35	.	.	PUNCT
cord-000079-533xlisc	12	1	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	12	2	is	be	AUX
cord-000079-533xlisc	12	3	the	the	DET
cord-000079-533xlisc	12	4	most	most	ADV
cord-000079-533xlisc	12	5	frequent	frequent	ADJ
cord-000079-533xlisc	12	6	and	and	CCONJ
cord-000079-533xlisc	12	7	most	most	ADV
cord-000079-533xlisc	12	8	malignant	malignant	ADJ
cord-000079-533xlisc	12	9	primary	primary	ADJ
cord-000079-533xlisc	12	10	brain	brain	NOUN
cord-000079-533xlisc	12	11	tumor	tumor	NOUN
cord-000079-533xlisc	12	12	.	.	PUNCT
cord-000079-533xlisc	13	1	despite	despite	SCONJ
cord-000079-533xlisc	13	2	advances	advance	NOUN
cord-000079-533xlisc	13	3	in	in	ADP
cord-000079-533xlisc	13	4	neurosurgery	neurosurgery	NOUN
cord-000079-533xlisc	13	5	,	,	PUNCT
cord-000079-533xlisc	13	6	radiation	radiation	NOUN
cord-000079-533xlisc	13	7	and	and	CCONJ
cord-000079-533xlisc	13	8	chemotherapy	chemotherapy	NOUN
cord-000079-533xlisc	13	9	,	,	PUNCT
cord-000079-533xlisc	13	10	the	the	DET
cord-000079-533xlisc	13	11	prognosis	prognosis	NOUN
cord-000079-533xlisc	13	12	of	of	ADP
cord-000079-533xlisc	13	13	patients	patient	NOUN
cord-000079-533xlisc	13	14	remains	remain	VERB
cord-000079-533xlisc	13	15	poor	poor	ADJ
cord-000079-533xlisc	13	16	with	with	ADP
cord-000079-533xlisc	13	17	a	a	DET
cord-000079-533xlisc	13	18	median	median	ADJ
cord-000079-533xlisc	13	19	survival	survival	NOUN
cord-000079-533xlisc	13	20	of	of	ADP
cord-000079-533xlisc	13	21	14	14	NUM
cord-000079-533xlisc	13	22	months	month	NOUN
cord-000079-533xlisc	13	23	[	[	X
cord-000079-533xlisc	13	24	1	1	NUM
cord-000079-533xlisc	13	25	]	]	PUNCT
cord-000079-533xlisc	13	26	.	.	PUNCT
cord-000079-533xlisc	14	1	a	a	DET
cord-000079-533xlisc	14	2	major	major	ADJ
cord-000079-533xlisc	14	3	drawback	drawback	NOUN
cord-000079-533xlisc	14	4	in	in	ADP
cord-000079-533xlisc	14	5	translational	translational	ADJ
cord-000079-533xlisc	14	6	brain	brain	NOUN
cord-000079-533xlisc	14	7	cancer	cancer	NOUN
cord-000079-533xlisc	14	8	research	research	NOUN
cord-000079-533xlisc	14	9	has	have	AUX
cord-000079-533xlisc	14	10	been	be	AUX
cord-000079-533xlisc	14	11	the	the	DET
cord-000079-533xlisc	14	12	lack	lack	NOUN
cord-000079-533xlisc	14	13	of	of	ADP
cord-000079-533xlisc	14	14	suitable	suitable	ADJ
cord-000079-533xlisc	14	15	animal	animal	NOUN
cord-000079-533xlisc	14	16	models	model	NOUN
cord-000079-533xlisc	14	17	.	.	PUNCT
cord-000079-533xlisc	15	1	syngeneic	syngeneic	VERB
cord-000079-533xlisc	15	2	-	-	PUNCT
cord-000079-533xlisc	15	3	or	or	CCONJ
cord-000079-533xlisc	15	4	xenograft	xenograft	PROPN
cord-000079-533xlisc	15	5	tumors	tumor	NOUN
cord-000079-533xlisc	15	6	based	base	VERB
cord-000079-533xlisc	15	7	on	on	ADP
cord-000079-533xlisc	15	8	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	15	9	cell	cell	NOUN
cord-000079-533xlisc	15	10	lines	line	NOUN
cord-000079-533xlisc	15	11	cultured	culture	VERB
cord-000079-533xlisc	15	12	as	as	SCONJ
cord-000079-533xlisc	15	13	monolayers	monolayer	NOUN
cord-000079-533xlisc	15	14	grow	grow	VERB
cord-000079-533xlisc	15	15	as	as	SCONJ
cord-000079-533xlisc	15	16	circumscribed	circumscribe	VERB
cord-000079-533xlisc	15	17	and	and	CCONJ
cord-000079-533xlisc	15	18	highly	highly	ADV
cord-000079-533xlisc	15	19	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	15	20	lesions	lesion	NOUN
cord-000079-533xlisc	15	21	in	in	ADP
cord-000079-533xlisc	15	22	vivo	vivo	NOUN
cord-000079-533xlisc	16	1	[	[	X
cord-000079-533xlisc	16	2	2	2	NUM
cord-000079-533xlisc	16	3	]	]	PUNCT
cord-000079-533xlisc	16	4	,	,	PUNCT
cord-000079-533xlisc	16	5	lacking	lack	VERB
cord-000079-533xlisc	16	6	the	the	DET
cord-000079-533xlisc	16	7	invasive	invasive	ADJ
cord-000079-533xlisc	16	8	tumor	tumor	NOUN
cord-000079-533xlisc	16	9	cells	cell	NOUN
cord-000079-533xlisc	16	10	,	,	PUNCT
cord-000079-533xlisc	16	11	which	which	PRON
cord-000079-533xlisc	16	12	represent	represent	VERB
cord-000079-533xlisc	16	13	an	an	DET
cord-000079-533xlisc	16	14	important	important	ADJ
cord-000079-533xlisc	16	15	feature	feature	NOUN
cord-000079-533xlisc	16	16	of	of	ADP
cord-000079-533xlisc	16	17	human	human	ADJ
cord-000079-533xlisc	16	18	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	16	19	.	.	PUNCT
cord-000079-533xlisc	17	1	the	the	DET
cord-000079-533xlisc	17	2	invasive	invasive	ADJ
cord-000079-533xlisc	17	3	cells	cell	NOUN
cord-000079-533xlisc	17	4	migrate	migrate	VERB
cord-000079-533xlisc	17	5	away	away	ADV
cord-000079-533xlisc	17	6	from	from	ADP
cord-000079-533xlisc	17	7	the	the	DET
cord-000079-533xlisc	17	8	initial	initial	ADJ
cord-000079-533xlisc	17	9	tumor	tumor	NOUN
cord-000079-533xlisc	17	10	mass	mass	NOUN
cord-000079-533xlisc	17	11	and	and	CCONJ
cord-000079-533xlisc	17	12	can	can	AUX
cord-000079-533xlisc	17	13	cause	cause	VERB
cord-000079-533xlisc	17	14	recurrent	recurrent	ADJ
cord-000079-533xlisc	17	15	tumors	tumor	NOUN
cord-000079-533xlisc	17	16	in	in	ADP
cord-000079-533xlisc	17	17	different	different	ADJ
cord-000079-533xlisc	17	18	regions	region	NOUN
cord-000079-533xlisc	17	19	of	of	ADP
cord-000079-533xlisc	17	20	the	the	DET
cord-000079-533xlisc	17	21	brain	brain	NOUN
cord-000079-533xlisc	17	22	.	.	PUNCT
cord-000079-533xlisc	18	1	thus	thus	ADV
cord-000079-533xlisc	18	2	,	,	PUNCT
cord-000079-533xlisc	18	3	these	these	DET
cord-000079-533xlisc	18	4	cells	cell	NOUN
cord-000079-533xlisc	18	5	represent	represent	VERB
cord-000079-533xlisc	18	6	a	a	DET
cord-000079-533xlisc	18	7	major	major	ADJ
cord-000079-533xlisc	18	8	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	18	9	target	target	NOUN
cord-000079-533xlisc	18	10	.	.	PUNCT
cord-000079-533xlisc	19	1	a	a	DET
cord-000079-533xlisc	19	2	recently	recently	ADV
cord-000079-533xlisc	19	3	established	establish	VERB
cord-000079-533xlisc	19	4	model	model	NOUN
cord-000079-533xlisc	19	5	in	in	ADP
cord-000079-533xlisc	19	6	which	which	PRON
cord-000079-533xlisc	19	7	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	19	8	biopsybased	biopsybase	VERB
cord-000079-533xlisc	19	9	spheroids	spheroid	NOUN
cord-000079-533xlisc	19	10	are	be	AUX
cord-000079-533xlisc	19	11	serially	serially	ADV
cord-000079-533xlisc	19	12	passaged	passage	VERB
cord-000079-533xlisc	19	13	in	in	ADP
cord-000079-533xlisc	19	14	the	the	DET
cord-000079-533xlisc	19	15	brains	brain	NOUN
cord-000079-533xlisc	19	16	of	of	ADP
cord-000079-533xlisc	19	17	nude	nude	ADJ
cord-000079-533xlisc	19	18	rats	rat	NOUN
cord-000079-533xlisc	19	19	shows	show	VERB
cord-000079-533xlisc	19	20	highly	highly	ADV
cord-000079-533xlisc	19	21	invasive	invasive	ADJ
cord-000079-533xlisc	19	22	and	and	CCONJ
cord-000079-533xlisc	19	23	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	19	24	features	feature	NOUN
cord-000079-533xlisc	19	25	[	[	X
cord-000079-533xlisc	19	26	3	3	NUM
cord-000079-533xlisc	19	27	]	]	PUNCT
cord-000079-533xlisc	19	28	.	.	PUNCT
cord-000079-533xlisc	20	1	therefore	therefore	ADV
cord-000079-533xlisc	20	2	,	,	PUNCT
cord-000079-533xlisc	20	3	this	this	DET
cord-000079-533xlisc	20	4	model	model	NOUN
cord-000079-533xlisc	20	5	is	be	AUX
cord-000079-533xlisc	20	6	well	well	ADV
cord-000079-533xlisc	20	7	suited	suited	ADJ
cord-000079-533xlisc	20	8	for	for	ADP
cord-000079-533xlisc	20	9	the	the	DET
cord-000079-533xlisc	20	10	study	study	NOUN
cord-000079-533xlisc	20	11	of	of	ADP
cord-000079-533xlisc	20	12	new	new	ADJ
cord-000079-533xlisc	20	13	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	20	14	strategies	strategy	NOUN
cord-000079-533xlisc	20	15	.	.	PUNCT
cord-000079-533xlisc	21	1	still	still	ADV
cord-000079-533xlisc	21	2	,	,	PUNCT
cord-000079-533xlisc	21	3	reports	report	NOUN
cord-000079-533xlisc	21	4	using	use	VERB
cord-000079-533xlisc	21	5	this	this	PRON
cord-000079-533xlisc	21	6	or	or	CCONJ
cord-000079-533xlisc	21	7	other	other	ADJ
cord-000079-533xlisc	21	8	clinically	clinically	ADV
cord-000079-533xlisc	21	9	relevant	relevant	ADJ
cord-000079-533xlisc	21	10	models	model	NOUN
cord-000079-533xlisc	21	11	for	for	ADP
cord-000079-533xlisc	21	12	experimental	experimental	ADJ
cord-000079-533xlisc	21	13	therapy	therapy	NOUN
cord-000079-533xlisc	21	14	are	be	AUX
cord-000079-533xlisc	21	15	scarce	scarce	ADJ
cord-000079-533xlisc	21	16	.	.	PUNCT
cord-000079-533xlisc	22	1	recently	recently	ADV
cord-000079-533xlisc	22	2	,	,	PUNCT
cord-000079-533xlisc	22	3	we	we	PRON
cord-000079-533xlisc	22	4	analyzed	analyze	VERB
cord-000079-533xlisc	22	5	the	the	DET
cord-000079-533xlisc	22	6	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	22	7	potential	potential	NOUN
cord-000079-533xlisc	22	8	of	of	ADP
cord-000079-533xlisc	22	9	the	the	DET
cord-000079-533xlisc	22	10	hsv-1	hsv-1	PUNCT
cord-000079-533xlisc	22	11	-	-	PUNCT
cord-000079-533xlisc	22	12	based	base	VERB
cord-000079-533xlisc	22	13	oncolytic	oncolytic	ADJ
cord-000079-533xlisc	22	14	herpes	herpe	NOUN
cord-000079-533xlisc	22	15	vector	vector	NOUN
cord-000079-533xlisc	22	16	g207	g207	PROPN
cord-000079-533xlisc	22	17	in	in	ADP
cord-000079-533xlisc	22	18	the	the	DET
cord-000079-533xlisc	22	19	biopsy	biopsy	ADJ
cord-000079-533xlisc	22	20	spheroid	spheroid	NOUN
cord-000079-533xlisc	22	21	-	-	PUNCT
cord-000079-533xlisc	22	22	based	base	VERB
cord-000079-533xlisc	22	23	gbm	gbm	PROPN
cord-000079-533xlisc	22	24	model	model	NOUN
cord-000079-533xlisc	22	25	.	.	PUNCT
cord-000079-533xlisc	23	1	the	the	DET
cord-000079-533xlisc	23	2	tumor	tumor	NOUN
cord-000079-533xlisc	23	3	volume	volume	NOUN
cord-000079-533xlisc	23	4	in	in	ADP
cord-000079-533xlisc	23	5	treated	treat	VERB
cord-000079-533xlisc	23	6	animals	animal	NOUN
cord-000079-533xlisc	23	7	was	be	AUX
cord-000079-533xlisc	23	8	reduced	reduce	VERB
cord-000079-533xlisc	23	9	compared	compare	VERB
cord-000079-533xlisc	23	10	to	to	ADP
cord-000079-533xlisc	23	11	control	control	NOUN
cord-000079-533xlisc	23	12	groups	group	NOUN
cord-000079-533xlisc	23	13	,	,	PUNCT
cord-000079-533xlisc	23	14	but	but	CCONJ
cord-000079-533xlisc	23	15	there	there	PRON
cord-000079-533xlisc	23	16	was	be	VERB
cord-000079-533xlisc	23	17	no	no	DET
cord-000079-533xlisc	23	18	significant	significant	ADJ
cord-000079-533xlisc	23	19	survival	survival	NOUN
cord-000079-533xlisc	23	20	advantage	advantage	NOUN
cord-000079-533xlisc	23	21	[	[	X
cord-000079-533xlisc	23	22	4	4	NUM
cord-000079-533xlisc	23	23	]	]	PUNCT
cord-000079-533xlisc	23	24	.	.	PUNCT
cord-000079-533xlisc	24	1	in	in	ADP
cord-000079-533xlisc	24	2	contrast	contrast	NOUN
cord-000079-533xlisc	24	3	,	,	PUNCT
cord-000079-533xlisc	24	4	the	the	DET
cord-000079-533xlisc	24	5	same	same	ADJ
cord-000079-533xlisc	24	6	therapy	therapy	NOUN
cord-000079-533xlisc	24	7	was	be	AUX
cord-000079-533xlisc	24	8	more	more	ADV
cord-000079-533xlisc	24	9	effective	effective	ADJ
cord-000079-533xlisc	24	10	in	in	ADP
cord-000079-533xlisc	24	11	a	a	DET
cord-000079-533xlisc	24	12	cell	cell	NOUN
cord-000079-533xlisc	24	13	line	line	NOUN
cord-000079-533xlisc	24	14	-	-	PUNCT
cord-000079-533xlisc	24	15	based	base	VERB
cord-000079-533xlisc	24	16	animal	animal	NOUN
cord-000079-533xlisc	24	17	model	model	NOUN
cord-000079-533xlisc	24	18	[	[	X
cord-000079-533xlisc	24	19	5	5	NUM
cord-000079-533xlisc	24	20	]	]	PUNCT
cord-000079-533xlisc	24	21	and	and	CCONJ
cord-000079-533xlisc	24	22	as	as	ADP
cord-000079-533xlisc	24	23	a	a	DET
cord-000079-533xlisc	24	24	result	result	NOUN
cord-000079-533xlisc	24	25	is	be	AUX
cord-000079-533xlisc	24	26	currently	currently	ADV
cord-000079-533xlisc	24	27	investigated	investigate	VERB
cord-000079-533xlisc	24	28	in	in	ADP
cord-000079-533xlisc	24	29	a	a	DET
cord-000079-533xlisc	24	30	phase	phase	NOUN
cord-000079-533xlisc	24	31	i	i	NOUN
cord-000079-533xlisc	24	32	/	/	SYM
cord-000079-533xlisc	24	33	ii	ii	PROPN
cord-000079-533xlisc	24	34	clinical	clinical	ADJ
cord-000079-533xlisc	24	35	study	study	NOUN
cord-000079-533xlisc	24	36	[	[	PUNCT
cord-000079-533xlisc	24	37	6	6	NUM
cord-000079-533xlisc	24	38	]	]	PUNCT
cord-000079-533xlisc	24	39	.	.	PUNCT
cord-000079-533xlisc	25	1	in	in	ADP
cord-000079-533xlisc	25	2	the	the	DET
cord-000079-533xlisc	25	3	present	present	ADJ
cord-000079-533xlisc	25	4	investigation	investigation	NOUN
cord-000079-533xlisc	25	5	we	we	PRON
cord-000079-533xlisc	25	6	used	use	VERB
cord-000079-533xlisc	25	7	the	the	DET
cord-000079-533xlisc	25	8	invasive	invasive	ADJ
cord-000079-533xlisc	25	9	xenograft	xenograft	ADJ
cord-000079-533xlisc	25	10	model	model	NOUN
cord-000079-533xlisc	25	11	to	to	PART
cord-000079-533xlisc	25	12	evaluate	evaluate	VERB
cord-000079-533xlisc	25	13	transduction	transduction	NOUN
cord-000079-533xlisc	25	14	and	and	CCONJ
cord-000079-533xlisc	25	15	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	25	16	efficacy	efficacy	NOUN
cord-000079-533xlisc	25	17	of	of	ADP
cord-000079-533xlisc	25	18	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	25	19	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	25	20	vectors	vector	NOUN
cord-000079-533xlisc	25	21	.	.	PUNCT
cord-000079-533xlisc	26	1	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	26	2	vectors	vector	NOUN
cord-000079-533xlisc	26	3	derived	derive	VERB
cord-000079-533xlisc	26	4	from	from	ADP
cord-000079-533xlisc	26	5	the	the	DET
cord-000079-533xlisc	26	6	moloney	moloney	PROPN
cord-000079-533xlisc	26	7	murine	murine	NOUN
cord-000079-533xlisc	26	8	leukemia	leukemia	NOUN
cord-000079-533xlisc	26	9	virus	virus	NOUN
cord-000079-533xlisc	26	10	(	(	PUNCT
cord-000079-533xlisc	26	11	mmlv	mmlv	PROPN
cord-000079-533xlisc	26	12	)	)	PUNCT
cord-000079-533xlisc	26	13	have	have	AUX
cord-000079-533xlisc	26	14	been	be	AUX
cord-000079-533xlisc	26	15	the	the	DET
cord-000079-533xlisc	26	16	most	most	ADV
cord-000079-533xlisc	26	17	frequently	frequently	ADV
cord-000079-533xlisc	26	18	used	use	VERB
cord-000079-533xlisc	26	19	retroviruses	retrovirus	NOUN
cord-000079-533xlisc	26	20	for	for	ADP
cord-000079-533xlisc	26	21	gene	gene	NOUN
cord-000079-533xlisc	26	22	therapy	therapy	NOUN
cord-000079-533xlisc	26	23	of	of	ADP
cord-000079-533xlisc	26	24	brain	brain	NOUN
cord-000079-533xlisc	26	25	tumors	tumor	NOUN
cord-000079-533xlisc	26	26	[	[	X
cord-000079-533xlisc	26	27	7	7	NUM
cord-000079-533xlisc	26	28	]	]	PUNCT
cord-000079-533xlisc	26	29	[	[	X
cord-000079-533xlisc	26	30	8	8	NUM
cord-000079-533xlisc	26	31	]	]	PUNCT
cord-000079-533xlisc	26	32	[	[	X
cord-000079-533xlisc	26	33	9	9	NUM
cord-000079-533xlisc	26	34	]	]	PUNCT
cord-000079-533xlisc	26	35	[	[	X
cord-000079-533xlisc	26	36	10	10	NUM
cord-000079-533xlisc	26	37	]	]	PUNCT
cord-000079-533xlisc	26	38	.	.	PUNCT
cord-000079-533xlisc	27	1	however	however	ADV
cord-000079-533xlisc	27	2	,	,	PUNCT
cord-000079-533xlisc	27	3	despite	despite	SCONJ
cord-000079-533xlisc	27	4	promising	promise	VERB
cord-000079-533xlisc	27	5	results	result	NOUN
cord-000079-533xlisc	27	6	in	in	ADP
cord-000079-533xlisc	27	7	animal	animal	NOUN
cord-000079-533xlisc	27	8	models	model	NOUN
cord-000079-533xlisc	27	9	,	,	PUNCT
cord-000079-533xlisc	27	10	clinical	clinical	ADJ
cord-000079-533xlisc	27	11	trials	trial	NOUN
cord-000079-533xlisc	27	12	using	use	VERB
cord-000079-533xlisc	27	13	retroviral	retroviral	ADJ
cord-000079-533xlisc	27	14	vector	vector	NOUN
cord-000079-533xlisc	27	15	supernatants	supernatant	NOUN
cord-000079-533xlisc	27	16	or	or	CCONJ
cord-000079-533xlisc	27	17	retroviral	retroviral	ADJ
cord-000079-533xlisc	27	18	packaging	packaging	NOUN
cord-000079-533xlisc	27	19	cells	cell	NOUN
cord-000079-533xlisc	27	20	have	have	AUX
cord-000079-533xlisc	27	21	failed	fail	VERB
cord-000079-533xlisc	27	22	[	[	X
cord-000079-533xlisc	27	23	11	11	NUM
cord-000079-533xlisc	27	24	]	]	PUNCT
cord-000079-533xlisc	27	25	[	[	X
cord-000079-533xlisc	27	26	12	12	NUM
cord-000079-533xlisc	27	27	]	]	PUNCT
cord-000079-533xlisc	27	28	[	[	X
cord-000079-533xlisc	27	29	13	13	NUM
cord-000079-533xlisc	27	30	]	]	PUNCT
cord-000079-533xlisc	27	31	.	.	PUNCT
cord-000079-533xlisc	28	1	one	one	NUM
cord-000079-533xlisc	28	2	major	major	ADJ
cord-000079-533xlisc	28	3	drawback	drawback	NOUN
cord-000079-533xlisc	28	4	of	of	ADP
cord-000079-533xlisc	28	5	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	28	6	vectors	vector	NOUN
cord-000079-533xlisc	28	7	is	be	AUX
cord-000079-533xlisc	28	8	the	the	DET
cord-000079-533xlisc	28	9	exclusive	exclusive	ADJ
cord-000079-533xlisc	28	10	transduction	transduction	NOUN
cord-000079-533xlisc	28	11	of	of	ADP
cord-000079-533xlisc	28	12	dividing	divide	VERB
cord-000079-533xlisc	28	13	cells	cell	NOUN
cord-000079-533xlisc	28	14	,	,	PUNCT
cord-000079-533xlisc	28	15	since	since	SCONJ
cord-000079-533xlisc	28	16	in	in	ADP
cord-000079-533xlisc	28	17	human	human	ADJ
cord-000079-533xlisc	28	18	gliomas	glioma	NOUN
cord-000079-533xlisc	28	19	,	,	PUNCT
cord-000079-533xlisc	28	20	the	the	DET
cord-000079-533xlisc	28	21	majority	majority	NOUN
cord-000079-533xlisc	28	22	of	of	ADP
cord-000079-533xlisc	28	23	tumor	tumor	NOUN
cord-000079-533xlisc	28	24	cells	cell	NOUN
cord-000079-533xlisc	28	25	do	do	AUX
cord-000079-533xlisc	28	26	not	not	PART
cord-000079-533xlisc	28	27	divide	divide	VERB
cord-000079-533xlisc	28	28	within	within	ADP
cord-000079-533xlisc	28	29	a	a	DET
cord-000079-533xlisc	28	30	given	give	VERB
cord-000079-533xlisc	28	31	treatment	treatment	NOUN
cord-000079-533xlisc	28	32	window	window	NOUN
cord-000079-533xlisc	28	33	.	.	PUNCT
cord-000079-533xlisc	29	1	therefore	therefore	ADV
cord-000079-533xlisc	29	2	,	,	PUNCT
cord-000079-533xlisc	29	3	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	29	4	vectors	vector	NOUN
cord-000079-533xlisc	29	5	with	with	ADP
cord-000079-533xlisc	29	6	their	their	PRON
cord-000079-533xlisc	29	7	ability	ability	NOUN
cord-000079-533xlisc	29	8	to	to	PART
cord-000079-533xlisc	29	9	also	also	ADV
cord-000079-533xlisc	29	10	transduce	transduce	VERB
cord-000079-533xlisc	29	11	non	non	ADJ
cord-000079-533xlisc	29	12	-	-	ADJ
cord-000079-533xlisc	29	13	dividing	dividing	ADJ
cord-000079-533xlisc	29	14	cells	cell	NOUN
cord-000079-533xlisc	29	15	are	be	AUX
cord-000079-533xlisc	29	16	attractive	attractive	ADJ
cord-000079-533xlisc	29	17	candidates	candidate	NOUN
cord-000079-533xlisc	29	18	for	for	ADP
cord-000079-533xlisc	29	19	the	the	DET
cord-000079-533xlisc	29	20	treatment	treatment	NOUN
cord-000079-533xlisc	29	21	of	of	ADP
cord-000079-533xlisc	29	22	brain	brain	NOUN
cord-000079-533xlisc	29	23	cancer	cancer	NOUN
cord-000079-533xlisc	29	24	.	.	PUNCT
cord-000079-533xlisc	30	1	in	in	ADP
cord-000079-533xlisc	30	2	previous	previous	ADJ
cord-000079-533xlisc	30	3	studies	study	NOUN
cord-000079-533xlisc	30	4	,	,	PUNCT
cord-000079-533xlisc	30	5	we	we	PRON
cord-000079-533xlisc	30	6	have	have	AUX
cord-000079-533xlisc	30	7	developed	develop	VERB
cord-000079-533xlisc	30	8	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	30	9	and	and	CCONJ
cord-000079-533xlisc	30	10	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	30	11	vectors	vector	NOUN
cord-000079-533xlisc	30	12	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	30	13	with	with	ADP
cord-000079-533xlisc	30	14	the	the	DET
cord-000079-533xlisc	30	15	glycoproteins	glycoprotein	NOUN
cord-000079-533xlisc	30	16	(	(	PUNCT
cord-000079-533xlisc	30	17	gp	gp	PROPN
cord-000079-533xlisc	30	18	)	)	PUNCT
cord-000079-533xlisc	30	19	of	of	ADP
cord-000079-533xlisc	30	20	the	the	DET
cord-000079-533xlisc	30	21	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	30	22	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	30	23	virus	virus	NOUN
cord-000079-533xlisc	30	24	(	(	PUNCT
cord-000079-533xlisc	30	25	lcmv	lcmv	PROPN
cord-000079-533xlisc	30	26	)	)	PUNCT
cord-000079-533xlisc	31	1	[	[	PUNCT
cord-000079-533xlisc	31	2	14	14	NUM
cord-000079-533xlisc	31	3	,	,	PUNCT
cord-000079-533xlisc	31	4	15	15	NUM
cord-000079-533xlisc	31	5	]	]	PUNCT
cord-000079-533xlisc	31	6	.	.	PUNCT
cord-000079-533xlisc	32	1	these	these	DET
cord-000079-533xlisc	32	2	vectors	vector	NOUN
cord-000079-533xlisc	32	3	have	have	VERB
cord-000079-533xlisc	32	4	a	a	DET
cord-000079-533xlisc	32	5	broad	broad	ADJ
cord-000079-533xlisc	32	6	host	host	NOUN
cord-000079-533xlisc	32	7	range	range	NOUN
cord-000079-533xlisc	32	8	and	and	CCONJ
cord-000079-533xlisc	32	9	can	can	AUX
cord-000079-533xlisc	32	10	be	be	AUX
cord-000079-533xlisc	32	11	concentrated	concentrate	VERB
cord-000079-533xlisc	32	12	by	by	ADP
cord-000079-533xlisc	32	13	ultracentrifugation	ultracentrifugation	NOUN
cord-000079-533xlisc	32	14	for	for	ADP
cord-000079-533xlisc	32	15	in	in	ADP
cord-000079-533xlisc	32	16	vivo	vivo	ADJ
cord-000079-533xlisc	32	17	applications	application	NOUN
cord-000079-533xlisc	32	18	.	.	PUNCT
cord-000079-533xlisc	33	1	in	in	ADP
cord-000079-533xlisc	33	2	addition	addition	NOUN
cord-000079-533xlisc	33	3	,	,	PUNCT
cord-000079-533xlisc	33	4	lcmv	lcmv	PROPN
cord-000079-533xlisc	33	5	-	-	PUNCT
cord-000079-533xlisc	33	6	gp	gp	PROPN
cord-000079-533xlisc	33	7	is	be	AUX
cord-000079-533xlisc	33	8	not	not	PART
cord-000079-533xlisc	33	9	cytotoxic	cytotoxic	ADJ
cord-000079-533xlisc	33	10	,	,	PUNCT
cord-000079-533xlisc	33	11	and	and	CCONJ
cord-000079-533xlisc	33	12	stable	stable	ADJ
cord-000079-533xlisc	33	13	recombinant	recombinant	ADJ
cord-000079-533xlisc	33	14	packaging	packaging	NOUN
cord-000079-533xlisc	33	15	cell	cell	NOUN
cord-000079-533xlisc	33	16	lines	line	NOUN
cord-000079-533xlisc	33	17	can	can	AUX
cord-000079-533xlisc	33	18	be	be	AUX
cord-000079-533xlisc	33	19	established	establish	VERB
cord-000079-533xlisc	33	20	[	[	PUNCT
cord-000079-533xlisc	33	21	16	16	NUM
cord-000079-533xlisc	33	22	,	,	PUNCT
cord-000079-533xlisc	33	23	17	17	NUM
cord-000079-533xlisc	33	24	]	]	PUNCT
cord-000079-533xlisc	33	25	.	.	PUNCT
cord-000079-533xlisc	34	1	recently	recently	ADV
cord-000079-533xlisc	34	2	,	,	PUNCT
cord-000079-533xlisc	34	3	we	we	PRON
cord-000079-533xlisc	34	4	showed	show	VERB
cord-000079-533xlisc	34	5	that	that	SCONJ
cord-000079-533xlisc	34	6	lentiviral	lentiviral	PROPN
cord-000079-533xlisc	34	7	lcmv	lcmv	PROPN
cord-000079-533xlisc	34	8	-	-	PUNCT
cord-000079-533xlisc	34	9	gp	gp	PROPN
cord-000079-533xlisc	34	10	pseudotypes	pseudotype	NOUN
cord-000079-533xlisc	34	11	efficiently	efficiently	ADV
cord-000079-533xlisc	34	12	delivered	deliver	VERB
cord-000079-533xlisc	34	13	transgenes	transgene	NOUN
cord-000079-533xlisc	34	14	to	to	ADP
cord-000079-533xlisc	34	15	rat	rat	NOUN
cord-000079-533xlisc	34	16	glioma	glioma	NOUN
cord-000079-533xlisc	34	17	cells	cell	NOUN
cord-000079-533xlisc	34	18	in	in	ADP
cord-000079-533xlisc	34	19	vivo	vivo	NOUN
cord-000079-533xlisc	34	20	,	,	PUNCT
cord-000079-533xlisc	34	21	while	while	SCONJ
cord-000079-533xlisc	34	22	resident	resident	ADJ
cord-000079-533xlisc	34	23	neurons	neuron	NOUN
cord-000079-533xlisc	34	24	were	be	AUX
cord-000079-533xlisc	34	25	not	not	PART
cord-000079-533xlisc	34	26	transduced	transduce	VERB
cord-000079-533xlisc	34	27	[	[	PROPN
cord-000079-533xlisc	34	28	18	18	NUM
cord-000079-533xlisc	34	29	]	]	PUNCT
cord-000079-533xlisc	34	30	.	.	PUNCT
cord-000079-533xlisc	35	1	furthermore	furthermore	ADV
cord-000079-533xlisc	35	2	,	,	PUNCT
cord-000079-533xlisc	35	3	we	we	PRON
cord-000079-533xlisc	35	4	showed	show	VERB
cord-000079-533xlisc	35	5	a	a	DET
cord-000079-533xlisc	35	6	significant	significant	ADJ
cord-000079-533xlisc	35	7	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	35	8	effect	effect	NOUN
cord-000079-533xlisc	35	9	of	of	ADP
cord-000079-533xlisc	35	10	lcmv	lcmv	PROPN
cord-000079-533xlisc	35	11	-	-	PUNCT
cord-000079-533xlisc	35	12	gp	gp	NOUN
cord-000079-533xlisc	35	13	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	35	14	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	35	15	vectors	vector	NOUN
cord-000079-533xlisc	35	16	in	in	ADP
cord-000079-533xlisc	35	17	the	the	DET
cord-000079-533xlisc	35	18	cell	cell	NOUN
cord-000079-533xlisc	35	19	-	-	PUNCT
cord-000079-533xlisc	35	20	line	line	NOUN
cord-000079-533xlisc	35	21	based	base	VERB
cord-000079-533xlisc	35	22	9l	9l	NUM
cord-000079-533xlisc	35	23	rat	rat	NOUN
cord-000079-533xlisc	35	24	glioma	glioma	NOUN
cord-000079-533xlisc	35	25	model	model	NOUN
cord-000079-533xlisc	35	26	using	use	VERB
cord-000079-533xlisc	35	27	the	the	DET
cord-000079-533xlisc	35	28	suicide	suicide	NOUN
cord-000079-533xlisc	35	29	gene	gene	NOUN
cord-000079-533xlisc	35	30	hsv-1	hsv-1	NOUN
cord-000079-533xlisc	35	31	-	-	PUNCT
cord-000079-533xlisc	35	32	tk	tk	PROPN
cord-000079-533xlisc	35	33	.	.	PROPN
cord-000079-533xlisc	35	34	vsv	vsv	PROPN
cord-000079-533xlisc	35	35	-	-	PROPN
cord-000079-533xlisc	35	36	g	g	PROPN
cord-000079-533xlisc	35	37	lentiviral	lentiviral	NOUN
cord-000079-533xlisc	35	38	pseudotypes	pseudotype	NOUN
cord-000079-533xlisc	35	39	also	also	ADV
cord-000079-533xlisc	35	40	showed	show	VERB
cord-000079-533xlisc	35	41	a	a	DET
cord-000079-533xlisc	35	42	significant	significant	ADJ
cord-000079-533xlisc	35	43	efficacy	efficacy	NOUN
cord-000079-533xlisc	35	44	,	,	PUNCT
cord-000079-533xlisc	35	45	similar	similar	ADJ
cord-000079-533xlisc	35	46	to	to	ADP
cord-000079-533xlisc	35	47	that	that	PRON
cord-000079-533xlisc	35	48	of	of	ADP
cord-000079-533xlisc	35	49	lcmv	lcmv	PROPN
cord-000079-533xlisc	35	50	pseudotypes	pseudotypes	PROPN
cord-000079-533xlisc	35	51	,	,	PUNCT
cord-000079-533xlisc	35	52	which	which	PRON
cord-000079-533xlisc	35	53	was	be	AUX
cord-000079-533xlisc	35	54	mainly	mainly	ADV
cord-000079-533xlisc	35	55	mediated	mediate	VERB
cord-000079-533xlisc	35	56	by	by	ADP
cord-000079-533xlisc	35	57	a	a	DET
cord-000079-533xlisc	35	58	bystander	bystander	NOUN
cord-000079-533xlisc	35	59	effect	effect	NOUN
cord-000079-533xlisc	35	60	of	of	ADP
cord-000079-533xlisc	35	61	transduced	transduced	ADJ
cord-000079-533xlisc	35	62	normal	normal	ADJ
cord-000079-533xlisc	35	63	brain	brain	NOUN
cord-000079-533xlisc	35	64	cells	cell	NOUN
cord-000079-533xlisc	35	65	[	[	X
cord-000079-533xlisc	35	66	19	19	NUM
cord-000079-533xlisc	35	67	]	]	PUNCT
cord-000079-533xlisc	35	68	.	.	PUNCT
cord-000079-533xlisc	36	1	in	in	ADP
cord-000079-533xlisc	36	2	the	the	DET
cord-000079-533xlisc	36	3	presented	present	VERB
cord-000079-533xlisc	36	4	work	work	NOUN
cord-000079-533xlisc	36	5	,	,	PUNCT
cord-000079-533xlisc	36	6	we	we	PRON
cord-000079-533xlisc	36	7	showed	show	VERB
cord-000079-533xlisc	36	8	that	that	SCONJ
cord-000079-533xlisc	36	9	both	both	PRON
cord-000079-533xlisc	36	10	,	,	PUNCT
cord-000079-533xlisc	36	11	vsv	vsv	PROPN
cord-000079-533xlisc	36	12	-	-	PROPN
cord-000079-533xlisc	36	13	g	g	PROPN
cord-000079-533xlisc	36	14	and	and	CCONJ
cord-000079-533xlisc	36	15	lcmv	lcmv	PROPN
cord-000079-533xlisc	36	16	-	-	PUNCT
cord-000079-533xlisc	36	17	gp	gp	NOUN
cord-000079-533xlisc	36	18	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	36	19	lentiviruses	lentiviruse	NOUN
cord-000079-533xlisc	36	20	efficiently	efficiently	ADV
cord-000079-533xlisc	36	21	transduced	transduce	VERB
cord-000079-533xlisc	36	22	human	human	ADJ
cord-000079-533xlisc	36	23	glioma	glioma	NOUN
cord-000079-533xlisc	36	24	cells	cell	NOUN
cord-000079-533xlisc	36	25	in	in	ADP
cord-000079-533xlisc	36	26	vitro	vitro	X
cord-000079-533xlisc	36	27	and	and	CCONJ
cord-000079-533xlisc	36	28	in	in	ADP
cord-000079-533xlisc	36	29	vivo	vivo	NOUN
cord-000079-533xlisc	36	30	,	,	PUNCT
cord-000079-533xlisc	36	31	whereas	whereas	SCONJ
cord-000079-533xlisc	36	32	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	36	33	transduction	transduction	NOUN
cord-000079-533xlisc	36	34	was	be	AUX
cord-000079-533xlisc	36	35	inefficient	inefficient	ADJ
cord-000079-533xlisc	36	36	.	.	PUNCT
cord-000079-533xlisc	37	1	the	the	DET
cord-000079-533xlisc	37	2	gene	gene	NOUN
cord-000079-533xlisc	37	3	transfer	transfer	NOUN
cord-000079-533xlisc	37	4	to	to	ADP
cord-000079-533xlisc	37	5	glioma	glioma	NOUN
cord-000079-533xlisc	37	6	cells	cell	NOUN
cord-000079-533xlisc	37	7	was	be	AUX
cord-000079-533xlisc	37	8	efficient	efficient	ADJ
cord-000079-533xlisc	37	9	for	for	ADP
cord-000079-533xlisc	37	10	both	both	DET
cord-000079-533xlisc	37	11	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	37	12	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	37	13	vector	vector	NOUN
cord-000079-533xlisc	37	14	types	type	NOUN
cord-000079-533xlisc	37	15	.	.	PUNCT
cord-000079-533xlisc	38	1	however	however	ADV
cord-000079-533xlisc	38	2	,	,	PUNCT
cord-000079-533xlisc	38	3	it	it	PRON
cord-000079-533xlisc	38	4	was	be	AUX
cord-000079-533xlisc	38	5	more	more	ADV
cord-000079-533xlisc	38	6	specific	specific	ADJ
cord-000079-533xlisc	38	7	using	use	VERB
cord-000079-533xlisc	38	8	lcmv	lcmv	PROPN
cord-000079-533xlisc	38	9	-	-	PUNCT
cord-000079-533xlisc	38	10	gp	gp	NOUN
cord-000079-533xlisc	38	11	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	38	12	vectors	vector	NOUN
cord-000079-533xlisc	38	13	,	,	PUNCT
cord-000079-533xlisc	38	14	as	as	SCONJ
cord-000079-533xlisc	38	15	vsv	vsv	PROPN
cord-000079-533xlisc	38	16	-	-	PROPN
cord-000079-533xlisc	38	17	g	g	PROPN
cord-000079-533xlisc	38	18	pseudotypes	pseudotype	NOUN
cord-000079-533xlisc	38	19	also	also	ADV
cord-000079-533xlisc	38	20	transduced	transduce	VERB
cord-000079-533xlisc	38	21	host	host	NOUN
cord-000079-533xlisc	38	22	brain	brain	NOUN
cord-000079-533xlisc	38	23	cells	cell	NOUN
cord-000079-533xlisc	38	24	in	in	ADP
cord-000079-533xlisc	38	25	invasive	invasive	ADJ
cord-000079-533xlisc	38	26	areas	area	NOUN
cord-000079-533xlisc	38	27	.	.	PUNCT
cord-000079-533xlisc	39	1	analysis	analysis	NOUN
cord-000079-533xlisc	39	2	of	of	ADP
cord-000079-533xlisc	39	3	transduced	transduced	ADJ
cord-000079-533xlisc	39	4	tumor	tumor	NOUN
cord-000079-533xlisc	39	5	cells	cell	NOUN
cord-000079-533xlisc	39	6	revealed	reveal	VERB
cord-000079-533xlisc	39	7	that	that	SCONJ
cord-000079-533xlisc	39	8	both	both	DET
cord-000079-533xlisc	39	9	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	39	10	vectors	vector	NOUN
cord-000079-533xlisc	39	11	targeted	target	VERB
cord-000079-533xlisc	39	12	cd133	cd133	NOUN
cord-000079-533xlisc	39	13	-	-	PUNCT
cord-000079-533xlisc	39	14	positive	positive	ADJ
cord-000079-533xlisc	39	15	as	as	ADV
cord-000079-533xlisc	39	16	well	well	ADV
cord-000079-533xlisc	39	17	as	as	ADP
cord-000079-533xlisc	39	18	cd133negative	cd133negative	PROPN
cord-000079-533xlisc	39	19	cancer	cancer	NOUN
cord-000079-533xlisc	39	20	cells	cell	NOUN
cord-000079-533xlisc	39	21	.	.	PUNCT
cord-000079-533xlisc	40	1	furthermore	furthermore	ADV
cord-000079-533xlisc	40	2	,	,	PUNCT
cord-000079-533xlisc	40	3	transduced	transduced	ADJ
cord-000079-533xlisc	40	4	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	40	5	cells	cell	NOUN
cord-000079-533xlisc	40	6	expressed	express	VERB
cord-000079-533xlisc	40	7	the	the	DET
cord-000079-533xlisc	40	8	stem	stem	NOUN
cord-000079-533xlisc	40	9	cell	cell	NOUN
cord-000079-533xlisc	40	10	markers	marker	NOUN
cord-000079-533xlisc	40	11	nestin	nestin	PROPN
cord-000079-533xlisc	40	12	and	and	CCONJ
cord-000079-533xlisc	40	13	sox2	sox2	PROPN
cord-000079-533xlisc	40	14	.	.	PUNCT
cord-000079-533xlisc	41	1	importantly	importantly	ADV
cord-000079-533xlisc	41	2	,	,	PUNCT
cord-000079-533xlisc	41	3	when	when	SCONJ
cord-000079-533xlisc	41	4	evaluated	evaluate	VERB
cord-000079-533xlisc	41	5	for	for	ADP
cord-000079-533xlisc	41	6	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	41	7	application	application	NOUN
cord-000079-533xlisc	41	8	using	use	VERB
cord-000079-533xlisc	41	9	hsv-1	hsv-1	NOUN
cord-000079-533xlisc	41	10	-	-	PUNCT
cord-000079-533xlisc	41	11	tk	tk	X
cord-000079-533xlisc	41	12	as	as	ADP
cord-000079-533xlisc	41	13	a	a	DET
cord-000079-533xlisc	41	14	transgene	transgene	NOUN
cord-000079-533xlisc	41	15	,	,	PUNCT
cord-000079-533xlisc	41	16	both	both	DET
cord-000079-533xlisc	41	17	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	41	18	vectors	vector	NOUN
cord-000079-533xlisc	41	19	mediated	mediate	VERB
cord-000079-533xlisc	41	20	complete	complete	ADJ
cord-000079-533xlisc	41	21	tumor	tumor	NOUN
cord-000079-533xlisc	41	22	regression	regression	NOUN
cord-000079-533xlisc	41	23	on	on	ADP
cord-000079-533xlisc	41	24	mri	mri	NOUN
cord-000079-533xlisc	41	25	,	,	PUNCT
cord-000079-533xlisc	41	26	resulting	result	VERB
cord-000079-533xlisc	41	27	in	in	ADP
cord-000079-533xlisc	41	28	a	a	DET
cord-000079-533xlisc	41	29	highly	highly	ADV
cord-000079-533xlisc	41	30	significant	significant	ADJ
cord-000079-533xlisc	41	31	survival	survival	NOUN
cord-000079-533xlisc	41	32	benefit	benefit	NOUN
cord-000079-533xlisc	41	33	(	(	PUNCT
cord-000079-533xlisc	41	34	p,0.001	p,0.001	NOUN
cord-000079-533xlisc	41	35	)	)	PUNCT
cord-000079-533xlisc	41	36	compared	compare	VERB
cord-000079-533xlisc	41	37	to	to	ADP
cord-000079-533xlisc	41	38	the	the	DET
cord-000079-533xlisc	41	39	control	control	NOUN
cord-000079-533xlisc	41	40	groups	group	NOUN
cord-000079-533xlisc	41	41	.	.	PUNCT
cord-000079-533xlisc	42	1	the	the	DET
cord-000079-533xlisc	42	2	collection	collection	NOUN
cord-000079-533xlisc	42	3	of	of	ADP
cord-000079-533xlisc	42	4	human	human	ADJ
cord-000079-533xlisc	42	5	biopsy	biopsy	ADJ
cord-000079-533xlisc	42	6	tissue	tissue	NOUN
cord-000079-533xlisc	42	7	was	be	AUX
cord-000079-533xlisc	42	8	approved	approve	VERB
cord-000079-533xlisc	42	9	by	by	ADP
cord-000079-533xlisc	42	10	the	the	DET
cord-000079-533xlisc	42	11	regional	regional	ADJ
cord-000079-533xlisc	42	12	ethical	ethical	ADJ
cord-000079-533xlisc	42	13	committee	committee	NOUN
cord-000079-533xlisc	42	14	.	.	PUNCT
cord-000079-533xlisc	43	1	the	the	DET
cord-000079-533xlisc	43	2	handling	handling	NOUN
cord-000079-533xlisc	43	3	of	of	ADP
cord-000079-533xlisc	43	4	the	the	DET
cord-000079-533xlisc	43	5	animals	animal	NOUN
cord-000079-533xlisc	43	6	and	and	CCONJ
cord-000079-533xlisc	43	7	the	the	DET
cord-000079-533xlisc	43	8	surgical	surgical	ADJ
