item: #1 of 178 id: cord-011558-ls6cdive author: Zhang, Jingping title: An Asymptomatic Patient with COVID-19 date: 2020-06-01 words: 207 flesch: 25 summary: China A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-toperson transmission: a study of a family cluster Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study key: cord-011558-ls6cdive authors: Zhang, Jingping; Du, Yonghao; Bai, Lu; Pu, Jiantao; Jin, Chenwang; Yang, Jian; Guo, Youmin title: An Asymptomatic Patient with COVID-19 date: 2020-06-01 journal: Am J Respir Crit Care Med DOI: 10.1164/rccm.202002-0241im sha: doc_id: 11558 cord_uid: ls6cdive nan Our case verified the asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as previously reported (3, 4) and suggested that 1) the transmission of COVID-19 seemingly could occur during the incubation period and may cause a potential threat to public health, and 2) the CT examination is very helpful for the early diagnosis of COVID-19 because the abnormalities (e.g., unilateral or bilateral subpleural multifocal ground-glass opacities of the lungs) associated with COVID-19 could be visualized on CT while subjects remain asymptomatic (5) . keywords: covid-19 cache: cord-011558-ls6cdive.txt plain text: cord-011558-ls6cdive.txt item: #2 of 178 id: cord-027758-vgr6ht3a author: Wang, Tianbing title: A four-compartment model for the COVID-19 infection—implications on infection kinetics, control measures, and lockdown exit strategies date: 2020-05-28 words: 4482 flesch: 49 summary: With daily active monitoring of new infection numbers, it is possible to adjust the infection control policies to maintain new infections within a band trending downwards. The four-compartment model and the validation In our four-compartment Susceptible-Quarantined-Infected-Removed (SQIR) model, the transmissibility of COVID-19 is modelled by two factors, the per capita contact rate (β, social interaction factor, when multiplied by the ratio of infectious individuals in the population, describes the probability of a subject moving from status S to status C), and infection rate upon contact (σ , the viral transmission factor, the probability of a subject moving from status C to status E). keywords: lockdown; model; new; quarantine; use cache: cord-027758-vgr6ht3a.txt plain text: cord-027758-vgr6ht3a.txt item: #3 of 178 id: cord-029100-gxn15jgt author: Clark, Anthony E. title: Conclusion date: 2020-07-14 words: 3143 flesch: 53 summary: As anticipated, once he was in China Clet encountered disagreements between the missionaries and local officials, but what most exasperated him during his early years within the Qing empire was his initial struggle to learn Chinese. Beatrice Leung and William T. Liu authored a fine book on the history of Catholicism in modern China, and they chose to entitle their study, The Chinese Church in Conflict, emphasizing the antagonisms that China's Catholic Christians have experienced with the state, as well as Vatican tensions with Beijing's post-1940 government. keywords: catholic; china; chinese; clet; jean; perboyre; wuhan cache: cord-029100-gxn15jgt.txt plain text: cord-029100-gxn15jgt.txt item: #4 of 178 id: cord-029550-qodmamov author: Jandrić, Petar title: Review of Fang Fang (2020). Wuhan Diary: Dispatches from a Quarantined City. Trans. M. Berry: New York: HarperCollins. 377 pp. ISBN 9780063052659 (E-Book) date: 2020-07-23 words: 2566 flesch: 67 summary: Discover magazine Chinese vigilant on deifying writer Fang Fang amid publication of Wuhan diary in English. Fang's publishing house, HarperCollins, claims that '[t] he stark reality of this devastating situation drives Fang Fang to courageously speak out against social injustice, corruption, abuse, and the systemic political problems which impeded the response to the epidemic' (in Siqi 2020). keywords: chinese; critique; diary; fang; online; wuhan cache: cord-029550-qodmamov.txt plain text: cord-029550-qodmamov.txt item: #5 of 178 id: cord-030934-t7akdu6x author: Bahrami, Afsane title: Genetic and pathogenic characterization of SARS-CoV-2: a review date: 2020-08-26 words: 6490 flesch: 36 summary: SARS-CoV-2 shares 80% nucleotide identity to SARS-CoV. The S, E, M, N and ORF3a genes of SARS-CoV-2 are predicted to be 3822, 228, 669, 1260 and 828 nucleotides in length, respectively. keywords: acute; cells; coronavirus; cov-2; covid-19; covs; disease; human; infection; novel; patients; protein; response; sars; spike; treatment cache: cord-030934-t7akdu6x.txt plain text: cord-030934-t7akdu6x.txt item: #6 of 178 id: cord-031001-x4iiqq5e author: Hou, Fan Fan title: Personnel protection strategy for healthcare workers in Wuhan during the COVID-19 epidemic date: 2020-07-20 words: 2513 flesch: 44 summary: The seropositivity for SARS-CoV-2 antibodies (IgG, IgM, or both IgG/IgM positive) was 3.4% (53 out of 1571) in local healthcare workers from Wuhan with Level 2/3 PPE working in isolation areas and 5.4% (126 out of 2336) in healthcare staff with Level 1 PPE working in non-isolation medical areas, respectively. The seropositivity for SARS-CoV-2 antibodies (IgG, IgM, or both IgG/IgM positive) was 3.4% (53/1571) in local healthcare workers from Wuhan with Level 2/3 PPE working in isolation areas and 5.4% (126/2336) in healthcare staff with Level 1 PPE working in non-isolation medical areas, respectively (Table 3) . keywords: cov-2; healthcare; ppe; sars; workers; wuhan cache: cord-031001-x4iiqq5e.txt plain text: cord-031001-x4iiqq5e.txt item: #7 of 178 id: cord-103533-k1lg8c7q author: Jin, C. title: Development and Evaluation of an AI System for COVID-19 date: 2020-03-23 words: 6437 flesch: 49 summary: In the open data set LIDC-IDRI and ILD-HUG, the false positive rates of AI system were 3.12% and 11.85%, and the system showed good generalization ability (Figure 7 c ). It is hard to notice the evidence of COVID-19 in these two cases, but AI system can still identify them. keywords: ai system; cases; cohort; covid-19; diagnosis; figure; license; medrxiv; preprint; system cache: cord-103533-k1lg8c7q.txt plain text: cord-103533-k1lg8c7q.txt item: #8 of 178 id: cord-119576-8qp8o2g2 author: Xu, Liyan title: Cost-effectiveness Analysis of Antiepidemic Policies and Global Situation Assessment of COVID-19 date: 2020-04-16 words: 11587 flesch: 53 summary: We find that: 1) intercity travel restriction has minimal or even negative effect compared to the other two at the national level; 2) the time of reaching turning point is independent of the current number of cases, and only related to the enforcement stringency of epidemiological control and social interaction control measures; 3) strong enforcement at the early stage is the only opportunity to maximize both antiepidemic effectiveness and cost-effectiveness; 4) mediocre stringency of social interaction measures is the worst choice. When the two parameters are 1/4-1/3 of the normal everyday values, the turning point comes in two weeks and the clearance of cases happens in two to three months; when ! , are larger than 1/2-2/3 of the normal values, the turning point will never come, i.e., the peak value of case numbers will remain the same as if there are no such measures, but they only delay the time of peak. keywords: cases; cities; control; cost; effectiveness; epidemic; infected; interaction; level; measures; number; stage cache: cord-119576-8qp8o2g2.txt plain text: cord-119576-8qp8o2g2.txt item: #9 of 178 id: cord-136515-e0j2iruo author: Xue, Ling title: A Data-Driven Network Model for the Emerging COVID-19 Epidemics in Wuhan, Toronto and Italy date: 2020-05-28 words: 5448 flesch: 52 summary: βks k k ′ k ′ −1 This type of network model allows us to adapt changes to some realistic network structures and examine the effects of control and intervention countermeasures such as social distancing, self-isolation, and personal protection. keywords: degree k; epidemic; individuals; model; network; number; size cache: cord-136515-e0j2iruo.txt plain text: cord-136515-e0j2iruo.txt item: #10 of 178 id: cord-252804-u7tz6xzz author: Ciotti, Marco title: COVID-19 Outbreak: An Overview date: 2020-04-07 words: 3571 flesch: 45 summary: Nat Rev Microbiol Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Presumed asymptomatic carrier transmission of COVID-19 Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital of the Chinese People's Liberation Army Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions Washington State 2019-nCoV Case Investigation Team. Algorithm for the management of contacts of probable or confirmed COVID-19 cases Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens Coronavirus as a possible cause of severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease Structural insights into coronavirus entry Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein The 2019-new coronavirus epidemic: evidence for virus evolution Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1′′-phosphate dephosphorylation by a conserved domain of nsP3 COV-ID-2019: the role of the nsp2 and nsp3 in its pathogenesis The global spread of 2019-nCoV: a molecular evolutionary analysis. keywords: acid; bat; coronavirus; cov-2; covid-19; novel; position; residue; sars cache: cord-252804-u7tz6xzz.txt plain text: cord-252804-u7tz6xzz.txt item: #11 of 178 id: cord-254538-vcf44w1k author: Rocha Filho, C. R. title: PROGNOSTIC FACTORS FOR CLINICAL COURSE OF PATIENTS WITH COVID-19: PROTOCOL FOR A RAPID LIVING SYSTEMATIC REVIEW date: 2020-05-09 words: 2560 flesch: 55 summary: We will perform the critical appraisal of included studies with the Quality in Prognosis Studies (QUIPS) tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). A predefined form will be used to extract data from included studies. keywords: 2019; coronavírus; covid-19; por; preprint; studies cache: cord-254538-vcf44w1k.txt plain text: cord-254538-vcf44w1k.txt item: #12 of 178 id: cord-254968-czrgzyr3 author: Zhang, Qiang title: A serological survey of SARS-CoV-2 in cat in Wuhan date: 2020-09-17 words: 3152 flesch: 50 summary: Virus neutralization test and Western blot assay of cat serum samples for SARS-CoV-2 (A) Cat#14, Cat#15 and Cat#4 sera were 3-fold serially diluted and mixed with SARS-CoV-2; after incubated at 37°C for 1 h, the mixture was used to infect Vero E6 cells, and replaced with semi-solid media 1 h later. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan The reproductive number of COVID-19 is higher compared to SARS coronavirus Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -an update on the status Discovery of Bat coronaviruses through Surveillance and probe Capturebased Next-Generation Sequencing Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2 A pneumonia outbreak associated with a new coronavirus of probable bat origin Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)? keywords: antibody; cats; cov-2; covid-19; positive; sars; sera; serum cache: cord-254968-czrgzyr3.txt plain text: cord-254968-czrgzyr3.txt item: #13 of 178 id: cord-255905-ti9b1etu author: Qiu, Chengfeng title: Transmission and clinical characteristics of coronavirus disease 2019 in 104 outside-Wuhan patients, China date: 2020-03-06 words: 3779 flesch: 56 summary: With the increased awareness of early discovery and timely treatment, organ function damage was occurred just in few patients, that is quite different from observation of patients in Wuhan patients. For the study population, imported case was defined as an infector who emigrated from Wuhan (who ever lived in or traveled to Wuhan), the rest of study patients were defined as indigenous cases. keywords: holder; license; medrxiv; patients; peer; perpetuity; preprint cache: cord-255905-ti9b1etu.txt plain text: cord-255905-ti9b1etu.txt item: #14 of 178 id: cord-257556-lmws8eed author: Rafiq, Danish title: Three months of COVID‐19: A systematic review and meta‐analysis date: 2020-05-18 words: 3208 flesch: 39 summary: Phylogeny of SARS-Like Betacoronaviruses Including Novel Coronavirus (nCoV A pneumonia outbreak associated with a new coronavirus of probable bat origin Angiotensinconverting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A joint research team of the Shanghai Institute of Materia Medica and Shanghai Tech University discover a group of old and traditional Chinese medicines that may be efficacious in treating the novel form of pneumonia Accelerated Emergency Use Authorization (Eua) Summary Covid-19 Rapid tests for influenza, respiratory syncytial virus, and other respiratory viruses: a systematic review and meta-analysis Diagnostic indexes of a rapid IgG/IgM combined antibody test for SARS-CoV-2 Evaluation of recombinant nucleocapsid and spice protein serological diagnosis of novel coronavirus disease 2019 (COVID-19) Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis A mathematical model for simulating the transmission of Wuhan novel coronavirus Report 2: estimating the potential Total number of novel coronavirus cases in Wuhan City A family of embedded Runge-Kutta formulae Estimating the Unreported Number of Novel Coronavirus (2019-nCoV) Cases in China in the First Half of January 2020: a data-driven Modelling analysis of the early outbreak Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions An updated estimation of the risk of transmission of the novel coronavirus The reproductive number of COVID-19 is higher compared to SARS coronavirus Epidemic analysis of COVID-19 in China by dynamical modeling Estimation of the reproductive number of novel coronavirus (COVID-19) and the probable outbreak size on the diamond princess cruise ship: a data-driven analysis A mathematical model for simulating the phase-based transmissibility of a novel coronavirus Insights from early mathematical models of 2019-nCoV acute respiratory disease (COVID-19) dynamics Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action Data-based analysis, Modelling and forecasting of the COVID-19 outbreak Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China Transmission dynamics of 2019 novel coronavirus (2019-nCoV) keywords: china; coronavirus; cov-2; covid-19; novel; outbreak; patients; sars; transmission cache: cord-257556-lmws8eed.txt plain text: cord-257556-lmws8eed.txt item: #15 of 178 id: cord-258113-mnou31j3 author: Wang, Yaping title: Clinical Characteristics of Patients Infected With the Novel 2019 Coronavirus (SARS-Cov-2) in Guangzhou, China date: 2020-05-19 words: 3900 flesch: 52 summary: Imported group patients were those who had been to Wuhan within 14 days or who were residents of Wuhan before admission, and the local group included patients who had not left Guangdong during the past month. So it is important to evaluate ALB levels dynamically in these patients. RT-PCR analysis of respiratory or fecal samples, together with serological testing, can confirm the diagnosis of SARS-CoV infection in most SARS patients. keywords: coronavirus; cov-2; disease; group; patients; sars; study; wuhan cache: cord-258113-mnou31j3.txt plain text: cord-258113-mnou31j3.txt item: #16 of 178 id: cord-258748-nzynerfu author: Li, Jinghua title: Estimation of the epidemic properties of the 2019 novel coronavirus: A mathematical modeling study date: 2020-02-20 words: 3335 flesch: 40 summary: A population-based surveillance study from How generation intervals shape the relationship between growth rates and reproductive numbers A likelihood-based method for real-time estimation of the serial interval and reproductive number of an epidemic Real Time Bayesian Estimation of the Epidemic Potential of Emerging Infectious Diseases Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures The R0 package: a toolbox to estimate reproduction numbers for epidemic outbreaks The construction of next-generation matrices for compartmental epidemic models Estimating transmission intensity for a measles epidemic in Niamey, Niger: lessons for intervention Understanding the Hastings Algorithm Generalized linear models World Health Organization. Basic reproduction numbers for all fives methods for the entire time period, the pre-closure period and the post-closure period, are shown in Table 1 . keywords: closure; epidemic; number; period; reproduction; reproduction number; wuhan cache: cord-258748-nzynerfu.txt plain text: cord-258748-nzynerfu.txt item: #17 of 178 id: cord-259149-svryhcgy author: Su, Yue title: Examining the Impact of COVID-19 Lockdown in Wuhan and Lombardy: A Psycholinguistic Analysis on Weibo and Twitter date: 2020-06-24 words: 4780 flesch: 53 summary: As for the names sharing similar meanings, such as tentative from SCLIWC and possibility from Italian LIWC, we checked the meaning of words belonging to this word category in Italian LIWC and SCLIWC to determine whether the two names represented the same kind of word category. Word categories with significant differences between before and after in Weibo (n = 850). keywords: categories; liwc; lockdown; lombardy; people; use; users; words; wuhan cache: cord-259149-svryhcgy.txt plain text: cord-259149-svryhcgy.txt item: #18 of 178 id: cord-259229-e8m8m4ut author: Samidurai, Arun title: Cardiovascular Complications Associated with COVID-19 and Potential Therapeutic Strategies date: 2020-09-16 words: 10793 flesch: 30 summary: While the ACE2 gene is located on the X-chromosome, gender has an impact among COVID-19 patients, where men are at increased risk of susceptibility to COVID-19 infection and CVD complications due to their hemizygous allele for ACE2 compared to heterozygous allele in female [28] . Several promising therapeutics are under investigation to the overall prognosis of COVID-19 patients with high risk of cardiovascular impairment, nevertheless to date, none have shown proven clinical efficacy. keywords: ace2; acute; angiotensin; cardiac; cell; china; complications; coronavirus; cov-2; covid-19; covid-19 patients; disease; failure; heart; infection; mortality; patients; risk; sars; study; treatment; vaccine cache: cord-259229-e8m8m4ut.txt plain text: cord-259229-e8m8m4ut.txt item: #19 of 178 id: cord-259368-k8t8brjy author: Ren, Xiang title: Evidence for pre‐symptomatic transmission of coronavirus disease 2019 (COVID‐19) in China date: 2020-08-07 words: 3166 flesch: 40 summary: [12] these studies used cluster cases in limited number of families for analysis, and the relative frequency of pre-symptomatic transmission was not quantified. We examine the characteristics of confirmed cases and compared the demographics, onset symptoms and results of some clinical tests between confirmed sporadic and cluster primary cases and cluster secondary cases. keywords: cases; coronavirus; covid-19; onset; transmission; wuhan cache: cord-259368-k8t8brjy.txt plain text: cord-259368-k8t8brjy.txt item: #20 of 178 id: cord-261079-rarud78k author: Meng, Mei title: Rapidly organize redeployed medical staff in coronavirus disease 2019 pandemic: what we should do date: 2020-09-20 words: 1387 flesch: 45 summary: Governments and hospitals took responsibility for supplying PPE for medical staff teams, which assured that all teams participating in managing COVID-19 patients were well protected from virus contracting and spreading. [5] The mobilization and transfer of medical staff is entirely led by the government. keywords: covid-19; staff; team; wuhan cache: cord-261079-rarud78k.txt plain text: cord-261079-rarud78k.txt item: #21 of 178 id: cord-261246-m40kwgcg author: Chen, Nanshan title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study date: 2020-01-30 words: 4019 flesch: 51 summary: Patients had clinical manifestations of fever (82 [83%] patients), cough (81 [82%] patients), shortness of breath (31 [31%] patients), muscle ache (11 [11%] patients), confusion (nine [9%] patients), headache (eight [8%] patients), sore throat (five [5%] patients), rhinorrhoea (four [4%] patients), chest pain (two [2%] patients), diarrhoea (two [2%] patients), and nausea and vomiting (one [1%] patient). keywords: china; clinical; coronavirus; data; infection; ncov; patients; pneumonia; study; wuhan cache: cord-261246-m40kwgcg.txt plain text: cord-261246-m40kwgcg.txt item: #22 of 178 id: cord-262104-oig3qrr7 author: Brüssow, Harald title: COVID‐19: Test, Trace and Isolate‐New Epidemiological Data date: 2020-06-08 words: 7130 flesch: 50 summary: One in ten of >1'300 accredited nursing facilities reported COVID-19 cases. The control measures that stopped the epidemic locally have included: intense infection surveillance of incoming travelers; isolation of COVID-19 cases in hospitals; contact tracing and quarantine in holiday camps; and school closure but no lock-down, thus preventing the crisis from having a negative economic impact. keywords: cases; china; cov-2; covid-19; deaths; epidemic; health; infection; influenza; number; population; rate; sars; transmission cache: cord-262104-oig3qrr7.txt plain text: cord-262104-oig3qrr7.txt item: #23 of 178 id: cord-262693-z9dolxky author: Nishiura, Hiroshi title: Initial Cluster of Novel Coronavirus (2019-nCoV) Infections in Wuhan, China Is Consistent with Substantial Human-to-Human Transmission date: 2020-02-11 words: 1458 flesch: 36 summary: The clinical summary of the earliest cases of 2019 novel coronavirus (2019-nCoV) infections in Wuhan, China was recently published [1] , showing the majority of cases were exposed to the Huanan seafood market, which also had wild animals, suggesting the possibility of zoonotic transmission in the market. First, Figure 1A shows the epidemic curve of cases in Wuhan, distinguishing case generations by color. keywords: human; transmission cache: cord-262693-z9dolxky.txt plain text: cord-262693-z9dolxky.txt item: #24 of 178 id: cord-265206-ddg87zxv author: Kanny, G. title: Maladies respiratoires, allergies et infections à COVID-19. Premières nouvelles de Wuhan date: 2020-04-01 words: 994 flesch: 62 summary: Il est conseillé d'aérer son domicile tôt le matin et à la tombée de la nuit. étudier l'expression d'ECA2 dans les cellules épithéliales des patients porteurs de BPCO et des fumeurs. keywords: des; est; les; patients cache: cord-265206-ddg87zxv.txt plain text: cord-265206-ddg87zxv.txt item: #25 of 178 id: cord-266738-8xx1xm2d author: None title: cord-266738-8xx1xm2d date: None words: 14692 flesch: 44 summary: Increasing reports on human PRV infection cases in China have recently indicated that PRV poses a significant threat to public health in China, especially in people in close contact with sick pigs and/or related pork products/contaminants. 3 , 8 Here we explored a simple data-driven, Boltzmann functionbased approach for estimation only based on the daily cumulative number of confirmed cases of SARS-CoV-2 (Note: the rational for Boltzmann function-based regression analysis is presented in supporting information (SI) file). keywords: 2019; cases; china; colistin; control; data; disease; gene; health; human; infection; isolates; laboratory; novel; number; outbreak; patients; pcr; pertussis; pjp; pneumoniae; prv; resistance; table; time; treatment cache: cord-266738-8xx1xm2d.txt plain text: cord-266738-8xx1xm2d.txt item: #26 of 178 id: cord-266963-belin2jq author: Cowling, Benjamin J title: Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak date: 2020-02-13 words: 2454 flesch: 35 summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China China says coronavirus can spread before symptoms show --calling into question US containment strategy Estimating variability in the transmission of severe acute respiratory syndrome to household contacts in Hong Kong, China Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study The Dynamic Relationship Between Clinical Symptomatology and Viral Shedding in Naturally Acquired Seasonal and Pandemic Influenza Virus Infections Recognition of aerosol transmission of infectious agents: a commentary Coronavirus as a possible cause of severe acute respiratory syndrome Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus Severe acute respiratory syndrome beyond Amoy Gardens: completing the incomplete legacy Sixty more people confirmed with coronavirus on cruise ship in Japan: media. It is well established that some infections can be severe, particularly in older adults with underlying medical conditions [15, 16] , but based on the generally mild clinical presentation of 2019-nCoV cases detected outside China, it appears that there could be many more mild infections than severe infections. keywords: china; coronavirus; infections; measures; ncov; transmission cache: cord-266963-belin2jq.txt plain text: cord-266963-belin2jq.txt item: #27 of 178 id: cord-267548-7mcfehzc author: Mizumoto, Kenji title: Estimating Risk for Death from Coronavirus Disease, China, January–February 2020 date: 2020-06-17 words: 2733 flesch: 38 summary: We defined crude CFR as the number of cumulative deaths divided by the number of cumulative cases at a specific point in time. First, we extracted the daily series of confirmed cases and deaths in China from daily reports published by the respective governments of China, Hubei Province, and the city of Wuhan (8) (9) (10) (11) (12) . keywords: cfr; china; estimates; hubei; province; wuhan cache: cord-267548-7mcfehzc.txt plain text: cord-267548-7mcfehzc.txt item: #28 of 178 id: cord-267574-etnjo4nz author: Zhao, Shi title: The association between domestic train transportation and novel coronavirus (2019-nCoV) outbreak in China from 2019 to 2020: A data-driven correlational report date: 2020-02-29 words: 1094 flesch: 55 summary: The map of major cities with imported nCoV cases and the its regression fitting results against train transportation. Panel (B) shows the daily number of passengers by train versus the total number of imported nCoV cases in each city. keywords: cases; ncov; number cache: cord-267574-etnjo4nz.txt plain text: cord-267574-etnjo4nz.txt item: #29 of 178 id: cord-269453-30l6rzgo author: Yang, Po title: Feasibility study of mitigation and suppression strategies for controlling COVID-19 outbreaks in London and Wuhan date: 2020-08-06 words: 6785 flesch: 49 summary: Suppression intervention from the 32 nd day: the peak of daily infections greatly reduced to 16 thousand, but it had to be followed at least 200 days. We used a benchmark reported in [11] that assumes Hubei province with no intervention as M = 15, and after suppression intervention, M reduced to 3. keywords: cases; covid-19; intervention; london; model; number; population; suppression; wuhan cache: cord-269453-30l6rzgo.txt plain text: cord-269453-30l6rzgo.txt item: #30 of 178 id: cord-273064-c58nf9vb author: Hallowell, Benjamin D. title: Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020 date: 2020-09-17 words: 3535 flesch: 39 summary: key: cord-273064-c58nf9vb authors: Hallowell, Benjamin D.; Carlson, Christina M.; Jacobs, Jesica R.; Pomeroy, Mary; Steinberg, Jonathan; Tenforde, Mark W.; McDonald, Emily; Foster, Loretta; Feldstein, Leora R.; Rolfes, Melissa A.; Haynes, Amber; Abedi, Glen R.; Odongo, George S.; Saruwatari, Kim; Rider, Errin C.; Douville, Gina; Bhakta, Neenaben; Maniatis, Panagiotis; Lindstrom, Stephen; Thornburg, Natalie J.; Lu, Xiaoyan; Whitaker, Brett L.; Kamili, Shifaq; Sakthivel, Senthilkumar K.; Wang, Lijuan; Malapati, Lakshmi; Murray, Janna R.; Lynch, Brian; Cetron, Martin; Brown, Clive; Roohi, Shahrokh; Rotz, Lisa; Borntrager, Denise; Ishii, Kenta; Moser, Kathleen; Rasheed, Mohammad; Freeman, Brandi; Lester, Sandra; Corbett, Kizzmekia S.; Abiona, Olubukola M.; Hutchinson, Geoffrey B.; Graham, Barney S.; Pesik, Nicki; Mahon, Barbara; Braden, Christopher; Behravesh, Casey Barton; Stewart, Rebekah; Knight, Nancy; Hall, Aron J.; Killerby, Marie E. title: Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020 date: 2020-09-17 journal: Emerg Infect Dis DOI: 10.3201/eid2609.201590 sha: doc_id: 273064 cord_uid: c58nf9vb To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. keywords: coronavirus; cov-2; covid-19; evacuees; sars; states; united; wuhan cache: cord-273064-c58nf9vb.txt plain text: cord-273064-c58nf9vb.txt item: #31 of 178 id: cord-273209-ou80n3p3 author: Zheng, Fang title: Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China date: 2020-03-24 words: 2619 flesch: 50 summary: The majority of pediatric patients had mild symptoms. The occurrence of mild illness in pediatric patients has no clear explanation. keywords: cases; children; china; covid-19; infection; patients; years cache: cord-273209-ou80n3p3.txt plain text: cord-273209-ou80n3p3.txt item: #32 of 178 id: cord-273692-jwqrfb6h author: Golinelli, D. title: The impact of early scientific literature in response to COVID-19: a scientometric perspective date: 2020-04-18 words: 4453 flesch: 45 summary: This can be done by capturing and measuring traditional citations of scientific papers but also through the use of innovative and alternative scientometrics tools. Due to the extraordinary rapidity with which scientific papers have been electronically published online (i.e. ePub), it may happen that some of these have indicated a date later than February 13 2020 as publication date. keywords: citations; coronavirus; covid-19; impact; media; papers; research; study cache: cord-273692-jwqrfb6h.txt plain text: cord-273692-jwqrfb6h.txt item: #33 of 178 id: cord-275765-58iul47s author: Yao, Wenlong title: Critical role of Wuhan cabin hospitals in controlling the local COVID-19 pandemic date: 2020-04-22 words: 1156 flesch: 51 summary: key: cord-275765-58iul47s authors: Yao, Wenlong; Wang, Xueren; Liu, Tianzhu title: Critical role of Wuhan cabin hospitals in controlling the local COVID-19 pandemic date: 2020-04-22 journal: Infection control and hospital epidemiology DOI: 10.1017/ice.2020.167 sha: doc_id: 275765 cord_uid: 58iul47s nan To the Editor-COVID-19 is quickly spreading all over the world. Here, we evaluate the role of cabin hospitals in controlling the COVID-19 pandemic by retrospectively analyzing the correlation between available beds in cabin hospitals and epidemic data. keywords: cabin; cases; covid-19 cache: cord-275765-58iul47s.txt plain text: cord-275765-58iul47s.txt item: #34 of 178 id: cord-275835-z38cgov9 author: Mogharab, Vahid title: The first case of COVID-19 infection in a 75-day-old infant in Jahrom City, south of Iran date: 2020-04-13 words: 639 flesch: 53 summary: While COVID-19 infection seems to be more prevalent in adults than in children, rare cases of children infection are being reported, mainly seen in family clusters. key: cord-275835-z38cgov9 authors: Mogharab, Vahid; Pasha, Anahita Manafi Khajeh; Javdani, Frashid; Hatami, Naser title: The first case of COVID-19 infection in a 75-day-old infant in Jahrom City, south of Iran date: 2020-04-13 journal: J Formos Med Assoc DOI: 10.1016/j.jfma.2020.03.015 sha: doc_id: 275835 cord_uid: z38cgov9 nan The first case of COVID-19 infection in a 75day-old infant in Jahrom City, south of Iran In late December of 2019, a new coronavirus was discovered in China. keywords: covid-19; infection cache: cord-275835-z38cgov9.txt plain text: cord-275835-z38cgov9.txt item: #35 of 178 id: cord-275853-fym8qze2 author: Yang, Juan title: Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China date: 2020-09-01 words: 6459 flesch: 44 summary: The probability of seeking medical treatment conditionally on 220 symptoms of acute respiratory diseases is a critical parameter to estimate the true 221 number of COVID-19 cases in community. Accordingly, the daily number 476 of COVID-19 cases by symptom onset date was preferred to the aggregated 477 cumulative data. keywords: cases; copyright holder; funder; license; medrxiv preprint; peer review; preprint; september; version cache: cord-275853-fym8qze2.txt plain text: cord-275853-fym8qze2.txt item: #36 of 178 id: cord-277430-x02u7oh0 author: Zhang, Hongyan title: Outcomes of novel coronavirus disease 2019 (COVID‐19) infection in 107 patients with cancer from Wuhan, China date: 2020-06-23 words: 3188 flesch: 38 summary: French consensus on management of head and neck cancer surgery during COVID-19 pandemic A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: an international collaborative group Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Information for laboratories about coronavirus (COVID-19) key: cord-277430-x02u7oh0 authors: Zhang, Hongyan; Wang, Linwei; Chen, Yuanyuan; Wu, Qiuji; Chen, Gaili; Shen, Xiaokun; Wang, Qun; Yan, Youqin; Yu, Yi; Zhong, Yahua; Wang, Xinghuan; Chua, Melvin L. K.; Xie, Conghua title: Outcomes of novel coronavirus disease 2019 (COVID‐19) infection in 107 patients with cancer from Wuhan, China date: 2020-06-23 journal: Cancer DOI: 10.1002/cncr.33042 sha: doc_id: 277430 cord_uid: x02u7oh0 BACKGROUND: Patients with cancer have a higher risk of coronavirus disease 2019 (COVID‐19) than noncancer patients. keywords: anticancer; cancer; covid-19; patients; study; treatment; wuhan cache: cord-277430-x02u7oh0.txt plain text: cord-277430-x02u7oh0.txt item: #37 of 178 id: cord-278325-ykcd7d59 author: Cheung, Carmen Ka Man title: Coronavirus Disease 2019 (COVID-19): A Haematologist's Perspective date: 2020-07-28 words: 7682 flesch: 35 summary: Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. [45] evaluated lymphocyte subsets in 103 patients, which revealed that CD3+, CD4+, and CD8+ T cells and NK cells were significantly decreased in COVID-19 patients with a more severe decrease in CD8+ T cells compared with CD4+ T cells. keywords: admission; blood; cells; clinical; coronavirus; cov-2; covid-19; disease; infection; lymphocyte; non; patients; platelet; risk; sars; study; treatment cache: cord-278325-ykcd7d59.txt plain text: cord-278325-ykcd7d59.txt item: #38 of 178 id: cord-278638-2dm54f6l author: Huang, Ian title: Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis date: 2020-05-24 words: 3107 flesch: 46 summary: Regressionbased Harbord's test showed no evidence of small-study effects (p = 0.086) for lymphopenia and severe COVID-19 outcome. Lymphocyte count has been a marker of interest since the first COVID-19 publication. keywords: analysis; count; covid-19; lymphocyte; meta; outcome; patients cache: cord-278638-2dm54f6l.txt plain text: cord-278638-2dm54f6l.txt item: #39 of 178 id: cord-279255-v861kk0i author: Dhama, Kuldeep title: Coronavirus Disease 2019–COVID-19 date: 2020-06-24 words: 23944 flesch: 36 summary: Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein Animal models for SARS and MERS coronaviruses Recent advances in the vaccine development against Middle East respiratory syndromecoronavirus Virology: SARS virus infection of cats and ferrets A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters Animal models and vaccines for SARS-CoV infection Infection with MERS-CoV causes lethal pneumonia in the common marmoset Vaccines for the prevention against the threat of MERS-CoV Molecular basis of coronavirus virulence and vaccine development Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection Genetically engineering a susceptible mouse model for MERS-CoV-induced acute respiratory distress syndrome Prospects for a MERS-CoV spike vaccine A mouse model for MERS coronavirus-induced acute respiratory distress syndrome Replicative capacity of MERS coronavirus in livestock cell lines Entry of human coronavirus NL63 into the cell China's response to a novel coronavirus stands in stark contrast to the 2002 SARS outbreak response Novel coronavirus is putting the whole world on alert Early epidemiological analysis of the coronavirus disease 2019 outbreak based on crowdsourced data: a population-level observational study Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus The progress of 2019 novel coronavirus (2019-nCoV) event in China Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Response to the emerging novel coronavirus outbreak Potential for global spread of a novel coronavirus from China Novel coronavirus, poor quarantine, and the risk of pandemic Novel Coronavirus outbreak in Wuhan, China, 2020: intense surveillance is vital for preventing sustained transmission in new locations Risk for transportation of 2019 novel coronavirus disease from Wuhan to other cities in China Infections without borders: a new coronavirus in Wuhan, China An interactive web-based dashboard to track COVID-19 in real time Limiting spread of COVID-19 from cruise ships-lessons to be learnt from Japan Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records A case of 2019 novel coronavirus in a pregnant woman with preterm delivery Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study A pregnant woman with COVID-19 in Central America Latin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19). CEPI to fund three programmes to develop vaccines against the novel coronavirus, nCoV-2019 Moderna announces funding award from CEPI to accelerate development of messenger RNA (mRNA) vaccine against novel coronavirus Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms Treatment with interferon-␣2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics Potential antiviral therapeutics for 2019 novel coronavirus A novel coronavirus outbreak of global health concern Coronavirusesdrug discovery and therapeutic options Treatment with lopinavir/ritonavir or interferon-␤1b improves outcome of MERS-CoV infection in a nonhuman primate model of common Marmoset Treatment of Middle East respiratory syndrome with a combination of lopinavir-ritonavir and interferon-␤1b (MIRACLE trial): study protocol for a randomized controlled trial Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein Characterization of novel monoclonal antibodies against MERScoronavirus spike protein Crossneutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses New coronavirus threat galvanizes scientists Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection Potential interventions for novel coronavirus in China: a systemic review Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism Inhibitors of RAS might be a good choice for the therapy of COVID-19 pneumonia Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture keywords: acute; animal; bat; cases; cell; china; control; coronavirus; cov-2; covid-19; covs; disease; drugs; health; host; human; infection; mers; ncov; novel; novel coronavirus; outbreak; patients; pneumonia; potential; protein; respiratory; risk; sars; sars coronavirus; spread; studies; study; syndrome; transmission; treatment; vaccine; viruses; wuhan cache: cord-279255-v861kk0i.txt plain text: cord-279255-v861kk0i.txt item: #40 of 178 id: cord-279415-s823mver author: Guo, Xiaodong title: Survey of COVID-19 Disease Among Orthopaedic Surgeons in Wuhan, People’s Republic of China date: 2020-04-23 words: 3431 flesch: 49 summary: Orthopaedic surgeons are at risk during the COVID-19 pandemic. Orthopaedic surgeons have to be more vigilant and take more precautions to avoid infection with COVID-19. keywords: control; covid-19; health; infection; orthopaedic; surgeons; wuhan cache: cord-279415-s823mver.txt plain text: cord-279415-s823mver.txt item: #41 of 178 id: cord-279569-289fu2yb author: Lei, Yu title: Clinical features of imported cases of coronavirus disease 2019 in Tibetan patients in the Plateau area date: 2020-03-13 words: 2294 flesch: 53 summary: No patient had a history of exposure to COVID-19 patients from Wuhan or had travelled to Wuhan. Despite the publication of many articles regarding the clinical features of COVID-19 patients, most of these patients were considered in the context of Wuhan. keywords: medrxiv; patients; preprint; wuhan cache: cord-279569-289fu2yb.txt plain text: cord-279569-289fu2yb.txt item: #42 of 178 id: cord-279976-juz9jnfk author: Xie, Mingxuan title: Insight into 2019 novel coronavirus — an updated intrim review and lessons from SARS-CoV and MERS-CoV date: 2020-04-01 words: 3921 flesch: 42 summary: JAMA 2020a Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Decoding the evolution and transmissions of the novel pneumonia coronavirus (SARS-CoV-2) using whole genomic data Summary of probable SARS cases with onset of illness from 1 WHO . MedRxiv(preprint) 2020 MERS transmission and risk factors: a systematic review Lung pathology and pathogenesis of severe acute respiratory syndrome: a report of six full autopsies A report on the general observation of a 2019 novel coronavirus autopsy Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. keywords: 2019; clinical; coronavirus; covid-19; mers; ncov; novel; patients; sars cache: cord-279976-juz9jnfk.txt plain text: cord-279976-juz9jnfk.txt item: #43 of 178 id: cord-280786-944pn0k9 author: Wang, Chaolong title: Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China date: 2020-03-06 words: 4939 flesch: 47 summary: Covid-19 cases from December 2019 till February 18, 2020 were extracted on February 19 from the municipal Notifiable Disease Report System, including the general information of birth date, sex, occupation, residential district, date of illness onset (the self-reported date of symptoms such as fever, cough, or other respiratory . Several recent reports also highlighted the difficulty to detect Covid-19 cases: about two thirds of the cases exported from mainland China remained undetected worldwide, 24 and the detection capacity varied from 11% in low surveillance countries to 40% in high surveillance countries. keywords: author; cases; funder; license; medrxiv; medrxiv preprint; preprint cache: cord-280786-944pn0k9.txt plain text: cord-280786-944pn0k9.txt item: #44 of 178 id: cord-280892-net44oxu author: Zhan, Yu-xin title: Prevalence and Influencing Factors on Fatigue of First-line Nurses Combating with COVID-19 in China: A Descriptive Cross-Sectional Study date: 2020-08-07 words: 5660 flesch: 41 summary: The scores are added from items 1 to 8 to get the scores of physical fatigue, and the scores are added from items 9 to 14 to get the scores of mental fatigue, while the total score of fatigue is the sum of the scores of physical and mental fatigue. The median score of physical fatigue was 3 (1, 6), the median score of mental