cord-000079-533xlisc	43	9	procedures	procedure	NOUN
cord-000079-533xlisc	43	10	were	be	AUX
cord-000079-533xlisc	43	11	done	do	VERB
cord-000079-533xlisc	43	12	in	in	ADP
cord-000079-533xlisc	43	13	accordance	accordance	NOUN
cord-000079-533xlisc	43	14	with	with	ADP
cord-000079-533xlisc	43	15	the	the	DET
cord-000079-533xlisc	43	16	norwegian	norwegian	ADJ
cord-000079-533xlisc	43	17	animal	animal	PROPN
cord-000079-533xlisc	43	18	act	act	PROPN
cord-000079-533xlisc	43	19	and	and	CCONJ
cord-000079-533xlisc	43	20	the	the	DET
cord-000079-533xlisc	43	21	local	local	ADJ
cord-000079-533xlisc	43	22	ethical	ethical	ADJ
cord-000079-533xlisc	43	23	committee	committee	NOUN
cord-000079-533xlisc	43	24	approved	approve	VERB
cord-000079-533xlisc	43	25	the	the	DET
cord-000079-533xlisc	43	26	protocol	protocol	NOUN
cord-000079-533xlisc	43	27	.	.	PUNCT
cord-000079-533xlisc	44	1	the	the	DET
cord-000079-533xlisc	44	2	human	human	ADJ
cord-000079-533xlisc	44	3	embryonic	embryonic	NOUN
cord-000079-533xlisc	44	4	kidney	kidney	NOUN
cord-000079-533xlisc	44	5	cell	cell	NOUN
cord-000079-533xlisc	44	6	line	line	NOUN
cord-000079-533xlisc	44	7	293	293	NUM
cord-000079-533xlisc	44	8	t	t	PROPN
cord-000079-533xlisc	44	9	(	(	PUNCT
cord-000079-533xlisc	44	10	atcc	atcc	PROPN
cord-000079-533xlisc	44	11	number	number	NOUN
cord-000079-533xlisc	44	12	crl-11268	crl-11268	NOUN
cord-000079-533xlisc	44	13	)	)	PUNCT
cord-000079-533xlisc	44	14	and	and	CCONJ
cord-000079-533xlisc	44	15	the	the	DET
cord-000079-533xlisc	44	16	te671	te671	PROPN
cord-000079-533xlisc	44	17	cell	cell	NOUN
cord-000079-533xlisc	44	18	line	line	NOUN
cord-000079-533xlisc	44	19	were	be	AUX
cord-000079-533xlisc	44	20	obtained	obtain	VERB
cord-000079-533xlisc	44	21	from	from	ADP
cord-000079-533xlisc	44	22	the	the	DET
cord-000079-533xlisc	44	23	american	american	ADJ
cord-000079-533xlisc	44	24	type	type	NOUN
cord-000079-533xlisc	44	25	culture	culture	NOUN
cord-000079-533xlisc	44	26	collection	collection	NOUN
cord-000079-533xlisc	44	27	(	(	PUNCT
cord-000079-533xlisc	44	28	atcc	atcc	PROPN
cord-000079-533xlisc	44	29	,	,	PUNCT
cord-000079-533xlisc	44	30	manassas	manassas	PROPN
cord-000079-533xlisc	44	31	,	,	PUNCT
cord-000079-533xlisc	44	32	va	va	PROPN
cord-000079-533xlisc	44	33	)	)	PUNCT
cord-000079-533xlisc	44	34	and	and	CCONJ
cord-000079-533xlisc	44	35	maintained	maintain	VERB
cord-000079-533xlisc	44	36	in	in	ADP
cord-000079-533xlisc	44	37	dulbbeco	dulbbeco	PROPN
cord-000079-533xlisc	44	38	's	's	PART
cord-000079-533xlisc	44	39	modified	modified	ADJ
cord-000079-533xlisc	44	40	eagle	eagle	NOUN
cord-000079-533xlisc	44	41	medium	medium	NOUN
cord-000079-533xlisc	44	42	(	(	PUNCT
cord-000079-533xlisc	44	43	dmem	dmem	PROPN
cord-000079-533xlisc	44	44	)	)	PUNCT
cord-000079-533xlisc	44	45	supplemented	supplement	VERB
cord-000079-533xlisc	44	46	with	with	ADP
cord-000079-533xlisc	44	47	10	10	NUM
cord-000079-533xlisc	44	48	%	%	NOUN
cord-000079-533xlisc	44	49	fetal	fetal	ADJ
cord-000079-533xlisc	44	50	calf	calf	NOUN
cord-000079-533xlisc	44	51	serum	serum	NOUN
cord-000079-533xlisc	44	52	(	(	PUNCT
cord-000079-533xlisc	44	53	fcs	fc	NOUN
cord-000079-533xlisc	44	54	)	)	PUNCT
cord-000079-533xlisc	44	55	and	and	CCONJ
cord-000079-533xlisc	44	56	1	1	NUM
cord-000079-533xlisc	44	57	%	%	NOUN
cord-000079-533xlisc	44	58	glutamine	glutamine	NOUN
cord-000079-533xlisc	44	59	.	.	PUNCT
cord-000079-533xlisc	45	1	all	all	DET
cord-000079-533xlisc	45	2	cell	cell	NOUN
cord-000079-533xlisc	45	3	lines	line	NOUN
cord-000079-533xlisc	45	4	were	be	AUX
cord-000079-533xlisc	45	5	grown	grow	VERB
cord-000079-533xlisc	45	6	at	at	ADP
cord-000079-533xlisc	45	7	37uc	37uc	ADJ
cord-000079-533xlisc	45	8	in	in	ADP
cord-000079-533xlisc	45	9	a	a	DET
cord-000079-533xlisc	45	10	humidified	humidified	ADJ
cord-000079-533xlisc	45	11	atmosphere	atmosphere	NOUN
cord-000079-533xlisc	45	12	of	of	ADP
cord-000079-533xlisc	45	13	5	5	NUM
cord-000079-533xlisc	45	14	%	%	NOUN
cord-000079-533xlisc	45	15	co	co	NOUN
cord-000079-533xlisc	45	16	2	2	NUM
cord-000079-533xlisc	45	17	.	.	PUNCT
cord-000079-533xlisc	46	1	tumor	tumor	NOUN
cord-000079-533xlisc	46	2	fragments	fragment	VERB
cord-000079-533xlisc	46	3	from	from	ADP
cord-000079-533xlisc	46	4	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	46	5	multiforme	multiforme	NOUN
cord-000079-533xlisc	46	6	patients	patient	NOUN
cord-000079-533xlisc	46	7	were	be	AUX
cord-000079-533xlisc	46	8	obtained	obtain	VERB
cord-000079-533xlisc	46	9	during	during	ADP
cord-000079-533xlisc	46	10	surgery	surgery	NOUN
cord-000079-533xlisc	46	11	.	.	PUNCT
cord-000079-533xlisc	47	1	tissue	tissue	NOUN
cord-000079-533xlisc	47	2	specimens	specimen	NOUN
cord-000079-533xlisc	47	3	were	be	AUX
cord-000079-533xlisc	47	4	taken	take	VERB
cord-000079-533xlisc	47	5	from	from	ADP
cord-000079-533xlisc	47	6	viable	viable	ADJ
cord-000079-533xlisc	47	7	tumor	tumor	NOUN
cord-000079-533xlisc	47	8	areas	area	NOUN
cord-000079-533xlisc	47	9	that	that	PRON
cord-000079-533xlisc	47	10	corresponded	correspond	VERB
cord-000079-533xlisc	47	11	to	to	ADP
cord-000079-533xlisc	47	12	regions	region	NOUN
cord-000079-533xlisc	47	13	with	with	ADP
cord-000079-533xlisc	47	14	contrast	contrast	NOUN
cord-000079-533xlisc	47	15	enhancement	enhancement	NOUN
cord-000079-533xlisc	47	16	on	on	ADP
cord-000079-533xlisc	47	17	preoperative	preoperative	ADJ
cord-000079-533xlisc	47	18	mri	mri	NOUN
cord-000079-533xlisc	47	19	-	-	PUNCT
cord-000079-533xlisc	47	20	scans	scan	NOUN
cord-000079-533xlisc	47	21	.	.	PUNCT
cord-000079-533xlisc	48	1	the	the	DET
cord-000079-533xlisc	48	2	specimens	specimen	NOUN
cord-000079-533xlisc	48	3	were	be	AUX
cord-000079-533xlisc	48	4	transferred	transfer	VERB
cord-000079-533xlisc	48	5	to	to	PART
cord-000079-533xlisc	48	6	test	test	NOUN
cord-000079-533xlisc	48	7	tubes	tube	NOUN
cord-000079-533xlisc	48	8	containing	contain	VERB
cord-000079-533xlisc	48	9	complete	complete	ADJ
cord-000079-533xlisc	48	10	growth	growth	NOUN
cord-000079-533xlisc	48	11	medium	medium	NOUN
cord-000079-533xlisc	48	12	,	,	PUNCT
cord-000079-533xlisc	48	13	and	and	CCONJ
cord-000079-533xlisc	48	14	spheroids	spheroid	NOUN
cord-000079-533xlisc	48	15	were	be	AUX
cord-000079-533xlisc	48	16	prepared	prepare	VERB
cord-000079-533xlisc	48	17	as	as	SCONJ
cord-000079-533xlisc	48	18	previously	previously	ADV
cord-000079-533xlisc	48	19	described	describe	VERB
cord-000079-533xlisc	48	20	[	[	X
cord-000079-533xlisc	48	21	20	20	NUM
cord-000079-533xlisc	48	22	]	]	PUNCT
cord-000079-533xlisc	48	23	.	.	PUNCT
cord-000079-533xlisc	49	1	the	the	DET
cord-000079-533xlisc	49	2	same	same	ADJ
cord-000079-533xlisc	49	3	method	method	NOUN
cord-000079-533xlisc	49	4	was	be	AUX
cord-000079-533xlisc	49	5	applied	apply	VERB
cord-000079-533xlisc	49	6	for	for	ADP
cord-000079-533xlisc	49	7	tumor	tumor	NOUN
cord-000079-533xlisc	49	8	material	material	NOUN
cord-000079-533xlisc	49	9	passaged	passage	VERB
cord-000079-533xlisc	49	10	in	in	ADP
cord-000079-533xlisc	49	11	nude	nude	ADJ
cord-000079-533xlisc	49	12	rats	rat	NOUN
cord-000079-533xlisc	49	13	.	.	PUNCT
cord-000079-533xlisc	50	1	briefly	briefly	ADV
cord-000079-533xlisc	50	2	,	,	PUNCT
cord-000079-533xlisc	50	3	tissue	tissue	NOUN
cord-000079-533xlisc	50	4	samples	sample	NOUN
cord-000079-533xlisc	50	5	were	be	AUX
cord-000079-533xlisc	50	6	minced	mince	VERB
cord-000079-533xlisc	50	7	into	into	ADP
cord-000079-533xlisc	50	8	,	,	PUNCT
cord-000079-533xlisc	50	9	0.5	0.5	NUM
cord-000079-533xlisc	50	10	mm	mm	NOUN
cord-000079-533xlisc	50	11	fragments	fragment	NOUN
cord-000079-533xlisc	50	12	and	and	CCONJ
cord-000079-533xlisc	50	13	placed	place	VERB
cord-000079-533xlisc	50	14	into	into	ADP
cord-000079-533xlisc	50	15	80	80	NUM
cord-000079-533xlisc	50	16	cm	cm	NOUN
cord-000079-533xlisc	50	17	2	2	NUM
cord-000079-533xlisc	50	18	tissue	tissue	NOUN
cord-000079-533xlisc	50	19	culture	culture	NOUN
cord-000079-533xlisc	50	20	flasks	flask	NOUN
cord-000079-533xlisc	50	21	(	(	PUNCT
cord-000079-533xlisc	50	22	nunc	nunc	X
cord-000079-533xlisc	50	23	,	,	PUNCT
cord-000079-533xlisc	50	24	roskilde	roskilde	ADJ
cord-000079-533xlisc	50	25	,	,	PUNCT
cord-000079-533xlisc	50	26	denmark	denmark	PROPN
cord-000079-533xlisc	50	27	)	)	PUNCT
cord-000079-533xlisc	50	28	base	base	NOUN
cord-000079-533xlisc	50	29	-	-	PUNCT
cord-000079-533xlisc	50	30	coated	coat	VERB
cord-000079-533xlisc	50	31	with	with	ADP
cord-000079-533xlisc	50	32	0.75	0.75	NUM
cord-000079-533xlisc	50	33	%	%	NOUN
cord-000079-533xlisc	50	34	agar	agar	NOUN
cord-000079-533xlisc	50	35	(	(	PUNCT
cord-000079-533xlisc	50	36	difco	difco	PROPN
cord-000079-533xlisc	50	37	,	,	PUNCT
cord-000079-533xlisc	50	38	detroit	detroit	PROPN
cord-000079-533xlisc	50	39	,	,	PUNCT
cord-000079-533xlisc	50	40	mi	mi	PROPN
cord-000079-533xlisc	50	41	)	)	PUNCT
cord-000079-533xlisc	50	42	.	.	PUNCT
cord-000079-533xlisc	51	1	the	the	DET
cord-000079-533xlisc	51	2	spheroids	spheroid	NOUN
cord-000079-533xlisc	51	3	were	be	AUX
cord-000079-533xlisc	51	4	maintained	maintain	VERB
cord-000079-533xlisc	51	5	in	in	ADP
cord-000079-533xlisc	51	6	a	a	DET
cord-000079-533xlisc	51	7	standard	standard	ADJ
cord-000079-533xlisc	51	8	tissue	tissue	NOUN
cord-000079-533xlisc	51	9	culture	culture	NOUN
cord-000079-533xlisc	51	10	incubator	incubator	NOUN
cord-000079-533xlisc	51	11	with	with	ADP
cord-000079-533xlisc	51	12	5	5	NUM
cord-000079-533xlisc	51	13	%	%	NOUN
cord-000079-533xlisc	51	14	co	co	NOUN
cord-000079-533xlisc	51	15	2	2	NUM
cord-000079-533xlisc	51	16	and	and	CCONJ
cord-000079-533xlisc	51	17	100	100	NUM
cord-000079-533xlisc	51	18	%	%	NOUN
cord-000079-533xlisc	51	19	relative	relative	ADJ
cord-000079-533xlisc	51	20	humidity	humidity	NOUN
cord-000079-533xlisc	51	21	at	at	ADP
cord-000079-533xlisc	51	22	37uc	37uc	NUM
cord-000079-533xlisc	51	23	.	.	PUNCT
cord-000079-533xlisc	52	1	the	the	DET
cord-000079-533xlisc	52	2	medium	medium	NOUN
cord-000079-533xlisc	52	3	was	be	AUX
cord-000079-533xlisc	52	4	changed	change	VERB
cord-000079-533xlisc	52	5	once	once	ADV
cord-000079-533xlisc	52	6	a	a	DET
cord-000079-533xlisc	52	7	week	week	NOUN
cord-000079-533xlisc	52	8	.	.	PUNCT
cord-000079-533xlisc	53	1	spheroids	spheroid	NOUN
cord-000079-533xlisc	53	2	with	with	ADP
cord-000079-533xlisc	53	3	diameters	diameter	NOUN
cord-000079-533xlisc	53	4	between	between	ADP
cord-000079-533xlisc	53	5	400	400	NUM
cord-000079-533xlisc	53	6	and	and	CCONJ
cord-000079-533xlisc	53	7	600	600	NUM
cord-000079-533xlisc	53	8	mm	mm	NOUN
cord-000079-533xlisc	53	9	were	be	AUX
cord-000079-533xlisc	53	10	selected	select	VERB
cord-000079-533xlisc	53	11	for	for	ADP
cord-000079-533xlisc	53	12	in	in	ADP
cord-000079-533xlisc	53	13	vitro	vitro	X
cord-000079-533xlisc	53	14	experiments	experiment	NOUN
cord-000079-533xlisc	53	15	and	and	CCONJ
cord-000079-533xlisc	53	16	for	for	ADP
cord-000079-533xlisc	53	17	intracerebral	intracerebral	ADJ
cord-000079-533xlisc	53	18	implantation	implantation	NOUN
cord-000079-533xlisc	53	19	.	.	PUNCT
cord-000079-533xlisc	54	1	tumors	tumor	NOUN
cord-000079-533xlisc	54	2	were	be	AUX
cord-000079-533xlisc	54	3	dissociated	dissociate	VERB
cord-000079-533xlisc	54	4	using	use	VERB
cord-000079-533xlisc	54	5	the	the	DET
cord-000079-533xlisc	54	6	neuronal	neuronal	ADJ
cord-000079-533xlisc	54	7	dissociation	dissociation	NOUN
cord-000079-533xlisc	54	8	kit	kit	NOUN
cord-000079-533xlisc	54	9	(	(	PUNCT
cord-000079-533xlisc	54	10	miltenyi	miltenyi	PROPN
cord-000079-533xlisc	54	11	,	,	PUNCT
cord-000079-533xlisc	54	12	bergisch	bergisch	PROPN
cord-000079-533xlisc	54	13	-	-	PUNCT
cord-000079-533xlisc	54	14	gladbach	gladbach	PROPN
cord-000079-533xlisc	54	15	,	,	PUNCT
cord-000079-533xlisc	54	16	germany	germany	PROPN
cord-000079-533xlisc	54	17	)	)	PUNCT
cord-000079-533xlisc	54	18	according	accord	VERB
cord-000079-533xlisc	54	19	to	to	ADP
cord-000079-533xlisc	54	20	the	the	DET
cord-000079-533xlisc	54	21	manufacturer	manufacturer	NOUN
cord-000079-533xlisc	54	22	's	's	PART
cord-000079-533xlisc	54	23	protocol	protocol	NOUN
cord-000079-533xlisc	54	24	.	.	PUNCT
cord-000079-533xlisc	55	1	cells	cell	NOUN
cord-000079-533xlisc	55	2	were	be	AUX
cord-000079-533xlisc	55	3	analyzed	analyze	VERB
cord-000079-533xlisc	55	4	and	and	CCONJ
cord-000079-533xlisc	55	5	sorted	sort	VERB
cord-000079-533xlisc	55	6	on	on	ADP
cord-000079-533xlisc	55	7	a	a	DET
cord-000079-533xlisc	55	8	moflo	moflo	PROPN
cord-000079-533xlisc	55	9	cell	cell	NOUN
cord-000079-533xlisc	55	10	sorter	sorter	NOUN
cord-000079-533xlisc	55	11	(	(	PUNCT
cord-000079-533xlisc	55	12	beckman	beckman	PROPN
cord-000079-533xlisc	55	13	coulter	coulter	PROPN
cord-000079-533xlisc	55	14	,	,	PUNCT
cord-000079-533xlisc	55	15	usa	usa	PROPN
cord-000079-533xlisc	55	16	;	;	PUNCT
cord-000079-533xlisc	55	17	former	former	ADJ
cord-000079-533xlisc	55	18	cytomation	cytomation	NOUN
cord-000079-533xlisc	55	19	,	,	PUNCT
cord-000079-533xlisc	55	20	usa	usa	PROPN
cord-000079-533xlisc	55	21	)	)	PUNCT
cord-000079-533xlisc	55	22	,	,	PUNCT
cord-000079-533xlisc	55	23	equipped	equip	VERB
cord-000079-533xlisc	55	24	with	with	ADP
cord-000079-533xlisc	55	25	a	a	DET
cord-000079-533xlisc	55	26	coherent	coherent	ADJ
cord-000079-533xlisc	55	27	enterprise	enterprise	NOUN
cord-000079-533xlisc	55	28	621	621	NUM
cord-000079-533xlisc	55	29	argon	argon	PROPN
cord-000079-533xlisc	55	30	-	-	PUNCT
cord-000079-533xlisc	55	31	ion	ion	NOUN
cord-000079-533xlisc	55	32	laser	laser	NOUN
cord-000079-533xlisc	55	33	tuned	tune	VERB
cord-000079-533xlisc	55	34	to	to	ADP
cord-000079-533xlisc	55	35	488	488	NUM
cord-000079-533xlisc	55	36	nm	nm	NOUN
cord-000079-533xlisc	55	37	(	(	PUNCT
cord-000079-533xlisc	55	38	used	use	VERB
cord-000079-533xlisc	55	39	at	at	ADP
cord-000079-533xlisc	55	40	180	180	NUM
cord-000079-533xlisc	55	41	mw	mw	NUM
cord-000079-533xlisc	55	42	)	)	PUNCT
cord-000079-533xlisc	55	43	,	,	PUNCT
cord-000079-533xlisc	55	44	and	and	CCONJ
cord-000079-533xlisc	55	45	635	635	NUM
cord-000079-533xlisc	55	46	nm	nm	NOUN
cord-000079-533xlisc	55	47	diode	diode	NOUN
cord-000079-533xlisc	55	48	(	(	PUNCT
cord-000079-533xlisc	55	49	25	25	NUM
cord-000079-533xlisc	55	50	mw	mw	NUM
cord-000079-533xlisc	55	51	)	)	PUNCT
cord-000079-533xlisc	55	52	.	.	PUNCT
cord-000079-533xlisc	56	1	two	two	NUM
cord-000079-533xlisc	56	2	mg	mg	NOUN
cord-000079-533xlisc	56	3	/	/	SYM
cord-000079-533xlisc	56	4	ml	ml	PROPN
cord-000079-533xlisc	56	5	propidium	propidium	NOUN
cord-000079-533xlisc	56	6	iodide	iodide	NOUN
cord-000079-533xlisc	56	7	-pi	-pi	PUNCT
cord-000079-533xlisc	56	8	(	(	PUNCT
cord-000079-533xlisc	56	9	molecular	molecular	ADJ
cord-000079-533xlisc	56	10	probes	probe	NOUN
cord-000079-533xlisc	56	11	)	)	PUNCT
cord-000079-533xlisc	56	12	were	be	AUX
cord-000079-533xlisc	56	13	added	add	VERB
cord-000079-533xlisc	56	14	to	to	ADP
cord-000079-533xlisc	56	15	the	the	DET
cord-000079-533xlisc	56	16	samples	sample	NOUN
cord-000079-533xlisc	56	17	before	before	ADP
cord-000079-533xlisc	56	18	flow	flow	NOUN
cord-000079-533xlisc	56	19	sorting	sort	VERB
cord-000079-533xlisc	56	20	to	to	PART
cord-000079-533xlisc	56	21	facilitate	facilitate	VERB
cord-000079-533xlisc	56	22	dead	dead	ADJ
cord-000079-533xlisc	56	23	cell	cell	NOUN
cord-000079-533xlisc	56	24	discrimination	discrimination	NOUN
cord-000079-533xlisc	56	25	.	.	PUNCT
cord-000079-533xlisc	57	1	the	the	DET
cord-000079-533xlisc	57	2	gfp	gfp	NOUN
cord-000079-533xlisc	57	3	and	and	CCONJ
cord-000079-533xlisc	57	4	pi	pi	NOUN
cord-000079-533xlisc	57	5	were	be	AUX
cord-000079-533xlisc	57	6	excited	excite	VERB
cord-000079-533xlisc	57	7	at	at	ADP
cord-000079-533xlisc	57	8	488	488	NUM
cord-000079-533xlisc	57	9	nm	nm	NOUN
cord-000079-533xlisc	57	10	and	and	CCONJ
cord-000079-533xlisc	57	11	fluorescence	fluorescence	PROPN
cord-000079-533xlisc	57	12	was	be	AUX
cord-000079-533xlisc	57	13	measured	measure	VERB
cord-000079-533xlisc	57	14	through	through	ADP
cord-000079-533xlisc	57	15	530/40	530/40	PROPN
cord-000079-533xlisc	57	16	bp	bp	PROPN
cord-000079-533xlisc	57	17	and	and	CCONJ
cord-000079-533xlisc	57	18	613/20	613/20	NUM
cord-000079-533xlisc	57	19	bp	bp	NOUN
cord-000079-533xlisc	57	20	optical	optical	ADJ
cord-000079-533xlisc	57	21	filters	filter	NOUN
cord-000079-533xlisc	57	22	(	(	PUNCT
cord-000079-533xlisc	57	23	all	all	DET
cord-000079-533xlisc	57	24	filters	filter	NOUN
cord-000079-533xlisc	57	25	from	from	ADP
cord-000079-533xlisc	57	26	omega	omega	NOUN
cord-000079-533xlisc	57	27	optical	optical	ADJ
cord-000079-533xlisc	57	28	,	,	PUNCT
cord-000079-533xlisc	57	29	brattleboro	brattleboro	PROPN
cord-000079-533xlisc	57	30	,	,	PUNCT
cord-000079-533xlisc	57	31	vt	vt	PROPN
cord-000079-533xlisc	57	32	,	,	PUNCT
cord-000079-533xlisc	57	33	usa	usa	PROPN
cord-000079-533xlisc	57	34	)	)	PUNCT
cord-000079-533xlisc	57	35	,	,	PUNCT
cord-000079-533xlisc	57	36	respectively	respectively	ADV
cord-000079-533xlisc	57	37	.	.	PUNCT
cord-000079-533xlisc	58	1	doublets	doublet	NOUN
cord-000079-533xlisc	58	2	were	be	AUX
cord-000079-533xlisc	58	3	discriminated	discriminate	VERB
cord-000079-533xlisc	58	4	using	use	VERB
cord-000079-533xlisc	58	5	a	a	DET
cord-000079-533xlisc	58	6	forward	forward	ADJ
cord-000079-533xlisc	58	7	light	light	NOUN
cord-000079-533xlisc	58	8	scatter	scatter	NOUN
cord-000079-533xlisc	58	9	(	(	PUNCT
cord-000079-533xlisc	58	10	fsc	fsc	PROPN
cord-000079-533xlisc	58	11	)	)	PUNCT
cord-000079-533xlisc	58	12	versus	versus	ADP
cord-000079-533xlisc	58	13	pulse	pulse	PROPN
cord-000079-533xlisc	58	14	width	width	NOUN
cord-000079-533xlisc	58	15	.	.	PUNCT
cord-000079-533xlisc	59	1	fl3	fl3	NOUN
cord-000079-533xlisc	59	2	channel	channel	NOUN
cord-000079-533xlisc	59	3	(	(	PUNCT
cord-000079-533xlisc	59	4	in	in	ADP
cord-000079-533xlisc	59	5	logarithmic	logarithmic	ADJ
cord-000079-533xlisc	59	6	mode	mode	NOUN
cord-000079-533xlisc	59	7	)	)	PUNCT
cord-000079-533xlisc	59	8	with	with	ADP
cord-000079-533xlisc	59	9	fsc	fsc	PROPN
cord-000079-533xlisc	59	10	were	be	AUX
cord-000079-533xlisc	59	11	used	use	VERB
cord-000079-533xlisc	59	12	to	to	PART
cord-000079-533xlisc	59	13	display	display	VERB
cord-000079-533xlisc	59	14	and	and	CCONJ
cord-000079-533xlisc	59	15	gate	gate	VERB
cord-000079-533xlisc	59	16	out	out	ADP
cord-000079-533xlisc	59	17	pi	pi	PROPN
cord-000079-533xlisc	59	18	positive	positive	ADJ
cord-000079-533xlisc	59	19	/	/	SYM
cord-000079-533xlisc	59	20	dead	dead	ADJ
cord-000079-533xlisc	59	21	cells	cell	NOUN
cord-000079-533xlisc	59	22	.	.	PUNCT
cord-000079-533xlisc	60	1	fsc	fsc	PROPN
cord-000079-533xlisc	60	2	and	and	CCONJ
cord-000079-533xlisc	60	3	side	side	NOUN
cord-000079-533xlisc	60	4	light	light	NOUN
cord-000079-533xlisc	60	5	scatter	scatter	NOUN
cord-000079-533xlisc	60	6	(	(	PUNCT
cord-000079-533xlisc	60	7	ssc	ssc	NOUN
cord-000079-533xlisc	60	8	)	)	PUNCT
cord-000079-533xlisc	60	9	signals	signal	NOUN
cord-000079-533xlisc	60	10	were	be	AUX
cord-000079-533xlisc	60	11	detected	detect	VERB
cord-000079-533xlisc	60	12	and	and	CCONJ
cord-000079-533xlisc	60	13	shown	show	VERB
cord-000079-533xlisc	60	14	in	in	ADP
cord-000079-533xlisc	60	15	linear	linear	PROPN
cord-000079-533xlisc	60	16	mode	mode	NOUN
cord-000079-533xlisc	60	17	.	.	PUNCT
cord-000079-533xlisc	61	1	gfp+	gfp+	PROPN
cord-000079-533xlisc	61	2	cells	cell	NOUN
cord-000079-533xlisc	61	3	were	be	AUX
cord-000079-533xlisc	61	4	defined	define	VERB
cord-000079-533xlisc	61	5	on	on	ADP
cord-000079-533xlisc	61	6	ssc	ssc	NOUN
cord-000079-533xlisc	61	7	versus	versus	ADP
cord-000079-533xlisc	61	8	fl1	fl1	ADV
cord-000079-533xlisc	61	9	(	(	PUNCT
cord-000079-533xlisc	61	10	in	in	ADP
cord-000079-533xlisc	61	11	logarithmic	logarithmic	ADJ
cord-000079-533xlisc	61	12	mode	mode	NOUN
cord-000079-533xlisc	61	13	)	)	PUNCT
cord-000079-533xlisc	61	14	dot	dot	NOUN
cord-000079-533xlisc	61	15	plot	plot	NOUN
cord-000079-533xlisc	61	16	after	after	ADP
cord-000079-533xlisc	61	17	exclusion	exclusion	NOUN
cord-000079-533xlisc	61	18	of	of	ADP
cord-000079-533xlisc	61	19	dead	dead	ADJ
cord-000079-533xlisc	61	20	cells	cell	NOUN
cord-000079-533xlisc	61	21	and	and	CCONJ
cord-000079-533xlisc	61	22	debris	debris	NOUN
cord-000079-533xlisc	61	23	as	as	SCONJ
cord-000079-533xlisc	61	24	described	describe	VERB
cord-000079-533xlisc	61	25	above	above	ADP
cord-000079-533xlisc	61	26	.	.	PUNCT
cord-000079-533xlisc	62	1	for	for	ADP
cord-000079-533xlisc	62	2	analysis	analysis	NOUN
cord-000079-533xlisc	62	3	of	of	ADP
cord-000079-533xlisc	62	4	cd133	cd133	ADJ
cord-000079-533xlisc	62	5	expression	expression	NOUN
cord-000079-533xlisc	62	6	cells	cell	NOUN
cord-000079-533xlisc	62	7	were	be	AUX
cord-000079-533xlisc	62	8	stained	stain	VERB
cord-000079-533xlisc	62	9	with	with	ADP
cord-000079-533xlisc	62	10	allophycocyanin	allophycocyanin	ADJ
cord-000079-533xlisc	62	11	(	(	PUNCT
cord-000079-533xlisc	62	12	apc	apc	PROPN
cord-000079-533xlisc	62	13	)	)	PUNCT
cord-000079-533xlisc	62	14	conjugated	conjugate	VERB
cord-000079-533xlisc	62	15	monoclonal	monoclonal	NOUN
cord-000079-533xlisc	62	16	cd133/1	cd133/1	PUNCT
cord-000079-533xlisc	62	17	(	(	PUNCT
cord-000079-533xlisc	62	18	ac133	ac133	PROPN
cord-000079-533xlisc	62	19	)	)	PUNCT
cord-000079-533xlisc	62	20	antibodies	antibody	NOUN
cord-000079-533xlisc	62	21	(	(	PUNCT
cord-000079-533xlisc	62	22	miltenyi	miltenyi	PROPN
cord-000079-533xlisc	62	23	,	,	PUNCT
cord-000079-533xlisc	62	24	bergisch	bergisch	PROPN
cord-000079-533xlisc	62	25	-	-	PUNCT
cord-000079-533xlisc	62	26	gladbach	gladbach	PROPN
cord-000079-533xlisc	62	27	,	,	PUNCT
cord-000079-533xlisc	62	28	germany	germany	PROPN
cord-000079-533xlisc	62	29	)	)	PUNCT
cord-000079-533xlisc	62	30	,	,	PUNCT
cord-000079-533xlisc	62	31	according	accord	VERB
cord-000079-533xlisc	62	32	to	to	ADP
cord-000079-533xlisc	62	33	the	the	DET
cord-000079-533xlisc	62	34	manufacturer	manufacturer	NOUN
cord-000079-533xlisc	62	35	's	's	PART
cord-000079-533xlisc	62	36	general	general	ADJ
cord-000079-533xlisc	62	37	protocol	protocol	NOUN
cord-000079-533xlisc	62	38	for	for	ADP
cord-000079-533xlisc	62	39	immunofluorescent	immunofluorescent	NOUN
cord-000079-533xlisc	62	40	staining	stain	VERB
cord-000079-533xlisc	62	41	(	(	PUNCT
cord-000079-533xlisc	62	42	for	for	ADP
cord-000079-533xlisc	62	43	10	10	NUM
cord-000079-533xlisc	62	44	min	min	NOUN
cord-000079-533xlisc	62	45	in	in	ADP
cord-000079-533xlisc	62	46	the	the	DET
cord-000079-533xlisc	62	47	dark	dark	NOUN
cord-000079-533xlisc	62	48	at	at	ADP
cord-000079-533xlisc	62	49	4uc	4uc	NOUN
cord-000079-533xlisc	62	50	)	)	PUNCT
cord-000079-533xlisc	62	51	.	.	PUNCT
cord-000079-533xlisc	63	1	cd133	cd133	PROPN
cord-000079-533xlisc	63	2	-	-	PUNCT
cord-000079-533xlisc	63	3	apc	apc	PROPN
cord-000079-533xlisc	63	4	was	be	AUX
cord-000079-533xlisc	63	5	excited	excite	VERB
cord-000079-533xlisc	63	6	at	at	ADP
cord-000079-533xlisc	63	7	635	635	NUM
cord-000079-533xlisc	63	8	nm	nm	PROPN
cord-000079-533xlisc	63	9	,	,	PUNCT
cord-000079-533xlisc	63	10	the	the	DET
cord-000079-533xlisc	63	11	fluorescence	fluorescence	NOUN
cord-000079-533xlisc	63	12	was	be	AUX
cord-000079-533xlisc	63	13	measured	measure	VERB
cord-000079-533xlisc	63	14	through	through	ADP
cord-000079-533xlisc	63	15	670/	670/	NUM
cord-000079-533xlisc	63	16	30	30	NUM
cord-000079-533xlisc	63	17	bp	bp	PROPN
cord-000079-533xlisc	63	18	optical	optical	ADJ
cord-000079-533xlisc	63	19	filter	filter	NOUN
cord-000079-533xlisc	63	20	,	,	PUNCT
cord-000079-533xlisc	63	21	and	and	CCONJ
cord-000079-533xlisc	63	22	alive	alive	ADJ
cord-000079-533xlisc	63	23	cd133	cd133	PROPN
cord-000079-533xlisc	63	24	+	+	SYM
cord-000079-533xlisc	63	25	cells	cell	NOUN
cord-000079-533xlisc	63	26	were	be	AUX
cord-000079-533xlisc	63	27	defined	define	VERB
cord-000079-533xlisc	63	28	on	on	ADP
cord-000079-533xlisc	63	29	ssc	ssc	NOUN
cord-000079-533xlisc	63	30	versus	versus	ADP
cord-000079-533xlisc	63	31	fl6	fl6	PROPN
cord-000079-533xlisc	63	32	(	(	PUNCT
cord-000079-533xlisc	63	33	in	in	ADP
cord-000079-533xlisc	63	34	logarithmic	logarithmic	ADJ
cord-000079-533xlisc	63	35	mode	mode	NOUN
cord-000079-533xlisc	63	36	)	)	PUNCT
cord-000079-533xlisc	63	37	dot	dot	NOUN
cord-000079-533xlisc	63	38	plot	plot	NOUN
cord-000079-533xlisc	63	39	.	.	PUNCT
cord-000079-533xlisc	64	1	non	non	ADJ
cord-000079-533xlisc	64	2	-	-	ADJ
cord-000079-533xlisc	64	3	stained	stained	ADJ
cord-000079-533xlisc	64	4	cell	cell	NOUN
cord-000079-533xlisc	64	5	suspension	suspension	NOUN
cord-000079-533xlisc	64	6	was	be	AUX
cord-000079-533xlisc	64	7	used	use	VERB
cord-000079-533xlisc	64	8	as	as	ADP
cord-000079-533xlisc	64	9	a	a	DET
cord-000079-533xlisc	64	10	control	control	NOUN
cord-000079-533xlisc	64	11	.	.	PUNCT
cord-000079-533xlisc	65	1	gfp+	gfp+	PROPN
cord-000079-533xlisc	65	2	tumor	tumor	NOUN
cord-000079-533xlisc	65	3	cells	cell	NOUN
cord-000079-533xlisc	65	4	were	be	AUX
cord-000079-533xlisc	65	5	sorted	sort	VERB
cord-000079-533xlisc	65	6	in	in	ADP
cord-000079-533xlisc	65	7	''	''	PUNCT
cord-000079-533xlisc	65	8	purify	purify	VERB
cord-000079-533xlisc	65	9	1	1	NUM
cord-000079-533xlisc	65	10	''	''	PUNCT
cord-000079-533xlisc	65	11	mode	mode	NOUN
cord-000079-533xlisc	65	12	into	into	ADP
cord-000079-533xlisc	65	13	polypropylene	polypropylene	PROPN
cord-000079-533xlisc	65	14	round	round	ADJ
cord-000079-533xlisc	65	15	-	-	PUNCT
cord-000079-533xlisc	65	16	bottom	bottom	NOUN
cord-000079-533xlisc	65	17	falcon	falcon	NOUN
cord-000079-533xlisc	65	18	tubes	tube	NOUN
cord-000079-533xlisc	65	19	(	(	PUNCT
cord-000079-533xlisc	65	20	becton	becton	PROPN
cord-000079-533xlisc	65	21	dickinson	dickinson	PROPN
cord-000079-533xlisc	65	22	labware	labware	PROPN
cord-000079-533xlisc	65	23	europe	europe	PROPN
cord-000079-533xlisc	65	24	,	,	PUNCT
cord-000079-533xlisc	65	25	france	france	PROPN
cord-000079-533xlisc	65	26	)	)	PUNCT
cord-000079-533xlisc	65	27	containing	contain	VERB
cord-000079-533xlisc	65	28	culture	culture	NOUN
cord-000079-533xlisc	65	29	media	medium	NOUN
cord-000079-533xlisc	65	30	,	,	PUNCT
cord-000079-533xlisc	65	31	that	that	PRON
cord-000079-533xlisc	65	32	were	be	AUX
cord-000079-533xlisc	65	33	placed	place	VERB
cord-000079-533xlisc	65	34	on	on	ADP
cord-000079-533xlisc	65	35	ice	ice	NOUN
cord-000079-533xlisc	65	36	.	.	PUNCT
cord-000079-533xlisc	66	1	aliquots	aliquot	NOUN
cord-000079-533xlisc	66	2	from	from	ADP
cord-000079-533xlisc	66	3	some	some	DET
cord-000079-533xlisc	66	4	samples	sample	NOUN
cord-000079-533xlisc	66	5	at	at	ADP
cord-000079-533xlisc	66	6	the	the	DET
cord-000079-533xlisc	66	7	end	end	NOUN
cord-000079-533xlisc	66	8	of	of	ADP
cord-000079-533xlisc	66	9	the	the	DET
cord-000079-533xlisc	66	10	sorting	sort	VERB
cord-000079-533xlisc	66	11	were	be	AUX
cord-000079-533xlisc	66	12	removed	remove	VERB
cord-000079-533xlisc	66	13	and	and	CCONJ
cord-000079-533xlisc	66	14	reanalyzed	reanalyze	VERB
cord-000079-533xlisc	66	15	for	for	ADP
cord-000079-533xlisc	66	16	control	control	NOUN
cord-000079-533xlisc	66	17	of	of	ADP
cord-000079-533xlisc	66	18	the	the	DET
cord-000079-533xlisc	66	19	sort	sort	NOUN
cord-000079-533xlisc	66	20	purity	purity	NOUN
cord-000079-533xlisc	66	21	that	that	PRON
cord-000079-533xlisc	66	22	was	be	AUX
cord-000079-533xlisc	66	23	greater	great	ADJ
cord-000079-533xlisc	66	24	than	than	ADP
cord-000079-533xlisc	66	25	98	98	NUM
cord-000079-533xlisc	66	26	%	%	NOUN
cord-000079-533xlisc	66	27	.	.	PUNCT
cord-000079-533xlisc	67	1	sorted	sorted	ADJ
cord-000079-533xlisc	67	2	cells	cell	NOUN
cord-000079-533xlisc	67	3	were	be	AUX
cord-000079-533xlisc	67	4	either	either	CCONJ
cord-000079-533xlisc	67	5	cultured	cultured	ADJ
cord-000079-533xlisc	67	6	in	in	ADP
cord-000079-533xlisc	67	7	neurobasal	neurobasal	PROPN
cord-000079-533xlisc	67	8	medium	medium	NOUN
cord-000079-533xlisc	67	9	(	(	PUNCT
cord-000079-533xlisc	67	10	invitrogen	invitrogen	PROPN
cord-000079-533xlisc	67	11	,	,	PUNCT
cord-000079-533xlisc	67	12	carlsbad	carlsbad	PROPN
cord-000079-533xlisc	67	13	,	,	PUNCT
cord-000079-533xlisc	67	14	ca	can	AUX
cord-000079-533xlisc	67	15	)	)	PUNCT
cord-000079-533xlisc	67	16	with	with	ADP
cord-000079-533xlisc	67	17	b27	b27	PROPN
cord-000079-533xlisc	67	18	supplement	supplement	NOUN
cord-000079-533xlisc	67	19	(	(	PUNCT
cord-000079-533xlisc	67	20	20	20	NUM
cord-000079-533xlisc	67	21	ml	ml	NUM
cord-000079-533xlisc	67	22	/	/	SYM
cord-000079-533xlisc	67	23	ml	ml	PROPN
cord-000079-533xlisc	67	24	;	;	PUNCT
cord-000079-533xlisc	67	25	invitrogen	invitrogen	PROPN
cord-000079-533xlisc	67	26	)	)	PUNCT
cord-000079-533xlisc	67	27	,	,	PUNCT
cord-000079-533xlisc	67	28	glutamax	glutamax	NOUN
cord-000079-533xlisc	67	29	(	(	PUNCT
cord-000079-533xlisc	67	30	10	10	NUM
cord-000079-533xlisc	67	31	ml	ml	NUM
cord-000079-533xlisc	67	32	/	/	SYM
cord-000079-533xlisc	67	33	ml	ml	PROPN
cord-000079-533xlisc	67	34	;	;	PUNCT
cord-000079-533xlisc	67	35	invitrogen	invitrogen	PROPN
cord-000079-533xlisc	67	36	)	)	PUNCT
cord-000079-533xlisc	67	37	,	,	PUNCT
cord-000079-533xlisc	67	38	fibroblast	fibroblast	ADJ
cord-000079-533xlisc	67	39	growth	growth	NOUN
cord-000079-533xlisc	67	40	factor	factor	NOUN
cord-000079-533xlisc	67	41	2	2	NUM
cord-000079-533xlisc	67	42	(	(	PUNCT
cord-000079-533xlisc	67	43	20	20	NUM
cord-000079-533xlisc	67	44	ng	ng	PROPN
cord-000079-533xlisc	67	45	/	/	SYM
cord-000079-533xlisc	67	46	ml	ml	PROPN
cord-000079-533xlisc	67	47	;	;	PUNCT
cord-000079-533xlisc	67	48	peprotech	peprotech	NOUN
cord-000079-533xlisc	67	49	,	,	PUNCT
cord-000079-533xlisc	67	50	rocky	rocky	PROPN
cord-000079-533xlisc	67	51	hill	hill	PROPN
cord-000079-533xlisc	67	52	,	,	PUNCT
cord-000079-533xlisc	67	53	nj	nj	PROPN
cord-000079-533xlisc	67	54	)	)	PUNCT
cord-000079-533xlisc	67	55	,	,	PUNCT
cord-000079-533xlisc	67	56	epidermal	epidermal	ADJ
cord-000079-533xlisc	67	57	growth	growth	NOUN
cord-000079-533xlisc	67	58	factor	factor	NOUN
cord-000079-533xlisc	67	59	(	(	PUNCT
cord-000079-533xlisc	67	60	20	20	NUM
cord-000079-533xlisc	67	61	ng	ng	PROPN
cord-000079-533xlisc	67	62	ml	ml	PROPN
cord-000079-533xlisc	67	63	;	;	PUNCT
cord-000079-533xlisc	67	64	peprotech	peprotech	NOUN
cord-000079-533xlisc	67	65	)	)	PUNCT
cord-000079-533xlisc	67	66	or	or	CCONJ
cord-000079-533xlisc	67	67	transferred	transfer	VERB
cord-000079-533xlisc	67	68	to	to	ADP
cord-000079-533xlisc	67	69	dmem	dmem	PROPN
cord-000079-533xlisc	67	70	supplemented	supplement	VERB
cord-000079-533xlisc	67	71	with	with	ADP
cord-000079-533xlisc	67	72	10	10	NUM
cord-000079-533xlisc	67	73	%	%	NOUN
cord-000079-533xlisc	67	74	fetal	fetal	ADJ
cord-000079-533xlisc	67	75	calf	calf	NOUN
cord-000079-533xlisc	67	76	serum	serum	NOUN
cord-000079-533xlisc	67	77	(	(	PUNCT
cord-000079-533xlisc	67	78	fcs	fc	NOUN
cord-000079-533xlisc	67	79	)	)	PUNCT
cord-000079-533xlisc	67	80	and	and	CCONJ
cord-000079-533xlisc	67	81	1	1	NUM
cord-000079-533xlisc	67	82	%	%	NOUN
cord-000079-533xlisc	67	83	glutamine	glutamine	NOUN
cord-000079-533xlisc	67	84	and	and	CCONJ
cord-000079-533xlisc	67	85	grown	grow	VERB
cord-000079-533xlisc	67	86	on	on	ADP
cord-000079-533xlisc	67	87	cover	cover	NOUN
cord-000079-533xlisc	67	88	slips	slip	NOUN
cord-000079-533xlisc	67	89	in	in	ADP
cord-000079-533xlisc	67	90	24	24	NUM
cord-000079-533xlisc	67	91	well	well	ADJ
cord-000079-533xlisc	67	92	plates	plate	NOUN
cord-000079-533xlisc	67	93	.	.	PUNCT
cord-000079-533xlisc	68	1	immunofluorescence	immunofluorescence	NOUN
cord-000079-533xlisc	68	2	staining	staining	NOUN
cord-000079-533xlisc	68	3	of	of	ADP
cord-000079-533xlisc	68	4	spheroids	spheroid	NOUN
cord-000079-533xlisc	68	5	/	/	SYM
cord-000079-533xlisc	68	6	adherent	adherent	NOUN
cord-000079-533xlisc	68	7	cells	cell	NOUN
cord-000079-533xlisc	68	8	spheroids	spheroid	NOUN
cord-000079-533xlisc	68	9	/	/	SYM
cord-000079-533xlisc	68	10	adherent	adherent	NOUN
cord-000079-533xlisc	68	11	cells	cell	NOUN
cord-000079-533xlisc	68	12	were	be	AUX
cord-000079-533xlisc	68	13	stained	stain	VERB
cord-000079-533xlisc	68	14	with	with	ADP
cord-000079-533xlisc	68	15	human	human	ADJ
cord-000079-533xlisc	68	16	-	-	PUNCT
cord-000079-533xlisc	68	17	specific	specific	ADJ
cord-000079-533xlisc	68	18	mouse	mouse	NOUN
cord-000079-533xlisc	68	19	-	-	PUNCT
cord-000079-533xlisc	68	20	anti	anti	ADJ
cord-000079-533xlisc	68	21	-	-	ADJ
cord-000079-533xlisc	68	22	nestin	nestin	ADJ
cord-000079-533xlisc	68	23	antibodies	antibody	NOUN
cord-000079-533xlisc	68	24	(	(	PUNCT
cord-000079-533xlisc	68	25	millipore	millipore	PROPN
cord-000079-533xlisc	68	26	,	,	PUNCT
cord-000079-533xlisc	68	27	billerica	billerica	PROPN
cord-000079-533xlisc	68	28	,	,	PUNCT
cord-000079-533xlisc	68	29	ma	ma	PROPN
cord-000079-533xlisc	68	30	)	)	PUNCT
cord-000079-533xlisc	68	31	,	,	PUNCT
cord-000079-533xlisc	68	32	goat	goat	PROPN
cord-000079-533xlisc	68	33	-	-	PUNCT
cord-000079-533xlisc	68	34	anti	anti	ADJ
cord-000079-533xlisc	68	35	-	-	ADJ
cord-000079-533xlisc	68	36	sox2	sox2	ADJ
cord-000079-533xlisc	68	37	antibodies	antibody	NOUN
cord-000079-533xlisc	68	38	(	(	PUNCT
cord-000079-533xlisc	68	39	r&d	r&d	NOUN
cord-000079-533xlisc	68	40	)	)	PUNCT
cord-000079-533xlisc	68	41	,	,	PUNCT
cord-000079-533xlisc	68	42	mouse	mouse	NOUN
cord-000079-533xlisc	68	43	-	-	PUNCT
cord-000079-533xlisc	68	44	anti	anti	ADJ
cord-000079-533xlisc	68	45	-	-	ADJ
cord-000079-533xlisc	68	46	b2tubuliniii	b2tubuliniii	ADJ
cord-000079-533xlisc	68	47	(	(	PUNCT
cord-000079-533xlisc	68	48	millipore	millipore	PROPN
cord-000079-533xlisc	68	49	)	)	PUNCT
cord-000079-533xlisc	68	50	antibodies	antibody	NOUN
cord-000079-533xlisc	68	51	and	and	CCONJ
cord-000079-533xlisc	68	52	mouse	mouse	NOUN
cord-000079-533xlisc	68	53	-	-	PUNCT
cord-000079-533xlisc	68	54	anti	anti	ADJ
cord-000079-533xlisc	68	55	-	-	ADJ
cord-000079-533xlisc	68	56	gfap	gfap	ADJ
cord-000079-533xlisc	68	57	antibodies	antibody	NOUN
cord-000079-533xlisc	68	58	(	(	PUNCT