fatigue was 1 (0, 3). keywords: anxiety; care; fatigue; health; line; nurses; score; stress; study; variables; work cache: cord-280892-net44oxu.txt plain text: cord-280892-net44oxu.txt item: #45 of 178 id: cord-280970-gy0kfhy6 author: Peng, Fujun title: Management and Treatment of COVID-19: The Chinese Experience date: 2020-04-17 words: 2634 flesch: 32 summary: Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected2020 Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019. The Lancet On the use of corticosteroids for 2019-nCoV pneumonia Retrospective study of side effects of low-dose glucocorticoids in rheumatoid arthritis Early, low-dose and short-term application of corticosteroid treatment in patients with severe COVID-19 pneumonia: single-center experience from Wuhan, China. keywords: china; coronavirus; covid-19; novel; patients; pneumonia; sars; treatment; wuhan cache: cord-280970-gy0kfhy6.txt plain text: cord-280970-gy0kfhy6.txt item: #46 of 178 id: cord-281102-ohbm78it author: Gutzeit, Andreas title: What can European radiologists learn from the outbreak of COVID-19 in China? A discussion with a radiologist from Wuhan date: 2020-04-08 words: 1426 flesch: 47 summary: Patient crossing was reduced as much as possible and the distance between patients was more than 2 m. Special times were reserved in the radiology departments for possible and confirmed COVID-19 patients, if the patients could not be separated due to lack of equipment or space. We expect an enormous increase of COVID-19 patients in the next weeks and months all over the world and also in Europe. keywords: covid-19; outbreak; patients; radiology; wuhan cache: cord-281102-ohbm78it.txt plain text: cord-281102-ohbm78it.txt item: #47 of 178 id: cord-282058-it0ojdk3 author: Yu, Yuanqiang title: Coronavirus Disease 2019 (COVID-19) in Neonates and Children From China: A Review date: 2020-05-15 words: 7506 flesch: 41 summary: (COVID-19) in Zhejiang, China: an observational cohort study A case report of neonatal COVID-19 infection in China Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention SARS-CoV-2 infection in children Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Report of the first cases of mother and infant infections with 2019 novel coronavirus in Xinyang City Henan Province SARS-CoV-2 infection with gastrointestinal symptoms as the first manifestation in a neonate Antibodies in infants born to mothers with COVID-19 Pneumonia Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions The progress of 2019 novel coronavirus event in China Mitigate the effects of home confinement on children during the COVID-19 outbreak Initial public health response and interim clinical guidance for the 2019 novel coronavirus outbreak -United States US emergency legal responses to novel coronavirus: balancing public health and civil liberties Emerging coronaviruses: genome structure, replication, and pathogenesis Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A pneumonia outbreak associated with a new coronavirus of probable bat origin Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Identifying SARS-CoV-2 related coronaviruses in malayan pangolins Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding Virological assessment of hospitalized patients with COVID-2019 SARS-CoV-2 viral load in upper respiratory specimens of infected patients Pathological findings of COVID-19 associated with acute respiratory distress syndrome Emerging respiratory infections: the infectious disease pathology of SARS, MERS, pandemic influenza, and Legionella Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus SARS-CoV-2 productively infects human gut enterocytes Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study What are the risks of COVID-19 infection in pregnant women? However, at least five neonates born to COVID-19 pregnant women tested positive for SARS-CoV-2 (23, 26, 27) . keywords: cases; children; china; coronavirus; cov-2; covid-19; disease; infection; neonates; novel; patients; sars; women cache: cord-282058-it0ojdk3.txt plain text: cord-282058-it0ojdk3.txt item: #48 of 178 id: cord-282652-2w3bx6p8 author: Sun, Haoyang title: Estimating number of global importations of COVID-19 from Wuhan, risk of transmission outside mainland China and COVID-19 introduction index between countries outside mainland China date: 2020-02-20 words: 4400 flesch: 41 summary: Next, we propagated the uncertainty in the estimated number of imported COVID-19 cases from Wuhan, and estimated the probability that a local outbreak would occur and sustain for at least three generations (hereinafter referred to as local outbreak risk) for each country or territory outside mainland China. Methods We used the reported number of cases imported from Wuhan and flight data to generate an uncertainty distribution for the estimated number of imported cases from Wuhan to each location outside mainland China. keywords: cases; china; countries; outside; risk; wuhan cache: cord-282652-2w3bx6p8.txt plain text: cord-282652-2w3bx6p8.txt item: #49 of 178 id: cord-283048-hyjzofps author: Steele, Edward J. title: Origin of new emergent Coronavirus and Candida fungal diseases—Terrestrial or cosmic? date: 2020-07-14 words: 7536 flesch: 51 summary: It suggests, first, massive region-wide physical contamination with potentially trillions of infective COVID-19 viral particles in central China-contaminating buildings, roadways, cars and factory equipment, vegetation, surface water pools, people (and their clothes, body parts such as hair, skin, personal affects, mobile phone, keys, wallets, etc.) as well as wild and domestic animals, etc. The Lancet On the origins of a species: What might explain the rise of Candida auris Candida auris: A Review of the Literature Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding. keywords: auris; candida; china; covid-19; disease; et al; fall; human; new; particles; spread; time; virus; wickramasinghe; wuhan cache: cord-283048-hyjzofps.txt plain text: cord-283048-hyjzofps.txt item: #50 of 178 id: cord-283891-m36un1y2 author: Hu, Bisong title: First, second and potential third generation spreads of the COVID-19 epidemic in mainland China: an early exploratory study incorporating location-based service data of mobile devices date: 2020-05-17 words: 4664 flesch: 41 summary: Conclusions The findings provide important foundations to quantify the effect of human movement on epidemic spread and inform ongoing control strategies. The results indicate the spatiotemporal characteristics of the epidemic spread associated to human movements from epidemic sources and the potential spatiotemporal risks at the early stage of the outbreak. keywords: china; epidemic; generation; hubei; spread; wuhan cache: cord-283891-m36un1y2.txt plain text: cord-283891-m36un1y2.txt item: #51 of 178 id: cord-283985-8mdnkegz author: Yang, Chayu title: A mathematical model for the novel coronavirus epidemic in Wuhan, China date: 2020-03-11 words: 4960 flesch: 50 summary: The new coronavirus: What we do-and don't-know Centers for Disease Control and Prevention: 2019 novel coronavirus 2019-nCoV) situation reports A novel coronavirus emerging in China -key questions for impact assessment WHO statement regarding the outbreak of novel coronavirus (2019-nCoV), 2020 Available from Transmission of 2019-nCoV Infection from an asymptomatic contact in Germany Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Novel coronavirus 2019n-CoV: early estimation of epidemiological parameters and epidemic predictions, medRxiv Estimation of the transmission risk of 2019-nCoV and its implication for public health interventions Transmissibility of 2019-nCoV, Reference Source Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm, bioRxiv A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Novel coronavirus: where we are and what we know novel coronavirus (COVID-19) outbreak: A review of the current literature Human coronaviruses: Insights into environmental resistance and its influence on the development of new antiseptic strategies Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission The Stability of Dynamical Systems Persistence under relaxed point-dissipativity (with application to an endemic model) An SIS patch model with variable transmission coefficients Global stability of SEIRS models in epidemiology Global stability of infectious disease models using Lyapunov functions Wikipedia on the timeline of the 2019-20 Wuhan coronavirus outbreak Sina news real-time reports on novel coronavirus The government of Wuhan homepage Epidemiological parameter review and comparative dynamics of influenza, respiratory syncytial virus, rhinovirus, human coronvirus, and adenovirus, medRxiv A cholera transmission model incorporating the impact of medical resources The Health Commission of Hubei Province Multiple transmission pathways and disease dynamics in a waterborne pathogen model This work is partially supported by the National Institutes of Health under grant number 1R15GM131315. The values of these parameters are not available in the literature because the models published thus far have not considered the environmental component for the COVID-19 infection, and they have generally applied constant transmission rates which remain fixed in time. keywords: coronavirus; data; disease; model; transmission; wuhan cache: cord-283985-8mdnkegz.txt plain text: cord-283985-8mdnkegz.txt item: #52 of 178 id: cord-284376-plwyjhl8 author: Fu, Xinmiao title: Simulating and forecasting the cumulative confirmed cases of SARS-CoV-2 in China by Boltzmann function-based regression analyses date: 2020-05-31 words: 14755 flesch: 44 summary: Increasing reports on human PRV infection cases in China have recently indicated that PRV poses a significant threat to public health in China, especially in people in close contact with sick pigs and/or related pork products/contaminants. Potential total numbers of confirmed cases in different regions were estimated. keywords: 2019; cases; china; colistin; control; data; disease; gene; health; human; infection; isolates; laboratory; novel; number; outbreak; patients; pcr; pertussis; pjp; pneumoniae; resistance; sars; table; time; treatment cache: cord-284376-plwyjhl8.txt plain text: cord-284376-plwyjhl8.txt item: #53 of 178 id: cord-284393-s9qp9a4e author: Wei, Yiping title: Clinical characteristics of 276 hospitalized patients with coronavirus disease 2019 in Zengdu District, Hubei Province: a single-center descriptive study date: 2020-07-29 words: 4272 flesch: 48 summary: In terms of laboratory tests, 75% of patients had lymphopenia, and more obvious findings were noted in severe patients. [14] showed that the age of severe patients was significantly older than that of non-severe patients. keywords: characteristics; clinical; coronavirus; covid-19; disease; hospital; patients; study; wuhan cache: cord-284393-s9qp9a4e.txt plain text: cord-284393-s9qp9a4e.txt item: #54 of 178 id: cord-284890-s73hljz9 author: Kang, Lijun title: Impact on mental health and perceptions of psychological care among medical and nursing staff in Wuhan during the 2019 novel coronavirus disease outbreak: A cross-sectional study date: 2020-03-30 words: 4151 flesch: 38 summary: key: cord-284890-s73hljz9 authors: Kang, Lijun; Ma, Simeng; Chen, Min; Yang, Jun; Wang, Ying; Li, Ruiting; Yao, Lihua; Bai, Hanping; Cai, Zhongxiang; Xiang Yang, Bing; Hu, Shaohua; Zhang, Kerang; Wang, Gaohua; Ma, Ci; Liu, Zhongchun title: Impact on mental health and perceptions of psychological care among medical and nursing staff in Wuhan during the 2019 novel coronavirus disease outbreak: A cross-sectional study date: 2020-03-30 journal: Of all participants, 36.3% had accessed psychological materials (such as books on mental health), 50.4% had accessed psychological resources available through media (such as online push messages on mental health self-help coping methods), and 17.5% had participated in counseling or psychotherapy. keywords: care; covid-19; disturbances; exposure; health; mental; nursing; services; staff cache: cord-284890-s73hljz9.txt plain text: cord-284890-s73hljz9.txt item: #55 of 178 id: cord-285153-schpgyo0 author: Lin, Chen title: COVID-19 pneumonia patient without clear epidemiological history outside Wuhan: An analysis of the radiographic and clinical features date: 2020-04-24 words: 676 flesch: 54 summary: COVID-19 pneumonia patient without clear epidemiological history outside Wuhan: An analysis of the radiographic and clinical features date: 2020-04-24 journal: Moreover, timely nucleic acid testing should be performed when radiographic findings present similarly to those of patients with COVID-19. keywords: patient cache: cord-285153-schpgyo0.txt plain text: cord-285153-schpgyo0.txt item: #56 of 178 id: cord-285315-7r44j3q9 author: Bein, Berthold title: SARS-CoV-2/COVID-19: Empfehlungen zu Diagnostik und Therapie date: 2020-04-09 words: 2255 flesch: 41 summary: Angesteckten pro Infizierten über der von SARS. Intensive Care Med Empfehlungen zur intensivmedizinischen Therapie von Patienten mit COVID-19 Extravascular lung water predicts progression to acute lung injury in patients with increased risk Best practice & research clinical anaesthesiology: keywords: bei; china; clinical; coronavirus; cov-2; covid-19; das; der; die; eine; mit; patienten; patients; sars; sich; und; von; werden cache: cord-285315-7r44j3q9.txt plain text: cord-285315-7r44j3q9.txt item: #57 of 178 id: cord-285403-h8ahn8fw author: Zhang, Liangsheng title: Origin and Evolution of the 2019 Novel Coronavirus date: 2020-02-03 words: 850 flesch: 53 summary: This indicates that there should be more bat viruses closer to 2019-nCoV. According to their phylogenetic relationships, the 27 isolates of 2019-nCoV examined in this study can be divided into at least 6 genotypes (I-VI; Figure 1C ). The 2019-nCoV has infected several hundred humans and has caused many fatal cases. keywords: 2019; ncov cache: cord-285403-h8ahn8fw.txt plain text: cord-285403-h8ahn8fw.txt item: #58 of 178 id: cord-285502-rvv64190 author: Yang, Lie title: Emergency response to the explosive growth of health care wastes during COVID-19 pandemic in Wuhan, China date: 2020-08-18 words: 4133 flesch: 39 summary: In the first stage, the operation loading rate of HCWs treatment facility was 93.71%, which was quite close to full loading operation conditions of treatment facilities. The amount of the stored but untreated HCWs is demonstrated in The high-load period of the residual stored amount is mainly within the second stage of HCWs treatment. keywords: covid-19; facilities; hcws; hospitals; management; treatment; waste; wuhan cache: cord-285502-rvv64190.txt plain text: cord-285502-rvv64190.txt item: #59 of 178 id: cord-285772-4xt4anq5 author: Huang, Rui title: Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study date: 2020-05-08 words: 3382 flesch: 56 summary: The age of severe patients was comparable with non-severe patients (median age 49.0 yr vs. 44.0 yr, P = 0.066) and the BMI index of severe patients was higher than non-severe patients (median BMI, 26.4 kg/m 2 vs. 24.2 kg/m 2 , P = 0.004). [ Compared to non-severe patients, severe patients presented higher percentage of shortness of breath (7.3% vs. 26.1%, P = 0.004), lower lymphocytes (median 0.8 ×10 9 /L vs. 1.2×10 9 /L, P<0.001) and albumin (ALB) levels (median 38.1 g/L vs. 41.1 g/L, P = 0.002). keywords: clinical; coronavirus; covid-19; patients; severe; study; wuhan cache: cord-285772-4xt4anq5.txt plain text: cord-285772-4xt4anq5.txt item: #60 of 178 id: cord-286683-mettlmhz author: Ortiz-Prado, Esteban title: Clinical, molecular and epidemiological characterization of the SARS-CoV2 virus and the Coronavirus disease 2019 (COVID-19), a comprehensive literature review date: 2020-05-30 words: 13331 flesch: 37 summary: medRxiv Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Temporal dynamics in viral shedding and transmissibility of COVID-19 Presumed asymptomatic carrier transmission of COVID-19 Potential presymptomatic transmission of SARS-CoV-2 Interferon-stimulated genes and their antiviral effector functions RIG-I in RNA virus recognition RNA recognition and signal transduction by RIG-I-like receptors Recognition of viral single-stranded RNA by Toll-like receptors Mechanisms of innate immune evasion in re-emerging RNA viruses Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections Immunopathogenesis of coronavirus infections: implications for SARS Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Middle East respiratory syndrome Interaction of SARS and MERS coronaviruses with the antiviral interferon response SARS and MERS: recent insights into emerging coronaviruses Dysregulation of immune response in patients with COVID-19 in Wuhan Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of the macrophage activation syndrome: Re-analysis of a prior Phase III trial A multicenter, randomized controlled trial for the efficacy and safety of tocilizumab in the treatment of new coronavirus pneumonia (COVID-19) Effects of chloroquine on viral infections: an old drug against today's diseases Chloroquine is a potent inhibitor of SARS coronavirus infection and spread In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Baricitinib as potential treatment for 2019-nCoV acute respiratory disease COVID-19: consider cytokine storm syndromes and immunosuppression. Three recent examples of these viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus. keywords: acute; cases; cells; china; clinical; coronavirus; cov-2; covid-19; disease; health; human; infection; influenza; mers; ncov; novel; novel coronavirus; patients; pneumonia; protein; r n; responses; sars; study; syndrome; treatment; use; vaccine; wuhan cache: cord-286683-mettlmhz.txt plain text: cord-286683-mettlmhz.txt item: #61 of 178 id: cord-286854-0s7oq0uv author: Jin, Xi title: Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site date: 2020-07-03 words: 6027 flesch: 49 summary: Further comparative alignment analysis of GZ02 (SARS viral strain), Wuhan-Hu-1 (the earliest sequenced SARS-CoV-2), RaTG13, HKU9-1 (the potential ancestor of SARS and SARS-CoV-2), HKU-1 and OC43 showed that the variation of FCS sequence had certain regularity in coronavirus evolution ( Figure 4(B) ). Phylogenetic analysis suggested that SARS, RATG13, and SARS-CoV-2 exhibited remarkable evolutionary divergence, with potential evolutionary branches within SARS-CoV-2 ( Figure 1(A) ). keywords: cell; coronavirus; cov-2; covid-19; expression; fcs; furin; protein; sars; site; wuhan; zj01 cache: cord-286854-0s7oq0uv.txt plain text: cord-286854-0s7oq0uv.txt item: #62 of 178 id: cord-287222-wojyisu0 author: Zhou, Min title: Coronavirus disease 2019 (COVID-19): a clinical update date: 2020-04-02 words: 5692 flesch: 34 summary: Unlike influenza pneumonia, which usually exhibited unilateral GGO and significant solid nodules, only 6% of COVID-19 patients had solid nodules A majority of COVID-19 patients showed normal leucocyte count, and nearly one third had leucopenia keywords: china; clinical; coronavirus; covid-19; disease; infection; novel; patients; plasma; pneumonia; sars; study; syndrome; treatment; ventilation cache: cord-287222-wojyisu0.txt plain text: cord-287222-wojyisu0.txt item: #63 of 178 id: cord-287499-zcizdc7s author: Thompson, Hayley A title: SARS-CoV-2 infection prevalence on repatriation flights from Wuhan City, China date: 2020-08-24 words: 1400 flesch: 32 summary: Therefore, prevalence from repatriated flights can be considered a conservative estimate of infection prevalence in the wider population. Although not representative of the wider population we believe these estimates are helpful in providing a conservative estimate of infection prevalence in Wuhan City, China, in the absence of large-scale population testing early in the epidemic. keywords: flights; infection; prevalence; wuhan cache: cord-287499-zcizdc7s.txt plain text: cord-287499-zcizdc7s.txt item: #64 of 178 id: cord-287515-oe7adj91 author: Rello, Jordi title: Coronavirus Disease 2019 (COVID-19): A critical care perspective beyond China date: 2020-03-03 words: 1385 flesch: 38 summary: However, as many patients can remain asymptomatic or with very low symptomatology and because criteria of hospital admission were not standardised, the proportion of patients requiring supportive techniques for hypoxemia is probably lower. Our colleagues in Wuhan, who placed their lives at risk by treating patients with COVID-19, recently reported their experience in a scenario of crisis management with limited resources [1] . keywords: coronavirus; covid-19; influenza; patients; pneumonia cache: cord-287515-oe7adj91.txt plain text: cord-287515-oe7adj91.txt item: #65 of 178 id: cord-288432-n2y9cunc author: Liu, Kun title: Population movement, city closure in Wuhan and geographical expansion of the 2019-nCoV pneumonia infection in China in January 2020 date: 2020-04-17 words: 2372 flesch: 45 summary: The net loss index of outflow population caused by advanced Wuhan city closure for each province: 11 A c c e p t e d M a n u s c r i p t 10 Similarly, we evaluated the impacts of one-day and two-day delayed city closure. METHODS: Based on the daily reported new cases and the population movement data between January 1 and 31, we examined the effects of population outflow from Wuhan on the geographical expansion of the infection in other provinces and cities of China, as well as the impacts of the city closure in Wuhan in different scenarios of closing dates. keywords: cases; china; p t; population; wuhan cache: cord-288432-n2y9cunc.txt plain text: cord-288432-n2y9cunc.txt item: #66 of 178 id: cord-288616-7i1kukmn author: Wan, Kelvin H. title: The end of cordon sanitaire in Wuhan: the role of non-pharmaceutical interventions date: 2020-05-14 words: 1176 flesch: 48 summary: 10 Report of the WHO-China Joint Mission on Coronavirus Disease Early dynamics of transmission and control of COVID-19: a mathematical modelling study Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany The updates on COVID-19 in Korea as of Respiratory virus shedding in exhaled breath and efficacy of face masks The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in 8 China: a modelling study. In contrast, citizens are advised to wear facemask only when they are ill in most non-Asian countries. keywords: china; covid-19; health; public cache: cord-288616-7i1kukmn.txt plain text: cord-288616-7i1kukmn.txt item: #67 of 178 id: cord-289322-5ciaonf0 author: Chen, X. title: Epidemiological and clinical features of 291 cases with coronavirus disease 2019 in areas adjacent to Hubei, China: a double-center observational study date: 2020-03-06 words: 3874 flesch: 52 summary: key: cord-289322-5ciaonf0 authors: Chen, X.; Zheng, F.; Qing, Y.; Ding, S.; Yang, D.; Lei, C.; Yin, Z.; Zhou, X.; Jiang, D.; Zuo, Q.; He, J.; Lv, J.; Chen, P.; Chen, Y.; Peng, H.; Li, H.; Xie, Y.; Liu, J.; Zhou, Z.; Luo, H. title: Epidemiological and clinical features of 291 cases with coronavirus disease 2019 in areas adjacent to Hubei, China: a double-center observational study date: 2020-03-06 journal: nan DOI: 10.1101/2020.03.03.20030353 sha: doc_id: 289322 cord_uid: 5ciaonf0 Abstract Background: The clinical outcomes of COVID-19 patients in Hubei and other areas are different. Interpretation: The epidemiological and clinical characteristics of COVID-19 patients in Hunan is different from patients in Wuhan. keywords: clinical; covid-19; group; patients; preprint; study; wuhan cache: cord-289322-5ciaonf0.txt plain text: cord-289322-5ciaonf0.txt item: #68 of 178 id: cord-289451-yjrh5l4u author: Xiao, Huidi title: Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities date: 2020-07-14 words: 4720 flesch: 45 summary: We studied the associations between COVID-19 distancing and the lives of public health students on anxiety [14] , depression, and other behaviors. We also examined the differences among public health students in two universities, Capital Medical University (CCMU) in Beijing, and Huazhong University of Science and Technology (HUST) in Wuhan, the early epicenter of the COVID-19 outbreak in China. keywords: anxiety; covid-19; depression; disorder; health; medical; students; survey; wuhan cache: cord-289451-yjrh5l4u.txt plain text: cord-289451-yjrh5l4u.txt item: #69 of 178 id: cord-290758-kz0qfy3r author: Hui, David S. title: The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China date: 2020-02-29 words: 1317 flesch: 39 summary: Once there is any clue to the source of animals being responsible for this outbreak, global public health authorities should examine the trading route and source of movement of animals or products taken from the wild or captive conditions from other parts to Wuhan and consider appropriate trading restrictions or other control measures to limit. key: cord-290758-kz0qfy3r authors: Hui, David S.; I Azhar, Esam; Madani, Tariq A.; Ntoumi, Francine; Kock, Richard; Dar, Osman; Ippolito, Giuseppe; Mchugh, Timothy D.; Memish, Ziad A.; Drosten, Christian; Zumla, Alimuddin; Petersen, Eskild title: The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China date: 2020-02-29 journal: International Journal of Infectious Diseases DOI: 10.1016/j.ijid.2020.01.009 sha: doc_id: 290758 cord_uid: kz0qfy3r nan The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health -The latest 2019 novel coronavirus outbreak in Wuhan, China The city of Wuhan in China is the focus of global attention due to an outbreak of a febrile respiratory illness due to a coronavirus 2019-nCoV. In December 2019, there was an outbreak of pneumonia of unknown cause in Wuhan, Hubei province in China, with an epidemiological link to the Huanan Seafood Wholesale Market where there was also sale of live animals. keywords: 2019; health; ncov; novel cache: cord-290758-kz0qfy3r.txt plain text: cord-290758-kz0qfy3r.txt item: #70 of 178 id: cord-291583-1nxfh9yt author: Zhou, Hongmei title: Understanding the current status of patients with pulmonary hypertension during COVID-19 outbreak: a small-scale national survey from China date: 2020-05-18 words: 3368 flesch: 49 summary: Pulmonary hypertension patients need persistent medical care; however, limited reports focused on them when there was an outbreak of coronavirus disease 2019 in China. This national survey was aimed to evaluate the overall condition of pulmonary hypertension patients during this period. keywords: hypertension; participants; patients cache: cord-291583-1nxfh9yt.txt plain text: cord-291583-1nxfh9yt.txt item: #71 of 178 id: cord-292144-jprbp1ua author: Song, Haitao title: Using traveller-derived cases in Henan Province to quantify the spread of COVID-19 in Wuhan, China date: 2020-08-04 words: 3875 flesch: 52 summary: [8] estimated the number of cases in Wuhan city by 18th January. μ (b) is μ 1 (b 1 ) before January 23 and 0 after January 23 because that Wuhan city travel was banned on January 23. keywords: cases; covid-19; january; people; province; wuhan cache: cord-292144-jprbp1ua.txt plain text: cord-292144-jprbp1ua.txt item: #72 of 178 id: cord-292537-9ra4r6v6 author: Liu, Fenglin title: Predicting and analyzing the COVID-19 epidemic in China: Based on SEIRD, LSTM and GWR models date: 2020-08-27 words: 5675 flesch: 47 summary: Among them, the number of confirmed cases was the mostly used and reflected the severity of COVID-19 epidemic. The average percent error of LSTM model predictions for the four selected provinces and cities was within ±1.0% on February 14 th (Table 5) . keywords: cases; china; coronavirus; covid-19; data; epidemic; model; number; rate; study; wuhan cache: cord-292537-9ra4r6v6.txt plain text: cord-292537-9ra4r6v6.txt item: #73 of 178 id: cord-293831-28ddm9um author: Qian, Mengcen title: Psychological responses, behavioral changes and public perceptions during the early phase of the COVID-19 outbreak in China: a population based cross-sectional survey date: 2020-02-20 words: 4857 flesch: 47 summary: 11, 12, 13 Cultural differences are evident in public responses. Our study provides new evidence on psychological and behavioral response to disease outbreaks by comparing public response in two cities under various exposures to the early All rights reserved. keywords: anxiety; coronavirus; medrxiv; outbreak; participants; preprint; shanghai; wuhan cache: cord-293831-28ddm9um.txt plain text: cord-293831-28ddm9um.txt item: #74 of 178 id: cord-294333-6azdm42x author: Wang, S title: Sleep disturbances among medical workers during the outbreak of COVID-2019 date: 2020-05-06 words: 3012 flesch: 48 summary: We observed that, during the outbreak of COVID-19, sleep disturbance was highly prevalent among paediatric healthcare workers, and sleep disturbance was independently associated with being an only child, exposure to COVID-19 patients and depression. Paediatric healthcare workers also experience great work pressure. keywords: covid-19; depression; disturbance; healthcare; sleep; workers cache: cord-294333-6azdm42x.txt plain text: cord-294333-6azdm42x.txt item: #75 of 178 id: cord-294385-6dlgv3tb author: Tong, Xin title: Surveillance of SARS‐CoV‐2 infection among frontline health care workers in Wuhan during COVID‐19 outbreak date: 2020-08-20 words: 1381 flesch: 53 summary: During their stay in Wuhan, these HCWs stayed in the contaminated area every 4 h/d, including performing aerosol-generating procedures, collecting or handling specimens, providing care for COVID-19 patients, and sharing conversations with COVID-19 patient within a one-meter reach. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19)-China Serum samples from control HCWs without COVID-19 exposure were served as a negative control (n = 112). keywords: cov-2; hcws; infection; sars cache: cord-294385-6dlgv3tb.txt plain text: cord-294385-6dlgv3tb.txt item: #76 of 178 id: cord-294810-mq9vjnro author: Huang, Qiong title: Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China date: 2020-05-14 words: 3441 flesch: 49 summary: Severe COVID-19 patients present with any of the following: (1) shortness of breath, plus respiratory rate ≥ 30 breaths/min, (2) in resting state, oxygen saturation (SpO2) ≤ 93%, and 3) arterial partial pressure of oxygen (PaO2)/Fraction of inspiration oxygen (FiO2) ≤ 300 mmHg. Objective The study was aimed to describe the clinical characteristics, laboratory parameters, and therapeutic methods of COVID-19 patients in Hunan, China. keywords: coronavirus; covid-19; disease; patients; study; symptoms; treatment; type; wuhan cache: cord-294810-mq9vjnro.txt plain text: cord-294810-mq9vjnro.txt item: #77 of 178 id: cord-295386-voeptwrw author: Liu, J. title: Analysis of Collective Response Reveals that COVID-19-Related Activities Start From the End of 2019 in Mainland China date: 2020-10-16 words: 6166 flesch: 59 summary: The entire set of abnormal trends fits perfectly with the developing situation of the second wave of the pandemic, indicating the close-knit relationship between search trends and epidemic circumstances and the effectiveness of using search volume data as tools for exploring public reactions. Using search index data, we analyze correlations between the frequent search keywords, related to respiratory diseases, per day and the trends of confirmed cases using DTW and DCCA. keywords: author; funder; medrxiv; medrxiv preprint; perpetuity; preprint; search cache: cord-295386-voeptwrw.txt plain text: cord-295386-voeptwrw.txt item: #78 of 178 id: cord-296182-hhswage4 author: Meng, Lingzhong title: Intubation and Ventilation amid the COVID-19 Outbreak: Wuhan’s Experience date: 2020-04-08 words: 6539 flesch: 37 summary: Ventilator management for hypoxemic respiratory failure attributable to H1N1 novel swine origin influenza virus High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome Nursing and infection-control issues during high-frequency oscillatory ventilation Work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndrome: A comparison between volume and pressure-regulated breathing modes Ventilator management for acute respiratory distress syndrome associated with avian influenza A (H7N9) virus infection: A case series Prone positioning in severe acute respiratory distress syndrome Lung recruitment maneuvers for ARDS patients: A systematic review and meta-analysis Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation ACURASYS Study Investigators: Neuromuscular blockers in early acute respiratory distress syndrome Early neuromuscular blockade in the acute respiratory distress syndrome Neuromuscular blockade in acute respiratory distress syndrome: A systematic review and meta-analysis of randomized controlled trials ESICM H1N1 Registry Contributors: Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection Corticosteroids as adjunctive therapy in the treatment of influenza Corticosteroids as adjunctive therapy in the treatment of influenza: An updated Cochrane systematic review and meta-analysis González-Martín JM; dexamethasone in ARDS network: Dexamethasone treatment for the acute respiratory distress syndrome: A multicentre, randomised controlled trial Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome Extracorporeal life support: The next step in moderate to severe ARDS-A review and meta-analysis of the literature Elbourne D; CESAR trial collaboration: Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): A multicentre randomised controlled trial Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and posterior probability of mortality benefit in a post hoc Bayesian analysis of a randomized clinical trial A novel coronavirus outbreak of global health concern A review of isolation gowns in healthcare: Fabric and gown properties Prone position for acute respiratory distress syndrome. Approximately 3.2% of patients with COVID-19 required intubation and invasive ventilation at some point in the disease course. keywords: airway; china; covid-19; infection; intubation; lung; oxygenation; patients; pressure; syndrome; ventilation; wuhan cache: cord-296182-hhswage4.txt plain text: cord-296182-hhswage4.txt item: #79 of 178 id: cord-297168-t6zf5k99 author: Brüssow, Harald title: The Novel Coronavirus – A Snapshot of Current Knowledge date: 2020-03-06 words: 4151 flesch: 45 summary: Therapeutics directed against immunopathological host responses might have a treatment value in view of the 'cytokine storm' seen in some patients with novel coronavirus infections. Vaccines against MERS and SARS are currently not available. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Epidemiologic and clinical characteristics of novel coronavirus infections involving 13 patients Outside Wuhan, China Protecting health-care workers from subclinical coronavirus infection Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study A new transmission route for the propagation of the SARS-CoV-2 coronavirus. keywords: china; chinese; coronavirus; epidemic; market; novel; patients; sars; wuhan cache: cord-297168-t6zf5k99.txt plain text: cord-297168-t6zf5k99.txt item: #80 of 178 id: cord-297470-lx3xwg92 author: Pan, Yunbao title: Seroprevalence of SARS-CoV-2 immunoglobulin antibodies in Wuhan, China: part of the city-wide massive testing campaign date: 2020-10-07 words: 1602 flesch: 43 summary: Most of Wuhan residents are still susceptible to this virus. A recent study detected 17,368 individuals from different geographic regions in China, including 1993 residents from different Wuhan sub-cohorts. keywords: cov-2; igm; sars; study; wuhan cache: cord-297470-lx3xwg92.txt plain text: cord-297470-lx3xwg92.txt item: #81 of 178 id: cord-297552-n4uvsi3v author: Zou, Li title: Clinical Characteristics and Risk Factors for Disease Severity and Death in Patients With Coronavirus Disease 2019 in Wuhan, China date: 2020-08-13 words: 3440 flesch: 49 summary: Especially, the incidence of hypertension, cardiovascular and cerebrovascular diseases, and chronic pulmonary diseases in severe cases were significantly higher than that in non-severe cases (all P < 0.05). The differences in laboratory findings between non-severe cases and severe cases, as well as survivors and non-survivors Table 3 . keywords: cases; covid-19; disease; non; patients; study cache: cord-297552-n4uvsi3v.txt plain text: cord-297552-n4uvsi3v.txt item: #82 of 178 id: cord-298563-346lwjr8 author: Kaplan, Edward H. title: Containing 2019-nCoV (Wuhan) coronavirus date: 2020-03-07 words: 2300 flesch: 44 summary: Starting with case isolation, suppose that an infected person is detected at time T D days following infection, and is isolated for τ This note presents probability models for assessing the effectiveness of case isolation and quarantine within a community during the initial phase of an outbreak with illustrations based on early observations from Wuhan. keywords: infections; isolation; person; quarantine; time cache: cord-298563-346lwjr8.txt plain text: cord-298563-346lwjr8.txt item: #83 of 178 id: cord-298857-4y5o2p44 author: Zhu, Jie title: Engaging the communities in Wuhan, China during the COVID-19 outbreak date: 2020-07-13 words: 1717 flesch: 50 summary: Community governance systems (CGSs) were mobilized to lead community engagement to address the challenges and issues brought about by the sudden quarantine measures, still unprecedented in any part of the world during that time. The grassroots unit of government plays a role in community governance. keywords: cgss; community; covid-19; cpc cache: cord-298857-4y5o2p44.txt plain text: cord-298857-4y5o2p44.txt item: #84 of 178 id: cord-298881-u6uqroi0 author: Huang, Ian title: Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia – A systematic review, meta-analysis, and meta-regression() date: 2020-04-17 words: 3162 flesch: 43 summary: The authors declared no conflict of interest Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Diabetes is a risk factor for the progression and prognosis of COVID-19 COVID-19 and diabetes Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Report of the WHO-China Joint Mission on Coronavirus Disease 2019 ( COVID-19 ) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical features and outcomes of 221 patients with COVID-19 in Wuhan Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China Clinical Features and Treatment of COVID-19 Patients in Northeast Chongqing Platelet-to-lymphocyte ratio is associated with prognosis in patients with Corona Virus Disease-19 Dysregulation of immune response in patients with COVID-19 in Wuhan, China Clinical Characteristics of Patients with Severe Pneumonia Caused by the 2019 Novel Coronavirus in Wuhan Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics Clinical characteristics of 51 patients discharged from hospital with COVID-19 in Chongqing，China Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients COVID-19 in a Designated Infectious Diseases HospitalOutside Hubei Province Neutrophil-to-Lymphocyte Ratio Predicts Severe Illness Patients with 2019 Novel Coronavirus in the Early Stage Non-severe vs severe symptomatic COVID-19: 104 cases from the outbreak on the cruise ship Clinical Characteristics And Risk Factors For Fatal Outcome in Patients With 2019-Coronavirus Infected Disease (COVID-19) in Wuhan Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical Features of Patients Infected with the 2019 Novel Coronavirus (COVID-19 Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019 Clinical Characteristics of Coronavirus Disease 2019 in China Analysis of factors associated with disease outcomes in hospitalized patients with Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China Radiographic Findings and other Predictors in Adults with Covid-19 Analysis of Death Risk Factors Among 200 COVID-19 Patients in Wuhan, China: A Hospital-Based Case-Cohort Study Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan Clinical Characteristics of SARS-CoV-2 Infections Involving 325 Hospitalized Patients outside Wuhan Epidemiological Characteristics of 417 patients infected with COVID-19 and 368 discharged cases among them in Shenzhen City Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of China: a descriptive study COVID-19, diabetes mellitus and ACE2: The conundrum The Effect of Short-Term Hyperglycemia on the Innate Immune System Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type 1 diabetes rats Contentious issues and evolving concepts in the clinical presentation and management of patients with COVID-19 infectionwith reference to use of therapeutic and other drugs used in Co-morbid diseases (Hypertension, diabetes etc) Angiotensin-converting enzyme 2 protects from severe acute lung failure The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Immune dysfunction in patients with diabetes mellitus (DM) COVID-19: consider cytokine storm syndromes and immunosuppression ≤40 (53%) CAD: [1] Although the majority of COVID-19 patients present with mild or no symptoms, some patients will develop severe pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, and death. keywords: analysis; covid-19; disease; meta; outcome; patients cache: cord-298881-u6uqroi0.txt plain text: cord-298881-u6uqroi0.txt item: #85 of 178 id: cord-298899-lkrmg5qr author: Xie, Yewei title: Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis date: 2020-08-31 words: 6251 flesch: 50 summary: Download today's data on geographic distribution of COVID-19 cases worldwide Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study Ethnicity and COVID-19: an urgent public health research priority COVID-19 sex-disaggregated data tracker-Sex, gender and COVID-19 Clinical features and outcomes of 98 patients hospitalized with SARS-CoV-2 infection in Daegu, South Korea: a brief descriptive study Early epidemiological and clinical manifestations of COVID-19 in Japan Clinical, radiological and therapeutic characteristics of patients with COVID-19 in Saudi Arabia Clinical course and potential predicting factors of pneumonia of adult patients with coronavirus disease 2019 (COVID-19): a retrospective observational analysis of 193 confirmed cases in Thailand Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO clinical characterization protocol: prospective observational cohort study Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 network Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia Clinical and epidemiological characteristics of patients diagnosed with COVID-19 in a tertiary care center in Mexico CITY: a prospective cohort study Early experience with COVID-19 patients at academic hospital in southwestern United States Clinical characteristics and morbidity associated with coronavirus disease 2019 in a series of patients in metropolitan Detroit Clinical characteristics of Covid-19 in New York city Epidemiological and clinical characteristics of the early phase of the COVID-19 epidemic in Brazil Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study Utility of hyposmia and hypogeusia for the diagnosis of COVID-19 Selfreported olfactory and taste disorders in patients with severe acute respiratory coronavirus 2 infection: a cross-sectional study COVID-19 anosmia reporting tool: initial findings Features of anosmia in COVID-19 Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Smell dysfunction: a biomarker for COVID-19. In the US for example, the reasons that turned hospitals into infection hotspots included the overload of COVID-19 patients and inappropriate management against the pandemic in hospitals [29] . keywords: cases; characteristics; china; clinical; coronavirus; cov-2; covid-19; data; disease; novel; patients; sars; study; transmission cache: cord-298899-lkrmg5qr.txt plain text: cord-298899-lkrmg5qr.txt item: #86 of 178 id: cord-299584-zpiaka80 author: Biscayart, Cristian title: The next big threat to global health? 