cord-000079-533xlisc	68	59	millipore	millipore	PROPN
cord-000079-533xlisc	68	60	)	)	PUNCT
cord-000079-533xlisc	68	61	.	.	PUNCT
cord-000079-533xlisc	69	1	primary	primary	ADJ
cord-000079-533xlisc	69	2	antibodies	antibody	NOUN
cord-000079-533xlisc	69	3	were	be	AUX
cord-000079-533xlisc	69	4	incubated	incubate	VERB
cord-000079-533xlisc	69	5	overnight	overnight	ADV
cord-000079-533xlisc	69	6	at	at	ADP
cord-000079-533xlisc	69	7	4uc	4uc	NOUN
cord-000079-533xlisc	69	8	.	.	PUNCT
cord-000079-533xlisc	70	1	alexa	alexa	NOUN
cord-000079-533xlisc	70	2	-	-	PUNCT
cord-000079-533xlisc	70	3	fluor647	fluor647	NOUN
cord-000079-533xlisc	70	4	-	-	ADJ
cord-000079-533xlisc	70	5	goatanti	goatanti	ADJ
cord-000079-533xlisc	70	6	-	-	PUNCT
cord-000079-533xlisc	70	7	mouse	mouse	NOUN
cord-000079-533xlisc	70	8	und	und	ADJ
cord-000079-533xlisc	70	9	alexa	alexa	ADJ
cord-000079-533xlisc	70	10	-	-	PUNCT
cord-000079-533xlisc	70	11	fluor647	fluor647	NOUN
cord-000079-533xlisc	70	12	-	-	PUNCT
cord-000079-533xlisc	70	13	donkey	donkey	NOUN
cord-000079-533xlisc	70	14	-	-	PUNCT
cord-000079-533xlisc	70	15	anti	anti	ADJ
cord-000079-533xlisc	70	16	-	-	ADJ
cord-000079-533xlisc	70	17	goat	goat	ADJ
cord-000079-533xlisc	70	18	antibodies	antibodies	PROPN
cord-000079-533xlisc	70	19	(	(	PUNCT
cord-000079-533xlisc	70	20	dianova	dianova	PROPN
cord-000079-533xlisc	70	21	,	,	PUNCT
cord-000079-533xlisc	70	22	hamburg	hamburg	PROPN
cord-000079-533xlisc	70	23	,	,	PUNCT
cord-000079-533xlisc	70	24	germany	germany	PROPN
cord-000079-533xlisc	70	25	)	)	PUNCT
cord-000079-533xlisc	70	26	were	be	AUX
cord-000079-533xlisc	70	27	used	use	VERB
cord-000079-533xlisc	70	28	as	as	ADP
cord-000079-533xlisc	70	29	secondary	secondary	ADJ
cord-000079-533xlisc	70	30	antibodies	antibody	NOUN
cord-000079-533xlisc	70	31	over	over	ADP
cord-000079-533xlisc	70	32	night	night	NOUN
cord-000079-533xlisc	70	33	at	at	ADP
cord-000079-533xlisc	70	34	4uc	4uc	PROPN
cord-000079-533xlisc	70	35	(	(	PUNCT
cord-000079-533xlisc	70	36	for	for	ADP
cord-000079-533xlisc	70	37	spheroids	spheroid	NOUN
cord-000079-533xlisc	70	38	)	)	PUNCT
cord-000079-533xlisc	70	39	or	or	CCONJ
cord-000079-533xlisc	70	40	for	for	ADP
cord-000079-533xlisc	70	41	2h	2h	NUM
cord-000079-533xlisc	70	42	at	at	ADP
cord-000079-533xlisc	70	43	room	room	NOUN
cord-000079-533xlisc	70	44	temperature	temperature	NOUN
cord-000079-533xlisc	70	45	(	(	PUNCT
cord-000079-533xlisc	70	46	for	for	ADP
cord-000079-533xlisc	70	47	adherent	adherent	NOUN
cord-000079-533xlisc	70	48	cells	cell	NOUN
cord-000079-533xlisc	70	49	)	)	PUNCT
cord-000079-533xlisc	70	50	.	.	PUNCT
cord-000079-533xlisc	71	1	spheroids	spheroid	NOUN
cord-000079-533xlisc	71	2	were	be	AUX
cord-000079-533xlisc	71	3	examined	examine	VERB
cord-000079-533xlisc	71	4	under	under	ADP
cord-000079-533xlisc	71	5	a	a	DET
cord-000079-533xlisc	71	6	fluorescence	fluorescence	ADJ
cord-000079-533xlisc	71	7	microscope	microscope	NOUN
cord-000079-533xlisc	71	8	(	(	PUNCT
cord-000079-533xlisc	71	9	nikon	nikon	PROPN
cord-000079-533xlisc	71	10	,	,	PUNCT
cord-000079-533xlisc	71	11	tokyo	tokyo	PROPN
cord-000079-533xlisc	71	12	,	,	PUNCT
cord-000079-533xlisc	71	13	japan	japan	PROPN
cord-000079-533xlisc	71	14	)	)	PUNCT
cord-000079-533xlisc	71	15	and	and	CCONJ
cord-000079-533xlisc	71	16	adherent	adherent	NOUN
cord-000079-533xlisc	71	17	cells	cell	NOUN
cord-000079-533xlisc	71	18	were	be	AUX
cord-000079-533xlisc	71	19	analyzed	analyze	VERB
cord-000079-533xlisc	71	20	by	by	ADP
cord-000079-533xlisc	71	21	confocal	confocal	ADJ
cord-000079-533xlisc	71	22	scanning	scan	VERB
cord-000079-533xlisc	71	23	laser	laser	NOUN
cord-000079-533xlisc	71	24	microscopy	microscopy	NOUN
cord-000079-533xlisc	71	25	(	(	PUNCT
cord-000079-533xlisc	71	26	zeiss	zeiss	X
cord-000079-533xlisc	71	27	,	,	PUNCT
cord-000079-533xlisc	71	28	jena	jena	PROPN
cord-000079-533xlisc	71	29	,	,	PUNCT
cord-000079-533xlisc	71	30	germany	germany	PROPN
cord-000079-533xlisc	71	31	)	)	PUNCT
cord-000079-533xlisc	71	32	.	.	PUNCT
cord-000079-533xlisc	72	1	the	the	DET
cord-000079-533xlisc	72	2	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	72	3	vector	vector	NOUN
cord-000079-533xlisc	72	4	plasmid	plasmid	NOUN
cord-000079-533xlisc	72	5	prrl.sincmvegfppre	prrl.sincmvegfppre	NOUN
cord-000079-533xlisc	72	6	was	be	AUX
cord-000079-533xlisc	72	7	published	publish	VERB
cord-000079-533xlisc	72	8	by	by	ADP
cord-000079-533xlisc	72	9	naldini	naldini	PROPN
cord-000079-533xlisc	72	10	et	et	X
cord-000079-533xlisc	72	11	al	al	PROPN
cord-000079-533xlisc	72	12	.	.	PUNCT
cord-000079-533xlisc	73	1	[	[	X
cord-000079-533xlisc	73	2	21	21	NUM
cord-000079-533xlisc	73	3	]	]	PUNCT
cord-000079-533xlisc	73	4	.	.	PUNCT
cord-000079-533xlisc	74	1	the	the	DET
cord-000079-533xlisc	74	2	construction	construction	NOUN
cord-000079-533xlisc	74	3	of	of	ADP
cord-000079-533xlisc	74	4	the	the	DET
cord-000079-533xlisc	74	5	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	74	6	vector	vector	NOUN
cord-000079-533xlisc	74	7	prrl.sincmv	prrl.sincmv	PROPN
cord-000079-533xlisc	74	8	-	-	PUNCT
cord-000079-533xlisc	74	9	tk	tk	PROPN
cord-000079-533xlisc	74	10	/	/	PROPN
cord-000079-533xlisc	74	11	egfppre	egfppre	PROPN
cord-000079-533xlisc	74	12	has	have	AUX
cord-000079-533xlisc	74	13	been	be	AUX
cord-000079-533xlisc	74	14	described	describe	VERB
cord-000079-533xlisc	74	15	previously	previously	ADV
cord-000079-533xlisc	74	16	.	.	PUNCT
cord-000079-533xlisc	75	1	the	the	DET
cord-000079-533xlisc	75	2	retroviral	retroviral	ADJ
cord-000079-533xlisc	75	3	vector	vector	NOUN
cord-000079-533xlisc	75	4	pmp71	pmp71	NOUN
cord-000079-533xlisc	75	5	-	-	PUNCT
cord-000079-533xlisc	75	6	egfp	egfp	NOUN
cord-000079-533xlisc	75	7	-	-	PUNCT
cord-000079-533xlisc	75	8	pre	pre	NOUN
cord-000079-533xlisc	75	9	has	have	AUX
cord-000079-533xlisc	75	10	been	be	AUX
cord-000079-533xlisc	75	11	described	describe	VERB
cord-000079-533xlisc	75	12	previously	previously	ADV
cord-000079-533xlisc	75	13	[	[	X
cord-000079-533xlisc	75	14	22	22	NUM
cord-000079-533xlisc	75	15	]	]	PUNCT
cord-000079-533xlisc	75	16	.	.	PUNCT
cord-000079-533xlisc	76	1	the	the	DET
cord-000079-533xlisc	76	2	293	293	NUM
cord-000079-533xlisc	76	3	t	t	NOUN
cord-000079-533xlisc	76	4	cell	cell	NOUN
cord-000079-533xlisc	76	5	line	line	NOUN
cord-000079-533xlisc	76	6	was	be	AUX
cord-000079-533xlisc	76	7	used	use	VERB
cord-000079-533xlisc	76	8	for	for	ADP
cord-000079-533xlisc	76	9	transient	transient	ADJ
cord-000079-533xlisc	76	10	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	76	11	vector	vector	NOUN
cord-000079-533xlisc	76	12	production	production	NOUN
cord-000079-533xlisc	76	13	.	.	PUNCT
cord-000079-533xlisc	77	1	the	the	PRON
cord-000079-533xlisc	77	2	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	77	3	vector	vector	NOUN
cord-000079-533xlisc	77	4	plasmid	plasmid	ADJ
cord-000079-533xlisc	77	5	prrl.sincmv	prrl.sincmv	NOUN
cord-000079-533xlisc	77	6	-	-	PUNCT
cord-000079-533xlisc	77	7	tk/	tk/	NOUN
cord-000079-533xlisc	77	8	egfppre	egfppre	NOUN
cord-000079-533xlisc	77	9	(	(	PUNCT
cord-000079-533xlisc	77	10	5	5	NUM
cord-000079-533xlisc	77	11	mg	mg	NOUN
cord-000079-533xlisc	77	12	)	)	PUNCT
cord-000079-533xlisc	77	13	or	or	CCONJ
cord-000079-533xlisc	77	14	prrl.sincmvegfppre	prrl.sincmvegfppre	NUM
cord-000079-533xlisc	77	15	(	(	PUNCT
cord-000079-533xlisc	77	16	5	5	NUM
cord-000079-533xlisc	77	17	mg	mg	NOUN
cord-000079-533xlisc	77	18	)	)	PUNCT
cord-000079-533xlisc	77	19	,	,	PUNCT
cord-000079-533xlisc	77	20	the	the	DET
cord-000079-533xlisc	77	21	hiv	hiv	PROPN
cord-000079-533xlisc	77	22	gagpol	gagpol	PROPN
cord-000079-533xlisc	77	23	-	-	PUNCT
cord-000079-533xlisc	77	24	rev	rev	NOUN
cord-000079-533xlisc	77	25	expression	expression	NOUN
cord-000079-533xlisc	77	26	plasmid	plasmid	PROPN
cord-000079-533xlisc	77	27	pcmv	pcmv	VERB
cord-000079-533xlisc	77	28	-	-	PUNCT
cord-000079-533xlisc	77	29	dr8.91(12.5	dr8.91(12.5	NOUN
cord-000079-533xlisc	77	30	mg	mg	INTJ
cord-000079-533xlisc	77	31	)	)	PUNCT
cord-000079-533xlisc	78	1	[	[	X
cord-000079-533xlisc	78	2	21	21	NUM
cord-000079-533xlisc	78	3	]	]	PUNCT
cord-000079-533xlisc	78	4	and	and	CCONJ
cord-000079-533xlisc	78	5	2	2	NUM
cord-000079-533xlisc	78	6	mg	mg	NOUN
cord-000079-533xlisc	78	7	of	of	ADP
cord-000079-533xlisc	78	8	the	the	DET
cord-000079-533xlisc	78	9	envelope	envelope	NOUN
cord-000079-533xlisc	78	10	expression	expression	NOUN
cord-000079-533xlisc	78	11	plasmid	plasmid	PROPN
cord-000079-533xlisc	78	12	phcmv	phcmv	PROPN
cord-000079-533xlisc	78	13	-	-	PUNCT
cord-000079-533xlisc	78	14	lcmv	lcmv	PROPN
cord-000079-533xlisc	78	15	-	-	PUNCT
cord-000079-533xlisc	78	16	gp	gp	PROPN
cord-000079-533xlisc	78	17	[	[	PUNCT
cord-000079-533xlisc	78	18	14	14	NUM
cord-000079-533xlisc	78	19	]	]	PUNCT
cord-000079-533xlisc	78	20	or	or	CCONJ
cord-000079-533xlisc	78	21	pcmv	pcmv	VERB
cord-000079-533xlisc	78	22	-	-	PUNCT
cord-000079-533xlisc	78	23	g	g	NOUN
cord-000079-533xlisc	79	1	[	[	PUNCT
cord-000079-533xlisc	79	2	23	23	NUM
cord-000079-533xlisc	79	3	]	]	PUNCT
cord-000079-533xlisc	79	4	were	be	AUX
cord-000079-533xlisc	79	5	cotransfected	cotransfecte	VERB
cord-000079-533xlisc	79	6	into	into	ADP
cord-000079-533xlisc	79	7	293	293	NUM
cord-000079-533xlisc	79	8	t	t	PROPN
cord-000079-533xlisc	79	9	cells	cell	NOUN
cord-000079-533xlisc	79	10	and	and	CCONJ
cord-000079-533xlisc	79	11	concentrated	concentrate	VERB
cord-000079-533xlisc	79	12	as	as	SCONJ
cord-000079-533xlisc	79	13	described	describe	VERB
cord-000079-533xlisc	79	14	previously	previously	ADV
cord-000079-533xlisc	79	15	[	[	X
cord-000079-533xlisc	79	16	18	18	NUM
cord-000079-533xlisc	79	17	]	]	PUNCT
cord-000079-533xlisc	79	18	.	.	PUNCT
cord-000079-533xlisc	80	1	for	for	ADP
cord-000079-533xlisc	80	2	the	the	DET
cord-000079-533xlisc	80	3	production	production	NOUN
cord-000079-533xlisc	80	4	of	of	ADP
cord-000079-533xlisc	80	5	retroviral	retroviral	ADJ
cord-000079-533xlisc	80	6	vectors	vector	NOUN
cord-000079-533xlisc	80	7	,	,	PUNCT
cord-000079-533xlisc	80	8	293	293	NUM
cord-000079-533xlisc	80	9	t	t	NOUN
cord-000079-533xlisc	80	10	cells	cell	NOUN
cord-000079-533xlisc	80	11	were	be	AUX
cord-000079-533xlisc	80	12	transfected	transfecte	VERB
cord-000079-533xlisc	80	13	with	with	ADP
cord-000079-533xlisc	80	14	7.5	7.5	NUM
cord-000079-533xlisc	80	15	mg	mg	NOUN
cord-000079-533xlisc	80	16	of	of	ADP
cord-000079-533xlisc	80	17	pmp71	pmp71	NOUN
cord-000079-533xlisc	80	18	-	-	PUNCT
cord-000079-533xlisc	80	19	egfp	egfp	NOUN
cord-000079-533xlisc	80	20	-	-	PUNCT
cord-000079-533xlisc	80	21	pre	pre	ADJ
cord-000079-533xlisc	80	22	,	,	PUNCT
cord-000079-533xlisc	80	23	12.5	12.5	NUM
cord-000079-533xlisc	80	24	mg	mg	NOUN
cord-000079-533xlisc	80	25	of	of	ADP
cord-000079-533xlisc	80	26	psv	psv	PROPN
cord-000079-533xlisc	80	27	-	-	PUNCT
cord-000079-533xlisc	80	28	mo	mo	PROPN
cord-000079-533xlisc	80	29	-	-	PUNCT
cord-000079-533xlisc	80	30	mlvgagpol	mlvgagpol	PROPN
cord-000079-533xlisc	80	31	,	,	PUNCT
cord-000079-533xlisc	80	32	and	and	CCONJ
cord-000079-533xlisc	80	33	2	2	NUM
cord-000079-533xlisc	80	34	mg	mg	NOUN
cord-000079-533xlisc	80	35	of	of	ADP
cord-000079-533xlisc	80	36	the	the	DET
cord-000079-533xlisc	80	37	envelope	envelope	NOUN
cord-000079-533xlisc	80	38	expression	expression	NOUN
cord-000079-533xlisc	80	39	plasmid	plasmid	PROPN
cord-000079-533xlisc	80	40	phcmv	phcmv	PROPN
cord-000079-533xlisc	80	41	-	-	PUNCT
cord-000079-533xlisc	80	42	lcmv	lcmv	PROPN
cord-000079-533xlisc	80	43	-	-	PUNCT
cord-000079-533xlisc	80	44	gp	gp	PROPN
cord-000079-533xlisc	81	1	[	[	PUNCT
cord-000079-533xlisc	81	2	14	14	NUM
cord-000079-533xlisc	81	3	]	]	PUNCT
cord-000079-533xlisc	81	4	or	or	CCONJ
cord-000079-533xlisc	81	5	pcmv	pcmv	VERB
cord-000079-533xlisc	81	6	-	-	PUNCT
cord-000079-533xlisc	81	7	g	g	NOUN
cord-000079-533xlisc	82	1	[	[	PUNCT
cord-000079-533xlisc	82	2	23	23	NUM
cord-000079-533xlisc	82	3	]	]	PUNCT
cord-000079-533xlisc	82	4	.	.	PUNCT
cord-000079-533xlisc	83	1	vectors	vector	NOUN
cord-000079-533xlisc	83	2	were	be	AUX
cord-000079-533xlisc	83	3	harvested	harvest	VERB
cord-000079-533xlisc	83	4	and	and	CCONJ
cord-000079-533xlisc	83	5	concentrated	concentrate	VERB
cord-000079-533xlisc	83	6	as	as	SCONJ
cord-000079-533xlisc	83	7	described	describe	VERB
cord-000079-533xlisc	83	8	previously	previously	ADV
cord-000079-533xlisc	83	9	[	[	X
cord-000079-533xlisc	83	10	24	24	NUM
cord-000079-533xlisc	83	11	]	]	PUNCT
cord-000079-533xlisc	83	12	.	.	PUNCT
cord-000079-533xlisc	84	1	vectors	vector	NOUN
cord-000079-533xlisc	84	2	were	be	AUX
cord-000079-533xlisc	84	3	titered	titere	VERB
cord-000079-533xlisc	84	4	on	on	ADP
cord-000079-533xlisc	84	5	te671	te671	PROPN
cord-000079-533xlisc	84	6	cells	cell	NOUN
cord-000079-533xlisc	84	7	as	as	SCONJ
cord-000079-533xlisc	84	8	described	describe	VERB
cord-000079-533xlisc	84	9	previously	previously	ADV
cord-000079-533xlisc	84	10	[	[	X
cord-000079-533xlisc	84	11	18	18	NUM
cord-000079-533xlisc	84	12	]	]	PUNCT
cord-000079-533xlisc	84	13	.	.	PUNCT
cord-000079-533xlisc	85	1	intracranial	intracranial	ADJ
cord-000079-533xlisc	85	2	implantation	implantation	NOUN
cord-000079-533xlisc	85	3	of	of	ADP
cord-000079-533xlisc	85	4	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	85	5	spheroids	spheroid	NOUN
cord-000079-533xlisc	85	6	was	be	AUX
cord-000079-533xlisc	85	7	done	do	VERB
cord-000079-533xlisc	85	8	as	as	SCONJ
cord-000079-533xlisc	85	9	described	describe	VERB
cord-000079-533xlisc	85	10	previously	previously	ADV
cord-000079-533xlisc	85	11	[	[	X
cord-000079-533xlisc	85	12	25	25	NUM
cord-000079-533xlisc	85	13	]	]	PUNCT
cord-000079-533xlisc	85	14	.	.	PUNCT
cord-000079-533xlisc	86	1	three	three	NUM
cord-000079-533xlisc	86	2	weeks	week	NOUN
cord-000079-533xlisc	86	3	to	to	ADP
cord-000079-533xlisc	86	4	one	one	NUM
cord-000079-533xlisc	86	5	month	month	NOUN
cord-000079-533xlisc	86	6	after	after	ADP
cord-000079-533xlisc	86	7	implantation	implantation	NOUN
cord-000079-533xlisc	86	8	,	,	PUNCT
cord-000079-533xlisc	86	9	the	the	DET
cord-000079-533xlisc	86	10	animals	animal	NOUN
cord-000079-533xlisc	86	11	were	be	AUX
cord-000079-533xlisc	86	12	anesthetized	anesthetize	VERB
cord-000079-533xlisc	86	13	and	and	CCONJ
cord-000079-533xlisc	86	14	prepared	prepare	VERB
cord-000079-533xlisc	86	15	for	for	ADP
cord-000079-533xlisc	86	16	vector	vector	NOUN
cord-000079-533xlisc	86	17	injection	injection	NOUN
cord-000079-533xlisc	86	18	.	.	PUNCT
cord-000079-533xlisc	87	1	the	the	DET
cord-000079-533xlisc	87	2	skin	skin	NOUN
cord-000079-533xlisc	87	3	was	be	AUX
cord-000079-533xlisc	87	4	withdrawn	withdraw	VERB
cord-000079-533xlisc	87	5	to	to	PART
cord-000079-533xlisc	87	6	reveal	reveal	VERB
cord-000079-533xlisc	87	7	the	the	DET
cord-000079-533xlisc	87	8	location	location	NOUN
cord-000079-533xlisc	87	9	of	of	ADP
cord-000079-533xlisc	87	10	the	the	DET
cord-000079-533xlisc	87	11	craniotomy	craniotomy	NOUN
cord-000079-533xlisc	87	12	.	.	PUNCT
cord-000079-533xlisc	88	1	2	2	NUM
cord-000079-533xlisc	88	2	times	time	NOUN
cord-000079-533xlisc	88	3	10	10	NUM
cord-000079-533xlisc	88	4	ml	ml	NOUN
cord-000079-533xlisc	88	5	of	of	ADP
cord-000079-533xlisc	88	6	vector	vector	NOUN
cord-000079-533xlisc	88	7	stocks	stock	NOUN
cord-000079-533xlisc	88	8	were	be	AUX
cord-000079-533xlisc	88	9	delivered	deliver	VERB
cord-000079-533xlisc	88	10	into	into	ADP
cord-000079-533xlisc	88	11	the	the	DET
cord-000079-533xlisc	88	12	centre	centre	NOUN
cord-000079-533xlisc	88	13	of	of	ADP
cord-000079-533xlisc	88	14	the	the	DET
cord-000079-533xlisc	88	15	tumors	tumor	NOUN
cord-000079-533xlisc	88	16	using	use	VERB
cord-000079-533xlisc	88	17	a	a	DET
cord-000079-533xlisc	88	18	glass	glass	NOUN
cord-000079-533xlisc	88	19	syringe	syringe	NOUN
cord-000079-533xlisc	88	20	(	(	PUNCT
cord-000079-533xlisc	88	21	model	model	NOUN
cord-000079-533xlisc	88	22	701	701	NUM
cord-000079-533xlisc	88	23	,	,	PUNCT
cord-000079-533xlisc	88	24	hamilton	hamilton	PROPN
cord-000079-533xlisc	88	25	,	,	PUNCT
cord-000079-533xlisc	88	26	bonaduz	bonaduz	PROPN
cord-000079-533xlisc	88	27	,	,	PUNCT
cord-000079-533xlisc	88	28	switzerland	switzerland	PROPN
cord-000079-533xlisc	88	29	)	)	PUNCT
cord-000079-533xlisc	88	30	secured	secure	VERB
cord-000079-533xlisc	88	31	in	in	ADP
cord-000079-533xlisc	88	32	a	a	DET
cord-000079-533xlisc	88	33	microprocessor	microprocessor	NOUN
cord-000079-533xlisc	88	34	-	-	PUNCT
cord-000079-533xlisc	88	35	controlled	control	VERB
cord-000079-533xlisc	88	36	infusion	infusion	NOUN
cord-000079-533xlisc	88	37	pump	pump	NOUN
cord-000079-533xlisc	88	38	(	(	PUNCT
cord-000079-533xlisc	88	39	ump	ump	NOUN
cord-000079-533xlisc	88	40	2	2	NUM
cord-000079-533xlisc	88	41	-	-	SYM
cord-000079-533xlisc	88	42	1	1	NUM
cord-000079-533xlisc	88	43	,	,	PUNCT
cord-000079-533xlisc	88	44	world	world	NOUN
cord-000079-533xlisc	88	45	precision	precision	NOUN
cord-000079-533xlisc	88	46	instruments	instrument	NOUN
cord-000079-533xlisc	88	47	,	,	PUNCT
cord-000079-533xlisc	88	48	aston	aston	PROPN
cord-000079-533xlisc	88	49	,	,	PUNCT
cord-000079-533xlisc	88	50	stevenage	stevenage	PROPN
cord-000079-533xlisc	88	51	,	,	PUNCT
cord-000079-533xlisc	88	52	uk	uk	PROPN
cord-000079-533xlisc	88	53	)	)	PUNCT
cord-000079-533xlisc	88	54	.	.	PUNCT
cord-000079-533xlisc	89	1	the	the	DET
cord-000079-533xlisc	89	2	injection	injection	NOUN
cord-000079-533xlisc	89	3	coordinates	coordinate	NOUN
cord-000079-533xlisc	89	4	were	be	AUX
cord-000079-533xlisc	89	5	estimated	estimate	VERB
cord-000079-533xlisc	89	6	after	after	ADP
cord-000079-533xlisc	89	7	analyzing	analyze	VERB
cord-000079-533xlisc	89	8	mri	mri	NOUN
cord-000079-533xlisc	89	9	images	image	NOUN
cord-000079-533xlisc	89	10	for	for	ADP
cord-000079-533xlisc	89	11	each	each	DET
cord-000079-533xlisc	89	12	individual	individual	ADJ
cord-000079-533xlisc	89	13	lesion	lesion	NOUN
cord-000079-533xlisc	89	14	.	.	PUNCT
cord-000079-533xlisc	90	1	vector	vector	NOUN
cord-000079-533xlisc	90	2	infusion	infusion	NOUN
cord-000079-533xlisc	90	3	was	be	AUX
cord-000079-533xlisc	90	4	done	do	VERB
cord-000079-533xlisc	90	5	by	by	ADP
cord-000079-533xlisc	90	6	convection	convection	NOUN
cord-000079-533xlisc	90	7	enhanced	enhance	VERB
cord-000079-533xlisc	90	8	delivery	delivery	NOUN
cord-000079-533xlisc	90	9	in	in	ADP
cord-000079-533xlisc	90	10	the	the	DET
cord-000079-533xlisc	90	11	course	course	NOUN
cord-000079-533xlisc	90	12	of	of	ADP
cord-000079-533xlisc	90	13	25	25	NUM
cord-000079-533xlisc	90	14	min	min	NOUN
cord-000079-533xlisc	90	15	(	(	PUNCT
cord-000079-533xlisc	90	16	200	200	NUM
cord-000079-533xlisc	90	17	nl	nl	PROPN
cord-000079-533xlisc	90	18	/	/	SYM
cord-000079-533xlisc	90	19	min	min	NOUN
cord-000079-533xlisc	90	20	for	for	ADP
cord-000079-533xlisc	90	21	10	10	NUM
cord-000079-533xlisc	90	22	min	min	NOUN
cord-000079-533xlisc	90	23	,	,	PUNCT
cord-000079-533xlisc	90	24	followed	follow	VERB
cord-000079-533xlisc	90	25	by	by	ADP
cord-000079-533xlisc	90	26	400	400	NUM
cord-000079-533xlisc	90	27	nl	nl	NOUN
cord-000079-533xlisc	90	28	/	/	SYM
cord-000079-533xlisc	90	29	min	min	NOUN
cord-000079-533xlisc	90	30	for	for	ADP
cord-000079-533xlisc	90	31	10	10	NUM
cord-000079-533xlisc	90	32	min	min	NOUN
cord-000079-533xlisc	90	33	,	,	PUNCT
cord-000079-533xlisc	90	34	and	and	CCONJ
cord-000079-533xlisc	90	35	finally	finally	ADV
cord-000079-533xlisc	90	36	800	800	NUM
cord-000079-533xlisc	90	37	nl/	nl/	NOUN
cord-000079-533xlisc	90	38	min	min	NOUN
cord-000079-533xlisc	90	39	for	for	ADP
cord-000079-533xlisc	90	40	5	5	NUM
cord-000079-533xlisc	90	41	min	min	NOUN
cord-000079-533xlisc	90	42	)	)	PUNCT
cord-000079-533xlisc	90	43	.	.	PUNCT
cord-000079-533xlisc	91	1	after	after	ADP
cord-000079-533xlisc	91	2	infusion	infusion	NOUN
cord-000079-533xlisc	91	3	,	,	PUNCT
cord-000079-533xlisc	91	4	the	the	DET
cord-000079-533xlisc	91	5	needle	needle	NOUN
cord-000079-533xlisc	91	6	was	be	AUX
cord-000079-533xlisc	91	7	left	leave	VERB
cord-000079-533xlisc	91	8	in	in	ADP
cord-000079-533xlisc	91	9	place	place	NOUN
cord-000079-533xlisc	91	10	for	for	ADP
cord-000079-533xlisc	91	11	5	5	NUM
cord-000079-533xlisc	91	12	min	min	NOUN
cord-000079-533xlisc	91	13	to	to	PART
cord-000079-533xlisc	91	14	avoid	avoid	VERB
cord-000079-533xlisc	91	15	vector	vector	NOUN
cord-000079-533xlisc	91	16	reflux	reflux	NOUN
cord-000079-533xlisc	91	17	.	.	PUNCT
cord-000079-533xlisc	92	1	the	the	DET
cord-000079-533xlisc	92	2	needle	needle	NOUN
cord-000079-533xlisc	92	3	was	be	AUX
cord-000079-533xlisc	92	4	slowly	slowly	ADV
cord-000079-533xlisc	92	5	retracted	retract	VERB
cord-000079-533xlisc	92	6	and	and	CCONJ
cord-000079-533xlisc	92	7	the	the	DET
cord-000079-533xlisc	92	8	skinfolds	skinfold	NOUN
cord-000079-533xlisc	92	9	were	be	AUX
cord-000079-533xlisc	92	10	closed	close	VERB
cord-000079-533xlisc	92	11	with	with	ADP
cord-000079-533xlisc	92	12	polyamide	polyamide	NOUN
cord-000079-533xlisc	92	13	surgical	surgical	ADJ
cord-000079-533xlisc	92	14	thread	thread	NOUN
cord-000079-533xlisc	92	15	.	.	PUNCT
cord-000079-533xlisc	93	1	following	follow	VERB
cord-000079-533xlisc	93	2	surgery	surgery	NOUN
cord-000079-533xlisc	93	3	,	,	PUNCT
cord-000079-533xlisc	93	4	rats	rat	NOUN
cord-000079-533xlisc	93	5	were	be	AUX
cord-000079-533xlisc	93	6	allowed	allow	VERB
cord-000079-533xlisc	93	7	to	to	PART
cord-000079-533xlisc	93	8	recover	recover	VERB
cord-000079-533xlisc	93	9	in	in	ADP
cord-000079-533xlisc	93	10	an	an	DET
cord-000079-533xlisc	93	11	incubator	incubator	NOUN
cord-000079-533xlisc	93	12	set	set	VERB
cord-000079-533xlisc	93	13	at	at	ADP
cord-000079-533xlisc	93	14	35uc	35uc	PROPN
cord-000079-533xlisc	93	15	before	before	ADP
cord-000079-533xlisc	93	16	returning	return	VERB
cord-000079-533xlisc	93	17	them	they	PRON
cord-000079-533xlisc	93	18	to	to	ADP
cord-000079-533xlisc	93	19	the	the	DET
cord-000079-533xlisc	93	20	cages	cage	NOUN
cord-000079-533xlisc	93	21	.	.	PUNCT
cord-000079-533xlisc	94	1	rats	rat	NOUN
cord-000079-533xlisc	94	2	bearing	bear	VERB
cord-000079-533xlisc	94	3	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	94	4	xenografts	xenograft	NOUN
cord-000079-533xlisc	94	5	were	be	AUX
cord-000079-533xlisc	94	6	treated	treat	VERB
cord-000079-533xlisc	94	7	by	by	ADP
cord-000079-533xlisc	94	8	daily	daily	ADJ
cord-000079-533xlisc	94	9	i.p	i.p	PROPN
cord-000079-533xlisc	94	10	.	.	PUNCT
cord-000079-533xlisc	94	11	injections	injection	NOUN
cord-000079-533xlisc	94	12	of	of	ADP
cord-000079-533xlisc	94	13	50	50	NUM
cord-000079-533xlisc	94	14	mg	mg	NOUN
cord-000079-533xlisc	94	15	/	/	SYM
cord-000079-533xlisc	94	16	kg	kg	X
cord-000079-533xlisc	94	17	ganciclovir	ganciclovir	NOUN
cord-000079-533xlisc	94	18	(	(	PUNCT
cord-000079-533xlisc	94	19	gcv	gcv	PROPN
cord-000079-533xlisc	94	20	,	,	PUNCT
cord-000079-533xlisc	94	21	roche	roche	NOUN
cord-000079-533xlisc	94	22	,	,	PUNCT
cord-000079-533xlisc	94	23	basel	basel	NOUN
cord-000079-533xlisc	94	24	,	,	PUNCT
cord-000079-533xlisc	94	25	switzerland	switzerland	PROPN
cord-000079-533xlisc	94	26	)	)	PUNCT
cord-000079-533xlisc	94	27	.	.	PUNCT
cord-000079-533xlisc	95	1	animals	animal	NOUN
cord-000079-533xlisc	95	2	were	be	AUX
cord-000079-533xlisc	95	3	euthanized	euthanize	VERB
cord-000079-533xlisc	95	4	and	and	CCONJ
cord-000079-533xlisc	95	5	perfused	perfuse	VERB
cord-000079-533xlisc	95	6	with	with	ADP
cord-000079-533xlisc	95	7	sterile	sterile	ADJ
cord-000079-533xlisc	95	8	saline	saline	NOUN
cord-000079-533xlisc	95	9	and	and	CCONJ
cord-000079-533xlisc	95	10	thereafter	thereafter	ADV
cord-000079-533xlisc	95	11	with	with	ADP
cord-000079-533xlisc	95	12	4	4	NUM
cord-000079-533xlisc	95	13	%	%	NOUN
cord-000079-533xlisc	95	14	paraformaldehyde	paraformaldehyde	NOUN
cord-000079-533xlisc	95	15	.	.	PUNCT
cord-000079-533xlisc	96	1	brains	brain	NOUN
cord-000079-533xlisc	96	2	were	be	AUX
cord-000079-533xlisc	96	3	removed	remove	VERB
cord-000079-533xlisc	96	4	,	,	PUNCT
cord-000079-533xlisc	96	5	suspended	suspend	VERB
cord-000079-533xlisc	96	6	in	in	ADP
cord-000079-533xlisc	96	7	30	30	NUM
cord-000079-533xlisc	96	8	%	%	NOUN
cord-000079-533xlisc	96	9	sucrose	sucrose	NOUN
cord-000079-533xlisc	96	10	for	for	ADP
cord-000079-533xlisc	96	11	three	three	NUM
cord-000079-533xlisc	96	12	days	day	NOUN
cord-000079-533xlisc	96	13	,	,	PUNCT
cord-000079-533xlisc	96	14	and	and	CCONJ
cord-000079-533xlisc	96	15	then	then	ADV
cord-000079-533xlisc	96	16	snap	snap	VERB
cord-000079-533xlisc	96	17	frozen	freeze	VERB
cord-000079-533xlisc	96	18	in	in	ADP
cord-000079-533xlisc	96	19	isopentane	isopentane	PROPN
cord-000079-533xlisc	96	20	chilled	chill	VERB
cord-000079-533xlisc	96	21	with	with	ADP
cord-000079-533xlisc	96	22	dry	dry	ADJ
cord-000079-533xlisc	96	23	ice	ice	NOUN
cord-000079-533xlisc	96	24	.	.	PUNCT
cord-000079-533xlisc	97	1	coronal	coronal	ADJ
cord-000079-533xlisc	97	2	sections	section	NOUN
cord-000079-533xlisc	97	3	(	(	PUNCT
cord-000079-533xlisc	97	4	12	12	NUM
cord-000079-533xlisc	97	5	mm	mm	NOUN
cord-000079-533xlisc	97	6	)	)	PUNCT
cord-000079-533xlisc	97	7	were	be	AUX
cord-000079-533xlisc	97	8	prepared	prepare	VERB
cord-000079-533xlisc	97	9	on	on	ADP
cord-000079-533xlisc	97	10	a	a	DET
cord-000079-533xlisc	97	11	cryostat	cryostat	NOUN
cord-000079-533xlisc	97	12	.	.	PUNCT
cord-000079-533xlisc	98	1	for	for	ADP
cord-000079-533xlisc	98	2	immunofluorescence	immunofluorescence	NOUN
cord-000079-533xlisc	98	3	analysis	analysis	NOUN
cord-000079-533xlisc	98	4	,	,	PUNCT
cord-000079-533xlisc	98	5	sections	section	NOUN
cord-000079-533xlisc	98	6	were	be	AUX
cord-000079-533xlisc	98	7	stained	stain	VERB
cord-000079-533xlisc	98	8	with	with	ADP
cord-000079-533xlisc	98	9	human	human	ADJ
cord-000079-533xlisc	98	10	-	-	PUNCT
cord-000079-533xlisc	98	11	specific	specific	ADJ
cord-000079-533xlisc	98	12	anti	anti	ADJ
cord-000079-533xlisc	98	13	-	-	ADJ
cord-000079-533xlisc	98	14	nestin	nestin	ADJ
cord-000079-533xlisc	98	15	antibodies	antibody	NOUN
cord-000079-533xlisc	98	16	(	(	PUNCT
cord-000079-533xlisc	98	17	millipore	millipore	PROPN
cord-000079-533xlisc	98	18	)	)	PUNCT
cord-000079-533xlisc	98	19	for	for	ADP
cord-000079-533xlisc	98	20	human	human	ADJ
cord-000079-533xlisc	98	21	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	98	22	cells	cell	NOUN
cord-000079-533xlisc	98	23	,	,	PUNCT
cord-000079-533xlisc	98	24	mouse	mouse	NOUN
cord-000079-533xlisc	98	25	-	-	PUNCT
cord-000079-533xlisc	98	26	anti	anti	ADJ
cord-000079-533xlisc	98	27	-	-	ADJ
cord-000079-533xlisc	98	28	neun	neun	ADJ
cord-000079-533xlisc	98	29	(	(	PUNCT
cord-000079-533xlisc	98	30	millipore	millipore	ADJ
cord-000079-533xlisc	98	31	)	)	PUNCT
cord-000079-533xlisc	98	32	antibodies	antibody	NOUN
cord-000079-533xlisc	98	33	for	for	ADP
cord-000079-533xlisc	98	34	neurons	neuron	NOUN
cord-000079-533xlisc	98	35	,	,	PUNCT
cord-000079-533xlisc	98	36	rat	rat	NOUN
cord-000079-533xlisc	98	37	specific	specific	ADJ
cord-000079-533xlisc	98	38	mouse	mouse	NOUN
cord-000079-533xlisc	98	39	-	-	PUNCT
cord-000079-533xlisc	98	40	anti	anti	ADJ
cord-000079-533xlisc	98	41	-	-	ADJ
cord-000079-533xlisc	98	42	nestin	nestin	ADJ
cord-000079-533xlisc	98	43	antibodies	antibody	NOUN
cord-000079-533xlisc	98	44	(	(	PUNCT
cord-000079-533xlisc	98	45	millipore	millipore	ADJ
cord-000079-533xlisc	98	46	)	)	PUNCT
cord-000079-533xlisc	98	47	for	for	ADP
cord-000079-533xlisc	98	48	astrocytes	astrocyte	NOUN
cord-000079-533xlisc	98	49	and	and	CCONJ
cord-000079-533xlisc	98	50	progenitor	progenitor	NOUN
cord-000079-533xlisc	98	51	cells	cell	NOUN
cord-000079-533xlisc	98	52	.	.	PUNCT
cord-000079-533xlisc	99	1	primary	primary	ADJ
cord-000079-533xlisc	99	2	antibodies	antibody	NOUN
cord-000079-533xlisc	99	3	(	(	PUNCT
cord-000079-533xlisc	99	4	dilution	dilution	NOUN
cord-000079-533xlisc	99	5	1:200	1:200	NUM
cord-000079-533xlisc	99	6	)	)	PUNCT
cord-000079-533xlisc	99	7	were	be	AUX
cord-000079-533xlisc	99	8	incubated	incubate	VERB
cord-000079-533xlisc	99	9	overnight	overnight	ADV
cord-000079-533xlisc	99	10	at	at	ADP
cord-000079-533xlisc	99	11	4uc	4uc	NOUN
cord-000079-533xlisc	99	12	.	.	PUNCT
cord-000079-533xlisc	100	1	biotinylated	biotinylate	VERB
cord-000079-533xlisc	100	2	goat	goat	PROPN
cord-000079-533xlisc	100	3	-	-	PUNCT
cord-000079-533xlisc	100	4	anti	anti	ADJ
cord-000079-533xlisc	100	5	-	-	ADJ
cord-000079-533xlisc	100	6	mouse	mouse	ADJ
cord-000079-533xlisc	100	7	and	and	CCONJ
cord-000079-533xlisc	100	8	goat	goat	PROPN
cord-000079-533xlisc	100	9	-	-	PUNCT
cord-000079-533xlisc	100	10	anti	anti	ADJ
cord-000079-533xlisc	100	11	-	-	ADJ
cord-000079-533xlisc	100	12	rabbit	rabbit	ADJ
cord-000079-533xlisc	100	13	(	(	PUNCT
cord-000079-533xlisc	100	14	vector	vector	NOUN
cord-000079-533xlisc	100	15	laboratories	laboratory	NOUN
cord-000079-533xlisc	100	16	,	,	PUNCT
cord-000079-533xlisc	100	17	burlinghame	burlinghame	NOUN
cord-000079-533xlisc	100	18	,	,	PUNCT
cord-000079-533xlisc	100	19	ca	can	AUX
cord-000079-533xlisc	100	20	)	)	PUNCT
cord-000079-533xlisc	100	21	were	be	AUX
cord-000079-533xlisc	100	22	used	use	VERB
cord-000079-533xlisc	100	23	as	as	ADP
cord-000079-533xlisc	100	24	secondary	secondary	ADJ
cord-000079-533xlisc	100	25	antibodies	antibody	NOUN
cord-000079-533xlisc	100	26	(	(	PUNCT
cord-000079-533xlisc	100	27	dilution	dilution	NOUN
cord-000079-533xlisc	100	28	1:100	1:100	NUM
cord-000079-533xlisc	100	29	)	)	PUNCT
cord-000079-533xlisc	100	30	for	for	ADP
cord-000079-533xlisc	100	31	2	2	NUM
cord-000079-533xlisc	100	32	h	h	NOUN
cord-000079-533xlisc	100	33	at	at	ADP
cord-000079-533xlisc	100	34	room	room	NOUN
cord-000079-533xlisc	100	35	temperature	temperature	NOUN
cord-000079-533xlisc	100	36	.	.	PUNCT
cord-000079-533xlisc	101	1	sections	section	NOUN
cord-000079-533xlisc	101	2	were	be	AUX
cord-000079-533xlisc	101	3	incubated	incubate	VERB
cord-000079-533xlisc	101	4	with	with	ADP
cord-000079-533xlisc	101	5	extravidin	extravidin	ADJ
cord-000079-533xlisc	101	6	-	-	PUNCT
cord-000079-533xlisc	101	7	cy3	cy3	PROPN
cord-000079-533xlisc	101	8	(	(	PUNCT
cord-000079-533xlisc	101	9	sigma	sigma	PROPN
cord-000079-533xlisc	101	10	,	,	PUNCT
cord-000079-533xlisc	101	11	st	st	PROPN
cord-000079-533xlisc	101	12	.	.	PROPN
cord-000079-533xlisc	101	13	louis	louis	PROPN
cord-000079-533xlisc	101	14	,	,	PUNCT
cord-000079-533xlisc	101	15	mo	mo	PROPN
cord-000079-533xlisc	101	16	)	)	PUNCT
cord-000079-533xlisc	101	17	as	as	ADP
cord-000079-533xlisc	101	18	fluorochrome	fluorochrome	NOUN
cord-000079-533xlisc	101	19	(	(	PUNCT
cord-000079-533xlisc	101	20	dilution	dilution	NOUN
cord-000079-533xlisc	101	21	1:200	1:200	NUM
cord-000079-533xlisc	101	22	)	)	PUNCT
cord-000079-533xlisc	101	23	for	for	ADP
cord-000079-533xlisc	101	24	1	1	NUM
cord-000079-533xlisc	101	25	h	h	NOUN
cord-000079-533xlisc	101	26	at	at	ADP
cord-000079-533xlisc	101	27	room	room	NOUN
cord-000079-533xlisc	101	28	temperature	temperature	NOUN
cord-000079-533xlisc	101	29	.	.	PUNCT
cord-000079-533xlisc	102	1	the	the	DET
cord-000079-533xlisc	102	2	sections	section	NOUN
cord-000079-533xlisc	102	3	were	be	AUX
cord-000079-533xlisc	102	4	examined	examine	VERB
cord-000079-533xlisc	102	5	under	under	ADP
cord-000079-533xlisc	102	6	a	a	DET
cord-000079-533xlisc	102	7	fluorescence	fluorescence	ADJ
cord-000079-533xlisc	102	8	microscope	microscope	NOUN
cord-000079-533xlisc	102	9	(	(	PUNCT
cord-000079-533xlisc	102	10	nikon	nikon	PROPN
cord-000079-533xlisc	102	11	)	)	PUNCT
cord-000079-533xlisc	102	12	and	and	CCONJ
cord-000079-533xlisc	102	13	analyzed	analyze	VERB
cord-000079-533xlisc	102	14	by	by	ADP
cord-000079-533xlisc	102	15	confocal	confocal	ADJ
cord-000079-533xlisc	102	16	scanning	scan	VERB
cord-000079-533xlisc	102	17	laser	laser	NOUN
cord-000079-533xlisc	102	18	microscopy	microscopy	NOUN
cord-000079-533xlisc	102	19	(	(	PUNCT
cord-000079-533xlisc	102	20	zeiss	zeiss	X
cord-000079-533xlisc	102	21	,	,	PUNCT
cord-000079-533xlisc	102	22	jena	jena	PROPN
cord-000079-533xlisc	102	23	,	,	PUNCT
cord-000079-533xlisc	102	24	germany	germany	PROPN
cord-000079-533xlisc	102	25	)	)	PUNCT
cord-000079-533xlisc	102	26	.	.	PUNCT
cord-000079-533xlisc	103	1	for	for	ADP
cord-000079-533xlisc	103	2	analysis	analysis	NOUN
cord-000079-533xlisc	103	3	of	of	ADP
cord-000079-533xlisc	103	4	transduction	transduction	NOUN
cord-000079-533xlisc	103	5	efficacy	efficacy	NOUN
cord-000079-533xlisc	103	6	,	,	PUNCT
cord-000079-533xlisc	103	7	consecutive	consecutive	ADJ
cord-000079-533xlisc	103	8	sections	section	NOUN
cord-000079-533xlisc	103	9	(	(	PUNCT
cord-000079-533xlisc	103	10	every	every	PRON
cord-000079-533xlisc	103	11	20.-30	20.-30	NUM
cord-000079-533xlisc	103	12	.	.	PUNCT
cord-000079-533xlisc	103	13	)	)	PUNCT
cord-000079-533xlisc	104	1	throughout	throughout	ADP
cord-000079-533xlisc	104	2	the	the	DET
cord-000079-533xlisc	104	3	tumors	tumor	NOUN
cord-000079-533xlisc	104	4	were	be	AUX
cord-000079-533xlisc	104	5	examined	examine	VERB
cord-000079-533xlisc	104	6	under	under	ADP
cord-000079-533xlisc	104	7	a	a	DET
cord-000079-533xlisc	104	8	fluorescence	fluorescence	ADJ
cord-000079-533xlisc	104	9	microscope	microscope	NOUN
cord-000079-533xlisc	104	10	(	(	PUNCT
cord-000079-533xlisc	104	11	nikon	nikon	PROPN
cord-000079-533xlisc	104	12	)	)	PUNCT
cord-000079-533xlisc	104	13	with	with	ADP
cord-000079-533xlisc	104	14	an	an	DET
cord-000079-533xlisc	104	15	automated	automate	VERB
cord-000079-533xlisc	104	16	stage	stage	NOUN
cord-000079-533xlisc	104	17	using	use	VERB
cord-000079-533xlisc	104	18	106magnification	106magnification	NUM
cord-000079-533xlisc	104	19	.	.	PUNCT
cord-000079-533xlisc	105	1	the	the	DET
cord-000079-533xlisc	105	2	transduction	transduction	NOUN
cord-000079-533xlisc	105	3	volume	volume	NOUN
cord-000079-533xlisc	105	4	was	be	AUX
cord-000079-533xlisc	105	5	calculated	calculate	VERB
cord-000079-533xlisc	105	6	using	use	VERB
cord-000079-533xlisc	105	7	nikon	nikon	PROPN