2019 novel coronavirus (2019-nCoV): What advice can we give to travellers? – Interim recommendations January 2020, from the Latin-American society for Travel Medicine (SLAMVI) date: 2020-02-29 words: 2307 flesch: 50 summary: Remarkably, WHO has reported that in the last one week, less than 15% of new cases reported had visited the Huanan market. Some cases need hospitalization due to the worsening of the clinical status and in several cases, the complications could lead to death keywords: cases; china; coronavirus; health; human; ncov; outbreak; wuhan cache: cord-299584-zpiaka80.txt plain text: cord-299584-zpiaka80.txt item: #87 of 178 id: cord-301633-t8s4s0wo author: Gralinski, Lisa E. title: Return of the Coronavirus: 2019-nCoV date: 2020-01-24 words: 4001 flesch: 47 summary: Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2 Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1 Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission Functional assessment of cell entry and receptor usage for lineage B β-coronaviruses, including 2019-nCoV Viruses and Koch's Postulates A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4 Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques 15 Medical Staff in Wuhan Confirmed New Coronavirus Pneumonia, and Another Suspected Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review The Role of Super-Spreaders in Infectious Disease Analysis of intrapatient heterogeneity uncovers the microevolution of Middle East respiratory syndrome coronavirus No Snakes Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence SARS-like WIV1-CoV poised for human emergence Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus Identification of a severe acute respiratory syndrome coronavirus-like virus in a leaf-nosed bat in Nigeria Evidence for camel-to-human transmission of MERS coronavirus Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study Risk Factors for Fatal Middle East Respiratory Syndrome Coronavirus Infections in Saudi Arabia: Analysis of the WHO Line List Severe Acute Respiratory Syndrome Preliminary Phylogenetic Analysis of 11 nCoV2019 Genomes Genomic Epidemiology of Novel Coronavirus (nCoV) Using Data Generated by Fudan University, China CDC, Chinese Academy of Medical Sciences, Chinese Academy of Sciences and the Thai National Institute of Health Shared via GISAID Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin Jumping species-a mechanism for coronavirus persistence and survival keywords: 2019; cases; coronavirus; cov; health; human; mers; ncov; sars cache: cord-301633-t8s4s0wo.txt plain text: cord-301633-t8s4s0wo.txt item: #88 of 178 id: cord-301983-aks5z29t author: Vakili, K. title: Critical Complications of COVID-19: A systematic Review and Meta-Analysis study date: 2020-06-16 words: 3823 flesch: 49 summary: The most prevalent complications were acute respiratory distress syndrome (ARDS) 33.15% (95% CI: 23.35-43.73; I2=98.56%), acute cardiac injury 13.77% (95% CI: 9.66-18.45; I2=91.36%), arrhythmia 16.64% (95% CI: 9.34-25.5; I2=92.29%), heart failure 11.50% (95% CI: 3.45-22.83; I2=89.48%), and acute kidney injury (AKI) 8.40 %(95% CI: 5.15-12.31; I2=95.22%, respectively. According to our analysis, mortality rate of COVID-19 patients were 12.29% (95% CI: 6.20-19.99; I2=98.29%). keywords: analysis; clinical; complications; covid-19; patients; studies cache: cord-301983-aks5z29t.txt plain text: cord-301983-aks5z29t.txt item: #89 of 178 id: cord-302159-exexcag6 author: Wei, Yanqiu title: Analysis of 2019 novel coronavirus infection and clinical characteristics of outpatients: An epidemiological study from a fever clinic in Wuhan, China date: 2020-06-16 words: 3059 flesch: 43 summary: In terms of age distribution, the average age for the diagnosed COVID-19 patients was 53 years (±14.8 years), while the average age for nucleic acid negative patients was 49 years (±13.0 years), which was significantly younger than that of COVID-19 patients (P < 0.01). Among all 936 visitors, 460 of them conducted routine blood tests, and 309 were COVID-19 patients, while the rests were nucleic acid negative patients. keywords: acid; covid-19; fever; patients; sars; wuhan cache: cord-302159-exexcag6.txt plain text: cord-302159-exexcag6.txt item: #90 of 178 id: cord-303203-1kpw4ru0 author: Guo, Jing title: Coping with COVID-19: Exposure to COVID-19 and Negative Impact on Livelihood Predict Elevated Mental Health Problems in Chinese Adults date: 2020-05-29 words: 4493 flesch: 45 summary: Mental health problems were assessed with the Post-Traumatic Stress Disorders (PTSD) Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), the Center for Epidemiological Studies Depression inventory, and the Pittsburgh Sleep Quality Index. Perceived negative impact of the pandemic on livelihood showed a large effect size in predicting mental health problems (standardized beta: 0.15, 95% CI: 0.10–0.19). keywords: behaviors; covid-19; exposure; health; impact; livelihood; pandemic; problems cache: cord-303203-1kpw4ru0.txt plain text: cord-303203-1kpw4ru0.txt item: #91 of 178 id: cord-303799-9hh17k86 author: Huang, Ying title: Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China date: 2020-02-29 words: 2802 flesch: 56 summary: In our cohort, lymphocytopenia occurred in more than 70% of patients at admission, which is a main laboratory feature in COVID-19 patients 15, 17 . Patients had common clinical symptoms of fever (34 [94.44%] patients), cough (28 [77.78%] patients), shortness of breath (21 [58.33%] patients), and fatigue (17 [47.22%] patient). keywords: covid-19; medrxiv; patients; preprint; study cache: cord-303799-9hh17k86.txt plain text: cord-303799-9hh17k86.txt item: #92 of 178 id: cord-304165-4f84pc83 author: Zhuang, Zian title: Estimation of local novel coronavirus (COVID-19) cases in Wuhan, China from off-site reported cases and population flow data from different sources date: 2020-03-02 words: 2513 flesch: 54 summary: From separate cities/regions data, we estimated 1059 (95% CI: 918, 1209), 5214 (95% CI: 4659, 5808) as total cases in Wuhan in Wuhan by 23 January 2020, based on different sources of population flow data from Tencent and Baidu. We predicted 1059 (95% CI: 918, 1209), 5214 (95% CI: 4659, 5808) as total cases in Wuhan by 23 January 2020, based on different sources of population flow data, see Table 2 . . keywords: cases; data; license; preprint; wuhan cache: cord-304165-4f84pc83.txt plain text: cord-304165-4f84pc83.txt item: #93 of 178 id: cord-304418-k9owyolj author: Le Maréchal, M. title: COVID-19 in clinical practice: a narrative synthesis date: 2020-09-29 words: 6303 flesch: 43 summary: Thromboembolic complications Several works have described the high incidence in COVID-19 patients of both venous and arterial thromboembolic diseases. Cardiac injuries have been described in COVID-19 patients. keywords: cases; china; coronavirus; covid-19; days; disease; group; infection; patients; remdesivir; sars; study; syndrome; treatment; viral cache: cord-304418-k9owyolj.txt plain text: cord-304418-k9owyolj.txt item: #94 of 178 id: cord-304490-q9ab1pji author: Iqbal, Najaf title: Nexus between COVID-19, temperature and exchange rate in Wuhan City: New findings from Partial and Multiple Wavelet Coherence date: 2020-04-22 words: 3774 flesch: 47 summary: In this uncertain situation where literature is inconclusive about the role of temperature in the covid-19 spread, we attempt to analyze the number of daily new covid-19 cases and average daily temperature in this regard. Weather is found to be associated with the daily number of covid-19 cases in the Indonesian capital city of Jakarta also (Tosepu et al., 2020) . keywords: coherence; covid-19; exchange; rate; temperature; wavelet; wuhan cache: cord-304490-q9ab1pji.txt plain text: cord-304490-q9ab1pji.txt item: #95 of 178 id: cord-304710-gjb6zo81 author: Khan, S. title: Novel coronavirus: how things are in Wuhan date: 2020-02-11 words: 1372 flesch: 48 summary: The latest 2019 novel coronavirus outbreak in Wuhan, China Coronavirus claims first life outside China as Wuhan enforces quarantine for all suspected patients China coronavirus: Wuhan medical staff being infected at much faster pace than reported as national death toll hits 26 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Wuhan calls for more material help to deal with virus. A total of 15 medical staff have been infected, and one doctor has died from 2019n-CoV infection in Wuhan hospital keywords: medical; patients; staff; wuhan cache: cord-304710-gjb6zo81.txt plain text: cord-304710-gjb6zo81.txt item: #96 of 178 id: cord-304839-lesa5u2n author: Jiang, Fang title: Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) date: 2020-03-04 words: 1908 flesch: 51 summary: cn/showprojen.aspx?proj=48684 Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Baricitinib as potential treatment for 2019-nCoV acute respiratory disease After careful screening, six published articles with confirmed cases were identified and included in this review. keywords: 2019; coronavirus; novel cache: cord-304839-lesa5u2n.txt plain text: cord-304839-lesa5u2n.txt item: #97 of 178 id: cord-304925-9gvx3swf author: Xie, Zhixiang title: Spatial and temporal differentiation of COVID-19 epidemic spread in mainland China and its influencing factors date: 2020-07-14 words: 4777 flesch: 34 summary: Liu et al. (2020c) used the statistical analysis method to analyze the temporal and spatial J o u r n a l P r e -p r o o f characteristics and the transmission path of the COVID-19 epidemic in Zhuhai, revealing that the input from the epidemic area and family gatherings were the causes of epidemic spread. (4) In relation to data sources, the data of COVID-19 cases can be obtained very easily; however, there are great difficulties in obtaining environmental and socio-economic data related to the epidemic spread, which is why current researches lag behind in the driving J o u r n a l P r e -p r o o f mechanism of epidemic spread. keywords: covid-19; epidemic; epidemic spread; factors; population; rate; spread cache: cord-304925-9gvx3swf.txt plain text: cord-304925-9gvx3swf.txt item: #98 of 178 id: cord-305054-4d84b2g6 author: Liu, Yuan title: The selection of reference genome and the search for the origin of SARS-CoV-2 date: 2020-08-11 words: 2176 flesch: 56 summary: key: cord-305054-4d84b2g6 authors: Liu, Yuan; Yan, Changhui title: The selection of reference genome and the search for the origin of SARS-CoV-2 date: 2020-08-11 journal: bioRxiv DOI: 10.1101/2020.08.10.245290 sha: doc_id: 305054 cord_uid: 4d84b2g6 We investigated how the selection of reference genome affect the resulting CoV genome assembly. keywords: genome; hu-1; ratg13; reference cache: cord-305054-4d84b2g6.txt plain text: cord-305054-4d84b2g6.txt item: #99 of 178 id: cord-305213-bt0qsbyf author: Zhou, Jian title: Epidemiological and clinical features of 201 COVID-19 patients in Changsha city, Hunan, China date: 2020-08-21 words: 2686 flesch: 44 summary: The occupational composition of the ICU group differed from the non-ICU group, and the number of patients exposed to Wuhan city in the ICU group was significantly higher than that of the non-ICU group, which indicates that the exposure history to Wuhan city may affect the outcome of COVID-19 patients. Patients in the ICU group must breathe more frequently to provide the oxygen required compared to patients in the non-ICU group. keywords: changsha; covid-19; group; icu; patients; study; wuhan cache: cord-305213-bt0qsbyf.txt plain text: cord-305213-bt0qsbyf.txt item: #100 of 178 id: cord-305422-t8azymo7 author: Yi, Ye title: COVID-19: what has been learned and to be learned about the novel coronavirus disease date: 2020-03-15 words: 8317 flesch: 47 summary: In SARS patients, it has been demonstrated that fever (99%-100%), dry cough (29%-75%), dyspnea (40%-42%), diarrhea (20-25%), and sore throat (13-25%) were the major symptoms and ventilation support was required for approximately 14%-20% of the patients [45] . Cardiac events were also the main reason for death in SARS patients [55, 65, 99] . keywords: acute; cases; china; coronavirus; cov-2; covid-19; disease; human; infection; mers; novel; outbreak; patients; sars; study; syndrome; treatment cache: cord-305422-t8azymo7.txt plain text: cord-305422-t8azymo7.txt item: #101 of 178 id: cord-306189-ugxou9z1 author: Bherwani, Hemant title: Valuation of air pollution externalities: comparative assessment of economic damage and emission reduction under COVID-19 lockdown date: 2020-06-10 words: 4610 flesch: 48 summary: Population for the years of valuation is estimated to evaluate the extent of health damages due to AP in a particular city. The daily mean of PM 2.5 , PM 10 and daily averages for NO 2 during the month of lockdown days in 2020 and the same month for the previous year 2019 was found beyond the acceptable limit, thereby health damage assessment is carried out by certain set of formulas (Eqs. (1)- (3)) keywords: air; cities; damages; health; lockdown; morbidity; mortality; table cache: cord-306189-ugxou9z1.txt plain text: cord-306189-ugxou9z1.txt item: #102 of 178 id: cord-306373-61snvddh author: Xu, Xiao-Wei title: Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series date: 2020-02-19 words: 3596 flesch: 51 summary: Consequently, over time more patients are expected to emerge across China and perhaps the world. It is possible that an even greater number of infected patients exist without a diagnosis because their symptoms were less severe and because of the incubation period. keywords: cov-2; days; infection; patients; sars; study; symptoms; wuhan cache: cord-306373-61snvddh.txt plain text: cord-306373-61snvddh.txt item: #103 of 178 id: cord-306690-s5mxes4r author: Shangguan, Ziheng title: What Caused the Outbreak of COVID-19 in China: From the Perspective of Crisis Management date: 2020-05-08 words: 8712 flesch: 47 summary: In public health crisis management, five factors are usually considered [21] The five commonly considered factors in public health crisis management are a useful framework to analyze the problems and major causes of the COVID-19 crisis in China. keywords: china; chinese; covid-19; crisis; crisis management; government; health; information; january; management; public; wuhan cache: cord-306690-s5mxes4r.txt plain text: cord-306690-s5mxes4r.txt item: #104 of 178 id: cord-309001-erm705tg author: Liu, Q. title: Laboratory findings and a combined multifactorial approach to predict death in critically ill patients with COVID-19: a retrospective study date: 2020-06-30 words: 3457 flesch: 48 summary: (1) Combination of predictors and development of predictive model Three laboratory indicators were combined to provide a predictive probability value for the outcome of death in COVID-19 patients, which was expressed in terms of PRE. The cohort study from Jin Yin-tan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) also found that DD greater than 1 μg/ml was the risk factor of death in COVID-19 patients. keywords: clinical; coronavirus; covid-19; death; disease; patients; study cache: cord-309001-erm705tg.txt plain text: cord-309001-erm705tg.txt item: #105 of 178 id: cord-309478-yhmgopmr author: Jin, Ying-Hui title: Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey date: 2020-05-11 words: 4565 flesch: 45 summary: Hence, this study aims to explore perceived infection routes, influencing factors, psychosocial changes, and management procedures for COVID-19 infected healthcare workers. key: cord-309478-yhmgopmr authors: Jin, Ying-Hui; Huang, Qiao; Wang, Yun-Yun; Zeng, Xian-Tao; Luo, Li-Sha; Pan, Zhen-Yu; Yuan, Yu-Feng; Chen, Zhi-Min; Cheng, Zhen-Shun; Huang, Xing; Wang, Na; Li, Bing-Hui; Zi, Hao; Zhao, Ming-Juan; Ma, Lin-Lu; Deng, Tong; Wang, Ying; Wang, Xing-Huan title: Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey date: 2020-05-11 journal: keywords: cases; covid-19; equipment; healthcare; hospital; infection; patients; staff; study; workers cache: cord-309478-yhmgopmr.txt plain text: cord-309478-yhmgopmr.txt item: #106 of 178 id: cord-309569-b9jcgx4s author: Lin, Qiu-Shi title: Further explanations for the eq. (3) in “Estimating the daily trend in the size of the COVID-19 infected population in Wuhan” date: 2020-09-15 words: 375 flesch: 62 summary: Since the window from infection to detection is assumed as d days in our model, the infected cases that left Wuhan before Day t − d should be confirmed outside Hubei province before Day t, thus this approximation is reasonable and would not affect the conclusion in the paper. In the Methods section, we let x t be the number of imported cases outside Hubei province on Day t, and derive a binomial model To make our model clearer, here x t is in fact the number of infected individuals that travelled from Wuhan to places outside Hubei province on Day t − d. keywords: wuhan cache: cord-309569-b9jcgx4s.txt plain text: cord-309569-b9jcgx4s.txt item: #107 of 178 id: cord-310676-125o0o7x author: Liu, Qibin title: Prediction of the clinical outcome of COVID-19 patients using T lymphocyte subsets with 340 cases from Wuhan, China: a retrospective cohort study and a web visualization tool date: 2020-04-11 words: 2813 flesch: 47 summary: As several other research teams pointed out, the potential risk factors of older age, high SOFA score, and d-dimer greater than 1 µg/L could help clinicians to identify patients with poor prognosis at an early stage 12 . Older patients (>65 years) with comorbidities and ARDS are at increased risk of death 14 . While age and underlying diseases are known risk factors for poor prognosis, patients with a less damaged immune system at the time of hospitalization had higher chance of recovery. keywords: coronavirus; covid-19; lymphocyte; patients; subsets; wuhan cache: cord-310676-125o0o7x.txt plain text: cord-310676-125o0o7x.txt item: #108 of 178 id: cord-311585-h4holhit author: Ling, R. title: Seroprevalence and epidemiological characteristics of immunoglobulin M and G antibodies against SARS-CoV-2 in asymptomatic people in Wuhan, China date: 2020-06-19 words: 3793 flesch: 45 summary: Other individuals with high IgG seroprevalence were easy to identify due to the nature of their jobs. Our study found significant differences in IgG seroprevalence among people going back to work by types of jobs, with the highest seroprevalence in volunteer medical examinees who came for tests without a mandate from their job supervisors. keywords: cov-2; covid-19; igg; igm; people; preprint; sars; seroprevalence cache: cord-311585-h4holhit.txt plain text: cord-311585-h4holhit.txt item: #109 of 178 id: cord-312399-7oaerpee author: Park, Joo-Hyun title: The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis date: 2020-05-01 words: 4658 flesch: 45 summary: However, some COVID-19 patients demonstrate no symptoms or complain of only gastrointestinal (GI) symptoms; furthermore, the clinical features of COVID-19 patients diagnosed outside of Wuhan, China differed from those of patients diagnosed in Wuhan [18] . The objectives of this study were to identify the clinical features and chest CT findings of