cord-000079-533xlisc	105	8	lucia	lucia	PROPN
cord-000079-533xlisc	105	9	imaging	imaging	NOUN
cord-000079-533xlisc	105	10	software	software	NOUN
cord-000079-533xlisc	105	11	.	.	PUNCT
cord-000079-533xlisc	106	1	paraffin	paraffin	NOUN
cord-000079-533xlisc	106	2	embedded	embed	VERB
cord-000079-533xlisc	106	3	formalin	formalin	ADJ
cord-000079-533xlisc	106	4	-	-	PUNCT
cord-000079-533xlisc	106	5	fixed	fix	VERB
cord-000079-533xlisc	106	6	tissue	tissue	NOUN
cord-000079-533xlisc	106	7	sections	section	NOUN
cord-000079-533xlisc	106	8	from	from	ADP
cord-000079-533xlisc	106	9	rat	rat	NOUN
cord-000079-533xlisc	106	10	brain	brain	NOUN
cord-000079-533xlisc	106	11	and	and	CCONJ
cord-000079-533xlisc	106	12	patient	patient	NOUN
cord-000079-533xlisc	106	13	material	material	NOUN
cord-000079-533xlisc	106	14	were	be	AUX
cord-000079-533xlisc	106	15	placed	place	VERB
cord-000079-533xlisc	106	16	in	in	ADP
cord-000079-533xlisc	106	17	xylene	xylene	PROPN
cord-000079-533xlisc	106	18	bath	bath	NOUN
cord-000079-533xlisc	106	19	for	for	ADP
cord-000079-533xlisc	106	20	263	263	NUM
cord-000079-533xlisc	106	21	minutes	minute	NOUN
cord-000079-533xlisc	106	22	,	,	PUNCT
cord-000079-533xlisc	106	23	absolute	absolute	ADJ
cord-000079-533xlisc	106	24	ethanol	ethanol	NOUN
cord-000079-533xlisc	106	25	263	263	NUM
cord-000079-533xlisc	106	26	minutes	minute	NOUN
cord-000079-533xlisc	106	27	,	,	PUNCT
cord-000079-533xlisc	106	28	96	96	NUM
cord-000079-533xlisc	106	29	%	%	NOUN
cord-000079-533xlisc	106	30	ethanol	ethanol	NOUN
cord-000079-533xlisc	106	31	262	262	NUM
cord-000079-533xlisc	106	32	minutes	minute	NOUN
cord-000079-533xlisc	106	33	and	and	CCONJ
cord-000079-533xlisc	106	34	finally	finally	ADV
cord-000079-533xlisc	106	35	in	in	ADP
cord-000079-533xlisc	106	36	distilled	distilled	ADJ
cord-000079-533xlisc	106	37	water	water	NOUN
cord-000079-533xlisc	106	38	for	for	ADP
cord-000079-533xlisc	106	39	30	30	NUM
cord-000079-533xlisc	106	40	seconds	second	NOUN
cord-000079-533xlisc	106	41	for	for	ADP
cord-000079-533xlisc	106	42	removal	removal	NOUN
cord-000079-533xlisc	106	43	of	of	ADP
cord-000079-533xlisc	106	44	paraffin	paraffin	NOUN
cord-000079-533xlisc	106	45	and	and	CCONJ
cord-000079-533xlisc	106	46	rehydration	rehydration	NOUN
cord-000079-533xlisc	106	47	.	.	PUNCT
cord-000079-533xlisc	107	1	epitope	epitope	PROPN
cord-000079-533xlisc	107	2	retrieval	retrieval	PROPN
cord-000079-533xlisc	107	3	was	be	AUX
cord-000079-533xlisc	107	4	performed	perform	VERB
cord-000079-533xlisc	107	5	by	by	ADP
cord-000079-533xlisc	107	6	heating	heat	VERB
cord-000079-533xlisc	107	7	the	the	DET
cord-000079-533xlisc	107	8	sections	section	NOUN
cord-000079-533xlisc	107	9	at	at	ADP
cord-000079-533xlisc	107	10	99uc	99uc	NOUN
cord-000079-533xlisc	107	11	for	for	ADP
cord-000079-533xlisc	107	12	20	20	NUM
cord-000079-533xlisc	107	13	minutes	minute	NOUN
cord-000079-533xlisc	107	14	in	in	ADP
cord-000079-533xlisc	107	15	10	10	NUM
cord-000079-533xlisc	107	16	mm	mm	NOUN
cord-000079-533xlisc	107	17	citrate	citrate	NOUN
cord-000079-533xlisc	107	18	buffer	buffer	NOUN
cord-000079-533xlisc	107	19	at	at	ADP
cord-000079-533xlisc	107	20	ph	ph	NOUN
cord-000079-533xlisc	107	21	6.0	6.0	NUM
cord-000079-533xlisc	107	22	.	.	PUNCT
cord-000079-533xlisc	108	1	the	the	DET
cord-000079-533xlisc	108	2	sections	section	NOUN
cord-000079-533xlisc	108	3	were	be	AUX
cord-000079-533xlisc	108	4	incubated	incubate	VERB
cord-000079-533xlisc	108	5	with	with	ADP
cord-000079-533xlisc	108	6	a	a	DET
cord-000079-533xlisc	108	7	monoclonal	monoclonal	NOUN
cord-000079-533xlisc	108	8	human	human	ADJ
cord-000079-533xlisc	108	9	-	-	PUNCT
cord-000079-533xlisc	108	10	specific	specific	ADJ
cord-000079-533xlisc	108	11	anti	anti	ADJ
cord-000079-533xlisc	108	12	-	-	ADJ
cord-000079-533xlisc	108	13	nestin	nestin	ADJ
cord-000079-533xlisc	108	14	antibody	antibody	NOUN
cord-000079-533xlisc	108	15	1:200	1:200	PROPN
cord-000079-533xlisc	108	16	in	in	ADP
cord-000079-533xlisc	108	17	tbs/1%bsa	tbs/1%bsa	NOUN
cord-000079-533xlisc	108	18	over	over	ADP
cord-000079-533xlisc	108	19	night	night	NOUN
cord-000079-533xlisc	108	20	at	at	ADP
cord-000079-533xlisc	108	21	4uc	4uc	NOUN
cord-000079-533xlisc	108	22	.	.	PUNCT
cord-000079-533xlisc	109	1	a	a	DET
cord-000079-533xlisc	109	2	biotinylated	biotinylate	VERB
cord-000079-533xlisc	109	3	goat	goat	NOUN
cord-000079-533xlisc	109	4	-	-	PUNCT
cord-000079-533xlisc	109	5	anti	anti	ADJ
cord-000079-533xlisc	109	6	-	-	ADJ
cord-000079-533xlisc	109	7	mouse	mouse	ADJ
cord-000079-533xlisc	109	8	antibody	antibody	NOUN
cord-000079-533xlisc	109	9	(	(	PUNCT
cord-000079-533xlisc	109	10	vector	vector	NOUN
cord-000079-533xlisc	109	11	laboratories	laboratory	NOUN
cord-000079-533xlisc	109	12	)	)	PUNCT
cord-000079-533xlisc	109	13	was	be	AUX
cord-000079-533xlisc	109	14	used	use	VERB
cord-000079-533xlisc	109	15	as	as	ADP
cord-000079-533xlisc	109	16	secondary	secondary	ADJ
cord-000079-533xlisc	109	17	antibody	antibody	NOUN
cord-000079-533xlisc	109	18	(	(	PUNCT
cord-000079-533xlisc	109	19	dilution	dilution	NOUN
cord-000079-533xlisc	109	20	1:100	1:100	NUM
cord-000079-533xlisc	109	21	)	)	PUNCT
cord-000079-533xlisc	109	22	for	for	ADP
cord-000079-533xlisc	109	23	1	1	NUM
cord-000079-533xlisc	109	24	h	h	NOUN
cord-000079-533xlisc	109	25	at	at	ADP
cord-000079-533xlisc	109	26	room	room	NOUN
cord-000079-533xlisc	109	27	temperature	temperature	NOUN
cord-000079-533xlisc	109	28	followed	follow	VERB
cord-000079-533xlisc	109	29	by	by	ADP
cord-000079-533xlisc	109	30	abc	abc	PROPN
cord-000079-533xlisc	109	31	-	-	PUNCT
cord-000079-533xlisc	109	32	complex	complex	ADJ
cord-000079-533xlisc	109	33	incubation	incubation	NOUN
cord-000079-533xlisc	109	34	for	for	ADP
cord-000079-533xlisc	109	35	30	30	NUM
cord-000079-533xlisc	109	36	min	min	PROPN
cord-000079-533xlisc	109	37	.	.	PROPN
cord-000079-533xlisc	109	38	sections	section	NOUN
cord-000079-533xlisc	109	39	were	be	AUX
cord-000079-533xlisc	109	40	developed	develop	VERB
cord-000079-533xlisc	109	41	with	with	ADP
cord-000079-533xlisc	109	42	with	with	ADP
cord-000079-533xlisc	109	43	393	393	NUM
cord-000079-533xlisc	109	44	-	-	PUNCT
cord-000079-533xlisc	109	45	diaminobenzidine	diaminobenzidine	NOUN
cord-000079-533xlisc	109	46	(	(	PUNCT
cord-000079-533xlisc	109	47	dako	dako	PROPN
cord-000079-533xlisc	109	48	cytomation	cytomation	NOUN
cord-000079-533xlisc	109	49	)	)	PUNCT
cord-000079-533xlisc	109	50	,	,	PUNCT
cord-000079-533xlisc	109	51	following	follow	VERB
cord-000079-533xlisc	109	52	the	the	DET
cord-000079-533xlisc	109	53	manufacturer	manufacturer	NOUN
cord-000079-533xlisc	109	54	's	's	PART
cord-000079-533xlisc	109	55	instructions	instruction	NOUN
cord-000079-533xlisc	109	56	.	.	PUNCT
cord-000079-533xlisc	110	1	using	use	VERB
cord-000079-533xlisc	110	2	a	a	DET
cord-000079-533xlisc	110	3	bruker	bruker	NOUN
cord-000079-533xlisc	110	4	pharmascan	pharmascan	ADJ
cord-000079-533xlisc	110	5	7	7	NUM
cord-000079-533xlisc	110	6	tesla	tesla	NOUN
cord-000079-533xlisc	110	7	mr	mr	PROPN
cord-000079-533xlisc	110	8	scanner	scanner	PROPN
cord-000079-533xlisc	110	9	(	(	PUNCT
cord-000079-533xlisc	110	10	bruker	bruker	PROPN
cord-000079-533xlisc	110	11	biospin	biospin	PROPN
cord-000079-533xlisc	110	12	,	,	PUNCT
cord-000079-533xlisc	110	13	billerica	billerica	PROPN
cord-000079-533xlisc	110	14	,	,	PUNCT
cord-000079-533xlisc	110	15	ma	ma	PROPN
cord-000079-533xlisc	110	16	)	)	PUNCT
cord-000079-533xlisc	110	17	,	,	PUNCT
cord-000079-533xlisc	110	18	axial	axial	ADJ
cord-000079-533xlisc	110	19	t2	t2	PROPN
cord-000079-533xlisc	110	20	-	-	PUNCT
cord-000079-533xlisc	110	21	weighted	weight	VERB
cord-000079-533xlisc	110	22	rare	rare	ADJ
cord-000079-533xlisc	110	23	sequences	sequence	NOUN
cord-000079-533xlisc	110	24	were	be	AUX
cord-000079-533xlisc	110	25	acquired	acquire	VERB
cord-000079-533xlisc	110	26	(	(	PUNCT
cord-000079-533xlisc	110	27	repetition	repetition	NOUN
cord-000079-533xlisc	110	28	time	time	NOUN
cord-000079-533xlisc	110	29	,	,	PUNCT
cord-000079-533xlisc	110	30	4,200	4,200	NUM
cord-000079-533xlisc	110	31	ms	ms	ADJ
cord-000079-533xlisc	110	32	;	;	PUNCT
cord-000079-533xlisc	110	33	echo	echo	ADJ
cord-000079-533xlisc	110	34	time	time	NOUN
cord-000079-533xlisc	110	35	,	,	PUNCT
cord-000079-533xlisc	110	36	36	36	NUM
cord-000079-533xlisc	110	37	ms	ms	ADJ
cord-000079-533xlisc	110	38	;	;	PUNCT
cord-000079-533xlisc	110	39	slice	slice	NOUN
cord-000079-533xlisc	110	40	thickness	thickness	NOUN
cord-000079-533xlisc	110	41	,	,	PUNCT
cord-000079-533xlisc	110	42	1	1	NUM
cord-000079-533xlisc	110	43	mm	mm	NOUN
cord-000079-533xlisc	110	44	;	;	PUNCT
cord-000079-533xlisc	110	45	field	field	NOUN
cord-000079-533xlisc	110	46	of	of	ADP
cord-000079-533xlisc	110	47	view	view	NOUN
cord-000079-533xlisc	110	48	,	,	PUNCT
cord-000079-533xlisc	110	49	3.2	3.2	NUM
cord-000079-533xlisc	110	50	cm	cm	NOUN
cord-000079-533xlisc	110	51	;	;	PUNCT
cord-000079-533xlisc	110	52	matrix	matrix	NOUN
cord-000079-533xlisc	110	53	size	size	NOUN
cord-000079-533xlisc	110	54	,	,	PUNCT
cord-000079-533xlisc	110	55	2566256	2566256	NUM
cord-000079-533xlisc	110	56	;	;	PUNCT
cord-000079-533xlisc	110	57	20	20	NUM
cord-000079-533xlisc	110	58	slices	slice	NOUN
cord-000079-533xlisc	110	59	)	)	PUNCT
cord-000079-533xlisc	110	60	.	.	PUNCT
cord-000079-533xlisc	111	1	during	during	ADP
cord-000079-533xlisc	111	2	scanning	scanning	NOUN
cord-000079-533xlisc	111	3	,	,	PUNCT
cord-000079-533xlisc	111	4	the	the	DET
cord-000079-533xlisc	111	5	animals	animal	NOUN
cord-000079-533xlisc	111	6	were	be	AUX
cord-000079-533xlisc	111	7	kept	keep	VERB
cord-000079-533xlisc	111	8	under	under	ADP
cord-000079-533xlisc	111	9	anesthesia	anesthesia	NOUN
cord-000079-533xlisc	111	10	with	with	ADP
cord-000079-533xlisc	111	11	1.5	1.5	NUM
cord-000079-533xlisc	111	12	%	%	NOUN
cord-000079-533xlisc	111	13	isofluorane	isofluorane	NOUN
cord-000079-533xlisc	111	14	(	(	PUNCT
cord-000079-533xlisc	111	15	schering	schering	NOUN
cord-000079-533xlisc	111	16	-	-	PUNCT
cord-000079-533xlisc	111	17	plough	plough	NOUN
cord-000079-533xlisc	111	18	,	,	PUNCT
cord-000079-533xlisc	111	19	kenilworth	kenilworth	PROPN
cord-000079-533xlisc	111	20	,	,	PUNCT
cord-000079-533xlisc	111	21	nj	nj	PROPN
cord-000079-533xlisc	111	22	)	)	PUNCT
cord-000079-533xlisc	111	23	mixed	mix	VERB
cord-000079-533xlisc	111	24	with	with	ADP
cord-000079-533xlisc	111	25	50	50	NUM
cord-000079-533xlisc	111	26	%	%	NOUN
cord-000079-533xlisc	111	27	air	air	NOUN
cord-000079-533xlisc	111	28	and	and	CCONJ
cord-000079-533xlisc	111	29	50	50	NUM
cord-000079-533xlisc	111	30	%	%	NOUN
cord-000079-533xlisc	111	31	o2	o2	PROPN
cord-000079-533xlisc	111	32	.	.	PUNCT
cord-000079-533xlisc	112	1	survival	survival	NOUN
cord-000079-533xlisc	112	2	was	be	AUX
cord-000079-533xlisc	112	3	analyzed	analyze	VERB
cord-000079-533xlisc	112	4	by	by	ADP
cord-000079-533xlisc	112	5	a	a	DET
cord-000079-533xlisc	112	6	log	log	NOUN
cord-000079-533xlisc	112	7	-	-	PUNCT
cord-000079-533xlisc	112	8	rank	rank	NOUN
cord-000079-533xlisc	112	9	test	test	NOUN
cord-000079-533xlisc	112	10	based	base	VERB
cord-000079-533xlisc	112	11	on	on	ADP
cord-000079-533xlisc	112	12	the	the	DET
cord-000079-533xlisc	112	13	kaplan	kaplan	NOUN
cord-000079-533xlisc	112	14	-	-	PUNCT
cord-000079-533xlisc	112	15	meier	mei	ADJ
cord-000079-533xlisc	112	16	test	test	NOUN
cord-000079-533xlisc	112	17	using	use	VERB
cord-000079-533xlisc	112	18	spss	spss	PROPN
cord-000079-533xlisc	112	19	software	software	NOUN
cord-000079-533xlisc	112	20	.	.	PUNCT
cord-000079-533xlisc	113	1	differences	difference	NOUN
cord-000079-533xlisc	113	2	between	between	ADP
cord-000079-533xlisc	113	3	pairs	pair	NOUN
cord-000079-533xlisc	113	4	of	of	ADP
cord-000079-533xlisc	113	5	groups	group	NOUN
cord-000079-533xlisc	113	6	were	be	AUX
cord-000079-533xlisc	113	7	determined	determine	VERB
cord-000079-533xlisc	113	8	by	by	ADP
cord-000079-533xlisc	113	9	the	the	DET
cord-000079-533xlisc	113	10	student	student	NOUN
cord-000079-533xlisc	113	11	's	's	PART
cord-000079-533xlisc	113	12	t	t	PROPN
cord-000079-533xlisc	113	13	-	-	PUNCT
cord-000079-533xlisc	113	14	test	test	NOUN
cord-000079-533xlisc	113	15	.	.	PUNCT
cord-000079-533xlisc	114	1	p	p	PROPN
cord-000079-533xlisc	114	2	values,0.05	values,0.05	PROPN
cord-000079-533xlisc	114	3	were	be	AUX
cord-000079-533xlisc	114	4	considered	consider	VERB
cord-000079-533xlisc	114	5	significant	significant	ADJ
cord-000079-533xlisc	114	6	.	.	PUNCT
cord-000079-533xlisc	115	1	human	human	ADJ
cord-000079-533xlisc	115	2	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	115	3	spheroids	spheroid	NOUN
cord-000079-533xlisc	115	4	derived	derive	VERB
cord-000079-533xlisc	115	5	either	either	CCONJ
cord-000079-533xlisc	115	6	directly	directly	ADV
cord-000079-533xlisc	115	7	from	from	ADP
cord-000079-533xlisc	115	8	the	the	DET
cord-000079-533xlisc	115	9	patient	patient	NOUN
cord-000079-533xlisc	115	10	(	(	PUNCT
cord-000079-533xlisc	115	11	low	low	ADJ
cord-000079-533xlisc	115	12	generation	generation	NOUN
cord-000079-533xlisc	115	13	)	)	PUNCT
cord-000079-533xlisc	115	14	or	or	CCONJ
cord-000079-533xlisc	115	15	from	from	ADP
cord-000079-533xlisc	115	16	serial	serial	ADJ
cord-000079-533xlisc	115	17	in	in	ADP
cord-000079-533xlisc	115	18	vivo	vivo	ADJ
cord-000079-533xlisc	115	19	passages	passage	NOUN
cord-000079-533xlisc	115	20	in	in	ADP
cord-000079-533xlisc	115	21	the	the	DET
cord-000079-533xlisc	115	22	brains	brain	NOUN
cord-000079-533xlisc	115	23	of	of	ADP
cord-000079-533xlisc	115	24	nude	nude	ADJ
cord-000079-533xlisc	115	25	rats	rat	NOUN
cord-000079-533xlisc	115	26	(	(	PUNCT
cord-000079-533xlisc	115	27	high	high	ADJ
cord-000079-533xlisc	115	28	generation	generation	NOUN
cord-000079-533xlisc	115	29	)	)	PUNCT
cord-000079-533xlisc	115	30	,	,	PUNCT
cord-000079-533xlisc	115	31	were	be	AUX
cord-000079-533xlisc	115	32	infected	infect	VERB
cord-000079-533xlisc	115	33	with	with	ADP
cord-000079-533xlisc	115	34	lentiviral	lentiviral	PROPN
cord-000079-533xlisc	115	35	lcmv	lcmv	PROPN
cord-000079-533xlisc	115	36	-	-	PUNCT
cord-000079-533xlisc	115	37	gp	gp	PROPN
cord-000079-533xlisc	115	38	(	(	PUNCT
cord-000079-533xlisc	115	39	5610	5610	NUM
cord-000079-533xlisc	115	40	4	4	NUM
cord-000079-533xlisc	115	41	in	in	ADP
cord-000079-533xlisc	115	42	10	10	NUM
cord-000079-533xlisc	115	43	ml	ml	NOUN
cord-000079-533xlisc	115	44	)	)	PUNCT
cord-000079-533xlisc	115	45	or	or	CCONJ
cord-000079-533xlisc	115	46	vsv	vsv	PROPN
cord-000079-533xlisc	115	47	-	-	PUNCT
cord-000079-533xlisc	115	48	g	g	NOUN
cord-000079-533xlisc	115	49	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	115	50	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	115	51	vectors	vector	NOUN
cord-000079-533xlisc	115	52	(	(	PUNCT
cord-000079-533xlisc	115	53	both	both	CCONJ
cord-000079-533xlisc	115	54	5610	5610	NUM
cord-000079-533xlisc	115	55	4	4	NUM
cord-000079-533xlisc	115	56	particles	particle	NOUN
cord-000079-533xlisc	115	57	in	in	ADP
cord-000079-533xlisc	115	58	10	10	NUM
cord-000079-533xlisc	115	59	ml	ml	NOUN
cord-000079-533xlisc	115	60	)	)	PUNCT
cord-000079-533xlisc	115	61	or	or	CCONJ
cord-000079-533xlisc	115	62	with	with	ADP
cord-000079-533xlisc	115	63	retroviral	retroviral	ADJ
cord-000079-533xlisc	115	64	mlv	mlv	PROPN
cord-000079-533xlisc	115	65	-	-	PUNCT
cord-000079-533xlisc	115	66	based	base	VERB
cord-000079-533xlisc	115	67	vectors	vector	NOUN
cord-000079-533xlisc	115	68	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	115	69	with	with	ADP
cord-000079-533xlisc	115	70	lcmv	lcmv	PROPN
cord-000079-533xlisc	115	71	-	-	PUNCT
cord-000079-533xlisc	115	72	gp	gp	PROPN
cord-000079-533xlisc	115	73	(	(	PUNCT
cord-000079-533xlisc	115	74	1610	1610	NUM
cord-000079-533xlisc	115	75	5	5	NUM
cord-000079-533xlisc	115	76	particles	particle	NOUN
cord-000079-533xlisc	115	77	in	in	ADP
cord-000079-533xlisc	115	78	10	10	NUM
cord-000079-533xlisc	115	79	ml	ml	NOUN
cord-000079-533xlisc	115	80	)	)	PUNCT
cord-000079-533xlisc	115	81	.	.	PUNCT
cord-000079-533xlisc	116	1	the	the	DET
cord-000079-533xlisc	116	2	vectors	vector	NOUN
cord-000079-533xlisc	116	3	were	be	AUX
cord-000079-533xlisc	116	4	prepared	prepare	VERB
cord-000079-533xlisc	116	5	in	in	ADP
cord-000079-533xlisc	116	6	the	the	DET
cord-000079-533xlisc	116	7	same	same	ADJ
cord-000079-533xlisc	116	8	way	way	NOUN
cord-000079-533xlisc	116	9	for	for	ADP
cord-000079-533xlisc	116	10	in	in	ADP
cord-000079-533xlisc	116	11	vitro	vitro	X
cord-000079-533xlisc	116	12	and	and	CCONJ
cord-000079-533xlisc	116	13	in	in	ADP
cord-000079-533xlisc	116	14	vivo	vivo	ADJ
cord-000079-533xlisc	116	15	experiments	experiment	NOUN
cord-000079-533xlisc	116	16	(	(	PUNCT
cord-000079-533xlisc	116	17	see	see	VERB
cord-000079-533xlisc	116	18	materials	material	NOUN
cord-000079-533xlisc	116	19	and	and	CCONJ
cord-000079-533xlisc	116	20	methods	method	NOUN
cord-000079-533xlisc	116	21	)	)	PUNCT
cord-000079-533xlisc	116	22	.	.	PUNCT
cord-000079-533xlisc	117	1	both	both	DET
cord-000079-533xlisc	117	2	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	117	3	vectors	vector	NOUN
cord-000079-533xlisc	117	4	transduced	transduce	VERB
cord-000079-533xlisc	117	5	patient	patient	NOUN
cord-000079-533xlisc	117	6	spheroids	spheroid	NOUN
cord-000079-533xlisc	117	7	and	and	CCONJ
cord-000079-533xlisc	117	8	high	high	ADJ
cord-000079-533xlisc	117	9	generation	generation	NOUN
cord-000079-533xlisc	117	10	spheroids	spheroid	NOUN
cord-000079-533xlisc	117	11	very	very	ADV
cord-000079-533xlisc	117	12	efficiently	efficiently	ADV
cord-000079-533xlisc	117	13	(	(	PUNCT
cord-000079-533xlisc	117	14	figure	figure	NOUN
cord-000079-533xlisc	117	15	1	1	NUM
cord-000079-533xlisc	117	16	)	)	PUNCT
cord-000079-533xlisc	117	17	.	.	PUNCT
cord-000079-533xlisc	118	1	in	in	ADP
cord-000079-533xlisc	118	2	contrast	contrast	NOUN
cord-000079-533xlisc	118	3	,	,	PUNCT
cord-000079-533xlisc	118	4	retroviral	retroviral	ADJ
cord-000079-533xlisc	118	5	vectors	vector	NOUN
cord-000079-533xlisc	118	6	transduced	transduce	VERB
cord-000079-533xlisc	118	7	only	only	ADV
cord-000079-533xlisc	118	8	a	a	DET
cord-000079-533xlisc	118	9	few	few	ADJ
cord-000079-533xlisc	118	10	single	single	ADJ
cord-000079-533xlisc	118	11	cells	cell	NOUN
cord-000079-533xlisc	118	12	in	in	ADP
cord-000079-533xlisc	118	13	high	high	ADJ
cord-000079-533xlisc	118	14	generation	generation	NOUN
cord-000079-533xlisc	118	15	spheroids	spheroid	NOUN
cord-000079-533xlisc	118	16	(	(	PUNCT
cord-000079-533xlisc	118	17	figure	figure	NOUN
cord-000079-533xlisc	118	18	1	1	NUM
cord-000079-533xlisc	118	19	)	)	PUNCT
cord-000079-533xlisc	118	20	and	and	CCONJ
cord-000079-533xlisc	118	21	failed	fail	VERB
cord-000079-533xlisc	118	22	to	to	PART
cord-000079-533xlisc	118	23	transduce	transduce	VERB
cord-000079-533xlisc	118	24	patient	patient	ADJ
cord-000079-533xlisc	118	25	spheroids	spheroid	NOUN
cord-000079-533xlisc	118	26	(	(	PUNCT
cord-000079-533xlisc	118	27	data	datum	NOUN
cord-000079-533xlisc	118	28	not	not	PART
cord-000079-533xlisc	118	29	shown	show	VERB
cord-000079-533xlisc	118	30	)	)	PUNCT
cord-000079-533xlisc	118	31	.	.	PUNCT
cord-000079-533xlisc	119	1	in	in	ADP
cord-000079-533xlisc	119	2	conclusion	conclusion	NOUN
cord-000079-533xlisc	119	3	,	,	PUNCT
cord-000079-533xlisc	119	4	both	both	DET
cord-000079-533xlisc	119	5	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	119	6	vectors	vector	NOUN
cord-000079-533xlisc	119	7	are	be	AUX
cord-000079-533xlisc	119	8	much	much	ADV
cord-000079-533xlisc	119	9	more	more	ADV
cord-000079-533xlisc	119	10	efficient	efficient	ADJ
cord-000079-533xlisc	119	11	in	in	ADP
cord-000079-533xlisc	119	12	transducing	transduce	VERB
cord-000079-533xlisc	119	13	human	human	ADJ
cord-000079-533xlisc	119	14	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	119	15	spheroids	spheroid	NOUN
cord-000079-533xlisc	119	16	in	in	ADP
cord-000079-533xlisc	119	17	vitro	vitro	X
cord-000079-533xlisc	119	18	than	than	ADP
cord-000079-533xlisc	119	19	retroviral	retroviral	ADJ
cord-000079-533xlisc	119	20	vectors	vector	NOUN
cord-000079-533xlisc	119	21	.	.	PUNCT
cord-000079-533xlisc	120	1	to	to	PART
cord-000079-533xlisc	120	2	compare	compare	VERB
cord-000079-533xlisc	120	3	the	the	DET
cord-000079-533xlisc	120	4	transduction	transduction	NOUN
cord-000079-533xlisc	120	5	efficiency	efficiency	NOUN
cord-000079-533xlisc	120	6	of	of	ADP
cord-000079-533xlisc	120	7	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	120	8	and	and	CCONJ
cord-000079-533xlisc	120	9	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	120	10	vectors	vector	NOUN
cord-000079-533xlisc	120	11	in	in	ADP
cord-000079-533xlisc	120	12	vivo	vivo	NOUN
cord-000079-533xlisc	120	13	,	,	PUNCT
cord-000079-533xlisc	120	14	we	we	PRON
cord-000079-533xlisc	120	15	used	use	VERB
cord-000079-533xlisc	120	16	a	a	DET
cord-000079-533xlisc	120	17	xenograft	xenograft	ADJ
cord-000079-533xlisc	120	18	model	model	NOUN
cord-000079-533xlisc	120	19	that	that	PRON
cord-000079-533xlisc	120	20	reflects	reflect	VERB
cord-000079-533xlisc	120	21	the	the	DET
cord-000079-533xlisc	120	22	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	120	23	and	and	CCONJ
cord-000079-533xlisc	120	24	invasive	invasive	ADJ
cord-000079-533xlisc	120	25	features	feature	NOUN
cord-000079-533xlisc	120	26	of	of	ADP
cord-000079-533xlisc	120	27	human	human	ADJ
cord-000079-533xlisc	120	28	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	120	29	in	in	ADP
cord-000079-533xlisc	120	30	situ	situ	NOUN
cord-000079-533xlisc	120	31	.	.	PUNCT
cord-000079-533xlisc	121	1	the	the	DET
cord-000079-533xlisc	121	2	xenograft	xenograft	PROPN
cord-000079-533xlisc	121	3	also	also	ADV
cord-000079-533xlisc	121	4	expresses	express	VERB
cord-000079-533xlisc	121	5	the	the	DET
cord-000079-533xlisc	121	6	neural	neural	ADJ
cord-000079-533xlisc	121	7	progenitor	progenitor	NOUN
cord-000079-533xlisc	121	8	marker	marker	NOUN
cord-000079-533xlisc	121	9	nestin	nestin	NOUN
cord-000079-533xlisc	121	10	and	and	CCONJ
cord-000079-533xlisc	121	11	closely	closely	ADV
cord-000079-533xlisc	121	12	recapitulates	recapitulate	VERB
cord-000079-533xlisc	121	13	the	the	DET
cord-000079-533xlisc	121	14	histology	histology	NOUN
cord-000079-533xlisc	121	15	of	of	ADP
cord-000079-533xlisc	121	16	the	the	DET
cord-000079-533xlisc	121	17	patient	patient	ADJ
cord-000079-533xlisc	121	18	tumor	tumor	NOUN
cord-000079-533xlisc	121	19	(	(	PUNCT
cord-000079-533xlisc	121	20	figure	figure	NOUN
cord-000079-533xlisc	121	21	2	2	NUM
cord-000079-533xlisc	121	22	)	)	PUNCT
cord-000079-533xlisc	121	23	.	.	PUNCT
cord-000079-533xlisc	122	1	the	the	DET
cord-000079-533xlisc	122	2	vectors	vector	NOUN
cord-000079-533xlisc	122	3	were	be	AUX
cord-000079-533xlisc	122	4	injected	inject	VERB
cord-000079-533xlisc	122	5	into	into	ADP
cord-000079-533xlisc	122	6	the	the	DET
cord-000079-533xlisc	122	7	center	center	NOUN
cord-000079-533xlisc	122	8	of	of	ADP
cord-000079-533xlisc	122	9	progressively	progressively	ADV
cord-000079-533xlisc	122	10	growing	grow	VERB
cord-000079-533xlisc	122	11	lesions	lesion	NOUN
cord-000079-533xlisc	122	12	using	use	VERB
cord-000079-533xlisc	122	13	microprocessor	microprocessor	NOUN
cord-000079-533xlisc	122	14	-	-	PUNCT
cord-000079-533xlisc	122	15	controlled	control	VERB
cord-000079-533xlisc	122	16	stereotactic	stereotactic	ADJ
cord-000079-533xlisc	122	17	infusion	infusion	NOUN
cord-000079-533xlisc	122	18	.	.	PUNCT
cord-000079-533xlisc	123	1	the	the	DET
cord-000079-533xlisc	123	2	injection	injection	NOUN
cord-000079-533xlisc	123	3	coordinates	coordinate	NOUN
cord-000079-533xlisc	123	4	were	be	AUX
cord-000079-533xlisc	123	5	estimated	estimate	VERB
cord-000079-533xlisc	123	6	after	after	ADP
cord-000079-533xlisc	123	7	analyzing	analyze	VERB
cord-000079-533xlisc	123	8	mri	mri	NOUN
cord-000079-533xlisc	123	9	images	image	NOUN
cord-000079-533xlisc	123	10	for	for	ADP
cord-000079-533xlisc	123	11	each	each	DET
cord-000079-533xlisc	123	12	individual	individual	ADJ
cord-000079-533xlisc	123	13	lesion	lesion	NOUN
cord-000079-533xlisc	123	14	.	.	PUNCT
cord-000079-533xlisc	124	1	the	the	DET
cord-000079-533xlisc	124	2	injection	injection	NOUN
cord-000079-533xlisc	124	3	volume	volume	NOUN
cord-000079-533xlisc	124	4	applied	apply	VERB
cord-000079-533xlisc	124	5	was	be	AUX
cord-000079-533xlisc	124	6	2610	2610	NUM
cord-000079-533xlisc	124	7	ml	ml	NOUN
cord-000079-533xlisc	124	8	and	and	CCONJ
cord-000079-533xlisc	124	9	the	the	DET
cord-000079-533xlisc	124	10	vector	vector	NOUN
cord-000079-533xlisc	124	11	titre	titre	NOUN
cord-000079-533xlisc	124	12	1610	1610	NUM
cord-000079-533xlisc	124	13	7	7	NUM
cord-000079-533xlisc	124	14	/	/	SYM
cord-000079-533xlisc	124	15	ml	ml	NOUN
cord-000079-533xlisc	124	16	for	for	ADP
cord-000079-533xlisc	124	17	all	all	DET
cord-000079-533xlisc	124	18	vectors	vector	NOUN
cord-000079-533xlisc	124	19	.	.	PUNCT
cord-000079-533xlisc	125	1	transduction	transduction	NOUN
cord-000079-533xlisc	125	2	efficiency	efficiency	NOUN
cord-000079-533xlisc	125	3	was	be	AUX
cord-000079-533xlisc	125	4	evaluated	evaluate	VERB
cord-000079-533xlisc	125	5	7	7	NUM
cord-000079-533xlisc	125	6	days	day	NOUN
cord-000079-533xlisc	125	7	after	after	ADP
cord-000079-533xlisc	125	8	vector	vector	NOUN
cord-000079-533xlisc	125	9	injection	injection	NOUN
cord-000079-533xlisc	125	10	.	.	PUNCT
cord-000079-533xlisc	126	1	both	both	DET
cord-000079-533xlisc	126	2	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	126	3	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	126	4	vectors	vector	NOUN
cord-000079-533xlisc	126	5	showed	show	VERB
cord-000079-533xlisc	126	6	very	very	ADV
cord-000079-533xlisc	126	7	efficient	efficient	ADJ
cord-000079-533xlisc	126	8	transduction	transduction	NOUN
cord-000079-533xlisc	126	9	of	of	ADP
cord-000079-533xlisc	126	10	the	the	DET
cord-000079-533xlisc	126	11	tumors	tumor	NOUN
cord-000079-533xlisc	126	12	(	(	PUNCT
cord-000079-533xlisc	126	13	figure	figure	NOUN
cord-000079-533xlisc	126	14	3a	3a	NUM
cord-000079-533xlisc	126	15	,	,	PUNCT
cord-000079-533xlisc	126	16	d	d	NOUN
cord-000079-533xlisc	126	17	)	)	PUNCT
cord-000079-533xlisc	126	18	.	.	PUNCT
cord-000079-533xlisc	127	1	when	when	SCONJ
cord-000079-533xlisc	127	2	analyzed	analyze	VERB
cord-000079-533xlisc	127	3	at	at	ADP
cord-000079-533xlisc	127	4	higher	high	ADJ
cord-000079-533xlisc	127	5	magnification	magnification	NOUN
cord-000079-533xlisc	127	6	,	,	PUNCT
cord-000079-533xlisc	127	7	both	both	PRON
cord-000079-533xlisc	127	8	lcmv	lcmv	PROPN
cord-000079-533xlisc	127	9	-	-	PUNCT
cord-000079-533xlisc	127	10	gp	gp	PROPN
cord-000079-533xlisc	127	11	and	and	CCONJ
cord-000079-533xlisc	127	12	vsv	vsv	PROPN
cord-000079-533xlisc	127	13	-	-	PUNCT
cord-000079-533xlisc	127	14	g	g	NOUN
cord-000079-533xlisc	127	15	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	127	16	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	127	17	vectors	vector	NOUN
cord-000079-533xlisc	127	18	showed	show	VERB
cord-000079-533xlisc	127	19	efficient	efficient	ADJ
cord-000079-533xlisc	127	20	transgene	transgene	NOUN
cord-000079-533xlisc	127	21	delivery	delivery	NOUN
cord-000079-533xlisc	127	22	to	to	ADP
cord-000079-533xlisc	127	23	nestin	nestin	NOUN
cord-000079-533xlisc	127	24	-	-	PUNCT
cord-000079-533xlisc	127	25	positive	positive	ADJ
cord-000079-533xlisc	127	26	tumor	tumor	NOUN
cord-000079-533xlisc	127	27	cells	cell	NOUN
cord-000079-533xlisc	127	28	in	in	ADP
cord-000079-533xlisc	127	29	solid	solid	ADJ
cord-000079-533xlisc	127	30	(	(	PUNCT
cord-000079-533xlisc	127	31	figure	figure	NOUN
cord-000079-533xlisc	127	32	3b	3b	NOUN
cord-000079-533xlisc	127	33	,	,	PUNCT
cord-000079-533xlisc	127	34	e	e	NOUN
cord-000079-533xlisc	127	35	)	)	PUNCT
cord-000079-533xlisc	127	36	and	and	CCONJ
cord-000079-533xlisc	127	37	invasive	invasive	ADJ
cord-000079-533xlisc	127	38	tumor	tumor	NOUN
cord-000079-533xlisc	127	39	areas	area	NOUN
cord-000079-533xlisc	127	40	(	(	PUNCT
cord-000079-533xlisc	127	41	figure	figure	NOUN
cord-000079-533xlisc	127	42	3c	3c	NUM
cord-000079-533xlisc	127	43	,	,	PUNCT
cord-000079-533xlisc	127	44	f	f	NUM
cord-000079-533xlisc	127	45	)	)	PUNCT
cord-000079-533xlisc	127	46	.	.	PUNCT
cord-000079-533xlisc	128	1	in	in	ADP
cord-000079-533xlisc	128	2	contrast	contrast	NOUN
cord-000079-533xlisc	128	3	,	,	PUNCT
cord-000079-533xlisc	128	4	the	the	DET
cord-000079-533xlisc	128	5	retroviral	retroviral	ADJ
cord-000079-533xlisc	128	6	vector	vector	NOUN
cord-000079-533xlisc	128	7	only	only	ADV
cord-000079-533xlisc	128	8	transduced	transduce	VERB
cord-000079-533xlisc	128	9	a	a	DET
cord-000079-533xlisc	128	10	few	few	ADJ
cord-000079-533xlisc	128	11	scattered	scatter	VERB
cord-000079-533xlisc	128	12	tumor	tumor	NOUN
cord-000079-533xlisc	128	13	cells	cell	NOUN
cord-000079-533xlisc	128	14	near	near	ADP
cord-000079-533xlisc	128	15	the	the	DET
cord-000079-533xlisc	128	16	injection	injection	NOUN
cord-000079-533xlisc	128	17	site	site	NOUN
cord-000079-533xlisc	128	18	(	(	PUNCT
cord-000079-533xlisc	128	19	figure	figure	NOUN
cord-000079-533xlisc	128	20	3	3	NUM
cord-000079-533xlisc	128	21	g	g	NOUN
cord-000079-533xlisc	128	22	,	,	PUNCT
cord-000079-533xlisc	128	23	h	h	PROPN
cord-000079-533xlisc	128	24	)	)	PUNCT
cord-000079-533xlisc	128	25	.	.	PUNCT
cord-000079-533xlisc	129	1	for	for	ADP
cord-000079-533xlisc	129	2	a	a	DET
cord-000079-533xlisc	129	3	quantitative	quantitative	ADJ
cord-000079-533xlisc	129	4	comparison	comparison	NOUN
cord-000079-533xlisc	129	5	of	of	ADP
cord-000079-533xlisc	129	6	transduction	transduction	NOUN
cord-000079-533xlisc	129	7	efficiency	efficiency	NOUN
cord-000079-533xlisc	129	8	between	between	ADP
cord-000079-533xlisc	129	9	the	the	DET
cord-000079-533xlisc	129	10	two	two	NUM
cord-000079-533xlisc	129	11	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	129	12	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	129	13	vectors	vector	NOUN
cord-000079-533xlisc	129	14	,	,	PUNCT
cord-000079-533xlisc	129	15	the	the	DET
cord-000079-533xlisc	129	16	gfp	gfp	NOUN
cord-000079-533xlisc	129	17	-	-	PUNCT
cord-000079-533xlisc	129	18	positive	positive	ADJ
cord-000079-533xlisc	129	19	areas	area	NOUN
cord-000079-533xlisc	129	20	were	be	AUX
cord-000079-533xlisc	129	21	measured	measure	VERB
cord-000079-533xlisc	129	22	on	on	ADP
cord-000079-533xlisc	129	23	histological	histological	ADJ
cord-000079-533xlisc	129	24	slides	slide	NOUN
cord-000079-533xlisc	129	25	(	(	PUNCT
cord-000079-533xlisc	129	26	see	see	VERB
cord-000079-533xlisc	129	27	material	material	NOUN
cord-000079-533xlisc	129	28	and	and	CCONJ
cord-000079-533xlisc	129	29	methods	method	NOUN
cord-000079-533xlisc	129	30	)	)	PUNCT
cord-000079-533xlisc	129	31	.	.	PUNCT
cord-000079-533xlisc	130	1	the	the	DET
cord-000079-533xlisc	130	2	total	total	ADJ
cord-000079-533xlisc	130	3	volume	volume	NOUN
cord-000079-533xlisc	130	4	of	of	ADP
cord-000079-533xlisc	130	5	transduced	transduced	ADJ
cord-000079-533xlisc	130	6	tumor	tumor	NOUN
cord-000079-533xlisc	130	7	tissue	tissue	NOUN
cord-000079-533xlisc	130	8	was	be	AUX
cord-000079-533xlisc	130	9	7.0563.51	7.0563.51	NUM
cord-000079-533xlisc	130	10	mm	mm	NOUN
cord-000079-533xlisc	130	11	3	3	NUM
cord-000079-533xlisc	130	12	for	for	ADP
cord-000079-533xlisc	130	13	lcmv	lcmv	PROPN
cord-000079-533xlisc	130	14	-	-	PUNCT
cord-000079-533xlisc	130	15	gp	gp	NOUN
cord-000079-533xlisc	130	16	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	130	17	vectors	vector	NOUN
cord-000079-533xlisc	130	18	and	and	CCONJ
cord-000079-533xlisc	130	19	4.0562.04	4.0562.04	NUM
cord-000079-533xlisc	130	20	mm	mm	NOUN
cord-000079-533xlisc	130	21	3	3	NUM
cord-000079-533xlisc	130	22	for	for	ADP
cord-000079-533xlisc	130	23	vsv	vsv	PROPN
cord-000079-533xlisc	130	24	-	-	PUNCT
cord-000079-533xlisc	130	25	g	g	NOUN
cord-000079-533xlisc	130	26	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	130	27	vectors	vector	NOUN
cord-000079-533xlisc	130	28	(	(	PUNCT
cord-000079-533xlisc	130	29	figure	figure	NOUN
cord-000079-533xlisc	130	30	3i	3i	NOUN
cord-000079-533xlisc	130	31	)	)	PUNCT
cord-000079-533xlisc	130	32	.	.	PUNCT
cord-000079-533xlisc	131	1	although	although	SCONJ
cord-000079-533xlisc	131	2	there	there	PRON
cord-000079-533xlisc	131	3	was	be	VERB
cord-000079-533xlisc	131	4	a	a	DET
cord-000079-533xlisc	131	5	difference	difference	NOUN
cord-000079-533xlisc	131	6	in	in	ADP
cord-000079-533xlisc	131	7	the	the	DET
cord-000079-533xlisc	131	8	mean	mean	NOUN
cord-000079-533xlisc	131	9	,	,	PUNCT
cord-000079-533xlisc	131	10	it	it	PRON
cord-000079-533xlisc	131	11	was	be	AUX
cord-000079-533xlisc	131	12	not	not	PART
cord-000079-533xlisc	131	13	statistically	statistically	ADV
cord-000079-533xlisc	131	14	significant	significant	ADJ
cord-000079-533xlisc	131	15	(	(	PUNCT
cord-000079-533xlisc	131	16	p	p	NOUN
cord-000079-533xlisc	131	17	=	=	X
cord-000079-533xlisc	131	18	0.269	0.269	NUM
cord-000079-533xlisc	131	19	)	)	PUNCT
cord-000079-533xlisc	131	20	due	due	ADP
cord-000079-533xlisc	131	21	to	to	ADP
cord-000079-533xlisc	131	22	high	high	ADJ
cord-000079-533xlisc	131	23	interindividual	interindividual	ADJ
cord-000079-533xlisc	131	24	differences	difference	NOUN
cord-000079-533xlisc	131	25	(	(	PUNCT
cord-000079-533xlisc	131	26	standard	standard	ADJ
cord-000079-533xlisc	131	27	deviations	deviation	NOUN
cord-000079-533xlisc	131	28	)	)	PUNCT
cord-000079-533xlisc	131	29	.	.	PUNCT
cord-000079-533xlisc	132	1	to	to	PART
cord-000079-533xlisc	132	2	analyze	analyze	VERB
cord-000079-533xlisc	132	3	transduction	transduction	NOUN
cord-000079-533xlisc	132	4	specificity	specificity	NOUN
cord-000079-533xlisc	132	5	,	,	PUNCT
cord-000079-533xlisc	132	6	histological	histological	ADJ
cord-000079-533xlisc	132	7	sections	section	NOUN