COVID-19 patients and to compare the characteristics of patients diagnosed in Wuhan and in other areas by integrating the findings reported in previous studies. keywords: analysis; coronavirus; covid-19; disease; patients; studies; study; wuhan cache: cord-312399-7oaerpee.txt plain text: cord-312399-7oaerpee.txt item: #110 of 178 id: cord-314273-xhnv5cje author: Lytras, Theodore title: Estimating the ascertainment rate of SARS-CoV-2 infection in Wuhan, China: implications for management of the global outbreak date: 2020-03-26 words: 2139 flesch: 44 summary: On 12 February there was a spike of 13,436 retroactively reported confirmed cases due to a change in the case definition; we addressed this by linearly interpolating the new confirmed cases for that date and distributing the remainder to all previous dates in proportion to the number of cases already reported. We sought to estimate the ascertainment rate by applying epidemic modelling to publicly reported confirmed COVID-19 cases in Wuhan; a secondary objective was to estimate other epidemic parameters, including the basic reproduction number R0. keywords: ascertainment; medrxiv; preprint; rate; wuhan cache: cord-314273-xhnv5cje.txt plain text: cord-314273-xhnv5cje.txt item: #111 of 178 id: cord-314311-xbpb9nfi author: Ge, Huipeng title: The epidemiology and clinical information about COVID-19 date: 2020-04-14 words: 5298 flesch: 51 summary: Isolating virus from urine of the patient with novel coronavirus pneumonia Pattern of early human-to-human transmission of Wuhan Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a datadriven analysis in the early phase of the outbreak Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study The reproductive number of COVID-19 is higher compared to SARS coronavirus An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov) Middle East respiratory syndrome MERS coronavirus outbreak: implications for emerging viral infections MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2 First case of 2019 novel coronavirus in the United States CT imaging features of 2019 novel coronavirus (2019-nCoV). However, patients with SARS and MERS have more gastrointestinal involvement (about one-third) than COVID-19 patients [55] . keywords: china; clinical; coronavirus; cov-2; covid-19; disease; human; ncov; novel; patients; pneumonia; sars; wuhan cache: cord-314311-xbpb9nfi.txt plain text: cord-314311-xbpb9nfi.txt item: #112 of 178 id: cord-314591-ylokznn5 author: Quilty, Billy J. title: The effect of travel restrictions on the geographical spread of COVID-19 between large cities in China: a modelling study date: 2020-08-19 words: 5269 flesch: 49 summary: As recent studies have shown [8, 9, 33] , strict physical distancing measures soon decreased the effective reproduction number to 1 or less in Wuhan and other cities in China. By incorporating this decrease into our model, we find that cordon sanitaire alone, implemented after outbreaks were likely to be established in other cities, was likely ineffective in stopping or slowing outbreaks of COVID-19 in other major population centres. keywords: cities; cordon; covid-19; likely; number; sanitaire; transmission; travel; wuhan cache: cord-314591-ylokznn5.txt plain text: cord-314591-ylokznn5.txt item: #113 of 178 id: cord-315525-u8goc7io author: Backer, Jantien A. title: The incubation period of 2019-nCoV infections among travellers from Wuhan, China date: 2020-01-28 words: 1971 flesch: 51 summary: The estimated mean incubation periods for SARS are more variable between studies, including values shorter and longer than presented here for 2019-nCoV. These findings imply that findings of previous studies that have assumed incubation period distribution similar to MERS or SARS will not have to be adapted because of a shorter or longer incubation period. . In absence of data on the 2019-nCoV incubation period, the WHO has worked with a broad range of 0 to 14 days, the CDC has taken a range of 2 to 14 days, and several studies have assumed incubation periods of SARS or MERS coronaviruses. keywords: incubation; license; medrxiv; preprint cache: cord-315525-u8goc7io.txt plain text: cord-315525-u8goc7io.txt item: #114 of 178 id: cord-315598-qwh72inx author: Mendoza, Jose Luis Accini title: ACTUALIZACION DE LA DECLARACIÓN DE CONSENSO EN MEDICINA CRITICA PARA LA ATENCIÓN MULTIDISCIPLINARIA DEL PACIENTE CON SOSPECHA O CONFIRMACIÓN DIAGNÓSTICA DE COVID-19 date: 2020-10-06 words: 69660 flesch: 31 summary: y los que tienen menos probabilidades de beneficiarse (él «demasiado enfermo»), no prestan suficiente atención a las diferencias entre grupos en términos de la duración de los cuidados intensivos necesarios para lograr resultados. Se recomienda aplicar la escala SOFA al menos cada 48 horas sumado al criterio de fragilidad y años de vida saludables salvados estos criterios podrían ser válidos en pacientes con fallo terapéutico a las medidas óptimas y orientar decisiones de deescalamiento de medidas y de nivel de complejidad de atención cuando la demanda potencial supera la oferta (capacidad y capacidades), estas decisiones deben ser tomadas idealmente en junta médica. keywords: 2019; 2020; acuerdo con; acute; además de; aguda; alto; amci; analysis; análisis de; asociado con; aumento de; bajo; calidad de; care; casos de; clinical; clínica; clínica de; clínicos; comité de; como el; como la; como los; como se; como una; compromiso; con covid-19; con el; con enfermedad; con hipoxemia; con infección; con la; con los; con mayor; con neumonía; con que; con sars; con sdra; con sospecha; con su; con un; condiciones de; considerar la; contar con; contra; control; coronavirus; cov-2; criterios de; crítico con; cual se; cuando se; cuenta la; de acuerdo; de aerosoles; de alta; de amci; de atención; de baja; de cada; de contaminación; de coronavirus; de covid-19; de cuidados; de de; de dificultad; de enfermedad; de esta; de estos; de estudios; de falla; de forma; de hcq; de hipoxemia; de il-6; de infección; de ingreso; de intubación; de la; de los; de manera; de marzo; de menor; de oxígeno; de pacientes; de protección; de salud; de ser; de soporte; de su; de tórax; de un; de ventilación; de vida; deben; del; del virus; dentro; desde el; después de; diagnóstico de; disease; disminución de; disminuir el; disponibilidad de; distress; donde; dosis; dosis de; duración de; durante la; días; días de; el consentimiento; el cual; el de; el diagnóstico; el día; el estudio; el grupo; el inicio; el manejo; el momento; el más; el nivel; el número; el paciente; el pronóstico; el riesgo; el sars; el tiempo; el traslado; el uso; elevación de; embargo; en china; en contra; en cuenta; en el; en este; en la; en los; en salud; en su; en uci; en un; entre el; entre la; entre los; es una; estado de; este; estrategia de; está; evidencia de; evitar la; fin de; final de; fue de; fuera de; fueron; grupo de; hasta el; horas; infección por; inicio de; intensive; la administración; la capacidad; la cual; la decisión; la disponibilidad; la enfermedad; la evidencia; la falla; la hcq; la hipoxemia; la infección; la intubación; la mortalidad; la oxigenación; la pandemia; la presencia; la presión; la relación; la respuesta; la salud; la seguridad; la terapia; la toma; la uci; la utilización; la valoración; la vida; la vía; las; los casos; los cuales; los días; los estudios; los síntomas; luego de; manejo de; mayor; mayoría de; mecánica; medición de; medidas de; mejorar la; mejoría; menor; más de; necesidad de; nivel de; niveles; número de; o por; o se; objetivo de; otros; pacientes con; pacientes covid-19; pacientes críticos; pacientes que; pacientes y; para el; para la; para los; para pacientes; para que; para sars; para su; parte de; patients; pcr; pero; personal de; plasma; por covid-19; por el; por la; por los; por sars; por un; posibilidad de; presión; protocolo de; pueden; pulmonar; punto de; que; que el; que la; que los; que puede; que se; que una; realización de; realizar; recomendación se; recomienda la; recomienda que; reducción de; renal; respiratoria; resultados; retiro de; review; riesgo de; salud y; sars; se debe; se han; se puede; se recomienda; según la; ser; severa; severidad de; shock; si el; si la; si se; sin; sobre el; sobre la; son de; sospecha de; syndrome; síndrome de; tasa de; tener; tener en; teniendo en; tiempo de; tipo de; todos los; tormenta de; trabajadores de; tratamiento de; treatment; uci y; un estudio; un paciente; una; unidad de; uso de; utilizar; ventilation; viral; y al; y cols; y como; y con; y de; y el; y en; y es; y la; y los; y para; y por; y puede; y que; y se; y su; y una cache: cord-315598-qwh72inx.txt plain text: cord-315598-qwh72inx.txt item: #115 of 178 id: cord-316757-p370gjjn author: Kofi Ayittey, Foster title: Updates on Wuhan 2019 novel coronavirus epidemic date: 2020-02-10 words: 651 flesch: 36 summary: The Lancet Recent advances in the detection of respiratory virus infection in humans Emerging coronaviruses: genome structure, replication, and pathogenesis Chinese Researchers Reveal Draft Genome of Virus Implicated in Wuhan Pneumonia Outbreak A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-toperson transmission: a study of a family cluster. The Lancet Offline: 2019-nCoV outbreak-early lessons Global health concern stirred by emerging viral infections Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle Discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus Coronaviridae: the viruses and their replication Fields International Committee on Taxonomy of Viruses (ICTV) Coronavirus infections and immune responses Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. keywords: coronavirus; novel; wuhan cache: cord-316757-p370gjjn.txt plain text: cord-316757-p370gjjn.txt item: #116 of 178 id: cord-316990-kz9782rj author: Han, Xuehua title: Using Social Media to Mine and Analyze Public Opinion Related to COVID-19 in China date: 2020-04-17 words: 8492 flesch: 48 summary: The descriptive statistics of two variables (the number of Weibo texts In order to explore the correlation between public opinion and the epidemic situation, this study used Statistical Product and Service Solutions (SPSS Inc., Chicago, IL, USA) software to perform Spearman correlation analysis on the number of relevant Weibo texts and confirmed cases in provincial level (number is 34). Based on the latent Dirichlet allocation model and the random forest algorithm, a topic extraction and classification model was developed to hierarchically identify seven COVID-19-relevant topics and 13 sub-topics from Weibo texts. keywords: areas; beijing; capital; covid-19; figure; number; public; response; texts; topics; weibo; wuhan cache: cord-316990-kz9782rj.txt plain text: cord-316990-kz9782rj.txt item: #117 of 178 id: cord-317465-ucwuptgg author: FANG, H. title: Human Mobility Restrictions and the Spread of the Novel Coronavirus (2019-nCoV) in China date: 2020-03-26 words: 12105 flesch: 52 summary: Second, following the same strategy of Section 4.2, for a non-Wuhan city j in Hubei province, we use the within-city-j population movement at date t to proxy for the inflow to city j from city j when we implement Equation (5) for non-Wuhan Hubei cities. We also estimate the dynamic effects of up to 22 lagged population inflows from Wuhan and other Hubei cities, the epicenter of the 2019-nCoV outbreak, on the destination cities' new infection cases. keywords: cases; cities; city; effect; hubei; license; population; preprint; wuhan; wuhan lockdown cache: cord-317465-ucwuptgg.txt plain text: cord-317465-ucwuptgg.txt item: #118 of 178 id: cord-319770-ddq2q1pg author: Wen, Ying title: Epidemiological and clinical characteristics of COVID-19 in Shenzhen, the largest migrant city of China date: 2020-03-23 words: 3137 flesch: 43 summary: We conducted a retrospective study of the epidemiological and clinical characteristics of COVID-19 cases in Shenzhen from Jan 1 to Feb 28, 2020. COVID-19 case was defined in accordance with the WHO interim guidelines and the National Guidelines in Diagnosis and Treatment Scheme for COVID-19 (Sixth edition) (8, 9) . keywords: cases; covid-19; funder; license; medrxiv; preprint cache: cord-319770-ddq2q1pg.txt plain text: cord-319770-ddq2q1pg.txt item: #119 of 178 id: cord-320930-9yiu0080 author: Liu, Zeming title: Association Between Diabetes and COVID-19: A Retrospective Observational Study With a Large Sample of 1,880 Cases in Leishenshan Hospital, Wuhan date: 2020-07-14 words: 3153 flesch: 46 summary: We found that COVID-19 patients with DM were older and the proportion of patients with cardiovascular disease were higher among COVID-19 patients with DM than COVID-19 patients without DM. Conclusions: Our study results suggested that diabetes had no effect on the prognosis of COVID-19 patients but had a negative association with their clinical courses. keywords: cases; covid-19; diabetes; disease; patients; study cache: cord-320930-9yiu0080.txt plain text: cord-320930-9yiu0080.txt item: #120 of 178 id: cord-320953-1st77mvh author: Overton, ChristopherE. title: Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example date: 2020-07-04 words: 15723 flesch: 44 summary: We also develop household models to investigate the impact of different intervention/control strategies. Although there is now a rich theoretical literature on households models [7, 8, 9] , the mainstream methodological tools in this research area present important limitations that make them not directly applicable to studying these control policies. keywords: adherence; care; cases; contact; data; epidemic; household; individual; infection; isolation; model; number; outbreak; period; rate; time cache: cord-320953-1st77mvh.txt plain text: cord-320953-1st77mvh.txt item: #121 of 178 id: cord-320955-xhp96abg author: Allam, Zaheer title: The First 50 days of COVID-19: A Detailed Chronological Timeline and Extensive Review of Literature Documenting the Pandemic date: 2020-07-24 words: 4759 flesch: 51 summary: Researchers Develop First Diagnostic Test for Novel Coronavirus in China Cluster of Pneumonia Cases Caused by a Novel Coronavirus Event Background COVID-19 Update: Cluster of Pneumonia Cases Associated With Novel Coronavirus e Wuhan, China -2019 China's New SARS-like Virus Has Spread to Japan, But we Still Know Very Little About it Clinical Features of Patients Infected With 2019 Novel Coronavirus in Wuhan Report 1: Estimating the Potential Total Number of Novel Coronavirus Cases in Wuhan City Wuhan Wet Market WeChat Saw Spikes in the Terms 'SARS,' 'Coronavirus,' and 'Shortness of Breath Japan Confirms First Case of Infection From Wuhan Coronavirus; keywords: 2019; cases; china; coronavirus; health; market; new; virus; wuhan cache: cord-320955-xhp96abg.txt plain text: cord-320955-xhp96abg.txt item: #122 of 178 id: cord-321358-plxz5mkg author: Zheng, Jun title: SARS-CoV-2: an Emerging Coronavirus that Causes a Global Threat date: 2020-03-15 words: 4779 flesch: 48 summary: Severe illness can be caused by the remaining three viruses, namely SARS-CoV, which resulted in the outbreak of SARS in 2002 and 2003 The genome sequence of SARS-CoV-2 (WH-Human_1) was first released and shared by China on 10 Jan [12] . keywords: coronavirus; cov-2; infection; novel; patients; pneumonia; sars; transmission; viruses; wuhan cache: cord-321358-plxz5mkg.txt plain text: cord-321358-plxz5mkg.txt item: #123 of 178 id: cord-321727-xyowl659 author: Wang, Lishi title: Real-time estimation and prediction of mortality caused by COVID-19 with patient information based algorithm date: 2020-07-20 words: 5130 flesch: 61 summary: The PIBA uses patient data in real-time to build a model that estimates and predicts death rates for the near future. D i / P i−n (death rate at accumulative numbers) where M i = mortality rate, D i = the cumulative numbers of deaths on day i, P i = the cumulative numbers of patients on day keywords: data; days; death; death rate; number; patients; piba; rate cache: cord-321727-xyowl659.txt plain text: cord-321727-xyowl659.txt item: #124 of 178 id: cord-323481-uz6usokd author: Wang, Yixuan title: Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures date: 2020-03-29 words: 2959 flesch: 36 summary: med Rxiv First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures Notice on the issuance of strategic guidelines for diagnosis and treatment of novel coronavirus (2019-nCoV) infected pneumonia Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike The keypoints in treatment of the critical coronavirus disease 2019 patient Presumed asymptomatic carrier transmission of COVID-19 T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan Mental health care for medical staff in China during the COVID-19 outbreak Pathogenicity and transmissibility of 2019-nCoV-a quick overview and comparison with other emerging viruses. Microbes Infect Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak Severe acute respiratory syndrome: historical, epidemiologic, and clinical features Analysis of spatiotemporal characteristics of pandemic SARS spread in Mainland China Epidemic and emerging coronaviruses (severe acute respiratory syndrome and Middle East respiratory syndrome) SARS and MERS: recent insights into emerging coronaviruses Nosocomial transmission of emerging viruses via aerosol-generating medical procedures Emergence of MERS-CoV in the Middle East: origins, transmission, treatment, and perspectives A comprehensive collection of systems biology data characterizing the host response to viral infection Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments Clinical characteristics of 2019 novel coronavirus infection in China Coronavirus as a possible cause of severe acute respiratory syndrome Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection Guidelines for the prevention and treatment of SARS SARS-associated viral hepatitis caused by a novel coronavirus: report of three cases Analysis of SARS inpatients in Beijing in 2003 Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Hospital outbreak of Middle East respiratory syndrome coronavirus State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-COV) in humans Clinical features and viral diagnosis of two cases of infection with Middle East respiratory syndrome coronavirus: a report of nosocomial transmission Family cluster of Middle East respiratory syndrome coronavirus infections National Health and Family Planning Commission of People's Republicao of China. keywords: china; coronavirus; covid-19; novel; patients; pneumonia; sars; syndrome cache: cord-323481-uz6usokd.txt plain text: cord-323481-uz6usokd.txt item: #125 of 178 id: cord-323882-127c5bve author: Yu, Wen-Bin title: Decoding the evolution and transmissions of the novel pneumonia coronavirus (SARS-CoV-2 / HCoV-19) using whole genomic data date: 2020-05-17 words: 5584 flesch: 48 summary: In the absence of information on potential intermediary reservoirs, the origin and transmission pattern of SARS-CoV-2 are still unresolved (Wong et al., 2020) . In addition, the low level of radiation exposure on longdistance international flights (Bottollier-Depois et al., 2000) may have accelerated mutation rates of SARS-CoV-2 (Shibai et al., 2017) . keywords: coronavirus; cov-2; haplotypes; human; patients; samples; sars; wuhan cache: cord-323882-127c5bve.txt plain text: cord-323882-127c5bve.txt item: #126 of 178 id: cord-324559-p92y5er2 author: None title: cord-324559-p92y5er2 date: None words: 14724 flesch: 44 summary: Increasing reports on human PRV infection cases in China have recently indicated that PRV poses a significant threat to public health in China, especially in people in close contact with sick pigs and/or related pork products/contaminants. 