cord-000079-533xlisc	132	8	of	of	ADP
cord-000079-533xlisc	132	9	invasive	invasive	ADJ
cord-000079-533xlisc	132	10	tumor	tumor	NOUN
cord-000079-533xlisc	132	11	areas	area	NOUN
cord-000079-533xlisc	132	12	were	be	AUX
cord-000079-533xlisc	132	13	stained	stain	VERB
cord-000079-533xlisc	132	14	for	for	ADP
cord-000079-533xlisc	132	15	rat	rat	NOUN
cord-000079-533xlisc	132	16	specific	specific	ADJ
cord-000079-533xlisc	132	17	markers	marker	NOUN
cord-000079-533xlisc	132	18	neun	neun	PROPN
cord-000079-533xlisc	132	19	(	(	PUNCT
cord-000079-533xlisc	132	20	for	for	ADP
cord-000079-533xlisc	132	21	neurons	neuron	NOUN
cord-000079-533xlisc	132	22	)	)	PUNCT
cord-000079-533xlisc	132	23	and	and	CCONJ
cord-000079-533xlisc	132	24	nestin	nestin	NOUN
cord-000079-533xlisc	132	25	(	(	PUNCT
cord-000079-533xlisc	132	26	for	for	ADP
cord-000079-533xlisc	132	27	astrocytes	astrocyte	NOUN
cord-000079-533xlisc	132	28	and	and	CCONJ
cord-000079-533xlisc	132	29	progenitor	progenitor	NOUN
cord-000079-533xlisc	132	30	cells	cell	NOUN
cord-000079-533xlisc	132	31	)	)	PUNCT
cord-000079-533xlisc	132	32	.	.	PUNCT
cord-000079-533xlisc	133	1	lcmv	lcmv	PROPN
cord-000079-533xlisc	133	2	-	-	PUNCT
cord-000079-533xlisc	133	3	gp	gp	PROPN
cord-000079-533xlisc	133	4	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	133	5	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	133	6	vectors	vector	NOUN
cord-000079-533xlisc	133	7	exclusively	exclusively	ADV
cord-000079-533xlisc	133	8	transduced	transduce	VERB
cord-000079-533xlisc	133	9	tumor	tumor	NOUN
cord-000079-533xlisc	133	10	cells	cell	NOUN
cord-000079-533xlisc	133	11	in	in	ADP
cord-000079-533xlisc	133	12	all	all	DET
cord-000079-533xlisc	133	13	invasive	invasive	ADJ
cord-000079-533xlisc	133	14	areas	area	NOUN
cord-000079-533xlisc	133	15	(	(	PUNCT
cord-000079-533xlisc	133	16	figure	figure	NOUN
cord-000079-533xlisc	133	17	4a	4a	NOUN
cord-000079-533xlisc	133	18	)	)	PUNCT
cord-000079-533xlisc	133	19	,	,	PUNCT
cord-000079-533xlisc	133	20	while	while	SCONJ
cord-000079-533xlisc	133	21	normal	normal	ADJ
cord-000079-533xlisc	133	22	brain	brain	NOUN
cord-000079-533xlisc	133	23	cells	cell	NOUN
cord-000079-533xlisc	133	24	were	be	AUX
cord-000079-533xlisc	133	25	not	not	PART
cord-000079-533xlisc	133	26	transduced	transduce	VERB
cord-000079-533xlisc	133	27	(	(	PUNCT
cord-000079-533xlisc	133	28	figure	figure	NOUN
cord-000079-533xlisc	133	29	4b	4b	PROPN
cord-000079-533xlisc	133	30	,	,	PUNCT
cord-000079-533xlisc	133	31	c	c	NOUN
cord-000079-533xlisc	133	32	)	)	PUNCT
cord-000079-533xlisc	133	33	.	.	PUNCT
cord-000079-533xlisc	134	1	also	also	ADV
cord-000079-533xlisc	134	2	vsv	vsv	PROPN
cord-000079-533xlisc	134	3	-	-	PROPN
cord-000079-533xlisc	134	4	g	g	NOUN
cord-000079-533xlisc	134	5	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	134	6	vectors	vector	NOUN
cord-000079-533xlisc	134	7	showed	show	VERB
cord-000079-533xlisc	134	8	specific	specific	ADJ
cord-000079-533xlisc	134	9	transduction	transduction	NOUN
cord-000079-533xlisc	134	10	of	of	ADP
cord-000079-533xlisc	134	11	tumor	tumor	NOUN
cord-000079-533xlisc	134	12	cells	cell	NOUN
cord-000079-533xlisc	134	13	in	in	ADP
cord-000079-533xlisc	134	14	some	some	DET
cord-000079-533xlisc	134	15	invasive	invasive	ADJ
cord-000079-533xlisc	134	16	areas	area	NOUN
cord-000079-533xlisc	134	17	(	(	PUNCT
cord-000079-533xlisc	134	18	figure	figure	VERB
cord-000079-533xlisc	134	19	4d	4d	PROPN
cord-000079-533xlisc	134	20	,	,	PUNCT
cord-000079-533xlisc	134	21	e	e	PROPN
cord-000079-533xlisc	134	22	)	)	PUNCT
cord-000079-533xlisc	134	23	,	,	PUNCT
cord-000079-533xlisc	134	24	however	however	ADV
cord-000079-533xlisc	134	25	,	,	PUNCT
cord-000079-533xlisc	134	26	they	they	PRON
cord-000079-533xlisc	134	27	also	also	ADV
cord-000079-533xlisc	134	28	transduced	transduce	VERB
cord-000079-533xlisc	134	29	a	a	DET
cord-000079-533xlisc	134	30	few	few	ADJ
cord-000079-533xlisc	134	31	host	host	NOUN
cord-000079-533xlisc	134	32	brain	brain	NOUN
cord-000079-533xlisc	134	33	cells	cell	NOUN
cord-000079-533xlisc	134	34	at	at	ADP
cord-000079-533xlisc	134	35	other	other	ADJ
cord-000079-533xlisc	134	36	sites	site	NOUN
cord-000079-533xlisc	134	37	(	(	PUNCT
cord-000079-533xlisc	134	38	figure	figure	NOUN
cord-000079-533xlisc	134	39	4g	4g	NUM
cord-000079-533xlisc	134	40	,	,	PUNCT
cord-000079-533xlisc	134	41	h	h	PROPN
cord-000079-533xlisc	134	42	)	)	PUNCT
cord-000079-533xlisc	134	43	.	.	PUNCT
cord-000079-533xlisc	135	1	to	to	PART
cord-000079-533xlisc	135	2	analyze	analyze	VERB
cord-000079-533xlisc	135	3	the	the	DET
cord-000079-533xlisc	135	4	potential	potential	NOUN
cord-000079-533xlisc	135	5	of	of	ADP
cord-000079-533xlisc	135	6	both	both	DET
cord-000079-533xlisc	135	7	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	135	8	vectors	vector	NOUN
cord-000079-533xlisc	135	9	to	to	PART
cord-000079-533xlisc	135	10	infect	infect	VERB
cord-000079-533xlisc	135	11	cancer	cancer	NOUN
cord-000079-533xlisc	135	12	stem	stem	NOUN
cord-000079-533xlisc	135	13	-	-	PUNCT
cord-000079-533xlisc	135	14	like	like	ADJ
cord-000079-533xlisc	135	15	cells	cell	NOUN
cord-000079-533xlisc	135	16	,	,	PUNCT
cord-000079-533xlisc	135	17	transduced	transduce	VERB
cord-000079-533xlisc	135	18	tumors	tumor	NOUN
cord-000079-533xlisc	135	19	were	be	AUX
cord-000079-533xlisc	135	20	enzymatically	enzymatically	ADV
cord-000079-533xlisc	135	21	dissociated	dissociate	VERB
cord-000079-533xlisc	135	22	and	and	CCONJ
cord-000079-533xlisc	135	23	cd133	cd133	ADJ
cord-000079-533xlisc	135	24	expression	expression	NOUN
cord-000079-533xlisc	135	25	was	be	AUX
cord-000079-533xlisc	135	26	measured	measure	VERB
cord-000079-533xlisc	135	27	by	by	ADP
cord-000079-533xlisc	135	28	flow	flow	NOUN
cord-000079-533xlisc	135	29	cytometry	cytometry	NOUN
cord-000079-533xlisc	135	30	.	.	PUNCT
cord-000079-533xlisc	136	1	both	both	DET
cord-000079-533xlisc	136	2	vectors	vector	NOUN
cord-000079-533xlisc	136	3	transduced	transduce	VERB
cord-000079-533xlisc	136	4	cd133	cd133	PROPN
cord-000079-533xlisc	136	5	-	-	PUNCT
cord-000079-533xlisc	136	6	positive	positive	ADJ
cord-000079-533xlisc	136	7	and	and	CCONJ
cord-000079-533xlisc	136	8	cd133	cd133	ADV
cord-000079-533xlisc	136	9	-	-	PUNCT
cord-000079-533xlisc	136	10	negative	negative	ADJ
cord-000079-533xlisc	136	11	cells	cell	NOUN
cord-000079-533xlisc	136	12	(	(	PUNCT
cord-000079-533xlisc	136	13	figure	figure	NOUN
cord-000079-533xlisc	136	14	5a	5a	NUM
cord-000079-533xlisc	136	15	)	)	PUNCT
cord-000079-533xlisc	136	16	.	.	PUNCT
cord-000079-533xlisc	137	1	although	although	SCONJ
cord-000079-533xlisc	137	2	there	there	PRON
cord-000079-533xlisc	137	3	were	be	VERB
cord-000079-533xlisc	137	4	high	high	ADJ
cord-000079-533xlisc	137	5	interindividual	interindividual	ADJ
cord-000079-533xlisc	137	6	differences	difference	NOUN
cord-000079-533xlisc	137	7	in	in	ADP
cord-000079-533xlisc	137	8	the	the	DET
cord-000079-533xlisc	137	9	fraction	fraction	NOUN
cord-000079-533xlisc	137	10	of	of	ADP
cord-000079-533xlisc	137	11	total	total	ADJ
cord-000079-533xlisc	137	12	cd133	cd133	ADV
cord-000079-533xlisc	137	13	-	-	PUNCT
cord-000079-533xlisc	137	14	positive	positive	ADJ
cord-000079-533xlisc	137	15	tumor	tumor	NOUN
cord-000079-533xlisc	137	16	cells	cell	NOUN
cord-000079-533xlisc	137	17	in	in	ADP
cord-000079-533xlisc	137	18	the	the	DET
cord-000079-533xlisc	137	19	different	different	ADJ
cord-000079-533xlisc	137	20	xenografts	xenograft	NOUN
cord-000079-533xlisc	137	21	,	,	PUNCT
cord-000079-533xlisc	137	22	both	both	DET
cord-000079-533xlisc	137	23	vectors	vector	NOUN
cord-000079-533xlisc	137	24	showed	show	VERB
cord-000079-533xlisc	137	25	similar	similar	ADJ
cord-000079-533xlisc	137	26	efficiency	efficiency	NOUN
cord-000079-533xlisc	137	27	in	in	ADP
cord-000079-533xlisc	137	28	transducing	transduce	VERB
cord-000079-533xlisc	137	29	cd133	cd133	PROPN
cord-000079-533xlisc	137	30	-	-	PUNCT
cord-000079-533xlisc	137	31	positive	positive	ADJ
cord-000079-533xlisc	137	32	cells	cell	NOUN
cord-000079-533xlisc	137	33	,	,	PUNCT
cord-000079-533xlisc	137	34	which	which	PRON
cord-000079-533xlisc	137	35	was	be	AUX
cord-000079-533xlisc	137	36	slightly	slightly	ADV
cord-000079-533xlisc	137	37	higher	high	ADJ
cord-000079-533xlisc	137	38	than	than	ADP
cord-000079-533xlisc	137	39	the	the	DET
cord-000079-533xlisc	137	40	overall	overall	ADJ
cord-000079-533xlisc	137	41	fraction	fraction	NOUN
cord-000079-533xlisc	137	42	of	of	ADP
cord-000079-533xlisc	137	43	cd133	cd133	PROPN
cord-000079-533xlisc	137	44	-	-	PUNCT
cord-000079-533xlisc	137	45	positive	positive	ADJ
cord-000079-533xlisc	137	46	cells	cell	NOUN
cord-000079-533xlisc	137	47	(	(	PUNCT
cord-000079-533xlisc	137	48	table	table	NOUN
cord-000079-533xlisc	137	49	1	1	NUM
cord-000079-533xlisc	137	50	)	)	PUNCT
cord-000079-533xlisc	137	51	.	.	PUNCT
cord-000079-533xlisc	138	1	the	the	DET
cord-000079-533xlisc	138	2	gfp	gfp	NOUN
cord-000079-533xlisc	138	3	-	-	PUNCT
cord-000079-533xlisc	138	4	positive	positive	ADJ
cord-000079-533xlisc	138	5	cells	cell	NOUN
cord-000079-533xlisc	138	6	from	from	ADP
cord-000079-533xlisc	138	7	tumors	tumor	NOUN
cord-000079-533xlisc	138	8	transduced	transduce	VERB
cord-000079-533xlisc	138	9	with	with	ADP
cord-000079-533xlisc	138	10	lcmv	lcmv	PROPN
cord-000079-533xlisc	138	11	-	-	PUNCT
cord-000079-533xlisc	138	12	gp	gp	PROPN
cord-000079-533xlisc	138	13	or	or	CCONJ
cord-000079-533xlisc	138	14	vsv	vsv	PROPN
cord-000079-533xlisc	138	15	-	-	PUNCT
cord-000079-533xlisc	138	16	g	g	NOUN
cord-000079-533xlisc	138	17	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	138	18	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	138	19	vectors	vector	NOUN
cord-000079-533xlisc	138	20	were	be	AUX
cord-000079-533xlisc	138	21	sorted	sort	VERB
cord-000079-533xlisc	138	22	and	and	CCONJ
cord-000079-533xlisc	138	23	cultured	cultured	ADJ
cord-000079-533xlisc	138	24	in	in	ADP
cord-000079-533xlisc	138	25	neural	neural	ADJ
cord-000079-533xlisc	138	26	basal	basal	ADJ
cord-000079-533xlisc	138	27	medium	medium	NOUN
cord-000079-533xlisc	138	28	supplemented	supplement	VERB
cord-000079-533xlisc	138	29	with	with	ADP
cord-000079-533xlisc	138	30	egf	egf	NOUN
cord-000079-533xlisc	138	31	and	and	CCONJ
cord-000079-533xlisc	138	32	bfgf	bfgf	PROPN
cord-000079-533xlisc	138	33	.	.	PUNCT
cord-000079-533xlisc	139	1	transduced	transduce	VERB
cord-000079-533xlisc	139	2	tumor	tumor	NOUN
cord-000079-533xlisc	139	3	cells	cell	NOUN
cord-000079-533xlisc	139	4	from	from	ADP
cord-000079-533xlisc	139	5	both	both	DET
cord-000079-533xlisc	139	6	vectors	vector	NOUN
cord-000079-533xlisc	139	7	were	be	AUX
cord-000079-533xlisc	139	8	able	able	ADJ
cord-000079-533xlisc	139	9	to	to	PART
cord-000079-533xlisc	139	10	form	form	VERB
cord-000079-533xlisc	139	11	spheroids	spheroid	NOUN
cord-000079-533xlisc	139	12	(	(	PUNCT
cord-000079-533xlisc	139	13	figure	figure	VERB
cord-000079-533xlisc	139	14	5b	5b	NUM
cord-000079-533xlisc	139	15	,	,	PUNCT
cord-000079-533xlisc	139	16	e	e	NOUN
cord-000079-533xlisc	139	17	)	)	PUNCT
cord-000079-533xlisc	139	18	.	.	PUNCT
cord-000079-533xlisc	140	1	spheroids	spheroid	NOUN
cord-000079-533xlisc	140	2	expressed	express	VERB
cord-000079-533xlisc	140	3	the	the	DET
cord-000079-533xlisc	140	4	stem	stem	NOUN
cord-000079-533xlisc	140	5	cell	cell	NOUN
cord-000079-533xlisc	140	6	markers	marker	NOUN
cord-000079-533xlisc	140	7	nestin	nestin	ADV
cord-000079-533xlisc	140	8	and	and	CCONJ
cord-000079-533xlisc	140	9	sox2	sox2	PROPN
cord-000079-533xlisc	140	10	(	(	PUNCT
cord-000079-533xlisc	140	11	figure	figure	NOUN
cord-000079-533xlisc	140	12	5c	5c	PROPN
cord-000079-533xlisc	140	13	,	,	PUNCT
cord-000079-533xlisc	140	14	d	d	PROPN
cord-000079-533xlisc	140	15	,	,	PUNCT
cord-000079-533xlisc	140	16	f	f	PROPN
cord-000079-533xlisc	140	17	,	,	PUNCT
cord-000079-533xlisc	140	18	g	g	NOUN
cord-000079-533xlisc	140	19	)	)	PUNCT
cord-000079-533xlisc	140	20	.	.	PUNCT
cord-000079-533xlisc	141	1	sorted	sorted	ADJ
cord-000079-533xlisc	141	2	cells	cell	NOUN
cord-000079-533xlisc	141	3	were	be	AUX
cord-000079-533xlisc	141	4	also	also	ADV
cord-000079-533xlisc	141	5	plated	plate	VERB
cord-000079-533xlisc	141	6	under	under	ADP
cord-000079-533xlisc	141	7	serum	serum	NOUN
cord-000079-533xlisc	141	8	conditions	condition	NOUN
cord-000079-533xlisc	141	9	.	.	PUNCT
cord-000079-533xlisc	142	1	the	the	DET
cord-000079-533xlisc	142	2	cells	cell	NOUN
cord-000079-533xlisc	142	3	continued	continue	VERB
cord-000079-533xlisc	142	4	to	to	PART
cord-000079-533xlisc	142	5	show	show	VERB
cord-000079-533xlisc	142	6	significant	significant	ADJ
cord-000079-533xlisc	142	7	expression	expression	NOUN
cord-000079-533xlisc	142	8	of	of	ADP
cord-000079-533xlisc	142	9	the	the	DET
cord-000079-533xlisc	142	10	stem	stem	NOUN
cord-000079-533xlisc	142	11	cell	cell	NOUN
cord-000079-533xlisc	142	12	markers	marker	NOUN
cord-000079-533xlisc	142	13	nestin	nestin	PROPN
cord-000079-533xlisc	142	14	and	and	CCONJ
cord-000079-533xlisc	142	15	sox2	sox2	PROPN
cord-000079-533xlisc	142	16	,	,	PUNCT
cord-000079-533xlisc	142	17	but	but	CCONJ
cord-000079-533xlisc	142	18	also	also	ADV
cord-000079-533xlisc	142	19	of	of	ADP
cord-000079-533xlisc	142	20	the	the	DET
cord-000079-533xlisc	142	21	differentiation	differentiation	NOUN
cord-000079-533xlisc	142	22	markers	marker	NOUN
cord-000079-533xlisc	142	23	gfap	gfap	ADJ
cord-000079-533xlisc	142	24	and	and	CCONJ
cord-000079-533xlisc	142	25	b	b	NOUN
cord-000079-533xlisc	142	26	-	-	PUNCT
cord-000079-533xlisc	142	27	tubuliniii	tubuliniii	NOUN
cord-000079-533xlisc	142	28	(	(	PUNCT
cord-000079-533xlisc	142	29	figure	figure	NOUN
cord-000079-533xlisc	142	30	5h	5h	NOUN
cord-000079-533xlisc	142	31	-	-	PUNCT
cord-000079-533xlisc	142	32	o	o	PROPN
cord-000079-533xlisc	142	33	)	)	PUNCT
cord-000079-533xlisc	142	34	.	.	PUNCT
cord-000079-533xlisc	143	1	to	to	PART
cord-000079-533xlisc	143	2	evaluate	evaluate	VERB
cord-000079-533xlisc	143	3	the	the	DET
cord-000079-533xlisc	143	4	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	143	5	efficacy	efficacy	NOUN
cord-000079-533xlisc	143	6	of	of	ADP
cord-000079-533xlisc	143	7	both	both	DET
cord-000079-533xlisc	143	8	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	143	9	pseudotyoped	pseudotyope	VERB
cord-000079-533xlisc	143	10	vectors	vector	NOUN
cord-000079-533xlisc	143	11	in	in	ADP
cord-000079-533xlisc	143	12	the	the	DET
cord-000079-533xlisc	143	13	invasive	invasive	ADJ
cord-000079-533xlisc	143	14	xenograft	xenograft	ADJ
cord-000079-533xlisc	143	15	model	model	NOUN
cord-000079-533xlisc	143	16	,	,	PUNCT
cord-000079-533xlisc	143	17	vectors	vector	NOUN
cord-000079-533xlisc	143	18	expressing	express	VERB
cord-000079-533xlisc	143	19	the	the	DET
cord-000079-533xlisc	143	20	suicide	suicide	NOUN
cord-000079-533xlisc	143	21	gene	gene	NOUN
cord-000079-533xlisc	143	22	hsv1	hsv1	PROPN
cord-000079-533xlisc	143	23	-	-	PUNCT
cord-000079-533xlisc	143	24	tk	tk	PROPN
cord-000079-533xlisc	143	25	fused	fuse	VERB
cord-000079-533xlisc	143	26	to	to	ADP
cord-000079-533xlisc	143	27	egfp	egfp	NOUN
cord-000079-533xlisc	143	28	were	be	AUX
cord-000079-533xlisc	143	29	injected	inject	VERB
cord-000079-533xlisc	143	30	into	into	ADP
cord-000079-533xlisc	143	31	established	establish	VERB
cord-000079-533xlisc	143	32	tumors	tumor	NOUN
cord-000079-533xlisc	143	33	when	when	SCONJ
cord-000079-533xlisc	143	34	visible	visible	ADJ
cord-000079-533xlisc	143	35	on	on	ADP
cord-000079-533xlisc	143	36	mri	mri	NOUN
cord-000079-533xlisc	143	37	using	use	VERB
cord-000079-533xlisc	143	38	the	the	DET
cord-000079-533xlisc	143	39	same	same	ADJ
cord-000079-533xlisc	143	40	method	method	NOUN
cord-000079-533xlisc	143	41	as	as	SCONJ
cord-000079-533xlisc	143	42	described	describe	VERB
cord-000079-533xlisc	143	43	for	for	ADP
cord-000079-533xlisc	143	44	the	the	DET
cord-000079-533xlisc	143	45	in	in	ADP
cord-000079-533xlisc	143	46	vivo	vivo	ADJ
cord-000079-533xlisc	143	47	tropism	tropism	PROPN
cord-000079-533xlisc	143	48	study	study	NOUN
cord-000079-533xlisc	143	49	.	.	PUNCT
cord-000079-533xlisc	144	1	the	the	DET
cord-000079-533xlisc	144	2	animals	animal	NOUN
cord-000079-533xlisc	144	3	were	be	AUX
cord-000079-533xlisc	144	4	treated	treat	VERB
cord-000079-533xlisc	144	5	daily	daily	ADV
cord-000079-533xlisc	144	6	with	with	ADP
cord-000079-533xlisc	144	7	50	50	NUM
cord-000079-533xlisc	144	8	mg	mg	NOUN
cord-000079-533xlisc	144	9	/	/	SYM
cord-000079-533xlisc	144	10	kg	kg	NOUN
cord-000079-533xlisc	144	11	ganciclovir	ganciclovir	NOUN
cord-000079-533xlisc	144	12	for	for	ADP
cord-000079-533xlisc	144	13	30	30	NUM
cord-000079-533xlisc	144	14	days	day	NOUN
cord-000079-533xlisc	144	15	starting	start	VERB
cord-000079-533xlisc	144	16	7	7	NUM
cord-000079-533xlisc	144	17	days	day	NOUN
cord-000079-533xlisc	144	18	post	post	NOUN
cord-000079-533xlisc	144	19	vector	vector	NOUN
cord-000079-533xlisc	144	20	injection	injection	NOUN
cord-000079-533xlisc	144	21	.	.	PUNCT
cord-000079-533xlisc	145	1	tumor	tumor	NOUN
cord-000079-533xlisc	145	2	growth	growth	NOUN
cord-000079-533xlisc	145	3	was	be	AUX
cord-000079-533xlisc	145	4	measured	measure	VERB
cord-000079-533xlisc	145	5	every	every	DET
cord-000079-533xlisc	145	6	7	7	NUM
cord-000079-533xlisc	145	7	-	-	SYM
cord-000079-533xlisc	145	8	14	14	NUM
cord-000079-533xlisc	145	9	days	day	NOUN
cord-000079-533xlisc	145	10	by	by	ADP
cord-000079-533xlisc	145	11	mri	mri	PROPN
cord-000079-533xlisc	145	12	.	.	PUNCT
cord-000079-533xlisc	146	1	after	after	ADP
cord-000079-533xlisc	146	2	4	4	NUM
cord-000079-533xlisc	146	3	weeks	week	NOUN
cord-000079-533xlisc	146	4	of	of	ADP
cord-000079-533xlisc	146	5	treatment	treatment	NOUN
cord-000079-533xlisc	146	6	,	,	PUNCT
cord-000079-533xlisc	146	7	7	7	NUM
cord-000079-533xlisc	146	8	out	out	ADP
cord-000079-533xlisc	146	9	of	of	ADP
cord-000079-533xlisc	146	10	8	8	NUM
cord-000079-533xlisc	146	11	animals	animal	NOUN
cord-000079-533xlisc	146	12	in	in	ADP
cord-000079-533xlisc	146	13	both	both	CCONJ
cord-000079-533xlisc	146	14	the	the	DET
cord-000079-533xlisc	146	15	lcmv	lcmv	PROPN
cord-000079-533xlisc	146	16	-	-	PUNCT
cord-000079-533xlisc	146	17	and	and	CCONJ
cord-000079-533xlisc	146	18	the	the	DET
cord-000079-533xlisc	146	19	vsv	vsv	PROPN
cord-000079-533xlisc	146	20	-	-	PUNCT
cord-000079-533xlisc	146	21	pseudotype	pseudotype	ADJ
cord-000079-533xlisc	146	22	treated	treat	VERB
cord-000079-533xlisc	146	23	groups	group	NOUN
cord-000079-533xlisc	146	24	had	have	VERB
cord-000079-533xlisc	146	25	a	a	DET
cord-000079-533xlisc	146	26	complete	complete	ADJ
cord-000079-533xlisc	146	27	remission	remission	NOUN
cord-000079-533xlisc	146	28	on	on	ADP
cord-000079-533xlisc	146	29	mri	mri	NOUN
cord-000079-533xlisc	146	30	(	(	PUNCT
cord-000079-533xlisc	146	31	figure	figure	NOUN
cord-000079-533xlisc	146	32	6	6	NUM
cord-000079-533xlisc	146	33	)	)	PUNCT
cord-000079-533xlisc	146	34	.	.	PUNCT
cord-000079-533xlisc	147	1	one	one	NUM
cord-000079-533xlisc	147	2	animal	animal	NOUN
cord-000079-533xlisc	147	3	in	in	ADP
cord-000079-533xlisc	147	4	each	each	DET
cord-000079-533xlisc	147	5	group	group	NOUN
cord-000079-533xlisc	147	6	had	have	VERB
cord-000079-533xlisc	147	7	a	a	DET
cord-000079-533xlisc	147	8	stable	stable	ADJ
cord-000079-533xlisc	147	9	disease	disease	NOUN
cord-000079-533xlisc	147	10	until	until	ADP
cord-000079-533xlisc	147	11	the	the	DET
cord-000079-533xlisc	147	12	end	end	NOUN
cord-000079-533xlisc	147	13	of	of	ADP
cord-000079-533xlisc	147	14	gc	gc	PROPN
cord-000079-533xlisc	147	15	treatment	treatment	NOUN
cord-000079-533xlisc	147	16	.	.	PUNCT
cord-000079-533xlisc	148	1	all	all	DET
cord-000079-533xlisc	148	2	animals	animal	NOUN
cord-000079-533xlisc	148	3	in	in	ADP
cord-000079-533xlisc	148	4	the	the	DET
cord-000079-533xlisc	148	5	control	control	NOUN
cord-000079-533xlisc	148	6	groups	group	NOUN
cord-000079-533xlisc	148	7	developed	develop	VERB
cord-000079-533xlisc	148	8	large	large	ADJ
cord-000079-533xlisc	148	9	tumors	tumor	NOUN
cord-000079-533xlisc	148	10	during	during	ADP
cord-000079-533xlisc	148	11	the	the	DET
cord-000079-533xlisc	148	12	treatment	treatment	NOUN
cord-000079-533xlisc	148	13	period	period	NOUN
cord-000079-533xlisc	148	14	of	of	ADP
cord-000079-533xlisc	148	15	30	30	NUM
cord-000079-533xlisc	148	16	days	day	NOUN
cord-000079-533xlisc	148	17	(	(	PUNCT
cord-000079-533xlisc	148	18	figure	figure	NOUN
cord-000079-533xlisc	148	19	6	6	NUM
cord-000079-533xlisc	148	20	)	)	PUNCT
cord-000079-533xlisc	148	21	.	.	PUNCT
cord-000079-533xlisc	149	1	both	both	PRON
cord-000079-533xlisc	149	2	,	,	PUNCT
cord-000079-533xlisc	149	3	lcmv	lcmv	PROPN
cord-000079-533xlisc	149	4	-	-	PUNCT
cord-000079-533xlisc	149	5	and	and	CCONJ
cord-000079-533xlisc	149	6	vsv	vsv	PROPN
cord-000079-533xlisc	149	7	-	-	PUNCT
cord-000079-533xlisc	149	8	pseudotype	pseudotype	ADJ
cord-000079-533xlisc	149	9	treated	treat	VERB
cord-000079-533xlisc	149	10	animals	animal	NOUN
cord-000079-533xlisc	149	11	had	have	VERB
cord-000079-533xlisc	149	12	a	a	DET
cord-000079-533xlisc	149	13	highly	highly	ADV
cord-000079-533xlisc	149	14	significant	significant	ADJ
cord-000079-533xlisc	149	15	survival	survival	NOUN
cord-000079-533xlisc	149	16	advantage	advantage	NOUN
cord-000079-533xlisc	149	17	(	(	PUNCT
cord-000079-533xlisc	149	18	p,0.001	p,0.001	NOUN
cord-000079-533xlisc	149	19	)	)	PUNCT
cord-000079-533xlisc	149	20	compared	compare	VERB
cord-000079-533xlisc	149	21	to	to	ADP
cord-000079-533xlisc	149	22	the	the	DET
cord-000079-533xlisc	149	23	control	control	NOUN
cord-000079-533xlisc	149	24	groups	group	NOUN
cord-000079-533xlisc	149	25	(	(	PUNCT
cord-000079-533xlisc	149	26	figure	figure	NOUN
cord-000079-533xlisc	149	27	7a	7a	NUM
cord-000079-533xlisc	149	28	)	)	PUNCT
cord-000079-533xlisc	149	29	.	.	PUNCT
cord-000079-533xlisc	150	1	there	there	PRON
cord-000079-533xlisc	150	2	was	be	VERB
cord-000079-533xlisc	150	3	no	no	DET
cord-000079-533xlisc	150	4	statistically	statistically	ADV
cord-000079-533xlisc	150	5	significant	significant	ADJ
cord-000079-533xlisc	150	6	difference	difference	NOUN
cord-000079-533xlisc	150	7	in	in	ADP
cord-000079-533xlisc	150	8	survival	survival	NOUN
cord-000079-533xlisc	150	9	between	between	ADP
cord-000079-533xlisc	150	10	the	the	DET
cord-000079-533xlisc	150	11	two	two	NUM
cord-000079-533xlisc	150	12	treatment	treatment	NOUN
cord-000079-533xlisc	150	13	groups	group	NOUN
cord-000079-533xlisc	150	14	.	.	PUNCT
cord-000079-533xlisc	151	1	upon	upon	SCONJ
cord-000079-533xlisc	151	2	cessation	cessation	NOUN
cord-000079-533xlisc	151	3	of	of	ADP
cord-000079-533xlisc	151	4	prodrug	prodrug	PROPN
cord-000079-533xlisc	151	5	administration	administration	NOUN
cord-000079-533xlisc	151	6	,	,	PUNCT
cord-000079-533xlisc	151	7	all	all	DET
cord-000079-533xlisc	151	8	animals	animal	NOUN
cord-000079-533xlisc	151	9	developed	develop	VERB
cord-000079-533xlisc	151	10	recurrent	recurrent	ADJ
cord-000079-533xlisc	151	11	tumors	tumor	NOUN
cord-000079-533xlisc	151	12	,	,	PUNCT
cord-000079-533xlisc	151	13	which	which	PRON
cord-000079-533xlisc	151	14	could	could	AUX
cord-000079-533xlisc	151	15	be	be	AUX
cord-000079-533xlisc	151	16	classified	classify	VERB
cord-000079-533xlisc	151	17	into	into	ADP
cord-000079-533xlisc	151	18	three	three	NUM
cord-000079-533xlisc	151	19	different	different	ADJ
cord-000079-533xlisc	151	20	groups	group	NOUN
cord-000079-533xlisc	151	21	(	(	PUNCT
cord-000079-533xlisc	151	22	figure	figure	VERB
cord-000079-533xlisc	151	23	7b	7b	NUM
cord-000079-533xlisc	151	24	-	-	PUNCT
cord-000079-533xlisc	151	25	e	e	NOUN
cord-000079-533xlisc	151	26	,	,	PUNCT
cord-000079-533xlisc	151	27	table	table	NOUN
cord-000079-533xlisc	151	28	2	2	NUM
cord-000079-533xlisc	151	29	)	)	PUNCT
cord-000079-533xlisc	151	30	.	.	PUNCT
cord-000079-533xlisc	152	1	the	the	DET
cord-000079-533xlisc	152	2	animals	animal	NOUN
cord-000079-533xlisc	152	3	showed	show	VERB
cord-000079-533xlisc	152	4	either	either	PRON
cord-000079-533xlisc	152	5	1	1	NUM
cord-000079-533xlisc	152	6	)	)	PUNCT
cord-000079-533xlisc	152	7	local	local	ADJ
cord-000079-533xlisc	152	8	recurrences	recurrence	NOUN
cord-000079-533xlisc	152	9	or	or	CCONJ
cord-000079-533xlisc	152	10	2	2	NUM
cord-000079-533xlisc	152	11	)	)	PUNCT
cord-000079-533xlisc	152	12	local	local	ADJ
cord-000079-533xlisc	152	13	and/or	and/or	CCONJ
cord-000079-533xlisc	152	14	contralateral	contralateral	ADJ
cord-000079-533xlisc	152	15	recurrences	recurrence	NOUN
cord-000079-533xlisc	152	16	or	or	CCONJ
cord-000079-533xlisc	152	17	3	3	NUM
cord-000079-533xlisc	152	18	)	)	PUNCT
cord-000079-533xlisc	152	19	recurrences	recurrence	NOUN
cord-000079-533xlisc	152	20	in	in	ADP
cord-000079-533xlisc	152	21	other	other	ADJ
cord-000079-533xlisc	152	22	distant	distant	ADJ
cord-000079-533xlisc	152	23	brain	brain	NOUN
cord-000079-533xlisc	152	24	areas	area	NOUN
cord-000079-533xlisc	152	25	.	.	PUNCT
cord-000079-533xlisc	153	1	there	there	PRON
cord-000079-533xlisc	153	2	was	be	VERB
cord-000079-533xlisc	153	3	no	no	DET
cord-000079-533xlisc	153	4	clear	clear	ADJ
cord-000079-533xlisc	153	5	difference	difference	NOUN
cord-000079-533xlisc	153	6	in	in	ADP
cord-000079-533xlisc	153	7	the	the	DET
cord-000079-533xlisc	153	8	recurrence	recurrence	NOUN
cord-000079-533xlisc	153	9	pattern	pattern	NOUN
cord-000079-533xlisc	153	10	between	between	ADP
cord-000079-533xlisc	153	11	the	the	DET
cord-000079-533xlisc	153	12	two	two	NUM
cord-000079-533xlisc	153	13	vector	vector	NOUN
cord-000079-533xlisc	153	14	types	type	NOUN
cord-000079-533xlisc	153	15	,	,	PUNCT
cord-000079-533xlisc	153	16	but	but	CCONJ
cord-000079-533xlisc	153	17	lcmv	lcmv	PROPN
cord-000079-533xlisc	153	18	-	-	PUNCT
cord-000079-533xlisc	153	19	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	153	20	vector	vector	NOUN
cord-000079-533xlisc	153	21	-	-	PUNCT
cord-000079-533xlisc	153	22	treated	treat	VERB
cord-000079-533xlisc	153	23	animals	animal	NOUN
cord-000079-533xlisc	153	24	had	have	VERB
cord-000079-533xlisc	153	25	more	more	ADJ
cord-000079-533xlisc	153	26	contralateral	contralateral	ADJ
cord-000079-533xlisc	153	27	recurrences	recurrence	NOUN
cord-000079-533xlisc	153	28	,	,	PUNCT
cord-000079-533xlisc	153	29	whereas	whereas	SCONJ
cord-000079-533xlisc	153	30	vsv	vsv	PROPN
cord-000079-533xlisc	153	31	-	-	NOUN
cord-000079-533xlisc	153	32	g	g	NOUN
cord-000079-533xlisc	153	33	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	153	34	vector	vector	NOUN
cord-000079-533xlisc	153	35	-	-	PUNCT
cord-000079-533xlisc	153	36	treated	treat	VERB
cord-000079-533xlisc	153	37	animals	animal	NOUN
cord-000079-533xlisc	153	38	had	have	VERB
cord-000079-533xlisc	153	39	more	more	ADJ
cord-000079-533xlisc	153	40	local	local	ADJ
cord-000079-533xlisc	153	41	recurrences	recurrence	NOUN
cord-000079-533xlisc	153	42	(	(	PUNCT
cord-000079-533xlisc	153	43	figure	figure	NOUN
cord-000079-533xlisc	153	44	7b	7b	NUM
cord-000079-533xlisc	153	45	-e	-e	NOUN
cord-000079-533xlisc	153	46	,	,	PUNCT
cord-000079-533xlisc	153	47	table	table	NOUN
cord-000079-533xlisc	153	48	2	2	NUM
cord-000079-533xlisc	153	49	)	)	PUNCT
cord-000079-533xlisc	153	50	.	.	PUNCT
cord-000079-533xlisc	154	1	histopathological	histopathological	ADJ
cord-000079-533xlisc	154	2	and	and	CCONJ
cord-000079-533xlisc	154	3	confocal	confocal	ADJ
cord-000079-533xlisc	154	4	microscopic	microscopic	ADJ
cord-000079-533xlisc	154	5	analysis	analysis	NOUN
cord-000079-533xlisc	154	6	of	of	ADP
cord-000079-533xlisc	154	7	the	the	DET
cord-000079-533xlisc	154	8	lesions	lesion	NOUN
cord-000079-533xlisc	154	9	revealed	reveal	VERB
cord-000079-533xlisc	154	10	gfp	gfp	NOUN
cord-000079-533xlisc	154	11	-	-	PUNCT
cord-000079-533xlisc	154	12	positive	positive	ADJ
cord-000079-533xlisc	154	13	cells	cell	NOUN
cord-000079-533xlisc	154	14	in	in	ADP
cord-000079-533xlisc	154	15	all	all	DET
cord-000079-533xlisc	154	16	recurrent	recurrent	ADJ
cord-000079-533xlisc	154	17	tumors	tumor	NOUN
cord-000079-533xlisc	154	18	demonstrating	demonstrate	VERB
cord-000079-533xlisc	154	19	that	that	SCONJ
cord-000079-533xlisc	154	20	not	not	PART
cord-000079-533xlisc	154	21	all	all	DET
cord-000079-533xlisc	154	22	transduced	transduced	ADJ
cord-000079-533xlisc	154	23	glioma	glioma	NOUN
cord-000079-533xlisc	154	24	cells	cell	NOUN
cord-000079-533xlisc	154	25	were	be	AUX
cord-000079-533xlisc	154	26	killed	kill	VERB
cord-000079-533xlisc	154	27	by	by	ADP
cord-000079-533xlisc	154	28	ganciclovir	ganciclovir	PROPN
cord-000079-533xlisc	154	29	treatment	treatment	NOUN
cord-000079-533xlisc	154	30	(	(	PUNCT
cord-000079-533xlisc	154	31	figure	figure	NOUN
cord-000079-533xlisc	154	32	7f	7f	PROPN
cord-000079-533xlisc	154	33	-	-	PUNCT
cord-000079-533xlisc	154	34	m	m	NOUN
cord-000079-533xlisc	154	35	)	)	PUNCT
cord-000079-533xlisc	154	36	.	.	PUNCT
cord-000079-533xlisc	155	1	in	in	ADP
cord-000079-533xlisc	155	2	vsv	vsv	PROPN
cord-000079-533xlisc	155	3	-	-	PROPN
cord-000079-533xlisc	155	4	g	g	NOUN
cord-000079-533xlisc	155	5	pseudotype	pseudotype	NOUN
cord-000079-533xlisc	155	6	-	-	PUNCT
cord-000079-533xlisc	155	7	treated	treat	VERB
cord-000079-533xlisc	155	8	animals	animal	NOUN
cord-000079-533xlisc	155	9	,	,	PUNCT
cord-000079-533xlisc	155	10	the	the	DET
cord-000079-533xlisc	155	11	gfp	gfp	NOUN
cord-000079-533xlisc	155	12	-	-	PUNCT
cord-000079-533xlisc	155	13	positive	positive	ADJ
cord-000079-533xlisc	155	14	surviving	surviving	NOUN
cord-000079-533xlisc	155	15	cells	cell	NOUN
cord-000079-533xlisc	155	16	were	be	AUX
cord-000079-533xlisc	155	17	found	find	VERB
cord-000079-533xlisc	155	18	in	in	ADP
cord-000079-533xlisc	155	19	invasive	invasive	ADJ
cord-000079-533xlisc	155	20	areas	area	NOUN
cord-000079-533xlisc	155	21	(	(	PUNCT
cord-000079-533xlisc	155	22	figure	figure	NOUN
cord-000079-533xlisc	155	23	7f	7f	NOUN
cord-000079-533xlisc	155	24	,	,	PUNCT
cord-000079-533xlisc	155	25	g	g	NOUN
cord-000079-533xlisc	155	26	)	)	PUNCT
cord-000079-533xlisc	155	27	,	,	PUNCT
cord-000079-533xlisc	155	28	the	the	DET
cord-000079-533xlisc	155	29	corpus	corpus	PROPN
cord-000079-533xlisc	155	30	callosum	callosum	PROPN
cord-000079-533xlisc	155	31	region	region	NOUN
cord-000079-533xlisc	155	32	(	(	PUNCT
cord-000079-533xlisc	155	33	figure	figure	NOUN
cord-000079-533xlisc	155	34	7h	7h	PROPN
cord-000079-533xlisc	155	35	)	)	PUNCT
cord-000079-533xlisc	155	36	and	and	CCONJ
cord-000079-533xlisc	155	37	also	also	ADV
cord-000079-533xlisc	155	38	in	in	ADP
cord-000079-533xlisc	155	39	some	some	DET
cord-000079-533xlisc	155	40	regions	region	NOUN
cord-000079-533xlisc	155	41	of	of	ADP
cord-000079-533xlisc	155	42	distant	distant	ADJ
cord-000079-533xlisc	155	43	recurrences	recurrence	NOUN
cord-000079-533xlisc	155	44	.	.	PUNCT
cord-000079-533xlisc	156	1	one	one	NUM
cord-000079-533xlisc	156	2	animal	animal	NOUN
cord-000079-533xlisc	156	3	also	also	ADV
cord-000079-533xlisc	156	4	showed	show	VERB
cord-000079-533xlisc	156	5	a	a	DET
cord-000079-533xlisc	156	6	focus	focus	NOUN
cord-000079-533xlisc	156	7	of	of	ADP
cord-000079-533xlisc	156	8	transduced	transduced	ADJ
cord-000079-533xlisc	156	9	normal	normal	ADJ
cord-000079-533xlisc	156	10	brain	brain	NOUN
cord-000079-533xlisc	156	11	cells	cell	NOUN
cord-000079-533xlisc	156	12	at	at	ADP
cord-000079-533xlisc	156	13	the	the	DET
cord-000079-533xlisc	156	14	tumor	tumor	NOUN
cord-000079-533xlisc	156	15	border	border	NOUN
cord-000079-533xlisc	156	16	that	that	PRON
cord-000079-533xlisc	156	17	survived	survive	VERB
cord-000079-533xlisc	156	18	gc	gc	PROPN
cord-000079-533xlisc	156	19	treatment	treatment	NOUN
cord-000079-533xlisc	156	20	(	(	PUNCT
cord-000079-533xlisc	156	21	figure	figure	NOUN
cord-000079-533xlisc	156	22	7i	7i	PROPN
cord-000079-533xlisc	156	23	)	)	PUNCT
cord-000079-533xlisc	156	24	.	.	PUNCT
cord-000079-533xlisc	157	1	in	in	ADP
cord-000079-533xlisc	157	2	the	the	DET
cord-000079-533xlisc	157	3	lcmv	lcmv	PROPN
cord-000079-533xlisc	157	4	group	group	PROPN
cord-000079-533xlisc	157	5	,	,	PUNCT
cord-000079-533xlisc	157	6	most	most	ADJ
cord-000079-533xlisc	157	7	gfp	gfp	NOUN
cord-000079-533xlisc	157	8	-	-	PUNCT
cord-000079-533xlisc	157	9	positive	positive	ADJ
cord-000079-533xlisc	157	10	cells	cell	NOUN
cord-000079-533xlisc	157	11	were	be	AUX
cord-000079-533xlisc	157	12	found	find	VERB
cord-000079-533xlisc	157	13	in	in	ADP
cord-000079-533xlisc	157	14	the	the	DET
cord-000079-533xlisc	157	15	ipsilateral	ipsilateral	ADJ
cord-000079-533xlisc	157	16	hemisphere	hemisphere	NOUN
cord-000079-533xlisc	157	17	,	,	PUNCT
cord-000079-533xlisc	157	18	in	in	ADP
cord-000079-533xlisc	157	19	solid	solid	ADJ
cord-000079-533xlisc	157	20	and	and	CCONJ
cord-000079-533xlisc	157	21	invasive	invasive	ADJ
cord-000079-533xlisc	157	22	tumor	tumor	NOUN
cord-000079-533xlisc	157	23	areas	area	NOUN
cord-000079-533xlisc	157	24	(	(	PUNCT
cord-000079-533xlisc	157	25	figure	figure	VERB
cord-000079-533xlisc	157	26	7j	7j	NUM
cord-000079-533xlisc	157	27	,	,	PUNCT
cord-000079-533xlisc	157	28	k	k	PROPN
cord-000079-533xlisc	157	29	,	,	PUNCT
cord-000079-533xlisc	157	30	l	l	NOUN
cord-000079-533xlisc	157	31	)	)	PUNCT
cord-000079-533xlisc	157	32	,	,	PUNCT
cord-000079-533xlisc	157	33	with	with	ADP
cord-000079-533xlisc	157	34	only	only	ADV
cord-000079-533xlisc	157	35	a	a	DET
cord-000079-533xlisc	157	36	few	few	ADJ
cord-000079-533xlisc	157	37	cells	cell	NOUN
cord-000079-533xlisc	157	38	seen	see	VERB
cord-000079-533xlisc	157	39	in	in	ADP
cord-000079-533xlisc	157	40	the	the	DET
cord-000079-533xlisc	157	41	contralateral	contralateral	ADJ
cord-000079-533xlisc	157	42	hemisphere	hemisphere	NOUN
cord-000079-533xlisc	157	43	(	(	PUNCT
cord-000079-533xlisc	157	44	figure	figure	VERB
cord-000079-533xlisc	157	45	7	7	NUM
cord-000079-533xlisc	157	46	m	m	NUM
cord-000079-533xlisc	157	47	)	)	PUNCT
cord-000079-533xlisc	157	48	.	.	PUNCT