3 , 8 Here we explored a simple data-driven, Boltzmann functionbased approach for estimation only based on the daily cumulative number of confirmed cases of SARS-CoV-2 (Note: the rational for Boltzmann function-based regression analysis is presented in supporting information (SI) file). keywords: 2019; cases; china; colistin; control; data; disease; gene; health; human; infection; isolates; laboratory; novel; number; outbreak; patients; pcr; pertussis; pjp; pneumoniae; prv; resistance; table; time; treatment cache: cord-324559-p92y5er2.txt plain text: cord-324559-p92y5er2.txt item: #127 of 178 id: cord-325012-yjay3t38 author: Chen, Ze-Liang title: Distribution of the COVID-19 epidemic and correlation with population emigration from Wuhan, China date: 2020-02-28 words: 3847 flesch: 55 summary: Time and location information on COVID-19 cases was extracted and analyzed using ArcGIS and WinBUGS software. Determining case distribution and its correlation with population emigration from Wuhan in the early stage of the epidemic is of great importance for early warning and for the prevention of future outbreaks. keywords: cases; hubei; january; number; province; risk; time; wuhan cache: cord-325012-yjay3t38.txt plain text: cord-325012-yjay3t38.txt item: #128 of 178 id: cord-325032-3x5wklr4 author: Jiang, Shanhe title: Semiformal Organizations and Control During the COVID-19 Crisis in China date: 2020-10-30 words: 6935 flesch: 43 summary: Semiformal social control is the mix of formal and informal controls (Huang 1993a (Huang , 1993b (Huang , 2010 . Semiformal social control can be manifested in diverse ways in China. keywords: china; community; control; government; importance; jiang; organizations; service cache: cord-325032-3x5wklr4.txt plain text: cord-325032-3x5wklr4.txt item: #129 of 178 id: cord-326721-2v5wkjrq author: Xiao, Wenlei title: A Cybernetics-based Dynamic Infection Model for Analyzing SARS-COV-2 Infection Stability and Predicting Uncontrollable Risks date: 2020-03-17 words: 4481 flesch: 51 summary: As the models are strongly featured by cities, we name the two types of models as Shanghai model and Wuhan model. City case studies are demonstrated for verification and validation. keywords: cases; cities; epidemic; infection; model; preprint; wuhan cache: cord-326721-2v5wkjrq.txt plain text: cord-326721-2v5wkjrq.txt item: #130 of 178 id: cord-326804-5psqro9d author: Wei, Chen title: The focus and timing of COVID-19 pandemic control measures under healthcare resource constraints date: 2020-04-19 words: 4603 flesch: 49 summary: The importance of transmission control in turn increases by 65% with a 7-day delay. Furthermore, prolonging outbreak duration by applying an intermediate, rather than strict, transmission control would not prevent hospital overload regardless of bed capacity, and would likely result in a high ratio (21% ~ 84%) of the population being infected but not treated. keywords: figure; license; medrxiv; medrxiv preprint; number; preprint; transmission; wuhan cache: cord-326804-5psqro9d.txt plain text: cord-326804-5psqro9d.txt item: #131 of 178 id: cord-327096-m87tapjp author: Peng, Liangrong title: Epidemic analysis of COVID-19 in China by dynamical modeling date: 2020-02-18 words: 4367 flesch: 55 summary: 5a -b, the predicted cumulative number of quarantined cases and the current number of exposed cases plus infectious cases are plotted for next 30 days as well as for a shorter period of next 13 days. And then for each fixed γ −1 , we explore its influence on other parameters (β = 1 nearly unchanged), initial values, as well as the population dynamics of quarantined cases and infected cases during best fitting. keywords: cases; epidemic; hubei; medrxiv; preprint; time; wuhan cache: cord-327096-m87tapjp.txt plain text: cord-327096-m87tapjp.txt item: #132 of 178 id: cord-327716-ehm4fgos author: Zhou, Can title: Evaluating new evidence in the early dynamics of the novel coronavirus COVID-19 outbreak in Wuhan, China with real time domestic traffic and potential asymptomatic transmissions date: 2020-02-18 words: 5033 flesch: 53 summary: With updated real time domestic traffic data, this study aims to update the current status of the COVD-19 outbreak in the city of Wuhan with the alternative information from the evacuees between the end of January and the start of February. This study integrates the recent infection data on the early dynamics of the COVD-19 outbreak in Wuhan, China with updated real time domestic traffic data. keywords: author; international; license; medrxiv; model; preprint; wuhan cache: cord-327716-ehm4fgos.txt plain text: cord-327716-ehm4fgos.txt item: #133 of 178 id: cord-328687-clr1e9p6 author: Zhou, Fuling title: Tracing asymptomatic SARS-CoV-2 carriers among 3674 hospital staff:a cross-sectional survey date: 2020-09-15 words: 3722 flesch: 40 summary: Thereafter, asymptomatic staff were re-examined weekly for 3 weeks until April 16, 2020. Our hospital had completed COVID-19 screening of 3674 staff without clinical symptoms, the results showed the proportion of asymptomatic infected staff was 0.76%. keywords: asymptomatic; cov-2; covid-19; hospital; igg; igm; sars; staff; test cache: cord-328687-clr1e9p6.txt plain text: cord-328687-clr1e9p6.txt item: #134 of 178 id: cord-328787-r0i3zo6t author: Xue, Ling title: A data-driven network model for the emerging COVID-19 epidemics in Wuhan, Toronto and Italy date: 2020-06-01 words: 5330 flesch: 55 summary: βks k k k −1 k P (k |k)i k represents the fraction of nodes with degree k infected by symptomatically infected nodes, and σβks k k k −1 k P (k |k)a k = βks k k k −1 k P (k |k)σa k represents the fraction of nodes with degree k infected by asymptomatically infected nodes. The term k 2 − k k represents the average excess degree of nodes in the network keywords: degree k; epidemic; individuals; k k; model; number; size cache: cord-328787-r0i3zo6t.txt plain text: cord-328787-r0i3zo6t.txt item: #135 of 178 id: cord-328859-qx7kvn0u author: Zhu, Hongjun title: Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study date: 2020-09-21 words: 6177 flesch: 51 summary: Computing Asymptotic behavior and stability in epidemic models Stability analysis for a vector disease model The generalized discrete-time epidemic model with immunity: a synthesis Transmission dynamics and control of severe acute respiratory syndrome The mathematics of infectious diseases Some evolutionary stochastic processes A simple stochastic epidemic Analysis of an SEIRS epidemic model with two delays An approximate maximum likelihood estimator for chain binomial models See [14] and [25] for an extensive review of classic epidemic models. keywords: covid-19; epidemic; individuals; infectives; model; number; period; seir; time; wuhan cache: cord-328859-qx7kvn0u.txt plain text: cord-328859-qx7kvn0u.txt item: #136 of 178 id: cord-332387-rmmmhrjy author: Ma, Chang-Jin title: Air Quality Variation in Wuhan, Daegu, and Tokyo during the Explosive Outbreak of COVID-19 and Its Health Effects date: 2020-06-09 words: 6641 flesch: 62 summary: As mentioned above, on 23 January 2020, the central government of China imposed a lockdown in Wuhan (see Figure 3 ) and other cities in Hubei, when the cumulative confirmed cases reached 1410. As mentioned above, on 23 January 2020, the central government of China imposed a lockdown in Wuhan (see Figure 3 ) and other cities in Hubei, when the cumulative confirmed cases reached 1,410. keywords: children; city; concentration; covid-19; daegu; pm2.5; tokyo; wuhan; year cache: cord-332387-rmmmhrjy.txt plain text: cord-332387-rmmmhrjy.txt item: #137 of 178 id: cord-333226-o23da4x2 author: Wang, Yuke title: Strongly Heterogeneous Transmission of COVID-19 in Mainland China: Local and Regional Variation date: 2020-06-19 words: 4253 flesch: 47 summary: As of 23 January 2020, confirmed COVID-19 cases have been reported in 29 provinces of mainland China and nine countries and areas outside of mainland China (10, 11) . And in third place, we collected epidemic curve data: numbers of cases (total of 6941) by province and date of confirmation from the Wikipedia page of COVID-19 cases in mainland China (18) and combined these data with detailed information, wherever available, about travel history and location (city and district) extracted from announcements of the Health Commissions of the provinces. keywords: cases; covid-19; interval; numbers; reproduction; transmission; wuhan cache: cord-333226-o23da4x2.txt plain text: cord-333226-o23da4x2.txt item: #138 of 178 id: cord-333262-xvfl7ycj author: Robson, B. title: COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles’ heel conserved region to minimize probability of escape mutations and drug resistance date: 2020-04-11 words: 21686 flesch: 45 summary: Not least, protein binding sites are often partially disordered before binding, and in any case there may be several binding modes. Several three dimensional structures are known for ACE2 complexed with SARS spike protein e.g. protein data bank (PDB) entry (6ACG) and of variants of the latter (e.g. TMPRSS2 protein data bank entry 2OQ5). keywords: ace2; acid; amino; binding; compounds; coronavirus; cov-2; data; dehydrogenase; design; e.g.; emodin; entry; human; krsfiedllfnkv; like; molecules; motif; paper; peptides; pharmacophore; present; protein; residues; sars; sequence; site; spike; studies; type; vaccine; virus cache: cord-333262-xvfl7ycj.txt plain text: cord-333262-xvfl7ycj.txt item: #139 of 178 id: cord-333581-icp0xwhx author: Aziz, Muhammad title: Gastrointestinal predictors of severe COVID-19: systematic review and meta-analysis date: 2020-07-30 words: 4314 flesch: 38 summary: Given the association of diarrhea with severe COVID-19 disease, based on our meta-analysis results, COVID-19 patients with diarrhea should be stratified into a high-risk group for developing severe disease as described above and managed accordingly. Articles were selected if they reported data on COVID-19 patients with respect to gastrointestinal symptoms (diarrhea, abdominal pain, and nausea/vomiting) or laboratory findings (serum AST, ALT, or TB). keywords: analysis; characteristics; clinical; coronavirus; covid-19; disease; patients; studies; study cache: cord-333581-icp0xwhx.txt plain text: cord-333581-icp0xwhx.txt item: #140 of 178 id: cord-335460-g8rsiiy7 author: Wu, Yu-ping title: CT manifestations of the coronavirus disease 2019 of imported infection versus second-generation infection in patients outside the original district (Wuhan, China) of this disease: An observational study date: 2020-05-22 words: 3370 flesch: 43 summary: [18] [19] Based on the comparison of CT density score between groups, we can presume that the COVID-19 in second-generation infected patients could be milder when compared to those with imported infection. The rate of severity and mortality in COVID-19 patients from Wuhan were significantly higher than that in other regions outside Wuhan, suggesting patients infected in the original district (Wuhan, China) of this disease may have more rapid aggravation. keywords: china; covid-19; group; infection; patients cache: cord-335460-g8rsiiy7.txt plain text: cord-335460-g8rsiiy7.txt item: #141 of 178 id: cord-336546-wcxqn5z2 author: Xi, Aiqi title: Epidemiological and clinical characteristics of discharged patients infected with SARS‐CoV‐2 on the Qinghai plateau date: 2020-05-21 words: 2441 flesch: 50 summary: A new coronavirus associated with human respiratory disease in China A pneumonia outbreak associated with a new coronavirus of probable bat origin A Novel Coronavirus from Patients with Pneumonia in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention WHO. We did not measure the antibody concentrations in severe patients before and after convalescent plasma transfusion, so it is difficult to accurately evaluate the efficacy related to convalescent plasma. keywords: cases; coronavirus; covid-19; patients; qinghai; wuhan cache: cord-336546-wcxqn5z2.txt plain text: cord-336546-wcxqn5z2.txt item: #142 of 178 id: cord-336963-evjmz49u author: Chen, Dong title: Exposure to SARS-CoV-2 in a high transmission setting increases the risk of severe COVID-19 compared to exposure to a low transmission setting? date: 2020-06-05 words: 471 flesch: 51 summary: In conclusion, our study highlights that SARS-CoV-2 infection in a hotspot or epicentre with high transmission intensity may adversely impact mortality rates compared to infection in a low transmission area. But maybe there is another factor inherent to high transmission settings that lead to a higher case fatality rate as observed in our study? keywords: study; wuhan cache: cord-336963-evjmz49u.txt plain text: cord-336963-evjmz49u.txt item: #143 of 178 id: cord-337324-jxtch47t author: Qian, Guo-Qing title: Epidemiologic and Clinical Characteristics of 91 Hospitalized Patients with COVID-19 in Zhejiang, China: A retrospective, multi-centre case series date: 2020-02-25 words: 3337 flesch: 55 summary: In this sample 40 (43.96%) patients had contracted the diseases from local cases, 31 (34.07%) patients had been to Wuhan/Hubei, 8 (8.79%) cases had contacted with people from Wuhan, 11 (12.09%) cases were confirmed aircraft transmission. Local cases are defined as follows: 8 patients had within the past two weeks had contact with personnel who had been in Wuhan/Hubei, these are the first generation of local cases (G1). keywords: cases; clinical; covid-19; license; patients; preprint; wuhan cache: cord-337324-jxtch47t.txt plain text: cord-337324-jxtch47t.txt item: #144 of 178 id: cord-337809-bxvgr6qg author: Xiong, Yong title: Family cluster of three recovered cases of pneumonia due to severe acute respiratory syndrome coronavirus 2 infection date: 2020-05-04 words: 1742 flesch: 48 summary: Our observations suggest the importance of preventing family transmission and the efficacy of current integrated treatment for mild/moderate pneumonia in COVID-19 cases. Our observations suggest the importance of preventing family transmission and the efficacy of current integrated treatment for mild/ moderate pneumonia in COVID-19 cases. keywords: coronavirus; days; family; patients; transmission cache: cord-337809-bxvgr6qg.txt plain text: cord-337809-bxvgr6qg.txt item: #145 of 178 id: cord-338001-jig46hsk author: Ong, Jacqueline S. M. title: Coronavirus Disease 2019 in Critically Ill Children: A Narrative Review of the Literature date: 2020-04-21 words: 3420 flesch: 43 summary: One or more caregivers usually accompany pediatric patients and this too needs to be taken into account when considering the care of COVID-19 patients. Children do not appear to account for a large proportion of COVID-19 disease. keywords: care; children; coronavirus; covid-19; disease; hospital; patients; sars; staff cache: cord-338001-jig46hsk.txt plain text: cord-338001-jig46hsk.txt item: #146 of 178 id: cord-338231-uni4aqxo author: Shi, Puyu title: Clinical characteristics of imported and second-generation coronavirus disease 2019 (COVID-19) cases in Shaanxi outside Wuhan, China: a multicentre retrospective study date: 2020-09-30 words: 4308 flesch: 52 summary: The ages of severe patients were significantly older than that of non-severe patients (median, 56 years vs. 41 years, P < 0.05). Moreover, the proportion of patients aged 65 or older was higher (32.6% vs. 5.7%, P < 0.05), and the proportion of patients aged 14-30 was lower (4.3% vs. 21.6%, P < 0.05) in the group of severe patients than in non-severe patients ( Table 1) . keywords: cases; clinical; covid-19; median; patients; study; table; wuhan cache: cord-338231-uni4aqxo.txt plain text: cord-338231-uni4aqxo.txt item: #147 of 178 id: cord-339044-qy4jab37 author: Li, Man title: Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study date: 2020-08-25 words: 2593 flesch: 46 summary: In addition to age factors, we also found D-dimer levels >1,000 ng/L, and platelet counts < 125 × 10 9 /L on admission were associated with fatal outcomes in COVID-19 patients. (21) have reported that while COVID-19 patients with significantly elevated platelet count during treatment were on an average hospitalized longer, the platelet count at admission was lower in severely ill patients (169.67 ± 48.95) compared to those who were not severely ill (192.26 ± 58.12). keywords: covid-19; disease; factors; patients; risk; study; wuhan cache: cord-339044-qy4jab37.txt plain text: cord-339044-qy4jab37.txt item: #148 of 178 id: cord-339743-jxj10857 author: Liu, H. title: Synchronized travel restrictions across cities can be effective in COVID-19 control date: 2020-04-06 words: 4698 flesch: 49 summary: Our analysis shows that: (1) all mobility patterns correlated with the spread of the coronavirus in Chinese cities outside Hubei, while the corrleations droppd with the implemetation of travel restrictions; (2) the cumulative confirmed cases in two weeks after the Wuhan lockdown was mainly brought by three patterns of inter-city population movement, while those in the third and fourth weeks after was significantly influenced by the number of intra-city population movement; (3) the local travel restrictions imposed by cities outside Hubei have averted 1,960 (95%PI: 1,474-2,447) more infections, taking 22.4% (95%PI: 16.8%-27.9%) of confirmed ones, in two weeks after the Wuhan lockdown, while more synchronized implementation would further decrease the number of confirmed cases in the same period by 15.7% (95%PI:15.4%-16.0%) or 1,378 (95%PI: 1,353-1,402) cases; and (4) local travel restrictions on different mobility patterns have different degrees of protection on cities with or without initial confirmed cases until the Wuhan lockdown. The daily population outflow from Hubei (excluding Wuhan), inter-city population movement, and intra-city population movement after Feb 03, 2019, aligned by the Chinese lunar calendar with Jan 23, 2020, were used as proxy mobility data for the no local travel restrictions status in cities outside Hubei. keywords: cities; city; hubei; mobility; population; wuhan cache: cord-339743-jxj10857.txt plain text: cord-339743-jxj10857.txt item: #149 of 178 id: cord-340369-y8o5j2be author: Zhang, Juanjuan title: Age profile of susceptibility, mixing, and social distancing shape the dynamics of the novel coronavirus disease 2019 outbreak in China date: 2020-03-20 words: 2536 flesch: 40 summary: As transmission intensifies in other countries, the interplay between age, contact patterns, social distancing, susceptibility to infection and disease, and COVID-19 dynamics remains unclear. We estimated that limiting contact patterns to those observed during vacations would interrupt transmission for baseline R0 up to 1.5 (Fig. 2C) . keywords: age; contacts; covid-19; infection; outbreak; wuhan cache: cord-340369-y8o5j2be.txt plain text: cord-340369-y8o5j2be.txt item: #150 of 178 id: cord-341135-gmi1ewc2 author: Kucharski, Adam J title: Early dynamics of transmission and control of COVID-19: a mathematical modelling study date: 2020-02-02 words: 3466 flesch: 40 summary: The outbreak was first identified in Wuhan, China, in December 2019, with the majority of early cases being reported in the city. We used an additional two datasets for comparison with model outputs: daily number of new exported cases from Wuhan (or lack thereof) in countries with high connectivity to Wuhan (i.e. top 20 most at risk), by date of confirmation, as of 10th February 2020; data on new confirmed cases reported in Wuhan between 16 th January and 11 th February 2020 (full details in the Appendix). keywords: cases; data; january; number; transmission; wuhan cache: cord-341135-gmi1ewc2.txt plain text: cord-341135-gmi1ewc2.txt item: #151 of 178 id: cord-342012-1w3x0g42 author: Wu, Joseph T. title: Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China date: 2020-03-19 words: 5333 flesch: 48 summary: Public health control measures widely imposed in China since the Wuhan alert have also kept case numbers down elsewhere, so that their health systems are not nearly as overwhelmed beyond surge capacity, thus again perhaps leading to better outcomes 6, 8 . Let G be the cumulative number of death cases in Wuhan as of 25 February 2020 (time T). keywords: age; cases; data; death; estimates; fatality; number; table; time; wuhan cache: cord-342012-1w3x0g42.txt plain text: cord-342012-1w3x0g42.txt item: #152 of 178 id: cord-342268-azi9i2a8 author: Zhao, Shi title: Quantifying the association between domestic travel and the exportation of novel coronavirus (2019-nCoV) cases from Wuhan, China in 2020: a correlational analysis date: 2020-02-20 words: 1595 flesch: 53 summary: The outbreak is still on-going with an increasing trend in daily new cases. The association was formulated as follows: Here, c i,t represents the daily number of new cases in the ith provincial region on day t. The function E(·) is the expectation; the 'province i ' denotes the dummy variable for the ith provincial region in accounting for the heterogenicity among different provinces, and thus, α i is a locality-varying interception term. keywords: cases; china; number; wuhan cache: cord-342268-azi9i2a8.txt plain text: cord-342268-azi9i2a8.txt item: #153 of 178 id: cord-342822-d7jx06mh author: Izadi, N. title: The epidemiologic parameters for COVID-19: A Systematic Review and Meta-Analysis date: 2020-05-06 words: 3375 flesch: 42 summary: Estimation Using Japanese Passengers Data on Evacuation Flights Serial interval of novel coronavirus (COVID-19) infections Ascertainment rate of novel coronavirus disease (COVID-19) in Japan Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: framework and applications to the novel coronavirus (SARS-CoV-2) outbreak. medRxiv Estimating the daily trend in the size of the COVID-19 infected population in Wuhan Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data Time-varying transmission dynamics of Novel Coronavirus Pneumonia in China Early epidemiological assessment of the transmission potential and virulence of coronavirus disease 2019 (COVID-19) in Wuhan City: China Transmission potential of COVID-19 in Iran The Rate of Underascertainment of Novel Coronavirus (2019-nCoV) Infection: keywords: coronavirus; covid-19; license; medrxiv; novel; peer; preprint