cord-000079-533xlisc	158	1	future	future	ADJ
cord-000079-533xlisc	158	2	success	success	NOUN
cord-000079-533xlisc	158	3	of	of	ADP
cord-000079-533xlisc	158	4	glioma	glioma	NOUN
cord-000079-533xlisc	158	5	gene	gene	NOUN
cord-000079-533xlisc	158	6	therapy	therapy	NOUN
cord-000079-533xlisc	158	7	will	will	AUX
cord-000079-533xlisc	158	8	depend	depend	VERB
cord-000079-533xlisc	158	9	on	on	ADP
cord-000079-533xlisc	158	10	more	more	ADV
cord-000079-533xlisc	158	11	potent	potent	ADJ
cord-000079-533xlisc	158	12	vector	vector	NOUN
cord-000079-533xlisc	158	13	systems	system	NOUN
cord-000079-533xlisc	158	14	that	that	PRON
cord-000079-533xlisc	158	15	show	show	VERB
cord-000079-533xlisc	158	16	higher	high	ADJ
cord-000079-533xlisc	158	17	transduction	transduction	NOUN
cord-000079-533xlisc	158	18	efficiency	efficiency	NOUN
cord-000079-533xlisc	158	19	than	than	ADP
cord-000079-533xlisc	158	20	the	the	DET
cord-000079-533xlisc	158	21	systems	system	NOUN
cord-000079-533xlisc	158	22	that	that	PRON
cord-000079-533xlisc	158	23	are	be	AUX
cord-000079-533xlisc	158	24	available	available	ADJ
cord-000079-533xlisc	158	25	today	today	NOUN
cord-000079-533xlisc	158	26	.	.	PUNCT
cord-000079-533xlisc	159	1	in	in	ADP
cord-000079-533xlisc	159	2	addition	addition	NOUN
cord-000079-533xlisc	159	3	,	,	PUNCT
cord-000079-533xlisc	159	4	the	the	DET
cord-000079-533xlisc	159	5	application	application	NOUN
cord-000079-533xlisc	159	6	of	of	ADP
cord-000079-533xlisc	159	7	representative	representative	ADJ
cord-000079-533xlisc	159	8	animal	animal	NOUN
cord-000079-533xlisc	159	9	models	model	NOUN
cord-000079-533xlisc	159	10	that	that	PRON
cord-000079-533xlisc	159	11	recapitulate	recapitulate	VERB
cord-000079-533xlisc	159	12	both	both	PRON
cord-000079-533xlisc	159	13	,	,	PUNCT
cord-000079-533xlisc	159	14	the	the	DET
cord-000079-533xlisc	159	15	invasive	invasive	ADJ
cord-000079-533xlisc	159	16	and	and	CCONJ
cord-000079-533xlisc	159	17	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	159	18	features	feature	NOUN
cord-000079-533xlisc	159	19	of	of	ADP
cord-000079-533xlisc	159	20	patient	patient	ADJ
cord-000079-533xlisc	159	21	tumors	tumor	NOUN
cord-000079-533xlisc	159	22	,	,	PUNCT
cord-000079-533xlisc	159	23	is	be	AUX
cord-000079-533xlisc	159	24	vital	vital	ADJ
cord-000079-533xlisc	159	25	in	in	ADP
cord-000079-533xlisc	159	26	order	order	NOUN
cord-000079-533xlisc	159	27	to	to	PART
cord-000079-533xlisc	159	28	minimize	minimize	VERB
cord-000079-533xlisc	159	29	the	the	DET
cord-000079-533xlisc	159	30	huge	huge	ADJ
cord-000079-533xlisc	159	31	discrepancies	discrepancy	NOUN
cord-000079-533xlisc	159	32	between	between	ADP
cord-000079-533xlisc	159	33	the	the	DET
cord-000079-533xlisc	159	34	experimental	experimental	ADJ
cord-000079-533xlisc	159	35	results	result	NOUN
cord-000079-533xlisc	159	36	and	and	CCONJ
cord-000079-533xlisc	159	37	clinical	clinical	ADJ
cord-000079-533xlisc	159	38	outcomes	outcome	NOUN
cord-000079-533xlisc	159	39	previously	previously	ADV
cord-000079-533xlisc	159	40	observed	observe	VERB
cord-000079-533xlisc	159	41	for	for	ADP
cord-000079-533xlisc	159	42	gene	gene	NOUN
cord-000079-533xlisc	159	43	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	159	44	strategies	strategy	NOUN
cord-000079-533xlisc	159	45	for	for	ADP
cord-000079-533xlisc	159	46	brain	brain	NOUN
cord-000079-533xlisc	159	47	cancer	cancer	NOUN
cord-000079-533xlisc	159	48	.	.	PUNCT
cord-000079-533xlisc	160	1	to	to	ADP
cord-000079-533xlisc	160	2	this	this	DET
cord-000079-533xlisc	160	3	end	end	NOUN
cord-000079-533xlisc	160	4	,	,	PUNCT
cord-000079-533xlisc	160	5	we	we	PRON
cord-000079-533xlisc	160	6	applied	apply	VERB
cord-000079-533xlisc	160	7	one	one	NUM
cord-000079-533xlisc	160	8	of	of	ADP
cord-000079-533xlisc	160	9	the	the	DET
cord-000079-533xlisc	160	10	most	most	ADV
cord-000079-533xlisc	160	11	clinically	clinically	ADV
cord-000079-533xlisc	160	12	relevant	relevant	ADJ
cord-000079-533xlisc	160	13	animal	animal	NOUN
cord-000079-533xlisc	160	14	models	model	NOUN
cord-000079-533xlisc	160	15	for	for	ADP
cord-000079-533xlisc	160	16	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	160	17	known	know	VERB
cord-000079-533xlisc	160	18	.	.	PUNCT
cord-000079-533xlisc	161	1	this	this	DET
cord-000079-533xlisc	161	2	model	model	NOUN
cord-000079-533xlisc	161	3	was	be	AUX
cord-000079-533xlisc	161	4	established	establish	VERB
cord-000079-533xlisc	161	5	several	several	ADJ
cord-000079-533xlisc	161	6	years	year	NOUN
cord-000079-533xlisc	161	7	ago	ago	ADV
cord-000079-533xlisc	161	8	[	[	X
cord-000079-533xlisc	161	9	20	20	NUM
cord-000079-533xlisc	161	10	]	]	PUNCT
cord-000079-533xlisc	161	11	and	and	CCONJ
cord-000079-533xlisc	161	12	its	its	PRON
cord-000079-533xlisc	161	13	growth	growth	NOUN
cord-000079-533xlisc	161	14	pattern	pattern	NOUN
cord-000079-533xlisc	161	15	as	as	ADV
cord-000079-533xlisc	161	16	well	well	ADV
cord-000079-533xlisc	161	17	as	as	ADP
cord-000079-533xlisc	161	18	geno	geno	NOUN
cord-000079-533xlisc	161	19	-	-	PUNCT
cord-000079-533xlisc	161	20	and	and	CCONJ
cord-000079-533xlisc	161	21	phenotypic	phenotypic	ADJ
cord-000079-533xlisc	161	22	similarity	similarity	NOUN
cord-000079-533xlisc	161	23	to	to	PART
cord-000079-533xlisc	161	24	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	161	25	in	in	ADP
cord-000079-533xlisc	161	26	patients	patient	NOUN
cord-000079-533xlisc	161	27	has	have	AUX
cord-000079-533xlisc	161	28	been	be	AUX
cord-000079-533xlisc	161	29	extensively	extensively	ADV
cord-000079-533xlisc	161	30	characterized	characterize	VERB
cord-000079-533xlisc	161	31	[	[	X
cord-000079-533xlisc	161	32	3	3	NUM
cord-000079-533xlisc	161	33	]	]	PUNCT
cord-000079-533xlisc	161	34	.	.	PUNCT
cord-000079-533xlisc	162	1	a	a	DET
cord-000079-533xlisc	162	2	striking	striking	ADJ
cord-000079-533xlisc	162	3	difference	difference	NOUN
cord-000079-533xlisc	162	4	of	of	ADP
cord-000079-533xlisc	162	5	our	our	PRON
cord-000079-533xlisc	162	6	model	model	NOUN
cord-000079-533xlisc	162	7	compared	compare	VERB
cord-000079-533xlisc	162	8	to	to	ADP
cord-000079-533xlisc	162	9	other	other	ADJ
cord-000079-533xlisc	162	10	cell	cell	NOUN
cord-000079-533xlisc	162	11	-	-	PUNCT
cord-000079-533xlisc	162	12	line	line	NOUN
cord-000079-533xlisc	162	13	based	base	VERB
cord-000079-533xlisc	162	14	models	model	NOUN
cord-000079-533xlisc	162	15	is	be	AUX
cord-000079-533xlisc	162	16	the	the	DET
cord-000079-533xlisc	162	17	highly	highly	ADV
cord-000079-533xlisc	162	18	invasive	invasive	ADJ
cord-000079-533xlisc	162	19	behaviour	behaviour	NOUN
cord-000079-533xlisc	162	20	of	of	ADP
cord-000079-533xlisc	162	21	the	the	DET
cord-000079-533xlisc	162	22	lesions	lesion	NOUN
cord-000079-533xlisc	162	23	,	,	PUNCT
cord-000079-533xlisc	162	24	similar	similar	ADJ
cord-000079-533xlisc	162	25	to	to	ADP
cord-000079-533xlisc	162	26	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	162	27	in	in	ADP
cord-000079-533xlisc	162	28	patients	patient	NOUN
cord-000079-533xlisc	162	29	.	.	PUNCT
cord-000079-533xlisc	163	1	our	our	PRON
cord-000079-533xlisc	163	2	model	model	NOUN
cord-000079-533xlisc	163	3	is	be	AUX
cord-000079-533xlisc	163	4	based	base	VERB
cord-000079-533xlisc	163	5	on	on	ADP
cord-000079-533xlisc	163	6	spheroids	spheroid	NOUN
cord-000079-533xlisc	163	7	derived	derive	VERB
cord-000079-533xlisc	163	8	from	from	ADP
cord-000079-533xlisc	163	9	patient	patient	ADJ
cord-000079-533xlisc	163	10	biopsies	biopsy	NOUN
cord-000079-533xlisc	163	11	that	that	PRON
cord-000079-533xlisc	163	12	are	be	AUX
cord-000079-533xlisc	163	13	passaged	passage	VERB
cord-000079-533xlisc	163	14	serially	serially	ADV
cord-000079-533xlisc	163	15	in	in	ADP
cord-000079-533xlisc	163	16	the	the	DET
cord-000079-533xlisc	163	17	brains	brain	NOUN
cord-000079-533xlisc	163	18	of	of	ADP
cord-000079-533xlisc	163	19	nude	nude	ADJ
cord-000079-533xlisc	163	20	rats	rat	NOUN
cord-000079-533xlisc	163	21	.	.	PUNCT
cord-000079-533xlisc	164	1	first	first	ADJ
cord-000079-533xlisc	164	2	generation	generation	NOUN
cord-000079-533xlisc	164	3	tumors	tumor	NOUN
cord-000079-533xlisc	164	4	are	be	AUX
cord-000079-533xlisc	164	5	highly	highly	ADV
cord-000079-533xlisc	164	6	invasive	invasive	ADJ
cord-000079-533xlisc	164	7	and	and	CCONJ
cord-000079-533xlisc	164	8	grow	grow	VERB
cord-000079-533xlisc	164	9	without	without	ADP
cord-000079-533xlisc	164	10	signs	sign	NOUN
cord-000079-533xlisc	164	11	of	of	ADP
cord-000079-533xlisc	164	12	angiogenesis	angiogenesis	NOUN
cord-000079-533xlisc	164	13	.	.	PUNCT
cord-000079-533xlisc	165	1	late	late	ADJ
cord-000079-533xlisc	165	2	generation	generation	NOUN
cord-000079-533xlisc	165	3	tumors	tumor	NOUN
cord-000079-533xlisc	165	4	show	show	VERB
cord-000079-533xlisc	165	5	an	an	DET
cord-000079-533xlisc	165	6	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	165	7	phenotype	phenotype	NOUN
cord-000079-533xlisc	165	8	,	,	PUNCT
cord-000079-533xlisc	165	9	but	but	CCONJ
cord-000079-533xlisc	165	10	are	be	AUX
cord-000079-533xlisc	165	11	still	still	ADV
cord-000079-533xlisc	165	12	invasive	invasive	ADJ
cord-000079-533xlisc	165	13	.	.	PUNCT
cord-000079-533xlisc	166	1	our	our	PRON
cord-000079-533xlisc	166	2	in	in	X
cord-000079-533xlisc	166	3	vitro	vitro	X
cord-000079-533xlisc	166	4	experiments	experiment	NOUN
cord-000079-533xlisc	166	5	revealed	reveal	VERB
cord-000079-533xlisc	166	6	that	that	SCONJ
cord-000079-533xlisc	166	7	both	both	DET
cord-000079-533xlisc	166	8	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	166	9	vectors	vector	NOUN
cord-000079-533xlisc	166	10	transduced	transduce	VERB
cord-000079-533xlisc	166	11	spheroids	spheroid	NOUN
cord-000079-533xlisc	166	12	derived	derive	VERB
cord-000079-533xlisc	166	13	from	from	ADP
cord-000079-533xlisc	166	14	both	both	CCONJ
cord-000079-533xlisc	166	15	low	low	ADJ
cord-000079-533xlisc	166	16	and	and	CCONJ
cord-000079-533xlisc	166	17	high	high	ADJ
cord-000079-533xlisc	166	18	generation	generation	NOUN
cord-000079-533xlisc	166	19	tumors	tumor	NOUN
cord-000079-533xlisc	166	20	very	very	ADV
cord-000079-533xlisc	166	21	efficiently	efficiently	ADV
cord-000079-533xlisc	166	22	.	.	PUNCT
cord-000079-533xlisc	167	1	in	in	ADP
cord-000079-533xlisc	167	2	contrast	contrast	NOUN
cord-000079-533xlisc	167	3	,	,	PUNCT
cord-000079-533xlisc	167	4	retroviral	retroviral	ADJ
cord-000079-533xlisc	167	5	vectors	vector	NOUN
cord-000079-533xlisc	167	6	transduced	transduce	VERB
cord-000079-533xlisc	167	7	only	only	ADV
cord-000079-533xlisc	167	8	high	high	ADJ
cord-000079-533xlisc	167	9	generation	generation	NOUN
cord-000079-533xlisc	167	10	spheroids	spheroid	NOUN
cord-000079-533xlisc	167	11	and	and	CCONJ
cord-000079-533xlisc	167	12	displayed	display	VERB
cord-000079-533xlisc	167	13	a	a	DET
cord-000079-533xlisc	167	14	much	much	ADV
cord-000079-533xlisc	167	15	lower	low	ADJ
cord-000079-533xlisc	167	16	efficiency	efficiency	NOUN
cord-000079-533xlisc	167	17	of	of	ADP
cord-000079-533xlisc	167	18	gene	gene	NOUN
cord-000079-533xlisc	167	19	transfer	transfer	NOUN
cord-000079-533xlisc	167	20	than	than	ADP
cord-000079-533xlisc	167	21	both	both	DET
cord-000079-533xlisc	167	22	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	167	23	vectors	vector	NOUN
cord-000079-533xlisc	167	24	.	.	PUNCT
cord-000079-533xlisc	168	1	this	this	DET
cord-000079-533xlisc	168	2	difference	difference	NOUN
cord-000079-533xlisc	168	3	can	can	AUX
cord-000079-533xlisc	168	4	only	only	ADV
cord-000079-533xlisc	168	5	be	be	AUX
cord-000079-533xlisc	168	6	attributed	attribute	VERB
cord-000079-533xlisc	168	7	to	to	ADP
cord-000079-533xlisc	168	8	the	the	DET
cord-000079-533xlisc	168	9	vector	vector	NOUN
cord-000079-533xlisc	168	10	backbone	backbone	NOUN
cord-000079-533xlisc	168	11	,	,	PUNCT
cord-000079-533xlisc	168	12	as	as	SCONJ
cord-000079-533xlisc	168	13	the	the	DET
cord-000079-533xlisc	168	14	glycoprotein	glycoprotein	NOUN
cord-000079-533xlisc	168	15	which	which	PRON
cord-000079-533xlisc	168	16	is	be	AUX
cord-000079-533xlisc	168	17	responsible	responsible	ADJ
cord-000079-533xlisc	168	18	for	for	ADP
cord-000079-533xlisc	168	19	virus	virus	NOUN
cord-000079-533xlisc	168	20	entry	entry	NOUN
cord-000079-533xlisc	168	21	into	into	ADP
cord-000079-533xlisc	168	22	the	the	DET
cord-000079-533xlisc	168	23	cell	cell	NOUN
cord-000079-533xlisc	168	24	was	be	AUX
cord-000079-533xlisc	168	25	the	the	DET
cord-000079-533xlisc	168	26	same	same	ADJ
cord-000079-533xlisc	168	27	for	for	ADP
cord-000079-533xlisc	168	28	the	the	DET
cord-000079-533xlisc	168	29	retroviral	retroviral	ADJ
cord-000079-533xlisc	168	30	and	and	CCONJ
cord-000079-533xlisc	168	31	one	one	NUM
cord-000079-533xlisc	168	32	of	of	ADP
cord-000079-533xlisc	168	33	the	the	DET
cord-000079-533xlisc	168	34	lentivral	lentivral	ADJ
cord-000079-533xlisc	168	35	vectors	vector	NOUN
cord-000079-533xlisc	168	36	applied	apply	VERB
cord-000079-533xlisc	168	37	(	(	PUNCT
cord-000079-533xlisc	168	38	lcmv	lcmv	PROPN
cord-000079-533xlisc	168	39	-	-	PUNCT
cord-000079-533xlisc	168	40	gp	gp	PROPN
cord-000079-533xlisc	168	41	)	)	PUNCT
cord-000079-533xlisc	168	42	.	.	PUNCT
cord-000079-533xlisc	169	1	the	the	DET
cord-000079-533xlisc	169	2	most	most	ADV
cord-000079-533xlisc	169	3	important	important	ADJ
cord-000079-533xlisc	169	4	feature	feature	NOUN
cord-000079-533xlisc	169	5	that	that	PRON
cord-000079-533xlisc	169	6	distinguishes	distinguish	VERB
cord-000079-533xlisc	169	7	lentiviral	lentiviral	NOUN
cord-000079-533xlisc	169	8	from	from	ADP
cord-000079-533xlisc	169	9	retroviral	retroviral	ADJ
cord-000079-533xlisc	169	10	vectors	vector	NOUN
cord-000079-533xlisc	169	11	is	be	AUX
cord-000079-533xlisc	169	12	their	their	PRON
cord-000079-533xlisc	169	13	ability	ability	NOUN
cord-000079-533xlisc	169	14	to	to	PART
cord-000079-533xlisc	169	15	infect	infect	VERB
cord-000079-533xlisc	169	16	non	non	ADJ
cord-000079-533xlisc	169	17	-	-	ADJ
cord-000079-533xlisc	169	18	dividing	dividing	ADJ
cord-000079-533xlisc	169	19	cells	cell	NOUN
cord-000079-533xlisc	169	20	.	.	PUNCT
cord-000079-533xlisc	170	1	it	it	PRON
cord-000079-533xlisc	170	2	is	be	AUX
cord-000079-533xlisc	170	3	known	know	VERB
cord-000079-533xlisc	170	4	that	that	SCONJ
cord-000079-533xlisc	170	5	glioma	glioma	NOUN
cord-000079-533xlisc	170	6	spheroids	spheroid	NOUN
cord-000079-533xlisc	170	7	,	,	PUNCT
cord-000079-533xlisc	170	8	especially	especially	ADV
cord-000079-533xlisc	170	9	primary	primary	ADJ
cord-000079-533xlisc	170	10	biopsy	biopsy	ADJ
cord-000079-533xlisc	170	11	spheroids	spheroid	NOUN
cord-000079-533xlisc	170	12	,	,	PUNCT
cord-000079-533xlisc	170	13	contain	contain	VERB
cord-000079-533xlisc	170	14	a	a	DET
cord-000079-533xlisc	170	15	significant	significant	ADJ
cord-000079-533xlisc	170	16	fraction	fraction	NOUN
cord-000079-533xlisc	170	17	of	of	ADP
cord-000079-533xlisc	170	18	non	non	ADJ
cord-000079-533xlisc	170	19	-	-	ADJ
cord-000079-533xlisc	170	20	dividing	dividing	ADJ
cord-000079-533xlisc	170	21	cells	cell	NOUN
cord-000079-533xlisc	170	22	,	,	PUNCT
cord-000079-533xlisc	170	23	which	which	PRON
cord-000079-533xlisc	170	24	can	can	AUX
cord-000079-533xlisc	170	25	not	not	PART
cord-000079-533xlisc	170	26	be	be	AUX
cord-000079-533xlisc	170	27	transduced	transduce	VERB
cord-000079-533xlisc	170	28	by	by	ADP
cord-000079-533xlisc	170	29	retroviral	retroviral	ADJ
cord-000079-533xlisc	170	30	vectors	vector	NOUN
cord-000079-533xlisc	170	31	.	.	PUNCT
cord-000079-533xlisc	171	1	it	it	PRON
cord-000079-533xlisc	171	2	has	have	AUX
cord-000079-533xlisc	171	3	previously	previously	ADV
cord-000079-533xlisc	171	4	been	be	AUX
cord-000079-533xlisc	171	5	shown	show	VERB
cord-000079-533xlisc	171	6	that	that	SCONJ
cord-000079-533xlisc	171	7	the	the	DET
cord-000079-533xlisc	171	8	cultured	cultured	ADJ
cord-000079-533xlisc	171	9	biopsy	biopsy	PROPN
cord-000079-533xlisc	171	10	spheroids	spheroid	NOUN
cord-000079-533xlisc	171	11	show	show	VERB
cord-000079-533xlisc	171	12	a	a	DET
cord-000079-533xlisc	171	13	similar	similar	ADJ
cord-000079-533xlisc	171	14	cell	cell	NOUN
cord-000079-533xlisc	171	15	proliferation	proliferation	NOUN
cord-000079-533xlisc	171	16	as	as	SCONJ
cord-000079-533xlisc	171	17	seen	see	VERB
cord-000079-533xlisc	171	18	in	in	ADP
cord-000079-533xlisc	171	19	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	171	20	patients	patient	NOUN
cord-000079-533xlisc	171	21	[	[	X
cord-000079-533xlisc	171	22	20	20	NUM
cord-000079-533xlisc	171	23	]	]	PUNCT
cord-000079-533xlisc	171	24	.	.	PUNCT
cord-000079-533xlisc	172	1	previous	previous	ADJ
cord-000079-533xlisc	172	2	studies	study	NOUN
cord-000079-533xlisc	172	3	have	have	AUX
cord-000079-533xlisc	172	4	demonstrated	demonstrate	VERB
cord-000079-533xlisc	172	5	that	that	SCONJ
cord-000079-533xlisc	172	6	retroviral	retroviral	ADJ
cord-000079-533xlisc	172	7	vectors	vector	NOUN
cord-000079-533xlisc	172	8	can	can	AUX
cord-000079-533xlisc	172	9	very	very	ADV
cord-000079-533xlisc	172	10	efficiently	efficiently	ADV
cord-000079-533xlisc	172	11	transduce	transduce	VERB
cord-000079-533xlisc	172	12	highly	highly	ADV
cord-000079-533xlisc	172	13	proliferative	proliferative	ADJ
cord-000079-533xlisc	172	14	monolayer	monolayer	NOUN
cord-000079-533xlisc	172	15	cultures	culture	NOUN
cord-000079-533xlisc	172	16	of	of	ADP
cord-000079-533xlisc	172	17	glioma	glioma	NOUN
cord-000079-533xlisc	172	18	cell	cell	NOUN
cord-000079-533xlisc	172	19	lines	line	NOUN
cord-000079-533xlisc	172	20	[	[	PUNCT
cord-000079-533xlisc	172	21	14	14	NUM
cord-000079-533xlisc	172	22	]	]	PUNCT
cord-000079-533xlisc	172	23	.	.	PUNCT
cord-000079-533xlisc	173	1	however	however	ADV
cord-000079-533xlisc	173	2	,	,	PUNCT
cord-000079-533xlisc	173	3	monolayer	monolayer	NOUN
cord-000079-533xlisc	173	4	cultures	culture	NOUN
cord-000079-533xlisc	173	5	change	change	VERB
cord-000079-533xlisc	173	6	their	their	PRON
cord-000079-533xlisc	173	7	geno	geno	NOUN
cord-000079-533xlisc	173	8	-	-	PUNCT
cord-000079-533xlisc	173	9	and	and	CCONJ
cord-000079-533xlisc	173	10	phenotypic	phenotypic	ADJ
cord-000079-533xlisc	173	11	characteristics	characteristic	NOUN
cord-000079-533xlisc	173	12	under	under	ADP
cord-000079-533xlisc	173	13	long	long	ADJ
cord-000079-533xlisc	173	14	term	term	NOUN
cord-000079-533xlisc	173	15	culture	culture	NOUN
cord-000079-533xlisc	173	16	and	and	CCONJ
cord-000079-533xlisc	173	17	thus	thus	ADV
cord-000079-533xlisc	173	18	are	be	AUX
cord-000079-533xlisc	173	19	not	not	PART
cord-000079-533xlisc	173	20	a	a	DET
cord-000079-533xlisc	173	21	suitable	suitable	ADJ
cord-000079-533xlisc	173	22	model	model	NOUN
cord-000079-533xlisc	173	23	to	to	PART
cord-000079-533xlisc	173	24	answer	answer	VERB
cord-000079-533xlisc	173	25	clinically	clinically	ADV
cord-000079-533xlisc	173	26	relevant	relevant	ADJ
cord-000079-533xlisc	173	27	questions	question	NOUN
cord-000079-533xlisc	173	28	[	[	X
cord-000079-533xlisc	173	29	26	26	NUM
cord-000079-533xlisc	173	30	]	]	PUNCT
cord-000079-533xlisc	173	31	.	.	PUNCT
cord-000079-533xlisc	174	1	for	for	ADP
cord-000079-533xlisc	174	2	in	in	ADP
cord-000079-533xlisc	174	3	vivo	vivo	ADJ
cord-000079-533xlisc	174	4	experiments	experiment	NOUN
cord-000079-533xlisc	174	5	,	,	PUNCT
cord-000079-533xlisc	174	6	we	we	PRON
cord-000079-533xlisc	174	7	selected	select	VERB
cord-000079-533xlisc	174	8	a	a	DET
cord-000079-533xlisc	174	9	high	high	ADJ
cord-000079-533xlisc	174	10	generation	generation	NOUN
cord-000079-533xlisc	174	11	xenograft	xenograft	PROPN
cord-000079-533xlisc	174	12	that	that	PRON
cord-000079-533xlisc	174	13	showed	show	VERB
cord-000079-533xlisc	174	14	both	both	PRON
cord-000079-533xlisc	174	15	angiogenic	angiogenic	ADJ
cord-000079-533xlisc	174	16	and	and	CCONJ
cord-000079-533xlisc	174	17	invasive	invasive	ADJ
cord-000079-533xlisc	174	18	features	feature	NOUN
cord-000079-533xlisc	174	19	and	and	CCONJ
cord-000079-533xlisc	174	20	recapitulated	recapitulate	VERB
cord-000079-533xlisc	174	21	the	the	DET
cord-000079-533xlisc	174	22	histology	histology	NOUN
cord-000079-533xlisc	174	23	of	of	ADP
cord-000079-533xlisc	174	24	the	the	DET
cord-000079-533xlisc	174	25	patient	patient	ADJ
cord-000079-533xlisc	174	26	lesion	lesion	NOUN
cord-000079-533xlisc	174	27	.	.	PUNCT
cord-000079-533xlisc	175	1	furthermore	furthermore	ADV
cord-000079-533xlisc	175	2	,	,	PUNCT
cord-000079-533xlisc	175	3	this	this	DET
cord-000079-533xlisc	175	4	xenograft	xenograft	PROPN
cord-000079-533xlisc	175	5	showed	show	VERB
cord-000079-533xlisc	175	6	a	a	DET
cord-000079-533xlisc	175	7	high	high	ADJ
cord-000079-533xlisc	175	8	level	level	NOUN
cord-000079-533xlisc	175	9	of	of	ADP
cord-000079-533xlisc	175	10	nestin	nestin	ADJ
cord-000079-533xlisc	175	11	expression	expression	NOUN
cord-000079-533xlisc	175	12	similar	similar	ADJ
cord-000079-533xlisc	175	13	to	to	ADP
cord-000079-533xlisc	175	14	the	the	DET
cord-000079-533xlisc	175	15	patient	patient	ADJ
cord-000079-533xlisc	175	16	material	material	NOUN
cord-000079-533xlisc	175	17	.	.	PUNCT
cord-000079-533xlisc	176	1	in	in	ADP
cord-000079-533xlisc	176	2	translational	translational	ADJ
cord-000079-533xlisc	176	3	research	research	NOUN
cord-000079-533xlisc	176	4	it	it	PRON
cord-000079-533xlisc	176	5	is	be	AUX
cord-000079-533xlisc	176	6	crucial	crucial	ADJ
cord-000079-533xlisc	176	7	to	to	PART
cord-000079-533xlisc	176	8	assure	assure	VERB
cord-000079-533xlisc	176	9	that	that	SCONJ
cord-000079-533xlisc	176	10	the	the	DET
cord-000079-533xlisc	176	11	experimental	experimental	ADJ
cord-000079-533xlisc	176	12	tumors	tumor	NOUN
cord-000079-533xlisc	176	13	truly	truly	ADV
cord-000079-533xlisc	176	14	reflect	reflect	VERB
cord-000079-533xlisc	176	15	the	the	DET
cord-000079-533xlisc	176	16	corresponding	corresponding	ADJ
cord-000079-533xlisc	176	17	patient	patient	NOUN
cord-000079-533xlisc	176	18	's	's	PART
cord-000079-533xlisc	176	19	tumor	tumor	NOUN
cord-000079-533xlisc	176	20	properties	property	NOUN
cord-000079-533xlisc	176	21	to	to	PART
cord-000079-533xlisc	176	22	avoid	avoid	VERB
cord-000079-533xlisc	176	23	using	use	VERB
cord-000079-533xlisc	176	24	non	non	ADJ
cord-000079-533xlisc	176	25	-	-	ADJ
cord-000079-533xlisc	176	26	relevant	relevant	ADJ
cord-000079-533xlisc	176	27	animal	animal	NOUN
cord-000079-533xlisc	176	28	models	model	NOUN
cord-000079-533xlisc	176	29	.	.	PUNCT
cord-000079-533xlisc	177	1	however	however	ADV
cord-000079-533xlisc	177	2	,	,	PUNCT
cord-000079-533xlisc	177	3	this	this	DET
cord-000079-533xlisc	177	4	strategy	strategy	NOUN
cord-000079-533xlisc	177	5	is	be	AUX
cord-000079-533xlisc	177	6	not	not	PART
cord-000079-533xlisc	177	7	common	common	ADJ
cord-000079-533xlisc	177	8	practice	practice	NOUN
cord-000079-533xlisc	177	9	yet	yet	ADV
cord-000079-533xlisc	177	10	,	,	PUNCT
cord-000079-533xlisc	177	11	based	base	VERB
cord-000079-533xlisc	177	12	on	on	ADP
cord-000079-533xlisc	177	13	the	the	DET
cord-000079-533xlisc	177	14	simplicity	simplicity	NOUN
cord-000079-533xlisc	177	15	of	of	ADP
cord-000079-533xlisc	177	16	using	use	VERB
cord-000079-533xlisc	177	17	established	establish	VERB
cord-000079-533xlisc	177	18	cell	cell	NOUN
cord-000079-533xlisc	177	19	lines	line	NOUN
cord-000079-533xlisc	177	20	for	for	ADP
cord-000079-533xlisc	177	21	in	in	ADP
cord-000079-533xlisc	177	22	vivo	vivo	ADJ
cord-000079-533xlisc	177	23	experiments	experiment	NOUN
cord-000079-533xlisc	177	24	.	.	PUNCT
cord-000079-533xlisc	178	1	we	we	PRON
cord-000079-533xlisc	178	2	showed	show	VERB
cord-000079-533xlisc	178	3	a	a	DET
cord-000079-533xlisc	178	4	high	high	ADJ
cord-000079-533xlisc	178	5	transduction	transduction	NOUN
cord-000079-533xlisc	178	6	efficiency	efficiency	NOUN
cord-000079-533xlisc	178	7	of	of	ADP
cord-000079-533xlisc	178	8	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	178	9	vectors	vector	NOUN
cord-000079-533xlisc	178	10	for	for	ADP
cord-000079-533xlisc	178	11	glioma	glioma	NOUN
cord-000079-533xlisc	178	12	cells	cell	NOUN
cord-000079-533xlisc	178	13	in	in	ADP
cord-000079-533xlisc	178	14	vivo	vivo	NOUN
cord-000079-533xlisc	178	15	,	,	PUNCT
cord-000079-533xlisc	178	16	whereas	whereas	SCONJ
cord-000079-533xlisc	178	17	retroviral	retroviral	ADJ
cord-000079-533xlisc	178	18	vectors	vector	NOUN
cord-000079-533xlisc	178	19	transduced	transduce	VERB
cord-000079-533xlisc	178	20	a	a	DET
cord-000079-533xlisc	178	21	few	few	ADJ
cord-000079-533xlisc	178	22	scattered	scatter	VERB
cord-000079-533xlisc	178	23	tumor	tumor	NOUN
cord-000079-533xlisc	178	24	cells	cell	NOUN
cord-000079-533xlisc	178	25	near	near	ADP
cord-000079-533xlisc	178	26	the	the	DET
cord-000079-533xlisc	178	27	injection	injection	NOUN
cord-000079-533xlisc	178	28	track	track	NOUN
cord-000079-533xlisc	178	29	.	.	PUNCT
cord-000079-533xlisc	179	1	this	this	PRON
cord-000079-533xlisc	179	2	is	be	AUX
cord-000079-533xlisc	179	3	in	in	ADP
cord-000079-533xlisc	179	4	contrast	contrast	NOUN
cord-000079-533xlisc	179	5	to	to	ADP
cord-000079-533xlisc	179	6	in	in	ADP
cord-000079-533xlisc	179	7	vivo	vivo	ADJ
cord-000079-533xlisc	179	8	studies	study	NOUN
cord-000079-533xlisc	179	9	by	by	ADP
cord-000079-533xlisc	179	10	others	other	NOUN
cord-000079-533xlisc	179	11	where	where	SCONJ
cord-000079-533xlisc	179	12	retroviral	retroviral	ADJ
cord-000079-533xlisc	179	13	vectors	vector	NOUN
cord-000079-533xlisc	179	14	were	be	AUX
cord-000079-533xlisc	179	15	very	very	ADV
cord-000079-533xlisc	179	16	efficient	efficient	ADJ
cord-000079-533xlisc	179	17	,	,	PUNCT
cord-000079-533xlisc	179	18	but	but	CCONJ
cord-000079-533xlisc	179	19	as	as	SCONJ
cord-000079-533xlisc	179	20	mentioned	mention	VERB
cord-000079-533xlisc	179	21	above	above	ADV
cord-000079-533xlisc	179	22	,	,	PUNCT
cord-000079-533xlisc	179	23	the	the	DET
cord-000079-533xlisc	179	24	models	model	NOUN
cord-000079-533xlisc	179	25	applied	apply	VERB
cord-000079-533xlisc	179	26	were	be	AUX
cord-000079-533xlisc	179	27	non	non	ADJ
cord-000079-533xlisc	179	28	-	-	ADJ
cord-000079-533xlisc	179	29	invasive	invasive	ADJ
cord-000079-533xlisc	179	30	,	,	PUNCT
cord-000079-533xlisc	179	31	based	base	VERB
cord-000079-533xlisc	179	32	on	on	ADP
cord-000079-533xlisc	179	33	cell	cell	NOUN
cord-000079-533xlisc	179	34	lines	line	NOUN
cord-000079-533xlisc	179	35	cultured	culture	VERB
cord-000079-533xlisc	179	36	as	as	ADP
cord-000079-533xlisc	179	37	monolayers	monolayer	NOUN
cord-000079-533xlisc	179	38	[	[	PUNCT
cord-000079-533xlisc	179	39	27	27	NUM
cord-000079-533xlisc	179	40	]	]	PUNCT
cord-000079-533xlisc	179	41	.	.	PUNCT
cord-000079-533xlisc	180	1	of	of	ADP
cord-000079-533xlisc	180	2	note	note	NOUN
cord-000079-533xlisc	180	3	,	,	PUNCT
cord-000079-533xlisc	180	4	the	the	DET
cord-000079-533xlisc	180	5	results	result	NOUN
cord-000079-533xlisc	180	6	of	of	ADP
cord-000079-533xlisc	180	7	clinical	clinical	ADJ
cord-000079-533xlisc	180	8	studies	study	NOUN
cord-000079-533xlisc	180	9	using	use	VERB
cord-000079-533xlisc	180	10	retroviral	retroviral	ADJ
cord-000079-533xlisc	180	11	vectors	vector	NOUN
cord-000079-533xlisc	180	12	showed	show	VERB
cord-000079-533xlisc	180	13	the	the	DET
cord-000079-533xlisc	180	14	same	same	ADJ
cord-000079-533xlisc	180	15	low	low	ADJ
cord-000079-533xlisc	180	16	transduction	transduction	NOUN
cord-000079-533xlisc	180	17	efficiency	efficiency	NOUN
cord-000079-533xlisc	180	18	as	as	SCONJ
cord-000079-533xlisc	180	19	observed	observe	VERB
cord-000079-533xlisc	180	20	in	in	ADP
cord-000079-533xlisc	180	21	our	our	PRON
cord-000079-533xlisc	180	22	model	model	NOUN
cord-000079-533xlisc	180	23	system	system	NOUN
cord-000079-533xlisc	180	24	[	[	PUNCT
cord-000079-533xlisc	180	25	12	12	NUM
cord-000079-533xlisc	180	26	]	]	PUNCT
cord-000079-533xlisc	180	27	.	.	PUNCT
cord-000079-533xlisc	181	1	this	this	DET
cord-000079-533xlisc	181	2	finding	finding	NOUN
cord-000079-533xlisc	181	3	provides	provide	VERB
cord-000079-533xlisc	181	4	further	further	ADJ
cord-000079-533xlisc	181	5	evidence	evidence	NOUN
cord-000079-533xlisc	181	6	that	that	SCONJ
cord-000079-533xlisc	181	7	the	the	DET
cord-000079-533xlisc	181	8	glioma	glioma	NOUN
cord-000079-533xlisc	181	9	model	model	NOUN
cord-000079-533xlisc	181	10	used	use	VERB
cord-000079-533xlisc	181	11	here	here	ADV
cord-000079-533xlisc	181	12	has	have	AUX
cord-000079-533xlisc	181	13	a	a	DET
cord-000079-533xlisc	181	14	higher	high	ADJ
cord-000079-533xlisc	181	15	predictive	predictive	ADJ
cord-000079-533xlisc	181	16	value	value	NOUN
cord-000079-533xlisc	181	17	for	for	ADP
cord-000079-533xlisc	181	18	the	the	DET
cord-000079-533xlisc	181	19	performance	performance	NOUN
cord-000079-533xlisc	181	20	of	of	ADP
cord-000079-533xlisc	181	21	a	a	DET
cord-000079-533xlisc	181	22	novel	novel	ADJ
cord-000079-533xlisc	181	23	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	181	24	approach	approach	NOUN
cord-000079-533xlisc	181	25	in	in	ADP
cord-000079-533xlisc	181	26	the	the	DET
cord-000079-533xlisc	181	27	clinic	clinic	NOUN
cord-000079-533xlisc	181	28	than	than	ADP
cord-000079-533xlisc	181	29	previous	previous	ADJ
cord-000079-533xlisc	181	30	animal	animal	NOUN
cord-000079-533xlisc	181	31	models	model	NOUN
cord-000079-533xlisc	181	32	.	.	PUNCT
cord-000079-533xlisc	182	1	the	the	DET
cord-000079-533xlisc	182	2	tropism	tropism	NOUN
cord-000079-533xlisc	182	3	for	for	ADP
cord-000079-533xlisc	182	4	glioma	glioma	NOUN
cord-000079-533xlisc	182	5	cells	cell	NOUN
cord-000079-533xlisc	182	6	was	be	AUX
cord-000079-533xlisc	182	7	more	more	ADV
cord-000079-533xlisc	182	8	specific	specific	ADJ
cord-000079-533xlisc	182	9	with	with	ADP
cord-000079-533xlisc	182	10	lcmv	lcmv	PROPN
cord-000079-533xlisc	182	11	-	-	PUNCT
cord-000079-533xlisc	182	12	gp	gp	PROPN
cord-000079-533xlisc	182	13	lentiviral	lentiviral	NOUN
cord-000079-533xlisc	182	14	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	182	15	vectors	vector	NOUN
cord-000079-533xlisc	182	16	,	,	PUNCT
cord-000079-533xlisc	182	17	as	as	SCONJ
cord-000079-533xlisc	182	18	vsv	vsv	PROPN
cord-000079-533xlisc	182	19	-	-	PUNCT
cord-000079-533xlisc	182	20	g	g	NOUN
cord-000079-533xlisc	182	21	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	182	22	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	182	23	vectors	vector	NOUN
cord-000079-533xlisc	182	24	also	also	ADV
cord-000079-533xlisc	182	25	transduced	transduce	VERB
cord-000079-533xlisc	182	26	few	few	ADJ
cord-000079-533xlisc	182	27	normal	normal	ADJ
cord-000079-533xlisc	182	28	brain	brain	NOUN
cord-000079-533xlisc	182	29	cells	cell	NOUN
cord-000079-533xlisc	182	30	in	in	ADP
cord-000079-533xlisc	182	31	invasive	invasive	ADJ
cord-000079-533xlisc	182	32	areas	area	NOUN
cord-000079-533xlisc	182	33	.	.	PUNCT
cord-000079-533xlisc	183	1	in	in	ADP
cord-000079-533xlisc	183	2	previous	previous	ADJ
cord-000079-533xlisc	183	3	studies	study	NOUN
cord-000079-533xlisc	183	4	using	use	VERB
cord-000079-533xlisc	183	5	a	a	DET
cord-000079-533xlisc	183	6	rat	rat	NOUN
cord-000079-533xlisc	183	7	glioma	glioma	NOUN
cord-000079-533xlisc	183	8	model	model	NOUN
cord-000079-533xlisc	183	9	,	,	PUNCT
cord-000079-533xlisc	183	10	we	we	PRON
cord-000079-533xlisc	183	11	also	also	ADV
cord-000079-533xlisc	183	12	showed	show	VERB
cord-000079-533xlisc	183	13	a	a	DET
cord-000079-533xlisc	183	14	more	more	ADV
cord-000079-533xlisc	183	15	specific	specific	ADJ
cord-000079-533xlisc	183	16	transduction	transduction	NOUN
cord-000079-533xlisc	183	17	of	of	ADP
cord-000079-533xlisc	183	18	glioma	glioma	NOUN
cord-000079-533xlisc	183	19	cells	cell	NOUN
cord-000079-533xlisc	183	20	by	by	ADP
cord-000079-533xlisc	183	21	lcmv	lcmv	PROPN
cord-000079-533xlisc	183	22	-	-	PUNCT
cord-000079-533xlisc	183	23	gp	gp	NOUN
cord-000079-533xlisc	183	24	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	183	25	vectors	vector	NOUN
cord-000079-533xlisc	183	26	compared	compare	VERB
cord-000079-533xlisc	183	27	to	to	ADP
cord-000079-533xlisc	183	28	vsv	vsv	PROPN
cord-000079-533xlisc	183	29	-	-	PROPN
cord-000079-533xlisc	183	30	g	g	NOUN
cord-000079-533xlisc	183	31	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	183	32	vectors	vector	NOUN
cord-000079-533xlisc	183	33	[	[	X
cord-000079-533xlisc	183	34	18	18	NUM
cord-000079-533xlisc	183	35	,	,	PUNCT
cord-000079-533xlisc	183	36	19	19	NUM
cord-000079-533xlisc	183	37	]	]	PUNCT
cord-000079-533xlisc	183	38	.	.	PUNCT
cord-000079-533xlisc	184	1	in	in	ADP
cord-000079-533xlisc	184	2	fact	fact	NOUN
cord-000079-533xlisc	184	3	,	,	PUNCT
cord-000079-533xlisc	184	4	in	in	ADP
cord-000079-533xlisc	184	5	these	these	DET
cord-000079-533xlisc	184	6	studies	study	NOUN
cord-000079-533xlisc	184	7	,	,	PUNCT
cord-000079-533xlisc	184	8	the	the	DET
cord-000079-533xlisc	184	9	vsv	vsv	PROPN
cord-000079-533xlisc	184	10	-	-	PUNCT
cord-000079-533xlisc	184	11	g	g	NOUN
cord-000079-533xlisc	184	12	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	184	13	vectors	vector	NOUN
cord-000079-533xlisc	184	14	transduced	transduce	VERB
cord-000079-533xlisc	184	15	normal	normal	ADJ
cord-000079-533xlisc	184	16	brain	brain	NOUN
cord-000079-533xlisc	184	17	cells	cell	NOUN
cord-000079-533xlisc	184	18	at	at	ADP
cord-000079-533xlisc	184	19	a	a	DET
cord-000079-533xlisc	184	20	much	much	ADV
cord-000079-533xlisc	184	21	higher	high	ADJ
cord-000079-533xlisc	184	22	frequency	frequency	NOUN
cord-000079-533xlisc	184	23	than	than	ADP
cord-000079-533xlisc	184	24	in	in	ADP
cord-000079-533xlisc	184	25	this	this	DET
cord-000079-533xlisc	184	26	study	study	NOUN
cord-000079-533xlisc	184	27	.	.	PUNCT
cord-000079-533xlisc	185	1	this	this	PRON
cord-000079-533xlisc	185	2	can	can	AUX
cord-000079-533xlisc	185	3	be	be	AUX
cord-000079-533xlisc	185	4	explained	explain	VERB
cord-000079-533xlisc	185	5	by	by	ADP
cord-000079-533xlisc	185	6	the	the	DET
cord-000079-533xlisc	185	7	mode	mode	NOUN
cord-000079-533xlisc	185	8	of	of	ADP