cache: cord-342822-d7jx06mh.txt plain text: cord-342822-d7jx06mh.txt item: #154 of 178 id: cord-343715-y594iewi author: Gavriatopoulou, Maria title: Organ-specific manifestations of COVID-19 infection date: 2020-07-27 words: 8776 flesch: 34 summary: Cerebrovascular disease represents another mechanism explaining neurological signs and symptoms in COVID-19 patients, although the rate of acute stroke admissions has been significantly reduced over the COVID-19 pandemic [125] . Among COVID-19 patients who suffered a stroke, the rate of cryptogenic and embolic strokes was higher, and events were more severe and affected younger patients [126, 129] . keywords: ace2; acute; cells; china; coronavirus; cov-2; covid-19; disease; infection; injury; manifestations; patients; pneumonia; sars; study; symptoms; syndrome cache: cord-343715-y594iewi.txt plain text: cord-343715-y594iewi.txt item: #155 of 178 id: cord-343767-nnx8adtl author: Liu, Ziyuan title: Path Optimization of Medical Waste Transport Routes in the Emergent Public Health Event of COVID-19: A Hybrid Optimization Algorithm Based on the Immune–Ant Colony Algorithm date: 2020-08-12 words: 6145 flesch: 43 summary: Therefore, in this paper, several temporary storage points were discussed above, according to the environmental impacts and assessment criteria, utilizing the − value method to allocate medical waste transport vehicles, and applying the immune-based ant colony algorithm, together with the tabu search algorithm, to arrange the correct pathways of waste transportation. Therefore, in this paper, several temporary storage points were discussed above, according to the environmental impacts and assessment criteria, utilizing the Q − value method to allocate medical waste transport vehicles, and applying the immune-based ant colony algorithm, together with the tabu search algorithm, to arrange the correct pathways of waste transportation. keywords: algorithm; hospitals; medical; model; number; problem; stations; transport; transport station; vehicle; waste; waste transport cache: cord-343767-nnx8adtl.txt plain text: cord-343767-nnx8adtl.txt item: #156 of 178 id: cord-344423-jhdfscyw author: Lian, Xinbo title: Impact of city lockdown on the air quality of COVID-19-hit of Wuhan city date: 2020-06-30 words: 5274 flesch: 45 summary: Regional air quality has improved significantly, but air pollution control still has a long way to go Aavo Tomasova, Jelena. Furthermore, the high density of buildings reduces the wind speed and the diffusion of air pollution . keywords: air; concentration; emissions; lockdown; pollutants; pollution; quality; traffic; wuhan cache: cord-344423-jhdfscyw.txt plain text: cord-344423-jhdfscyw.txt item: #157 of 178 id: cord-344480-6tcush4w author: Zhou, Guangbiao title: Back to the spring of Wuhan: facts and hope of COVID-19 outbreak date: 2020-03-14 words: 1568 flesch: 45 summary: [14, 15] , and a virus with 99% sequence homology to the receptor-binding domain (RBD) and 90% to the SARS-CoV-2 genome was also found in Malayan pangolins in southern China China Novel Coronavirus Investigating and Research Team. keywords: china; coronavirus; covid-19; novel; wuhan cache: cord-344480-6tcush4w.txt plain text: cord-344480-6tcush4w.txt item: #158 of 178 id: cord-344688-uu3b529c author: Song, Xue-Jun title: Pain Management During the COVID-19 Pandemic in China: Lessons Learned date: 2020-04-22 words: 2381 flesch: 45 summary: Of those infected, 22% were working in high risk departments such as infectious disease and intensive care units, while the majority (78%) worked in departments with less direct exposure to COVID-19 patients (9) . We may prepare ourselves to see more patients who previously had COVID-19 infection visiting pain clinic as the epidemic slows. keywords: care; covid-19; health; medical; pain; patients cache: cord-344688-uu3b529c.txt plain text: cord-344688-uu3b529c.txt item: #159 of 178 id: cord-345724-6u9q0ox9 author: Zhu, Xiaolin title: Spatially Explicit Modeling of 2019-nCoV Epidemic Trend based on Mobile Phone Data in Mainland China date: 2020-02-11 words: 3852 flesch: 47 summary: It shows that decay rates of cities close to Wuhan is generally lower than other cities ( Figure 5 .b), suggesting the big challenge faced by these cities to control the disease spreading. Transmission rate 2 estimated using Wuhan confirmed cases is 0.9, reflecting a high transmission around January 20. keywords: cases; cities; city; model; number; wuhan cache: cord-345724-6u9q0ox9.txt plain text: cord-345724-6u9q0ox9.txt item: #160 of 178 id: cord-347204-cafr7f38 author: Yuan, Zheming title: Modelling the effects of Wuhan’s lockdown during COVID-19, China date: 2020-07-01 words: 3946 flesch: 52 summary: However, other researchers have suggested that travel restrictions from and to Wuhan city are unlikely to have been effective in halting transmission across China. We extracted the actual number of people entering and leaving Beijing and Shanghai cities, and the number of people leaving Foshan, Nanjing, Qingdao, Shenzhen and Wuhan cities from the official website of the local municipal transport commissions. keywords: cases; china; city; covid-19; data; january; number; people; wuhan cache: cord-347204-cafr7f38.txt plain text: cord-347204-cafr7f38.txt item: #161 of 178 id: cord-347257-s0w95qdn author: Kraemer, Moritz U. G. title: The effect of human mobility and control measures on the COVID-19 epidemic in China date: 2020-03-25 words: 2032 flesch: 42 summary: Early on, the spatial distribution of COVID-19 cases in China was explained well by human mobility data. We use real-time mobility data from Wuhan and detailed case data including travel history to elucidate the role of case importation on transmission in cities across China and ascertain the impact of control measures. keywords: cases; china; coronavirus; covid-19; data; epidemic; wuhan cache: cord-347257-s0w95qdn.txt plain text: cord-347257-s0w95qdn.txt item: #162 of 178 id: cord-348327-rgikd4g8 author: Ueyama, Hiroki title: Gender Difference Is Associated With Severity of Coronavirus Disease 2019 Infection: An Insight From a Meta-Analysis date: 2020-06-19 words: 2450 flesch: 39 summary: Recognition of the clinical risk factors of severe COVID-19 infection is a high priority to effectively manage this emerging threat of the new virus. The endpoints were the rate of severe COVID-19 infection and death. keywords: analysis; coronavirus; covid-19; gender; infection; studies cache: cord-348327-rgikd4g8.txt plain text: cord-348327-rgikd4g8.txt item: #163 of 178 id: cord-349276-viq01q8l author: Shaw, Rajib title: Governance, technology and citizen behavior in pandemic: Lessons from COVID-19 in East Asia date: 2020-04-30 words: 9228 flesch: 50 summary: Here, a few critical issues on Japan's approach is described below: Diamond Princess Experiences: The Cruise ship Diamond princess arrived at the port of Yokohama on 3rd February 2020 and received world attention due to reported confirmed case in the ship. China sees a sharp increase in number of confirmed cases from the third week of January, while a sharp increase in both recovered and death from the first week of February. keywords: cases; china; control; countries; covid-19; disease; february; government; health; january; japan; korea; march; people; self; spread; virus; wuhan cache: cord-349276-viq01q8l.txt plain text: cord-349276-viq01q8l.txt item: #164 of 178 id: cord-350338-lcsa06gm author: Wang, Kun title: Clinical and laboratory predictors of in-hospital mortality in patients with COVID-19: a cohort study in Wuhan, China date: 2020-05-03 words: 2475 flesch: 45 summary: The MuLBSTA Score Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding From gene to proteinexperimental and clinical studies of ACE2 in blood pressure control and arterial hypertension Preparing for the next influenza pandemic An interferon-γ-related cytokine storm in SARS patients Corticosteroid Treatment Ameliorates Acute Lung Injury Induced by 2009 Swine Origin Influenza A (H1N1) Virus in Mice The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration Understanding the T cell immune response in SARS coronavirus infection Biochemical Aspects of Coronavirus Replication and Virus-Host Interaction Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Specific ACE2 Expression in Cholangiocytes Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Machine learning for the prediction of volume responsiveness in patients with oliguric acute kidney injury in critical care Boosted tree model reforms multimodal magnetic resonance imaging infarct prediction in acute stroke Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach Innate immune responses in the ageing lung Clinical Features Predicting Mortality Risk in Patients With Viral Pneumonia: keywords: clinical; cohort; covid-19; hospital; model; patients; study cache: cord-350338-lcsa06gm.txt plain text: cord-350338-lcsa06gm.txt item: #165 of 178 id: cord-350822-m3t7l9zw author: Mo, Yuanyuan title: Work stress among Chinese nurses to support Wuhan in fighting against COVID‐19 epidemic date: 2020-05-20 words: 3622 flesch: 51 summary: The procedures of this study were reviewed and approved by the Stress overload: A new approach to the assessment of stress National support Wuhan medical staff zero infection Global challenges in health and health care for nurses and midwives everywhere Job stress and burnout in hospital employees: Comparisons of different medical professions Analysis of nurse anxiety and its influencing factors Conscientiousness, openness to experience and extraversion as predictors of nursing work performance: A facet-level analysis Anxiety symptoms among Chinese nurses and the associated factors: A cross sectional study Psychosocial job factors and biological cardiovascular risk factors in Mexican workers COVID-19: Multiple regression analysis showed that only children, working hours per week and anxiety were the main factors affecting nurse stress (p = .000, .048, .000, respectively). keywords: anxiety; covid-19; health; load; nurses; score; stress; work cache: cord-350822-m3t7l9zw.txt plain text: cord-350822-m3t7l9zw.txt item: #166 of 178 id: cord-351167-4gpq5syb author: Koenig, Kristi L. title: 2019-nCoV: The Identify-Isolate-Inform (3I) Tool Applied to a Novel Emerging Coronavirus date: 2020-01-31 words: 3468 flesch: 40 summary: As outlined above, admission criteria for 2019-nCoV are similar to that of other patients. A novel 2019-nCoV 3I Tool is designed for frontline clinicians in the management of suspected patients. keywords: coronavirus; disease; health; inform; ncov; novel; patients; tool cache: cord-351167-4gpq5syb.txt plain text: cord-351167-4gpq5syb.txt item: #167 of 178 id: cord-351567-ifoe8x28 author: Rabi, Firas A. title: SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far date: 2020-03-20 words: 5766 flesch: 49 summary: Initial virological and clinical findings Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Controlled Trial of Ebola Virus Disease Therapeutics Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro First Case of 2019 Novel Coronavirus in the United States NIH Clinical Trial of Remdesivir to Treat COVID-19 Begins Gilead Sciences Initiates Two Phase 3 Studies of Investigational Antiviral Remdesivir for the Treatment of COVID-19 Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Protease inhibitors targeting coronavirus and filovirus entry Camostat Mesilate, Pancrelipase, and Rabeprazole Combination Therapy Improves Epigastric Pain in Early Chronic Pancreatitis and Functional Dyspepsia with Pancreatic Enzyme Abnormalities TACTIC Investigative Team a phase 1/2 trial to evaluate the pharmacokinetics, safety, and efficacy of NI-03 in patients with chronic pancreatitis: Study protocol for a randomized controlled trial on the assessment of camostat treatment in chronic pancreatitis (TACTIC) However, by that time, travelers had carried the virus to many countries, sparking memories of the previous coronavirus epidemics, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and causing widespread media attention and panic. keywords: cases; china; coronavirus; cov-2; covid-19; disease; novel; number; patients; risk; sars; wuhan cache: cord-351567-ifoe8x28.txt plain text: cord-351567-ifoe8x28.txt item: #168 of 178 id: cord-351600-bqw9ks4a author: Zhang, Shuai title: Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study date: 2020-07-16 words: 4972 flesch: 42 summary: In patients with COVID-19, plasma LDH level was reported to be higher in severe, ICU, and deceased COVID-19 patients than in mild, non-ICU-patients, and survivors In this study, we employed the clinical and laboratory features of COVID-19 patients to work out an effective and easy tool for predicting 28-day mortality. keywords: cohort; covid-19; day; hospital; mortality; patients; study; survival; wuhan cache: cord-351600-bqw9ks4a.txt plain text: cord-351600-bqw9ks4a.txt item: #169 of 178 id: cord-351651-6dbt99h0 author: Sun, Zhong title: Potential Factors Influencing Repeated SARS Outbreaks in China date: 2020-03-03 words: 4990 flesch: 53 summary: This mini-review evaluated the common epidemiological patterns of both SARS epidemics in China and identified cold, dry winter as a common environmental condition conducive for SARS virus infection to human beings. It was believed that the virus was transmitted to civet from Yunnan horseshoe bats, and civet cats carrying the virus were transported to Guangdong, which led to SARS-CoV infection on humans and SARS outbreak in Guangdong [32] . keywords: bats; china; coronavirus; cov; cov-2; covs; human; sars; sars-2; virus; wuhan cache: cord-351651-6dbt99h0.txt plain text: cord-351651-6dbt99h0.txt item: #170 of 178 id: cord-351880-iqr419fp author: Fan, Changyu title: Prediction of Epidemic Spread of the 2019 Novel Coronavirus Driven by Spring Festival Transportation in China: A Population-Based Study date: 2020-03-04 words: 8589 flesch: 45 summary: Therefore, while our research is aimed at China in the current era of migration, this research has practical implications for global public health and disease control, as floating populations are increasing in size all over the world and relationships between countries are becoming increasingly close. The prediction of floating population in Wuhan based on the statistics from previous years is presented in Table 3 , demonstrating that there were approximately 2.43 million migrants living in Wuhan for more than six months in 2019. keywords: 2019; cases; data; epidemic; hubei; ncov; number; people; population; province; wuhan cache: cord-351880-iqr419fp.txt plain text: cord-351880-iqr419fp.txt item: #171 of 178 id: cord-352030-hnm54k4r author: Liu, Jie title: Epidemiological, Clinical Characteristics and Outcome of Medical Staff Infected with COVID-19 in Wuhan, China: A Retrospective Case Series Analysis date: 2020-03-13 words: 5267 flesch: 47 summary: The exact mode of medical staff infection remains unclear. Findings The median age of medical staff included was 35 years old. keywords: coronavirus; covid-19; group; license; medical; patients; preprint; sars; staff cache: cord-352030-hnm54k4r.txt plain text: cord-352030-hnm54k4r.txt item: #172 of 178 id: cord-352509-qrzt4zva author: Chen, Haohui title: Social distance and SARS memory: impact on the public awareness of 2019 novel coronavirus (COVID-19) outbreak date: 2020-03-16 words: 3904 flesch: 56 summary: key: cord-352509-qrzt4zva authors: Chen, Haohui; Xu, Weipan; Paris, Cecile; Reeson, Andrew; Li, Xun title: Social distance and SARS memory: impact on the public awareness of 2019 novel coronavirus (COVID-19) outbreak date: 2020-03-16 journal: nan DOI: 10.1101/2020.03.11.20033688 sha: doc_id: 352509 cord_uid: qrzt4zva This study examines publicly available online search data in China to investigate the spread of public awareness of the 2019 novel coronavirus (COVID-19) outbreak. Public awareness is important in managing the spread of infectious diseases. keywords: awareness; cities; memory; outbreak; public; sars; wuhan cache: cord-352509-qrzt4zva.txt plain text: cord-352509-qrzt4zva.txt item: #173 of 178 id: cord-352797-xuaqump9 author: Bian, Xiaoen title: Influence of Asymptomatic Carriers With COVID-19 on Transplantation Resumption in Wuhan date: 2020-06-22 words: 521 flesch: 44 summary: The second group of asymptomatic cases are in the early stages of the incubation of the disease and become symptomatic over time but are contagious in the asymptomatic phase. Due to the superficial understanding of COVID-19 and presence of asymptomatic infection in Wuhan, we instituted a protocol to prevent organ donor transmission of COVID-19. keywords: asymptomatic; covid-19 cache: cord-352797-xuaqump9.txt plain text: cord-352797-xuaqump9.txt item: #174 of 178 id: cord-353862-7xe3fvd5 author: Li, Na title: Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study date: 2020-03-30 words: 3518 flesch: 49 summary: However, previous studies argued that false negative cases might be common for COVID-19 infection cases due to low virus titers, sampling at late stage of illness, and This rate was higher than in suspected patients (16.7%) and in two control groups (~5%) of our study, but lower than the rate of 44% in confirmed COVID-19 pneumonia patients reported by Chen et al. keywords: cases; covid-19; delivery; patients; pneumonia; sars; women cache: cord-353862-7xe3fvd5.txt plain text: cord-353862-7xe3fvd5.txt item: #175 of 178 id: cord-354095-4sweo53l author: Qiu, Yun title: Impacts of social and economic factors on the transmission of coronavirus disease 2019 (COVID-19) in China date: 2020-05-09 words: 12475 flesch: 49 summary: To estimate the impacts of new COVID-19 cases in other cities, we first calculate the geographic distance between a city and all other cities using the latitudes and longitudes of the centroids of each city and then calculate the weighted sum of the number Since the COVID-19 outbreak started from Wuhan, we also calculate the weighted number of COVID-19 new cases in Wuhan using the inverse of log distance as the weight. Fifth, our study uses spatially disaggregated data that cover China (except its Hubei province), while some other studies examine Wuhan city, Hubei province, China as a whole, or overseas. keywords: cases; china; cities; city; covid-19; february; health; hubei; january; measures; number; province; transmission; variables; virus; weather; weeks; wuhan cache: cord-354095-4sweo53l.txt plain text: cord-354095-4sweo53l.txt item: #176 of 178 id: cord-354717-4vrqzbof author: Linton, Natalie M. title: Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data date: 2020-02-17 words: 3130 flesch: 42 summary: SIAM Rev Stan Modeling Language Users Guide and Reference Manual, Version 2.22.0 Incubation periods of acute respiratory viral infections: A systematic review Association between severity of MERS-CoV infection and incubation period This study was made possible only through open sharing of case data from China and other countries where cases were diagnosed. keywords: cases; days; incubation; period; time; wuhan cache: cord-354717-4vrqzbof.txt plain text: cord-354717-4vrqzbof.txt item: #177 of 178 id: cord-355528-y4a1g6km author: Balla, Mamtha title: COVID-19, Modern Pandemic: A Systematic Review From Front-Line Health Care Providers’ Perspective date: 2020-03-30 words: 7523 flesch: 53 summary: Patients can catch it by breathing in droplets if they are standing within 1 m of COVID-19 patients. Drills and emergency preparedness about COVID-19 should be performed in all health care facilities involving providers who will be in touch with COVID-19 suspected patients. keywords: cases; china; coronavirus; covid-19; disease; et al; health; infection; novel; patients; pneumonia; sars; treatment cache: cord-355528-y4a1g6km.txt plain text: cord-355528-y4a1g6km.txt item: #178 of 178 id: cord-355531-1cpli8kv author: LIANG, Jingbo title: The impacts of diagnostic capability and prevention measures on transmission dynamics of COVID-19 in Wuhan date: 2020-04-06 words: 3729 flesch: 44 summary: Understanding Wuhan COVID-19 transmission dynamics and the effects of prevention approaches is of significant importance for containing virus global transmission. https://doi.org/10.1101/2020.03.31.20049387 doi: medRxiv preprint where p(m|i) represented the probability that a person with COVID-19 seek medical attention, which was assumed as 0.8; p(hosp_diag|i) t was the hospital-diagnose rate, the probability that a person infected with COVID-19 would be diagnosed as COVID-19 case by the hospital; (Proportion of documented infections) t , the probability that a person infected with COVID-19 would be confirmed and documented by hospitals, could be estimated by the conduct of p(m|i) and p(hosp_diag|i) t . keywords: cases; infections; license; medrxiv; preprint; transmission; wuhan cache: cord-355531-1cpli8kv.txt plain text: cord-355531-1cpli8kv.txt