cord-000079-533xlisc	185	9	vector	vector	NOUN
cord-000079-533xlisc	185	10	delivery	delivery	NOUN
cord-000079-533xlisc	185	11	,	,	PUNCT
cord-000079-533xlisc	185	12	because	because	SCONJ
cord-000079-533xlisc	185	13	in	in	ADP
cord-000079-533xlisc	185	14	the	the	DET
cord-000079-533xlisc	185	15	previous	previous	ADJ
cord-000079-533xlisc	185	16	studies	study	NOUN
cord-000079-533xlisc	185	17	,	,	PUNCT
cord-000079-533xlisc	185	18	we	we	PRON
cord-000079-533xlisc	185	19	injected	inject	VERB
cord-000079-533xlisc	185	20	the	the	DET
cord-000079-533xlisc	185	21	vectors	vector	NOUN
cord-000079-533xlisc	185	22	both	both	CCONJ
cord-000079-533xlisc	185	23	into	into	ADP
cord-000079-533xlisc	185	24	the	the	DET
cord-000079-533xlisc	185	25	tumor	tumor	NOUN
cord-000079-533xlisc	185	26	core	core	NOUN
cord-000079-533xlisc	185	27	as	as	ADV
cord-000079-533xlisc	185	28	well	well	ADV
cord-000079-533xlisc	185	29	as	as	ADP
cord-000079-533xlisc	185	30	into	into	ADP
cord-000079-533xlisc	185	31	tumor	tumor	NOUN
cord-000079-533xlisc	185	32	border	border	NOUN
cord-000079-533xlisc	185	33	areas	area	NOUN
cord-000079-533xlisc	185	34	.	.	PUNCT
cord-000079-533xlisc	186	1	in	in	ADP
cord-000079-533xlisc	186	2	the	the	DET
cord-000079-533xlisc	186	3	present	present	ADJ
cord-000079-533xlisc	186	4	study	study	NOUN
cord-000079-533xlisc	186	5	,	,	PUNCT
cord-000079-533xlisc	186	6	we	we	PRON
cord-000079-533xlisc	186	7	injected	inject	VERB
cord-000079-533xlisc	186	8	the	the	DET
cord-000079-533xlisc	186	9	vectors	vector	NOUN
cord-000079-533xlisc	186	10	into	into	ADP
cord-000079-533xlisc	186	11	the	the	DET
cord-000079-533xlisc	186	12	tumor	tumor	NOUN
cord-000079-533xlisc	186	13	core	core	NOUN
cord-000079-533xlisc	186	14	only	only	ADV
cord-000079-533xlisc	186	15	using	use	VERB
cord-000079-533xlisc	186	16	convection	convection	NOUN
cord-000079-533xlisc	186	17	enhanced	enhance	VERB
cord-000079-533xlisc	186	18	delivery	delivery	NOUN
cord-000079-533xlisc	186	19	.	.	PUNCT
cord-000079-533xlisc	187	1	we	we	PRON
cord-000079-533xlisc	187	2	used	use	VERB
cord-000079-533xlisc	187	3	this	this	DET
cord-000079-533xlisc	187	4	method	method	NOUN
cord-000079-533xlisc	187	5	because	because	SCONJ
cord-000079-533xlisc	187	6	it	it	PRON
cord-000079-533xlisc	187	7	results	result	VERB
cord-000079-533xlisc	187	8	in	in	ADP
cord-000079-533xlisc	187	9	a	a	DET
cord-000079-533xlisc	187	10	high	high	ADJ
cord-000079-533xlisc	187	11	distribution	distribution	NOUN
cord-000079-533xlisc	187	12	volume	volume	NOUN
cord-000079-533xlisc	187	13	of	of	ADP
cord-000079-533xlisc	187	14	drug	drug	NOUN
cord-000079-533xlisc	187	15	and	and	CCONJ
cord-000079-533xlisc	187	16	vector	vector	NOUN
cord-000079-533xlisc	187	17	and	and	CCONJ
cord-000079-533xlisc	187	18	is	be	AUX
cord-000079-533xlisc	187	19	currently	currently	ADV
cord-000079-533xlisc	187	20	used	use	VERB
cord-000079-533xlisc	187	21	as	as	ADP
cord-000079-533xlisc	187	22	a	a	DET
cord-000079-533xlisc	187	23	delivery	delivery	NOUN
cord-000079-533xlisc	187	24	method	method	NOUN
cord-000079-533xlisc	187	25	in	in	ADP
cord-000079-533xlisc	187	26	clinical	clinical	ADJ
cord-000079-533xlisc	187	27	studies	study	NOUN
cord-000079-533xlisc	187	28	[	[	X
cord-000079-533xlisc	187	29	28	28	NUM
cord-000079-533xlisc	187	30	]	]	PUNCT
cord-000079-533xlisc	187	31	.	.	PUNCT
cord-000079-533xlisc	188	1	in	in	ADP
cord-000079-533xlisc	188	2	addition	addition	NOUN
cord-000079-533xlisc	188	3	,	,	PUNCT
cord-000079-533xlisc	188	4	the	the	DET
cord-000079-533xlisc	188	5	tumor	tumor	NOUN
cord-000079-533xlisc	188	6	model	model	NOUN
cord-000079-533xlisc	188	7	we	we	PRON
cord-000079-533xlisc	188	8	apply	apply	VERB
cord-000079-533xlisc	188	9	here	here	ADV
cord-000079-533xlisc	188	10	is	be	AUX
cord-000079-533xlisc	188	11	highly	highly	ADV
cord-000079-533xlisc	188	12	invasive	invasive	ADJ
cord-000079-533xlisc	188	13	and	and	CCONJ
cord-000079-533xlisc	188	14	lacks	lack	VERB
cord-000079-533xlisc	188	15	a	a	DET
cord-000079-533xlisc	188	16	sharply	sharply	ADV
cord-000079-533xlisc	188	17	demarcated	demarcate	VERB
cord-000079-533xlisc	188	18	brain	brain	NOUN
cord-000079-533xlisc	188	19	tumor	tumor	NOUN
cord-000079-533xlisc	188	20	/	/	SYM
cord-000079-533xlisc	188	21	normal	normal	ADJ
cord-000079-533xlisc	188	22	brain	brain	NOUN
cord-000079-533xlisc	188	23	interface	interface	NOUN
cord-000079-533xlisc	188	24	,	,	PUNCT
cord-000079-533xlisc	188	25	present	present	ADJ
cord-000079-533xlisc	188	26	in	in	ADP
cord-000079-533xlisc	188	27	the	the	DET
cord-000079-533xlisc	188	28	rat	rat	NOUN
cord-000079-533xlisc	188	29	glioma	glioma	NOUN
cord-000079-533xlisc	188	30	model	model	NOUN
cord-000079-533xlisc	188	31	.	.	PUNCT
cord-000079-533xlisc	189	1	another	another	DET
cord-000079-533xlisc	189	2	explanation	explanation	NOUN
cord-000079-533xlisc	189	3	could	could	AUX
cord-000079-533xlisc	189	4	be	be	AUX
cord-000079-533xlisc	189	5	the	the	DET
cord-000079-533xlisc	189	6	species	species	NOUN
cord-000079-533xlisc	189	7	difference	difference	NOUN
cord-000079-533xlisc	189	8	as	as	SCONJ
cord-000079-533xlisc	189	9	we	we	PRON
cord-000079-533xlisc	189	10	used	use	VERB
cord-000079-533xlisc	189	11	human	human	ADJ
cord-000079-533xlisc	189	12	glioma	glioma	NOUN
cord-000079-533xlisc	189	13	cells	cell	NOUN
cord-000079-533xlisc	189	14	in	in	ADP
cord-000079-533xlisc	189	15	this	this	DET
cord-000079-533xlisc	189	16	study	study	NOUN
cord-000079-533xlisc	189	17	in	in	ADP
cord-000079-533xlisc	189	18	contrast	contrast	NOUN
cord-000079-533xlisc	189	19	to	to	ADP
cord-000079-533xlisc	189	20	rat	rat	NOUN
cord-000079-533xlisc	189	21	glioma	glioma	NOUN
cord-000079-533xlisc	189	22	cells	cell	NOUN
cord-000079-533xlisc	189	23	in	in	ADP
cord-000079-533xlisc	189	24	the	the	DET
cord-000079-533xlisc	189	25	previous	previous	ADJ
cord-000079-533xlisc	189	26	work	work	NOUN
cord-000079-533xlisc	189	27	.	.	PUNCT
cord-000079-533xlisc	190	1	vsv	vsv	PROPN
cord-000079-533xlisc	190	2	-	-	PROPN
cord-000079-533xlisc	190	3	g	g	NOUN
cord-000079-533xlisc	190	4	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	190	5	vectors	vector	NOUN
cord-000079-533xlisc	190	6	might	might	AUX
cord-000079-533xlisc	190	7	have	have	VERB
cord-000079-533xlisc	190	8	a	a	DET
cord-000079-533xlisc	190	9	higher	high	ADJ
cord-000079-533xlisc	190	10	tropism	tropism	NOUN
cord-000079-533xlisc	190	11	for	for	ADP
cord-000079-533xlisc	190	12	human	human	ADJ
cord-000079-533xlisc	190	13	glioma	glioma	NOUN
cord-000079-533xlisc	190	14	cells	cell	NOUN
cord-000079-533xlisc	190	15	than	than	ADP
cord-000079-533xlisc	190	16	for	for	ADP
cord-000079-533xlisc	190	17	rat	rat	NOUN
cord-000079-533xlisc	190	18	normal	normal	ADJ
cord-000079-533xlisc	190	19	host	host	NOUN
cord-000079-533xlisc	190	20	cells	cell	NOUN
cord-000079-533xlisc	190	21	.	.	PUNCT
cord-000079-533xlisc	191	1	however	however	ADV
cord-000079-533xlisc	191	2	,	,	PUNCT
cord-000079-533xlisc	191	3	as	as	SCONJ
cord-000079-533xlisc	191	4	the	the	DET
cord-000079-533xlisc	191	5	receptor	receptor	NOUN
cord-000079-533xlisc	191	6	for	for	ADP
cord-000079-533xlisc	191	7	vsv	vsv	PROPN
cord-000079-533xlisc	191	8	-	-	PROPN
cord-000079-533xlisc	191	9	g	g	PROPN
cord-000079-533xlisc	191	10	is	be	AUX
cord-000079-533xlisc	191	11	unknown	unknown	ADJ
cord-000079-533xlisc	191	12	[	[	X
cord-000079-533xlisc	191	13	29	29	NUM
cord-000079-533xlisc	191	14	]	]	PUNCT
cord-000079-533xlisc	191	15	,	,	PUNCT
cord-000079-533xlisc	191	16	this	this	PRON
cord-000079-533xlisc	191	17	remains	remain	VERB
cord-000079-533xlisc	191	18	a	a	DET
cord-000079-533xlisc	191	19	hypothesis	hypothesis	NOUN
cord-000079-533xlisc	191	20	.	.	PUNCT
cord-000079-533xlisc	192	1	the	the	DET
cord-000079-533xlisc	192	2	targeting	targeting	NOUN
cord-000079-533xlisc	192	3	of	of	ADP
cord-000079-533xlisc	192	4	cancer	cancer	NOUN
cord-000079-533xlisc	192	5	stem	stem	NOUN
cord-000079-533xlisc	192	6	cells	cell	NOUN
cord-000079-533xlisc	192	7	or	or	CCONJ
cord-000079-533xlisc	192	8	cancer	cancer	NOUN
cord-000079-533xlisc	192	9	stem	stem	NOUN
cord-000079-533xlisc	192	10	-	-	PUNCT
cord-000079-533xlisc	192	11	like	like	ADJ
cord-000079-533xlisc	192	12	cells	cell	NOUN
cord-000079-533xlisc	192	13	in	in	ADP
cord-000079-533xlisc	192	14	human	human	ADJ
cord-000079-533xlisc	192	15	tumors	tumor	NOUN
cord-000079-533xlisc	192	16	including	include	VERB
cord-000079-533xlisc	192	17	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	192	18	has	have	AUX
cord-000079-533xlisc	192	19	recently	recently	ADV
cord-000079-533xlisc	192	20	evolved	evolve	VERB
cord-000079-533xlisc	192	21	as	as	ADP
cord-000079-533xlisc	192	22	a	a	DET
cord-000079-533xlisc	192	23	major	major	ADJ
cord-000079-533xlisc	192	24	aim	aim	NOUN
cord-000079-533xlisc	192	25	in	in	ADP
cord-000079-533xlisc	192	26	cancer	cancer	NOUN
cord-000079-533xlisc	192	27	therapy	therapy	NOUN
cord-000079-533xlisc	192	28	.	.	PUNCT
cord-000079-533xlisc	193	1	these	these	DET
cord-000079-533xlisc	193	2	stem	stem	NOUN
cord-000079-533xlisc	193	3	cells	cell	NOUN
cord-000079-533xlisc	193	4	are	be	AUX
cord-000079-533xlisc	193	5	suggested	suggest	VERB
cord-000079-533xlisc	193	6	to	to	PART
cord-000079-533xlisc	193	7	initiate	initiate	VERB
cord-000079-533xlisc	193	8	cancer	cancer	NOUN
cord-000079-533xlisc	193	9	and	and	CCONJ
cord-000079-533xlisc	193	10	might	might	AUX
cord-000079-533xlisc	193	11	be	be	AUX
cord-000079-533xlisc	193	12	resistant	resistant	ADJ
cord-000079-533xlisc	193	13	to	to	ADP
cord-000079-533xlisc	193	14	therapy	therapy	NOUN
cord-000079-533xlisc	193	15	,	,	PUNCT
cord-000079-533xlisc	193	16	thus	thus	ADV
cord-000079-533xlisc	193	17	being	be	AUX
cord-000079-533xlisc	193	18	responsible	responsible	ADJ
cord-000079-533xlisc	193	19	for	for	ADP
cord-000079-533xlisc	193	20	tumor	tumor	NOUN
cord-000079-533xlisc	193	21	recurrence	recurrence	NOUN
cord-000079-533xlisc	193	22	[	[	X
cord-000079-533xlisc	193	23	30	30	NUM
cord-000079-533xlisc	193	24	]	]	PUNCT
cord-000079-533xlisc	193	25	[	[	X
cord-000079-533xlisc	193	26	31	31	NUM
cord-000079-533xlisc	193	27	]	]	PUNCT
cord-000079-533xlisc	193	28	[	[	X
cord-000079-533xlisc	193	29	32	32	NUM
cord-000079-533xlisc	193	30	]	]	PUNCT
cord-000079-533xlisc	193	31	.	.	PUNCT
cord-000079-533xlisc	194	1	yet	yet	ADV
cord-000079-533xlisc	194	2	,	,	PUNCT
cord-000079-533xlisc	194	3	recent	recent	ADJ
cord-000079-533xlisc	194	4	studies	study	NOUN
cord-000079-533xlisc	194	5	have	have	AUX
cord-000079-533xlisc	194	6	initiated	initiate	VERB
cord-000079-533xlisc	194	7	a	a	DET
cord-000079-533xlisc	194	8	controversial	controversial	ADJ
cord-000079-533xlisc	194	9	discussion	discussion	NOUN
cord-000079-533xlisc	194	10	whether	whether	SCONJ
cord-000079-533xlisc	194	11	cancer	cancer	NOUN
cord-000079-533xlisc	194	12	stem	stem	NOUN
cord-000079-533xlisc	194	13	cells	cell	NOUN
cord-000079-533xlisc	194	14	really	really	ADV
cord-000079-533xlisc	194	15	exist	exist	VERB
cord-000079-533xlisc	194	16	[	[	PUNCT
cord-000079-533xlisc	194	17	33	33	NUM
cord-000079-533xlisc	194	18	,	,	PUNCT
cord-000079-533xlisc	194	19	34	34	NUM
cord-000079-533xlisc	194	20	]	]	PUNCT
cord-000079-533xlisc	194	21	.	.	PUNCT
cord-000079-533xlisc	195	1	therefore	therefore	ADV
cord-000079-533xlisc	195	2	,	,	PUNCT
cord-000079-533xlisc	195	3	we	we	PRON
cord-000079-533xlisc	195	4	use	use	VERB
cord-000079-533xlisc	195	5	the	the	DET
cord-000079-533xlisc	195	6	term	term	NOUN
cord-000079-533xlisc	195	7	''	''	PUNCT
cord-000079-533xlisc	195	8	cancer	cancer	NOUN
cord-000079-533xlisc	195	9	stem	stem	NOUN
cord-000079-533xlisc	195	10	-	-	PUNCT
cord-000079-533xlisc	195	11	like	like	ADJ
cord-000079-533xlisc	195	12	cells	cell	NOUN
cord-000079-533xlisc	195	13	''	''	PUNCT
cord-000079-533xlisc	195	14	in	in	ADP
cord-000079-533xlisc	195	15	our	our	PRON
cord-000079-533xlisc	195	16	study	study	NOUN
cord-000079-533xlisc	195	17	to	to	PART
cord-000079-533xlisc	195	18	designate	designate	VERB
cord-000079-533xlisc	195	19	cells	cell	NOUN
cord-000079-533xlisc	195	20	which	which	PRON
cord-000079-533xlisc	195	21	have	have	VERB
cord-000079-533xlisc	195	22	certain	certain	ADJ
cord-000079-533xlisc	195	23	stem	stem	NOUN
cord-000079-533xlisc	195	24	-	-	PUNCT
cord-000079-533xlisc	195	25	like	like	ADJ
cord-000079-533xlisc	195	26	properties	property	NOUN
cord-000079-533xlisc	195	27	described	describe	VERB
cord-000079-533xlisc	195	28	previously	previously	ADV
cord-000079-533xlisc	195	29	.	.	PUNCT
cord-000079-533xlisc	196	1	we	we	PRON
cord-000079-533xlisc	196	2	showed	show	VERB
cord-000079-533xlisc	196	3	that	that	SCONJ
cord-000079-533xlisc	196	4	both	both	DET
cord-000079-533xlisc	196	5	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	196	6	vectors	vector	NOUN
cord-000079-533xlisc	196	7	transduced	transduce	VERB
cord-000079-533xlisc	196	8	cd133	cd133	PROPN
cord-000079-533xlisc	196	9	-	-	PUNCT
cord-000079-533xlisc	196	10	positive	positive	ADJ
cord-000079-533xlisc	196	11	and	and	CCONJ
cord-000079-533xlisc	196	12	cd133	cd133	ADV
cord-000079-533xlisc	196	13	-	-	PUNCT
cord-000079-533xlisc	196	14	negative	negative	ADJ
cord-000079-533xlisc	196	15	cells	cell	NOUN
cord-000079-533xlisc	196	16	.	.	PUNCT
cord-000079-533xlisc	197	1	cd133	cd133	ADV
cord-000079-533xlisc	197	2	-	-	PUNCT
cord-000079-533xlisc	197	3	positive	positive	ADJ
cord-000079-533xlisc	197	4	cells	cell	NOUN
cord-000079-533xlisc	197	5	have	have	AUX
cord-000079-533xlisc	197	6	been	be	AUX
cord-000079-533xlisc	197	7	identified	identify	VERB
cord-000079-533xlisc	197	8	as	as	ADP
cord-000079-533xlisc	197	9	cancer	cancer	NOUN
cord-000079-533xlisc	197	10	initiating	initiate	VERB
cord-000079-533xlisc	197	11	cells	cell	NOUN
cord-000079-533xlisc	197	12	and	and	CCONJ
cord-000079-533xlisc	197	13	cancer	cancer	NOUN
cord-000079-533xlisc	197	14	stem	stem	NOUN
cord-000079-533xlisc	197	15	cells	cell	NOUN
cord-000079-533xlisc	197	16	in	in	ADP
cord-000079-533xlisc	197	17	many	many	ADJ
cord-000079-533xlisc	197	18	different	different	ADJ
cord-000079-533xlisc	197	19	cancers	cancer	NOUN
cord-000079-533xlisc	197	20	including	include	VERB
cord-000079-533xlisc	197	21	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	197	22	[	[	PUNCT
cord-000079-533xlisc	197	23	30	30	NUM
cord-000079-533xlisc	197	24	,	,	PUNCT
cord-000079-533xlisc	197	25	35	35	NUM
cord-000079-533xlisc	197	26	]	]	PUNCT
cord-000079-533xlisc	197	27	.	.	PUNCT
cord-000079-533xlisc	198	1	however	however	ADV
cord-000079-533xlisc	198	2	,	,	PUNCT
cord-000079-533xlisc	198	3	more	more	ADV
cord-000079-533xlisc	198	4	recent	recent	ADJ
cord-000079-533xlisc	198	5	reports	report	NOUN
cord-000079-533xlisc	198	6	questioned	question	VERB
cord-000079-533xlisc	198	7	these	these	DET
cord-000079-533xlisc	198	8	findings	finding	NOUN
cord-000079-533xlisc	198	9	showing	show	VERB
cord-000079-533xlisc	198	10	that	that	SCONJ
cord-000079-533xlisc	198	11	cd133	cd133	PROPN
cord-000079-533xlisc	198	12	-	-	PUNCT
cord-000079-533xlisc	198	13	negative	negative	ADJ
cord-000079-533xlisc	198	14	popopulations	popopulation	NOUN
cord-000079-533xlisc	198	15	can	can	AUX
cord-000079-533xlisc	198	16	include	include	VERB
cord-000079-533xlisc	198	17	cancer	cancer	NOUN
cord-000079-533xlisc	198	18	initiating	initiate	VERB
cord-000079-533xlisc	198	19	cells	cell	NOUN
cord-000079-533xlisc	198	20	as	as	ADV
cord-000079-533xlisc	198	21	well	well	ADV
cord-000079-533xlisc	198	22	[	[	PUNCT
cord-000079-533xlisc	198	23	36	36	NUM
cord-000079-533xlisc	198	24	,	,	PUNCT
cord-000079-533xlisc	198	25	37	37	NUM
cord-000079-533xlisc	198	26	]	]	PUNCT
cord-000079-533xlisc	198	27	.	.	PUNCT
cord-000079-533xlisc	199	1	the	the	DET
cord-000079-533xlisc	199	2	efficient	efficient	ADJ
cord-000079-533xlisc	199	3	targeting	targeting	NOUN
cord-000079-533xlisc	199	4	of	of	ADP
cord-000079-533xlisc	199	5	cd133	cd133	PROPN
cord-000079-533xlisc	199	6	-	-	PUNCT
cord-000079-533xlisc	199	7	positive	positive	ADJ
cord-000079-533xlisc	199	8	and	and	CCONJ
cord-000079-533xlisc	199	9	cd133	cd133	ADV
cord-000079-533xlisc	199	10	-	-	PUNCT
cord-000079-533xlisc	199	11	negative	negative	ADJ
cord-000079-533xlisc	199	12	glioma	glioma	NOUN
cord-000079-533xlisc	199	13	cells	cell	NOUN
cord-000079-533xlisc	199	14	has	have	AUX
cord-000079-533xlisc	199	15	also	also	ADV
cord-000079-533xlisc	199	16	been	be	AUX
cord-000079-533xlisc	199	17	described	describe	VERB
cord-000079-533xlisc	199	18	for	for	ADP
cord-000079-533xlisc	199	19	adenoviral	adenoviral	ADJ
cord-000079-533xlisc	199	20	vectors	vector	NOUN
cord-000079-533xlisc	199	21	[	[	PUNCT
cord-000079-533xlisc	199	22	38	38	NUM
cord-000079-533xlisc	199	23	,	,	PUNCT
cord-000079-533xlisc	199	24	39	39	NUM
cord-000079-533xlisc	199	25	]	]	PUNCT
cord-000079-533xlisc	199	26	.	.	PUNCT
cord-000079-533xlisc	200	1	we	we	PRON
cord-000079-533xlisc	200	2	further	far	ADV
cord-000079-533xlisc	200	3	demonstrated	demonstrate	VERB
cord-000079-533xlisc	200	4	that	that	SCONJ
cord-000079-533xlisc	200	5	sorted	sorted	ADJ
cord-000079-533xlisc	200	6	cells	cell	NOUN
cord-000079-533xlisc	200	7	from	from	ADP
cord-000079-533xlisc	200	8	tumors	tumor	NOUN
cord-000079-533xlisc	200	9	transduced	transduce	VERB
cord-000079-533xlisc	200	10	either	either	CCONJ
cord-000079-533xlisc	200	11	by	by	ADP
cord-000079-533xlisc	200	12	lentiviral	lentiviral	PROPN
cord-000079-533xlisc	200	13	lcmv	lcmv	PROPN
cord-000079-533xlisc	200	14	-	-	PUNCT
cord-000079-533xlisc	200	15	gp	gp	PROPN
cord-000079-533xlisc	200	16	or	or	CCONJ
cord-000079-533xlisc	200	17	vsv	vsv	PROPN
cord-000079-533xlisc	200	18	-	-	PUNCT
cord-000079-533xlisc	200	19	g	g	NOUN
cord-000079-533xlisc	200	20	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	200	21	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	200	22	vectors	vector	NOUN
cord-000079-533xlisc	200	23	had	have	VERB
cord-000079-533xlisc	200	24	the	the	DET
cord-000079-533xlisc	200	25	ability	ability	NOUN
cord-000079-533xlisc	200	26	to	to	PART
cord-000079-533xlisc	200	27	form	form	VERB
cord-000079-533xlisc	200	28	spheroids	spheroid	NOUN
cord-000079-533xlisc	200	29	upon	upon	SCONJ
cord-000079-533xlisc	200	30	culturing	culture	VERB
cord-000079-533xlisc	200	31	in	in	ADP
cord-000079-533xlisc	200	32	neural	neural	ADJ
cord-000079-533xlisc	200	33	basal	basal	ADJ
cord-000079-533xlisc	200	34	medium	medium	NOUN
cord-000079-533xlisc	200	35	supplemented	supplement	VERB
cord-000079-533xlisc	200	36	with	with	ADP
cord-000079-533xlisc	200	37	egf	egf	NOUN
cord-000079-533xlisc	200	38	and	and	CCONJ
cord-000079-533xlisc	200	39	bfgf	bfgf	PROPN
cord-000079-533xlisc	200	40	.	.	PUNCT
cord-000079-533xlisc	201	1	spheroids	spheroid	NOUN
cord-000079-533xlisc	201	2	from	from	ADP
cord-000079-533xlisc	201	3	both	both	CCONJ
cord-000079-533xlisc	201	4	sorted	sorted	ADJ
cord-000079-533xlisc	201	5	cell	cell	NOUN
cord-000079-533xlisc	201	6	populations	population	NOUN
cord-000079-533xlisc	201	7	expressed	express	VERB
cord-000079-533xlisc	201	8	the	the	DET
cord-000079-533xlisc	201	9	neural	neural	ADJ
cord-000079-533xlisc	201	10	stem	stem	NOUN
cord-000079-533xlisc	201	11	cell	cell	NOUN
cord-000079-533xlisc	201	12	markers	marker	NOUN
cord-000079-533xlisc	201	13	nestin	nestin	ADV
cord-000079-533xlisc	201	14	and	and	CCONJ
cord-000079-533xlisc	201	15	sox2	sox2	PROPN
cord-000079-533xlisc	201	16	and	and	CCONJ
cord-000079-533xlisc	201	17	showed	show	VERB
cord-000079-533xlisc	201	18	the	the	DET
cord-000079-533xlisc	201	19	ability	ability	NOUN
cord-000079-533xlisc	201	20	to	to	PART
cord-000079-533xlisc	201	21	express	express	VERB
cord-000079-533xlisc	201	22	the	the	DET
cord-000079-533xlisc	201	23	differentiation	differentiation	NOUN
cord-000079-533xlisc	201	24	markers	marker	NOUN
cord-000079-533xlisc	201	25	gfap	gfap	ADJ
cord-000079-533xlisc	201	26	and	and	CCONJ
cord-000079-533xlisc	201	27	b	b	NOUN
cord-000079-533xlisc	201	28	-	-	PUNCT
cord-000079-533xlisc	201	29	tubuliniii	tubuliniii	NOUN
cord-000079-533xlisc	201	30	under	under	ADP
cord-000079-533xlisc	201	31	serum	serum	NOUN
cord-000079-533xlisc	201	32	conditions	condition	NOUN
cord-000079-533xlisc	201	33	.	.	PUNCT
cord-000079-533xlisc	202	1	these	these	DET
cord-000079-533xlisc	202	2	properties	property	NOUN
cord-000079-533xlisc	202	3	have	have	AUX
cord-000079-533xlisc	202	4	been	be	AUX
cord-000079-533xlisc	202	5	described	describe	VERB
cord-000079-533xlisc	202	6	for	for	ADP
cord-000079-533xlisc	202	7	neural	neural	ADJ
cord-000079-533xlisc	202	8	progenitor	progenitor	NOUN
cord-000079-533xlisc	202	9	cells	cell	NOUN
cord-000079-533xlisc	202	10	[	[	PUNCT
cord-000079-533xlisc	202	11	40	40	NUM
cord-000079-533xlisc	202	12	]	]	PUNCT
cord-000079-533xlisc	202	13	as	as	ADV
cord-000079-533xlisc	202	14	well	well	ADV
cord-000079-533xlisc	202	15	as	as	ADP
cord-000079-533xlisc	202	16	for	for	ADP
cord-000079-533xlisc	202	17	cancer	cancer	NOUN
cord-000079-533xlisc	202	18	stem	stem	NOUN
cord-000079-533xlisc	202	19	-	-	PUNCT
cord-000079-533xlisc	202	20	like	like	ADJ
cord-000079-533xlisc	202	21	cells	cell	NOUN
cord-000079-533xlisc	202	22	in	in	ADP
cord-000079-533xlisc	202	23	human	human	ADJ
cord-000079-533xlisc	202	24	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	202	25	[	[	X
cord-000079-533xlisc	202	26	26	26	NUM
cord-000079-533xlisc	202	27	]	]	PUNCT
cord-000079-533xlisc	202	28	.	.	PUNCT
cord-000079-533xlisc	203	1	thus	thus	ADV
cord-000079-533xlisc	203	2	,	,	PUNCT
cord-000079-533xlisc	203	3	the	the	DET
cord-000079-533xlisc	203	4	cell	cell	NOUN
cord-000079-533xlisc	203	5	populations	population	NOUN
cord-000079-533xlisc	203	6	transduced	transduce	VERB
cord-000079-533xlisc	203	7	by	by	ADP
cord-000079-533xlisc	203	8	lcmv	lcmv	PROPN
cord-000079-533xlisc	203	9	or	or	CCONJ
cord-000079-533xlisc	203	10	vsv	vsv	PROPN
cord-000079-533xlisc	203	11	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	203	12	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	203	13	vectors	vector	NOUN
cord-000079-533xlisc	203	14	showed	show	VERB
cord-000079-533xlisc	203	15	features	feature	NOUN
cord-000079-533xlisc	203	16	of	of	ADP
cord-000079-533xlisc	203	17	cancer	cancer	NOUN
cord-000079-533xlisc	203	18	stem	stem	NOUN
cord-000079-533xlisc	203	19	-	-	PUNCT
cord-000079-533xlisc	203	20	like	like	ADJ
cord-000079-533xlisc	203	21	cells	cell	NOUN
cord-000079-533xlisc	203	22	which	which	PRON
cord-000079-533xlisc	203	23	might	might	AUX
cord-000079-533xlisc	203	24	be	be	AUX
cord-000079-533xlisc	203	25	an	an	DET
cord-000079-533xlisc	203	26	important	important	ADJ
cord-000079-533xlisc	203	27	target	target	NOUN
cord-000079-533xlisc	203	28	for	for	ADP
cord-000079-533xlisc	203	29	therapy	therapy	NOUN
cord-000079-533xlisc	203	30	.	.	PUNCT
cord-000079-533xlisc	204	1	in	in	ADP
cord-000079-533xlisc	204	2	a	a	DET
cord-000079-533xlisc	204	3	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	204	4	approach	approach	NOUN
cord-000079-533xlisc	204	5	using	use	VERB
cord-000079-533xlisc	204	6	the	the	DET
cord-000079-533xlisc	204	7	suicide	suicide	NOUN
cord-000079-533xlisc	204	8	gene	gene	NOUN
cord-000079-533xlisc	204	9	hsv-1	hsv-1	NOUN
cord-000079-533xlisc	204	10	-	-	PUNCT
cord-000079-533xlisc	204	11	tk	tk	PROPN
cord-000079-533xlisc	204	12	fused	fuse	VERB
cord-000079-533xlisc	204	13	to	to	ADP
cord-000079-533xlisc	204	14	egfp	egfp	NOUN
cord-000079-533xlisc	204	15	,	,	PUNCT
cord-000079-533xlisc	204	16	we	we	PRON
cord-000079-533xlisc	204	17	demonstrated	demonstrate	VERB
cord-000079-533xlisc	204	18	a	a	DET
cord-000079-533xlisc	204	19	highly	highly	ADV
cord-000079-533xlisc	204	20	significant	significant	ADJ
cord-000079-533xlisc	204	21	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	204	22	effect	effect	NOUN
cord-000079-533xlisc	204	23	for	for	ADP
cord-000079-533xlisc	204	24	both	both	DET
cord-000079-533xlisc	204	25	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	204	26	vectors	vector	NOUN
cord-000079-533xlisc	204	27	compared	compare	VERB
cord-000079-533xlisc	204	28	to	to	ADP
cord-000079-533xlisc	204	29	control	control	NOUN
cord-000079-533xlisc	204	30	groups	group	NOUN
cord-000079-533xlisc	204	31	.	.	PUNCT
cord-000079-533xlisc	205	1	using	use	VERB
cord-000079-533xlisc	205	2	mri	mri	NOUN
cord-000079-533xlisc	205	3	to	to	PART
cord-000079-533xlisc	205	4	follow	follow	VERB
cord-000079-533xlisc	205	5	tumor	tumor	NOUN
cord-000079-533xlisc	205	6	growth	growth	NOUN
cord-000079-533xlisc	205	7	,	,	PUNCT
cord-000079-533xlisc	205	8	we	we	PRON
cord-000079-533xlisc	205	9	detected	detect	VERB
cord-000079-533xlisc	205	10	complete	complete	ADJ
cord-000079-533xlisc	205	11	remission	remission	NOUN
cord-000079-533xlisc	205	12	in	in	ADP
cord-000079-533xlisc	205	13	7	7	NUM
cord-000079-533xlisc	205	14	out	out	ADP
cord-000079-533xlisc	205	15	of	of	ADP
cord-000079-533xlisc	205	16	8	8	NUM
cord-000079-533xlisc	205	17	animals	animal	NOUN
cord-000079-533xlisc	205	18	for	for	ADP
cord-000079-533xlisc	205	19	lcmv	lcmv	PROPN
cord-000079-533xlisc	205	20	-	-	PUNCT
cord-000079-533xlisc	205	21	gp	gp	PROPN
cord-000079-533xlisc	205	22	and	and	CCONJ
cord-000079-533xlisc	205	23	vsv	vsv	PROPN
cord-000079-533xlisc	205	24	-	-	PUNCT
cord-000079-533xlisc	205	25	g	g	NOUN
cord-000079-533xlisc	205	26	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	205	27	vectors	vector	NOUN
cord-000079-533xlisc	205	28	after	after	ADP
cord-000079-533xlisc	205	29	30	30	NUM
cord-000079-533xlisc	205	30	days	day	NOUN
cord-000079-533xlisc	205	31	of	of	ADP
cord-000079-533xlisc	205	32	ganciclovir	ganciclovir	PROPN
cord-000079-533xlisc	205	33	treatment	treatment	NOUN
cord-000079-533xlisc	205	34	.	.	PUNCT
cord-000079-533xlisc	206	1	hsv-1	hsv-1	PUNCT
cord-000079-533xlisc	206	2	-	-	PUNCT
cord-000079-533xlisc	206	3	tk	tk	PROPN
cord-000079-533xlisc	206	4	has	have	AUX
cord-000079-533xlisc	206	5	been	be	AUX
cord-000079-533xlisc	206	6	reported	report	VERB
cord-000079-533xlisc	206	7	to	to	PART
cord-000079-533xlisc	206	8	be	be	AUX
cord-000079-533xlisc	206	9	an	an	DET
cord-000079-533xlisc	206	10	effective	effective	ADJ
cord-000079-533xlisc	206	11	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	206	12	gene	gene	NOUN
cord-000079-533xlisc	206	13	in	in	ADP
cord-000079-533xlisc	206	14	previous	previous	ADJ
cord-000079-533xlisc	206	15	studies	study	NOUN
cord-000079-533xlisc	206	16	[	[	PUNCT
cord-000079-533xlisc	206	17	19	19	NUM
cord-000079-533xlisc	206	18	,	,	PUNCT
cord-000079-533xlisc	206	19	41	41	NUM
cord-000079-533xlisc	206	20	]	]	PUNCT
cord-000079-533xlisc	206	21	.	.	PUNCT
cord-000079-533xlisc	207	1	the	the	DET
cord-000079-533xlisc	207	2	limited	limited	ADJ
cord-000079-533xlisc	207	3	success	success	NOUN
cord-000079-533xlisc	207	4	in	in	ADP
cord-000079-533xlisc	207	5	clinical	clinical	ADJ
cord-000079-533xlisc	207	6	studies	study	NOUN
cord-000079-533xlisc	207	7	has	have	AUX
cord-000079-533xlisc	207	8	been	be	AUX
cord-000079-533xlisc	207	9	a	a	DET
cord-000079-533xlisc	207	10	result	result	NOUN
cord-000079-533xlisc	207	11	of	of	ADP
cord-000079-533xlisc	207	12	inefficient	inefficient	ADJ
cord-000079-533xlisc	207	13	gene	gene	NOUN
cord-000079-533xlisc	207	14	delivery	delivery	NOUN
cord-000079-533xlisc	207	15	systems	system	NOUN
cord-000079-533xlisc	207	16	rather	rather	ADV
cord-000079-533xlisc	207	17	than	than	ADP
cord-000079-533xlisc	207	18	lack	lack	NOUN
cord-000079-533xlisc	207	19	of	of	ADP
cord-000079-533xlisc	207	20	efficacy	efficacy	NOUN
cord-000079-533xlisc	207	21	of	of	ADP
cord-000079-533xlisc	207	22	the	the	DET
cord-000079-533xlisc	207	23	suicide	suicide	NOUN
cord-000079-533xlisc	207	24	mechanism	mechanism	NOUN
cord-000079-533xlisc	207	25	[	[	PUNCT
cord-000079-533xlisc	207	26	11	11	NUM
cord-000079-533xlisc	207	27	]	]	PUNCT
cord-000079-533xlisc	207	28	.	.	PUNCT
cord-000079-533xlisc	208	1	however	however	ADV
cord-000079-533xlisc	208	2	,	,	PUNCT
cord-000079-533xlisc	208	3	there	there	PRON
cord-000079-533xlisc	208	4	is	be	VERB
cord-000079-533xlisc	208	5	still	still	ADV
cord-000079-533xlisc	208	6	space	space	NOUN
cord-000079-533xlisc	208	7	for	for	ADP
cord-000079-533xlisc	208	8	improvement	improvement	NOUN
cord-000079-533xlisc	208	9	of	of	ADP
cord-000079-533xlisc	208	10	the	the	DET
cord-000079-533xlisc	208	11	prodrug	prodrug	NOUN
cord-000079-533xlisc	208	12	delivery	delivery	NOUN
cord-000079-533xlisc	208	13	such	such	ADJ
cord-000079-533xlisc	208	14	as	as	ADP
cord-000079-533xlisc	208	15	application	application	NOUN
cord-000079-533xlisc	208	16	length	length	NOUN
cord-000079-533xlisc	208	17	,	,	PUNCT
cord-000079-533xlisc	208	18	treatment	treatment	NOUN
cord-000079-533xlisc	208	19	intervals	interval	NOUN
cord-000079-533xlisc	208	20	and	and	CCONJ
cord-000079-533xlisc	208	21	route	route	NOUN
cord-000079-533xlisc	208	22	of	of	ADP
cord-000079-533xlisc	208	23	delivery	delivery	NOUN
cord-000079-533xlisc	208	24	.	.	PUNCT
cord-000079-533xlisc	209	1	tai	tai	PROPN
cord-000079-533xlisc	209	2	et	et	PROPN
cord-000079-533xlisc	209	3	al	al	PROPN
cord-000079-533xlisc	209	4	.	.	PROPN
cord-000079-533xlisc	209	5	demonstrated	demonstrate	VERB
cord-000079-533xlisc	209	6	that	that	SCONJ
cord-000079-533xlisc	209	7	multiple	multiple	ADJ
cord-000079-533xlisc	209	8	cycles	cycle	NOUN
cord-000079-533xlisc	209	9	of	of	ADP
cord-000079-533xlisc	209	10	prodrug	prodrug	NOUN
cord-000079-533xlisc	209	11	application	application	NOUN
cord-000079-533xlisc	209	12	are	be	AUX
cord-000079-533xlisc	209	13	superior	superior	ADJ
cord-000079-533xlisc	209	14	over	over	ADP
cord-000079-533xlisc	209	15	one	one	NUM
cord-000079-533xlisc	209	16	cycle	cycle	NOUN
cord-000079-533xlisc	209	17	of	of	ADP
cord-000079-533xlisc	209	18	prodrug	prodrug	NOUN
cord-000079-533xlisc	209	19	[	[	PUNCT
cord-000079-533xlisc	209	20	42	42	NUM
cord-000079-533xlisc	209	21	]	]	PUNCT
cord-000079-533xlisc	209	22	.	.	PUNCT
cord-000079-533xlisc	210	1	in	in	ADP
cord-000079-533xlisc	210	2	our	our	PRON
cord-000079-533xlisc	210	3	study	study	NOUN
cord-000079-533xlisc	210	4	,	,	PUNCT
cord-000079-533xlisc	210	5	we	we	PRON
cord-000079-533xlisc	210	6	still	still	ADV
cord-000079-533xlisc	210	7	detected	detect	VERB
cord-000079-533xlisc	210	8	gfp	gfp	NOUN
cord-000079-533xlisc	210	9	-	-	PUNCT
cord-000079-533xlisc	210	10	positive	positive	ADJ
cord-000079-533xlisc	210	11	tumor	tumor	NOUN
cord-000079-533xlisc	210	12	cells	cell	NOUN
cord-000079-533xlisc	210	13	after	after	ADP
cord-000079-533xlisc	210	14	one	one	NUM
cord-000079-533xlisc	210	15	cycle	cycle	NOUN
cord-000079-533xlisc	210	16	(	(	PUNCT
cord-000079-533xlisc	210	17	30	30	NUM
cord-000079-533xlisc	210	18	days	day	NOUN
cord-000079-533xlisc	210	19	)	)	PUNCT
cord-000079-533xlisc	210	20	of	of	ADP
cord-000079-533xlisc	210	21	ganciclovir	ganciclovir	PROPN
cord-000079-533xlisc	210	22	administration	administration	PROPN
cord-000079-533xlisc	210	23	in	in	ADP
cord-000079-533xlisc	210	24	treated	treat	VERB
cord-000079-533xlisc	210	25	animals	animal	NOUN
cord-000079-533xlisc	210	26	indicating	indicate	VERB
cord-000079-533xlisc	210	27	that	that	SCONJ
cord-000079-533xlisc	210	28	application	application	NOUN
cord-000079-533xlisc	210	29	in	in	ADP
cord-000079-533xlisc	210	30	cycles	cycle	NOUN
cord-000079-533xlisc	210	31	might	might	AUX
cord-000079-533xlisc	210	32	also	also	ADV
cord-000079-533xlisc	210	33	improve	improve	VERB
cord-000079-533xlisc	210	34	the	the	DET
cord-000079-533xlisc	210	35	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	210	36	effect	effect	NOUN
cord-000079-533xlisc	210	37	in	in	ADP
cord-000079-533xlisc	210	38	this	this	DET
cord-000079-533xlisc	210	39	setting	setting	NOUN
cord-000079-533xlisc	210	40	.	.	PUNCT
cord-000079-533xlisc	211	1	further	far	ADV
cord-000079-533xlisc	211	2	,	,	PUNCT
cord-000079-533xlisc	211	3	these	these	DET
cord-000079-533xlisc	211	4	results	result	NOUN
cord-000079-533xlisc	211	5	demonstrate	demonstrate	VERB
cord-000079-533xlisc	211	6	that	that	SCONJ
cord-000079-533xlisc	211	7	vector	vector	NOUN
cord-000079-533xlisc	211	8	-	-	PUNCT
cord-000079-533xlisc	211	9	transduced	transduce	VERB
cord-000079-533xlisc	211	10	tumor	tumor	NOUN
cord-000079-533xlisc	211	11	cells	cell	NOUN
cord-000079-533xlisc	211	12	retain	retain	VERB
cord-000079-533xlisc	211	13	the	the	DET
cord-000079-533xlisc	211	14	ability	ability	NOUN
cord-000079-533xlisc	211	15	to	to	PART
cord-000079-533xlisc	211	16	invade	invade	VERB
cord-000079-533xlisc	211	17	brain	brain	NOUN
cord-000079-533xlisc	211	18	tissue	tissue	NOUN
cord-000079-533xlisc	211	19	and	and	CCONJ
cord-000079-533xlisc	211	20	migrate	migrate	VERB
cord-000079-533xlisc	211	21	even	even	ADV
cord-000079-533xlisc	211	22	to	to	ADP
cord-000079-533xlisc	211	23	distant	distant	ADJ
cord-000079-533xlisc	211	24	brain	brain	NOUN
cord-000079-533xlisc	211	25	regions	region	NOUN
cord-000079-533xlisc	211	26	.	.	PUNCT
cord-000079-533xlisc	212	1	in	in	ADP
cord-000079-533xlisc	212	2	conclusion	conclusion	NOUN
cord-000079-533xlisc	212	3	,	,	PUNCT
cord-000079-533xlisc	212	4	the	the	DET
cord-000079-533xlisc	212	5	present	present	ADJ
cord-000079-533xlisc	212	6	study	study	NOUN
cord-000079-533xlisc	212	7	demonstrates	demonstrate	VERB
cord-000079-533xlisc	212	8	an	an	DET
cord-000079-533xlisc	212	9	efficient	efficient	ADJ
cord-000079-533xlisc	212	10	transduction	transduction	NOUN
cord-000079-533xlisc	212	11	and	and	CCONJ
cord-000079-533xlisc	212	12	therapy	therapy	NOUN
cord-000079-533xlisc	212	13	of	of	ADP
cord-000079-533xlisc	212	14	experimental	experimental	ADJ
cord-000079-533xlisc	212	15	human	human	ADJ
cord-000079-533xlisc	212	16	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	212	17	by	by	ADP
cord-000079-533xlisc	212	18	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	212	19	vectors	vector	NOUN
cord-000079-533xlisc	212	20	.	.	PUNCT
cord-000079-533xlisc	213	1	the	the	DET
cord-000079-533xlisc	213	2	inefficient	inefficient	ADJ
cord-000079-533xlisc	213	3	gene	gene	NOUN
cord-000079-533xlisc	213	4	transfer	transfer	NOUN
cord-000079-533xlisc	213	5	by	by	ADP
cord-000079-533xlisc	213	6	gammaretroviral	gammaretroviral	ADJ
cord-000079-533xlisc	213	7	vectors	vector	NOUN
cord-000079-533xlisc	213	8	is	be	AUX
cord-000079-533xlisc	213	9	in	in	ADP
cord-000079-533xlisc	213	10	line	line	NOUN
cord-000079-533xlisc	213	11	with	with	ADP
cord-000079-533xlisc	213	12	the	the	DET
cord-000079-533xlisc	213	13	results	result	NOUN
cord-000079-533xlisc	213	14	obtained	obtain	VERB
cord-000079-533xlisc	213	15	in	in	ADP
cord-000079-533xlisc	213	16	clinical	clinical	ADJ
cord-000079-533xlisc	213	17	trials	trial	NOUN
cord-000079-533xlisc	213	18	and	and	CCONJ
cord-000079-533xlisc	213	19	thus	thus	ADV
cord-000079-533xlisc	213	20	confirms	confirm	VERB
cord-000079-533xlisc	213	21	the	the	DET
cord-000079-533xlisc	213	22	high	high	ADJ
cord-000079-533xlisc	213	23	relevance	relevance	NOUN
cord-000079-533xlisc	213	24	of	of	ADP
cord-000079-533xlisc	213	25	the	the	DET
cord-000079-533xlisc	213	26	spheroid	spheroid	NOUN
cord-000079-533xlisc	213	27	-	-	PUNCT
cord-000079-533xlisc	213	28	based	base	VERB
cord-000079-533xlisc	213	29	glioma	glioma	NOUN
cord-000079-533xlisc	213	30	animal	animal	NOUN
cord-000079-533xlisc	213	31	model	model	NOUN
cord-000079-533xlisc	213	32	for	for	ADP
cord-000079-533xlisc	213	33	translational	translational	ADJ
cord-000079-533xlisc	213	34	research	research	NOUN
cord-000079-533xlisc	213	35	.	.	PUNCT
cord-000079-533xlisc	214	1	radiotherapy	radiotherapy	NOUN
cord-000079-533xlisc	214	2	plus	plus	CCONJ
cord-000079-533xlisc	214	3	concomitant	concomitant	NOUN
cord-000079-533xlisc	214	4	and	and	CCONJ
cord-000079-533xlisc	214	5	adjuvant	adjuvant	ADJ
cord-000079-533xlisc	214	6	temozolomide	temozolomide	NOUN
cord-000079-533xlisc	214	7	for	for	ADP
cord-000079-533xlisc	214	8	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	214	9	expression	expression	NOUN
cord-000079-533xlisc	214	10	of	of	ADP
cord-000079-533xlisc	214	11	extracellular	extracellular	ADJ
cord-000079-533xlisc	214	12	matrix	matrix	NOUN
cord-000079-533xlisc	214	13	components	component	NOUN
cord-000079-533xlisc	214	14	in	in	ADP
cord-000079-533xlisc	214	15	a	a	DET
cord-000079-533xlisc	214	16	highly	highly	ADV
cord-000079-533xlisc	214	17	infiltrative	infiltrative	ADJ
cord-000079-533xlisc	214	18	in	in	ADP
cord-000079-533xlisc	214	19	vivo	vivo	ADJ
cord-000079-533xlisc	214	20	glioma	glioma	NOUN
cord-000079-533xlisc	214	21	model	model	NOUN
cord-000079-533xlisc	214	22	angiogenesis	angiogenesis	ADJ
cord-000079-533xlisc	214	23	-	-	PUNCT
cord-000079-533xlisc	214	24	independent	independent	ADJ
cord-000079-533xlisc	214	25	tumor	tumor	NOUN
cord-000079-533xlisc	214	26	growth	growth	NOUN
cord-000079-533xlisc	214	27	mediated	mediate	VERB
cord-000079-533xlisc	214	28	by	by	ADP
cord-000079-533xlisc	214	29	stem	stem	NOUN
cord-000079-533xlisc	214	30	-	-	PUNCT
cord-000079-533xlisc	214	31	like	like	ADJ
cord-000079-533xlisc	214	32	cancer	cancer	NOUN
cord-000079-533xlisc	214	33	cells	cell	NOUN
cord-000079-533xlisc	214	34	oncolytic	oncolytic	ADJ
cord-000079-533xlisc	214	35	herpes	herpe	NOUN
cord-000079-533xlisc	214	36	simplex	simplex	ADJ
cord-000079-533xlisc	214	37	virus	virus	PROPN
cord-000079-533xlisc	214	38	type-1	type-1	NOUN
cord-000079-533xlisc	214	39	therapy	therapy	NOUN
cord-000079-533xlisc	214	40	in	in	ADP
cord-000079-533xlisc	214	41	a	a	DET
cord-000079-533xlisc	214	42	highly	highly	ADV
cord-000079-533xlisc	214	43	infiltrative	infiltrative	ADJ
cord-000079-533xlisc	214	44	animal	animal	NOUN
cord-000079-533xlisc	214	45	model	model	NOUN
cord-000079-533xlisc	214	46	of	of	ADP
cord-000079-533xlisc	214	47	human	human	ADJ
cord-000079-533xlisc	214	48	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	214	49	attenuated	attenuate	VERB
cord-000079-533xlisc	214	50	multi	multi	ADJ
cord-000079-533xlisc	214	51	-	-	ADJ
cord-000079-533xlisc	214	52	mutated	mutate	VERB
cord-000079-533xlisc	214	53	herpes	herpe	NOUN
cord-000079-533xlisc	214	54	simplex	simplex	ADJ
cord-000079-533xlisc	214	55	virus-1	virus-1	ADJ
cord-000079-533xlisc	214	56	for	for	ADP
cord-000079-533xlisc	214	57	the	the	DET
cord-000079-533xlisc	214	58	treatment	treatment	NOUN
cord-000079-533xlisc	214	59	of	of	ADP
cord-000079-533xlisc	214	60	malignant	malignant	ADJ
cord-000079-533xlisc	214	61	gliomas	glioma	NOUN
cord-000079-533xlisc	214	62	phase	phase	NOUN
cord-000079-533xlisc	214	63	ib	ib	PROPN
cord-000079-533xlisc	214	64	trial	trial	NOUN
cord-000079-533xlisc	214	65	of	of	ADP
cord-000079-533xlisc	214	66	mutant	mutant	ADJ
cord-000079-533xlisc	214	67	herpes	herpe	NOUN
cord-000079-533xlisc	214	68	simplex	simplex	ADJ
cord-000079-533xlisc	214	69	virus	virus	NOUN
cord-000079-533xlisc	214	70	g207	g207	PROPN
cord-000079-533xlisc	214	71	inoculated	inoculate	VERB
cord-000079-533xlisc	214	72	pre	pre	ADJ
cord-000079-533xlisc	214	73	-	-	ADJ
cord-000079-533xlisc	214	74	and	and	CCONJ
cord-000079-533xlisc	214	75	post	post	ADJ
cord-000079-533xlisc	214	76	-	-	ADJ
cord-000079-533xlisc	214	77	tumor	tumor	ADJ
cord-000079-533xlisc	214	78	resection	resection	NOUN
cord-000079-533xlisc	214	79	for	for	ADP
cord-000079-533xlisc	214	80	recurrent	recurrent	ADJ
cord-000079-533xlisc	214	81	gbm	gbm	PROPN
cord-000079-533xlisc	214	82	eradication	eradication	NOUN
cord-000079-533xlisc	214	83	of	of	ADP
cord-000079-533xlisc	214	84	rat	rat	NOUN
cord-000079-533xlisc	214	85	malignant	malignant	ADJ
cord-000079-533xlisc	214	86	gliomas	glioma	NOUN
cord-000079-533xlisc	214	87	by	by	ADP
cord-000079-533xlisc	214	88	retroviral	retroviral	ADV
cord-000079-533xlisc	214	89	-	-	PUNCT
cord-000079-533xlisc	214	90	mediated	mediate	VERB
cord-000079-533xlisc	214	91	,	,	PUNCT
cord-000079-533xlisc	214	92	in	in	ADP
cord-000079-533xlisc	214	93	vivo	vivo	ADJ
cord-000079-533xlisc	214	94	delivery	delivery	NOUN
cord-000079-533xlisc	214	95	of	of	ADP
cord-000079-533xlisc	214	96	the	the	DET
cord-000079-533xlisc	214	97	interleukin	interleukin	NOUN
cord-000079-533xlisc	214	98	4	4	NUM
cord-000079-533xlisc	214	99	gene	gene	NOUN
cord-000079-533xlisc	214	100	inhibition	inhibition	NOUN
cord-000079-533xlisc	214	101	of	of	ADP
cord-000079-533xlisc	214	102	glioma	glioma	NOUN
cord-000079-533xlisc	214	103	angiogenesis	angiogenesis	NOUN
cord-000079-533xlisc	214	104	and	and	CCONJ
cord-000079-533xlisc	214	105	growth	growth	NOUN
cord-000079-533xlisc	214	106	in	in	ADP
cord-000079-533xlisc	214	107	vivo	vivo	NOUN
cord-000079-533xlisc	214	108	by	by	ADP
cord-000079-533xlisc	214	109	systemic	systemic	ADJ
cord-000079-533xlisc	214	110	treatment	treatment	NOUN
cord-000079-533xlisc	214	111	with	with	ADP
cord-000079-533xlisc	214	112	a	a	DET
cord-000079-533xlisc	214	113	monoclonal	monoclonal	NOUN
cord-000079-533xlisc	214	114	antibody	antibody	NOUN
cord-000079-533xlisc	214	115	against	against	ADP
cord-000079-533xlisc	214	116	vascular	vascular	ADJ
cord-000079-533xlisc	214	117	endothelial	endothelial	ADJ
cord-000079-533xlisc	214	118	growth	growth	NOUN
cord-000079-533xlisc	214	119	factor	factor	NOUN
cord-000079-533xlisc	214	120	receptor-2	receptor-2	NOUN
cord-000079-533xlisc	214	121	eradication	eradication	NOUN
cord-000079-533xlisc	214	122	of	of	ADP
cord-000079-533xlisc	214	123	murine	murine	NOUN
cord-000079-533xlisc	214	124	brain	brain	NOUN
cord-000079-533xlisc	214	125	tumors	tumor	NOUN
cord-000079-533xlisc	214	126	by	by	ADP
cord-000079-533xlisc	214	127	direct	direct	ADJ
cord-000079-533xlisc	214	128	inoculation	inoculation	NOUN
cord-000079-533xlisc	214	129	of	of	ADP
cord-000079-533xlisc	214	130	concentrated	concentrated	ADJ
cord-000079-533xlisc	214	131	high	high	ADJ
cord-000079-533xlisc	214	132	titer	titer	NOUN
cord-000079-533xlisc	214	133	-	-	PUNCT
cord-000079-533xlisc	214	134	recombinant	recombinant	ADJ
cord-000079-533xlisc	214	135	retrovirus	retrovirus	NOUN
cord-000079-533xlisc	214	136	harboring	harbor	VERB
cord-000079-533xlisc	214	137	the	the	DET
cord-000079-533xlisc	214	138	herpes	herpe	NOUN
cord-000079-533xlisc	214	139	simplex	simplex	ADJ
cord-000079-533xlisc	214	140	virus	virus	NOUN
cord-000079-533xlisc	214	141	thymidine	thymidine	NOUN
cord-000079-533xlisc	214	142	kinase	kinase	NOUN
cord-000079-533xlisc	214	143	gene	gene	NOUN
cord-000079-533xlisc	214	144	highly	highly	ADV
cord-000079-533xlisc	214	145	efficient	efficient	ADJ
cord-000079-533xlisc	214	146	and	and	CCONJ
cord-000079-533xlisc	214	147	tumorrestricted	tumorrestricted	ADJ
cord-000079-533xlisc	214	148	gene	gene	NOUN
cord-000079-533xlisc	214	149	transfer	transfer	NOUN
cord-000079-533xlisc	214	150	to	to	ADP
cord-000079-533xlisc	214	151	malignant	malignant	ADJ
cord-000079-533xlisc	214	152	gliomas	glioma	NOUN
cord-000079-533xlisc	214	153	by	by	ADP
cord-000079-533xlisc	214	154	replication	replication	NOUN
cord-000079-533xlisc	214	155	-	-	PUNCT
cord-000079-533xlisc	214	156	competent	competent	ADJ
cord-000079-533xlisc	214	157	retroviral	retroviral	ADJ
cord-000079-533xlisc	214	158	vectors	vector	NOUN
cord-000079-533xlisc	214	159	clinical	clinical	ADJ
cord-000079-533xlisc	214	160	trials	trial	NOUN
cord-000079-533xlisc	214	161	with	with	ADP
cord-000079-533xlisc	214	162	retrovirus	retrovirus	NOUN
cord-000079-533xlisc	214	163	mediated	mediate	VERB
cord-000079-533xlisc	214	164	gene	gene	NOUN
cord-000079-533xlisc	214	165	therapywhat	therapywhat	PRON
cord-000079-533xlisc	214	166	have	have	AUX
cord-000079-533xlisc	214	167	we	we	PRON
cord-000079-533xlisc	214	168	learned	learn	VERB
cord-000079-533xlisc	214	169	?	?	PUNCT
cord-000079-533xlisc	215	1	a	a	DET
cord-000079-533xlisc	215	2	phase	phase	NOUN
cord-000079-533xlisc	215	3	iii	iii	NUM
cord-000079-533xlisc	215	4	clinical	clinical	ADJ
cord-000079-533xlisc	215	5	evaluation	evaluation	NOUN
cord-000079-533xlisc	215	6	of	of	ADP
cord-000079-533xlisc	215	7	herpes	herpe	NOUN
cord-000079-533xlisc	215	8	simplex	simplex	ADJ
cord-000079-533xlisc	215	9	virus	virus	PROPN
cord-000079-533xlisc	215	10	type	type	NOUN
cord-000079-533xlisc	215	11	1	1	NUM
cord-000079-533xlisc	215	12	thymidine	thymidine	NOUN
cord-000079-533xlisc	215	13	kinase	kinase	NOUN
cord-000079-533xlisc	215	14	and	and	CCONJ
cord-000079-533xlisc	215	15	ganciclovir	ganciclovir	PROPN
cord-000079-533xlisc	215	16	gene	gene	NOUN
cord-000079-533xlisc	215	17	therapy	therapy	NOUN
cord-000079-533xlisc	215	18	as	as	ADP
cord-000079-533xlisc	215	19	an	an	DET
cord-000079-533xlisc	215	20	adjuvant	adjuvant	NOUN
cord-000079-533xlisc	215	21	to	to	ADP
cord-000079-533xlisc	215	22	surgical	surgical	ADJ
cord-000079-533xlisc	215	23	resection	resection	NOUN
cord-000079-533xlisc	215	24	and	and	CCONJ
cord-000079-533xlisc	215	25	radiation	radiation	NOUN
cord-000079-533xlisc	215	26	in	in	ADP
cord-000079-533xlisc	215	27	adults	adult	NOUN
cord-000079-533xlisc	215	28	with	with	ADP
cord-000079-533xlisc	215	29	previously	previously	ADV
cord-000079-533xlisc	215	30	untreated	untreated	ADJ
cord-000079-533xlisc	215	31	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	215	32	multiforme	multiforme	ADJ
cord-000079-533xlisc	215	33	thymidine	thymidine	NOUN
cord-000079-533xlisc	215	34	kinase	kinase	NOUN
cord-000079-533xlisc	215	35	gene	gene	NOUN
cord-000079-533xlisc	215	36	therapy	therapy	NOUN
cord-000079-533xlisc	215	37	for	for	ADP
cord-000079-533xlisc	215	38	human	human	ADJ
cord-000079-533xlisc	215	39	malignant	malignant	ADJ
cord-000079-533xlisc	215	40	glioma	glioma	NOUN
cord-000079-533xlisc	215	41	,	,	PUNCT
cord-000079-533xlisc	215	42	using	use	VERB
cord-000079-533xlisc	215	43	replication	replication	NOUN
cord-000079-533xlisc	215	44	-	-	PUNCT
cord-000079-533xlisc	215	45	deficient	deficient	ADJ
cord-000079-533xlisc	215	46	retroviruses	retrovirus	NOUN
cord-000079-533xlisc	215	47	or	or	CCONJ
cord-000079-533xlisc	215	48	adenoviruses	adenovirus	NOUN
cord-000079-533xlisc	215	49	oncoretrovirus	oncoretrovirus	PROPN
cord-000079-533xlisc	215	50	and	and	CCONJ
cord-000079-533xlisc	215	51	lentivirus	lentivirus	NOUN
cord-000079-533xlisc	215	52	vectors	vector	NOUN
cord-000079-533xlisc	215	53	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	215	54	with	with	ADP
cord-000079-533xlisc	215	55	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	215	56	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	215	57	virus	virus	NOUN
cord-000079-533xlisc	215	58	glycoprotein	glycoprotein	NOUN
cord-000079-533xlisc	215	59	:	:	PUNCT
cord-000079-533xlisc	215	60	generation	generation	NOUN
cord-000079-533xlisc	215	61	,	,	PUNCT
cord-000079-533xlisc	215	62	concentration	concentration	NOUN
cord-000079-533xlisc	215	63	,	,	PUNCT
cord-000079-533xlisc	215	64	and	and	CCONJ
cord-000079-533xlisc	215	65	broad	broad	ADJ
cord-000079-533xlisc	215	66	host	host	NOUN
cord-000079-533xlisc	215	67	range	range	VERB
cord-000079-533xlisc	215	68	retroviral	retroviral	ADJ
cord-000079-533xlisc	215	69	vectors	vector	NOUN
cord-000079-533xlisc	215	70	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	215	71	with	with	ADP
cord-000079-533xlisc	215	72	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	215	73	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	215	74	virus	virus	NOUN
cord-000079-533xlisc	215	75	recombinant	recombinant	ADJ
cord-000079-533xlisc	215	76	expression	expression	NOUN
cord-000079-533xlisc	215	77	of	of	ADP
cord-000079-533xlisc	215	78	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	215	79	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	215	80	virus	virus	NOUN
cord-000079-533xlisc	215	81	strain	strain	VERB
cord-000079-533xlisc	215	82	we	we	PRON
cord-000079-533xlisc	215	83	glycoproteins	glycoprotein	NOUN
cord-000079-533xlisc	215	84	:	:	PUNCT
cord-000079-533xlisc	215	85	a	a	DET
cord-000079-533xlisc	215	86	single	single	ADJ
cord-000079-533xlisc	215	87	amino	amino	NOUN
cord-000079-533xlisc	215	88	acid	acid	NOUN
cord-000079-533xlisc	215	89	makes	make	VERB
cord-000079-533xlisc	215	90	the	the	DET
cord-000079-533xlisc	215	91	difference	difference	NOUN
cord-000079-533xlisc	215	92	a	a	DET
cord-000079-533xlisc	215	93	retroviral	retroviral	ADJ
cord-000079-533xlisc	215	94	packaging	packaging	NOUN
cord-000079-533xlisc	215	95	cell	cell	NOUN
cord-000079-533xlisc	215	96	line	line	NOUN
cord-000079-533xlisc	215	97	for	for	ADP
cord-000079-533xlisc	215	98	pseudotype	pseudotype	ADJ
cord-000079-533xlisc	215	99	vectors	vector	NOUN
cord-000079-533xlisc	215	100	based	base	VERB
cord-000079-533xlisc	215	101	on	on	ADP
cord-000079-533xlisc	215	102	glioma	glioma	NOUN
cord-000079-533xlisc	215	103	-	-	PUNCT
cord-000079-533xlisc	215	104	infiltrating	infiltrate	VERB
cord-000079-533xlisc	215	105	progenitor	progenitor	NOUN
cord-000079-533xlisc	215	106	cells	cell	VERB
cord-000079-533xlisc	215	107	selective	selective	ADJ
cord-000079-533xlisc	215	108	transduction	transduction	NOUN
cord-000079-533xlisc	215	109	of	of	ADP
cord-000079-533xlisc	215	110	malignant	malignant	ADJ
cord-000079-533xlisc	215	111	glioma	glioma	NOUN
cord-000079-533xlisc	215	112	by	by	ADP
cord-000079-533xlisc	215	113	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	215	114	vectors	vector	NOUN
cord-000079-533xlisc	215	115	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	215	116	with	with	ADP
cord-000079-533xlisc	215	117	lymphocytic	lymphocytic	ADJ
cord-000079-533xlisc	215	118	choriomeningitis	choriomeningitis	NOUN
cord-000079-533xlisc	215	119	virus	virus	NOUN
cord-000079-533xlisc	215	120	glycoproteins	glycoprotein	VERB
cord-000079-533xlisc	215	121	normal	normal	ADJ
cord-000079-533xlisc	215	122	brain	brain	NOUN
cord-000079-533xlisc	215	123	cells	cell	NOUN
cord-000079-533xlisc	215	124	contribute	contribute	VERB
cord-000079-533xlisc	215	125	to	to	ADP
cord-000079-533xlisc	215	126	the	the	DET
cord-000079-533xlisc	215	127	bystander	bystander	NOUN
cord-000079-533xlisc	215	128	effect	effect	NOUN
cord-000079-533xlisc	215	129	in	in	ADP
cord-000079-533xlisc	215	130	suicide	suicide	NOUN
cord-000079-533xlisc	215	131	gene	gene	NOUN
cord-000079-533xlisc	215	132	therapy	therapy	NOUN
cord-000079-533xlisc	215	133	of	of	ADP
cord-000079-533xlisc	215	134	malignant	malignant	ADJ
cord-000079-533xlisc	215	135	glioma	glioma	NOUN
cord-000079-533xlisc	215	136	multicellular	multicellular	ADJ
cord-000079-533xlisc	215	137	tumor	tumor	NOUN
cord-000079-533xlisc	215	138	spheroids	spheroid	NOUN
cord-000079-533xlisc	215	139	from	from	ADP
cord-000079-533xlisc	215	140	human	human	ADJ
cord-000079-533xlisc	215	141	gliomas	glioma	NOUN
cord-000079-533xlisc	215	142	maintained	maintain	VERB
cord-000079-533xlisc	215	143	in	in	ADP
cord-000079-533xlisc	215	144	organ	organ	NOUN
cord-000079-533xlisc	215	145	culture	culture	NOUN
cord-000079-533xlisc	215	146	in	in	ADP
cord-000079-533xlisc	215	147	vivo	vivo	ADJ
cord-000079-533xlisc	215	148	gene	gene	NOUN
cord-000079-533xlisc	215	149	delivery	delivery	NOUN
cord-000079-533xlisc	215	150	and	and	CCONJ
cord-000079-533xlisc	215	151	stable	stable	ADJ
cord-000079-533xlisc	215	152	transduction	transduction	NOUN
cord-000079-533xlisc	215	153	of	of	ADP
cord-000079-533xlisc	215	154	nondividing	nondivide	VERB
cord-000079-533xlisc	215	155	cells	cell	NOUN
cord-000079-533xlisc	215	156	by	by	ADP
cord-000079-533xlisc	215	157	a	a	DET
cord-000079-533xlisc	215	158	lentiviral	lentiviral	ADJ
cord-000079-533xlisc	215	159	vector	vector	NOUN
cord-000079-533xlisc	215	160	context	context	NOUN
cord-000079-533xlisc	215	161	dependence	dependence	NOUN
cord-000079-533xlisc	215	162	of	of	ADP
cord-000079-533xlisc	215	163	different	different	ADJ
cord-000079-533xlisc	215	164	modules	module	NOUN
cord-000079-533xlisc	215	165	for	for	ADP
cord-000079-533xlisc	215	166	posttranscriptional	posttranscriptional	ADJ
cord-000079-533xlisc	215	167	enhancement	enhancement	NOUN
cord-000079-533xlisc	215	168	of	of	ADP
cord-000079-533xlisc	215	169	gene	gene	NOUN
cord-000079-533xlisc	215	170	expression	expression	NOUN
cord-000079-533xlisc	215	171	from	from	ADP
cord-000079-533xlisc	215	172	retroviral	retroviral	ADJ
cord-000079-533xlisc	215	173	vectors	vector	NOUN
cord-000079-533xlisc	215	174	a	a	DET
cord-000079-533xlisc	215	175	general	general	ADJ
cord-000079-533xlisc	215	176	method	method	NOUN
cord-000079-533xlisc	215	177	for	for	ADP
cord-000079-533xlisc	215	178	the	the	DET
cord-000079-533xlisc	215	179	generation	generation	NOUN
cord-000079-533xlisc	215	180	of	of	ADP
cord-000079-533xlisc	215	181	high	high	ADJ
cord-000079-533xlisc	215	182	-	-	PUNCT
cord-000079-533xlisc	215	183	titer	titer	NOUN
cord-000079-533xlisc	215	184	,	,	PUNCT
cord-000079-533xlisc	215	185	pantropic	pantropic	ADJ
cord-000079-533xlisc	215	186	retroviral	retroviral	ADJ
cord-000079-533xlisc	215	187	vectors	vector	NOUN
cord-000079-533xlisc	215	188	:	:	PUNCT
cord-000079-533xlisc	215	189	highly	highly	ADV
cord-000079-533xlisc	215	190	efficient	efficient	ADJ
cord-000079-533xlisc	215	191	infection	infection	NOUN
cord-000079-533xlisc	215	192	of	of	ADP
cord-000079-533xlisc	215	193	primary	primary	ADJ
cord-000079-533xlisc	215	194	hepatocytes	hepatocyte	NOUN
cord-000079-533xlisc	215	195	retroviral	retroviral	ADJ
cord-000079-533xlisc	215	196	vectors	vector	NOUN
cord-000079-533xlisc	215	197	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	215	198	with	with	ADP
cord-000079-533xlisc	215	199	severe	severe	ADJ
cord-000079-533xlisc	215	200	acute	acute	ADJ
cord-000079-533xlisc	215	201	respiratory	respiratory	ADJ
cord-000079-533xlisc	215	202	syndrome	syndrome	NOUN
cord-000079-533xlisc	215	203	coronavirus	coronavirus	PROPN
cord-000079-533xlisc	215	204	s	s	PART
cord-000079-533xlisc	215	205	protein	protein	NOUN
cord-000079-533xlisc	215	206	widespread	widespread	ADJ
cord-000079-533xlisc	215	207	dispersion	dispersion	NOUN
cord-000079-533xlisc	215	208	of	of	ADP
cord-000079-533xlisc	215	209	adeno	adeno	NOUN
cord-000079-533xlisc	215	210	-	-	PUNCT
cord-000079-533xlisc	215	211	associated	associate	VERB
cord-000079-533xlisc	215	212	virus	virus	PROPN
cord-000079-533xlisc	215	213	serotype	serotype	NOUN
cord-000079-533xlisc	215	214	1	1	NUM
cord-000079-533xlisc	215	215	and	and	CCONJ
cord-000079-533xlisc	215	216	adenoassociated	adenoassociated	ADJ
cord-000079-533xlisc	215	217	virus	virus	NOUN
cord-000079-533xlisc	215	218	serotype	serotype	VERB
cord-000079-533xlisc	215	219	6	6	NUM
cord-000079-533xlisc	215	220	vectors	vector	NOUN
cord-000079-533xlisc	215	221	in	in	ADP
cord-000079-533xlisc	215	222	the	the	DET
cord-000079-533xlisc	215	223	rat	rat	NOUN
cord-000079-533xlisc	215	224	central	central	ADJ
cord-000079-533xlisc	215	225	nervous	nervous	ADJ
cord-000079-533xlisc	215	226	system	system	NOUN
cord-000079-533xlisc	215	227	and	and	CCONJ
cord-000079-533xlisc	215	228	in	in	ADP
cord-000079-533xlisc	215	229	human	human	ADJ
cord-000079-533xlisc	215	230	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	215	231	multiforme	multiforme	ADJ
cord-000079-533xlisc	215	232	xenografts	xenograft	NOUN
cord-000079-533xlisc	215	233	tumor	tumor	NOUN
cord-000079-533xlisc	215	234	stem	stem	NOUN
cord-000079-533xlisc	215	235	cells	cell	NOUN
cord-000079-533xlisc	215	236	derived	derive	VERB
cord-000079-533xlisc	215	237	from	from	ADP
cord-000079-533xlisc	215	238	glioblastomas	glioblastomas	PROPN
cord-000079-533xlisc	215	239	cultured	culture	VERB
cord-000079-533xlisc	215	240	in	in	ADP
cord-000079-533xlisc	215	241	bfgf	bfgf	PROPN
cord-000079-533xlisc	215	242	and	and	CCONJ
cord-000079-533xlisc	215	243	egf	egf	NOUN
cord-000079-533xlisc	215	244	more	more	ADV
cord-000079-533xlisc	215	245	closely	closely	ADV
cord-000079-533xlisc	215	246	mirror	mirror	VERB
cord-000079-533xlisc	215	247	the	the	DET
cord-000079-533xlisc	215	248	phenotype	phenotype	NOUN
cord-000079-533xlisc	215	249	and	and	CCONJ
cord-000079-533xlisc	215	250	genotype	genotype	NOUN
cord-000079-533xlisc	215	251	of	of	ADP
cord-000079-533xlisc	215	252	primary	primary	ADJ
cord-000079-533xlisc	215	253	tumors	tumor	NOUN
cord-000079-533xlisc	215	254	than	than	SCONJ
cord-000079-533xlisc	215	255	do	do	AUX
cord-000079-533xlisc	215	256	serum	serum	NOUN
cord-000079-533xlisc	215	257	-	-	PUNCT
cord-000079-533xlisc	215	258	cultured	cultured	ADJ
cord-000079-533xlisc	215	259	cell	cell	NOUN
cord-000079-533xlisc	215	260	lines	line	NOUN
cord-000079-533xlisc	215	261	vesicular	vesicular	ADJ
cord-000079-533xlisc	215	262	stomatitis	stomatitis	PROPN
cord-000079-533xlisc	215	263	virus	virus	NOUN
cord-000079-533xlisc	215	264	g	g	PROPN
cord-000079-533xlisc	215	265	pseudotyped	pseudotype	VERB
cord-000079-533xlisc	215	266	retrovector	retrovector	NOUN
cord-000079-533xlisc	215	267	mediates	mediate	VERB
cord-000079-533xlisc	215	268	effective	effective	ADJ
cord-000079-533xlisc	215	269	in	in	ADP
cord-000079-533xlisc	215	270	vivo	vivo	ADJ
cord-000079-533xlisc	215	271	suicide	suicide	NOUN
cord-000079-533xlisc	215	272	gene	gene	NOUN
cord-000079-533xlisc	215	273	delivery	delivery	NOUN
cord-000079-533xlisc	215	274	in	in	ADP
cord-000079-533xlisc	215	275	experimental	experimental	ADJ
cord-000079-533xlisc	215	276	brain	brain	NOUN
cord-000079-533xlisc	215	277	cancer	cancer	NOUN
cord-000079-533xlisc	215	278	convection	convection	NOUN
cord-000079-533xlisc	215	279	enhanced	enhance	VERB
cord-000079-533xlisc	215	280	drug	drug	NOUN
cord-000079-533xlisc	215	281	delivery	delivery	NOUN
cord-000079-533xlisc	215	282	of	of	ADP
cord-000079-533xlisc	215	283	novel	novel	ADJ
cord-000079-533xlisc	215	284	therapeutic	therapeutic	ADJ
cord-000079-533xlisc	215	285	agents	agent	NOUN
cord-000079-533xlisc	215	286	to	to	PART
cord-000079-533xlisc	215	287	malignant	malignant	ADJ
cord-000079-533xlisc	215	288	brain	brain	NOUN
cord-000079-533xlisc	215	289	tumors	tumor	NOUN
cord-000079-533xlisc	215	290	phosphatidylserine	phosphatidylserine	NOUN
cord-000079-533xlisc	215	291	is	be	AUX
cord-000079-533xlisc	215	292	not	not	PART
cord-000079-533xlisc	215	293	the	the	DET
cord-000079-533xlisc	215	294	cell	cell	NOUN
cord-000079-533xlisc	215	295	surface	surface	NOUN
cord-000079-533xlisc	215	296	receptor	receptor	NOUN
cord-000079-533xlisc	215	297	for	for	ADP
cord-000079-533xlisc	215	298	vesicular	vesicular	ADJ
cord-000079-533xlisc	215	299	stomatitis	stomatitis	PROPN
cord-000079-533xlisc	215	300	virus	virus	NOUN
cord-000079-533xlisc	215	301	identification	identification	NOUN
cord-000079-533xlisc	215	302	of	of	ADP
cord-000079-533xlisc	215	303	human	human	ADJ
cord-000079-533xlisc	215	304	brain	brain	NOUN
cord-000079-533xlisc	215	305	tumour	tumour	NOUN
cord-000079-533xlisc	215	306	initiating	initiate	VERB
cord-000079-533xlisc	215	307	cells	cell	NOUN
cord-000079-533xlisc	215	308	isolation	isolation	NOUN
cord-000079-533xlisc	215	309	and	and	CCONJ
cord-000079-533xlisc	215	310	characterization	characterization	NOUN
cord-000079-533xlisc	215	311	of	of	ADP
cord-000079-533xlisc	215	312	tumorigenic	tumorigenic	ADJ
cord-000079-533xlisc	215	313	,	,	PUNCT
cord-000079-533xlisc	215	314	stem	stem	NOUN
cord-000079-533xlisc	215	315	-	-	PUNCT
cord-000079-533xlisc	215	316	like	like	ADJ
cord-000079-533xlisc	215	317	neural	neural	ADJ
cord-000079-533xlisc	215	318	precursors	precursor	NOUN
cord-000079-533xlisc	215	319	from	from	ADP
cord-000079-533xlisc	215	320	human	human	ADJ
cord-000079-533xlisc	215	321	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	215	322	glioma	glioma	NOUN
cord-000079-533xlisc	215	323	stem	stem	NOUN
cord-000079-533xlisc	215	324	cells	cell	NOUN
cord-000079-533xlisc	215	325	promote	promote	VERB
cord-000079-533xlisc	215	326	radioresistance	radioresistance	NOUN
cord-000079-533xlisc	215	327	by	by	ADP
cord-000079-533xlisc	215	328	preferential	preferential	ADJ
cord-000079-533xlisc	215	329	activation	activation	NOUN
cord-000079-533xlisc	215	330	of	of	ADP
cord-000079-533xlisc	215	331	the	the	DET
cord-000079-533xlisc	215	332	dna	dna	NOUN
cord-000079-533xlisc	215	333	damage	damage	NOUN
cord-000079-533xlisc	215	334	response	response	NOUN
cord-000079-533xlisc	215	335	tumor	tumor	NOUN
cord-000079-533xlisc	215	336	growth	growth	NOUN
cord-000079-533xlisc	215	337	need	need	AUX
cord-000079-533xlisc	215	338	not	not	PART
cord-000079-533xlisc	215	339	be	be	AUX
cord-000079-533xlisc	215	340	driven	drive	VERB
cord-000079-533xlisc	215	341	by	by	ADP
cord-000079-533xlisc	215	342	rare	rare	ADJ
cord-000079-533xlisc	215	343	cancer	cancer	NOUN
cord-000079-533xlisc	215	344	stem	stem	NOUN
cord-000079-533xlisc	215	345	cells	cell	NOUN
cord-000079-533xlisc	215	346	efficient	efficient	ADJ
cord-000079-533xlisc	215	347	tumour	tumour	NOUN
cord-000079-533xlisc	215	348	formation	formation	NOUN
cord-000079-533xlisc	215	349	by	by	ADP
cord-000079-533xlisc	215	350	single	single	ADJ
cord-000079-533xlisc	215	351	human	human	ADJ
cord-000079-533xlisc	215	352	melanoma	melanoma	NOUN
cord-000079-533xlisc	215	353	cells	cell	NOUN
cord-000079-533xlisc	215	354	identification	identification	NOUN
cord-000079-533xlisc	215	355	of	of	ADP
cord-000079-533xlisc	215	356	a	a	DET
cord-000079-533xlisc	215	357	cancer	cancer	NOUN
cord-000079-533xlisc	215	358	stem	stem	NOUN
cord-000079-533xlisc	215	359	cell	cell	NOUN
cord-000079-533xlisc	215	360	in	in	ADP
cord-000079-533xlisc	215	361	human	human	ADJ
cord-000079-533xlisc	215	362	brain	brain	NOUN
cord-000079-533xlisc	215	363	tumors	tumor	NOUN
cord-000079-533xlisc	215	364	cd133(+	cd133(+	PROPN
cord-000079-533xlisc	215	365	)	)	PUNCT
cord-000079-533xlisc	215	366	and	and	CCONJ
cord-000079-533xlisc	215	367	cd133(2	cd133(2	PROPN
cord-000079-533xlisc	215	368	)	)	PUNCT
cord-000079-533xlisc	215	369	glioblastoma	glioblastoma	NOUN
cord-000079-533xlisc	215	370	-	-	PUNCT
cord-000079-533xlisc	215	371	derived	derive	VERB
cord-000079-533xlisc	215	372	cancer	cancer	NOUN
cord-000079-533xlisc	215	373	stem	stem	NOUN
cord-000079-533xlisc	215	374	cells	cell	NOUN
cord-000079-533xlisc	215	375	show	show	VERB
cord-000079-533xlisc	215	376	differential	differential	ADJ
cord-000079-533xlisc	215	377	growth	growth	NOUN
cord-000079-533xlisc	215	378	characteristics	characteristic	NOUN
cord-000079-533xlisc	215	379	and	and	CCONJ
cord-000079-533xlisc	215	380	molecular	molecular	ADJ
cord-000079-533xlisc	215	381	profiles	profile	NOUN
cord-000079-533xlisc	215	382	cd133	cd133	VERB
cord-000079-533xlisc	215	383	negative	negative	ADJ
cord-000079-533xlisc	215	384	glioma	glioma	NOUN
cord-000079-533xlisc	215	385	cells	cell	NOUN
cord-000079-533xlisc	215	386	form	form	VERB
cord-000079-533xlisc	215	387	tumors	tumor	NOUN
cord-000079-533xlisc	215	388	in	in	ADP
cord-000079-533xlisc	215	389	nude	nude	ADJ
cord-000079-533xlisc	215	390	rats	rat	NOUN
cord-000079-533xlisc	215	391	and	and	CCONJ
cord-000079-533xlisc	215	392	give	give	VERB
cord-000079-533xlisc	215	393	rise	rise	NOUN
cord-000079-533xlisc	215	394	to	to	ADP
cord-000079-533xlisc	215	395	cd133	cd133	VERB
cord-000079-533xlisc	215	396	positive	positive	ADJ
cord-000079-533xlisc	215	397	cells	cell	NOUN
cord-000079-533xlisc	215	398	lowdose	lowdose	NOUN
cord-000079-533xlisc	215	399	radiation	radiation	NOUN
cord-000079-533xlisc	215	400	enhances	enhance	VERB
cord-000079-533xlisc	215	401	survivin	survivin	NOUN
cord-000079-533xlisc	215	402	-	-	PUNCT
cord-000079-533xlisc	215	403	mediated	mediate	VERB
cord-000079-533xlisc	215	404	virotherapy	virotherapy	NOUN
cord-000079-533xlisc	215	405	against	against	ADP
cord-000079-533xlisc	215	406	malignant	malignant	ADJ
cord-000079-533xlisc	215	407	glioma	glioma	NOUN
cord-000079-533xlisc	215	408	stem	stem	NOUN
cord-000079-533xlisc	215	409	cells	cell	NOUN
cord-000079-533xlisc	215	410	adenoviruses	adenovirus	NOUN
cord-000079-533xlisc	215	411	16	16	NUM
cord-000079-533xlisc	215	412	and	and	CCONJ
cord-000079-533xlisc	215	413	cv23	cv23	PROPN
cord-000079-533xlisc	215	414	efficiently	efficiently	ADV
cord-000079-533xlisc	215	415	transduce	transduce	VERB
cord-000079-533xlisc	215	416	human	human	ADJ
cord-000079-533xlisc	215	417	low	low	ADJ
cord-000079-533xlisc	215	418	-	-	PUNCT
cord-000079-533xlisc	215	419	passage	passage	NOUN
cord-000079-533xlisc	215	420	brain	brain	NOUN
cord-000079-533xlisc	215	421	tumor	tumor	NOUN
cord-000079-533xlisc	215	422	and	and	CCONJ
cord-000079-533xlisc	215	423	cancer	cancer	NOUN
cord-000079-533xlisc	215	424	stem	stem	NOUN
cord-000079-533xlisc	215	425	cells	cell	NOUN
cord-000079-533xlisc	215	426	isolation	isolation	NOUN
cord-000079-533xlisc	215	427	and	and	CCONJ
cord-000079-533xlisc	215	428	characterization	characterization	NOUN
cord-000079-533xlisc	215	429	of	of	ADP
cord-000079-533xlisc	215	430	neural	neural	ADJ
cord-000079-533xlisc	215	431	progenitor	progenitor	NOUN
cord-000079-533xlisc	215	432	cells	cell	NOUN
cord-000079-533xlisc	215	433	from	from	ADP
cord-000079-533xlisc	215	434	post	post	ADJ
cord-000079-533xlisc	215	435	-	-	ADJ
cord-000079-533xlisc	215	436	mortem	mortem	ADJ
cord-000079-533xlisc	215	437	human	human	ADJ
cord-000079-533xlisc	215	438	cortex	cortex	NOUN
cord-000079-533xlisc	215	439	bystander	bystander	NOUN
cord-000079-533xlisc	215	440	killing	killing	NOUN
cord-000079-533xlisc	215	441	of	of	ADP
cord-000079-533xlisc	215	442	malignant	malignant	ADJ
cord-000079-533xlisc	215	443	glioma	glioma	NOUN
cord-000079-533xlisc	215	444	by	by	ADP
cord-000079-533xlisc	215	445	bone	bone	NOUN
cord-000079-533xlisc	215	446	marrow	marrow	NOUN
cord-000079-533xlisc	215	447	-	-	PUNCT
cord-000079-533xlisc	215	448	derived	derive	VERB
cord-000079-533xlisc	215	449	tumorinfiltrating	tumorinfiltrate	VERB
cord-000079-533xlisc	215	450	progenitor	progenitor	NOUN
cord-000079-533xlisc	215	451	cells	cell	NOUN
cord-000079-533xlisc	215	452	expressing	express	VERB
cord-000079-533xlisc	215	453	a	a	DET
cord-000079-533xlisc	215	454	suicide	suicide	NOUN
cord-000079-533xlisc	215	455	gene	gene	NOUN
cord-000079-533xlisc	215	456	single	single	ADJ
cord-000079-533xlisc	215	457	-	-	PUNCT
cord-000079-533xlisc	215	458	shot	shot	NOUN
cord-000079-533xlisc	215	459	,	,	PUNCT
cord-000079-533xlisc	215	460	multicycle	multicycle	NOUN
cord-000079-533xlisc	215	461	suicide	suicide	NOUN
cord-000079-533xlisc	215	462	gene	gene	NOUN
cord-000079-533xlisc	215	463	therapy	therapy	NOUN
cord-000079-533xlisc	215	464	by	by	ADP
cord-000079-533xlisc	215	465	replication	replication	NOUN
cord-000079-533xlisc	215	466	-	-	PUNCT
cord-000079-533xlisc	215	467	competent	competent	ADJ
cord-000079-533xlisc	215	468	retrovirus	retrovirus	NOUN
cord-000079-533xlisc	215	469	vectors	vector	NOUN
cord-000079-533xlisc	215	470	achieves	achieve	VERB
cord-000079-533xlisc	215	471	long	long	ADJ
cord-000079-533xlisc	215	472	-	-	PUNCT
cord-000079-533xlisc	215	473	term	term	NOUN
cord-000079-533xlisc	215	474	survival	survival	NOUN
cord-000079-533xlisc	215	475	benefit	benefit	NOUN
cord-000079-533xlisc	215	476	in	in	ADP
cord-000079-533xlisc	215	477	experimental	experimental	ADJ
cord-000079-533xlisc	215	478	glioma	glioma	NOUN
cord-000079-533xlisc	215	479	we	we	PRON
cord-000079-533xlisc	215	480	thank	thank	VERB
cord-000079-533xlisc	215	481	mariana	mariana	PROPN
cord-000079-533xlisc	215	482	carstov	carstov	PROPN
cord-000079-533xlisc	215	483	,	,	PUNCT
cord-000079-533xlisc	215	484	narve	narve	PROPN
cord-000079-533xlisc	215	485	brekka	brekka	PROPN
cord-000079-533xlisc	215	486	,	,	PUNCT
cord-000079-533xlisc	215	487	roswitha	roswitha	PROPN
cord-000079-533xlisc	215	488	seyd	seyd	PROPN
cord-000079-533xlisc	215	489	,	,	PUNCT
cord-000079-533xlisc	215	490	hege	hege	NOUN
cord-000079-533xlisc	215	491	dale	dale	PROPN
cord-000079-533xlisc	215	492	and	and	CCONJ
cord-000079-533xlisc	215	493	endy	endy	PROPN
cord-000079-533xlisc	215	494	spriet	spriet	PROPN
cord-000079-533xlisc	215	495	for	for	ADP
cord-000079-533xlisc	215	496	expert	expert	ADJ
cord-000079-533xlisc	215	497	technical	technical	ADJ
cord-000079-533xlisc	215	498	assistance	assistance	NOUN
cord-000079-533xlisc	215	499	.	.	PUNCT
